Uneda Kazushi 畝田一司

Researcher Number	90780370
Other IDs
Affiliation (Current)	2025: 福島県立医科大学, 公私立大学の部局等, 准教授 2025: 横浜市立大学, 医学研究科, 客員研究員
Affiliation (based on the past Project Information) *help	2019 – 2021: 横浜市立大学, 医学研究科, 客員研究員 2017 – 2018: 横浜市立大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Kidney internal medicine Except Principal Investigator Basic Section 52010:General internal medicine-related
Keywords	Principal Investigator AT1受容体 / ATRAP / レニン・アンジオテンシン系 / レニンアンジオテンシン系 / 糖尿病 / 白血球 / マクロファージ / 1型アンジオテンシン受容体 / 循環器・高血圧 / アンジオテンシンII / 慢性腎臓病 / 高血圧 / 腎内レニン・アンジオテンシン系 … More Except Principal Investigator … More 新規治療 / 腎性老化 / 高血圧 / 治療標的 / 病態解明 / 腎臓病・高血圧 / 受容体 / 情報伝達系 Less

Pathophysiological significance of angiotensin receptor-binding protein in leucocytes and immune cellsPrincipal Investigator
- Principal Investigator
  
  UNEDA Kazushi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Yokohama City University
Therapeutic Strategy against Renal Aging via Novel Dual Actions of Receptor-binding Molecule
- Principal Investigator
  
  TAMURA Kouichi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Yokohama City University
Pathophygiological Investigations of ATRAP in Renal Tubules on Kidney InjuryPrincipal Investigator
- Principal Investigator
  
  Uneda Kazushi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Yokohama City University

All 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Deficiency of the kidney tubular angiotensin II type1 receptor?associated protein ATRAP exacerbates streptozotocin-induced diabetic glomerular injury via reducing protective macrophage polarization2022
- Author(s)
  Haruhara Kotaro、Suzuki Toru、Wakui Hiromichi、Azushima Kengo、Kurotaki Daisuke、Kawase Wataru、Uneda Kazushi、Kobayashi Ryu、Ohki Kohji、Kinguchi Sho、Yamaji Takahiro、Kato Ikuma、Ohashi Kenichi、Yamashita Akio、Tamura Tomohiko、Tsuboi Nobuo、Yokoo Takashi、Tamura Kouichi
- Journal Title
  
  Kidney International
  
  Volume: 101 Issue: 5 Pages: 912-928
- DOI
  10.1016/j.kint.2022.01.031
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-19K17575, KAKENHI-PROJECT-20K22908, KAKENHI-PROJECT-20H03438, KAKENHI-PROJECT-20K07786, KAKENHI-PROJECT-21K19413, KAKENHI-PROJECT-21K16166, KAKENHI-PROJECT-22K20890, KAKENHI-PROJECT-20K21606, KAKENHI-PROJECT-21H02954
[Journal Article] Comparison of effects of SGLT-2 inhibitors and GLP-1 receptor agonists on cardiovascular and renal outcomes in type 2 diabetes mellitus patients with/without albuminuria: A systematic review and network meta-analysis2022
- Author(s)
  Kawai Yuki、Uneda Kazushi、Yamada Takayuki、Kinguchi Sho、Kobayashi Kazuo、Azushima Kengo、Kanaoka Tomohiko、Toya Yoshiyuki、Wakui Hiromichi、Tamura Kouichi
- Journal Title
  
  Diabetes Research and Clinical Practice
  
  Volume: 183 Pages: 109146-109146
- DOI
  10.1016/j.diabres.2021.109146
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08730, KAKENHI-PROJECT-19K17575, KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-20K07786, KAKENHI-PROJECT-20K21606
[Journal Article] Systematic review and meta-analysis for prevention of cardiovascular complications using GLP-1 receptor agonists and SGLT-2 inhibitors in obese diabetic patients2021
- Author(s)
  Uneda Kazushi、Kawai Yuki、Yamada Takayuki、Kinguchi Sho、Azushima Kengo、Kanaoka Tomohiko、Toya Yoshiyuki、Wakui Hiromichi、Tamura Kouichi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 10166-10166
- DOI
  10.1038/s41598-021-89620-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08730, KAKENHI-PROJECT-19K17575, KAKENHI-PROJECT-20K07786
[Journal Article] Prevention of kidney function decline using uric acid-lowering therapy in chronic kidney disease patients: a systematic review and network meta-analysis2021
- Author(s)
  Tsukamoto Shunichiro、Okami Naohito、Yamada Takayuki、Azushima Kengo、Yamaji Takahiro、Kinguchi Sho、Uneda Kazushi、Kanaoka Tomohiko、Wakui Hiromichi、Tamura Kouichi
- Journal Title
  
