Kikkawa Takako 吉川貴子

Researcher Number	90727851
Other IDs
Affiliation (Current)	2025: 東北大学, 医学系研究科, 講師
Affiliation (based on the past Project Information) *help	2016 – 2024: 東北大学, 医学系研究科, 助教 2014 – 2016: 東北大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 48010:Anatomy-related / Morphology/Structure Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 48010:Anatomy-related / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / Basic Section 46010:Neuroscience-general-related / Developmental biology
Keywords	Principal Investigator 大脳皮質 / 神経幹細胞 / mRNA輸送 / 神経新生 / 進化 / 放射状グリア細胞 / 細胞分裂 / Kif23 / モータータンパク質 / 小頭症 … More / mRNA / 細胞周期因子 / RNA結合タンパク質 / ｍRNAの輸送 / 細胞周期 / CyclinD2 / Cyclin D2 … More Except Principal Investigator Pax6 / 性差 / FMRP / 神経発生 / 摂食行動 / 多価不飽和脂肪酸 / 集団飼育行動解析システム / 神経発達障害モデル / 遺伝子発現 / 加齢 / フェロトーシス / 性比 / 精子形成 / 脳計測科学 / 基盤・社会脳科学 / 脳科学 / 雄雌差 / 脳発生 / 雌雄差 / 大脳皮質発生 / 脆弱X症候群 / 標的遺伝子 / RNA結合タンパク / ニューロン新生 / 哺乳類大脳皮質 / Cyclin D2 / 大脳皮質 / 大脳新皮質 / 放射状グリア細胞 / 大脳皮質形成 / mRNA輸送 / 放射状グリア / RNA結合タンパク質 Less

Understanding sex differences in behavior and underlying neurodevelopmental mechanisms using mouse models of neurodevelopmental disorders
- Principal Investigator
  
  大隅典子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Tohoku University
Elucidation of the mechanism of microcephaly caused by motor protein dysfunction during brain developmentPrincipal Investigator
- Principal Investigator
  
  吉川貴子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Tohoku University
Elucidation of the molecular mechanism as to why the production of X sperm is less than that of Y sperm.
- Principal Investigator
  
  Osumi Noriko
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Tohoku University
妊娠中の脂肪酸摂取が仔の摂食行動を制御する新規メカニズムの解明
- Principal Investigator
  
  酒寄信幸
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Hiroshima University
A possible mechanism for enlargement of the cortex in placental mammals by the cellular mRNA transport systemPrincipal Investigator
- Principal Investigator
  
  Kikkawa Takako
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Tohoku University
Sex Differences in Pax6-FMRP Feedback Regulation Mechanisms in Neurogenesis
- Principal Investigator
  
  OSUMI Noriko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Tohoku University
Mechanism of RNA transport and localization in neural stem cells during corticogenesisPrincipal Investigator
- Principal Investigator
  
  Kikkawa Takako
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Tohoku University
Development of mRNA transportation mechanisms in neural stem/progenitor cells during evolutionPrincipal Investigator
- Principal Investigator
  
  Kikkawa Takako
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphology/Structure
- Research Institution
  Tohoku University
The role of RNA-binding protein for long-distance transportation of mRNA within embryonic neural progenitor cells
- Principal Investigator
  
  OSUMI Noriko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Developmental biology
- Research Institution
  Tohoku University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book Other

[Book] "Regulation of mRNA localization and translation in brain development: Implications for the mechanism leading to the brain evolution and pathogenesis" in Neocortical Neurogenesis in Development and Evolution2023
- Author(s)
  Takako Kikkawa, Sharmin Naher, Noriko Osumi.
- Total Pages
  15
- Publisher
  Wiley
- Data Source
  KAKENHI-PROJECT-23K06297
[Book] メディカル・サイエンス・ダイジェスト2023
- Author(s)
  吉川貴子、大隅典子
- Total Pages
  3
- Publisher
  ニュー・サイエンス社
- Data Source
  KAKENHI-PROJECT-23K06297
[Book] Electroporation Methods in Neuroscience2015
- Author(s)
  Takahashi M, Kikkawa T, Osumi N
- Total Pages
  199
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-26291046
[Journal Article] Investigating the impact of paternal aging on murine sperm miRNA profiles and their potential link to autism spectrum disorder2023
- Author(s)
  Miyahara Kazusa、Tatehana Misako、Kikkawa Takako、Osumi Noriko
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1
- DOI
  10.1038/s41598-023-47878-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06297, KAKENHI-PROJECT-22K19322
[Journal Article] Kinesin family member Kif23 regulates cytokinetic division and maintains neural stem/progenitor cell pool in the developing neocortex2023
- Author(s)
  Naher Sharmin、Kikkawa Takako、Iemura Kenji、Miyashita Satoshi、Hoshino Mikio、Tanaka Kozo、Niwa Shinsuke、Tsai Jin-Wu、Osumi Noriko
- Journal Title
  
