Ito Hideaki 伊藤秀明

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ITO HIDEAKI 伊藤秀明

ITO Hideaki 伊藤秀明

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Researcher Number	90711276
Other IDs
Affiliation (Current)	2025: 愛知医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2019 – 2023: 愛知医科大学, 医学部, 講師 2016 – 2018: 愛知医科大学, 医学部, 助教 2014: 愛知医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 49020:Human pathology-related / Human pathology Except Principal Investigator Human pathology
Keywords	Principal Investigator 浸潤 / ソニックヘッジホッグ / STIL / 唾液腺癌 / ΔNp63 / 粘表皮癌 / 細胞極性 / タイトジャンクション / 乳癌 / 消化器・唾液腺 … More / 病理学 / 細胞骨格 / 膵臓癌 / 浸潤突起 … More Except Principal Investigator DNA複製 / クロマチン制御 / 標的遺伝子 / 転写抑制因子 / DCIS / FAM64A / TSHZ2 / Hedgehog / 遺伝子制御 / 乳癌 / 分子病理 / Pak1 / ArhGEF7 / 細胞運動 / SIL / 膵臓癌 / ヘッジホッグ Less

粘表皮癌におけるΔNp63陽性細胞先導による分子浸潤メカニズムの解明Principal Investigator
- Principal Investigator
  
  伊藤秀明
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Aichi Medical University
Mechanism of tight junction attenuation by STIL and its application to the pathological diagnosis of ductal carcinoma in situ of the breastPrincipal Investigator
- Principal Investigator
  
  Hideaki Ito
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Aichi Medical University
The role of STIL in invadopodia formation of pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  Ito Hideaki
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Aichi Medical University
Downstream of newly identified transcriptional repressor and its role in the progression of non-invasive breast cancer.
- Principal Investigator
  
  KASAI KENJI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Aichi Medical University
Hedgehog signaling molecule SIL regulates the migration and progression of pancreatic ductal adenocarcinoma.
- Principal Investigator
  
  KASAI Kenji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Aichi Medical University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation Patent

[Journal Article] Establishment of Mucoepidermoid Carcinoma Cell Lines from Surgical and Recurrence Biopsy Specimens2023
- Author(s)
  Yamanaka S, Suzuki S, Ito H, Sivasundaram K, Hanamura I, Okubo I, Yoshikawa K, Ono S, Takahara T, Satou A, Tsuzuki T, Ueda R, Ogawa T, Fujimoto Y.
- Journal Title
  
  International journal of molecular sciences
  
  Volume: 24 Issue: 2 Pages: 1722-1722
- DOI
  10.3390/ijms24021722
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07203, KAKENHI-PROJECT-21K08427, KAKENHI-PROJECT-20K16205, KAKENHI-PROJECT-17K11301, KAKENHI-PROJECT-19K09292, KAKENHI-PROJECT-22K08516, KAKENHI-PROJECT-22K08985
[Journal Article] ENTREP/FAM189A2 encodes a new ITCH ubiquitin ligase activator that is downregulated in breast cancer2022
- Author(s)
  Takumi Tsunoda, Miho Riku, Norika Yamada, Hikaru Tsuchiya, Takuya Tomita, Minako Suzuki, Mari Kizuki, Akihito Inoko, Hideaki Ito, Kenta Murotani, Hideki Murakami, Yasushi Saeki, Kenji Kasai
- Journal Title
  
  EMBO reports
  
  Volume: 23 Issue: 2
- DOI
  10.15252/embr.202051182
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07449, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-19K06671, KAKENHI-PROJECT-20K16182, KAKENHI-PROJECT-20K16205
[Journal Article] Indispensable role of STIL in the regulation of cancer cell motility through the lamellipodial accumulation of ARHGEF7-PAK1 complex2020
- Author(s)
  Hideaki Ito, Takumi Tsunoda, Miho Riku, Shingo Inaguma, Akihito Inoko, Hideki Murakami, Hiroshi Ikeda, Michiyuki Matsuda & Kenji Kasai
- Journal Title
  
  Oncogene
  
  Volume: 39 Issue: 9 Pages: 1931-1943
- DOI
  10.1038/s41388-019-1115-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06671, KAKENHI-PROJECT-19K07449, KAKENHI-PROJECT-16K19091, KAKENHI-PROJECT-16H06280, KAKENHI-PLANNED-15H05949, KAKENHI-PROJECT-19H00993
[Journal Article] Image cytometric detection and elucidation of proliferative capability of chromosome doubling cells2019
- Author(s)
  伊藤秀明, 古屋智子, 池本健三, 佐々木功典, 小賀厚徳
- Journal Title
  
