Akimoto Naohiko 秋元直彦

… Alternative Names

秋元直彦アキモトナオヒコ

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Researcher Number	90787483
Other IDs
Affiliation (Current)	2025: 日本医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2025: 日本医科大学, 医学部, 助教 2022 – 2023: 日本医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 若年発症 / 早期発症大腸癌 / バイオバンク / 疾患感受性遺伝子座 / 一塩基変異多型 / early-onset / 大腸内視鏡 / スクリーニング / マクロファージ / T細胞 / 抗免疫腫瘍応答 / 早期発症大腸腺腫

大規模コホートによる早期発症大腸癌関連遺伝子座同定と臨床病理学的特徴との相関Principal Investigator
- Principal Investigator
  
  秋元直彦
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Nippon Medical School
抗腫瘍免疫応答による早期発症大腸癌・腺腫のリスクの層別化Principal Investigator
- Principal Investigator
  
  秋元直彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Nippon Medical School

All 2024 2023 2022

All Journal Article Presentation

[Journal Article] Potential of Direct Oral Anticoagulant in Bleeding After Gastric Endoscopic Submucosal Dissection: A Systematic Review and Meta-Analysis2024
- Author(s)
  Higuchi Kazutoshi、Goto Osamu、Matsuda Akihisa、Nakagome Shun、Habu Tsugumi、Ishikawa Yumiko、Koizumi Eriko、Kirita Kumiko、Noda Hiroto、Onda Takeshi、Akimoto Teppei、Omori Jun、Akimoto Naohiko、Yoshida Hiroshi、Iwakiri Katsuhiko
- Journal Title
  
  Digestive Diseases and Sciences
  
  Volume: 69 Issue: 3 Pages: 940-948
- DOI
  10.1007/s10620-024-08271-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15980
[Journal Article] Tumor size discrepancy between endoscopic and pathological evaluations in colorectal endoscopic submucosal dissection2024
- Author(s)
  Onda T, Goto O, Otsuka T, Hayasaka Y, Nakagome S, Habu T, Ishikawa Y, Kirita K, Koizumi E, Noda H, Higuchi K, Omori J, Akimoto N, Iwakiri K.
- Journal Title
  
  World J Gastrointest Endosc
  
  Volume: 16 Issue: 3 Pages: 136-147
- DOI
  10.4253/wjge.v16.i3.136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15980
[Journal Article] Treatment Decision for Locally Resected T1 Colorectal Carcinoma-Verification of the Japanese Guideline Criteria for Additional Surgery Based on Long-Term Clinical Outcomes2024
- Author(s)
  Oka S, Tanaka S, Kajiwara Y, Saito S, Fukunaga Y, Takamatsu M, ..., Akimoto N, Kobayashi H, Sugihara K, Ueno H.
- Journal Title
  
  American Journal of Gastroenterology
  
  Volume: 119 Issue: 10 Pages: 2019
- DOI
  10.14309/ajg.0000000000002715
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15980
[Journal Article] Enrichment of Bacteroides fragilis and enterotoxigenic Bacteroides fragilis in CpG island methylator phenotype-high colorectal carcinoma2024
- Author(s)
  Takashima Yasutoshi、Kawamura Hidetaka、Okadome Kazuo、Ugai Satoko、Haruki Koichiro、Arima Kota、Mima Kosuke、Akimoto Naohiko、Nowak Jonathan A.、Giannakis Marios、Garrett Wendy S.、Sears Cynthia L.、Song Mingyang、Ugai Tomotaka、Ogino Shuji
- Journal Title
  
  Clinical Microbiology and Infection
  
  Volume: 30 Issue: 5 Pages: 630-636
- DOI
  10.1016/j.cmi.2024.01.013
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15980, KAKENHI-PROJECT-23K15435, KAKENHI-PROJECT-21K08686, KAKENHI-PROJECT-21K08805
[Journal Article] Inverse relationship between Fusobacterium nucleatum amount and tumor CD274 (PD‐L1) expression in colorectal carcinoma2023
- Author(s)
  Ugai T, Shimizu T, Kawamura H, Ugai S, Takashima Y, Usui G, Vayrynen JP, Okadome K, Haruki K, Akimoto N, Masugi Y, da Silva A, Mima K, Zhang X, Chan AT, Wang M, Garrett WS, Freeman GJ, Meyerhardt JA, Nowak JA, Song M, Giannakis M, Ogino S
- Journal Title
  
  Clinical & Translational Immunology
  
  Volume: 12 Issue: 8 Pages: 1453-1453
- DOI
  10.1002/cti2.1453
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15980, KAKENHI-PROJECT-23K15435, KAKENHI-PROJECT-21K08805, KAKENHI-PROJECT-20K17210
[Journal Article] A successful treatment case of refractory hemorrhagic ulcer with eosinophilic gastritis by endoscopic hand suturing2023
- Author(s)
  Nakagome Shun、Koizumi Eriko、Goto Osamu、Kitamura Michika、Kawami Noriyuki、Higuchi Kazutoshi、Onda Takeshi、Omori Jun、Akimoto Naohiko、Iwakiri Katsuhiko
- Journal Title
  
