Shigemori Suguru 重盛駿

Researcher Number	90803487
Affiliation (based on the past Project Information) *help	2019 – 2023: 信州大学, 先鋭領域融合研究群バイオメディカル研究所, 助教(特定雇用) 2018: 信州大学, 農学部, アソシエイト研究員 2017: 筑波大学, 医学医療系, 助教
Review Section/Research Field	Principal Investigator Basic Section 42010:Animal production science-related / Integrative animal science Except Principal Investigator Basic Section 42010:Animal production science-related / Studies on the Super-Aging Society / Animal production science / Medium-sized Section 50:Oncology and related fields
Keywords	Principal Investigator 腸内生態系 / 家畜用生菌剤 / ゆらぎモデルマウス / 腸内細菌 / マウス / 乳酸菌 / 生菌剤 / メタボロミクス / メタゲノミクス / 16Sメタゲノム解析 / 遺伝子改変マウス / 腸内細菌叢 … More Except Principal Investigator … More 乳酸菌 / 腸管 / 免疫 / 経口 / 微粒子 / オリゴDNA / 肺静脈心筋細胞 / 腸肺相関 / 腸管上皮 / スマート / スマート乳酸菌 / プロバイオティクス / 遺伝子組換え / リボソーム工学 / 育種 / 機能強化 / ナノカプセル / 腸管粘膜 / 乳酸菌DNA微粒子 / DNA微粒子 / 経口投与 / 腸内細菌 / 喘息モデル / 肺 / 乳酸菌オリゴDNA / 免疫調節 / 肺癌 / 経気道的標的治療 / 生物資源医薬 / 経気道治療 / 免疫チェックポイント阻害 / 肺がん / 遺伝子組換え乳酸菌 Less

腸内菌叢数値化法を基盤とした健全な腸内環境を安定化する乳酸菌生菌剤の創製Principal Investigator
- Principal Investigator
  
  重盛駿
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Shinshu University
Development of smart lactic acid bacteria
- Principal Investigator
  
  Shimosato Takeshi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Studies on the Super-Aging Society
- Research Institution
  Shinshu University
The Optimization of Oral Lactobacillus Oligodeoxynucleotide Microparticles and the Elucidation of Immune Regulation Mechanisms via Intestinal Epithelium
- Principal Investigator
  
  Shimosato Takeshi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Shinshu University
Innovative therapy for lung cancer: prophylaxis and therapy by intratracheal delivery of probiotics harboring immune checkpoint-blocking single-chain variable fragment
- Principal Investigator
  
  Sato Takashi
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Shinshu University
A quantitative comparison study of gut ecological change caused by host gene mutationsPrincipal Investigator
- Principal Investigator
  
  Shigemori Suguru
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Integrative animal science
- Research Institution
  Shinshu University
  University of Tsukuba
Study on the immune mechanism using oral nanocapsule with oligodeoxynucleotides from lactic acid bacteria
- Principal Investigator
  
  Shimosato Takeshi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Animal production science
- Research Institution
  Shinshu University

All 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Free feeding of CpG-oligodeoxynucleotide particles prophylactically attenuates allergic airway inflammation and hyperresponsiveness in mice2021
- Author(s)
  Okajima, T., Shigemori, S., Namai, F., Ogita, T., Sato, T. & Shimosato, T.
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 738041-738041
- DOI
  10.3389/fimmu.2021.738041
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03125, KAKENHI-PROJECT-19KK0208
[Journal Article] Oral administration of Flavonifractor plautii, a bacteria increased with green tea consumption, promotes recovery from acute colitis in mice via suppression of IL-172021
- Author(s)
  Ayane Mikami, Tasuku Ogita, Fu Namai, Suguru Shigemori, Takashi Sato, Takeshi Shimosato
- Journal Title
  
