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Kawabata Reika  川端 麗香

ORCIDConnect your ORCID iD *help
Researcher Number 90721928
Other IDs
Affiliation (Current) 2022: 群馬大学, 未来先端研究機構, 講師
Affiliation (based on the past Project Information) *help 2018 – 2022: 群馬大学, 未来先端研究機構, 講師
2017: 群馬大学, 大学院医学系研究科, 助教
Review Section/Research Field
Principal Investigator
Genome biology / Basic Section 55020:Digestive surgery-related
Except Principal Investigator
Basic Section 48040:Medical biochemistry-related / Basic Section 53020:Cardiology-related / Basic Section 55040:Respiratory surgery-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 55020:Digestive surgery-related / Basic Section 58040:Forensics medicine-related / Basic Section 57060:Surgical dentistry-related
Keywords
Principal Investigator
新規治療標的 / 肺がん / トリプルネガティブ乳がん / 予後予測マーカー / 治療標的 / RNA-seq / 免疫組織染色 / バイオマーカー / 小細胞肺がん / 肺扁平上皮がん … More / 化学療法耐性機構 / 癌 / ゲノム / 遺伝子 / 膵がん / O-GlcNAc修飾 / KRAS / O-GlcNAc / 抗がん剤感受性 / 多階層オミクス解析 … More
Except Principal Investigator
エピゲノム / 遺伝性不整脈 / 遺伝性QT延長症候群 / Caチャネル / CACNA1C / 機能異常 / SCN5A / 遺伝性不整脈症候群 / 次世代シークエンス / 遺伝子変異 / イオンチャネル / 構造-機能連関 / FOXM1 / Chk1 / 小細胞肺癌 / ATR / MDR-1 / 抗がん剤耐性 / エピジェネティクス / ゲノム編集 / エピゲノム編集 / 子宮体癌 / 肥満 / エピトランスクリプトーム / 視床下部 / 形態病理 / 分化 / 肝がん / 突然死 / 脂肪肝 / 脂肪酸 / 代謝異常 / エクソーム / 生理活性脂質 / S1P / 炎症 / 近接ラベル化法 / 慢性炎症 / 受容体 / メトロノーム化学療法 Less
  • Research Projects

    (10 results)
  • Research Products

    (19 results)
  • Co-Researchers

    (33 People)
  •  肝がんの分化規定遺伝子の同定と革新的治療法の開発

    • Principal Investigator
      播本 憲史
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Gunma University
  •  Exome and lipidome analysis to elucidate the mechanisms of sudden death with hepatic steatosis

    • Principal Investigator
      高橋 遥一郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58040:Forensics medicine-related
    • Research Institution
      Gunma University
  •  The role of epigenome and epitranscriptome in the development of obesity

    • Principal Investigator
      河野 大輔
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Gunma University
  •  Regulation of chronic inflammation of blood vessels by a bioactive lipid mediator

    • Principal Investigator
      大日方 英
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Gunma University
  •  膵がん治療におけるO-GlcNAc分解酵素OGAの重要性とその分子機構の解明Principal Investigator

    • Principal Investigator
      川端 麗香
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Gunma University
  •  EphA4活性化により生じる高分化型口腔癌メトロノーム化学療法耐性機構の解明

    • Principal Investigator
      喜名 振一郎
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Gunma University
  •  次世代シークエンス及び電気生理学的手法を駆使した新規遺伝性不整脈の病態解明

    • Principal Investigator
      中島 忠
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Gunma University
  •  Elucidation of anticancer drug resistance mechanism of lung cancer through FOXM1

    • Principal Investigator
      大瀧 容一
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Gunma University
  •  Histone methyltransferase KMT2 mutation-induced epigenomic abnormalities and endometrial cancer development and progression

    • Principal Investigator
      畑田 出穂
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Gunma University
  •  Identification of novel biomarkers and therapeutic targets for refractory malignant solid tumors by comprehensive omics analysesPrincipal Investigator

    • Principal Investigator
      Kawabata Reika
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Genome biology
    • Research Institution
      Gunma University

All 2022 2021 2020 2019 2017

All Journal Article Presentation

  • [Journal Article] Robust Validation and Comprehensive Analysis of a Novel Signature Derived from Crucial Metabolic Pathways of Pancreatic Ductal Adenocarcinoma2022

