Yamamoto Akihisa 山本暁久

Researcher Number	90706805
Other IDs
Affiliation (Current)	2025: 東京都立大学, システムデザイン研究科, 准教授 2025: 国立研究開発法人理化学研究所, 数理創造プログラム, 研究員
Affiliation (based on the past Project Information) *help	2024: 国立研究開発法人理化学研究所, 数理創造プログラム, 研究員 2018 – 2023: 京都大学, 高等研究院, 特定助教 2017: 京都大学, 医学研究科, 特定研究員 2016: 京都大学, 物質－細胞統合システム拠点, 特定研究員 2015: 京都大学, 物質-細胞統合システム拠点, 研究員 2015: 京都大学, 物質－細胞統合システム拠点, 研究員 2014: 京都大学, 物質‐細胞統合システム拠点, 研究員
Review Section/Research Field	Principal Investigator Biological physics/Chemical physics/Soft matter physics / Basic Section 90110:Biomedical engineering-related / Basic Section 13040:Biophysics, chemical physics and soft matter physics-related Except Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields
Keywords	Principal Investigator ソフトマター物理 / 生体膜 / メカノバイオロジー / 組織恒常性 / ヒト角膜内皮 / 細胞微小環境 / 秩序構造 / 上皮組織 / 医学物理 / 位相的データ解析 … More / 自発構造秩序 / 細胞集団 / 中性子散乱 / 幹細胞 / 界面相互作用 / 細胞接着 / 力学特性 / 脂質膜 / 糖鎖 / 糖脂質 / 酸化脂質 / リポポリマー / モデル生体膜 / ラングミュア膜 / 微小角X線蛍光散乱 / 静電相互作用 / X線反射率 / X線蛍光散乱 / 生物物理 … More Except Principal Investigator 磁気共鳴イメージング / リアルタイム計測 / Analytic BoC / メタボリックシンドローム / 生体外モデル / 生体外モデルデバイス / 細胞微小環境モデル / 細胞 / オルガノイド / リアルタイムモニタリング / 量子センシング / マイクロシステム / 細胞代謝 / 生体模倣システム Less

ヒト角膜内皮疾患における細胞外基質の非一様化に対する内皮細胞の応答機構の解明Principal Investigator
- Principal Investigator
  
  山本暁久
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Institute of Physical and Chemical Research
  Kyoto University
Phase states and dynamics of two dimensional cell ensembles: Exploration of methodology to quantify local order structuresPrincipal Investigator
- Principal Investigator
  
  Yamamoto Akihisa
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 13040:Biophysics, chemical physics and soft matter physics-related
- Research Institution
  Kyoto University
Japanese-German Joint Research on Real Time Monitoring Technology of Cellular Metabolism in Vitro Model Device
- Principal Investigator
  
  TABATA OSAMU
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kyoto University of Advanced Science
  Kyoto University
Quantification of mechanical interactions between glycolipid membrane and stem cells towards physical understanding of cell adhesionPrincipal Investigator
- Principal Investigator
  
  Yamamoto Akihisa
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological physics/Chemical physics/Soft matter physics
- Research Institution
  Kyoto University
Exploitation of technique for precise measurement of hierarchical structure and ion-specific density distribution of biomembrane interfacesPrincipal Investigator
- Principal Investigator
  
  Yamamoto Akihisa
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological physics/Chemical physics/Soft matter physics
- Research Institution
  Kyoto University

All 2022 2020 2019 2018 2017 2015

All Journal Article Presentation Patent

[Journal Article] Superiority of Mature Differentiated Cultured Human Corneal Endothelial Cell Injection Therapy for Corneal Endothelial Failure2022
- Author(s)
  UENO MORIO、TODA MUNETOYO、NUMA KOHSAKU、TANAKA HIROSHI、IMAI KOJIRO、BUSH JOHN、TERAMUKAI SATOSHI、OKUMURA NAOKI、KOIZUMI NORIKO、YAMAMOTO AKIHISA、TANAKA MOTOMU、SOTOZONO CHIE、HAMURO JUNJI、KINOSHITA SHIGERU
- Journal Title
  
