HORAI TADASU 蓬莱政

… Alternative Names

Horai Tadasu 蓬莱政

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Researcher Number	90817826
Other IDs
Affiliation (Current)	2024: 神戸大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2024: 神戸大学, 医学部附属病院, 講師 2019 – 2022: 神戸大学, 医学部附属病院, 講師 2018: 神戸大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 52030:Psychiatry-related Except Principal Investigator Basic Section 52030:Psychiatry-related
Keywords	Principal Investigator ストレス反応生 / うつ病 / DEX-CRH負荷試験 / ストレス反応性 / 腸内細菌 Except Principal Investigator iPS細胞 / アストロサイト / MIF / 統合失調症 / エピジェネティック年齢 … More / 神経幹細胞 / SNP / 低酸素 / HIF Less

Epigenetic pathomechanisms of accelerated aging in schizophrenia
- Principal Investigator
  
  岡崎賢志
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kobe University
MIFに着目した低酸素暴露と統合失調症を結ぶ分子メカニズムの解明
- Principal Investigator
  
  岡崎賢志
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kobe University
Interventions of gut bacteria to develop preventive methods for depression.Principal Investigator
- Principal Investigator
  
  Horai Tadasu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kobe University

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Epigenetic clock analysis reveals increased plasma cystatin C levels based on DNA methylation in major depressive disorder2023
- Author(s)
  Tanifuji Takaki、Okazaki Satoshi、Otsuka Ikuo、Mouri Kentaro、Horai Tadasu、Shindo Ryota、Shirai Toshiyuki、Hishimoto Akitoyo
- Journal Title
  
  Psychiatry Research
  
  Volume: 322 Pages: 115103-115103
- DOI
  10.1016/j.psychres.2023.115103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-21K15712
[Journal Article] Ribosomal DNA gene copies are increased in blood and brain of Japanese schizophrenia patients2023
- Author(s)
  Li Sen、Otsuka Ikuo、Tanifuji Takaki、Okazaki Satoshi、Horai Tadasu、Takahashi Motonori、Kondo Takeshi、Ueno Yasuhiro、Hishimoto Akitoyo
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 1 Pages: e0280694-e0280694
- DOI
  10.1371/journal.pone.0280694
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-21K15712
[Journal Article] Accelerated epigenetic age and shortened telomere length based on DNA methylation in Nicolaides?Baraitser syndrome2022
- Author(s)
  Shinko Yutaka、Okazaki Satoshi、Otsuka Ikuo、Horai Tadasu、Kim Saehyeon、Tanifuji Takaki、Hishimoto Akitoyo
- Journal Title
  
  Molecular Genetics & Genomic Medicine
  
  Volume: 10 Issue: 3
- DOI
  10.1002/mgg3.1876
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-21K15712, KAKENHI-PROJECT-20KK0194
[Journal Article] Epigenetic clock analysis in methamphetamine dependence2022
- Author(s)
  Takemura Yukihiro、Tanifuji Takaki、Okazaki Satoshi、Shinko Yutaka、Otsuka Ikuo、Horai Tadasu、Shirai Toshiyuki、Aso Katsuro、Yamamoto Noriya、Hishimoto Akitoyo
- Journal Title
  
  Psychiatry Research
  
  Volume: 317 Pages: 114901-114901
- DOI
  10.1016/j.psychres.2022.114901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-21K15712
[Journal Article] Polymorphisms in the hypoxia inducible factor binding site of the macrophage migration inhibitory factor gene promoter in schizophrenia2022
- Author(s)
  Okazaki Satoshi、Boku Shuken、Watanabe Yuichiro、Otsuka Ikuo、Horai Tadasu、Morikawa Ryo、Kimura Atsushi、Shimmyo Naofumi、Tanifuji Takaki、Someya Toshiyuki、Hishimoto Akitoyo
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 3 Pages: e0265738-e0265738
- DOI
  10.1371/journal.pone.0265738
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-21K15712, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-20H03597
[Journal Article] Preventive effects of preoperative ramelteon on postoperative delirium in Asian elderly population: A randomized, double-blind, placebo-controlled trial, and a systematic review and meta-analysis2022
- Author(s)
  Tanifuji Takaki、Otsuka Ikuo、Okazaki Satoshi、Horai Tadasu、So Ryuhei、Shiroiwa Kyoichi、Mouri Kentaro、Tanaka Motofumi、Ohmoto Nobuko、Sora Ichiro、Hirai Midori、Fukumoto Takumi、Ku Yonson、Hishimoto Akitoyo
- Journal Title
  
