Maki Shintaro 真木晋太郎

… Alternative Names

Shintaro Maki 真木晋太郎

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Researcher Number	90794371
Other IDs
Affiliation (Current)	2025: 三重大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2025: 三重大学, 医学部附属病院, 助教 2019 – 2023: 三重大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related
Keywords	Principal Investigator sFlt-1 / PlGF / タダラフィル / 胎児発育不全 / Angiogenic factor / 子宮動脈血流量 / angiogenic factor / FGR / 臍帯動脈PI / 超音波ドプラ / 胎児-胎盤循環 / 胎盤機能不全 / PDE5阻害薬 … More Except Principal Investigator … More 胎児発育不全 / PDE5阻害薬 / 新生児肺高血圧 / ホスホジエステラーゼ5阻害薬 / タダラフィル / 胎児低酸素性虚血性脳症 / 胎盤機能不全 / 神経損傷 / 胎児心拍モニタリング / 分娩監視 / 胎児心拍細変動 / 炎症 / 胎児子宮内感染 / 胎児心拍変動 / 自律神経 / 胎児生理学 / 胎児well being / 胎児心拍数モニタリング / 胎児心拍数変動 / 胎児発育遅延 Less

FGRに対するタダラフィル胎内治療を行った児の予後に関する研究Principal Investigator
- Principal Investigator
  
  真木晋太郎
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Mie University
胎児の脳損傷を予防するための心拍細変動解析による分娩監視指標の開発
- Principal Investigator
  
  真川祥一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Mie University
分娩時胎児酸素化能改善を目的とした母体へのタダラフィル投与の安全性についての検証
- Principal Investigator
  
  田中博明
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Mie University
胎児発育不全治療薬のタダラフィルが胎児新生児循環に与える影響の解析
- Principal Investigator
  
  池田智明
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Mie University
ホスホジエステラーゼ5阻害薬：タダラフィル投与による胎児発育改善のメカニズム解明Principal Investigator
- Principal Investigator
  
  真木晋太郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Mie University
Establishment of the molecular basis for the safety of tadalafil administration for fetal growth retardation.
- Principal Investigator
  
  Ikeda Tomoaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Mie University
Elucidation of pathological improvement mechanism by tadalafil administration in placental dysfunctionPrincipal Investigator
- Principal Investigator
  
  Shintaro Maki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Mie University

All 2024 2023 2021 2020 2019

All Journal Article Presentation

[Journal Article] Tadalafil for Treatment of Fetal Growth Restriction: A Review of Experimental and Clinical Studies2024
- Author(s)
  Maki Shintaro、Takakura Sho、Tsuji Makoto、Magawa Shoichi、Tamaishi Yuya、Nii Masafumi、Kaneda Michiko、Yoshida Kenta、Toriyabe Kuniaki、Kondo Eiji、Ikeda Tomoaki
- Journal Title
  
  Biomedicines
  
  Volume: 12 Issue: 4 Pages: 804-804
- DOI
  10.3390/biomedicines12040804
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15896
[Journal Article] Evaluation of fetal acidemia during delivery using the conventional 5-tier classification and Rainbow systems2024
- Author(s)
  Magawa S, Maki S, Nii M, Yamaguchi M, Tamaishi Y, Enomoto N, Takakura S, Toriyabe K, Kondo E, Ikeda T.
- Journal Title
  
  PLoS ONE
  
  Volume: 18 Issue: 6 Pages: e0287535-e0287535
- DOI
  10.1371/journal.pone.0287535
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09545
[Journal Article] Two-dimensional phase-contrast MRI reveals changes in uterine arterial blood flow in pregnant women administered tadalafil for fetal growth restriction2024
- Author(s)
  Nii Masafumi、Enomoto Naosuke、Ishida Masaki、Magawa Shoichi、Takakura Sho、Maki Shintaro、Tanaka Kayo、Toriyabe Kuniaki、Tanaka Hiroaki、Kondo Eiji、Sakuma Hajime、Ikeda Tomoaki
- Journal Title
  
  Placenta
  
  Volume: 146 Pages: 1-8
- DOI
  10.1016/j.placenta.2023.12.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15896, KAKENHI-PROJECT-22K16877
[Journal Article] sFlt-1 value predicts pregnancy prolongation periods from diagnosis in pregnant women diagnosed with early-onset preeclampsia2020
- Author(s)
  Hiroaki Tanaka , Yuko Nagahashi , Kuniaki Toriyabe , Shintaro Maki , Sho Takakura , Naosuke Enomoto , Kayo Tanaka , Katsuragi Shinji & Tomoaki Ikeda
- Journal Title
  
  The Journal of Maternal-Fetal & Neonatal Medicine
  
  Volume: online Issue: 21 Pages: 1-4
- DOI
  10.1080/14767058.2020.1849093
- Data Source
  KAKENHI-PROJECT-19K18694
[Journal Article] Tadalafil Treatment Ameliorates Hypoxia and Alters Placental Expression of Proteins Downstream of mTOR Signaling in Fetal Growth Restriction.2020
- Author(s)
  Tsuchiya K, Tanaka K, Tanaka H, Maki S, Enomoto N, Takakura S, Nii M, Toriyabe K, Katsuragi S, Ikeda T.
- Journal Title
  
  Medicina (Kaunas).
  