  Cytometry Research
  
  Volume: 29 Issue: 2 Pages: 29-34
- DOI
  10.18947/cytometryresearch.29.2_29
- NAID
  130007751068
- ISSN
  0916-6920, 2424-0664
- Year and Date
  2019-11-25
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19091
[Journal Article] GLI1 orchestrates CXCR4/CXCR7 signaling to enhance migration and metastasis of breast cancer cells2015
- Author(s)
  Shingo Inaguma, Miho Riku, Hideaki Ito, Takumi Tsunoda, Hiroshi Ikeda, Kenji Kasai
- Journal Title
  
  Oncotarget
  
  Volume: Vol6, No32 Issue: 32 Pages: 33648-33657
- DOI
  10.18632/oncotarget.5203
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08358
[Journal Article] Down-regulation of the zinc-finger homeobox protein TSHZ2 releases GLI1 from the nuclear repressor complex to restore its transcriptional activity during mammary tumorigenesis2015
- Author(s)
  Miho Riku, Shingo Inaguma, Hideaki Ito, Takumi Tsunoda, Hiroshi Ikeda, Kenji Kasai
- Journal Title
  
  Oncotarget
  
  Volume: vol7, No5 Issue: 5 Pages: 5690-5701
- DOI
  10.18632/oncotarget.6788
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08358
[Patent] STIL-ARHGEF7シグナルの検出方法及びその使用2023
- Inventor(s)
  伊藤秀明
- Industrial Property Rights Holder
  伊藤秀明
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-122077
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-20K16205
[Presentation] 中心小体複製因子STILによる細胞周期チェックポイント抑制によるアポトーシス回避2024
- Author(s)
  鈴木佳稔、伊藤秀明、大橋明子、山田徳香、猪子誠人、中村律子、大西紘二、都築豊徳、笠井謙次
- Organizer
  第113回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-20K16205
[Presentation] STIL（SCL/TAL1 interrupting locus）の膵臓癌細胞浸潤における機能解析2023
- Author(s)
  伊藤秀明
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20K16205
[Presentation] 中心体複製関連因子STILの癌細胞遊走・浸潤における機能解析2023
- Author(s)
  伊藤秀明
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20K16205
[Presentation] 中心小体複製関連因子STILのCortactinを介した浸潤機構の解明2023
- Author(s)
  伊藤秀明、猪子誠人、陸美穂、大西紘二、笠井謙次
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-20K16205
[Presentation] 中心小体複製関連因子STILのCortactinを介した浸潤機構の解明2023
- Author(s)
  伊藤秀明, 猪子誠人, 陸美穂, 中村律子, 大西紘二, 笠井謙次
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-20K16205
[Presentation] STIL(SCL/TAL1 interrupting locus)による浸潤突起形成機構2021
- Author(s)
  伊藤秀明, 猪子誠人, 陸美穂, 村上秀樹, 笠井謙次
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-20K16205
[Presentation] STIL（SCL/TAL1 interrupting locus）の膵臓癌細胞浸潤における機能解析2021
- Author(s)
  伊藤秀明
- Organizer
  第 39 回日本ヒト細胞学会学術集会
- Data Source
  KAKENHI-PROJECT-20K16205
[Presentation] 膵臓癌における中心小体複製関連因子STIL(SCL/TAL1 interrupting locus)による細胞遊走亢進機構の解明2020
- Author(s)
  伊藤秀明, 猪子誠人, 陸美穂, 村上秀樹, 笠井謙次
- Organizer
  第30回日本サイトメトリー学会学術集会
- Data Source
  KAKENHI-PROJECT-20K16205
[Presentation] STIL（SCL/TAL1 interrupting locus）の膵臓癌細胞遊走における機能解析2019
- Author(s)
  伊藤秀明　稲熊真悟　角田拓実　陸美穂　村上秀樹　松田道行　笠井謙次
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K19091
[Presentation] STIL（SCL/TAL1 interrupting locus)の膵臓癌細胞遊走における機能解析2018
- Author(s)
  伊藤秀明, 稲熊真悟, 角田拓実, 村上秀樹, 池田洋, 笠井謙次
- Organizer
  第36回ヒト細胞学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19091
[Presentation] STIL（SCL/TAL1 interrupting locus)の膵臓癌細胞遊走時先進部における機能解析2018
- Author(s)
  伊藤秀明, 稲熊真悟, 角田拓実, 村上秀樹, 池田洋, 笠井謙次
- Organizer
  第64回日本病理学会秋期特別総会
- Data Source
  KAKENHI-PROJECT-16K19091
[Presentation] 細胞周期・DNA ploidy解析とイメージサイトメトリー2018
- Author(s)
  伊藤秀明, 古屋智子, 小賀厚徳, 笠井謙次, 佐々木功典
- Organizer
  第28回日本サイトメトリー学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K19091
[Presentation] 膵臓癌細胞遊走におけるSTIL(SCL/TAL1 interrupting locus)の細胞骨格制御機構2017
- Author(s)
  伊藤秀明、稲熊真悟、角田拓実、池田洋、笠井謙次
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-16K19091
[Presentation] 細胞運動におけるSTIL(SCL/TAL1 interrupting locus)の機能解析2017
- Author(s)
  伊藤秀明、稲熊真悟、角田拓実、池田洋、笠井謙次
- Organizer
  第27回日本サイトメトリー学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19091
[Presentation] STIL(SCL/TAL1 interrupting locus)による膵臓癌細胞運動能制御機構2016
- Author(s)
  伊藤秀明、角田拓実、陸美穂、池田洋、笠井謙次
- Organizer
  第105回日本病理学会総会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-16K19091
[Presentation] ヘッジホッグ系転写因子GLI1はCXCL12/CXCR4経路の活性化により乳癌細胞の遊走能を亢進させる2015
- Author(s)
  稲熊真悟、笠井謙次、伊藤秀明、陸美穂、池田洋
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-15K08358
[Presentation] 新規転写抑制因子TSHZ2からみた乳癌進展機構2015
- Author(s)
  陸美穂、笠井謙次、稲熊真悟、伊藤秀明、池田洋
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-15K08358
[Presentation] ヘッジホッグ系転写因子GLI1はCXCL12/CXCR4経路の活性化により乳癌細胞の遊走能を亢進させる
- Author(s)
  稲熊真悟、笠井謙次、伊藤秀明、陸美穂、池田洋
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-04-30 – 2015-05-02
- Data Source
  KAKENHI-PROJECT-24590456

