Koyama Akihide 小山哲秀

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KOYAMA Akihide 小山哲秀

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Researcher Number	90622209
Other IDs
Affiliation (Current)	2025: 新潟大学, 医歯学系, 助教
Affiliation (based on the past Project Information) *help	2017 – 2025: 新潟大学, 医歯学系, 助教 2016: 新潟大学, 脳研究所, 特任助教 2014 – 2015: 新潟大学, 研究推進機構, 助教 2013: 新潟大学, 脳研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 45060:Applied anthropology-related / Basic Section 58010:Medical management and medical sociology-related / Basic Section 58040:Forensics medicine-related Except Principal Investigator Neurology / Medium-sized Section 58:Society medicine, nursing, and related fields
Keywords	Principal Investigator デジタルPCR / 絶対定量 / DNA / 品質管理 / 迅速検査 / リアルタイムPCR / 移動式PCR検査 / ダイレクトPCR / 災害 / 移動式PCR … More / 災害医療 / 新型コロナウイルス / オンサイト検査 / 感染症検査 / 定量PCR / 骨 / 歯 / 水道水 / 認知症 / 高齢社会 / 身元特定法 / 身元特定 / 毛髪 / 安定同位体 / 法医学 / 安定同位体比 / 身元推定 … More Except Principal Investigator エコヘルス / 顧みられない熱帯病 / 環境DNA / 感染ダイナミクス / 住血吸虫病 / 蛋白質 / HTRA1 / CARASIL / タンパク質 / 痴呆 / 病理学 / 循環器 / 脳神経疾患 / 脳小血管病 / 脳血管障害 / 認知症 / 脳小血管 / 神経病帯 / 脳循環 / 神経病態 / 脳血管 Less

法医人類学におけるシン・DNA品質管理法の確立Principal Investigator
- Principal Investigator
  
  小山哲秀
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 45060:Applied anthropology-related
- Research Institution
  Niigata University
Elucidation of Schistosoma japonicum ecological dynamics in localities with different epidemiological status using novel high-sensitivity environmental approaches
- Principal Investigator
  
  オオタケサトウマルセロ
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Niigata University of Pharmacy and Medical and Life Sciences
Establishment of on-site temporary PCR testing methods.Principal Investigator
- Principal Investigator
  
  KOYAMA Akihide
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Niigata University
Development of geographical area prediction model based on human hair and tap water stable isotopePrincipal Investigator
- Principal Investigator
  
  KOYAMA AKIHIDE
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 58040:Forensics medicine-related
- Research Institution
  Niigata University
Strategies for overcoming vascular dementia focusing on dynamic functions of cerebral small vessels.
- Principal Investigator
  
  Onodera Osamu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Approach to cerebral small vessel disease: lesson from CARASIL.
- Principal Investigator
  
  Onodera Osamu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Niigata University

All 2023 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] Distinct molecular mechanisms of HTRA1 mutants in manifesting heterozygotes with CARASIL.2016
- Author(s)
  Nozaki H, Kato T, Nihonmatsu M, Saito Y, Mizuta I, Noda T, Koike R, Miyazaki K, Kaito M, Ito S, Makino M, Koyama A, Shiga A, Uemura M, Sekine Y, Murakami A, Moritani S, Hara K, Yokoseki A, Kuwano R, Endo N, Momotsu T, Yoshida M, Nishizawa M, Mizuno T, Onodera O
- Journal Title
  
  Neurology
  
  Volume: 86 Issue: 21 Pages: 1-10
- DOI
  10.1212/wnl.0000000000002694
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461276, KAKENHI-PLANNED-26117006, KAKENHI-PROJECT-16H02656
[Journal Article] Distinct molecular mechanisms of HTRA1 mutants in manifesting heterozygotes with CARASIL2016
- Author(s)
  Nozaki H, Kato T, Nihonmatsu M, Saito Y, Mizuta I, Noda T, Koike R, Miyazaki K, Kaito M, Ito S, Makino M, Koyama A, Shiga A, Uemura M, Sekine Y, Murakami A, Moritani S, Hara K, Yokoseki A, Kuwano R, Endo N, Momotsu T, Yoshida M, Nishizawa M, Mizuno T, Onodera O.
- Journal Title
  
  Neurology
  
  Volume: 未定
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293200
[Journal Article] Emerging molecular mechanism for cerebral small vessel disease: Lessons from hereditary small vessel disease2015
- Author(s)
  Onodera, O., Sekine, Y., Kato, T., Koyama, A., Nozaki, H. and Nishizawa, M
- Journal Title
  
  Neurology and Clinical Neuroscience
  
  Volume: 1 Issue: 1 Pages: 7-13
- DOI
  10.1111/ncn3.134
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293200
[Journal Article] Haploinsufficiency of CSF-1R and clinicopathological characterization in patients with HDLS.2014
- Author(s)
  Konno T, Tada M, Tada M, Koyama A, Nozaki H, Harigaya Y, Nishimiya J, Matsunaga A, Yoshikura N, Ishihara K, Arakawa M, Isami A, Okazaki K, Yokoo H, Ihoh K, Yoneda M, Kawamura M, Inuzuka T, Takahashi H, Nishizawa M, Onodera O, Kakita A, Ikeuchi T
- Journal Title
  