    • Author(s)
      Gu Wenchao、Mo Shaocong、Wang Yulin、Kawabata-Iwakawa Reika、Zhang Wei、Yang Zongcheng、Sun Chenyu、Tsushima Yoshito、Xu Huaxiang、Nakajima Takahito
    • Journal Title

      Cancers

      Volume: 14 Pages: 1825-1825

    • DOI

      10.3390/cancers14071825

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08680
  • [Journal Article] Reduced current density, partially rescued by mexiletine, and depolarizing shift in activation of SCN5A W374G channels as a cause of severe form of Brugada syndrome2021

    • Author(s)
      Nakajima Tadashi、Dharmawan Tommy、Kawabata‐Iwakawa Reika、Tamura Shuntaro、Hasegawa Hiroshi、Kobari Takashi、Ota Masaki、Tange Shoichi、Nishiyama Masahiko、Kaneko Yoshiaki、Kurabayashi Masahiko
    • Journal Title

      Annals of Noninvasive Electrocardiology

      Volume: 26

    • DOI

      10.1111/anec.12828

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08487
  • [Journal Article] A molecular signature of well-differentiated oral squamous cell carcinoma reveals a resistance mechanism to metronomic chemotherapy and novel therapeutic candidates2021

    • Author(s)
      Kina S, Kawabata-Iwakawa R, Miyamoto S, Arasaki A, Sunakawa H, Kinjo T.
    • Journal Title

      J Drug Target .

      Volume: 29 Pages: 1118-1127

    • DOI

      10.1080/1061186x.2021.1929256

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08655, KAKENHI-PROJECT-21K10084
  • [Journal Article] Multiple arrhythmic and cardiomyopathic phenotypes associated with an SCN5A A735E mutation2021

    • Author(s)
      Sasaki Takashi、Ikeda Kentaro、Nakajima Tadashi、Kawabata-Iwakawa Reika、Iizuka Takashi、Dharmawan Tommy、Tamura Shuntaro、Niwamae Nogiku、Tange Shoichi、Nishiyama Masahiko、Kaneko Yoshiaki、Kurabayashi Masahiko
    • Journal Title

      Journal of Electrocardiology

      Volume: 65 Pages: 122-127

    • DOI

      10.1016/j.jelectrocard.2021.01.019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08487
  • [Journal Article] Gene Amplification-Associated Overexpression of the Selenoprotein tRNA Enzyme TRIT1 Confers Sensitivity to Arsenic Trioxide in Small-Cell Lung Cancer2021

    • Author(s)
      Coll-SanMartin Laia、Davalos Veronica、Pi?eyro David、Rossell?-Tortella Margalida、Bueno-Costa Alberto、Setien Fernando、Villanueva Alberto、Granada Isabel、Ruiz-Xiviller Neus、Kotter Annika、Helm Mark、Yokota Jun、Kawabata-Iwakawa Reika、Kohno Takashi、Esteller Manel
    • Journal Title

      Cancers

      Volume: 13 Pages: 1869-1869

    • DOI

      10.3390/cancers13081869

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15038
  • [Journal Article] Novel Cardiocerebral Channelopathy Associated with a <i>KCND3</i> V392I Mutation2020

    • Author(s)
      Nakajima Tadashi、Kawabata-Iwakawa Reika、Kaneko Yoshiaki、Hamano Shin-ichiro、Sano Rie、Tamura Shuntaro、Hasegawa Hiroshi、Kobari Takashi、Kominato Yoshihiko、Nishiyama Masahiko、Kurabayashi Masahiko
    • Journal Title

      International Heart Journal

      Volume: 61 Issue: 5 Pages: 1049-1055

    • DOI

      10.1536/ihj.20-203

    • NAID

      130007911359

    • ISSN
      1349-2365, 1349-3299
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08487, KAKENHI-PROJECT-20K21697, KAKENHI-PROJECT-19H03916
  • [Journal Article] Distinctive roles of syntaxin binding protein 4 and its action target, TP63, in lung squamous cell carcinoma: a theranostic study for the precision medicine2020

    • Author(s)
      Bilguun Erkhem-Ochir、Kaira Kyoichi、Kawabata-Iwakawa Reika、Rokudai Susumu、Shimizu Kimihiro、Yokobori Takehiko、Oyama Tetsunari、Shirabe Ken、Nishiyama Masahiko
    • Journal Title

      BMC Cancer

      Volume: 20 Pages: 935-935

    • DOI

      10.1186/s12885-020-07448-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15038
  • [Journal Article] Biophysical defects of an SCN5A V1667I mutation associated with epinephrine‐induced marked QT prolongation2020