  American Journal of Ophthalmology
  
  Volume: 237 Pages: 267-277
- DOI
  10.1016/j.ajo.2021.11.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00661, KAKENHI-PROJECT-20H01870, KAKENHI-PROJECT-21K09725, KAKENHI-PLANNED-19H05719
[Journal Article] Glycogen accumulation, central carbon metabolism, and aging of hematopoietic stem and progenitor cells2020
- Author(s)
  Poisa-Beiro Laura、Thoma Judith、Landry Jonathan、Sauer Sven、Yamamoto Akihisa、Eckstein Volker、Romanov Natalie、Raffel Simon、Hoffmann Georg F.、Bork Peer、Benes Vladimir、Gavin Anne-Claude、Tanaka Motomu、Ho Anthony D.
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1-11
- DOI
  10.1038/s41598-020-68396-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0306, KAKENHI-PROJECT-20H00661
[Journal Article] A Non-Invasive Physical Biomarker for Predictive Diagnosis of In Vitro Cell Sources and Restoring Human Corneal Endothelium2019
- Author(s)
  Akihisa Yamamoto, Hiroshi Tanaka, Munetoyo Toda, Chie Sotozono, Junji Hamuro, Shigeru Kinoshita, Morio Ueno, and Motomu Tanaka
- Journal Title
  
  Nature Biomedical Engineering
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K05515
[Journal Article] Long-Range Lateral Correlation between Self-Assembled Domains of Fluorocarbon-Hydrocarbon Tetrablocks by Quantitative GISAXS2019
- Author(s)
  Wasim Abuillan, Mariam Veschgini, Salome Mielke, Akihisa Yamamoto, Xianhe Liu, Oleg Konovalov, Marie Pierre Krafft, and Motomu Tanaka
- Journal Title
  
  ChemPhysChem
  
  Volume: 20 Issue: 6 Pages: 898-904
- DOI
  10.1002/cphc.201800967
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K05515
[Journal Article] Lensless Tomographic Imaging of Near Surface Structures of Frozen Hydrated Malaria-Infected Human Erythrocytes by Coherent X-Ray Diffraction Microscopy2017
- Author(s)
  Frank, Viktoria; Chushkin, Yuriy; Froehlich, Benjamin; Abuillan, Wasim; Rieger, Harden; Becker, Alexandra S.; Yamamoto, Akihisa; Rossetti, Fernanda F.; Kaufmann, Stefan、Lanzer, Michael; Zontone, Federico; Tanaka, Motomu
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 1-9
- DOI
  10.1038/s41598-017-14586-4
- NAID
  120006540180
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K05515, KAKENHI-PROJECT-17H00855
[Journal Article] Size, Shape, and Lateral Correlation of Highly Uniform, Mesoscopic, Self-Assembled Domains of Fluorocarbon-Hydrocarbon Diblocks at the Air/Water Interface: A GISAXS Study2017
- Author(s)
  Veschgini, Mariam; Abuillan, Wasim; Inoue, Shigeto; Yamamoto, Akihisa; Mielke, Salome; Liu, Xianhe; Konovalov, Oleg; Krafft, Marie Pierre; Tanaka, Motomu
- Journal Title
  
  ChemPhysChem
  
  Volume: 18 Issue: 19 Pages: 2791-2798
- DOI
  10.1002/cphc.201700325
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K05515
[Journal Article] Ion-Specific Modulation of Interfacial Interaction Potentials between Solid Substrates and Cell-Sized Particles Mediated via Zwitterionic, Super-Hydrophilic Poly(sulfobetaine) Brushes2017
- Author(s)
  Higaki, Y.; Froehlich, B.; Yamamoto, A.; Murakami, R.; Kaneko, M.; Takahara, A.; Tanaka, M.
- Journal Title
  
  The Journal of Physical Chemistry B
  
  Volume: 121 Issue: 6 Pages: 1396-1404
- DOI
  10.1021/acs.jpcb.6b11540
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H00802, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-26247070, KAKENHI-PROJECT-16KT0070, KAKENHI-PROJECT-16K05515
[Journal Article] Dynamic Mechano-Regulation of Myoblast Cells on Supramolecular Hydrogels Cross-Linked by Reversible Host-Guest Interactions2017
- Author(s)
  Hoerning, Marcel; Nakahata, Masaki; Linke, Philipp; Yamamoto, Akihisa; Veschgini, Mariam; Kaufmann, Stefan; Takashima, Yoshinori; Harada, Akira; Tanaka, Motomu
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 7757-7757
- DOI
  10.1038/s41598-017-07934-x
- NAID
  120006366779
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K05515, KAKENHI-PROJECT-16K18525, KAKENHI-PUBLICLY-16H00802, KAKENHI-PROJECT-16K14065
[Journal Article] Influence of length and conformation of saccharide head groups on the mechanics of glycolipid membranes: Unraveled by off-specular neutron scattering2015
- Author(s)
  Akihisa Yamamoto, Wasim Abuillan, Alexandra S. Burk, Alexander Koerner, Annika Ries, Daniel B. Werz, Bruno Deme, and Motomu Tanaka
- Journal Title
  
