Fujikawa Yuuta 藤川雄太

… Alternative Names

藤川雄太フジカワユウタ

Yuuta Fujikawa 藤川雄太

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Researcher Number	90645144
Other IDs
Affiliation (Current)	2025: 東京薬科大学, 生命科学部, 准教授
Affiliation (based on the past Project Information) *help	2023: 東京薬科大学, 生命科学部, 准教授 2021: 東京薬科大学, 生命科学部, 准教授 2018 – 2021: 東京薬科大学, 生命科学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 37030:Chemical biology-related Except Principal Investigator Basic Section 43030:Functional biochemistry-related
Keywords	Principal Investigator イメージング / レドックス / 蛍光プローブ / ケミカルバイオロジー / 薬物代謝酵素 / 光誘起電子移動 / 蛍光イメージング / 酵素 / GSTP / ナフタルイミド / GSTP1 / グルタチオン / GST … More Except Principal Investigator … More アシルトランスフェラーゼ / ドーパミン / リン脂質 Less

分子動態に着目した特異的GSTP1活性検出プローブの開発Principal Investigator
- Principal Investigator
  
  藤川雄太
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Studies on novel fatty acid transferases that synthesize novel endogenous cancer metabolites derived from phospholipids
- Principal Investigator
  
  前本佑樹
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Development of GSTP1 fluorescent probes for the elucidation of the function of GSTP1 in cancer cells.Principal Investigator
- Principal Investigator
  
  Yuuta Fujikawa
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Tokyo University of Pharmacy and Life Science

All 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathioneS-transferase Noppera-bo in Aedes aegypti2022
- Author(s)
  Inaba,K.,Ebihara,K.,Senda,M.,Yoshino,R.,Sakuma,C.,Koiwai,K.,Takaya,D.,Watanabe,C.,Watanabe,A.,Kawashima,Y.,Fukuzawa,K.,Imamura,R.,Kojima,H.,Okabe,T.,Uemura,N.,Kasai,S.,Kanuka,H.,Nishimura,T.,Watanabe,K.,Inoue,H.,Fujikawa,Y.,Honma,T.,Hirokawa,T.,Senda,T.,Niwa,R.
- Journal Title
  
  BMC Biology
  
  Volume: 20 Issue: 1 Pages: 43-43
- DOI
  10.1186/s12915-022-01233-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05362
[Journal Article] Non-steroidal inhibitors of <i>Drosophila melanogaster</i> steroidogenic glutathione <i>S</i>-transferase Noppera-bo2021
- Author(s)
  Koiwai, K., Morohashi, K., Inaba, K., Ebihara, K., Kojima, H., Okabe, T., Yoshino, R., Hirokawa, T., Nampo, T., Fujikawa, Y., Inoue, H., Yumoto, F., Senda, T., Niwa, R.
- Journal Title
  
  Journal of Pesticide Science
  
  Volume: 46 Issue: 1 Pages: 75-87
- DOI
  10.1584/jpestics.D20-072
- NAID
  130007992097
- ISSN
  1348-589X, 1349-0923
- Year and Date
  2021-02-20
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05362
[Journal Article] The plant-derived triterpenoid, cucurbitacin B, but not cucurbitacin E, inhibits the developmental transition associated with ecdysone biosynthesis in Drosophila melanogaster2021
- Author(s)
  Miwako Toyofuku, Daiki Fujinaga, Kazue Inaba, Tomoki Funahashi, Yuuta Fujikawa, Hideshi Inoue, Hiroshi Kataoka, Ryusuke Niwa, Hajime Ono
- Journal Title
  
  Journal of Insect Physiology
  
  Volume: 134 Pages: 104294-104294
- DOI
  10.1016/j.jinsphys.2021.104294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02214, KAKENHI-PROJECT-18K05362
[Journal Article] An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo.2020
- Author(s)
  Koiwai K, Inaba K, Morohashi K, Enya S, Arai R, Kojima H, Okabe T, Fujikawa Y, Inoue H, Yoshino R, Hirokawa T, Kato K, Fukuzawa K, Shimada-Niwa Y, Nakamura A, Yumoto F, Senda T, Niwa R.
- Journal Title
  
  J Biol Chem.
  
