Nishi Mayuko 西真由子

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NISHI Mayuko 西真由子

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Researcher Number	90635343
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立感染症研究所バイオインフォマティクス・オミクス研究部, 主任研究員
Affiliation (based on the past Project Information) *help	2023 – 2024: 国立感染症研究所, ウイルス第三部, 主任研究官 2020 – 2022: 横浜市立大学, 医学部, 助教 2020: 横浜市立大学, 医学研究科, 助教 2018 – 2019: 横浜市立大学, 医学研究科, 特任助教 2013 – 2014: 横浜市立大学, 医学(系)研究科(研究院), 特任助教
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Basic Section 50010:Tumor biology-related / Tumor biology
Keywords	Principal Investigator 脳腫瘍 / 悪性リンパ腫 / PCNSL / 光制御 / 麻疹ウイルス / 腫瘍溶解性ウイルス / ペリサイト / 細胞間相互作用 / 微小環境 / 腫瘍免疫 … More / ウイルス / 細胞老化 / 癌抑制遺伝子 / リン酸化 / 癌幹細胞 Less

Creation and verification of a therapeutic strategy for PCNSL using photoregulated measles virusPrincipal Investigator
- Principal Investigator
  
  西真由子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  National Institute of Infectious Diseases
Elucidating the nature of primary central nervous system lymphoma based on the microenvironment and exploring new therapeutic targetsPrincipal Investigator
- Principal Investigator
  
  Nishi Mayuko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  National Institute of Infectious Diseases
  Yokohama City University
Engineering of T cells with customized cancer therapeutic programs using synthetic notch receptor.Principal Investigator
- Principal Investigator
  
  NISHI Mayuko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Yokohama City University
A study for molecular mechanism of the Cdk-Pin1 axis in cancer stem cellPrincipal Investigator
- Principal Investigator
  
  NISHI Mayuko
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Yokohama City University

All 2023 2022 2021 2020 2019 2018 2015 2014 2013

All Journal Article Presentation

[Journal Article] Development of a contacting transwell co-culture system for the in vitro propagation of primary central nervous system lymphoma2023
- Author(s)
  Nishi M, Tateishi K, Sundararaj JS, Ino Y, Nakai Y, Hatayama Y, Yamaoka Y, Mihana Y, Miyakawa K, Kimura H, Kimura Y, Yamamoto T, Ryo A.
- Journal Title
  
  Front Cell Dev Biol
  
  Volume: 11 Pages: 15768-15768
- DOI
  10.3389/fcell.2023.1275519
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09210, KAKENHI-PROJECT-21K09106, KAKENHI-PROJECT-23K27419, KAKENHI-PROJECT-23K27641
[Journal Article] Rapid quantitative screening assay for SARS-CoV-2 neutralizing antibodies using HiBiT-tagged virus-like particles2021
- Author(s)
  Miyakawa K, Jeremiah SS, Ohtake N, Matsunaga S, Yamaoka Y, Nishi M, Morita T, Saji R, Nishii M, Kimura H, Hasegawa H, Takeuchi I, Ryo A.
- Journal Title
  
  J Mol Cell Biol.
  
  Volume: 12 Issue: 12 Pages: 987-990
- DOI
  10.1093/jmcb/mjaa047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09000
[Journal Article] Zika virus protease induces caspase-independent pyroptotic cell death by directly cleaving gasdermin D2021
- Author(s)
  Yamaoka Y, Matsunaga S, Jeremiah SS, Nishi M, Miyakawa K, Morita T, Khatun H, Shimizu H, Okabe N, Kimura H, Hasegawa H, Ryo A.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 534 Pages: 666-671
- DOI
  10.1016/j.bbrc.2020.11.023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09000
[Journal Article] Carbonic anhydrase 13 suppresses bone metastasis in breast cancer2021
- Author(s)
  Yogosawa Satomi、Nakayama Jun、Nishi Mayuko、Ryo Akihide、Yoshida Kiyotsugu
- Journal Title
  
  Cancer Treatment and Research Communications
  
  Volume: 27 Pages: 100332-100332
- DOI
  10.1016/j.ctarc.2021.100332
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03519, KAKENHI-PROJECT-17K08672, KAKENHI-PROJECT-18K09000, KAKENHI-PROJECT-18K19484
[Journal Article] A Hyperactive RelA/p65-Hexokinase 2 Signaling Axis Drives Primary Central Nervous System Lymphoma2020
- Author(s)
  Tateishi Kensuke、Miyake Yohei、Kawazu Masahito、Sasaki Nobuyoshi、Nakamura Taishi、Sasame Jo、Yoshii Yukie、Ueno Toshihide、Miyake Akio、Matsushita Yuko、Shiba Norio、Udaka Naoko、Ohki Kentaro、Fink Alexandria L.、Tummala Shilpa S.、Natsumeda Manabu、Miller Julie J.、Fujii Yukihiko、et al
- Journal Title
  