  DEN Open
  
  Volume: 3 Issue: 1
- DOI
  10.1002/deo2.207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15980
[Journal Article] Chronological Changes in Mucosal Deformity by Endoscopic Suturing after Gastric Endoscopic Submucosal Dissection: A Multicenter Retrospective Analysis2023
- Author(s)
  Higuchi Kazutoshi、Goto Osamu、Takahashi Akiko、Akimoto Teppei、Habu Tsugumi、Ishikawa Yumiko、Kirita Kumiko、Koizumi Eriko、Noda Hiroto、Onda Takeshi、Omori Jun、Akimoto Naohiko、Kaise Mitsuru、Yahagi Naohisa、Oyama Tsuneo、Iwakiri Katsuhiko
- Journal Title
  
  Digestion
  
  Volume: 104 Issue: 2 Pages: 121-128
- DOI
  10.1159/000527350
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15980
[Journal Article] White Blood Cell Counts and Future Relapse in Ulcerative Colitis under Low-Dose Thiopurine Treatment in Real-World Practice: A 3-Year Japanese Multi-Center Retrospective Cohort Study2023
- Author(s)
  Kiyohara H, Yamazaki H, Moriya K, Akimoto N, Kawai S, Takenaka K, Fukuda T, Tominaga K, Umeno J, Shinzaki S, Honzawa Y, Takagi T, Ichikawa H, Endo T, Ozaki R, Andoh A, Matsuoka K, Hibi T, Kobayashi T
- Journal Title
  
  Inflammatory Intestinal Diseases
  
  Volume: 9 Issue: 1 Pages: 1-10
- DOI
  10.1159/000535889
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15980, KAKENHI-PROJECT-22K08055, KAKENHI-PROJECT-23K07426
[Journal Article] Prognostic role of detailed colorectal location and tumor molecular features: analyses of 13,101 colorectal cancer patients including 2994 early-onset cases2023
- Author(s)
  Ugai T, Akimoto N, Haruki K, Harrison TA, Cao Y, Qu C, Chan AT, Campbell PT, ..., Song M, Nowak JA, Peters U, Phipps AI, Ogino S.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 58 Issue: 3 Pages: 229-245
- DOI
  10.1007/s00535-023-01955-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15980, KAKENHI-PROJECT-21K08805
[Journal Article] Comparison of Linked Color Imaging and White Light Imaging Colonoscopy for Detection of Colorectal Adenoma Requiring Endoscopic Treatment: A Single-Center Randomized Controlled Trial2023
- Author(s)
  Tanaka Shu、Omori Jun、Hoshimoto Aitoshi、Nishimoto Takayoshi、Akimoto Naohiko、Tatsuguchi Atsushi、Fujimori Shunji、Iwakiri Katsuhiko
- Journal Title
  
  Journal of Nippon Medical School
  
  Volume: 90 Issue: 1 Pages: 111-120
- DOI
  10.1272/jnms.JNMS.2023_90-117
- ISSN
  1345-4676, 1347-3409
- Year and Date
  2023-02-25
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15980
[Journal Article] Clinical significance of programmed cell death-ligand expression in small bowel adenocarcinoma is determined by the tumor microenvironment2023
- Author(s)
  Hoshimoto Aitoshi、Tatsuguchi Atsushi、Hamakubo Ryohei、Nishimoto Takayoshi、Omori Jun、Akimoto Naohiko、Tanaka Shu、Fujimori Shunji、Hatori Tsutomu、Shimizu Akira、Iwakiri Katsuhiko
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 29 Issue: 40 Pages: 5566-5581
- DOI
  10.3748/wjg.v29.i40.5566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15980
[Journal Article] How Does Omitting Additional Surgery after Local Excision Affect the Prognostic Outcome of Patients with High-risk T1 Colorectal Cancer?2023
- Author(s)
  Ouchi A, Komori K, Masahiro T, Toriyama K, Kajiwara Y, Oka S, ..., Akimoto N, Kobayashi H, Ajioka Y, Sugihara K, Ueno H
- Journal Title
  
  Annals of Surgery
  
  Volume: 279 Issue: 2 Pages: 290
- DOI
  10.1097/sla.0000000000006092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15980
[Journal Article] Nomogram as a novel predictive tool for lymph node metastasis in T1 colorectal cancer treated with endoscopic resection: a nationwide, multicenter study2023
- Author(s)
  Kajiwara Yoshiki、Oka Shiro、Tanaka Shinji、Nakamura Takahiro、Saito Shoichi、Fukunaga Yosuke、Takamatsu Manabu、Kawachi Hiroshi、Hotta Kinichi、Ikematsu Hiroaki、Kojima Motohiro、Saito Yutaka、Yamada Masayoshi、Kanemitsu Yukihide、Sugai Tamotsu、etc
- Journal Title
  
