Kobayashi Satomi 小林理美

Researcher Number	90999062
Other IDs
Affiliation (Current)	2026: 日本大学, 歯学部, 助教
Affiliation (based on the past Project Information) *help	2024 – 2026: 日本大学, 歯学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 57010:Oral biological science-related Except Principal Investigator Medium-sized Section 57:Oral science and related fields / Basic Section 57010:Oral biological science-related
Keywords	Except Principal Investigator c-Fos / 痛み / 痛み関連行動 / 記憶 / ケミカルジェネティクス / 島皮質 / 口腔顔面痛 / 中枢神経 / 鎮痛薬

アロディニアによる島皮質感覚応答ニューロンの可塑的変化の解明Principal Investigator
- Principal Investigator
  
  小林理美
- Project Period (FY)
  2026 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Nihon University
鎮痛薬によってニューロン活動が変調する脳領域の解明
- Principal Investigator
  
  藤田智史
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Nihon University
Exploration of insulocortical neurons relating to memory consolication of orofacial pain
- Principal Investigator
  
  KOBAYASHI Masayuki
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Nihon University

All 2025 2024 2023

All Journal Article Presentation

[Journal Article] Opioidergic activation of the descending pain inhibitory system underlies placebo analgesia2025
- Author(s)
  Neyama H, Wu Y, Nakaya Y, Kato S, Miyamichi K, Matsushita N, Mashimo T, Miyasaka Y, Dai Y, Noguchi K, Watanabe Y, Kobayashi M, Kobayashi K, Cui YL
- Journal Title
  
  Science Advances
  
  Volume: 11(3) Issue: 3
- DOI
  10.1126/sciadv.adp8494
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23H00367, KAKENHI-PROJECT-23K24515, KAKENHI-PROJECT-23K18366, KAKENHI-PROJECT-23K24704, KAKENHI-PROJECT-24K02867, KAKENHI-PROJECT-23K09363
[Journal Article] Regulation of nociception by LTP of IPSCs from insular cortical parvalbumin-immunopositive neurons to pyramidal neurons.2025
- Author(s)
  Kobayashi S, Osaki H, Kato S, Kobayashi K, Kobayashi M
- Journal Title
  
  PAIN
  
  Volume: - Issue: 8 Pages: 1823-1835
- DOI
  10.1097/j.pain.0000000000003518
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24515, KAKENHI-PROJECT-23K18366
[Journal Article] Cortical nitric oxide required for presynaptic long-term potentiation in the insular cortex2024
- Author(s)
  Yamamoto Kiyofumi、Chen Qi-Yu、Zhou Zhaoxiang、Kobayashi Masayuki、Zhuo Min
- Journal Title
  
  Philosophical Transactions of the Royal Society B: Biological Sciences
  
  Volume: 379 Issue: 1906 Pages: 20230475-20230475
- DOI
  10.1098/rstb.2023.0475
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24515, KAKENHI-PROJECT-23K18366, KAKENHI-PROJECT-23K09129
[Journal Article] Reduction in calcium responses to whisker stimulation in the primary somatosensory and motor cortices of the model mouse with trigeminal neuropathic pain.2024
- Author(s)
  Kitano K, O’Hashi K, Fujita S, Kobayashi M
- Journal Title
  
  J Oral Biosci
  
  Volume: 66 Issue: 3 Pages: 587-593
- DOI
  10.1016/j.job.2024.06.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24515, KAKENHI-PROJECT-23K18366
[Journal Article] Activation of multiple neuromodulatory systems in alert rats acquiring conditioned taste aversion revealed by positron emission tomography2024
- Author(s)
  Kobayashi Satomi、Kajiwara Mie、Cui Yilong、Sako Takeo、Sasabe Tetsuya、Hayashinaka Emi、Wada Yasuhiro、Kobayashi Masayuki
- Journal Title
  