  Cancer Research
  
  Volume: 80 Issue: 23 Pages: 5330-5343
- DOI
  10.1158/0008-5472.can-20-2425
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10888, KAKENHI-PROJECT-19K08350, KAKENHI-PROJECT-19K09476, KAKENHI-PROJECT-19K09488, KAKENHI-PROJECT-19K18398, KAKENHI-PROJECT-17K10057, KAKENHI-PROJECT-18K07320, KAKENHI-PROJECT-18K08950, KAKENHI-PROJECT-18K09000, KAKENHI-PROJECT-19H03774
[Journal Article] Development of Monoclonal Antibodies and Antigen-Capture ELISA for Human Parechovirus Type 3.2020
- Author(s)
  Goto K, Yamaoka Y, Khatun H, Miyakawa K, Nishi M, Nagata N, Yanaoka T, Kimura H, Ryo A.
- Journal Title
  
  Microorganisms.
  
  Volume: 8 Issue: 9 Pages: 1437-1437
- DOI
  10.3390/microorganisms8091437
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09000
[Journal Article] Prolyl Isomerase Pin1 Regulates the Stability of Hepatitis B Virus Core Protein.2020
- Author(s)
  Nishi M, Miyakawa K, Matsunaga S, Khatun H, Yamaoka Y, Watashi K, Sugiyama M, Kimura H, Wakita T, Ryo A.
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 8 Pages: 26-26
- DOI
  10.3389/fcell.2020.00026
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09000, KAKENHI-PROJECT-17H04085
[Journal Article] PIM kinases facilitate lentiviral evasion from SAMHD1 restriction via Vpx phosphorylation2019
- Author(s)
  Miyakawa Kei、Matsunaga Satoko、Yokoyama Masaru、Nomaguchi Masako、Kimura Yayoi、Nishi Mayuko、Kimura Hirokazu、Sato Hironori、Hirano Hisashi、Tamura Tomohiko、Akari Hirofumi、Miura Tomoyuki、Adachi Akio、Sawasaki Tatsuya、Yamamoto Naoki、Ryo Akihide
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1844-1844
- DOI
  10.1038/s41467-019-09867-7
- NAID
  120006949469
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04729, KAKENHI-PROJECT-16H05198, KAKENHI-PROJECT-16H05230, KAKENHI-PROJECT-16K08814, KAKENHI-PROJECT-18K09000, KAKENHI-PROJECT-19K07594, KAKENHI-PLANNED-16H06579, KAKENHI-PROJECT-19H03218, KAKENHI-PROJECT-17K08860, KAKENHI-PROJECT-19H03146, KAKENHI-PROJECT-19H03774
[Journal Article] TROY expression is associated with pathological stage and poor prognosis in patients treated with radical cystectomy.2019
- Author(s)
  Nomura M, Matsumoto K, Shimizu Y, Ikeda M, Amano N, Nishi M, Ryo A, Nagashio R, Sato Y, Iwamura M.
- Journal Title
  
  Cancer Biomark.
  
  Volume: 24(1) Issue: 1 Pages: 91-96
- DOI
  10.3233/cbm-181911
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09000, KAKENHI-PROJECT-18K09206
[Journal Article] PI3K/AKT/mTOR pathway alterations promote malignant progression and xenograft formation in oligodendroglial tumors.2019
- Author(s)
  Tateishi K, Nakamura T, Juratli TA, Williams EA, Matsushita Y, Miyake S, Nishi M, Miller JJ, Ryo A, Yamanaka S, Curry WT, Dias-Santagata D, Yamamoto T, Ichimura K, Batchelor T, Chi AS, Iafrate AJ, Wakimoto H, Cahill DP, et al.
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 印刷中 Issue: 14 Pages: 4375-4387
- DOI
  10.1158/1078-0432.ccr-18-4144
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09000, KAKENHI-PROJECT-19K09488, KAKENHI-PROJECT-17K10903, KAKENHI-PROJECT-19H03774
[Journal Article] A novel inhibitor of tumorspheres reveals the activation of the serine biosynthetic pathway upon mitochondrial inhibition.2019
- Author(s)
  Subedi A, Muroi M, Futamura Y, Kawamura T, Aono H, Nishi M, Ryo A, Watanabe N, Osada H.
- Journal Title
  
  FEBS Lett.
  