    • Author(s)
      Nakajima Tadashi、Dharmawan Tommy、Kawabata‐Iwakawa Reika、Tamura Shuntaro、Hasegawa Hiroshi、Kobari Takashi、Kaneko Yoshiaki、Nishiyama Masahiko、Kurabayashi Masahiko
    • Journal Title

      Journal of Cardiovascular Electrophysiology

      Volume: 31 Pages: 2107-2115

    • DOI

      10.1111/jce.14575

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08487
  • [Journal Article] Carboxypeptidase A4 accumulation is associated with an aggressive phenotype and poor prognosis in triple-negative breast cancer.2019

    • Author(s)
      Handa Tadashi、Katayama Ayaka、Yokobori Takehiko、Yamane Arito、Fujii Takaaki、Obayashi Sayaka、Kurozumi Sasagu、Kawabata-Iwakawa Reika、Gombodorj Navchaa、Nishiyama Masahiko、Asao Takayuki、Shirabe Ken、Kuwano Hiroyuki、Oyama Tetsunari
    • Journal Title

      Int J Oncol.

      Volume: Mar;54(3) Pages: 833-844

    • DOI

      10.3892/ijo.2019.4675

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07665, KAKENHI-PROJECT-17K15038, KAKENHI-PROJECT-17K19893, KAKENHI-PROJECT-19K07456
  • [Journal Article] Stathmin-1 Is a Useful Diagnostic Marker for High-Grade Lung Neuroendocrine Tumors2019

    • Author(s)
      Shimizu Kimihiro、Goto Yusuke、Kawabata-Iwakawa Reika、Ohtaki Yoichi、Nakazawa Seshiru、Yokobori Takehiko、Obayashi Kai、Kawatani Natsuko、Yajima Toshiki、Kaira Kyoichi、Mogi Akira、Hirato Junko、Nishiyama Masahiko、Shirabe Ken
    • Journal Title

      The Annals of Thoracic Surgery

      Volume: 108 Pages: 235-243

    • DOI

      10.1016/j.athoracsur.2019.02.040

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15038
  • [Journal Article] Next-Generation Sequencing and Bioinformatics2017

    • Author(s)
      Kawabata-Iwakawa Reika、Bono Hidemasa、Nishiyama Masahiko
    • Journal Title

      Molecular Targeted Therapy of Lung Cancer

      Volume: - Pages: 97-115

    • DOI

      10.1007/978-981-10-2002-5_6

    • Data Source
      KAKENHI-PROJECT-17K15038
  • [Journal Article] High STMN1 Expression is Associated with Cancer Progression and Chemo-Resistance in Lung Squamous Cell Carcinoma2017

    • Author(s)
      Bao Pinjie、Yokobori Takehiko、Altan Bolag、Iijima Misaki、Azuma Youko、Onozato Ryoichi、Yajima Toshiki、Watanabe Akira、Mogi Akira、Shimizu Kimihiro、Nagashima Toshiteru、Ohtaki Yoichi、Obayashi Kai、Nakazawa Seshiru、Bai Tuya、Kawabata-Iwakawa Reika、Asao Takayuki、Kaira Kyoichi、Nishiyama Masahiko、Kuwano Hiroyuki
    • Journal Title

      Annals of Surgical Oncology

      Volume: 24 Pages: 4017-4024

    • DOI

      10.1245/s10434-017-6083-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K15038, KAKENHI-PROJECT-15K10085
  • [Journal Article] STXBP4 Drives Tumor Growth and Is Associated with Poor Prognosis through PDGF Receptor Signaling in Lung Squamous Cell Carcinoma2017

    • Author(s)
      Otaka Yukihiro、Rokudai Susumu、Kaira Kyoichi、Fujieda Michiru、Horikoshi Ikuko、Iwakawa-Kawabata Reika、Yoshiyama Shinji、Yokobori Takehiko、Ohtaki Yoichi、Shimizu Kimihiro、Oyama Tetsunari、Tamura Jun'ichi、Prives Carol、Nishiyama Masahiko
    • Journal Title

      Clinical Cancer Research

      Volume: 23 Pages: 3442-3452

    • DOI

      10.1158/1078-0432.ccr-16-1815

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15038
  • [Journal Article] Caspase14 expression is associated with triple negative phenotypes and cancer stem cell marker expression in breast cancer patients.2017

    • Author(s)
      Handa Tadashi、Katayama Ayaka、Yokobori Takehiko、Yamane Arito、Horiguchi Jun、Kawabata-Iwakawa Reika、Rokudai Susumu、Bao Pinjie、Gombodorj Navchaa、Altan Bolag、Kaira Kyoichi、Asao Takayuki、Kuwano Hiroyuki、Nishiyama Masahiko、Oyama Tetsunari
    • Journal Title

      J Surg Oncol.