  BioRxiv
  
  Volume: -
- DOI
  10.1101/2023.10.27.564302
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06297
[Journal Article] Regulation of male germline transmission patterns by the Trp53-Cdkn1a pathway2022
- Author(s)
  Kanatsu-Shinohara Mito、Naoki Honda、Tanaka Takashi、Tatehana Misako、Kikkawa Takako、Osumi Noriko、Shinohara Takashi
- Journal Title
  
  Stem Cell Reports
  
  Volume: 17 Issue: 9 Pages: 1924-1941
- DOI
  10.1016/j.stemcr.2022.07.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19322, KAKENHI-PROJECT-22K19429, KAKENHI-ORGANIZER-21H05167, KAKENHI-PROJECT-18H05281, KAKENHI-PROJECT-20J22054
[Journal Article] Deficiency of CHAMP1, a gene related to intellectual disability, causes impaired neuronal development and a mild behavioural phenotype2022
- Author(s)
  Masayoshi Nagai, Kenji Iemura, Takako Kikkawa, Noriko Osumi, Kozo Tanaka et al.
- Journal Title
  
  Brain Communications
  
  Volume: 4 Issue: 5
- DOI
  10.1093/braincomms/fcac220
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20K07237, KAKENHI-PROJECT-23K23877
[Journal Article] Thirty Years’ History since the Discovery of Pax6: From Central Nervous System Development to Neurodevelopmental Disorders2022
- Author(s)
  Ochi Shohei、Manabe Shyu、Kikkawa Takako、Osumi Noriko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 11 Pages: 6115-6115
- DOI
  10.3390/ijms23116115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19322, KAKENHI-PROJECT-20K07237, KAKENHI-PROJECT-21K15097
[Journal Article] Paternal age affects offspring via an epigenetic mechanism involving REST/NRSF.2021
- Author(s)
  Yoshizaki Kaichi, Kimura Ryuichi, Kobayashi Hisato, Oki Shinya, Kikkawa Takako, Mai Lingling, Koike Kohei, Mochizumi Kentaro, Inada Hitoshi, Matsui Yasuhisa, Kono Tomohiro, Osumi Noriko
- Journal Title
  
  EMBO Reports
  
  Volume: 22(2) Issue: 2
- DOI
  10.15252/embr.202051524
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08060, KAKENHI-PROJECT-20K07237, KAKENHI-PROJECT-19K18627, KAKENHI-INTERNATIONAL-16K21734, KAKENHI-ORGANIZER-16H06524, KAKENHI-PLANNED-16H06530, KAKENHI-PROJECT-19H03424, KAKENHI-PROJECT-18KT0024
[Journal Article] Autism-Related Transcription Factors Underlying the Sex-Specific Effects of Prenatal Bisphenol A Exposure on Transcriptome-Interactome Profiles in the Offspring Prefrontal Cortex2021
- Author(s)
  Kanlayaprasit Songphon、Thongkorn Surangrat、Panjabud Pawinee、Jindatip Depicha、Hu Valerie W.、Kikkawa Takako、Osumi Noriko、Sarachana Tewarit
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 24 Pages: 13201-13201
- DOI
  10.3390/ijms222413201
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-16K21734, KAKENHI-WRAPUP-21H00447, KAKENHI-PROJECT-19H03318, KAKENHI-PROJECT-20K07237
[Journal Article] Detection of <scp>REST</scp> expression in the testis using epitope‐tag knock‐in mice generated by genome editing2021
- Author(s)
  Kimura Ryuichi、U. Inoue Yukiko、Kikkawa Takako、Tatehana Misako、Morimoto Yuki、Inada Hitoshi、Oki Shinya、Inoue Takayoshi、Osumi Noriko
- Journal Title
  