  Asian Journal of Psychiatry
  
  Volume: 78 Pages: 103282-103282
- DOI
  10.1016/j.ajp.2022.103282
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-21K07545, KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-21K15712
[Journal Article] Association of Two Variable Number of Tandem Repeats in the Monoamine Oxidase A Gene Promoter with Schizophrenia2021
- Author(s)
  Tanifuji Takaki、Okazaki Satoshi、Otsuka Ikuo、Horai Tadasu、Shinko Yutaka、Kim Saehyeon、Sora Ichiro、Hishimoto Akitoyo
- Journal Title
  
  Neuropsychiatric Disease and Treatment
  
  Volume: Volume 17 Pages: 3315-3323
- DOI
  10.2147/ndt.s338854
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-21K15712, KAKENHI-PROJECT-20KK0194
[Journal Article] Searching for biomarkers in schizophrenia and psychosis: Case‐control study using capillary electrophoresis and liquid chromatography time‐of‐flight mass spectrometry and systematic review for biofluid metabolites2021
- Author(s)
  Kim Saehyeon、Okazaki Satoshi、Otsuka Ikuo、Shinko Yutaka、Horai Tadasu、Shimmyo Naofumi、Hirata Takashi、Yamaki Naruhisa、Tanifuji Takaki、Boku Shuken、Sora Ichiro、Hishimoto Akitoyo
- Journal Title
  
  Neuropsychopharmacology Reports
  
  Volume: 42 Issue: 1 Pages: 42-51
- DOI
  10.1002/npr2.12223
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02852, KAKENHI-PROJECT-21K07520, KAKENHI-PROJECT-21K15712, KAKENHI-PROJECT-20KK0194
[Journal Article] Platelet-derived growth factor BB: A potential diagnostic blood biomarker for differentiating bipolar disorder from major depressive disorder.2021
- Author(s)
  Idemoto K, Ishima T, Niitsu T, Hata T, Yoshida S, Hattori K, Horai T, Otsuka I, Yamamori H, Toda S, Kameno Y, Ota K, Oda Y, Kimura A, Hashimoto T, Mori N, Kikuchi M, Minabe Y, Hashimoto R, Hishimoto A, Nakagome K, Iyo M, Hashimoto K.
- Journal Title
  
  J Psychiatr Res
  
  Volume: 134 Pages: 48-56
- DOI
  10.1016/j.jpsychires.2020.12.051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-20H03611, KAKENHI-PROJECT-18K15484, KAKENHI-PROJECT-17K10270, KAKENHI-PROJECT-19K08066, KAKENHI-PROJECT-18KT0022, KAKENHI-PROJECT-20K07928
[Journal Article] miR-19b is elevated in peripheral blood of schizophrenic patients and attenuates proliferation of hippocampal neural progenitor cells2020
- Author(s)
  Horai T, Boku S, Okazaki S, Otsuka I, Ratta-Apha W, Mouri K, Yamaki N, Hirata T, Hishimoto A.
- Journal Title
  
  J Psychiatr Res .
  
  Volume: 131 Pages: 102-107
- DOI
  10.1016/j.jpsychires.2020.09.006
- NAID
  120006952760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20KK0194, KAKENHI-PROJECT-18K07599, KAKENHI-PROJECT-18K15483, KAKENHI-PROJECT-18K15484
[Journal Article] Chemokine Alterations in the Postmortem Brains of Suicide Completers2020
- Author(s)
  Shinko Y, Otsuka I, Okazaki S, Horai T, Boku S, Takahashi M, Ueno Y, Sora I, Hishimoto A.
- Journal Title
  
  J Psychiatr Res .
  
