Kamatani Takashi 鎌谷高志

… Alternative Names

Takashi Kamatani 鎌谷高志

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Researcher Number	90645764
Other IDs
Affiliation (Current)	2026: 公益財団法人がん研究会, がん研究所情報医科学プロジェクト, プロジェクトリーダー 2026: 東京科学大学, 総合研究院, 講師
Affiliation (based on the past Project Information) *help	2024 – 2025: 東京科学大学, 総合研究院, 講師 2022 – 2024: 東京医科歯科大学, M&Dデータ科学センター, 講師 2020 – 2021: 東京大学, 大学院理学系研究科(理学部), 特任助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Medium-sized Section 62:Applied informatics and related fields Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 54030:Infectious disease medicine-related / Basic Section 56040:Obstetrics and gynecology-related
Keywords	Principal Investigator がん免疫 / 深層学習 / １細胞RNA-seq / CD8陽性T細胞 / 腫瘍微小環境 / 多領域シーケンス / 尿路上皮がん / サブクローン / 多領域解析 / 免疫チェックポイント阻害薬 … More / マルチオミックス / がん免疫療法 / RNA-seq / 粘液型脂肪肉腫 / 南部肉腫 / 予後予測 / WES / 病理画像 / RNA / 軟部肉腫 / 遺伝子発現 / 脂肪肉腫 … More Except Principal Investigator 免疫チェックポイント阻害薬 / トラジェクトリー / 軌跡地図 / 間質 / がん免疫治療 / 環境因子 / ソフトウェア医療機器 / 個別化治療 / ピークフロー / 気管支喘息 / プロテオミクス解析 / ムチン / 肺MAC症 / 気管支拡張症 / 肺非結核性抗酸菌(NTM)症 / IL-10 / 制御性自然リンパ球 / ILCreg / 1細胞分泌時間イメージング法（LCI-S) / リンパ球 / 2型自然リンパ球 / 1細胞分泌時間イメージング法(LCI-S) / 免疫フェノタイプ / 抗TSLP抗体 / 抗IL-5受容体抗体 / フェノタイプ / LCI-S / リンパ球解析 / 個別化医療 / バイオマーカー / 好酸球 / Th2細胞 / ILC2 / 難治性喘息 / オミクス / マルチオミクス / ゲノム / ドラッグスクリーニング / トランスクリプトーム / 薬剤スクリーニング / 高異型度漿液性癌 / 明細胞癌 / オルガノイド / 卵巣癌 Less

呼吸器疾患における制御性自然リンパ球（ILCreg）の解析と新規治療戦略の確立
- Principal Investigator
  
  加畑宏樹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Keio University
Elucidation of mucus abnormalities in the bronchiole of pulmonary nontuberculous mycobacterial disease and development of therapeutic strategies
- Principal Investigator
  
  朝倉崇徳
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Keio University
Optimizing personalized disease management by investigating the link between bronchial asthma, meteorological factors, and air pollution
- Principal Investigator
  
  正木克宜
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Keio University
Multi-omics of ovarian cancer organoids for development of novel therapeutics against drug-resistant ovarian cancers
- Principal Investigator
  
  CHIYODA Tatsuyuki
- Project Period (FY)
  2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Keio University
Development of a Novel Therapeutic Strategy for Refractory Asthma Based on Immune Phenotyping
- Principal Investigator
  
  Fukunaga Koichi
- Project Period (FY)
  2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Keio University
がん免疫治療下における間質軌跡地図の空間解析と新しい間質リプログラミング法の確立
- Principal Investigator
  
  田中伸之
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Keio University
未来表現型予測AIによる新たな研究体系の確立Principal Investigator
- Principal Investigator
  
  鎌谷高志
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 62:Applied informatics and related fields
- Research Institution
  Institute of Science Tokyo
  Tokyo Medical and Dental University
Identification of Treatment-Related Factors Using Multi-Region Analysis Before and After Cancer ImmunotherapyPrincipal Investigator
- Principal Investigator
  