  Clinical Rheumatology
  
  Volume: 41 Issue: 3 Pages: 911-919
- DOI
  10.1007/s10067-021-05956-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08730, KAKENHI-PROJECT-19K17575, KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-20K07786, KAKENHI-PROJECT-20K21606
[Journal Article] Aristolochic Acid Induces Renal Fibrosis and Senescence in Mice2021
- Author(s)
  Urate Shingo、Wakui Hiromichi、Azushima Kengo、Yamaji Takahiro、Suzuki Toru、Abe Eriko、Tanaka Shohei、Taguchi Shinya、Tsukamoto Shunichiro、Kinguchi Sho、Uneda Kazushi、Kanaoka Tomohiko、Atobe Yoshitoshi、Funakoshi Kengo、Yamashita Akio、Tamura Kouichi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 22 Pages: 12432-12432
- DOI
  10.3390/ijms222212432
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08730, KAKENHI-PROJECT-19K17575, KAKENHI-PROJECT-20K07786, KAKENHI-PROJECT-21K19413
[Journal Article] Effects of Rikkunshito treatment on renal fibrosis/inflammation and body weight reduction in a unilateral ureteral obstruction model in mice2020
- Author(s)
  Wakui H, Yamaji T, Azushima K, Uneda K, Haruhara K, Nakamura A, Ohki K, Kinguchi S, Kobayashi R, Urate S, Suzuki T, Kamimura D, Minegishi S, Ishigami T, Kanaoka T, Matsuo K, Miyazaki T, Fujikawa T, Yamashita A, Tamura K.
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1782-1782
- DOI
  10.1038/s41598-020-58214-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-19K17575, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-19K21318, KAKENHI-PROJECT-19K08730, KAKENHI-PROJECT-20K07786
[Journal Article] Angiotensin II type 1 receptor-associated protein deficiency attenuates sirtuin1 expression in an immortalised human renal proximal tubule cell line2019
- Author(s)
  Yamaji T, Yamashita A, Wakui H, Azushima K, Uneda K, Fujikawa Y, Haku S, Kobayashi R, Ohki K, Haruhara K, Kinguchi S, Ishii T, Yamada T, Urate S, Suzuki T, Abe E, Tanaka S, Kamimura D, Ishigami T, Toya Y, Takahashi H, Tamura K.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 16550-16550
- DOI
  10.1038/s41598-019-52566-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-19K17575, KAKENHI-PROJECT-19K18010, KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-19K21318
[Journal Article] Effects of ATRAP in Renal Proximal Tubules on Angiotensin‐Dependent Hypertension2019
- Author(s)
  Kinguchi Sho、Wakui Hiromichi、Azushima Kengo、Haruhara Kotaro、Koguchi Tomoyuki、Ohki Kohji、Uneda Kazushi、Matsuda Miyuki、Haku Sona、Yamaji Takahiro、Yamada Takayuki、Kobayashi Ryu、Minegishi Shintaro、Ishigami Tomoaki、Yamashita Akio、Fujikawa Tetsuya、Tamura Kouichi
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 8 Issue: 8
- DOI
  10.1161/jaha.119.012395
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-17H06993, KAKENHI-PROJECT-17K19665, KAKENHI-PROJECT-17K16091, KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-19K17575, KAKENHI-PROJECT-19K18010, KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-19K21318
[Journal Article] Effects of rikkunshito on renal fibrosis and inflammation in angiotensin II-infused mice2019
- Author(s)
  Azushima Kengo、Uneda Kazushi、Wakui Hiromichi、Ohki Kohji、Haruhara Kotaro、Kobayashi Ryu、Haku Sona、Kinguchi Sho、Yamaji Takahiro、Minegishi Shintaro、Ishigami Tomoaki、Yamashita Akio、Tamura Kouichi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 6201-6201
- DOI
  10.1038/s41598-019-42657-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-17H06993, KAKENHI-PROJECT-17K19665, KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-19K17575, KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-19K21318
[Journal Article] Angiotensin receptor-binding molecule in leukocytes in association with the systemic and leukocyte inflammatory profile2018
- Author(s)
  Haruhara Kotaro、Wakui Hiromichi、Azushima Kengo、Kurotaki Daisuke、Kawase Wataru、Uneda Kazushi、Haku Sona、Kobayashi Ryu、Ohki Kohji、Kinguchi Sho、Ohsawa Masato、Minegishi Shintaro、Ishigami Tomoaki、Matsuda Miyuki、Yamashita Akio、Nakajima Hideaki、Tamura Tomohiko、Tsuboi Nobuo、Yokoo Takashi、Tamura Kouichi
- Journal Title
  
