nakajima shogo 中嶋章悟

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NAKAJIMA SHOGO 中嶋章悟

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Researcher Number	90895509
Other IDs
Affiliation (Current)	2026: 麻布大学, 獣医学部, 特命研究員 2026: 医療法人さわらび会福祉村病院長寿医学研究所, 長寿医学研究所, 研究員
Affiliation (based on the past Project Information) *help	2024: 麻布大学, 獣医学部, 特命研究員 2021 – 2023: 医療法人さわらび会福祉村病院長寿医学研究所, 長寿医学研究所, 研究員
Review Section/Research Field	Principal Investigator Basic Section 49060:Virology-related
Keywords	Principal Investigator 薬剤耐性変異 / 酵素 / HBV / NNRTI / 非核酸系逆転写阻害剤 / ポリメラーゼ / B型肝炎ウイルス

Analysis of the relationship between hepatitis B virus polymerase and non-nucleoside reverse transcriptase inhibitorsPrincipal Investigator
- Principal Investigator
  
  NAKAJIMA SHOGO
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Azabu University
  Choju Medical Institute, Fukushimura Hospital.

All 2025 2024 2023 2022 2021

All Journal Article Presentation Patent

[Journal Article] Potent SARS-CoV-2 3C-like protease inhibitor (+)-eupenoxide-3,6-diketone (IC50: 0.048μM) was synthesized based on (+)-eupenoxide; lead from (+)-eupenoxide analogs study by endophytic fermentation2025
- Author(s)
  Maehara Shoji、Kumamoto Moeka、Nakajima Shogo、Hieda Yuhzo、Watashi Koichi、Hata Toshiyuki
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 79 Issue: 2 Pages: 357-370
- DOI
  10.1007/s11418-024-01874-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15458, KAKENHI-PROJECT-23K06189
[Journal Article] Isolation, structural determination, and antiviral activities of a novel alanine-conjugated polyketide from Talaromyces sp.2024
- Author(s)
  Mosu Nozomi、Yasukochi Mitsuki、Nakajima Shogo、Nakamura Kou、Ogata Masaya、Iguchi Keita、Kanno Kazuki、Ishikawa Tomohiro、Sugita Kazutoshi、Murakami Hironobu、Kuramochi Kouji、Saito Tatsuo、Takeda Shiro、Watashi Koichi、Fujino Kan、Kamisuki Shinji
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 77 Issue: 8 Pages: 499-505
- DOI
  10.1038/s41429-024-00740-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K05299, KAKENHI-PROJECT-21K15458
[Journal Article] Anti-SARS-CoV-2 Agents in Artemisia Endophytic Fungi and Their Abundance in Artemisia?vulgaris Tissue2023
- Author(s)
  Maehara Shoji、Nakajima Shogo、Watashi Koichi、Agusta Andria、Kikuchi Misato、Hata Toshiyuki、Takayama Kento
- Journal Title
  
  Journal of Fungi
  
  Volume: 9 Issue: 9 Pages: 905-905
- DOI
  10.3390/jof9090905
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15458, KAKENHI-PROJECT-23K06189, KAKENHI-PROJECT-20H03499
[Journal Article] Identification of IMP Dehydrogenase as a Potential Target for Anti-Mpox Virus Agents2023
- Author(s)
  Hishiki T、Morita T、Akazawa D、Ohashi H、Park E、Kataoka M、Mifune J、Shionoya K、Tsuchimoto K、Ojima S、Azam Aa H、Nakajima S、Kawahara M、Yoshikawa T、Shimojima M、Kiga K、Maeda K、Suzuki T、Ebihara H、Takahashi Y、Watashi K.
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 11 Issue: 4
- DOI
  10.1128/spectrum.00566-23
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15458, KAKENHI-PROJECT-22KJ2816, KAKENHI-PROJECT-20K07532, KAKENHI-PROJECT-23K27415, KAKENHI-PROJECT-20H03499, KAKENHI-PROJECT-23K21171, KAKENHI-PROJECT-21K19666, KAKENHI-PROJECT-22K20780
[Journal Article] Antiviral Activity of Micafungin and Its Derivatives against SARS-CoV-2 RNA Replication2023
- Author(s)
  Nakajima Shogo、Ohashi Hirofumi、Akazawa Daisuke、Torii Shiho、Suzuki Rigel、Fukuhara Takasuke、Watashi Koichi
- Journal Title
  