  Kamatani Takashi
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Tokyo Medical and Dental University
Prognostic modeling of myxoid liposarcoma by gene expression and histopathology with focus on tumor immunity.Principal Investigator
- Principal Investigator
  
  Takashi Kamatani
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  The University of Tokyo

All 2025 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] High-throughput drug screening of clear cell ovarian cancer organoids reveal vulnerability to proteasome inhibitors and dinaciclib and identify AGR2 as a therapeutic target2025
- Author(s)
  Yoshimura T, Kamatani T, Ookubo A, Takahashi M, Itoh M, Ebisudani T, Masugi Y, Toyonaga T, Hamamoto J, Saotome K, Sakai K, Yoshihama T, Moritoki N, Shibata S, Yasuda H, Sato T, Sato TA, Aoki D, Yamagami W, Tsunoda T, Chiyoda T
- Journal Title
  
  Cancer Research Communications
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K21475
[Journal Article] Annexin A1 is a cell-intrinsic metalloregulator of zinc in human ILC2s2023
- Author(s)
  Irie Misato、Kabata Hiroki、Sasahara Kotaro、Kurihara Momoko、Shirasaki Yoshitaka、Kamatani Takashi、Baba Rie、Matsusaka Masako、Koga Satoshi、Masaki Katsunori、Miyata Jun、Araki Yasutomo、Kikawada Toru、Kabe Yasuaki、Suematsu Makoto、Yamagishi Mai、Uemura Sotaro、Moro Kazuyo、Fukunaga Koichi
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 6 Pages: 112610-112610
- DOI
  10.1016/j.celrep.2023.112610
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08240, KAKENHI-PROJECT-21K06845, KAKENHI-PROJECT-23K24342
[Journal Article] Time-dependent cell-state selection identifies transiently expressed genes regulating ILC2 activation2023
- Author(s)
  Tanaka Yumiko、Yamagishi Mai、Motomura Yasutaka、Kamatani Takashi、Oguchi Yusuke、Suzuki Nobutake、Kiniwa Tsuyoshi、Kabata Hiroki、Irie Misato、Tsunoda Tatsuhiko、Miya Fuyuki、Goda Keisuke、Ohara Osamu、Funatsu Takashi、Fukunaga Koichi、Moro Kazuyo、Uemura Sotaro、Shirasaki Yoshitaka
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 915-915
- DOI
  10.1038/s42003-023-05297-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18232, KAKENHI-PROJECT-21H02750, KAKENHI-PROJECT-23K24342
[Journal Article] Upregulation of IL-4 receptor signaling pathway in circulating ILC2s from asthma patients2022
- Author(s)
  Baba Rie、Kabata Hiroki、Shirasaki Yoshitaka、Kamatani Takashi、Yamagishi Mai、Irie Misato、Watanabe Risa、Matsusaka Masako、Masaki Katsunori、Miyata Jun、Moro Kazuyo、Uemura Sotaro、Fukunaga Koichi
- Journal Title
  