  Brain Research
  
  Volume: 1822 Pages: 148617-148617
- DOI
  10.1016/j.brainres.2023.148617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K18366, KAKENHI-PROJECT-23K24515
[Journal Article] Functional roles of descending projections from the cerebral cortex to the trigeminal spinal nucleus caudalis in orofacial nociceptive information processing.2024
- Author(s)
  Kobayashi M, Nakaya Y, Kobayashi S
- Journal Title
  
  J Oral Biosci
  
  Volume: 66 Issue: 2 Pages: 304-307
- DOI
  10.1016/j.job.2024.05.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24515, KAKENHI-PROJECT-23K18366
[Journal Article] P2X receptor- and postsynaptic NMDA receptor-mediated long-lasting facilitation of inhibitory synapses in the rat insular cortex2024
- Author(s)
  Yamamoto Kiyofumi、Kosukegawa Satoshi、Kobayashi Masayuki
- Journal Title
  
  Neuropharmacology
  
  Volume: 245 Pages: 109817-109817
- DOI
  10.1016/j.neuropharm.2023.109817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K18366, KAKENHI-PROJECT-23K24515, KAKENHI-PROJECT-23K09129
[Journal Article] Insulin potentiates inhibitory synaptic currents between fast-spiking and pyramidal neurons in the rat insular cortex2023
- Author(s)
  Nakaya Yuka、Kosukegawa Satoshi、Kobayashi Satomi、Hirose Kensuke、Kitano Kouhei、Mayahara Kotoe、Takei Hiroki、Motoyoshi Mitsuru、Kobayashi Masayuki
- Journal Title
  
  Neuropharmacology
  
  Volume: 238 Pages: 109649-109649
- DOI
  10.1016/j.neuropharm.2023.109649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K18366, KAKENHI-PROJECT-23K09363, KAKENHI-PROJECT-23K24515
[Presentation] Descending pathway from the insular cortex to the brainstem nuclei facilitates nociception in orofacial area.2025
- Author(s)
  Nakaya Y, Kobayashi M
- Organizer
  Oral Neuroscience 2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18366
[Presentation] Cortical responses to electrical stimulation of the periodontal ligament in mice.2024
- Author(s)
  Okuma R, Kobayashi S, Kobayashi S, Arai Y, Kobayashi M, Fujita S
- Organizer
  Neuroscience 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18366
[Presentation] Activation of insular cortical projections to the parabrachial nucleus regulates pain-related behaviors in rats.2024
- Author(s)
  Nakaya Y, Hirose K, Kobayashi S, Osaki H, Kobayashi M
- Organizer
  Neuroscience 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18366
[Presentation] Ghrelin regulates excitatory synaptic transmission from the insular cortex to the nucleus of the solitary tract in the rat.2024
- Author(s)
  Wakabayashi A, Nakaya Y, Kobayashi M
- Organizer
  Neuroscience 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18366
[Presentation] Regulation of nociception in orofacial area by long-term potentiation of inhibitory synapses in the insular cortex using optogenetics.2024
- Author(s)
  Kobayashi S, Osaki H, Fujita S, Kato S, Kobayashi K, Kobayashi M
- Organizer
  Neuroscience 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18366
[Presentation] 眼窩下神経結紮によるバレル領野の可塑的変化2023
- Author(s)
  北野晃平、大橋一徳、小林真之
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K18366
[Presentation] 島皮質 parvalbumin陽性細胞→錐体細胞シナプスにおける長期増強による疼痛コントロール2023
- Author(s)
  小林理美、藤田智史、小林真之
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K18366
[Presentation] マウスの口腔顔面領域に対する温度刺激時の大脳皮質応答2023
- Author(s)
  大熊理沙子、小林理美、藤田智史、小林真之
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K18366
[Presentation] 光遺伝学的手法による島皮質から腕傍核への侵害情報入力の投射様式2023
- Author(s)
  廣瀬健佑、中谷有香、松村幸恵、小林真之
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K18366
[Presentation] 社会的敗北ストレス経験による中脳水道周囲灰白質および三叉神経脊髄路核尾側亜核の神経活動変化2023
- Author(s)
  川﨑詩織、小林真之
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K18366
[Presentation] 上下顎の歯痛は脳内でどのように区別されているのか？2023
- Author(s)
  大橋一徳、小林真之
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K18366
[Presentation] The activation of insular cortical projections to the trigeminal spinal subnucleus caudalis regulates pain-related behaviors in rats2023
- Author(s)
  Yuka Nakaya, Kiyofumi Yamamoto, Masayuki Kobayashi
- Organizer
  Society for Neuroscience 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18366
[Presentation] 大脳皮質島領野における口腔顔面領域の痛覚異常を制御する興奮性および抑制性シナプス長期可塑性2023
- Author(s)
  山本清文、小林真之
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K18366
[Presentation] グレリンは島皮質から延髄孤束核の抑制性ニューロンに対するシナプス応答を減弱する2023
- Author(s)
  若林杏美、中谷有香、堤友美、小林真之
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K18366
[Presentation] インスリンは PI3K-PKB/AKtシグナル経路を介してラット島皮質抑制性シナプス伝達を促進する2023
- Author(s)
  中谷有香、小林理美、廣瀬健佑、北野晃平、小林真之
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K18366
[Presentation] 島皮質からの下行性投射による疼痛制御機構2023
- Author(s)
  小林真之
- Organizer
  日本線維筋痛症・慢性疼痛学会　第13回学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K18366

