Kawagishi Takahiro 川岸崇裕

Researcher Number	90800029
Other IDs
Affiliation (Current)	2026: 大阪大学, 微生物病研究所, 助教
Affiliation (based on the past Project Information) *help	2024 – 2025: 大阪大学, 先端モダリティ・ドラッグデリバリーシステム研究センター, 特任助教(常勤) 2018 – 2019: 大阪大学, 微生物病研究所, 特任研究員(常勤) 2017: 大阪大学, 微生物病研究所, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 49060:Virology-related / 0803:Pathology, infection/immunology, and related fields Except Principal Investigator Virology
Keywords	Principal Investigator ロタウイルス / リバースジェネティクス / 経口投与型ワクチン / ウイルスベクター / 腸管免疫 / 遺伝子操作技術 / 感染受容体 / ウイルス感染 / 腸管感染性ウイルス / 受容体 … More / 新興感染症 / 遺伝子操作系 / 細胞侵入 / コウモリ / レオウイルス … More Except Principal Investigator 治療 / 腫瘍溶解ウイルス / 癌治療 / 腫瘍溶解性ウイルス / 遺伝子治療 / 癌 / レオウイルス Less

遺伝子操作系を用いたヒト腸管細胞におけるヒトロタウイルスの侵入機構の解析Principal Investigator
- Principal Investigator
  
  川岸崇裕
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  The University of Osaka
ロタウイルスを用いた新規の腸管指向性ウイルスベクター型ワクチンの開発Principal Investigator
- Principal Investigator
  
  川岸崇裕
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0803:Pathology, infection/immunology, and related fields
- Research Institution
  Osaka University
Molecular mechanisms of viral infection by Nelson Bay Reovirus isolated from humansPrincipal Investigator
- Principal Investigator
  
  Kawagishi Takahiro
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Osaka University
Development of viral oncolytic agent using mammalian orthoreovirus with improved infectivity
- Principal Investigator
  
  KANAI YUTA
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  Osaka University

All 2025 2024 2020 2019 2018 2016

All Journal Article Presentation

[Journal Article] Innate immune sensing of rotavirus by intestinal epithelial cells leads to diarrhea2025
- Author(s)
  Hou Gaopeng、Son Juhee、Gomez Castro Maria Florencia、Kawagishi Takahiro、Ren Xingxing、Roth Alexa N.、Antia Avan、Zeng Qiru、DeVeaux Anna L.、Feng Ningguo、Kohio Hinissan P.、Baldridge Megan T.、Dermody Terence S.、Zhu Shu、Ding Siyuan
- Journal Title
  
  Cell Host & Microbe
  
  Volume: 33 Issue: 3 Pages: 408-419.e8
- DOI
  10.1016/j.chom.2025.02.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K23314
[Journal Article] Viroporin activity is necessary for intercellular calcium signals that contribute to viral pathogenesis2025
- Author(s)
  Gebert J. Thomas、Scribano Francesca J.、Engevik Kristen A.、Huleatt Ethan M.、Eledge Michael R.、Dorn Lauren E.、Philip Asha A.、Kawagishi Takahiro、Greenberg Harry B.、Patton John T.、Hyser Joseph M.
- Journal Title
  
  Science Advances
  
  Volume: 11 Issue: 3
- DOI
  10.1126/sciadv.adq8115
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K23314
[Journal Article] Rhesus rotavirus NSP1 mediates extra-intestinal infection and is a contributing factor for biliary obstruction2024
- Author(s)
  Li Enkai、Feng Ningguo、Zeng Qiru、Sanchez-Tacuba Liliana、Kawagishi Takahiro、Branham Grace、Hou Gaopeng、Wang Zemin、Greenberg Harry B.、Ding Siyuan
- Journal Title
  
