Hirai Yuya 平井悠哉

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HIRAI Yuya 平井悠哉

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Researcher Number	90710369
Other IDs
Affiliation (Current)	2025: 大阪歯科大学, 歯学部, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 大阪歯科大学, 歯学部, 講師 2019 – 2020: 大阪歯科大学, 歯学部, 助教 2014 – 2016: 大阪歯科大学, 歯学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 49060:Virology-related / Basic Section 44010:Cell biology-related / Molecular biology Except Principal Investigator Basic Section 49060:Virology-related
Keywords	Principal Investigator RNP / 液-液相分離 / クロマチン / ホスホプロテイン / ヌクレオプロテイン / 核 / 生体分子凝縮体 / 封入体 / ニャマニニウイルス / モノネガウイルス … More / membraneless organelles / 天然変性領域 / ストレス顆粒 / 核小体 / DDX17 / RNAヘリカーゼ / 超解像顕微鏡法 / RBMX / BDV / 分裂期染色体 … More Except Principal Investigator クライオ電子顕微鏡 / ヌクレオカプシド / モノネガウイルス / RNAウイルス Less

Mechanism of mononegavirus nucleocapsid formation
- Principal Investigator
  
  杉田征彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Kyoto University
Elucidation of structure-function relationships of nuclear viral inclusion bodies formed by liquid-liquid phase separationPrincipal Investigator
- Principal Investigator
  
  平井悠哉
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Osaka Dental University
Elucidation of the mechanism by which RNA helicases regulate the functional relationship between nucleoli and stress granules.Principal Investigator
- Principal Investigator
  
  Hirai Yuya
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Osaka Dental University
The elucidation of the localization mechanism of RNP to the mitotic chromosomes by using the virusPrincipal Investigator
- Principal Investigator
  
  HIRAI Yuya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Osaka Dental University

All 2023 2020 2019 2017 2016 2015 Other

All Journal Article Presentation

[Journal Article] Boron Clusters Alter the Membrane Permeability of Dicationic Fluorescent DNA-Staining Dyes2023
- Author(s)
  Hirai Yuya、Makita Yoshimasa、Asaoka Jun、Aoyagi Yuka、Nomoto Akihiro、Okamura Hideyuki、Fujiwara Shin-ichi
- Journal Title
  
  ACS Omega
  
  Volume: 8 Issue: 38 Pages: 35321-35327
- DOI
  10.1021/acsomega.3c05156
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06574, KAKENHI-PROJECT-18K09629
[Journal Article] Differential roles of two DDX17 isoforms in the formation of membraneless organelles.2020
- Author(s)
  Hirai Y, Domae E, Yoshikawa Y, Tomonaga K.
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: - Issue: 1 Pages: 33-40
- DOI
  10.1093/jb/mvaa023
- NAID
  40022279143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16133, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429
[Journal Article] Borna Disease Virus Assembles Porous Cage-like Viral Factories in the Nucleus.2016
- Author(s)
  Hirai Y, Hirano Y, Matsuda A, Hiraoka Y, Honda T, Tomonaga K.
- Journal Title
  
  The Journal of biological chemistry.
  
  Volume: 291 Issue: 50 Pages: 25789-25798
- DOI
  10.1074/jbc.m116.746396
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01309, KAKENHI-PUBLICLY-16H01440, KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-16H06430, KAKENHI-PROJECT-26251037, KAKENHI-PROJECT-26253027, KAKENHI-PROJECT-15K14500, KAKENHI-PROJECT-26870286, KAKENHI-PROJECT-15K08496
[Journal Article] X-linked RNA-binding motif protein (RBMX) is required for the maintenance of Borna disease virus nuclear viral factories.2015
- Author(s)
  Hirai Y, Honda T, Makino A, Watanabe Y, Tomonaga K.
- Journal Title
  
  J Gen Virol.
  