      Volume: 116 Pages: 706-715

    • DOI

      10.1002/jso.24705

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K15038, KAKENHI-PROJECT-15K08339
  • [Journal Article] Significantly mutated genes and regulatory pathways in SCLC?a meta-analysis2017

    • Author(s)
      Sundaresan Varsha、Lin Victor T.、Liang Faming、Kaye Frederic J.、Kawabata-Iwakawa Reika、Shiraishi Kouya、Kohno Takashi、Yokota Jun、Zhou Lei
    • Journal Title

      Cancer Genetics

      Volume: 216-217 Pages: 20-28

    • DOI

      10.1016/j.cancergen.2017.05.003

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15038
  • [Journal Article] Myeloid sarcoma arising in malignant phyllodes tumour: clonal relationships revealed by comparative genome-wide analyses2017

    • Author(s)
      Arai Hideo、Nobusawa Sumihito、Kawabata-Iwakawa Reika、Rokudai Susumu、Higuchi Toru、Yamazaki Tatsuya、Horiguchi Jun、Sano Takaaki、Kojima Masaru、Nishiyama Masahiko、Yokoo Hideaki、Hirato Junko、Oyama Tetsunari
    • Journal Title

      British Journal of Haematology

      Volume: 181 Pages: 255-259

    • DOI

      10.1111/bjh.14539

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K15038
  • [Presentation] 失神を伴う痙攣発作の原因が異なる可能性がある若年姉妹例2022

    • Author(s)
      長谷川寛、中島忠、河内英行、川端麗香、田村峻太郎、小針尭司、西山正彦、倉林正彦、金古善明、石井秀樹
    • Organizer
      第2回日本不整脈心電学会関東甲信越支部地方会
    • Data Source
      KAKENHI-PROJECT-20K08487
  • [Presentation] Biophysical Defects of an SCN5A V1667I Mutation Associated with Epinephrine-Induced Marked QT Prolongation2022

    • Author(s)
      Tadashi Nakajima, Tommy Dharmawan, Reika Kawabata-Iwakawa, Shuntaro Tamura, Hiroshi Hasegawa, Takashi Kobari, Yoshiaki Kaneko, Masahiko Nishiyama, Masahiko Kurabayashi
    • Organizer
      第67回日本不整脈心電学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K08487
  • [Presentation] Utility of glycosylation regulation for pancreatic cancer treatment.2021

    • Author(s)
      Reika Kawabata, Hideru Obinata, Navchaa Gombodorj, Takehiko Yokobori
    • Organizer
      The 80th Annual Meeting of the Japanese Cancer Association
    • Data Source
      KAKENHI-PROJECT-21K08680
  • 1.  横堀 武彦 (60420098)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 2.  畑田 出穂 (50212147)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  大日方 英 (50332557)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 4.  西山 正彦 (20198526)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 5.  小林 良祐 (30802855)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  調 憲 (70264025)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  中島 忠 (40510574)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 8.  倉林 正彦 (00215047)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 9.  金古 善明 (60302478)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 10.  大瀧 容一 (00625402)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  矢島 俊樹 (20346852)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  堀居 拓郎 (00361387)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  森田 純代 (40589264)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  河野 大輔 (10382904)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  播本 憲史 (00419582)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  三森 功士 (50322748)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  伊古田 勇人 (90420116)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  高橋 遥一郎 (50640538)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  大嶋 紀安 (30360514)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  平野 瞳子 (20643810)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  窪 理英子 (40747127)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  佐野 利恵 (70455955)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 23.  早川 輝 (90758575)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  南嶋 洋司 (20593966)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  喜名 振一郎 (40422422)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 26.  金城 貴夫 (30284962)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 27.  喜名 美香 (80578914)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 28.  宮本 昇 (80749565)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 29.  FUJII Takaaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  YAMANE Arito
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  小湊 慶彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  桑野 博行
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 33.  小山 徹也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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