  PLOS Pathogens
  
  Volume: 20 Issue: 9 Pages: e1012609-e1012609
- DOI
  10.1371/journal.ppat.1012609
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K23314
[Journal Article] Chimeric Viruses Enable Study of Antibody Responses to Human Rotaviruses in Mice2024
- Author(s)
  Woodyear Sarah、Chandler Tawny L.、Kawagishi Takahiro、Lonergan Tom M.、Patel Vanshika A.、Williams Caitlin A.、Permar Sallie R.、Ding Siyuan、Caddy Sarah L.
- Journal Title
  
  Viruses
  
  Volume: 16 Issue: 7 Pages: 1145-1145
- DOI
  10.3390/v16071145
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K23314
[Journal Article] Reverse Genetics of Murine Rotavirus: A Comparative Analysis of the Wild-Type and Cell-Culture-Adapted Murine Rotavirus VP4 in Replication and Virulence in Neonatal Mice2024
- Author(s)
  Kawagishi Takahiro、Sanchez-Tacuba Liliana、Feng Ningguo、Greenberg Harry B.、Ding Siyuan
- Journal Title
  
  Viruses
  
  Volume: 16 Issue: 5 Pages: 767-767
- DOI
  10.3390/v16050767
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K23314
[Journal Article] CRISPR/Cas9 screens identify key host factors that enhance rotavirus reverse genetics efficacy and vaccine production2024
- Author(s)
  Zhu Yinxing、Sullender Meagan E.、Campbell Danielle E.、Wang Leran、Lee Sanghyun、Kawagishi Takahiro、Hou Gaopeng、Dizdarevic Alen、Jais Philippe H.、Baldridge Megan T.、Ding Siyuan
- Journal Title
  
  npj Vaccines
  
  Volume: 9 Issue: 1
- DOI
  10.1038/s41541-024-01007-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K23314
[Journal Article] Reverse Genetics System for a Human Group A Rotavirus.2020
- Author(s)
  Kawagishi T, Nurdin J, Onishi M, Nouda R, Kanai Y, Tajima T, Ushijima H, Kobayashi T
- Journal Title
  
  J Virol
  
  Volume: 94 Issue: 2
- DOI
  10.1128/jvi.00963-19
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-19H04835, KAKENHI-PROJECT-16H05360, KAKENHI-PROJECT-18H02663, KAKENHI-PROJECT-19J21852, KAKENHI-PROJECT-18K15167, KAKENHI-PROJECT-18K19444
[Journal Article] Development of Stable Rotavirus Reporter Expression Systems2019
- Author(s)
  Kanai Y, Kawagishi T, Nouda R, Onishi M, Pannacha P, Nurdin JA, Nomura K, Matsuura Y, Kobayashi T.
- Journal Title
  
  Journal of Virology
  
  Volume: 93 Issue: 4
- DOI
  10.1128/jvi.01774-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07145, KAKENHI-PROJECT-18K15167, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-17H05814, KAKENHI-PROJECT-18H02663, KAKENHI-PROJECT-18K19444
[Journal Article] Cell-cell fusion induced by reovirus FAST proteins enhances replication and pathogenicity of non-enveloped dsRNA viruses2019
- Author(s)
  2.Yuta Kanai, Takahiro Kawagishi, Yusuke Sakai, Ryotaro Nouda, Masayuki Shimojima, Masayuki Saijo, Yoshiharu Matsuura, Takeshi Kobayashi
- Journal Title
  
  PLoS Pathogens
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15167
[Journal Article] In Vivo Live Imaging of Oncolytic Mammalian Orthoreovirus Expressing NanoLuc Luciferase in Tumor Xenograft Mice2019
- Author(s)
  Kanai Yuta、Kawagishi Takahiro、Matsuura Yoshiharu、Kobayashi Takeshi
- Journal Title
  