  Developmental Dynamics
  
  Volume: 251 Issue: 3 Pages: 525-535
- DOI
  10.1002/dvdy.417
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18627, KAKENHI-INTERNATIONAL-16K21734, KAKENHI-PUBLICLY-19H04922, KAKENHI-WRAPUP-21H00447, KAKENHI-PROJECT-19H03318, KAKENHI-PROJECT-20J22054, KAKENHI-PROJECT-20K06467, KAKENHI-PROJECT-20K07237, KAKENHI-PROJECT-19H03424
[Journal Article] Sex differences in the effects of prenatal bisphenol A exposure on autism-related genes and their relationships with the hippocampus functions2021
- Author(s)
  Thongkorn Surangrat、Kanlayaprasit Songphon、Panjabud Pawinee、Saeliw Thanit、Jantheang Thanawin、Kasitipradit Kasidit、Sarobol Suthathip、Jindatip Depicha、Hu Valerie W.、Tencomnao Tewin、Kikkawa Takako、Sato Tatsuya、Osumi Noriko、Sarachana Tewarit
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1
- DOI
  10.1038/s41598-020-80390-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07237, KAKENHI-INTERNATIONAL-16K21734, KAKENHI-ORGANIZER-16H06524, KAKENHI-PLANNED-16H06530
[Journal Article] Multiple Functions of the Dmrt Genes in the Development of the Central Nervous System2021
- Author(s)
  Kikkawa Takako、Osumi Noriko
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 15 Pages: 789583-789583
- DOI
  10.3389/fnins.2021.789583
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03318, KAKENHI-PROJECT-20K07237
[Journal Article] Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis2020
- Author(s)
  Casingal Cristine R.、Kikkawa Takako、Inada Hitoshi、Sasaki Yukio、Osumi Noriko
- Journal Title
  
  Molecular Brain
  
  Volume: 13 Issue: 1 Pages: 1-13
- DOI
  10.1186/s13041-020-00706-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06877, KAKENHI-PROJECT-20K07237, KAKENHI-INTERNATIONAL-16K21734, KAKENHI-ORGANIZER-16H06524, KAKENHI-PLANNED-16H06530, KAKENHI-PROJECT-19H03318
[Journal Article] Chronic brain histamine depletion in adult mice induced depression-like behaviours and impaired sleep-wake cycle2020
- Author(s)
  Yamada Yo、Yoshikawa Takeo、Naganuma Fumito、Kikkawa Takako、Osumi Noriko、Yanai Kazuhiko
- Journal Title
  
  Neuropharmacology
  
  Volume: 175 Pages: 108179-108179
- DOI
  10.1016/j.neuropharm.2020.108179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06886, KAKENHI-PROJECT-20K07237, KAKENHI-PROJECT-19K16296
[Journal Article] Dmrt genes participate in the development of Cajal-Retzius cells derived from the cortical hem in the telencephalon.2020
- Author(s)
  Kikkawa, T., Sakayori, N., Yuuki, H., Katsuyama, Y., Matsuzaki, F., Konno, D., Abe, T., Kiyonari, H., Osumi, N.
- Journal Title
  
  Developmental Dynamics
  
  Volume: - Issue: 6 Pages: 698-710
- DOI
  10.1002/dvdy.156
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06530, KAKENHI-PROJECT-18K14999, KAKENHI-PROJECT-19K20184, KAKENHI-PUBLICLY-19H04791, KAKENHI-PUBLICLY-19H05023, KAKENHI-PROJECT-18K06502
[Journal Article] Paternal age affects offspring’s behavior possibly via an epigenetic mechanism recruiting a transcriptional repressor REST2019
- Author(s)
  Yoshizaki, K., Koike, T., Kimura, R., Kikkawa, T., Oki, S., Koike, K., Mochizuki, K., Inada, H., Kobayashi, H., Matsui, Y., Kono, T., Osumi, N.
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/550095
- Open Access
- Data Source
  KAKENHI-PROJECT-18K14999, KAKENHI-PROJECT-18KT0024
[Journal Article] Identification of FMRP target genes expressed in corticogenesis: implication for common phenotypes among neurodevelopmental disorders.2019
- Author(s)
  Casingal, C, R., Kikkawa, T., Inada, H., Osumi, N.
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/769026
- Open Access
- Data Source
  KAKENHI-PLANNED-16H06530, KAKENHI-PROJECT-18K14999
[Journal Article] The role of Pax6 in brain development and its impact on pathogenesis of autism spectrum disorder2018
- Author(s)
  Kikkawa Takako、Casingal Cristine R.、Chun Seung Hee、Shinohara Hiroshi、Hiraoka Kotaro、Osumi Noriko
- Journal Title
  
  Brain Research
  
  Volume: - Pages: 30111-2
- DOI
  10.1016/j.brainres.2018.02.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19372, KAKENHI-PROJECT-16K18983, KAKENHI-INTERNATIONAL-16K21734, KAKENHI-ORGANIZER-16H06524, KAKENHI-PLANNED-16H06530, KAKENHI-PROJECT-15K08127, KAKENHI-PROJECT-16K20902, KAKENHI-PROJECT-18K14999
[Journal Article] Conserved and divergent functions of Pax6 underlie species-specific neurogenic patterns in the developing amniote brain2018
- Author(s)
  Yamashita Wataru、Takahashi Masanori、Kikkawa Takako、Gotoh Hitoshi、Osumi Noriko、Ono Katsuhiko、Nomura Tadashi
- Journal Title
  