  Volume: 56(12) Issue: 12 Pages: 722-722
- DOI
  10.3390/medicina56120722
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17134, KAKENHI-PROJECT-19K18638, KAKENHI-PROJECT-19K18694
[Journal Article] Developmental Evaluation of Infants Who Have Received Tadalafil in Utero for Fetal Growth Restriction2020
- Author(s)
  Maki Shintaro、Kato Ineko、Enomoto Naosuke、Takakura Sho、Nii Masafumi、Tanaka Kayo、Tanaka Hiroaki、Hori Shinsuke、Matsuda Kana、Ueda Yukito、Sawada Hirofumi、Hirayama Masahiro、Sudo Akihiro、Ikeda Tomoaki
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 9 Issue: 5 Pages: 1448-1448
- DOI
  10.3390/jcm9051448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09800, KAKENHI-PROJECT-19K17134
[Journal Article] Safety Evaluation of Tadalafil Treatment for Fetuses with Early-Onset Growth Restriction (TADAFER): Results from the Phase II Trial2019
- Author(s)
  Maki Shintaro、Tanaka Hiroaki、Tsuji Makoto、Furuhashi Fumi、Magawa Shoichi、Kaneda Michiko K.、Nii Masafumi、Tanaka Kayo、Kondo Eiji、Tamaru Satoshi、Ogura Toru、Nishimura Yuki、Endoh Masayuki、Kimura Tadashi、Kotani Tomomi、Sekizawa Akihiko、Ikeda Tomoaki
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 8 Issue: 6 Pages: 856-856
- DOI
  10.3390/jcm8060856
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09800, KAKENHI-PROJECT-19K17134
[Journal Article] Tadalafil treatment in mice for preeclampsia with fetal growth restriction has neuro-benefic effects in offspring through modulating prenatal hypoxic conditions.2019
- Author(s)
  Tachibana Ryota, Umekawa Takashi, Yoshikawa Kento, Owa Takao, Magawa Shoichi, Furuhashi Fumi, Tsuji Makoto, Maki Shintaro, Shimada Kyoko, Kaneda K. Michiko, Nii Masafumi, Tanaka Hiroaki, Tanaka Kayo, Kamimoto Yuki, Kondo Eiji, Kato Ineko, Ikemura Kenji, Okuda Masahiro, et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 234-234
- DOI
  10.1038/s41598-018-36084-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08411, KAKENHI-PROJECT-17K08412, KAKENHI-PROJECT-17K09168, KAKENHI-PROJECT-17H04654, KAKENHI-PROJECT-19K08343, KAKENHI-PROJECT-19K09800, KAKENHI-PROJECT-19K17134, KAKENHI-PROJECT-17K16316
[Presentation] 正常妊娠における分娩時の胎児心拍変動挙動2023
- Author(s)
  真川祥一　真木晋太郎　玉石雄也　榎本尚助　高倉翔　二井理文　鳥谷部邦明　田中博明　近藤英司　池田智明
- Organizer
  母体胎児学会
- Data Source
  KAKENHI-PROJECT-22K09545
[Presentation] Tadalafil therapy for FGR; trajectory and prospects2023
- Author(s)
  真木晋太郎
- Organizer
  49th Annual Fetal and Neonatal Physiological Society Meeting 2023
- Data Source
  KAKENHI-PROJECT-22K15896
[Presentation] FGRに対する介入研究の歴史2023
- Author(s)
  真木晋太郎
- Organizer
  第59回日本周産期・新生児医学会
- Invited
- Data Source
  KAKENHI-PROJECT-22K15896
[Presentation] Fetal heart rate variability behavior during labor and delivery in normal pregnancy2023
- Author(s)
  Shoichi Magawa, Shintaro Maki, Tomoaki Ikeda
- Organizer
  49th Annual Fetal and Neonatal Physiological Society Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09545
[Presentation] タダラフィル経母体投与における新生児Rebound effectの評価2023
- Author(s)
  真木晋太郎
- Organizer
  第33回日本産婦人科・新生児血液学会学術集会
- Data Source
  KAKENHI-PROJECT-22K15896
[Presentation] sFlt-1・PlGF を用いた妊娠高血圧症候群における妊娠残存期間の予測2023
- Author(s)
  高倉翔、田中博明、玉石雄也、榎本尚助、真川祥一、真木晋太郎、二井理文、田中佳世、鳥谷部邦明、近藤英司、池田智明
- Organizer
  第 33 回日本産婦人科・新生児血液学会学術集会
- Data Source
  KAKENHI-PROJECT-22K15896
[Presentation] Placental insufficiencyに対するPDE5阻害薬（タダラフィル）の有用性2021
- Author(s)
  真木晋太郎
- Organizer
  第41回日本妊娠高血圧学会学術集会
- Data Source
  KAKENHI-PROJECT-19K18694
[Presentation] FGRに対するタダラフィルの経母体投与による胎児胎盤循環動態の変化に関する検討2021
- Author(s)
  真木晋太郎、田中博明、榎本尚助、高倉翔、二井理文、田中佳世、桂木真司、仲村将光、小谷友美、遠藤誠之、関沢明彦、木村正、池田智明
- Organizer
  第73回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K18694
[Presentation] FGRに対するタダラフィルの経母体投与による胎児胎盤循環動態の変化に関する検討2021
- Author(s)
  真木晋太郎、田中博明、榎本尚助、高倉翔、二井理文、田中佳世、桂木真司、仲村将光、小谷友美、遠藤誠之、関沢明彦、木村正、池田智明
- Organizer
  第73回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K18694
[Presentation] FGRに対するタダラフィルの投与による胎児胎盤循環評価　-TADAFER II試験における超音波ドプラ解析-2020
- Author(s)
  真木晋太郎、田中博明、高倉翔、辻誠、二井理文、田中佳世、桂木真司、小谷友美、遠藤誠之、関沢明彦、木村正、池田智明
- Organizer
  日本産婦人科・新生児血液学会　第30回学術集会
- Data Source
  KAKENHI-PROJECT-19K18694
[Presentation] FGRに対するタダラフィルの投与による胎児胎盤循環評価　 TADAFERⅡ試験における超音波ドプラ解析2020
- Author(s)
  真木晋太郎、田中博明、高倉翔、辻誠、二井理文、田中佳世、桂木真司、小谷友美、遠藤誠之、関沢明彦、木村正、池田智明
- Organizer
  第30回日本産婦人科・新生児血液学会　学術集会
- Data Source
  KAKENHI-PROJECT-19K18694

