Oike Akira 大池輝

Researcher Number	90884552
Other IDs
Affiliation (Current)	2026: 熊本大学, 発生医学研究所, 助教
Affiliation (based on the past Project Information) *help	2025: 熊本大学, 発生医学研究所, 助教 2023: 熊本大学, 発生医学研究所, 助教 2021 – 2022: 東北大学, 医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 44020:Developmental biology-related / Basic Section 56040:Obstetrics and gynecology-related
Keywords	Principal Investigator 器官形成 / ヒト胚モデル / ゲノムインプリンティング / 低出生体重児 / 胎盤栄養膜幹(TS)細胞 / ヒト胚着床 / 胎盤オルガノイド / 低出生体重児 (SGA) / 三次元胎盤モデル / 栄養膜幹細胞 / 三次元ヒト胎盤モデル / ヒト栄養膜幹細胞 / 低出生体重児(SGA)

新規ヒト胚モデルで器官形成期のヒトの発生を理解するPrincipal Investigator
- Principal Investigator
  
  大池輝
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Kumamoto University
Epigenomic variation in the placenta of SGA infants and the generation of SGA-specific placental modelsPrincipal Investigator
- Principal Investigator
  
  Oike Akira
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kumamoto University
  Tohoku University

All 2024 2023 2022 2021

All Journal Article Presentation Book

[Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021
- Author(s)
  大池輝, 小林枝里, 小林記緒, 柴田峻, 岡江寛明, 北村茜, 宮内尚子, 有馬隆博
- Total Pages
  5
- Publisher
  北隆館／ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-21K16782
[Journal Article] Trophoblast stem cell-based organoid models of the human placental barrier2024
- Author(s)
  Hori Takeshi、Okae Hiroaki、Shibata Shun、Kobayashi Norio、Kobayashi Eri H.、Oike Akira、Sekiya Asato、Arima Takahiro、Kaji Hirokazu
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 1-1
- DOI
  10.1038/s41467-024-45279-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K04852, KAKENHI-PROJECT-22K18936, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PROJECT-23K26514, KAKENHI-PLANNED-19H05757, KAKENHI-PROJECT-24K18126
[Journal Article] Modeling embryo-endometrial interface recapitulating human embryo implantation2024
- Author(s)
  Shibata Shun、Endo Shun、Nagai Luis A. E.、H. Kobayashi Eri、Oike Akira、Kobayashi Norio、Kitamura Akane、Hori Takeshi、Nashimoto Yuji、Nakato Ryuichiro、Hamada Hirotaka、Kaji Hirokazu、Kikutake Chie、Suyama Mikita、Saito Masatoshi、Yaegashi Nobuo、Okae Hiroaki、Arima Takahiro
- Journal Title
  
  Science Advances
  
  Volume: 10 Issue: 8
- DOI
  10.1126/sciadv.adi4819
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18936, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PROJECT-21H03803, KAKENHI-PROJECT-23K26514, KAKENHI-PLANNED-19H05757
[Journal Article] CRISPR screening in human trophoblast stem cells reveals both shared and distinct aspects of human and mouse placental development2023
- Author(s)
  Takanori Shimizu*, Akira Oike*, Eri H. Kobayashi*, Asato Sekiya, Norio Kobayashi, Shun Shibata, Hirotaka Hamada, Masatoshi Saito, Nobuo Yaegashi, Mikita Suyama, Takahiro Arima, and Hiroaki Okae. *T.S., A.O., and E.H.K. contributed equally to this work.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 51
- DOI
  10.1073/pnas.2311372120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08838, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PLANNED-19H05757
[Journal Article] The microRNA cluster C19MC confers differentiation potential into trophoblast lineages upon human pluripotent stem cells2022
- Author(s)
  Kobayashi Norio、Okae Hiroaki、Hiura Hitoshi、Kubota Naoto、Kobayashi Eri H.、Shibata Shun、Oike Akira、Hori Takeshi、Kikutake Chie、Hamada Hirotaka、Kaji Hirokazu、Suyama Mikita、Bortolin-Cavaill? Marie-Line、Cavaill? J?r?me、Arima Takahiro
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 3071-3071
- DOI
  10.1038/s41467-022-30775-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K04852, KAKENHI-PROJECT-22K18936, KAKENHI-PROJECT-21K15098, KAKENHI-PROJECT-21K16782, KAKENHI-PROJECT-21H04834, KAKENHI-PROJECT-21H03072, KAKENHI-PROJECT-21K19546, KAKENHI-PROJECT-22K15117, KAKENHI-ORGANIZER-19H05749, KAKENHI-PLANNED-19H05757
[Presentation] CRISPRスクリーニングによるヒト栄養膜細胞分化機構の解析2023
- Author(s)
  大池　輝
- Organizer
  新学術領域「全能性プログラム」若手勉強会 2023
- Data Source
  KAKENHI-PROJECT-21K16782
[Presentation] ヒト栄養膜細胞を用いたシンシチンの研究2022
- Author(s)
  大池　輝
- Organizer
  第3回「全能性プログラム」若手勉強会
- Data Source
  KAKENHI-PROJECT-21K16782
[Presentation] Distinct functions of human Syncytins at the maternal-fetal interface Ape-specific endogenous retrovirus Syncytin-1 mediates cell fusion at the maternal-fetal interface2022
- Author(s)
  Oike Akira
- Organizer
  The International Symposium "Totipotency and Germ Cell Development"
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16782

1. 堀武志

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
2. 梶弘和

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
3. 柴田峻

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 小林枝里

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Oike Akira 大池 輝

Research Projects

Research Products

Co-Researchers

新規ヒト胚モデルで器官形成期のヒトの発生を理解するPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Epigenomic variation in the placenta of SGA infants and the generation of SGA-specific placental modelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] ヒトTS細胞を用いた胎盤疾患モデルの構築2021

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Trophoblast stem cell-based organoid models of the human placental barrier2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Modeling embryo-endometrial interface recapitulating human embryo implantation2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CRISPR screening in human trophoblast stem cells reveals both shared and distinct aspects of human and mouse placental development2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The microRNA cluster C19MC confers differentiation potential into trophoblast lineages upon human pluripotent stem cells2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] CRISPRスクリーニングによるヒト栄養膜細胞分化機構の解析2023

Author(s)

Organizer

Data Source

[Presentation] ヒト栄養膜細胞を用いたシンシチンの研究2022

Author(s)

Organizer

Data Source

[Presentation] Distinct functions of human Syncytins at the maternal-fetal interface Ape-specific endogenous retrovirus Syncytin-1 mediates cell fusion at the maternal-fetal interface2022

Author(s)

Organizer

Data Source

Oike Akira 大池輝