  Journal of Virology
  
  Volume: 93 Issue: 14
- DOI
  10.1128/jvi.00401-19
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-19H04835, KAKENHI-PROJECT-18H02663, KAKENHI-PROJECT-18K15167, KAKENHI-PROJECT-18K19444
[Presentation] マウスロタウイルスにおけるリバースジェネティクスの確立と外来抗原を発現する組換えウイルスの作製 Establishment of reverse genetics for murine RV and its application to generate a recombinant murine RV expressing exogenous protein2024
- Author(s)
  川岸崇裕、松村香名子、小林剛、Harry Greenberg、Siyuan Ding
- Organizer
  第71回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-24K23314
[Presentation] Attenuation of simian rotavirus by multi-segment codon-pair deoptimization.2024
- Author(s)
  Zelin Chen, Tomohiro Kotaki, Takahiro Kawagishi, Katsuhisa Hirai, Shohei Minami, Yuta Kanai, Takeshi Kobayashi
- Organizer
  第71回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-24K23314
[Presentation] 株間ゲノム比較によるネルソンベイオルソレオウイルスの新規病原性因子の同定 Identifi cation of novel virulence factors of nelson bay orthoreovirus by genetic comparison between wild-type strains2024
- Author(s)
  播磨勇人, 佐々木道仁有泉拓馬, 川口虹穂, 小林広子, Intaruck Kittiya, 小林剛, 川岸崇裕, 金井祐太, 直亨則, 邱永晋, 梶原将大, 大場靖子, 伊藤直人, 石原加奈子, Bernard M Hangombe, 澤洋文
- Organizer
  第71回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-24K23314
[Presentation] Development of rotavirus vector as vaccine platform for intestinal pathogens2019
- Author(s)
  Yuta Kanai, Takahiro Kawagishi, Pimfhun Pannacha, Ryotaro Nouda, Misa Onishi, Jeffery A. Nurdin, Keiichiro Nomura, Lusiany Tina, Moeko Yamasaki, Takeshi Kobayashi
- Organizer
  The 67th Annual Meeting of Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-18K15167
[Presentation] Altered replication of recombinant rotaviruses expressing NSP3 lacking eIF4G binding domain2019
- Author(s)
  Ryotaro Nouda, Yuta Kanai, Takahiro Kawagishi, Pimfhun Pannacha, Takeshi Kobayashi
- Organizer
  The 67th Annual Meeting of Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-18K15167
[Presentation] Examination of rotavirus antigenemia and antigenuria by immunochromatography method and enzyme immunoassay2019
- Author(s)
  Hiroshi Ushijima, Itoe Shiota, Yuko Shimizu, Hidemasa Miyashita, Masaaki Kobayashi, Pattara Khamrin, Ariful Hoque, Sayaka Takanashi, Shoko Okitsu, Takahiro Kawagishi, Yuta Kanai, Satoshi Komoto, Koki Taniguchi, Takeshi Kobayashi, Takeshi Tajima, Niwat Maneekarn, Satoshi Hayakawa
- Organizer
  The 67th Annual Meeting of Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-18K15167
[Presentation] Development of stable reporter rotaviruses2018
- Author(s)
  Pannacha Pimfhun, Yuta Kanai, Misa Onishi, Takahiro Kawagishi, Ryotaro Nouda, Jeffery Nurdin, Yoshiharu Matsuura, Takeshi Kobayashi
- Organizer
  The 66th Annual Meeting of Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-18K15167
[Presentation] Nelson Bay Orthoreovirus σC body domain is associated with strain-specific differences in viral replication2018
- Author(s)
  Takahiro Kawagishi, Yuta Kanai, Yusuke Sakai, Ryotaro Nouda, Hideki Tani, Masayuki Shimojima, Masayuki Saijo, Yoshiharu Matsuura, Takeshi Kobayashi
- Organizer
  The 66th Annual Meeting of Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-18K15167
[Presentation] Antigenecity of simian and human reassortant rotaviruses generated by reverse genetics2018
- Author(s)
  Yuta Kanai, Takahiro Kawagishi, Misa Onishi, Pimfhun Pannacha, Ryotaro Nouda, Jeffery A. Nurdin, Keiichiro Nomura, Hiroshi Ushijima, Takeshi Kobayashi
- Organizer
  13th International dsRNA Virus Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15167
[Presentation] Nelson Bay Orthoreovirus σC determines strain-specific differences in viral replication and pathogenesis2018
- Author(s)
  Takahiro Kawagishi, Yuta Kanai, Yusuke Sakai, Ryotaro Nouda, Hideki Tani, Masayuki Shimojima, Masayuki Saijo, Yoshiharu Matsuura, Takeshi Kobayashi
- Organizer
  13th International dsRNA Virus Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15167
[Presentation] Platform for rotavirus vaccine development using plasmid-based reverse genetics2018
- Author(s)
  Yuta Kanai, Takahiro Kawagishi, Misa Onishi, Pimfhun Pannacha, Ryotaro Nouda, Jeffery A. Nurdin, Keiichiro Nomura, Hiroshi Ushijima, Takeshi Kobayashi
- Organizer
  The 66th Annual Meeting of Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-18K15167
[Presentation] Fusogenic bat-borne orthoreovirus p17 protein regulates viral replication in a host-specific manner2018
- Author(s)
  Ryotaro Nouda, Takahiro Kawagishi, Yuta Kanai, Masayuki Shimojima, Masayuki Saijo, Yoshiharu Matsuura, Takeshi Kobayashi
- Organizer
  The 66th Annual Meeting of Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-18K15167
[Presentation] In vivo live imaging of tumor by gene-modified mammalian orthoreovirus with exogenous luciferase transgene2016
- Author(s)
  金井祐太、川岸崇裕、松浦善治、小林剛
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌市・札幌コンベンションセンター
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-16K19138
[Presentation] レポーター遺伝子発現哺乳類オルソレオウイルスによる腫瘍の生体イメージング2016
- Author(s)
  金井祐太、川岸崇裕、松浦善治、小林剛
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  藤沢市・日本大学生物資源科学部（湘南キャンパス）
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-16K19138