  Development
  
  Volume: 145 Issue: 8 Pages: 159764-159764
- DOI
  10.1242/dev.159764
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01394, KAKENHI-PROJECT-17H03552, KAKENHI-PROJECT-16J09444, KAKENHI-PROJECT-17K07079, KAKENHI-PROJECT-18K14999, KAKENHI-PLANNED-16H06530, KAKENHI-PROJECT-16K07031
[Journal Article] Organizing activity of Fgf8 on the anterior telencephalon.2017
- Author(s)
  Sato T, Kikkawa T, Saito T, Itoi K, Osumi N
- Journal Title
  
  Dev Growth Differ
  
  Volume: 59 Issue: 9 Pages: 701-712
- DOI
  10.1111/dgd.12411
- Peer Reviewed
- Data Source
  KAKENHI-INTERNATIONAL-16K21734, KAKENHI-ORGANIZER-16H06524, KAKENHI-PLANNED-16H06530, KAKENHI-PROJECT-16K15166, KAKENHI-PROJECT-16K20902
[Journal Article] Electroporation in the Rodent Embryonic Brain Using Whole Embryo Culture System.2017
- Author(s)
  Kikkawa T, Takahashi M, Osumi N
- Journal Title
  
  Curr Protoc Neurosci.
  
  Volume: 78 Issue: 1 Pages: 1-16
- DOI
  10.1002/cpns.21
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-16H06524, KAKENHI-PROJECT-26291046, KAKENHI-PROJECT-16K07031, KAKENHI-PROJECT-16K20902, KAKENHI-INTERNATIONAL-16K21734, KAKENHI-PLANNED-16H06530
[Journal Article] Regional volume decreases in the brain of Pax6 heterozygous mutant rats: MRI deformation-based morphometry2016
- Author(s)
  Hiraoka, K., Sumiyoshi, A., Nonaka, H., Kikkawa, T., Kawashima, R. and Osumi, N.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 6 Pages: e0158153-e0158153
- DOI
  10.1371/journal.pone.0158153
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26291046, KAKENHI-PROJECT-15K08127, KAKENHI-PROJECT-16K20902
[Journal Article] Gene tracing analysis reveals the contribution of neural crest-derived cells in pituitary development2016
- Author(s)
  Ueharu H, Yoshida S, Kikkawa T, Kanno N, Higuchi M, Kato T,　Osumi N,　Kato Y
- Journal Title
  
  Journal of Anatomy
  
  Volume: 230 Issue: 3 Pages: 373-380
- DOI
  10.1111/joa.12572
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15J11564, KAKENHI-PROJECT-26292166, KAKENHI-PROJECT-15K07771, KAKENHI-PROJECT-15K18801, KAKENHI-PROJECT-16K18818, KAKENHI-PROJECT-16K20902, KAKENHI-PROJECT-15J11568
[Journal Article] Preparation of rat serum suitable for mammalian whole embryo culture.2014
- Author(s)
  Takahashi M, Makino S, Kikkawa T, Osumi N.
- Journal Title
  
  J Vis Exp.
  
  Volume: 90 Issue: 90
- DOI
  10.3791/51969
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22123007, KAKENHI-PROJECT-24500373, KAKENHI-PROJECT-26291046
[Journal Article] Asymmetric inheritance of Cyclin D2 maintains proliferative neural stem/progenitor cells: a critical event in brain development and evolution.2014
- Author(s)
  Tsunekawa Y, Kikkawa T, Osumi N.
- Journal Title
  
  Dev Growth Differ.
  