  Viruses
  
  Volume: 15 Issue: 2 Pages: 452-452
- DOI
  10.3390/v15020452
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15458, KAKENHI-PROJECT-20K16267, KAKENHI-PROJECT-20H03499
[Journal Article] Potential Anti-Mpox Virus Activity of Atovaquone, Mefloquine, and Molnupiravir, and Their Potential Use as Treatments2023
- Author(s)
  Akazawa D、Ohashi H、Hishiki T、Morita T、Iwanami S、Kim KS、Jeong YD、Park ES、Kataoka M、Shionoya K、Mifune J、Tsuchimoto K、Ojima S、Azam AH、Nakajima S、Park H、Yoshikawa T、Shimojima M、Kiga K、Iwami S、Maeda K、Suzuki T、Ebihara H、Takahashi Y、Watashi K
- Journal Title
  
  The Journal of Infectious Diseases
  
  Volume: Online ahead of print. Issue: 5 Pages: 591-603
- DOI
  10.1093/infdis/jiad058
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07532, KAKENHI-PROJECT-21K15458, KAKENHI-PROJECT-22KJ2816, KAKENHI-PROJECT-23K27415, KAKENHI-PROJECT-23K21171, KAKENHI-PROJECT-21K19666, KAKENHI-PROJECT-20H03499, KAKENHI-PROJECT-22K20780
[Journal Article] Antiviral activity of ciclesonide acetal derivatives blocking SARS-CoV-2 RNA replication2022
- Author(s)
  Tsuji Genichiro、Nakajima Shogo、Watashi Koichi、Torii Shiho、Suzuki Rigel、Fukuhara Takasuke、Ohoka Nobumichi、Inoue Takao、Demizu Yosuke
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 149 Issue: 3 Pages: 81-84
- DOI
  10.1016/j.jphs.2022.04.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05320, KAKENHI-PROJECT-21K15458, KAKENHI-PROJECT-21H02736, KAKENHI-PROJECT-20H03499
[Journal Article] Biochemical and Structural Properties of Entecavir-Resistant Hepatitis B Virus Polymerase with L180M/M204V Mutations2021
- Author(s)
  Nakajima Shogo、Watashi Koichi、Kato Takanobu、Muramatsu Masamichi、Wakita Takaji、Tamura Noriko、Hattori Shin-ichiro、Maeda Kenji、Mitsuya Hiroaki、Yasutake Yoshiaki、Toyoda Tetsuya
- Journal Title
  
  Journal of Virology
  
  Volume: 95 Issue: 16
- DOI
  10.1128/jvi.02401-20
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07522, KAKENHI-PROJECT-21K15458
[Journal Article] Evaluating cepharanthine analogues as natural drugs against SARS‐CoV‐22021
- Author(s)
  Hijikata Atsushi、Shionyu‐Mitsuyama Clara、Nakae Setsu、Shionyu Masafumi、Ota Motonori、Kanaya Shigehiko、Hirokawa Takatsugu、Nakajima Shogo、Watashi Koichi、Shirai Tsuyoshi
- Journal Title
  