1. Ikeda Tomoaki (80202894)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
2. 田中博明 (30727996)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. 田中佳世 (60812310)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. 真川祥一 (40812300)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. 二井理文 (90790832)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. 松田直 (50361100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 高倉翔 (70868372)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. IKEMURA Kenji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 奥田真弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Maki Shintaro 真木 晋太郎

Shintaro Maki 真木 晋太郎

Research Projects

Research Products

Co-Researchers

FGRに対するタダラフィル胎内治療を行った児の予後に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

胎児の脳損傷を予防するための心拍細変動解析による分娩監視指標の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

分娩時胎児酸素化能改善を目的とした母体へのタダラフィル投与の安全性についての検証

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

胎児発育不全治療薬のタダラフィルが胎児新生児循環に与える影響の解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ホスホジエステラーゼ5阻害薬：タダラフィル投与による胎児発育改善のメカニズム解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of the molecular basis for the safety of tadalafil administration for fetal growth retardation.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of pathological improvement mechanism by tadalafil administration in placental dysfunctionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Tadalafil for Treatment of Fetal Growth Restriction: A Review of Experimental and Clinical Studies2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of fetal acidemia during delivery using the conventional 5-tier classification and Rainbow systems2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Two-dimensional phase-contrast MRI reveals changes in uterine arterial blood flow in pregnant women administered tadalafil for fetal growth restriction2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] sFlt-1 value predicts pregnancy prolongation periods from diagnosis in pregnant women diagnosed with early-onset preeclampsia2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tadalafil Treatment Ameliorates Hypoxia and Alters Placental Expression of Proteins Downstream of mTOR Signaling in Fetal Growth Restriction.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Developmental Evaluation of Infants Who Have Received Tadalafil in Utero for Fetal Growth Restriction2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Safety Evaluation of Tadalafil Treatment for Fetuses with Early-Onset Growth Restriction (TADAFER): Results from the Phase II Trial2019

Author(s)

Journal Title

Maki Shintaro 真木晋太郎

Shintaro Maki 真木晋太郎

[Presentation] sFlt-1・PlGF を用いた妊娠高血圧症候群における妊娠残存期間の予測2023

[Presentation] FGRに対するタダラフィルの経母体投与による胎児胎盤循環動態の変化に関する検討2021

[Presentation] FGRに対するタダラフィルの投与による胎児胎盤循環評価　-TADAFER II試験における超音波ドプラ解析-2020

[Presentation] FGRに対するタダラフィルの投与による胎児胎盤循環評価　 TADAFERⅡ試験における超音波ドプラ解析2020