1. KASAI Kenji (70242857)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. INAGUMA Shingo (80410786)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. IKEDA Hiroshi (00131219)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. SUZUKI Susumu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. SIVASUNDARAM Karnan

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 猪子誠人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 小川徹也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ito Hideaki 伊藤 秀明

ITO HIDEAKI 伊藤 秀明

ITO Hideaki 伊藤 秀明

Research Projects

Research Products

Co-Researchers

粘表皮癌におけるΔNp63陽性細胞先導による分子浸潤メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of tight junction attenuation by STIL and its application to the pathological diagnosis of ductal carcinoma in situ of the breastPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of STIL in invadopodia formation of pancreatic cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Downstream of newly identified transcriptional repressor and its role in the progression of non-invasive breast cancer.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Hedgehog signaling molecule SIL regulates the migration and progression of pancreatic ductal adenocarcinoma.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Establishment of Mucoepidermoid Carcinoma Cell Lines from Surgical and Recurrence Biopsy Specimens2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ENTREP/FAM189A2 encodes a new ITCH ubiquitin ligase activator that is downregulated in breast cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Indispensable role of STIL in the regulation of cancer cell motility through the lamellipodial accumulation of ARHGEF7-PAK1 complex2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Image cytometric detection and elucidation of proliferative capability of chromosome doubling cells2019

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] GLI1 orchestrates CXCR4/CXCR7 signaling to enhance migration and metastasis of breast cancer cells2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Down-regulation of the zinc-finger homeobox protein TSHZ2 releases GLI1 from the nuclear repressor complex to restore its transcriptional activity during mammary tumorigenesis2015

Author(s)

Journal Title

DOI

Data Source

[Patent] STIL-ARHGEF7シグナルの検出方法及びその使用2023

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Presentation] 中心小体複製因子STILによる細胞周期チェックポイント抑制によるアポトーシス回避2024

Author(s)

Organizer

Ito Hideaki 伊藤秀明

ITO HIDEAKI 伊藤秀明

ITO Hideaki 伊藤秀明