  Atherosclerosis
  
  Volume: 269 Pages: 236-244
- DOI
  10.1016/j.atherosclerosis.2018.01.013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19665, KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-15H04331, KAKENHI-PROJECT-17H06993, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-16K09647, KAKENHI-PROJECT-17K09730
[Journal Article] Angiotensin II Type 1 Receptor-associated Protein Inhibits Angiotensin II-induced Insulin Resistance with Suppression of Oxidative Stress in Skeletal Muscle Tissue2018
- Author(s)
  Ohki Kohji、Wakui Hiromichi、Kishio Nozomu、Azushima Kengo、Uneda Kazushi、Haku Sona、Kobayashi Ryu、Haruhara Kotaro、Kinguchi Sho、Yamaji Takahiro、Yamada Takayuki、Minegishi Shintaro、Ishigami Tomoaki、Toya Yoshiyuki、Yamashita Akio、Imajo Kento、Nakajima Atsushi、Kato Ikuma、Ohashi Kenichi、Tamura Kouichi
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 2846-2846
- DOI
  10.1038/s41598-018-21270-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19665, KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-15H04331, KAKENHI-PROJECT-17H06993, KAKENHI-PROJECT-16K19558, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-19K21318
[Journal Article] Early Enhanced Leucine-Rich α-2-Glycoprotein-1 Expression in Glomerular Endothelial Cells of Type 2 Diabetic Nephropathy Model Mice2018
- Author(s)
  haku Sona、Wakui Hiromichi、Azushima Kengo、Haruhara Kotaro、Kinguchi Sho、Ohki Kohji、Uneda Kazushi、Kobayashi Ryu、Matsuda Miyuki、Yamaji Takahiro、Yamada Takayuki、Minegishi Shintaro、Ishigami Tomoaki、Yamashita Akio、Ohashi Kenichi、Tamura Kouichi
- Journal Title
  
