Kajikawa Tetsuhiro 梶川哲宏

… Alternative Names

KAJIKAWA TETSUHIRO 梶川哲宏

KAJIKAWA Tetsuhiro 梶川哲宏

Less

Researcher Number	90611252
Other IDs
Affiliation (Current)	2025: 東北大学, 大学病院, 講師
Affiliation (based on the past Project Information) *help	2022 – 2024: 東北大学, 大学病院, 講師 2011 – 2013: 大阪大学, 歯学部附属病院, 医員
Review Section/Research Field	Principal Investigator Medium-sized Section 57:Oral science and related fields / Basic Section 57030:Conservative dentistry-related / Periodontology / Periodontal dentistry Except Principal Investigator Basic Section 57030:Conservative dentistry-related / Medium-sized Section 57:Oral science and related fields / Periodontal dentistry
Keywords	Principal Investigator 歯周炎 / 口腔疾患治療法 / 死細胞除去 / 新規キメラ受容体 / CHEF / 免疫細胞 / 核内受容体 / マクロファージ / 好中球 / 歯周組織 … More / エフェロサイトーシス / 細胞移植治療 / TCR / iPS / iPS化 / Dysbiosis / 絹糸結紮歯周炎モデル / TCRレパトア / Dysbiotic細菌叢 / 歯周病 / MAIT細胞 / 歯周病疾患感受性 / PLAP-1遺伝子多型 / 疾患感受性 / 遺伝子多型 / 歯根膜 / PLAP-1 … More Except Principal Investigator 歯周組織再生 / 侵襲性歯周炎 / デザイナー細胞 / PheWAS解析 / シングルセルゲノミクス解析 / 歯周炎 / ゲノム解析 / 再生 / 歯周組織 / バイオインフォマティクス解析 / 微量RNA-seq / ATAC-seq / エピジェネティクス / エピゲノム / 歯周病 / PLAP-1 / 遺伝子多型解析 / 疾患由来iPS細胞 / 疾患由来 iPS細胞 / 細胞移植 / 歯根膜細胞 / 歯周組織再生療法 Less

CHEF作製技術を応用した超効率死細胞除去による口腔疾患治療法の革命Principal Investigator
- Principal Investigator
  
  梶川哲宏
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Tohoku University
シングルセルゲノミクスとPheWAS解析による歯周病の個別化医療・予防の確立
- Principal Investigator
  
  山田聡
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Tohoku University
歯周組織特異的CAR-MSC細胞を用いた革新的な歯周組織再生移植治療への挑戦
- Principal Investigator
  
  山田聡
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Tohoku University
Development of Dysbiotic Microbiota-specific MAIT Cells and Their Application to the Treatment for PeriodontitisPrincipal Investigator
- Principal Investigator
  
  KAJIKAWA TETSUHIRO
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Tohoku University
エフェロサイトーシスを基軸とした歯周組織恒常性維持機構の解明と治療への応用Principal Investigator
- Principal Investigator
  
  梶川哲宏
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Tohoku University
再生指向型エピゲノムに基づく歯周組織再生術前診断法と精密化療法の樹立
- Principal Investigator
  
  鈴木茂樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Tohoku University
Analysis of the molecular pathogenesis of aggressive periodontitis based on disease-derived induced pluripotent stem cells and PLAP-1
- Principal Investigator
  
  Yamada Satoru
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Tohoku University
歯根膜特異的分子PLAP-1遺伝子多型の歯周病疾患感受性への関与Principal Investigator
- Principal Investigator
  
  梶川哲宏
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontology
- Research Institution
  Osaka University
Gene polymorphism in PLAP-1regulates inflammation of periodontal disease.Principal Investigator
- Principal Investigator
  
  KAJIKAWA Tetsuhiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka University
Development of novel minimal intervention methods for periodontal tissue regeneration therapy
- Principal Investigator
  