  Gastrointestinal Endoscopy
  
  Volume: 97 Issue: 6 Pages: 1119-1128
- DOI
  10.1016/j.gie.2023.01.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07412, KAKENHI-PROJECT-22K15980, KAKENHI-PROJECT-23K27678
[Journal Article] Relationship Between Immunophenotypes, Genetic Profiles, and Clinicopathologic Characteristics in Small Bowel Adenocarcinoma2023
- Author(s)
  Hoshimoto Aitoshi、Tatsuguchi Atsushi、Yamada Takeshi、Kuriyama Sho、Hamakubo Ryohei、Nishimoto Takayoshi、Omori Jun、Akimoto Naohiko、Gudis Katya、Mitsui Keigo、Tanaka Shu、Fujimori Shunji、Hatori Tsutomu、Shimizu Akira、Iwakiri Katsuhiko
- Journal Title
  
  American Journal of Surgical Pathology
  
  Volume: 48 Issue: 2 Pages: 127-139
- DOI
  10.1097/pas.0000000000002161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15980
[Journal Article] Prophylactic use of steroids for a mucosal defect with a circumference of less than three-fourths prevents both symptomatic and asymptomatic stricture after esophageal endoscopic submucosal dissection2023
- Author(s)
  Koizumi Eriko、Habu Tsugumi、Goto Osamu、Nakagome Shun、Ishikawa Yumiko、Kirita Kumiko、Noda Hiroto、Higuchi Kazutoshi、Onda Takeshi、Akimoto Teppei、Omori Jun、Akimoto Naohiko、Iwakiri Katsuhiko
- Journal Title
  
  Surgical Endoscopy
  
  Volume: 37 Issue: 8 Pages: 5875-5882
- DOI
  10.1007/s00464-023-09988-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15980
[Journal Article] Technical outcomes and postprocedural courses of mucosal incision‐assisted biopsy for possible gastric gastrointestinal stromal tumors: A series of 48 cases (with video)2023
- Author(s)
  Koizumi Eriko、Goto Osamu、Nakagome Shun、Habu Tsugumi、Ishikawa Yumiko、Kirita Kumiko、Noda Hiroto、Higuchi Kazutoshi、Onda Takeshi、Akimoto Teppei、Omori Jun、Akimoto Naohiko、Iwakiri Katsuhiko
- Journal Title
  
  DEN Open
  
  Volume: 4 Issue: 1
- DOI
  10.1002/deo2.264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15980
[Journal Article] Molecular Characteristics of Early-Onset Colorectal Cancer According to Detailed Anatomical Locations: Comparison With Later-Onset Cases2023
- Author(s)
  Ugai T, Haruki K, Harrison TA, Cao Y, Qu C, Chan AT, Campbell PT, Akimoto N, ..., Song M, Nowak JA, Phipps AI, Peters U, Ogino S.
- Journal Title
  