  Frontiers in Nutrition
  
  Volume: 7 Pages: 610946-610946
- DOI
  10.3389/fnut.2020.610946
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15480, KAKENHI-PROJECT-19KK0208
[Journal Article] Construction of genetically modified Lactococcus lactis that produces bioactive anti-interleukin-4 single-chain fragment variable2020
- Author(s)
  Namai Fu、Shigemori Suguru、Ogita Tasuku、Sato Takashi、Shimosato Takeshi
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 47 Issue: 9 Pages: 7039-7047
- DOI
  10.1007/s11033-020-05765-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19KK0208
[Journal Article] Nasally Administered Lactococcus lactis Secreting Heme Oxygenase-1 Attenuates Murine Emphysema2020
- Author(s)
  Yumoto Kentaro、Sato Takashi、Nakashima Kentaro、Namai Fu、Shigemori Suguru、Shimosato Takeshi、Kaneko Takeshi
- Journal Title
  
  Antioxidants
  
  Volume: 9 Issue: 11 Pages: 1049-1049
- DOI
  10.3390/antiox9111049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19KK0208
[Journal Article] Construction of Genetically Modified Lactococcus lactis Producing Anti-human-CTLA-4 Single-Chain Fragment Variable2020
- Author(s)
  Namai Fu、Murakami Aito、Ueda Asami、Tsukagoshi Masami、Shigemori Suguru、Ogita Tasuku、Sato Takashi、Shimosato Takeshi
- Journal Title
  
  Molecular Biotechnology
  
  Volume: 62 Issue: 11-12 Pages: 572-579
- DOI
  10.1007/s12033-020-00274-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19KK0208
[Journal Article] Ribosome-Engineered Lacticaseibacillus rhamnosus Strain GG Exhibits Cell Surface Glyceraldehyde-3-Phosphate Dehydrogenase Accumulation and Enhanced Adhesion to Human Colonic Mucin2020
- Author(s)
  Ishida Minori、Namai Fu、Shigemori Suguru、Kajikawa Shoko、Tsukagoshi Masami、Sato Takashi、Ogita Tasuku、Shimosato Takeshi
- Journal Title
  
  Applied and Environmental Microbiology
  
  Volume: 86 Issue: 20
- DOI
  10.1128/aem.01448-20
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19KK0208, KAKENHI-PROJECT-19J22578
[Journal Article] Oral administration of Flavonifractor plautii attenuates inflammatory responses in obese adipose tissue2020
- Author(s)
  Ayane Mikami, Tasuku Ogita, Fu Namai, Suguru Shigemori, Takashi Sato, Takeshi Shimosato
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 47 Issue: 9 Pages: 6717-6725
- DOI
  10.1007/s11033-020-05727-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15480, KAKENHI-PROJECT-19KK0208
[Journal Article] Oral Administration of Flavonifractor plautii Strongly Suppresses Th2 Immune Responses in Mice2020
- Author(s)
  Ogita Tasuku、Yamamoto Yoshinari、Mikami Ayane、Shigemori Suguru、Sato Takashi、Shimosato Takeshi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 379-379
- DOI
  10.3389/fimmu.2020.00379
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19KK0208, KAKENHI-PROJECT-18K19935, KAKENHI-PROJECT-20K15480
[Journal Article] Microbial therapeutics for acute colitis based on genetically modified Lactococcus lactis hypersecreting IL-1Ra in mice2020
- Author(s)
  Namai Fu、Shigemori Suguru、Ogita Tasuku、Sato Takashi、Shimosato Takeshi
- Journal Title
  
