Hirotsu Chieko 廣津千恵子

… Alternative Names

廣津千恵子ヒロツチエコ

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Researcher Number	90647174
Affiliation (Current)	2025: 聖マリアンナ医科大学, 医学部, 研究技術員
Affiliation (based on the past Project Information) *help	2023 – 2024: 聖マリアンナ医科大学, 医学部, 研究技術員 2021: 聖マリアンナ医科大学, 医学部, 研究技術員 2013 – 2018: 聖マリアンナ医科大学, 医学部, 研究技術員
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery / Ophthalmology Except Principal Investigator Basic Section 52010:General internal medicine-related / Collagenous pathology/Allergology
Keywords	Principal Investigator 再生 / イメージング / 細胞・組織 / 脳・神経 / 移植・再生医療 / 神経再生 / 細胞移植 / 再生医療 / シグナル伝達 / 移植 … More / 神経細胞 / iPS / 移動 / 神経 / 全トランスクリプトーム解析 / ES細胞 / 次世代シークエンサー / CRX1 / SDF1 / 視細胞前駆細胞 / CRX / 網膜前駆細胞 / ロドプシン / 視細胞 / 網膜 / iPS細胞 … More Except Principal Investigator 中枢神経損傷モデル / 硬化症 / 細胞移植 / 炎症 / 再生 / 中枢神経疾患 / 全身性エリテマトーデス / 再発性多発軟骨炎 / 炎症性腸疾患 / Th17細胞 / 腸内細菌メタゲノミクス / Tリンパ球 / ベーチェット病 / T細胞 / 腸内細菌叢メタゲノミクス Less

中枢神経障害下における移植細胞の挙動と再生機序の解明Principal Investigator
- Principal Investigator
  
  廣津千恵子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  St. Marianna University School of Medicine
Mechanism of nerve regeneration by Reelin in inflammatory demyelinating disease of the central nervous system
- Principal Investigator
  
  Arimitsu Nagisa
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  St. Marianna University School of Medicine
Neural regeneration and signal pathway after neural stem / progenitor cells transplantation in hemiplegic mice micePrincipal Investigator
- Principal Investigator
  
  Chieko Hirotsu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  St. Marianna University School of Medicine
Differentiation of retinal progenitors by chemokinePrincipal Investigator
- Principal Investigator
  
  Hirotsu Chieko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  St. Marianna University School of Medicine
Establishment of an immune regulation of T cell function through gut microbiota modulation
- Principal Investigator
  
  Shimizu Jun
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  St. Marianna University School of Medicine

All 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Neuronal cell sheets of cortical motor neuron phenotype derived from human iPS cells.2017
- Author(s)
  Suzuki N, Arimitsu N, Shimizu J, Takai K, Hirotsu C, Ueda Y, Wakisaka S, Fujiwara N, Suzuki T.
- Journal Title
  
  Cell Transplant.
  
  Volume: 26 Issue: 8 Pages: 1355-1364
- DOI
  10.1177/0963689717720280
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10743, KAKENHI-PROJECT-16K10744, KAKENHI-PROJECT-16K11334, KAKENHI-PROJECT-17K01378, KAKENHI-PROJECT-17K10009, KAKENHI-PROJECT-17K10852, KAKENHI-PROJECT-17K11494, KAKENHI-PROJECT-26462172
[Journal Article] Human iPS cell derived neural cell sheets exhibit mature neural and extendable scaffold functions and promote recovery in injured mouse spinal cords.2016
- Author(s)
  Arimitsu N, Shimizu J, Iinuma M, Umehara T, Fujiwara N, Takai K, Wakisaka S, Hirotsu C, Suzuki T, Beppu M, Niki H, Suzuki N.
- Journal Title
  
  J Stem Cell Res Med.
  