  Journal of Allergy and Clinical Immunology: Global
  
  Volume: 1 Issue: 4 Pages: 299-304
- DOI
  10.1016/j.jacig.2022.07.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08240, KAKENHI-PROJECT-21K18232, KAKENHI-PROJECT-23K24342, KAKENHI-PROJECT-20H04512
[Presentation] 重症喘息患者に対するベンラリズマブ投与前後のリンパ球解析2024
- Author(s)
  入江美聡、加畑宏樹、正木克宜、山岸舞、鎌谷高志、鈴川真穂、原田紀宏、宮崎泰成、桂秀樹、放生雅章、杉本直也、河野雄太、權寧博、宮田純、上村想太郎、白崎善隆、福永興壱
- Organizer
  第64回日本呼吸器学会学術大会
- Data Source
  KAKENHI-PROJECT-23K24342
[Presentation] AIとライブセルイメージングで解き明かすがん細胞と細胞障害性T細胞の相互作用ダイナミクス2024
- Author(s)
  鎌谷高志
- Organizer
  第32回Cell Death学会学術集会
- Data Source
  KAKENHI-PROJECT-23K17463
[Presentation] 重症喘息におけるベンラリズマブ投与前後のリンパ球解析　多施設共同特定臨床研究　Tokyo Asthma Study(TOAST)2024
- Author(s)
  入江美聡, 加畑宏樹, 正木克宜, 山岸舞, 鎌谷高志, 鈴川真穂, 原田紀宏, 宮崎泰成, 桂秀樹, 放生雅章, 杉本直也, 河野雄太, 權寧博, 宮田純, 上村想太郎, 白崎善隆, 福永興壱
- Organizer
  第64回日本呼吸器学会学術大会
- Data Source
  KAKENHI-PROJECT-23K24342
[Presentation] ベンチワークから臨床へ繋げる婦人科がん治療に対する新たな展望　Development of novel treatment for ovarian cancer by omics analysis using organoids2023
- Author(s)
  千代田達幸, 吉村拓馬, 高橋美央, 鎌谷高志, 平田桃, 地阪光代, 坂巻智美, 和田美智子, 坂井健良, 角田達彦, 山上亘
- Organizer
  61回　癌治療学会　ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-23K21475
[Presentation] Zinc plays an essential role in type 2 cytokine production from ILC2s in asthma2023
- Author(s)
  Hiroki Kabata, Misato Irie, Rie Baba, Yoshitaka Shirasaki, Takashi Kamatani, Mai Yamagishi, Koichi Fukunaga
- Organizer
  European Respiratory Society International Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24342
[Presentation] High-throughput drug screening using an organoid library revealed novel therapeutics and a drug target for ovarian clear cell carcinoma2023
- Author(s)
  Takuma Yoshimura, Tatsuyuki Chiyoda, Takashi Kamatani, Mio Takahashi, Kensuke Sakai, Tomoko Yoshihama, Wataru Yamagami, Tatsuhiko Tsunoda, Mamoru Tanaka, Daisuke Aoki
- Organizer
  日本産科婦人科学会　学術講演会
- Data Source
  KAKENHI-PROJECT-23K21475
[Presentation] 【若手産婦人科医がつなぐTR,基礎研究が面白い!】難治性卵巣癌の新規治療開発を目標とした,オルガノイドライブラリを用いたTR2023
- Author(s)
  吉村拓馬, 千代田達幸, 鎌谷高志, 高橋美央, 坂井健良, 山上亘, 角田達彦, 青木大輔
- Organizer
  65回　婦人科腫瘍学会
- Data Source
  KAKENHI-PROJECT-23K21475
[Presentation] Prevalence of KRAS variants in endometrial, ovarian, and cervical tumors2023
- Author(s)
  Momo Hirata, Tatsuyuki Chiyoda, Kohei Nakamura, Takuma Yoshimura, Kensuke Sakai, Tomoko Yoshihama, Kouji Banno, Takashi Iwata, Wataru Yamagami, Hiroshi Nishihara, Mamoru Tanaka, Daisuke Aoki
- Organizer
  日本産科婦人科学会　学術講演会
- Data Source
  KAKENHI-PROJECT-23K21475
[Presentation] 喘息患者の末梢血由来2型自然リンパ球のシングルセル解析2022
- Author(s)
  馬塲里英, 加畑宏樹, 桑江美聡, 渡辺理沙, 松坂雅子, 鎌谷高志, 白崎善隆, 山岸舞, 福永興壱
- Organizer
  第71回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-23K24342
[Presentation] LCI-Sを用いた2型自然リンパ球の新規制御機構の解明2022
- Author(s)
  入江美聡, 加畑宏樹, 松坂雅子, 馬塲里英, 鎌谷高志, 正木克宜, 白崎善隆, 福永興壱
- Organizer
  第62回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-23K24342
[Presentation] ヒト2型自然リンパ球における内因性活性化制御機構の解明2022
- Author(s)
  入江美聡, 加畑宏樹, 松坂雅子, 馬塲里英, 鎌谷高志, 正木克宜, 白崎善隆, 福永興壱
- Organizer
  第71回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-23K24342
[Presentation] LCI-Sを用いた喘息患者における末梢血由来2型自然リンパ球の解析2022
- Author(s)
  馬塲里英, 加畑宏樹, 桑江美聡, 渡辺理沙, 松坂雅子, 鎌谷高志, 白崎善隆, 山岸舞, 福永興壱
- Organizer
  第62回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-23K24342
[Presentation] 生物情報科学の視点から行うがん研究 ~DNA, RNA, 病理画像を用いた免疫環境解析や多領域解析を中心に~2021
- Author(s)
  鎌谷高志
- Organizer
  第19回関東骨軟部腫瘍の基礎を語る会
- Invited
- Data Source
  KAKENHI-PROJECT-20K16408
[Presentation] Immunological analysis of the tumor microenvironment for myxoid liposarcoma2020
- Author(s)
  鎌谷高志
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K16408

