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OHYANAGI Harumasa  大柳 治正

ORCIDConnect your ORCID iD *help
Researcher Number 00030958
Other IDs
Affiliation (based on the past Project Information) *help 2003: KINKI UNIVERSITY, School of Medicine, Chief Professor, 医学部, 教授
2002: 近畿大学, 医学部附属病院, 助教授
1992 – 2001: 近畿大学, 医学部, 教授
1997: 近畿大学, 医学部
1988 – 1991: 神戸大学, 医学部, 助教授
Review Section/Research Field
Principal Investigator
Digestive surgery / General surgery
Except Principal Investigator
Digestive surgery / General surgery
Keywords
Principal Investigator
Small Molecular Weight G proteins / Pancreatic Acini / Bile Acids / Colon Carcinogenesis / ホスホリパーゼC / 大腸癌 / 大腸粘膜上皮細胞 / 単離膵腺房細胞 / 低分子量G蛋白 / GTP結合蛋白質 … More / 大腸発癌 / 胆汁酸 / GI Tract Malignancy / Pancreatic Malignancy / Hepatobiliary Malignarcy / Drug Delivery System / Topical Chemotherapy / Monoclonal Antibody / Polymer drug complex / 高分子・薬物複合体 / 肝癌治療 / drug delivery system / 癌局所化学療法 / モノクローナル抗体 / 高分子薬物複合体 … More
Except Principal Investigator
apoptosis / oxidant stress / nitric oxide / ATP / 3-aminobenzamide / ischemia reperfusion injury / 虚血再灌流障害 / オキシダントストレス / glutathione / KM01 / Caco-2 / DNA damage / poly(ADP-ribose)polymerase / DNA障害 / IGF-1 / oxidative stress / drug delivery system / 循環障害 / グルタチオン / 組織血流障害 / 臓器障害 / 虚血再灌流 / 酸素ラジカル / IL-10 / 膵島移植 / 膵癌 / Adriamycin-Dextran conjugate / Clinical antibodies / Human monoclonal antibodies / Targeting chemotherapy / Tumor markers / Monoclonal antibodies / ヒトモノクローナル抗体 / ターゲティング療法KM01 / 腫瘍マーカー / モノクメーナル抗体 / 膵癌治療 / 膵臓早期診断 / ヒト・キメラ抗体 / アドリアマイシン酸化デキストラン複合体 / ヒト、モノクロ-ナル抗体 / ヒト、ハイブリド-マ / KM_<10> / 酸化デキストラン・アドリア複合体 / キメラ化抗体 / ヒトモノクロ-ナル抗体 / KM10 / タ-ゲッティング療法 / 腫瘍マ-カ- / モノクロ-ナル抗体 / multiple organ failure / poly(ADP-ribose) polymerase / 多臓器不全 / 血再灌流障害 / TEER / Co-culture / Intraepithelial Lymphocytes / Intestinal Mucosal Immunit / Gut Associated Lymphoid Tissue / Mucosal Permeability / co-culture / CaCo-2 / 腸管免疫 / 上皮間電気抵抗 / 共培養 / 腸管上皮内リンパ球 / 腸管粘膜免疫 / 腸管関連リンパ組織 / 腸管粘膜透過性 / 3-アミノべンザマイド / ニトロタイロシン / ポリADPリボースポリメラーゼ / 活性酸素 / nitrotyrosine / peroxynitrite / poly-ADP-ribose / DNA / poly (ADP-ribose) synthase / オキシダートストレス / 一酸化窒素 / Kupffer cells / liver failure / hepatectomypostoperative / aged / Kupffer細胞 / 術後肝不全 / 肝切除 / 加齢 / hyperendotoxemia / sepsis / benzamide / poly(ADP-riboss)polymerase / オキシダンストレス / 高エンドトキシン血症 / 敗血症 / 虚血再潅流障害 / microvascular circulation / organ injury / reperfusion / ischemia / superoxide / Nitric oxide / non-heart-beating donor / A cidic oxidative potential water / gene transfection / porcine islets / Islet transplantation / vector / islet bank / 膵ラ島凍結保存法 / 分離培養法 / Immunomodulation / 睾丸 / 胸腺 / Islet bant / 凍結保存 / 膵ラ島分離培養法 / 膵ラ島 / 心臓死ドナー / 電界酸性水 / 遺伝子導入 / ブタ膵島 / Caerulein-induced pancreatitis / Small molecular GTP-pinding protein / Microtubules / Cytoskeleton / Acute pancreatitis / 膵外分泌機構 / 膵外分泌 / セルレイン誘起膵炎 / 低分子量GTP結合蛋白質 / 微小管 / 細胞骨格 / 急性膵炎 / high-dose hepatic arterial chemotherapy / direct hemoperfusion / Hepatic venous isolation / Treatment of advanced hepatic tumor / 体外循環 / アドリアマイシン / 大量動注 / 肝癌治療 / アンギオテンシンII / Double ballons technique / 大量肝動注療法 / 活性炭吸着 / 肝静脈分離 / 進行肝癌治療 / pancreas preservation / rejection / pancreatic secretory trypsin inhibitor / ATP tissue concentration / mechanism of pancreas oxygenation / two-layer cold storage method / pancreatoesophagostomy / pancreas transplantation / Rescue Therapy / 膵酸素化の機序 / 二層単純浸漬膵保存法 / 膵腎同種移植 / 免疫抑制剤 / 膵酸素化機序 / 膵同種移植 / 膵組織内ATP濃度 / 96時間膵保存 / perfluorochemical / 膵保存 / 拒絶反応 / 膵分泌性トリプシンインヒビタ-(PSTI) / 膵組織内ATP / 膵酸策化機序 / 二層単純浸漬保存法 / 膵食道吻合 / 膵移植 / 高分子-薬物複合体 Less
  • Research Projects