  Volume: 593 Issue: 8 Pages: 763-776
- DOI
  10.1002/1873-3468.13361
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01970, KAKENHI-PROJECT-17K07783, KAKENHI-PLANNED-17H06412, KAKENHI-PROJECT-18H03945, KAKENHI-PROJECT-18K09000, KAKENHI-PUBLICLY-19H05302
[Journal Article] Lnc RNA H19 is associated with poor prognosis in breast cancer patients and promotes cancer stemness.2018
- Author(s)
  Shima H, Kida K, Adachi S, Yamada A, Sugae S, Narui K, Miyagi Y, Nishi M, Ryo A, Murata S, Taniguchi H, Ichikawa Y, Ishikawa T, Endo I.
- Journal Title
  
  Breast Cancer Res Treat.
  
  Volume: 170(3) Issue: 3 Pages: 507-516
- DOI
  10.1007/s10549-018-4793-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09000, KAKENHI-PROJECT-16K19055
[Journal Article] Development of an induced cancer stem cell model for drug discovery.2015
- Author(s)
  Nishi M, Ryo A.
- Journal Title
  
  Cancer Cell & Microenvironment
  
  Volume: 1:e461
- DOI
  10.14800/ccm.461
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25830087
[Journal Article] Induced cancer stem-like cells as a model for biological screening and discovery of agents targeting phenotypic traits of cancer stem cell.2014
- Author(s)
  Nishi M, Akutsu H, Kudoh A, Kimura H, Yamamoto N, Umezawa A, Lee SW, Ryo A.
- Journal Title
  
  Oncotarget
  
  Volume: 5(18) Pages: 8665-8680
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25830087
[Presentation] 血管周皮細胞と共培養された原発性CNSリンパ腫（PCNSL）の細胞生存と増殖におけるプロリルイソメラーゼPin1の役割2022
- Author(s)
  西真由子,立石健祐, 中居佑介, 巳鼻佑作, 木村弥生, 山本哲哉, 梁　明秀
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K09106
[Presentation] ビトリゲル膜を介した両面培養による中枢神経系原発悪性リンパ腫細胞と脳血管周皮細胞との相互作用解析2019
- Author(s)
  西真由子,立石健祐, 畑山靖佳, 山岡悠太郎, 山本哲哉, 梁　明秀
- Organizer
  第42回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K09000
[Presentation] Induction of cells with cancer stem cell properties from p53-deficient somatic cells2013
- Author(s)
  Mayuko Nishi, Akihide Ryo
- Organizer
  2013 American Association for Cancer Research Meeting, Molecular Targets and Cancer Therapeutics
- Place of Presentation
  Hynes Convention Center Boston, MA, USA.
- Data Source
  KAKENHI-PROJECT-25830087
[Presentation] In vitro generation of cells with cancer stem-cell properties from human prostate epithelial cells2013
- Author(s)
  Mayuko Nishi, Yukiko Watanabe, Akihide Ryo
- Organizer
  第72回　日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Data Source
  KAKENHI-PROJECT-25830087

1. 田原舞乃 (10572109)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 立石健祐 (00512055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. FUJII Yukihiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. FUTAMURA Yushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 澤崎達也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 吉田清嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishi Mayuko 西 真由子

NISHI Mayuko 西 真由子

Research Projects

Research Products

Co-Researchers

Creation and verification of a therapeutic strategy for PCNSL using photoregulated measles virusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating the nature of primary central nervous system lymphoma based on the microenvironment and exploring new therapeutic targetsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Engineering of T cells with customized cancer therapeutic programs using synthetic notch receptor.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A study for molecular mechanism of the Cdk-Pin1 axis in cancer stem cellPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Development of a contacting transwell co-culture system for the in vitro propagation of primary central nervous system lymphoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rapid quantitative screening assay for SARS-CoV-2 neutralizing antibodies using HiBiT-tagged virus-like particles2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Zika virus protease induces caspase-independent pyroptotic cell death by directly cleaving gasdermin D2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Carbonic anhydrase 13 suppresses bone metastasis in breast cancer2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Hyperactive RelA/p65-Hexokinase 2 Signaling Axis Drives Primary Central Nervous System Lymphoma2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of Monoclonal Antibodies and Antigen-Capture ELISA for Human Parechovirus Type 3.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prolyl Isomerase Pin1 Regulates the Stability of Hepatitis B Virus Core Protein.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PIM kinases facilitate lentiviral evasion from SAMHD1 restriction via Vpx phosphorylation2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] TROY expression is associated with pathological stage and poor prognosis in patients treated with radical cystectomy.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PI3K/AKT/mTOR pathway alterations promote malignant progression and xenograft formation in oligodendroglial tumors.2019

Author(s)

Journal Title

DOI

Data Source

Nishi Mayuko 西真由子

NISHI Mayuko 西真由子