  Volume: 522 Issue: 15 Pages: 3520-3528
- DOI
  10.1002/cne.23621
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22123007, KAKENHI-PROJECT-26291046
[Presentation] The function of N-Kinesin family motor protein in cytokinesis in neural stem cells during cortical development.2023
- Author(s)
  Naher, S., Kikkawa, T., Osumi, T.
- Organizer
  Society for Neuroscience 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06297
[Presentation] The age-associated sex chromosome ratio is altered in a Pax6 dependent manner2023
- Author(s)
  Germeraad, J., Tatehana, M., Inada, H., Kikkawa, T., Osumi, N.
- Organizer
  第128回日本解剖学会総会
- Data Source
  KAKENHI-PROJECT-22K19322
[Presentation] Cellular function of Kinesin family member Kif23 in neural stem/progenitor cells during cytokinesis.2023
- Author(s)
  Naher S., Kikkawa T., Osumi, T.
- Organizer
  第46回日本神経科学大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06297
[Presentation] The age-associated sex chromosome ratio is altered in a Pax6-dependent manner.2023
- Author(s)
  Germeraad, J, Tatehana, M, Inada H, Kikkawa, T, Osumi, N
- Organizer
  第16回リトリート東北大学大学院生研究発表会
- Data Source
  KAKENHI-PROJECT-22K19322
[Presentation] Age-related alteration of the sex chromosome ratio in round spermatids during spermatogenesis.2023
- Author(s)
  Germeraad, J, Tatehana, M., Inada H., Kikkawa, T., Osumi N
- Organizer
  第６回春の神経発生研究会
- Data Source
  KAKENHI-PROJECT-22K19322
[Presentation] 放射状グリア細胞内のmRNA-タンパク輸送ダイナミクスとその進化的意義2023
- Author(s)
  吉川貴子、若松義雄、井上-上野由紀子、鈴木久仁博、井上高良、大隅典子
- Organizer
  第128回日本解剖学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07237
[Presentation] The function of mitotic kinesin-like protein Kif23 in cytokinesis in neural stem/progenitor cells during cortical development.2023
- Author(s)
  Naher, S., Kikkawa, T., Osumi T.
- Organizer
  第56回日本発生生物学会大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06297
[Presentation] Ageing reduces the proportion of X carrying haploid male germline cells in a Pax6 dependent manner.2023
- Author(s)
  Germeraad J, Kikkawa T, Osumi N
- Organizer
  KU Leuven-Tohoku Univ Joint Symposium on Neuroscience
- Data Source
  KAKENHI-PROJECT-22K19322
[Presentation] The age-associated sex chromosome ratio is altered in a Pax6 dependent manner2023
- Author(s)
  Germeraad J, Kikkawa T, Osumi N
- Organizer
  第11回日本DOHaD学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19322
[Presentation] Pax6依存的な加齢に伴う性染色体比の変化2023
- Author(s)
  Germeraad J, 吉川貴子, 大隅典子
- Organizer
  先進ゲノム支援拡大班会議
- Data Source
  KAKENHI-PROJECT-22K19322
[Presentation] The age-associated sex chromosome ratio is altered in a Pax6 dependent manner.2023
- Author(s)
  Germeraad, J, Tatehana, M, Inada, H, Kikkawa, T, Osumi, N
- Organizer
  第128回日本解剖学会総会
- Data Source
  KAKENHI-PROJECT-22K19322
[Presentation] 有胎盤類特有のzip code配列獲得による放射状グリア細胞内mRNA輸送機構の進化2022
- Author(s)
  吉川貴子、若松義雄、井上-上野由紀子、鈴木久仁博、井上高良、大隅典子
- Organizer
  第127回日本解剖学会
- Data Source
  KAKENHI-PROJECT-20K07237
[Presentation] Basal transport of Ccnd2 mRNA in radial glial cells is important for the production of basal progenitors in the developing mouse cortex2022
- Author(s)
  Kikkawa, T., Wakamatsu, Y., Inoue, YU., Inoue, T., Osumi, N.
- Organizer
  24th Biennial Meeting of the International Society for Developmental Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07237
[Presentation] Age-associated sex chromosome ratio alteration through Pax6-dependent ferroptosis2022
- Author(s)
  Germeraad, J., Tatehana, M., Inada, H., Kikkawa, T., Osumi, N.
- Organizer
  IROS&F in Life, Death & Disease.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19322
[Presentation] Evolution of an mRNA transport mechanism in radial glial cells by acquisition of a unique zip code sequence in placental mammals2022
- Author(s)
  Kikkawa, T., Wakamatsu, Y., Inoue, YU., Suzuki, K., Inoue, T., Osumi, N.
- Organizer
  第44回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20K07237
[Presentation] Paternal aging and the offspring sex ratio in mice2022
- Author(s)
  Osumi, N., Tatehana, M., Inada H., Kikkawa, T.
- Organizer
  DOHaD国際学会2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19322
[Presentation] Age-associated sex chromosome ratio alteration through Pax6-dependent ferroptosis2022
- Author(s)
  Germeraad, J., Tatehana, M., Inada, H., Kikkawa, T., Osumi, N.
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-22K19322
[Presentation] Identification of FMRP mRNA targets during corticogenesis2021
- Author(s)
  Cristine R. Casingal, Takako Kikkawa, Hitoshi Inada, Noriko Osumi
- Organizer
  第14回神経発生討論会
- Data Source
  KAKENHI-PROJECT-19H03318
[Presentation] Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate mTOR signaling during corticogenesis.2021
- Author(s)
  Kikkawa, T., Casingal, RC, Inoue, YU., Ebrahimiazar, S, Inada, H., Osumi, N.
- Organizer
  7th Congress of AsCNP
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07237
