Nishijima Haruo 西嶌春生

Researcher Number	90858177
Other IDs
Affiliation (Current)	2025: 弘前大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2021 – 2024: 弘前大学, 医学部附属病院, 講師 2020: 弘前大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related Except Principal Investigator Basic Section 52020:Neurology-related / Basic Section 59040:Nutrition science and health science-related
Keywords	Principal Investigator 樹状突起上スパイン / シナプス可塑性 / パーキンソン病 / ジスキネジア / L-ドパ / 加齢 / 神経可塑性 / L-ドパ誘発ジスキネジア / ペランパネル / 黒質網様部 … More / カベルゴリン / アマンタジン / 直接路 / 淡蒼球内節 / レボドパ誘発ジスキネジア … More Except Principal Investigator 遅発性ジスキネジア / L-dopa誘発ジスキネジア / 遺伝性ジストニア / 老齢 / 運動由来分子 / 活動量 / exercise / プロテオーム解析 / 海馬 / 認知機能 / 老齢マウス / 運動 / dendritic spine / spiny projection neuron / tardive dyskinesia / 淡蒼球外節 / エンケファリン / ダイノルフィン / パーキンソニズム / 線条体神経細胞 / 関節路線状体神経細胞 / 直接路線条体神経細胞 / GABA / 淡蒼球内節 / 直接路神経細胞 Less

Hyperkinetic Movement Disorderの発現機序の解明とGABA放出抑制薬による治療
- Principal Investigator
  
  冨山誠彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hirosaki University
Effects of aging on synaptic plasticity in a rat model of Parkinson's diseasePrincipal Investigator
- Principal Investigator
  
  西嶌春生
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hirosaki University
運動由来分子の個体間移行による認知機能向上効果の発現メカニズム解明
- Principal Investigator
  
  古川智範
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Hirosaki University
The role of plastic changes of striatal spiny projection neurons in the development of tardive dyskinesia
- Principal Investigator
  
  Tomiyama Masahiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hirosaki University
Pathophysiology and treatment for levodopa-induced dyskinesia in a rat model of Parkinson's diseasePrincipal Investigator
- Principal Investigator
  
  Nishijima Haruo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hirosaki University

All 2024 2023 2022 2021

All Journal Article Presentation Book

[Book] 「薬剤誘発性ジスキネジアと淡蒼球内節に関する研究動向」in 「Annual Review 神経 2024」2024
- Author(s)
  西嶌春生，中村崇志，冨山誠彦
- Total Pages
  6
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23K06941
[Journal Article] GABA storage and release from direct pathway neurons account for the enhanced short-duration response of L-dopa in Parkinson's disease2024
- Author(s)
  Nishijima Haruo、Tomiyama Masahiko
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 456 Pages: 122844-122844
- DOI
  10.1016/j.jns.2023.122844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06941, KAKENHI-PROJECT-21K07410
[Journal Article] Axon terminal hypertrophy of striatal projection neurons with levodopa-induced dyskinesia priming2023
- Author(s)
  Nakamura Takashi、Nishijima Haruo、Mori Fumiaki、Kinoshita Iku、Kon Tomoya、Suzuki Chieko、Wakabayashi Koichi、Tomiyama Masahiko
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 17 Pages: 1169336-1169336
- DOI
  10.3389/fnins.2023.1169336
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06802, KAKENHI-PROJECT-23K06941, KAKENHI-PROJECT-21K07410, KAKENHI-PROJECT-23K24209
[Journal Article] Altered amantadine effects after repetitive treatment for l-dopa-induced involuntary movements in a rat model of Parkinson’s disease2023
- Author(s)
  Murakami Yoshiki、Nishijima Haruo、Nakamura Takashi、Furukawa Tomonori、Kinoshita Iku、Kon Tomoya、Suzuki Chieko、Tomiyama Masahiko
- Journal Title
  