1. KOBAYASHI Masayuki (00300830)

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results
2. 藤田智史 (00386096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 尾崎弘展 (30747697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 中谷有香 (60781391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
5. 加藤成樹 (90443879)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. YAMAMOTO Kiyofumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 小林和人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 阿部学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 小林憲太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 真下知士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kobayashi Satomi 小林 理美

Research Projects

Research Products

Co-Researchers

アロディニアによる島皮質感覚応答ニューロンの可塑的変化の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

鎮痛薬によってニューロン活動が変調する脳領域の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploration of insulocortical neurons relating to memory consolication of orofacial pain

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Opioidergic activation of the descending pain inhibitory system underlies placebo analgesia2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of nociception by LTP of IPSCs from insular cortical parvalbumin-immunopositive neurons to pyramidal neurons.2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cortical nitric oxide required for presynaptic long-term potentiation in the insular cortex2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reduction in calcium responses to whisker stimulation in the primary somatosensory and motor cortices of the model mouse with trigeminal neuropathic pain.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activation of multiple neuromodulatory systems in alert rats acquiring conditioned taste aversion revealed by positron emission tomography2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional roles of descending projections from the cerebral cortex to the trigeminal spinal nucleus caudalis in orofacial nociceptive information processing.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] P2X receptor- and postsynaptic NMDA receptor-mediated long-lasting facilitation of inhibitory synapses in the rat insular cortex2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Insulin potentiates inhibitory synaptic currents between fast-spiking and pyramidal neurons in the rat insular cortex2023

Author(s)

Journal Title

DOI

Data Source

[Presentation] Descending pathway from the insular cortex to the brainstem nuclei facilitates nociception in orofacial area.2025

Author(s)

Organizer

Data Source

[Presentation] Cortical responses to electrical stimulation of the periodontal ligament in mice.2024

Author(s)

Organizer

Data Source

[Presentation] Activation of insular cortical projections to the parabrachial nucleus regulates pain-related behaviors in rats.2024

Author(s)

Organizer

Data Source

[Presentation] Ghrelin regulates excitatory synaptic transmission from the insular cortex to the nucleus of the solitary tract in the rat.2024

Author(s)

Organizer

Data Source

[Presentation] Regulation of nociception in orofacial area by long-term potentiation of inhibitory synapses in the insular cortex using optogenetics.2024

Author(s)

Kobayashi Satomi 小林理美