    (14 results)
  • Co-Researchers

    (27 People)
  •  Role of poly(ADP-ribose) polymerase activation in development of multiple organ failure in ischemia-reperfusion injury

    • Principal Investigator
      YONEKURA Takeo
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      KINKI UNIVERSITY
  •  Interaction of nitric oxide and reactive oxygen on ADP-ribose-polymerase activation DNA damage

    • Principal Investigator
      YONEKURA Takeo
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      KINKI UNIVERSITY
  •  Research on The Effect of Intraepitherial Lymphocytes on Intestinal Mucosal Permeability

    • Principal Investigator
      USUI Noriaki
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Osaka University
      Kinki University
  •  膵ラ島移植および新しい高分子-薬物複合体を応用した膵癌集学的治療

    • Principal Investigator
      HAJI Seiji
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      Kinki University
  •  Mechanism of multiple organ failure caused by interaction of nitric oxide and oxidant stress

    • Principal Investigator
      YONEKURA Takeo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      KINKI UNIVERSITY
  •  The developmental mechanism of liver failure after hepatectomy in aged and the effect of growth factor administration

    • Principal Investigator
      NOMURA Hideaki
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      KINKI UNIVERSITY SCHOOL OF MEDICINE
  •  The development of novel topical anti-cancerous chemotherapy applied with high molecular biocompetible polymer-drug complex or monoclonal antibodies.Principal Investigator

    • Principal Investigator
      OHYANAGI Harumasa
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Kinki University
  •  Nitric oxide and superoxide in ishcemia/reperfusion injury

    • Principal Investigator
      YONEKURA Takeo
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kinki University
  •  Islet Transplantation of IL-10 gene transfection into Thymus and Testis

    • Principal Investigator
      MIYAMOTO Masaaki
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Kinki University, School of Medicine
  •  MOLECULAR APROACH FOR INVESTIGATION OF ONSET MECHANISM IN ACUTE PANCREATITIS

    • Principal Investigator
      SAITOH Yoichi
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Digestive surgery
    • Research Institution
      KOBE UNIVERSITY SCHOOL OF MEDICINE
  •  A study of Intraarterial High Dose Chemotherapy Using Direct Hemoperfusion Under Hepatic Venous Isolation for Heratic Tumors

    • Principal Investigator
      GU Eisei
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kobe University
  •  Experimental Research for Pancreas Transplantation

    • Principal Investigator
      KURODA Yoshikazu
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kobe University
  •  Clinical and experimental studies on early diagnosis and improvement of therapeutic effect pancreatic cancer using monoclonal antibodies.

    • Principal Investigator
      SAITO Yoichi
    • Project Period (FY)
      1988 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Digestive surgery
    • Research Institution
      Kobe University
  •  MECHANISM OF ACTION OF BILE ACIDS AS PROMOTER FOR COLON CARCINOGENESISPrincipal Investigator

    • Principal Investigator
      OHYANAGI Harumasa
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      KOBE UNIVERSITY
  • 1.  SAITOH Yoichi (90004803)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  MIYAMOTO Masaaki (50229895)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  YONEKURA Takeo (00258021)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  KUBOTA Akio (10161671)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  HOUKI Masanori (40278685)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  YAMAMOTO Masahiro (40166822)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  KU Yonson (40195615)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  HAJI Seiji (80288935)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  KURODA Yoshikazu (70178143)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  TAKEYAMA Yoshifumi (70263374)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  KURODA Daisuke (30248041)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  NOMURA Hideaki (20248040)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  IMANO Motohiro (00278681)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  HIROOKA Shinji (10268394)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  KOSUMI Takuya (90340827)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  YAGI Makoto (20191091)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  HIGASHINO Hideaki (40122098)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  USUI Noriaki (30273626)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  USAMI Makoto (00193855)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  KAETSU Isao (00214247)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  TAKAI Yoshimi (60093514)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  野瀬 恵介 (20268395)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  加藤 道男 (30140445)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  田中 龍彦 (20179766)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  KASAHARA Hiroshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  MIYAZAKI Naoyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  石田 常之
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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