  Neurology
  
  Volume: 82 Issue: 2 Pages: 139-148
- DOI
  10.1212/wnl.0000000000000046
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22129004, KAKENHI-PUBLICLY-24111517, KAKENHI-PROJECT-25293200, KAKENHI-PROJECT-25430048
[Presentation] 災害時に即応可能な迅速PCR検査の確立2023
- Author(s)
  小山哲秀, 和泉邦彦, 高塚尚和, 高橋昌
- Organizer
  第28回日本災害医学学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K17302
[Presentation] The prevalence estimates of HTRA1-associated cerebral small vessel disease2017
- Author(s)
  Hiroaki Nozaki, Akihide Koyama, Masahiro Uemura, Taisuke Kato, Osamu Onodera
- Organizer
  The 8th Korea-Japan Joint Stroke Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] RVCL関連変異の細胞内局在についての検討．2017
- Author(s)
  笠原杏子, 加藤泰介, 野崎洋明, 小山哲秀, 小野寺理．
- Organizer
  第36回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] Molecular analysis of mutant high-temperature requirement serine protease A1 identified in patients with familial cerebral small vessel disease2017
- Author(s)
  Uemura M, Nozaki H, Kato T, Koyama A, Onodera O
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] 家族性脳小血管病患者で同定された変異型HTRA1蛋白質のプロテアーゼ活性解析2017
- Author(s)
  上村昌寛, 野崎洋明, 加藤泰介, 小山哲秀, 小野寺理
- Organizer
  第47回新潟神経学夏季セミナー
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] Protease activity analysis of mutant high-temperature requirement serine protease A1 identified in patients with familial cerebral small vessel disease2017
- Author(s)
  Uemura M, Nozaki H, Kato T, Koyama A, Onodera O
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] 家族性脳小血管病患者で報告された変異型HTRA1蛋白質の機能解析2017
- Author(s)
  上村昌寛, 野崎洋明, 加藤泰介, 小山哲秀, 小野寺理
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] Molecular analysis of mutant high-temperature requirement serine protease A1 identified in patients with familial cerebral small vessel disease2017
- Author(s)
  Uemura M, Nozaki H, Kato T, Koyama A, Onodera O
- Organizer
  Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] The prevalence estimates of HTRA1-associated cerebral small vessel disease2017
- Author(s)
  Hiroaki Nozaki, Akihide Koyama, Masahiro Uemura, Taisuke Kato, Osamu Onodera
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02656
[Presentation] Dominant Negative HTRA1 Mutations in Cerebral Small Vessel Disease.2015
- Author(s)
  Nozaki H, Kato T, Nihonmatsu M, Saito Y, Mizuta I, Noda T, Koike R, Miyazaki K, Kaito M, Ito S, Makino M, Koyama A, Shiga A, Uemura M, Sekine Y, Murakami A, Moritani S, Hara K, Yokoseki A, Kuwano R, Endo N, Momotsu T, Yoshida M, Nishizawa M, Mizuno T, Onodera O.
- Organizer
  9th International Congress on Vascular Dementia; ICVD 2015
- Place of Presentation
  Ljubljana, Slovenija
- Year and Date
  2015-10-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293200

1. Onodera Osamu (20303167)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
2. TOYOSHIMA Yasuko (20334675)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. SATO Toshiya (90359703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 加藤泰介 (30598496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
5. 野崎洋明 (20547567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. オオタケサトウマルセロ (50771896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 迫康仁 (40312459)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. サトウ恵 (70601813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 高橋エミリー (70747138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MIZUNO Toshiki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. MIZUTA Ikuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 柿田明美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Koyama Akihide 小山 哲秀

KOYAMA Akihide 小山 哲秀

Research Projects

Research Products

Co-Researchers

法医人類学におけるシン・DNA品質管理法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of Schistosoma japonicum ecological dynamics in localities with different epidemiological status using novel high-sensitivity environmental approaches

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of on-site temporary PCR testing methods.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of geographical area prediction model based on human hair and tap water stable isotopePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Strategies for overcoming vascular dementia focusing on dynamic functions of cerebral small vessels.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Approach to cerebral small vessel disease: lesson from CARASIL.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Distinct molecular mechanisms of HTRA1 mutants in manifesting heterozygotes with CARASIL.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distinct molecular mechanisms of HTRA1 mutants in manifesting heterozygotes with CARASIL2016

Author(s)

Journal Title

Data Source

[Journal Article] Emerging molecular mechanism for cerebral small vessel disease: Lessons from hereditary small vessel disease2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Haploinsufficiency of CSF-1R and clinicopathological characterization in patients with HDLS.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] 災害時に即応可能な迅速PCR検査の確立2023

Author(s)

Organizer

Data Source

[Presentation] The prevalence estimates of HTRA1-associated cerebral small vessel disease2017

Author(s)

Organizer

Data Source

[Presentation] RVCL関連変異の細胞内局在についての検討．2017

Author(s)

Organizer

Data Source

[Presentation] Molecular analysis of mutant high-temperature requirement serine protease A1 identified in patients with familial cerebral small vessel disease2017

Author(s)

Organizer

Data Source

[Presentation] 家族性脳小血管病患者で同定された変異型HTRA1蛋白質のプロテアーゼ活性解析2017

Author(s)

Organizer

Data Source

Koyama Akihide 小山哲秀

KOYAMA Akihide 小山哲秀