  American Journal of Gastroenterology
  
  Volume: 118 Issue: 4 Pages: 712-726
- DOI
  10.14309/ajg.0000000000002171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15980, KAKENHI-PROJECT-21K08805
[Presentation] Validation of our new protocol for colonic diverticular hemorrhage for adjusting the timing of emergency endoscopic procedures.2023
- Author(s)
  Shimazu Y, Akimoto N, Omori J, Tatsuguchi A, Hoshimoto A, Nishimoto T, Goto O, Iwakiri K.
- Organizer
  UEG Week 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15980
[Presentation] Clinicopathological features of early-onset colorectal tumors diagnosed age at 40 or under.2023
- Author(s)
  Motomiya R, Akimoto N, Tatsuguchi A, Hoshimoto A, Nishimoto T, Omori J, Goto O, Ohashi R, Iwakiri K.
- Organizer
  UEG Week 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15980
[Presentation] 40歳未満で発症した若年者大腸腫瘍の臨床病理学的特徴2023
- Author(s)
  秋元直彦、辰口篤志、後藤修、石川裕美子、小泉英里子、星本相理、樋口和寿、西本崇良、大森順、大橋隆治、岩切勝彦
- Organizer
  第98回大腸癌研究会学術集会
- Data Source
  KAKENHI-PROJECT-22K15980
[Presentation] 大腸Ip型腺腫に対するcold snare polypectomyの是非2023
- Author(s)
  秋元直彦, 後藤修, 石川裕美子, 小泉英里子, 星本相理, 樋口和寿, 西本崇良, 大森順, 辰口篤志, 大橋隆治, 岩切勝彦
- Organizer
  第105回日本消化器内視鏡学会総会
- Data Source
  KAKENHI-PROJECT-22K15980
[Presentation] Endoscopic resection of a pedunculated type adenoma: pros and cons of cold snare polypectomy.2023
- Author(s)
  Akimoto N, Goto O, Ishikawa Y, Koizumi E, Hoshimoto A, Higuchi K, Nishimoto T, Omori J, Tatsuguchi A, Ohashi R, Iwakiri K.
- Organizer
  UEG Week 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15980
[Presentation] Cold snare polypectomyにおける側方断端不明因子の検討.2023
- Author(s)
  秋元直彦, 後藤修, 岩切勝彦
- Organizer
  第31回日本消化器関連学会週間（JDDW2023）
- Data Source
  KAKENHI-PROJECT-22K15980
[Presentation] 早期発症大腸腫瘍の臨床病理学的特徴2023
- Author(s)
  秋元直彦、辰口篤志、後藤修、中込峻、土生亜実、石川裕美子、濱窪亮平、小泉英里子、星本相理、桐田久美子、野田啓人、樋口和寿、恩田毅、西本崇良、飽本哲兵、大森順、田中周、藤森俊二、大橋隆治、岩切勝彦
- Organizer
  第19回日本消化管学会総会学術集会
- Data Source
  KAKENHI-PROJECT-22K15980
[Presentation] 50歳未満で発症した早期発症大腸腺腫の臨床病理学的特徴2022
- Author(s)
  秋元直彦、辰口篤志、後藤修、土生亜実、石川裕美子、濱窪亮平、小泉英里子、星本相理、桐田久美子、野田啓人、樋口和寿、恩田毅、西本崇良、飽本哲兵、大森順、田中周、藤森俊二、貝瀬満、岩切勝彦
- Organizer
  JDDW 2022
- Data Source
  KAKENHI-PROJECT-22K15980
[Presentation] 50歳未満で発症した早期発症大腸腫瘍ESD症例の臨床病理学的特徴2022
- Author(s)
  秋元直彦、後藤修、土生亜実、石川裕美子、小泉英里子、桐田久美子、野田啓人、樋口和寿、恩田毅、飽本哲兵、大森順、辰口篤志、岩切勝彦
- Organizer
  第103回日本消化器内視鏡学会総会
- Data Source
  KAKENHI-PROJECT-22K15980

1. 山田岳史 (50307948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 山口博樹 (90297937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 菅井有

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Akimoto Naohiko 秋元 直彦

秋元 直彦 アキモト ナオヒコ

Research Projects

Research Products

Co-Researchers

大規模コホートによる早期発症大腸癌関連遺伝子座同定と臨床病理学的特徴との相関Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

抗腫瘍免疫応答による早期発症大腸癌・腺腫のリスクの層別化Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Potential of Direct Oral Anticoagulant in Bleeding After Gastric Endoscopic Submucosal Dissection: A Systematic Review and Meta-Analysis2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tumor size discrepancy between endoscopic and pathological evaluations in colorectal endoscopic submucosal dissection2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Treatment Decision for Locally Resected T1 Colorectal Carcinoma-Verification of the Japanese Guideline Criteria for Additional Surgery Based on Long-Term Clinical Outcomes2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enrichment of Bacteroides fragilis and enterotoxigenic Bacteroides fragilis in CpG island methylator phenotype-high colorectal carcinoma2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inverse relationship between Fusobacterium nucleatum amount and tumor CD274 (PD‐L1) expression in colorectal carcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A successful treatment case of refractory hemorrhagic ulcer with eosinophilic gastritis by endoscopic hand suturing2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chronological Changes in Mucosal Deformity by Endoscopic Suturing after Gastric Endoscopic Submucosal Dissection: A Multicenter Retrospective Analysis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] White Blood Cell Counts and Future Relapse in Ulcerative Colitis under Low-Dose Thiopurine Treatment in Real-World Practice: A 3-Year Japanese Multi-Center Retrospective Cohort Study2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic role of detailed colorectal location and tumor molecular features: analyses of 13,101 colorectal cancer patients including 2994 early-onset cases2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of Linked Color Imaging and White Light Imaging Colonoscopy for Detection of Colorectal Adenoma Requiring Endoscopic Treatment: A Single-Center Randomized Controlled Trial2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Clinical significance of programmed cell death-ligand expression in small bowel adenocarcinoma is determined by the tumor microenvironment2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] How Does Omitting Additional Surgery after Local Excision Affect the Prognostic Outcome of Patients with High-risk T1 Colorectal Cancer?2023

Author(s)

Journal Title

DOI

Data Source

Akimoto Naohiko 秋元直彦

秋元直彦アキモトナオヒコ