  YAMADA Satoru
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka University

All 2023 2022 2021 2014 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Mice Lacking PLAP-1/Asporin Show Alteration of Periodontal Ligament Structures and Acceleration of Bone Loss in Periodontitis2023
- Author(s)
  Kinoshita Masaki、Yamada Satoru、Sasaki Junichi、Suzuki Shigeki、Kajikawa Tetsuhiro、Iwayama Tomoaki、Fujihara Chiharu、Imazato Satoshi、Murakami Shinya
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 21 Pages: 15989-15989
- DOI
  10.3390/ijms242115989
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19611, KAKENHI-PROJECT-23K24524, KAKENHI-PROJECT-23K27767
[Journal Article] Mouse Model of Loeys?Dietz Syndrome Shows Elevated Susceptibility to Periodontitis via Alterations in Transforming Growth Factor-Beta Signaling2021
- Author(s)
  Yamada Satoru、Tsushima Kenichiro、Kinoshita Masaki、Sakashita Hiromi、Kajikawa Tetsuhiro、Fujihara Chiharu、Yuan Hang、Suzuki Shigeki、Morisaki Takayuki、Murakami Shinya
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 12 Pages: 1-13
- DOI
  10.3389/fphys.2021.715687
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10104, KAKENHI-PROJECT-20H03862, KAKENHI-PROJECT-19K08535, KAKENHI-PROJECT-21K16991
[Journal Article] Inhibitory effects of PLAP-1/asporin on periodontal ligament cells2014
- Author(s)
  T Kajikawa, S Yamada, T Tauchi, T Awata, S Yamaba, C Fujihara, S Murakami
- Journal Title
  
  Journal of Dental Research
  
  Volume: 93 Issue: 4 Pages: 400-405
- DOI
  10.1177/0022034513520549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249086, KAKENHI-PROJECT-23390478, KAKENHI-PROJECT-25670884, KAKENHI-PROJECT-25862047
[Journal Article] Effects of L-ascorbic acid 2-phosphate magnesium salt on the properties of human gingival fibroblasts2012
- Author(s)
  Tsutsumi K, Fujikawa H, Kajikawa T, Takedachi M, Yamamoto T, Murakami S
- Journal Title
  
  J Periodontal Res
  
  Volume: 47 Pages: 263-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890109
[Journal Article] Role of ferritin in the cytodifferentiation of periodontal ligament cells2012
- Author(s)
  Hou J, Yamada S, Kajikawa T, Ozaki N, Awata T, Yamaba S, Murakami S
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 426 Pages: 643-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890109
[Presentation] Analysis of periodontal MAIT cells using the ligature-induced periodontitis model2023
- Author(s)
  野田武聖, 梶川哲宏, 佐藤理恵, Li Qingling, 山田聡
- Organizer
  The 71st Annual Meeting of Japanese Association for Dental Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19612
[Presentation] MAIT Cells Exacerbate Alveolar Bone Loss in Periodontitis Associated with LAD12023
- Author(s)
  梶川哲宏
- Organizer
  The 71st Annual Meeting of Japanese Association for Dental Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19612
[Presentation] The pivotal role of MAIT cells in periodontitis associated with LAD12023
- Author(s)
  梶川哲宏
- Organizer
  3rd International Conference on Oral Mucosal Immunity and Microbiome
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24523
[Presentation] 実験的歯周炎モデルマウスにおける好中球誘導性エフェロサイトーシスの検討2023
- Author(s)
  佐藤理恵, 梶川哲宏, 野田武聖, Li Qingling, 山田聡
- Organizer
  第66回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-23K24523
[Presentation] 白血球接着不全症I型(LAD-I)関連歯周炎の発症メカニズムと治療法2022
- Author(s)
  梶川哲宏
- Organizer
  第60回日本口腔科学会北日本地方部会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24523
[Presentation] Inhibitory effects of D14-PLAP-1 on periodontal ligament cell differentiation2012
- Author(s)
  梶川哲宏
- Organizer
  90th General Session of the IADR
- Place of Presentation
  Iguacu Falls, Brazil
- Data Source
  KAKENHI-PROJECT-23890109
[Presentation] PLAP-1 遺伝子多型の歯根膜恒常性における役割2011
- Author(s)
  梶川哲宏
- Organizer
  第54回春季日本歯周病学会学術大会
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-23890109
[Presentation] PLAP-1遺伝子多型の歯根膜恒常性における役割2011
- Author(s)
  梶川哲宏
- Organizer
  第54回春季日本歯周病学会学術大会
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-23890109
[Presentation] Analysis of Cathepsin K in human periodontal ligament cells2010
- Author(s)
  N. OZAKI, S. YAMADA, C. FUJIHARA, T. TAUCHI, T. KAJIKAWA, T. AWATA, Y. OZAWA, S. MURAKAMI
- Organizer
  第58回国際歯科研究学会日本部会(JADR)
- Place of Presentation
  小倉市
- Year and Date
  2010-10-19
- Data Source
  KAKENHI-PROJECT-22659379
[Presentation] ヒトPLAP-1発現アデノウイルスの作製
- Author(s)
  梶川哲宏，山田聡，粟田敏仁，山羽聡子，阪下裕美，津島賢一朗，村上伸也
- Organizer
  第56回秋季日本歯周病学会学術大会
- Place of Presentation
  前橋市民文化会館
- Data Source
  KAKENHI-PROJECT-25862047