[Presentation] Investigation of the role of gender difference in FMRP mRNA targets during corticogenesis2021
- Author(s)
  Sara Ebrahimiazar, Takako Kikkawa, Noriko Osumi
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19H03318
[Presentation] Identification of motor proteins mediating basal transport of mRNA of a cell cycle regulator Cyclin D2 in the neural stem/progenitor cells.2021
- Author(s)
  Sharmin Naher, Takako Kikkawa, Noriko Osumi
- Organizer
  23rd Biennial Meeting of the International Society of Developmental Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03318
[Presentation] Transport mechanisms of Cyclin D2 mRNA and protein along the basal process of neural stem/progenitor cells of the developing brain.2021
- Author(s)
  Kikkawa, T., Wakamatsu, Y., Inoue, YU., Inoue, T., Osumi, N.
- Organizer
  第44回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20K07237
[Presentation] Identification of motor proteins mediating basal transport of Cyclin D2 mRNA in the neural stem/progenitor cells.2021
- Author(s)
  Sharmin Naher, Takako Kikkawa, Noriko Osumi
- Organizer
  The 80th Fujiwara seminar “Molecular and cellular mechanisms of brain systems generating individuality”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03318
[Presentation] Cyclin D2 mRNA and protein transport along the basal process of radial glial cells during brain development.2021
- Author(s)
  Kikkawa, T., Wakamatsu, Y., Inoue, YU., Inoue, T., Osumi, N.
- Organizer
  The 80th Fujiwara seminar “Molecular and cellular mechanisms of brain systems generating individuality”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07237
[Presentation] Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate mTOR signaling during corticogenesis.2021
- Author(s)
  Takako Kikkawa, Cristine R. Casingal, Yukiko U. Inoue, Sara Ebrahimiazar, Hitoshi Inada, Noriko Osumi
- Organizer
  7th Congress of AsCNP
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03318
[Presentation] Analysis of mRNA transport mechanisms of a cell cycle regulator Cyclin D2 in radial glial cells: a possible mechanism of enlargement of the cortex in placental mammals.2021
- Author(s)
  Kikkawa, T., Wakamatsu, Y. Inoue U, Kunihiro Suzuki, Inoue, T., Osumi, N.
- Organizer
  第126回日本解剖学会
- Data Source
  KAKENHI-PROJECT-20K07237
[Presentation] 放射状グリア細胞における細胞周期因子Cyclin D2のmRNA輸送機構の解析：有胎盤類の大脳皮質拡大に寄与する可能性2021
- Author(s)
  吉川貴子、若松義雄、井上-上野由紀子、鈴木久仁博、井上高良、大隅典子
- Organizer
  日本解剖学会第67回東北・北海道連合支部学術集会
- Data Source
  KAKENHI-PROJECT-20K07237
[Presentation] Identification of FMRP target genes expressed during corticogenesis2020
- Author(s)
  Cristine R. Casingal, Takako Kikkawa, Hitoshi Inada, Noriko Osumi
- Organizer
  NPBPPP 2020合同年会
- Data Source
  KAKENHI-PROJECT-19H03318
[Presentation] 胎生期の神経前駆細胞内におけるmRNA調節メカニズム2020
- Author(s)
  吉川貴子、Cristine Casingal、Sharmin Naher、井上-上野由紀子、井上高良、大隅典子
- Organizer
  NPBPPP 2020合同年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07237
[Presentation] Transport mechanisms of Cyclin D2 mRNA along the basal process of neural stem/progenitor cells of the developing brain.2020
- Author(s)
  Kikkawa, T., Wakamatsu, Y. Inoue U, Inoue, T., Osumi, N.
- Organizer
  EMBO | EMBL Symposium: The Complex Life of RNA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07237
[Presentation] Enhanced mTOR signaling activity in Fmr1 knockout embryonic brain during corticogenesis2020
- Author(s)
  Cristine R. Casingal, Takako Kikkawa, Hitoshi Inada, Noriko Osumi
- Organizer
  新学術領域研究「個性」創発脳第5回領域会議
- Data Source
  KAKENHI-PROJECT-19H03318
[Presentation] CyclinD2のmRNA輸送による有胎盤類大脳皮質の拡大機構の解明2020
- Author(s)
  吉川貴子、若松義雄、井上-上野由紀子、鈴木久仁博、井上高良、大隅典子
- Organizer
  125回日本解剖学会
- Data Source
  KAKENHI-PROJECT-18K14999
[Presentation] mRNA transport of Cyclin D2 in radial glial cells during brain development.2020
- Author(s)
  Kikkawa, T.
- Organizer
  The 5th German-Japanize Retreat on Forebrain Development
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14999
[Presentation] mRNA transport mechanism of a cell cycle regulator Cyclin D2 in neural stem/progenitor cells during corticogenesis.2019
- Author(s)
  Kikkawa, T., Wakamatsu, Y. Inoue U, Y., Tsunekawa, Y., Matsuzaki, F., Suzuki, K., Inoue, T., Osumi, N.
- Organizer
  20th TMIMS International Symposium “Principles of Neocortical Development and Evolution”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14999
[Presentation] Analyses of Cyclin D2 mRNA transport mechanism in radial glial cells during corticogenesis.2019
- Author(s)
  Kikkawa, T., Inoue U, Y., Inoue, T., Osumi, N.
- Organizer
  第12回神経発生討論会
- Data Source
  KAKENHI-PROJECT-18K14999
[Presentation] mRNA transport mechanism of a cell cycle regulator Cyclin D2 in neural stem/progenitor cells during corticogenesis.2019
- Author(s)
  Kikkawa, T., Wakamatsu, Y. Inoue U, Y., Tsunekawa, Y., Matsuzaki, F., Suzuki, K., Inoue, T., Osumi, N.
- Organizer
  次世代脳プロジェクト冬のシンポジウム2019
- Data Source
  KAKENHI-PROJECT-18K14999