  Volume: 120 Pages: 29-33
- DOI
  10.1016/j.jpsychires.2019.10.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15483, KAKENHI-PROJECT-18K15484, KAKENHI-PROJECT-17H04249
[Journal Article] Unmet needs of patients with major depressive disorder ? Findings from the ‘Effectiveness of Guidelines for Dissemination and Education in Psychiatric Treatment (EGUIDE)’ project: A nationwide dissemination, education, and evaluation study2020
- Author(s)
  Iida Hitoshi、Iga Junichi、Hasegawa Naomi、（45番目）Fujimoto Michiko、et al.
- Journal Title
  
  Psychiatry and Clinical Neurosciences
  
  Volume: 74 Issue: 12 Pages: 667-669
- DOI
  10.1111/pcn.13143
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07945, KAKENHI-PROJECT-18K15522, KAKENHI-PROJECT-20H03611, KAKENHI-PROJECT-18K07564, KAKENHI-PROJECT-18K15484, KAKENHI-PROJECT-18KT0022
[Journal Article] Accelerated Extrinsic Epigenetic Aging and Increased Natural Killer Cells in Blood of Suicide Completers2020
- Author(s)
  Okazaki S, Otsuka I, Horai T, Hirata T, Takahashi M, Ueno Y, Boku S, Sora I, Hishimoto A.
- Journal Title
  
  Prog Neuropsychopharmacol Biol Psychiatry .
  
  Volume: 98 Pages: 109805-109805
- DOI
  10.1016/j.pnpbp.2019.109805
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15483, KAKENHI-PROJECT-18K15484, KAKENHI-PROJECT-17H04249
[Journal Article] Epigenetic clock analysis of blood samples from Japanese schizophrenia patients.2019
- Author(s)
  Okazaki S, Otsuka I, Numata S, Horai T, Mouri K, Boku S, Ohmori T, Sora I, Hishimoto A.
- Journal Title
  
  NPJ Schizophrenia
  
  Volume: 5 Issue: 1 Pages: 4-4
- DOI
  10.1038/s41537-019-0072-1
- NAID
  120006629323
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07599, KAKENHI-PROJECT-18K15483, KAKENHI-PROJECT-18K15484, KAKENHI-PROJECT-17H04249, KAKENHI-PROJECT-16K19765, KAKENHI-PROJECT-18H02751
[Journal Article] Major depressive disorder-associated SIRT1 locus affects the risk for suicide in women after middle age.2019
- Author(s)
  Hirata T, Otsuka I, Okazaki S, Mouri K, Horai T, Boku S, Takahashi M, Ueno Y, Sora I, Shirakawa O, Hishimoto A.
- Journal Title
  
  Psychiatry Res
  
  Volume: 278 Pages: 141-145
- DOI
  10.1016/j.psychres.2019.06.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07599, KAKENHI-PROJECT-18K15483, KAKENHI-PROJECT-18K15484, KAKENHI-PROJECT-17H04249
[Journal Article] Investigation of chromosome Y loss in men with schizophrenia.2018
- Author(s)
  Hirata T, Hishimoto A, Otsuka I, Okazaki S, Boku S, Kimura A, Horai T, Sora I.
- Journal Title
  
  Neuropsychiatr Dis Treat.
  
  Volume: 14 Pages: 2115-2122
- DOI
  10.2147/ndt.s172886
- NAID
  120006510199
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15483, KAKENHI-PROJECT-18K15484, KAKENHI-PROJECT-17H04249, KAKENHI-PROJECT-16K19765, KAKENHI-PROJECT-16H06276
[Journal Article] Mitochondrial DNA copy number of peripheral blood in bipolar disorder: The present study and a meta-analysis.2018
- Author(s)
  Yamaki N, Otsuka I, Numata S, Yanagi M, Mouri K, Okazaki S, Boku S, Horai T, Ohmori T, Shirakawa O, Sora I, Hishimoto A.
- Journal Title
  
  Psychiatry Research
  
  Volume: 269 Pages: 115-117
- DOI
  10.1016/j.psychres.2018.08.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07599, KAKENHI-PROJECT-18K15483, KAKENHI-PROJECT-18K15484, KAKENHI-PROJECT-17H04249, KAKENHI-PROJECT-16K19765
[Journal Article] Longer telomeres in elderly schizophrenia are associated with long-term hospitalization in the Japanese population.2018
- Author(s)
  Zhang Y, Hishimoto A, Otsuka I, Watanabe Y, Numata S, Yamamori H, Boku S, Horai T, Someya T, Ohmori T, Hashimoto R, Sora I.
- Journal Title
  