  Volume: 1 Issue: 2 Pages: 41-47
- DOI
  10.15761/jscrm.1000106
- Open Access
- Data Source
  KAKENHI-PROJECT-26501005, KAKENHI-PROJECT-16K10743
[Journal Article] Generation of Retinal Progenitor Cell Sheets which Differentiate into　Rhodopsin Positive Photoreceptors from Mouse iPS Cell Derived Retinal Progenitor Cell Clones.2015
- Author(s)
  Noboru Suzuki, Jun Shimizu, Chieko Hirotsu, Erika Takada, Nagisa Arimitsu, Yuji Ueda, Naruyoshi Fujiwara, Tomoko Suzuki, Kenji Takai.
- Journal Title
  
  ・International Journal of Ophthlmology and Clinical Research
  
  Volume: 2 Pages: 1-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670740
[Journal Article] Induction of neural cells with spinal motoneuron phenotype from human iPS cells and the transplantation to totally transected spinal cords in mice.2015
- Author(s)
  Iinuma M, Umehara T, Arimitsu N, Shimizu J, Misawa H, Takai K, Fujiwara N, Fujii A, UedaY, Wakisaka S, Suzuki T, Hirotsu C, Beppu M, Suzuki N.
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 35 Pages: 154-163
- NAID
  130005078573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670740
[Journal Article] Generation of Retinal Progenitor Cell Sheets which Differentiate into Rhodopsin Positive Photoreceptors from Mouse iPS Cell Derived Retinal Progenitor Cell Clones.2015
- Author(s)
  Suzuki N, Shimizu J, Hirotsu C, Takada E, Arimitsu N, Ueda Y, Fujiwara N, SuzukiT, Takai K.
- Journal Title
  
  International Journal of Ophthalmology and Clinical Research
  
  Volume: 2 Pages: 1-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670740
[Presentation] Reelin Signal Activation is Associated With Motor Function Recovery in the Neuron Transplantation of Hemiplegic Mice.2018
- Author(s)
  Nagisa Arimitsu, Jun Shimizu, Kenji Takai, Naruyoshi Fujiwara , Chieko Hirotsu, Yoko Okada , and Noboru Suzuki.
- Organizer
  the 51st Winter Conference on Brain Research (WCBR) .
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10743
[Presentation] Neural regeneration after transplantation of Neuronal cell sheet of cortical motor neuron phenotype.2018
- Author(s)
  Nagisa Arimitsu-Nakata, Chieko Hirotsu,Kenji Takai, Jun Shimizu,Naruyoshi Fujiwara, Yoko Okada,Noboru Suzuki
- Organizer
  the 5th TERMIS-WC 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10743
[Presentation] NEURAL REGENERATION MECHANISMS IN TRANSPLANTATION OF NEURONAL CELLS DERIVED FROM HUMAN INDUCED PLURIPOTENT STEM CELLS WITH THE EFFECT OF THEIR PARACRINE SECRETION.2018
- Author(s)
  Nagisa Arimitsu, Jun Shimizu, Kenji Takai, Naruyoshi Fujiwara, Chieko Hirotsu, Yoko Okada and Noboru Suzuki
- Organizer
  International society for stem cell research 14th annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10743
[Presentation] 幹細胞由来神経細胞移植による脳損傷マウスにおける神経再生.2017
- Author(s)
  有光なぎさ, 廣津千恵子, 高井憲治, 藤原成芳, 岡田容子, 清水潤, 鈴木登.
- Organizer
  第１６回日本再生医療学会総会
- Place of Presentation
  宮城県仙台市(仙台国際センター)
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-16K10743
[Presentation] ヒトiPS由来神経細胞移植による認知機能改善と改善メカニズムについての検討2017
- Author(s)
  藤原成芳、岡田容子、高井憲治、廣津千恵子、有光なぎさ、高田えりか、清水潤、鈴木登.
- Organizer
  第１６回日本再生医療学会総会
- Place of Presentation
  宮城県仙台市(仙台国際センター)
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-16K10743
[Presentation] 脳損傷マウスに対する幹細胞由来神経細胞移植による神経再生.2016
- Author(s)
  有光なぎさ, 廣津千恵子, 高井憲治, 藤原成芳, 清水潤, 鈴木登.
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  神奈川県横浜市(パシフィコ横浜)
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-16K10743
[Presentation] ヒトiPS細胞から誘導した神経細胞移植による空間機能の改善と改善メカニズムの検討.2014
- Author(s)
  藤原成芳, 高井憲治, 高田えりか, 廣津千恵子, 飯沼雅央, 三澤寛子, 有光なぎさ, 清水潤，鈴木登.
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-25670740
[Presentation] Differentiation of cholinergic neurons from hiPS cells and restration of cognitive function by their transplantation in mice with dementia.2013
- Author(s)
  Naruyoshi Fujiwara, Kenji Takai, Erika Takada, Chieko Hirotsu, Nagisa Arimitsu, Asako Saito, Jun Shimizu, Noboru Suzuki.
- Organizer
  International Society for Stem Cell Research 11th Annual Meeting
- Place of Presentation
  BOSTON (USA)
- Data Source
  KAKENHI-PROJECT-25670740
[Presentation] ヒトiPS由来神経細胞移植による空間記憶能の改善と改善メカニズムについての検討.
- Author(s)
  藤原成芳, 高井憲治, 鈴木千佳, 廣津千恵子, 高田えりか, 有光なぎさ, 白土崇輝, 清水潤，鈴木登.
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  横浜市(パシフィコ横浜)
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-25670740
[Presentation] Restoration of spatial memory dysfunction of human APP transgenic mice by transplantation of neuronal precursors derived from hIPS cells.
- Author(s)
  Naruyoshi Fujiwara, Kenji Takai, Erika Takada, Chieko Hirotsu, Nagisa Arimitsu, Jun Shimizu and Noboru Suzuki.
- Organizer
  International Society for Stem Cell Research 12th Annual Meeting
- Place of Presentation
  Vancouver,Canada
- Year and Date
  2014-06-18 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-25670740