[Presentation] mRNA transport mechanism of a cell cycle regulator Cyclin D2 in neural stem/progenitor cells during corticogenesis.2019
- Author(s)
  Kikkawa, T., Wakamatsu, Y. Inoue U, Y., Tsunekawa, Y., Matsuzaki, F., Suzuki, K., Inoue, T., Osumi, N.
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K14999
[Presentation] Dmrt genes control the development of Cajal-Retzius cells derived from specific origins in the cerebral cortex.2018
- Author(s)
  Kikkawa, T., Sakayori, N., Yuuki, H., Osumi, N.
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K14999
[Presentation] Analyses of Cyclin D2 mRNA transportation mechanism in radial glial cells during corticogenesis.2018
- Author(s)
  Kikkawa, T., Inoue U, Y., Inoue, T., Osumi, N.
- Organizer
  Special Lecture on the 5th Anniversary of the Tohoku Forum for Creativity “Genome Editing”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14999
[Presentation] Analyses of Cyclin D2 mRNA transportation mechanism in radial glial cells during corticogenesis.2018
- Author(s)
  Kikkawa, T., Inoue U, Y., Inoue, T., Osumi, N.
- Organizer
  22th Biennial Meeting of the International Society for Developmental Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14999
[Presentation] Analyses of Cyclin D2 mRNA transportation mechanism in neural stem/progenitor cells during cortical development.2017
- Author(s)
  Kikkawa, T., Inoue U, Y., Inoue, T., Osumi, N.
- Organizer
  第13回成体脳のニューロン新生懇談会
- Data Source
  KAKENHI-PROJECT-16K20902
[Presentation] Analyses of Cyclin D2 mRNA transportation in the cortical development using CRISPR/Cas9 genome editing system.2017
- Author(s)
  Kikkawa, T., Inoue U, Y., Inoue, T., Osumi, N.
- Organizer
  第10回神経発生討論会
- Place of Presentation
  韓国・仁川
- Year and Date
  2017-03-10
- Data Source
  KAKENHI-PROJECT-16K20902
[Presentation] Analyses of Cyclin D2 mRNA transportation mechanism in ragial glial cells during corticogenesis using CRISPR/Cas9 genome editing system.2017
- Author(s)
  Kikkawa, T., Inoue U, Y., Inoue, T., Osumi, N.
- Organizer
  第40回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K20902
[Presentation] Analyses of Cyclin D2 mRNA transportation in the cortical development using CRISPR/Cas9 genome editing system.2017
- Author(s)
  Kikkawa, T., Inoue U, Y., Inoue, T., Osumi, N.
- Organizer
  第60回日本神経化学会
- Data Source
  KAKENHI-PROJECT-16K20902
[Presentation] Dmrt genes regulate Cajal-Retzius cell development of the cerebral cortex.2016
- Author(s)
  Kikkawa, T., Sakayori, N., Yuuki, H., Osumi, N.
- Organizer
  第9回神経発生討論会
- Place of Presentation
  東京、東京医科歯科大学
- Year and Date
  2016-03-19
- Data Source
  KAKENHI-PROJECT-26291046
[Presentation] Analyses of Cyclin D2 mRNA transportation in the cortical development using CRISPR/Cas9 genome editing system.2016
- Author(s)
  Kikkawa, T., Inoue U, Y., Inoue, T., Casingal R, C., Osumi, N.
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  横浜・パシフィコ横浜
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-16K20902
[Presentation] Cyclin D2 mRNA transportation in the cortical development is based on the 3’ UTR element: a CRISPR/Cas9 analysis.2016
- Author(s)
  Kikkawa, T., Inoue U, Y., Inoue, T., Osumi, N.
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  横浜・パシフィコ横浜
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-16K20902
[Presentation] Pax6 is involved in the development of cortical Sp8 positive inhibitory cells2016
- Author(s)
  Nakamura, R., Kikkawa, T., Sato, T., Osumi, N.
- Organizer
  第9回神経発生討論会
- Place of Presentation
  東京、東京医科歯科大学
- Year and Date
  2016-03-19
- Data Source
  KAKENHI-PROJECT-26291046
[Presentation] Dmrt genes differentially participate in Cajal-Retzius cell development of the cerebral cortex.2016
- Author(s)
  Kikkawa, T., Sakayori, N., Yuuki, H., Katsuyama, Y., Osumi, N.
- Organizer
  Neocortical Organization III
- Place of Presentation
  東京、東京大学
- Year and Date
  2016-02-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291046
[Presentation] Dmrt genes differentially participate in Cajal-Retzius cell development of the cerebral cortex.2015
- Author(s)
  Kikkawa, T., Sakayori, N., Yuuki, H., Kastuyama, Y., Osumi, N.
- Organizer
  Tohoku Forum for Creativity, Development and Disease
- Place of Presentation
  仙台、東北大学
- Year and Date
  2015-08-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291046
[Presentation] Pax6 is involved in inhibitory neuron production in the murine cerebral cortex2015
- Author(s)
  Nakamura, R., Kikkawa, T., Sato, T., Osumi, N.
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸、神戸ポートアイランド
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-26291046
[Presentation] Dmrt genes differentially participate in Cajal-Retzius cell development of the cerebral cortex.2015
- Author(s)
  Kikkawa, T., Sakayori, N., Yuuki, H., Katsuyama, Y., Osumi, N.
- Organizer
  Society for Neuroscience 45th Annual Meeting
- Place of Presentation
  アメリカ・シカゴ
- Year and Date
  2015-10-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291046
[]