  Neuroscience Letters
  
  Volume: 806 Pages: 137248-137248
- DOI
  10.1016/j.neulet.2023.137248
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11747, KAKENHI-PROJECT-21K07410
[Journal Article] Cabergoline, a long-acting dopamine agonist, attenuates L-dopa-induced dyskinesia without L-dopa sparing in a rat model of Parkinson’s disease2022
- Author(s)
  Nishijima Haruo、Mori Fumiaki、Kimura Tamaki、Miki Yasuo、Kinoshita Iku、Nakamura Takashi、Kon Tomoya、Suzuki Chieko、Wakabayashi Koichi、Tomiyama Masahiko
- Journal Title
  
  Neuroscience Research
  
  Volume: - Pages: 93-97
- DOI
  10.1016/j.neures.2022.02.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02533, KAKENHI-PROJECT-20K16570
[Presentation] パーキンソン病モデルラットにおけるアマンタジンの治療効果は反復投与により変動する2022
- Author(s)
  村上佳生，西嶌春生，中村崇志，木下郁，今智矢，鈴木千恵子，冨山誠彦
- Organizer
  第159回弘前医学会例会
- Data Source
  KAKENHI-PROJECT-20K16570
[Presentation] パーキンソン病モデルラットにおけるアマンタジンの治療効果は反復投与により変動する2022
- Author(s)
  西嶌春生，村上佳生，中村崇志，木下郁，引地浩基，今智矢，鈴木千恵子，冨山誠彦
- Organizer
  第16回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-20K16570
[Presentation] レボドパ誘発ジスキネジアに対するグルタミン酸受容体拮抗薬の効果の検討2021
- Author(s)
  西嶌春生
- Organizer
  令和2年度弘前大学機関研究・弘前大学異分野連携型若手研究支援事業・弘前大学グロウカル（Grow×Local）ファンド採択者による合同研究成果発表会
- Data Source
  KAKENHI-PROJECT-20K16570
[Presentation] 遅発性ジスキネジアモデルにおける線条体におけるダイノルフィンの変化2021
- Author(s)
  西嶌春生
- Organizer
  日本パーキンソン病・運動障害疾患学会
- Data Source
  KAKENHI-PROJECT-21K07410

1. Tomiyama Masahiko (40311542)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 森文秋 (60200383)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. 古川智範 (60402369)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 中村崇志 (00880014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 山田順子 (30334965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 下山修司 (60736370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 小枝周平 (00455734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 富山誠彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 若林孝一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 三木康生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 今智矢

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishijima Haruo 西嶌 春生

Research Projects

Research Products

Co-Researchers

Hyperkinetic Movement Disorderの発現機序の解明とGABA放出抑制薬による治療

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of aging on synaptic plasticity in a rat model of Parkinson's diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

運動由来分子の個体間移行による認知機能向上効果の発現メカニズム解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of plastic changes of striatal spiny projection neurons in the development of tardive dyskinesia

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathophysiology and treatment for levodopa-induced dyskinesia in a rat model of Parkinson's diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 「薬剤誘発性ジスキネジアと淡蒼球内節に関する研究動向」in 「Annual Review 神経 2024」2024

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] GABA storage and release from direct pathway neurons account for the enhanced short-duration response of L-dopa in Parkinson's disease2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Axon terminal hypertrophy of striatal projection neurons with levodopa-induced dyskinesia priming2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Altered amantadine effects after repetitive treatment for l-dopa-induced involuntary movements in a rat model of Parkinson’s disease2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cabergoline, a long-acting dopamine agonist, attenuates L-dopa-induced dyskinesia without L-dopa sparing in a rat model of Parkinson’s disease2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] パーキンソン病モデルラットにおけるアマンタジンの治療効果は反復投与により変動する2022

Author(s)

Organizer

Data Source

[Presentation] パーキンソン病モデルラットにおけるアマンタジンの治療効果は反復投与により変動する2022

Author(s)

Organizer

Data Source

[Presentation] レボドパ誘発ジスキネジアに対するグルタミン酸受容体拮抗薬の効果の検討2021

Author(s)

Organizer

Data Source

[Presentation] 遅発性ジスキネジアモデルにおける線条体におけるダイノルフィンの変化2021

Author(s)

Organizer

Data Source

Nishijima Haruo 西嶌春生