  Volume: 96 Issue: 11 Pages: 3198-203
- DOI
  10.1099/jgv.0.000273
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08496, KAKENHI-PROJECT-26870286, KAKENHI-PUBLICLY-15H01259
[Presentation] ボルナ病ウイルス核タンパク質－RNA複合体形成機構の解明2023
- Author(s)
  後藤真也，平井悠哉，朝長啓造，野田岳志，堀江真行，杉田征彦
- Organizer
  第70回日本ウイルス学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06574
[Presentation] ボルナ病ウイルス1型・核タンパク質－RNA複合体の三次元構造2023
- Author(s)
  杉田征彦，平井悠哉，後藤真也，朝長啓造，野田岳志，堀江真行
- Organizer
  第70回日本ウイルス学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06574
[Presentation] ニャマニニウイルスは核内に特異な封入体を形成する2023
- Author(s)
  平井悠哉，堀江真行
- Organizer
  第70回日本ウイルス学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06574
[Presentation] RNAヘリカーゼであるDDX17の2つのアイソフォームの機能相違の解析2019
- Author(s)
  平井悠哉，牧野晶子，岡村英幸，朝長啓造
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K16133
[Presentation] 核内アクチンによるボルナ病ウイルスのRNPの機能制御機構の解明2017
- Author(s)
  平井悠哉
- Organizer
  6th Negative Strand Virus-Japan Symposium
- Place of Presentation
  ラグナガーデンホテル（宜野湾市）
- Year and Date
  2017-01-16
- Data Source
  KAKENHI-PROJECT-26870286
[Presentation] The analysis of the possible relationship between Borna disease virus and nuclear actin2016
- Author(s)
  Yuya Hirai, Akiko Makino, Tomoyuki Honda, Hideyuki Okamura, Keizo Tomonaga
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌コンベンションセンター（札幌市）
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-26870286
[Presentation] ボルナ病ウイルス特異的核内構造体の構造に影響を与える宿主因子の解明2016
- Author(s)
  平井悠哉
- Organizer
  5th Negative Strand Virus-Japan Symposium
- Place of Presentation
  ホテルモントレ沖縄
- Year and Date
  2016-01-25
- Data Source
  KAKENHI-PROJECT-26870286
[Presentation] RBMXはボルナウイルスが形成する核内構造体の構造を維持する2015
- Author(s)
  平井悠哉，本田知之，牧野晶子，岡村英幸，朝長啓造
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26870286
[Presentation] Molecular evolution of Osteoclasts2015
- Author(s)
  Hideyuki Okamura，Yuya Hirai
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26870286
[Presentation] 超解像顕微鏡法によるボルナウイルス核内封入体の構造および機能の解明
- Author(s)
  平井悠哉，平野泰弘，本田知之，牧野晶子，平岡泰，朝長啓造．
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-26870286
[Presentation] 超解像顕微鏡法によるボルナウイルス特異的核内構造体の構造および機能の解明
- Author(s)
  平井悠哉，平野泰弘，本田知之，平岡泰，朝長啓造
- Organizer
  第32回染色体ワークショップ
- Place of Presentation
  安芸グランドホテル（広島県・廿日市市）
- Year and Date
  2014-12-15 – 2014-12-17
- Data Source
  KAKENHI-PROJECT-26870286
[Presentation] 超解像顕微鏡法によるボルナウイルス特異的核内封入体の構造観察および機能の解明
- Author(s)
  平井悠哉
- Organizer
  4th Negative Strand Virus-Japan Symposium
- Place of Presentation
  沖縄ラグナガーデンホテル（沖縄県・宜野湾市）
- Year and Date
  2015-01-19 – 2015-01-21
- Data Source
  KAKENHI-PROJECT-26870286

1. 杉田征彦 (00734469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 堀江真行 (20725981)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. HIRAOKA Yasushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 本田知之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hirai Yuya 平井 悠哉

HIRAI Yuya 平井 悠哉

Research Projects

Research Products

Co-Researchers

Mechanism of mononegavirus nucleocapsid formation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of structure-function relationships of nuclear viral inclusion bodies formed by liquid-liquid phase separationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism by which RNA helicases regulate the functional relationship between nucleoli and stress granules.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The elucidation of the localization mechanism of RNP to the mitotic chromosomes by using the virusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Boron Clusters Alter the Membrane Permeability of Dicationic Fluorescent DNA-Staining Dyes2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differential roles of two DDX17 isoforms in the formation of membraneless organelles.2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Borna Disease Virus Assembles Porous Cage-like Viral Factories in the Nucleus.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] X-linked RNA-binding motif protein (RBMX) is required for the maintenance of Borna disease virus nuclear viral factories.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] ボルナ病ウイルス核タンパク質－RNA複合体形成機構の解明2023

Author(s)

Organizer

Data Source

[Presentation] ボルナ病ウイルス1型・核タンパク質－RNA複合体の三次元構造2023

Author(s)

Organizer

Data Source

[Presentation] ニャマニニウイルスは核内に特異な封入体を形成する2023

Author(s)

Organizer

Data Source

[Presentation] RNAヘリカーゼであるDDX17の2つのアイソフォームの機能相違の解析2019

Author(s)

Organizer

Data Source

[Presentation] 核内アクチンによるボルナ病ウイルスのRNPの機能制御機構の解明2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] The analysis of the possible relationship between Borna disease virus and nuclear actin2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ボルナ病ウイルス特異的核内構造体の構造に影響を与える宿主因子の解明2016

Author(s)

Hirai Yuya 平井悠哉

HIRAI Yuya 平井悠哉