1. 加畑宏樹 (60528537)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
2. Fukunaga Koichi (60327517)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. 白崎善隆 (70469948)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. 垣見和宏 (80273358)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. CHIYODA Tatsuyuki (40445367)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. 角田達彦 (10273468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 茂呂和世 (90468489)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 朝倉崇徳 (10645609)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 南宮湖 (50594644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 上蓑義典 (60748789)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 正木克宜 (70570935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 宮田純 (80464866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 田中伸之 (60445244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 橋本真一 (00313099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 上村想太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kamatani Takashi 鎌谷 高志

Takashi Kamatani 鎌谷 高志

Research Projects

Research Products

Co-Researchers

呼吸器疾患における制御性自然リンパ球（ILCreg）の解析と新規治療戦略の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of mucus abnormalities in the bronchiole of pulmonary nontuberculous mycobacterial disease and development of therapeutic strategies

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Optimizing personalized disease management by investigating the link between bronchial asthma, meteorological factors, and air pollution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Multi-omics of ovarian cancer organoids for development of novel therapeutics against drug-resistant ovarian cancers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a Novel Therapeutic Strategy for Refractory Asthma Based on Immune Phenotyping

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

がん免疫治療下における間質軌跡地図の空間解析と新しい間質リプログラミング法の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

未来表現型予測AIによる新たな研究体系の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of Treatment-Related Factors Using Multi-Region Analysis Before and After Cancer ImmunotherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Prognostic modeling of myxoid liposarcoma by gene expression and histopathology with focus on tumor immunity.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] High-throughput drug screening of clear cell ovarian cancer organoids reveal vulnerability to proteasome inhibitors and dinaciclib and identify AGR2 as a therapeutic target2025

Author(s)

Journal Title

Data Source

[Journal Article] Annexin A1 is a cell-intrinsic metalloregulator of zinc in human ILC2s2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Time-dependent cell-state selection identifies transiently expressed genes regulating ILC2 activation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Upregulation of IL-4 receptor signaling pathway in circulating ILC2s from asthma patients2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] 重症喘息患者に対するベンラリズマブ投与前後のリンパ球解析2024

Author(s)

Kamatani Takashi 鎌谷高志

Takashi Kamatani 鎌谷高志

[Presentation] AIとライブセルイメージングで解き明かすがん細胞と細胞障害性T細胞の相互作用ダイナミクス2024

[Presentation] 重症喘息におけるベンラリズマブ投与前後のリンパ球解析　多施設共同特定臨床研究　Tokyo Asthma Study(TOAST)2024

[Presentation] ベンチワークから臨床へ繋げる婦人科がん治療に対する新たな展望　Development of novel treatment for ovarian cancer by omics analysis using organoids2023