  BioMed Research International
  
  Volume: 2018 Pages: 1-9
- DOI
  10.1155/2018/2817045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09313, KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-18H02735, KAKENHI-PROJECT-17K19665, KAKENHI-PROJECT-17K09730
[Presentation] 漢方薬「六君子湯」による腎保護効果の検討2019
- Author(s)
  畝田一司, 小豆島健護, 涌井広道, 大城光二, 春原浩太郎, 小林竜, 金口翔, 山地孝拡, 浦手進吾, 田村功一
- Organizer
  第62回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-19K17575
[Presentation] 腎近位尿細管AT1受容体結合因子がアンジオテンシン依存性高血圧に及ぼす影響(Effects of AT1 Receptor-Associated Protein in Renal Proximal Tubules on Angiotensin II-Mediated Hypertension)2019
- Author(s)
  金口翔, 涌井広道, 小豆島健護, 春原浩太郎, 高口知之, 大城光二, 畝田一司, 白善雅, 山地孝拡, 山田貴之, 小林竜, 石上友章, 山下暁朗, 藤川哲也, 田村功一
- Organizer
  第42回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-19K17575
[Presentation] An emerging role of angiotensin receptor binding protein ATRAP as a possible novel player in pathophysiology of visceral obesity and metabolic disorders.2018
- Author(s)
  ouichi Tamura, Kohji Ohki, Kengo Azushima, Kazushi Uneda, Ryu Kobayashi, Sho Kinguchi, Kotaro Haruhara, Takahiro Yamaji, Takayuki Yamada, Hiromichi Wakui.
- Organizer
  Symposium 73, WCP2018 Kyoto: New perspectives on the function and pharmacology of the renin-angiotensin system. The 18th World Congress of Basic and Clinical Pharmacology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02735
[Presentation] Novel Receptor Binding Protein ATRAP in the Regulation of Renal Sodium Reabsorption and Blood Pressure Response.2018
- Author(s)
  Kouichi Tamura, Ryu Kobayashi, Kengo Azushima, Kazushi Uneda, Sona Haku, Kohji Ohki, Kotaro Haruhara, Sho Kinguchi, Masato Ohsawa, Shin-ichiro Masuda, Miyuki Matsuda, Akio Yamashita, Hiromichi Wakui.
- Organizer
  Technical Session 1A: Salt and Cardiovascular Health. World Salt Symposium 2018: Salt of the Earth
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02735
[Presentation] Proximal tubule Angiotensin II Type 1 Receptor-associated Protein Regulates Kidney Aging and Lifespan through Sirtuin1-mediated Pathway.2018
- Author(s)
  17.Takahiro Yamaji, Kazushi Uneda, Shingo Urate, Takayuki Yamada, Sho Kinguchi, Sona Haku, Kotaro Haruhara, Kohji Ohki, Ryu Kobayashi, Kengo Azushima, Hiromichi Wakui, Yoshiyuki Toya, Akio Yamashita, Kouichi Tamura.
- Organizer
  The 51th Annual Meeting & Scientific Exposition of American Society of Nephrology (ASN Kidney Week 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02735

1. TAMURA Kouichi (40285143)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
2. 涌井広道 (10587330)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. 山下暁朗 (20405020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
4. 小林竜 (60805612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. Kinguchi Sho

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KANAOKA Tomohiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

Uneda Kazushi 畝田 一司

Research Projects

Research Products

Co-Researchers

Pathophysiological significance of angiotensin receptor-binding protein in leucocytes and immune cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Therapeutic Strategy against Renal Aging via Novel Dual Actions of Receptor-binding Molecule

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathophygiological Investigations of ATRAP in Renal Tubules on Kidney InjuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Deficiency of the kidney tubular angiotensin II type1 receptor?associated protein ATRAP exacerbates streptozotocin-induced diabetic glomerular injury via reducing protective macrophage polarization2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of effects of SGLT-2 inhibitors and GLP-1 receptor agonists on cardiovascular and renal outcomes in type 2 diabetes mellitus patients with/without albuminuria: A systematic review and network meta-analysis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Systematic review and meta-analysis for prevention of cardiovascular complications using GLP-1 receptor agonists and SGLT-2 inhibitors in obese diabetic patients2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prevention of kidney function decline using uric acid-lowering therapy in chronic kidney disease patients: a systematic review and network meta-analysis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aristolochic Acid Induces Renal Fibrosis and Senescence in Mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of Rikkunshito treatment on renal fibrosis/inflammation and body weight reduction in a unilateral ureteral obstruction model in mice2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Angiotensin II type 1 receptor-associated protein deficiency attenuates sirtuin1 expression in an immortalised human renal proximal tubule cell line2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of ATRAP in Renal Proximal Tubules on Angiotensin‐Dependent Hypertension2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of rikkunshito on renal fibrosis and inflammation in angiotensin II-infused mice2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Angiotensin receptor-binding molecule in leukocytes in association with the systemic and leukocyte inflammatory profile2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Angiotensin II Type 1 Receptor-associated Protein Inhibits Angiotensin II-induced Insulin Resistance with Suppression of Oxidative Stress in Skeletal Muscle Tissue2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Early Enhanced Leucine-Rich α-2-Glycoprotein-1 Expression in Glomerular Endothelial Cells of Type 2 Diabetic Nephropathy Model Mice2018

Author(s)

Journal Title

Uneda Kazushi 畝田一司