  Volume: - Issue: 20 Pages: 7154-7167
- DOI
  10.1074/jbc.ra119.011463
- NAID
  120007165465
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06264, KAKENHI-PROJECT-18K19163, KAKENHI-PROJECT-18K05362
[Journal Article] Convenient synthesis of regioisomerically pure 5- and 6-functionalized xanthene dyes via SNAr reaction and comparison of their reactivity towards click reaction.2020
- Author(s)
  Mori, M., Fujikawa, Y., Inoue, H.
- Journal Title
  
  Tetrahedron
  
  Volume: 76(15) Issue: 15 Pages: 131087-131087
- DOI
  10.1016/j.tet.2020.131087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05362
[Journal Article] The evolutionarily conserved deubiquitinase UBH1/UCH-L1 augments DAF7/TGF-β signaling, inhibits dauer larva formation, and enhances lung tumorigenesis.2020
- Author(s)
  Nagata A, Itoh F, Sasho A, Sugita K, Suzuki R, Hinata H, Shimoda Y, Suzuki E, Maemoto Y, Inagawa T, Fujikawa Y, Ikeda E, Fujii C, Inoue H.
- Journal Title
  
  J. Biol. Chem
  
  Volume: in press Issue: 27 Pages: 9105-9120
- DOI
  10.1074/jbc.ra119.011222
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08794, KAKENHI-PROJECT-18K05362
[Journal Article] A highly selective　fluorogenic　substrate　for　imaging　glutathione　S-transferase　P1:　development,　cellular　applicability to epigenetic studies2019
- Author(s)
  Mori, M., Fujikawa, Y., Kikkawa, M., Shino, M., Sawane, M., Sato, S. and Inoue, H.
- Journal Title
  
  Chemical communications
  
  Volume: 55 Issue: 56 Pages: 8122-8125
- DOI
  10.1039/c9cc03064f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05362
[Journal Article] 4-Bromo-1,8-naphthalimide derivatives as fluorogenic substrates for live cell imaging of glutathione S-transferase (GST) activity.2019
- Author(s)
  Fujikawa, Y., Terakado, K., Nampo, T., Mori, M., and Inoue, H.
- Journal Title
  
  Talanta
  
  Volume: 204 Pages: 633-640
- DOI
  10.1016/j.talanta.2019.06.059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05362
[Journal Article] Exploration of Insect Growth Regulators Targeting Noppera-bo, an Enzyme Involved in Ecdysteroid Biosynthesis2018
- Author(s)
  藤川雄太, 井上英史
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 138 Issue: 8 Pages: 1043-1048
- DOI
  10.1248/yakushi.17-00211-3
- NAID
  130007429055
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2018-08-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] シンポジウム「薬学留学が拓く多様性溢れる未来」2022
- Author(s)
  藤川雄太、中山淳
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] ミトコンドリア H2O2 産生系によって誘導されるマイトファジーの評価2021
- Author(s)
  池谷知美、藤川雄太、渡邉栄太、井上英史
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] 海外留学のススメ～海外での挑戦から考えること～2020
- Author(s)
  藤川雄太、中山淳
- Organizer
  日本薬学会第100年会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] D-アミノ酸オキシダーゼを用いたミトコンドリア H 2O 2 産生系の構築とその応用2020
- Author(s)
  池谷知美、藤川雄太、熊倉夏希、井上英史
- Organizer
  日本薬学会第100年会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] プロドラッグ化に依らない細胞膜透過型GSTP１活性検出蛍光プローブの開発とその応用2020
- Author(s)
  渡邉幸大、藤川雄太、森雅矢、坂田萌、井上英史
- Organizer
  日本薬学会第100年会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] GSTP1選択的活性検出蛍光プローブの開発とその応用2020
- Author(s)
  森雅矢，藤川雄太，井上英史
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] ミトコンドリア H 2O 2 産生系を用いた PINK1/Parkin を介したマイトファジーへの H 2O 2 の影響の評価2020
- Author(s)
  池谷知美, 藤川雄太, 熊倉夏希, 井上英史
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] D-アミノ酸／D-アミノ酸オキシダーゼを利用したミトコンドリアH 2O 2産生系およびH 2O 2がミトコンドリアに及ぼす影響の評価2020
- Author(s)
  池谷知美、熊倉夏希、藤川雄太、井上英史
- Organizer
  第12回大学コンソーシアム八王子学生発表会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] 化学で攻める新しい創薬のカタチ2020
- Author(s)
  藤川雄太, 小松徹*
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] ミトコンドリア局在型H2O2産生系の構築と応用2019
- Author(s)
  藤川雄太、熊倉夏希、池谷知美、青山芙由子、田邨瑞希、井上英史
- Organizer
  第８回医薬工３大学包括連携推進シンポジウム
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] GSTP1選択的活性検出蛍光プローブの開発とその応用2019
- Author(s)
  森雅矢、藤川雄太、井上英史
- Organizer
  第11回大学コンソーシアム八王子学生発表会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] D-アミノ酸酸化酵素/D-アミノ酸ペアによるミトコンドリア局在型H2O2産生系の構築とその応用2019
- Author(s)
  藤川雄太，熊倉夏希，青山芙由子，田村瑞希，井上英史
- Organizer
  第72回日本酸化ストレス学会学術集会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] 脱ユビキチン化酵素UCH-L1は低酸素条件下でTGF-βシグナルを増強する2019
- Author(s)
  永田麻未、佐粧彩海、鈴木理子、鈴木映里、下田裕太、藤川雄太、渡部琢也、伊東史子、井上英史
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] 新規GSTP1選択的活性検出蛍光プローブの開発2019
- Author(s)
  森雅矢、藤川雄太、井上英史
- Organizer
  第８回医薬工３大学包括連携推進シンポジウム
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] 高い選択性を持つ細胞膜透過型GSTP1活性検出蛍光プローブの開発2019
- Author(s)
  渡邉幸大、藤川雄太、森雅矢、井上英史
- Organizer
  第63回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] 蛍光プローブを用いたスクリーニング系に基づく生細胞 GSTP1 選択的阻害剤の開発2019
- Author(s)
  南保泰希, 藤川雄太, 小島宏達, 岡部隆義, 長野哲雄, 井上英史
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] ドイツでのポスドクとしての期間を振り返る2019
- Author(s)
  藤川雄太
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] 赤色酵母由来D-アミノ酸オキシダーゼを利用したミトコンドリアH2O2産生系の構築およびその応用2019
- Author(s)
  池谷知美、熊倉夏希、藤川雄太、井上英史
- Organizer
  第11回大学コンソーシアム八王子学生発表会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] GSTP1選択的活性検出蛍光プローブの開発とがん細胞イメージング2019
- Author(s)
  森雅矢、藤川雄太、井上英史
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] 蛍光プローブを利用したスクリーニング系に基づく生細胞 GSTP1 選択的阻害剤の開発2019
- Author(s)
  藤川雄太，南保泰希，今村理世，岡部隆義，小祝孝太郎，千田拓哉，井上英史
- Organizer
  第37回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] 脱ユビキチン化酵素UCH-L1はTGF-bシグナルを増強し、肺がん形成に関与する2019
- Author(s)
  永田麻未、伊東史子、藤川雄太、井上英史
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] ユビキチン C 末端加水分解酵素 UCH-L1 は Smad2 を介して TGF-β シグナルを正に制御する2018
- Author(s)
  永田麻未, 佐粧彩海, 鈴木理子, 鈴木映里, 下田裕太, 藤川雄太, 渡部琢也, 伊東史子, 井上英史
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] Development of GSTP1 fluorogenic substrates for cancer cell imaging2018
- Author(s)
  森雅矢，藤川雄太，井上英史
- Organizer
  第181回東京医科大学医学会総会
- Data Source
  KAKENHI-PROJECT-18K05362
[Presentation] がん細胞の多色イメージングを目指した新規GSTP1活性検出蛍光プローブの開発2018
- Author(s)
  森雅矢、藤川雄太、井上英史
- Organizer
  日本ケミカルバイオロジー学会　第13回年会
- Data Source
  KAKENHI-PROJECT-18K05362