  Experimental & Molecular Medicine
  
  Volume: 52 Issue: 9 Pages: 1627-1636
- DOI
  10.1038/s12276-020-00507-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19KK0208
[Presentation] A breeding strategy of ribosome engineering for probiotics enhances the adhesion to human colonic mucin in Lacticaseibacillus rhamnosus GG2021
- Author(s)
  Namai Fu, Shigemori Suguru, Shimosato Takeshi
- Organizer
  日本農芸化学会 2021年度大会
- Data Source
  KAKENHI-PROJECT-20K20656
[Presentation] Bacterial changes associated with the rpsL gene mutation in Lacticaseibacillus rhamnosus GG2021
- Author(s)
  Masami Tsukagoshi, Fu Namai, Suguru Shigemori, Takeshi Shimosato
- Organizer
  The 11th Asian Conference on Lactic Acid Bacteria
- Data Source
  KAKENHI-PROJECT-20K20656
[Presentation] 腸内常在性乳酸菌におけるイムノバイオティック機能の強化2021
- Author(s)
  金山理佐, 生井楓，重盛駿，下里剛士
- Organizer
  酪農科学シンポジウム2021
- Data Source
  KAKENHI-PROJECT-20K20656
[Presentation] Lacticaseibacillus rhamnosus GGが高脂肪飼料断続給餌マウスに与える影響2021
- Author(s)
  鳥居創, 重盛駿, 下里剛士
- Organizer
  酪農科学シンポジウム2021
- Data Source
  KAKENHI-PROJECT-21K14959
[Presentation] 乳酸菌オリゴDNAを有効成分とする経口用微粒子がもたらす急性大腸炎の予防効果2019
- Author(s)
  重盛駿，荻田佑，下里剛士
- Organizer
  日本畜産学会第126回大会
- Data Source
  KAKENHI-PROJECT-17H03907
[Presentation] Oral delivery of probiotic ODN particles modulate the host immune system2019
- Author(s)
  Takeshi Shimosato, Suguru Shigemori, Tasuku Ogita
- Organizer
  TASP2019[The 2nd International Conference on Tropical Animal Science and Production]
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03907
[Presentation] 1.抗CTLA-4低分子抗体を産生するLactococcus lactis組換え体の構築2019
- Author(s)
  村上愛斗, 生井楓, 上田麻未，重盛駿, 荻田佑, 佐藤隆, 下里剛士
- Organizer
  2019酪農科学シンポジウム
- Data Source
  KAKENHI-PROJECT-19KK0208
[Presentation] 2.PD-1/PD-L1チェックポイントの阻害に働く乳酸菌組み換え体の構築と肺がんモデルマウスを用いた検証2019
- Author(s)
  上田麻未，生井楓，村上愛斗，重盛駿，荻田佑，佐藤隆，下里剛士
- Organizer
  2019酪農科学シンポジウム
- Data Source
  KAKENHI-PROJECT-19KK0208
[Presentation] 大腸菌ミューテーター株を用いたマウス腸内環境における適応変異解析2018
- Author(s)
  月見友哉, 重盛駿, 荒川和晴, 増田貴宏, 宮内栄治, 中東憲治, 冨田勝, 大野博司, 森浩禎, 福田真嗣
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17H06549

1. Sato Takashi (70510436)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
2. Shimosato Takeshi (00467200)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
3. 荻田佑 (50738010)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
4. 生井楓 (60893857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. 渡邉敬文 (50598216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Shigemori Suguru 重盛 駿

Research Projects

Research Products

Co-Researchers

腸内菌叢数値化法を基盤とした健全な腸内環境を安定化する乳酸菌生菌剤の創製Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of smart lactic acid bacteria

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The Optimization of Oral Lactobacillus Oligodeoxynucleotide Microparticles and the Elucidation of Immune Regulation Mechanisms via Intestinal Epithelium

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Innovative therapy for lung cancer: prophylaxis and therapy by intratracheal delivery of probiotics harboring immune checkpoint-blocking single-chain variable fragment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A quantitative comparison study of gut ecological change caused by host gene mutationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the immune mechanism using oral nanocapsule with oligodeoxynucleotides from lactic acid bacteria

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Free feeding of CpG-oligodeoxynucleotide particles prophylactically attenuates allergic airway inflammation and hyperresponsiveness in mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oral administration of Flavonifractor plautii, a bacteria increased with green tea consumption, promotes recovery from acute colitis in mice via suppression of IL-172021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Construction of genetically modified Lactococcus lactis that produces bioactive anti-interleukin-4 single-chain fragment variable2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nasally Administered Lactococcus lactis Secreting Heme Oxygenase-1 Attenuates Murine Emphysema2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Construction of Genetically Modified Lactococcus lactis Producing Anti-human-CTLA-4 Single-Chain Fragment Variable2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ribosome-Engineered Lacticaseibacillus rhamnosus Strain GG Exhibits Cell Surface Glyceraldehyde-3-Phosphate Dehydrogenase Accumulation and Enhanced Adhesion to Human Colonic Mucin2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oral administration of Flavonifractor plautii attenuates inflammatory responses in obese adipose tissue2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oral Administration of Flavonifractor plautii Strongly Suppresses Th2 Immune Responses in Mice2020

Author(s)

Journal Title

DOI

Data Source

Shigemori Suguru 重盛駿