  FEBS Open Bio
  
  Volume: 12 Issue: 1 Pages: 285-294
- DOI
  10.1002/2211-5463.13337
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12211, KAKENHI-PROJECT-18H03331, KAKENHI-PROJECT-21K15458, KAKENHI-PLANNED-20H05932, KAKENHI-PROJECT-23K21721, KAKENHI-PROJECT-20H03499
[Patent] フラノクマリン誘導体およびその用途2024
- Inventor(s)
  渡辺賢二長田裕之渡邉正悟川谷誠中嶋章悟日紫喜隆行渡士幸一
- Industrial Property Rights Holder
  渡辺賢二長田裕之渡邉正悟川谷誠中嶋章悟日紫喜隆行渡士幸一
- Industrial Property Rights Type
  特許
- Filing Date
  2024
- Overseas
- Data Source
  KAKENHI-PROJECT-21K15458
[Presentation] 核内受容体NR4A1リガンドの探索とその抗ウイルス活性2025
- Author(s)
  丸山華凜, 中村洸, 大橋啓史, 中嶋章悟, 山内皓稀, 模素希, 村上裕信, 岡田麻衣子, 倉持幸司, 渡士幸一, 紙透伸治
- Organizer
  日本農芸化学会2025年度大会
- Data Source
  KAKENHI-PROJECT-21K15458
[Presentation] サンショウエンドファイトの同定研究と培養エキスの抗SARS-CoV-2活性2025
- Author(s)
  吉武聖利望, 中嶋章悟, 渡士幸一, 秦季之, 前原昭次
- Organizer
  日本薬学会第145回年会
- Data Source
  KAKENHI-PROJECT-21K15458
[Presentation] コロナウイルス不活化剤としてのレモングラスオイルの検討2024
- Author(s)
  中嶋章悟, 紙透伸治, 渡士幸一
- Organizer
  日本生薬学会第70回年会
- Data Source
  KAKENHI-PROJECT-21K15458
[Presentation] コロナウイルス不活化剤としてのレモングラス精油の検討2024
- Author(s)
  中嶋章悟, 紙透伸治, 渡士幸一
- Organizer
  第27回日本アロマセラピー学会学術総会、第10回日本ハーブ療法研究会学術講演会　合同大会
- Data Source
  KAKENHI-PROJECT-21K15458
[Presentation] ニチニチソウエンドファイト産生物とその誘導体のSARS-CoV-2増殖抑制活性およびαグルコシダーゼ阻害活性2024
- Author(s)
  前原昭次, 熊本萌香, 中嶋章悟, 稗田雄三, 柴田紗知, 渡士幸一, 秦季之
- Organizer
  植物微生物研究会第33回研究交流会
- Data Source
  KAKENHI-PROJECT-21K15458
[Presentation] エンテカビル耐性B型肝炎ウイルスポリメラーゼの生化学的および構造学的性質2022
- Author(s)
  中嶋章悟, 渡士幸一, 加藤孝宣, 村松正道, 脇田隆字, 安武義晃, 豊田哲也.
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K15458
[Presentation] Biochemical and structural properties of entecavir-resistant hepatitis B virus polymerase2022
- Author(s)
  Nakajima S, Watashi K, Kato T, Muramatsu M, Wakita T, Yasutake Y, Toyoda T.
- Organizer
  2022 International Meeting on Molecular Biology of Hepatitis B Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15458
[Presentation] 新型コロナウイルス感染細胞実験を用いたハイスループット化合物スクリーニング系の構築2021
- Author(s)
  中嶋章悟、大橋啓史、竹田誠、渡士幸一
- Organizer
  第44回 (2021) 日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K15458

1. KAMISUKI Shinji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. HISHIKI Takayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. SHIONYU Masafumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 服部真一朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 安武義晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 出水庸介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 土方敦司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

nakajima shogo 中嶋 章悟

NAKAJIMA SHOGO 中嶋 章悟

Research Projects

Research Products

Co-Researchers

Analysis of the relationship between hepatitis B virus polymerase and non-nucleoside reverse transcriptase inhibitorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Potent SARS-CoV-2 3C-like protease inhibitor (+)-eupenoxide-3,6-diketone (IC50: 0.048μM) was synthesized based on (+)-eupenoxide; lead from (+)-eupenoxide analogs study by endophytic fermentation2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Isolation, structural determination, and antiviral activities of a novel alanine-conjugated polyketide from Talaromyces sp.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti-SARS-CoV-2 Agents in Artemisia Endophytic Fungi and Their Abundance in Artemisia?vulgaris Tissue2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of IMP Dehydrogenase as a Potential Target for Anti-Mpox Virus Agents2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antiviral Activity of Micafungin and Its Derivatives against SARS-CoV-2 RNA Replication2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Potential Anti-Mpox Virus Activity of Atovaquone, Mefloquine, and Molnupiravir, and Their Potential Use as Treatments2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antiviral activity of ciclesonide acetal derivatives blocking SARS-CoV-2 RNA replication2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Biochemical and Structural Properties of Entecavir-Resistant Hepatitis B Virus Polymerase with L180M/M204V Mutations2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluating cepharanthine analogues as natural drugs against SARS‐CoV‐22021

Author(s)

Journal Title

DOI

Data Source

[Patent] フラノクマリン誘導体およびその用途2024

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] 核内受容体NR4A1リガンドの探索とその抗ウイルス活性2025

Author(s)

Organizer

Data Source

[Presentation] サンショウエンドファイトの同定研究と培養エキスの抗SARS-CoV-2活性2025

Author(s)

Organizer

Data Source

[Presentation] コロナウイルス不活化剤としてのレモングラスオイルの検討2024

Author(s)

Organizer

Data Source

[Presentation] コロナウイルス不活化剤としてのレモングラス精油の検討2024

Author(s)

Organizer

Data Source

[Presentation] ニチニチソウエンドファイト産生物とその誘導体のSARS-CoV-2増殖抑制活性およびαグルコシダーゼ阻害活性2024

Author(s)

nakajima shogo 中嶋章悟

NAKAJIMA SHOGO 中嶋章悟