1. KANAI YUTA (80506501)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. Kobayashi Takeshi (90324847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. Matsuura Yoshiharu (50157252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

Kawagishi Takahiro 川岸 崇裕

Research Projects

Research Products

Co-Researchers

遺伝子操作系を用いたヒト腸管細胞におけるヒトロタウイルスの侵入機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ロタウイルスを用いた新規の腸管指向性ウイルスベクター型ワクチンの開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of viral infection by Nelson Bay Reovirus isolated from humansPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of viral oncolytic agent using mammalian orthoreovirus with improved infectivity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Innate immune sensing of rotavirus by intestinal epithelial cells leads to diarrhea2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Viroporin activity is necessary for intercellular calcium signals that contribute to viral pathogenesis2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rhesus rotavirus NSP1 mediates extra-intestinal infection and is a contributing factor for biliary obstruction2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chimeric Viruses Enable Study of Antibody Responses to Human Rotaviruses in Mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reverse Genetics of Murine Rotavirus: A Comparative Analysis of the Wild-Type and Cell-Culture-Adapted Murine Rotavirus VP4 in Replication and Virulence in Neonatal Mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CRISPR/Cas9 screens identify key host factors that enhance rotavirus reverse genetics efficacy and vaccine production2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reverse Genetics System for a Human Group A Rotavirus.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of Stable Rotavirus Reporter Expression Systems2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cell-cell fusion induced by reovirus FAST proteins enhances replication and pathogenicity of non-enveloped dsRNA viruses2019

Author(s)

Journal Title

Data Source

[Journal Article] In Vivo Live Imaging of Oncolytic Mammalian Orthoreovirus Expressing NanoLuc Luciferase in Tumor Xenograft Mice2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] マウスロタウイルスにおけるリバースジェネティクスの確立と外来抗原を発現する組換えウイル スの作製 Establishment of reverse genetics for murine RV and its application to generate a recombinant murine RV expressing exogenous protein2024

Author(s)

Organizer

Kawagishi Takahiro 川岸崇裕

[Presentation] マウスロタウイルスにおけるリバースジェネティクスの確立と外来抗原を発現する組換えウイルスの作製 Establishment of reverse genetics for murine RV and its application to generate a recombinant murine RV expressing exogenous protein2024