1. 前本佑樹 (90742619)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. ONO Hajime

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 千田俊哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 片岡宏志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 伊東史子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujikawa Yuuta 藤川 雄太

藤川 雄太 フジカワ ユウタ

Yuuta Fujikawa 藤川 雄太

Research Projects

Research Products

Co-Researchers

分子動態に着目した特異的GSTP1活性検出プローブの開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies on novel fatty acid transferases that synthesize novel endogenous cancer metabolites derived from phospholipids

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of GSTP1 fluorescent probes for the elucidation of the function of GSTP1 in cancer cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathioneS-transferase Noppera-bo in Aedes aegypti2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Non-steroidal inhibitors of <i>Drosophila melanogaster</i> steroidogenic glutathione <i>S</i>-transferase Noppera-bo2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] The plant-derived triterpenoid, cucurbitacin B, but not cucurbitacin E, inhibits the developmental transition associated with ecdysone biosynthesis in Drosophila melanogaster2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo.2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Convenient synthesis of regioisomerically pure 5- and 6-functionalized xanthene dyes via SNAr reaction and comparison of their reactivity towards click reaction.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The evolutionarily conserved deubiquitinase UBH1/UCH-L1 augments DAF7/TGF-β signaling, inhibits dauer larva formation, and enhances lung tumorigenesis.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A highly selective fluorogenic substrate for imaging glutathione S-transferase P1: development, cellular applicability to epigenetic studies2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 4-Bromo-1,8-naphthalimide derivatives as fluorogenic substrates for live cell imaging of glutathione S-transferase (GST) activity.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Exploration of Insect Growth Regulators Targeting Noppera-bo, an Enzyme Involved in Ecdysteroid Biosynthesis2018

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Presentation] シンポジウム「薬学留学が拓く多様性溢れる未来」2022

Author(s)

Fujikawa Yuuta 藤川雄太

藤川雄太フジカワユウタ

Yuuta Fujikawa 藤川雄太

[Journal Article] A highly selective　fluorogenic　substrate　for　imaging　glutathione　S-transferase　P1:　development,　cellular　applicability to epigenetic studies2019