1. Arimitsu Nagisa (40408688)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
2. Suzuki Noboru (40235982)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. Shimizu Jun (30509964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Takai Kenji (60121167)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Fujiwara Naruyoshi (50365425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. Takada Erika (90398959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 村山正承 (60737675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hirotsu Chieko 廣津 千恵子

廣津 千恵子 ヒロツ チエコ

Research Projects

Research Products

Co-Researchers

中枢神経障害下における移植細胞の挙動と再生機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of nerve regeneration by Reelin in inflammatory demyelinating disease of the central nervous system

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Neural regeneration and signal pathway after neural stem / progenitor cells transplantation in hemiplegic mice micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Differentiation of retinal progenitors by chemokinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of an immune regulation of T cell function through gut microbiota modulation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Neuronal cell sheets of cortical motor neuron phenotype derived from human iPS cells.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human iPS cell derived neural cell sheets exhibit mature neural and extendable scaffold functions and promote recovery in injured mouse spinal cords.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation of Retinal Progenitor Cell Sheets which Differentiate into Rhodopsin Positive Photoreceptors from Mouse iPS Cell Derived Retinal Progenitor Cell Clones.2015

Author(s)

Journal Title

Data Source

[Journal Article] Induction of neural cells with spinal motoneuron phenotype from human iPS cells and the transplantation to totally transected spinal cords in mice.2015

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Generation of Retinal Progenitor Cell Sheets which Differentiate into Rhodopsin Positive Photoreceptors from Mouse iPS Cell Derived Retinal Progenitor Cell Clones.2015

Author(s)

Journal Title

Data Source

[Presentation] Reelin Signal Activation is Associated With Motor Function Recovery in the Neuron Transplantation of Hemiplegic Mice.2018

Author(s)

Organizer

Data Source

[Presentation] Neural regeneration after transplantation of Neuronal cell sheet of cortical motor neuron phenotype.2018

Author(s)

Organizer

Data Source

[Presentation] NEURAL REGENERATION MECHANISMS IN TRANSPLANTATION OF NEURONAL CELLS DERIVED FROM HUMAN INDUCED PLURIPOTENT STEM CELLS WITH THE EFFECT OF THEIR PARACRINE SECRETION.2018

Author(s)

Organizer

Data Source

[Presentation] 幹細胞由来神経細胞移植による脳損傷マウスにおける神経再生.2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ヒトiPS由来神経細胞移植による認知機能改善と改善メカニズムについての検討2017

Author(s)

Organizer

Place of Presentation

Hirotsu Chieko 廣津千恵子

廣津千恵子ヒロツチエコ

[Journal Article] Generation of Retinal Progenitor Cell Sheets which Differentiate into　Rhodopsin Positive Photoreceptors from Mouse iPS Cell Derived Retinal Progenitor Cell Clones.2015