1. OSUMI Noriko (00220343)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. 稲田仁 (60419893)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
3. 若松義雄 (60311560)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. 越智翔平 (30884217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 酒寄信幸 (30747457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 有田誠 (80292952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YOSHIZAKI Kaichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. YOSHIKAWA Takeo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 山下典子

# of Collaborated Projects: 0 results

# of Collaborated Products: 36 results
10. 野村真

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 佐々木幸生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 木村龍一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kikkawa Takako 吉川 貴子

Research Projects

Research Products

Co-Researchers

Understanding sex differences in behavior and underlying neurodevelopmental mechanisms using mouse models of neurodevelopmental disorders

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Elucidation of the mechanism of microcephaly caused by motor protein dysfunction during brain developmentPrincipal Investigator

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Elucidation of the molecular mechanism as to why the production of X sperm is less than that of Y sperm.

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妊娠中の脂肪酸摂取が仔の摂食行動を制御する新規メカニズムの解明

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A possible mechanism for enlargement of the cortex in placental mammals by the cellular mRNA transport systemPrincipal Investigator

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Sex Differences in Pax6-FMRP Feedback Regulation Mechanisms in Neurogenesis

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Mechanism of RNA transport and localization in neural stem cells during corticogenesisPrincipal Investigator

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Development of mRNA transportation mechanisms in neural stem/progenitor cells during evolutionPrincipal Investigator

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The role of RNA-binding protein for long-distance transportation of mRNA within embryonic neural progenitor cells

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[Book] "Regulation of mRNA localization and translation in brain development: Implications for the mechanism leading to the brain evolution and pathogenesis" in Neocortical Neurogenesis in Development and Evolution2023

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[Book] メディカル・サイエンス・ダイジェスト2023

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[Book] Electroporation Methods in Neuroscience2015

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[Journal Article] Investigating the impact of paternal aging on murine sperm miRNA profiles and their potential link to autism spectrum disorder2023

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[Journal Article] Kinesin family member Kif23 regulates cytokinetic division and maintains neural stem/progenitor cell pool in the developing neocortex2023

Author(s)

Kikkawa Takako 吉川貴子