  The Journal of Chemical Physics
  
  Volume: 142 Issue: 15 Pages: 154907-154907
- DOI
  10.1063/1.4918585
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26800223, KAKENHI-PUBLICLY-26103521, KAKENHI-PROJECT-26247070
[Patent] 細胞評価方法、細胞評価装置、及び細胞評価プログラム2018
- Inventor(s)
  田中（求）、山本、上野、羽室、木下、田中（寛）、戸田、外園
- Industrial Property Rights Holder
  田中（求）、山本、上野、羽室、木下、田中（寛）、戸田、外園
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-16K05515
[Presentation] 細胞集団秩序に基づくヒト角膜内皮組織再生の長期予後評価2022
- Author(s)
  山本暁久
- Organizer
  第3回医学と数理
- Invited
- Data Source
  KAKENHI-PROJECT-20H01870
[Presentation] Vertical Fine Structures and Electrostatics of Superhydrophilic Polymer Brushes2015
- Author(s)
  Akihisa Yamamoto, Shigeto Inoue, Taichi Habe, Yuji Higaki, Motoyasu Kobayashi, Wasim Abuillan, Oleg Konovalov, Atsushi Takahara, and Motomu Tanaka
- Organizer
  iCeMS international symposium "Hierarchical Dynamics in Soft Materials and Biological Matter"
- Place of Presentation
  京都大学
- Year and Date
  2015-09-23
- Data Source
  KAKENHI-PROJECT-26800223

1. 上野盛夫 (40426531)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. TABATA OSAMU (20288624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 亀井謙一郎 (00588262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 平井義和 (40452271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 四竈泰一 (80456152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 巽和也 (90372854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 田中求

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Yamamoto Akihisa 山本 暁久

Research Projects

Research Products

Co-Researchers

ヒト角膜内皮疾患における細胞外基質の非一様化に対する内皮細胞の応答機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Phase states and dynamics of two dimensional cell ensembles: Exploration of methodology to quantify local order structuresPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Japanese-German Joint Research on Real Time Monitoring Technology of Cellular Metabolism in Vitro Model Device

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Quantification of mechanical interactions between glycolipid membrane and stem cells towards physical understanding of cell adhesionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exploitation of technique for precise measurement of hierarchical structure and ion-specific density distribution of biomembrane interfacesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Superiority of Mature Differentiated Cultured Human Corneal Endothelial Cell Injection Therapy for Corneal Endothelial Failure2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glycogen accumulation, central carbon metabolism, and aging of hematopoietic stem and progenitor cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Non-Invasive Physical Biomarker for Predictive Diagnosis of In Vitro Cell Sources and Restoring Human Corneal Endothelium2019

Author(s)

Journal Title

Data Source

[Journal Article] Long-Range Lateral Correlation between Self-Assembled Domains of Fluorocarbon-Hydrocarbon Tetrablocks by Quantitative GISAXS2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lensless Tomographic Imaging of Near Surface Structures of Frozen Hydrated Malaria-Infected Human Erythrocytes by Coherent X-Ray Diffraction Microscopy2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Size, Shape, and Lateral Correlation of Highly Uniform, Mesoscopic, Self-Assembled Domains of Fluorocarbon-Hydrocarbon Diblocks at the Air/Water Interface: A GISAXS Study2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ion-Specific Modulation of Interfacial Interaction Potentials between Solid Substrates and Cell-Sized Particles Mediated via Zwitterionic, Super-Hydrophilic Poly(sulfobetaine) Brushes2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dynamic Mechano-Regulation of Myoblast Cells on Supramolecular Hydrogels Cross-Linked by Reversible Host-Guest Interactions2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Influence of length and conformation of saccharide head groups on the mechanics of glycolipid membranes: Unraveled by off-specular neutron scattering2015

Author(s)

Journal Title

DOI

Data Source

Yamamoto Akihisa 山本暁久