1. YAMADA Satoru (40359849)

# of Collaborated Projects: 8 results

# of Collaborated Products: 6 results
2. 鈴木茂樹 (30549762)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
3. 向阪幸彦 (10760457)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 根本英二 (40292221)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 村上伸也 (70239490)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. NOZAKI Takenori (30263304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HASHIKAWA Tomoko (00362682)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OZAKI Nobuhiro (80632132)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 森崎隆幸 (30174410)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 江草宏 (30379078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 大槻晃史 (30778022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 大谷栄毅 (60982337)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 齋藤正寛 (40215562)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kajikawa Tetsuhiro 梶川 哲宏

KAJIKAWA TETSUHIRO 梶川 哲宏

KAJIKAWA Tetsuhiro 梶川 哲宏

Research Projects

Research Products

Co-Researchers

CHEF作製技術を応用した超効率死細胞除去による口腔疾患治療法の革命Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

シングルセルゲノミクスとPheWAS解析による歯周病の個別化医療・予防の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

歯周組織特異的CAR-MSC細胞を用いた革新的な歯周組織再生移植治療への挑戦

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Dysbiotic Microbiota-specific MAIT Cells and Their Application to the Treatment for PeriodontitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

エフェロサイトーシスを基軸とした歯周組織恒常性維持機構の解明と治療への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

再生指向型エピゲノムに基づく歯周組織再生術前診断法と精密化療法の樹立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the molecular pathogenesis of aggressive periodontitis based on disease-derived induced pluripotent stem cells and PLAP-1

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

歯根膜特異的分子PLAP-1遺伝子多型の歯周病疾患感受性への関与Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gene polymorphism in PLAP-1regulates inflammation of periodontal disease.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel minimal intervention methods for periodontal tissue regeneration therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Mice Lacking PLAP-1/Asporin Show Alteration of Periodontal Ligament Structures and Acceleration of Bone Loss in Periodontitis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mouse Model of Loeys?Dietz Syndrome Shows Elevated Susceptibility to Periodontitis via Alterations in Transforming Growth Factor-Beta Signaling2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibitory effects of PLAP-1/asporin on periodontal ligament cells2014

Author(s)

Journal Title

DOI

Kajikawa Tetsuhiro 梶川哲宏

KAJIKAWA TETSUHIRO 梶川哲宏

KAJIKAWA Tetsuhiro 梶川哲宏

[Presentation] 白血球接着不全症I型(LAD-I)関連歯周炎の発症メカニズムと治療法2022