  J Psychiatr Res
  
  Volume: 103 Pages: 161-166
- DOI
  10.1016/j.jpsychires.2018.05.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KT0022, KAKENHI-PROJECT-18K15484, KAKENHI-PROJECT-16H05375, KAKENHI-PROJECT-17H04249, KAKENHI-PROJECT-16K15554, KAKENHI-PROJECT-16K19765, KAKENHI-PROJECT-26293261
[Presentation] 日本人統合失調症患者由来の血液試料を用いたエピジェネティクス的年齢の解析2022
- Author(s)
  岡﨑賢志、大塚郁夫、沼田周助、蓬莱政、毛利健太朗、朴秀賢、大森哲郎、曽良一郎、菱本明豊
- Organizer
  第44回日本生物学的精神医学会年会
- Data Source
  KAKENHI-PROJECT-21K07520
[Presentation] 高コルチゾール血症に伴う精神症状に対して抗精神病薬を投与中にカタトニアを呈し、ロラゼパムが奏効した一例2022
- Author(s)
  岩﨑笙、岡﨑賢志、蓬莱政、青山慎介
- Organizer
  第131回近畿精神神経学会
- Data Source
  KAKENHI-PROJECT-21K07520
[Presentation] ニコライデス・バライスター症候群におけるエピジェネティクス的年齢とテロメアの解析2022
- Author(s)
  谷藤貴紀, 新光穣, 岡崎賢志, 大塚郁夫, 蓬莱政,白井寿行,菱本明豊
- Organizer
  第44回日本生物学的精神医学会年会
- Data Source
  KAKENHI-PROJECT-21K07520
[Presentation] 精神病性障害に対するブレクスピプラゾールの使用経験2021
- Author(s)
  蓬莱政, 青山慎介, 木村敦, 新名尚史, 平田尚士, 岡崎賢志, 江口典臣, 山木愛久, 新光穣, 曽良一郎
- Organizer
  第117回日本精神神経学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07520
[Presentation] Epigenetic clock analysis of blood samples from Japanese schizophrenia patients2021
- Author(s)
  Satoshi Okazaki, Ikuo Otsuka, Shusuke Numata, Tadasu Horai, Kentaro Mouri, Shuken Boku, Tetsuro Ohmori, Ichiro Sora, Akitoyo Hishimoto
- Organizer
  7th Congress of Asian College of Neuropsychopharmacology (AsCNP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07520

1. 岡崎賢志 (70722867)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. 江口典臣 (80814566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 大塚郁夫 (40722880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. HISHIMOTO Akitoyo

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
5. BOKU Syuken

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
6. 毛利健太朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
7. 藤本美智子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 橋本亮太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 高橋健太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HORAI TADASU 蓬莱 政

Horai Tadasu 蓬莱 政

Research Projects

Research Products

Co-Researchers

Epigenetic pathomechanisms of accelerated aging in schizophrenia

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

MIFに着目した低酸素暴露と統合失調症を結ぶ分子メカニズムの解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Interventions of gut bacteria to develop preventive methods for depression.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Epigenetic clock analysis reveals increased plasma cystatin C levels based on DNA methylation in major depressive disorder2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ribosomal DNA gene copies are increased in blood and brain of Japanese schizophrenia patients2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Accelerated epigenetic age and shortened telomere length based on DNA methylation in Nicolaides?Baraitser syndrome2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epigenetic clock analysis in methamphetamine dependence2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Polymorphisms in the hypoxia inducible factor binding site of the macrophage migration inhibitory factor gene promoter in schizophrenia2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Preventive effects of preoperative ramelteon on postoperative delirium in Asian elderly population: A randomized, double-blind, placebo-controlled trial, and a systematic review and meta-analysis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association of Two Variable Number of Tandem Repeats in the Monoamine Oxidase A Gene Promoter with Schizophrenia2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Searching for biomarkers in schizophrenia and psychosis: Case‐control study using capillary electrophoresis and liquid chromatography time‐of‐flight mass spectrometry and systematic review for biofluid metabolites2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Platelet-derived growth factor BB: A potential diagnostic blood biomarker for differentiating bipolar disorder from major depressive disorder.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] miR-19b is elevated in peripheral blood of schizophrenic patients and attenuates proliferation of hippocampal neural progenitor cells2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Chemokine Alterations in the Postmortem Brains of Suicide Completers2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Unmet needs of patients with major depressive disorder ? Findings from the ‘Effectiveness of Guidelines for Dissemination and Education in Psychiatric Treatment (EGUIDE)’ project: A nationwide dissemination, education, and evaluation study2020

HORAI TADASU 蓬莱政

Horai Tadasu 蓬莱政