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TAKAI YOSHIMI  高井 義美

… Alternative Names

TAKAI Yoshimi  高井 義美

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Researcher Number 60093514
Other IDs
  • ORCIDhttps://orcid.org/0009-0007-0910-5297
Affiliation (Current) 2025: 神戸大学, 医学研究科, 特命教授
Affiliation (based on the past Project Information) *help 2014 – 2019: 神戸大学, 医学研究科, 特命教授
2013 – 2015: 神戸大学, 医学(系)研究科(研究院), 教授
2014: 神戸大学, 大学院医学研究科, 教授
2012: 神戸大学, 医学(系)研究科(研究院), 特命教授
2011: 神戸大学, 医学(系)研究科(研究院), 教授 … More
2008 – 2010: Kobe University, 医学研究科, 教授
2009: 神戸大学, 医学研究科
2009: Kobe University, 大学院・医学研究科, 教授
2007: 大阪大学, 大学院・医学系研究科, 教授
1999 – 2007: Graduate School of Medicine, Osaka University Professor, 医学系研究科, 教授
2005 – 2006: Osaka University, Graduate School/Faculty of Medicine, Professor, 大学院医学系研究科, 教授
1999 – 2005: 大阪大学, 大学院・医学系研究科, 教授
2001: 大阪大学, 医学研究科, 教授
1994 – 1999: 大阪大学, 医学部, 教授
1998: 大阪大学, 教授, 教授
1995: 神戸大学, 医学部, 教授
1994 – 1995: 岡崎国立共同研究機構, 生理学研究所, 教授
1994: 大阪大学, 薬学部, 教授
1994: 神戸大学, 医学部生化学, 教授
1986 – 1993: 神戸大学, 医学部, 教授
1986: Kobe University, Faculty of Medicine, Professor, 医学部, 教授
1985: 神戸大学, 医, 教授 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Pathological medical chemistry / 物質生物化学 / General medical chemistry / 代謝生物化学 / Functional biochemistry / Biological Sciences
Except Principal Investigator
Biological Sciences / Biological Sciences / Digestive surgery … More / 内分泌・代謝学 / 代謝生物化学 / General physiology / Otorhinolaryngology / 物質生物化学 Less
Keywords
Principal Investigator
Rho / GTP結合蛋白質 / Cキナーゼ / Rabphilin-3A / Rab3A / 細胞増殖因子 / Ras / 低分子量GTP結合蛋白質 / ras p21 / ホスホリパーゼC … More / 受容体 / イノシトールリン脂質 / ジグリセリド / 細胞増殖 / ネクチン / Smg GDS / Rab / がん / Rho GDI / 細胞運動 / 低分子量G蛋白質 / REKS / プロテインキナーゼ / アファディン / 細胞接着 / B-Raf / CD44 / BNI1 / smg GDS / The ERM family / small GTP-binding protein / GDP / 百日咳毒素 / 癌遺伝子 / カルシウムイオン / 細胞膜受容体 / ERM-CD44系 / MAPキナーゼ / 浸潤・転移 / rho GDI / rho p21 / ゲラニルゲラニル基 / GDI / smgp21 / GAP / Frabin / Rabphilin-11 / rabphilin-3A / 翻訳後修飾 / プレニル化 / ras遺伝子 / fos遺伝子 / シナプス / サイクリックAMP / 神経活性物質 / トランスデューサー / ホスホリパーゼ / イノシトール三リン酸 / 発癌プロモーター / ネクチン様分子 / 異種細胞間接着 / 細胞極性 / Necl-5 / 細胞外マトリックス / 細胞周期 / 細胞死 / 分化 / 14-3-3蛋白質 / アクチン細胞骨格 / GTPase活性促進蛋白質 / GDP解離促進蛋白質 / smgp25 / rasp21 / 細胞競合 / Protein Kinase C / GTP-binding Protein / Phospholipase C / Cell Surface Receptor / Phosphoinositide / Protein Kinases / Calcium Ion / Cyclic AMP / Intracellular Messengers / Nuclear Genes / Cell Surface Receptors / 細胞内伝達系 / 核遺伝子 / Small G Protein / ROCK / mDia / SPA2 / SHP-2 / RabGD1 / BNT1 / SMAP / SmgGDS / Rap1 / Small GTP-binding / Rabphi7in-3A / Doc2 / PKC1 / プロフィリン / BNR1 / 神経伝達物質 / ゲラニルゲラニル基転移酵素 / ファルネシル基転移酵素 / C末端側ペプチド / rac p21 / シナプス小胞 / 標的蛋白質 / 活性制御蛋白質 / 活性酸素 / 平滑筋 / リン酸化 / 細胞内情報伝達機構 / rabphilin / rab3A p25 / smg p25A / CDC25Mm / Tumor markers / GTPase activating protein / GTP exchange protein / prenylation / small GTP-binding proteins / <ras>___ー p21 / 腫瘍マ-カ- / GTPase活性化蛋白質 / GTP交換反応調節蛋白質 / GTPase Activating Protein / GTP Exchange Protein / Prenylation / Intracellular Messenger Systems / Small GTP-Binding Protein / smgp25A / ゲニラルゲラニル基 / クロスト-ク / GDP解離抑制蛋白質 / C-rasp21 / cyclic AMP / Ca^<2+> / 動脈硬化 / 発がんプロモーター / イノシトールリン脂質代謝 / 血管平滑筋細胞 / イノシトールリン酸 / cyclicAMP / 細胞情報伝達機構 / 細胞シグナル伝達機構 / 細胞接着・運動 / 神経シナプス / 上皮細胞 / 神経突起 / 肺腺がん / ネクチン様分子-5 / デスモソーム / アドヘレンスジャンクション / タイトジャンクション / アドへレンスジャンクション / Necl - 5 / Nec1-5 / 増殖因子受容体 / インテグリン / Necl / 接着 / 転移 / 浸潤 / 増殖 / 組織 / Frabin-Cdc42系 / Nectin-Afadin-Ponsin系 / Rab11 / Gab-1 / Frabin-Cdc42 / Nectin-Afadin / Cadherin-Catenin系 / Nectin-Afadin系 / Rac / Cdc42 / シグナル伝達 / 増殖因子 / アクチン / ERM / 細胞骨格 / 細胞内小胞輸送 / TPA感受性因子 / C3 / HGF / 'cーfos遺伝子 / rafキナ-ゼ / Aキナ-ゼ / smg p21 / Cキナ-ゼ / c-fos遺伝子 / Aキナーゼ / cーrafー1蛋白質 / cーfos … More
Except Principal Investigator
GTP結合蛋白質 / 低分子量G蛋白質 / 神経伝達物質 / Rabphilin-3A / 低分子量GTP結合蛋白質 / イオンチャネル / Rab3A / 血管平滑筋 / シグナル伝達 / Rho / がん / 心筋症 / 心筋虚血 / 癌遺伝子 / イノシトールリン酸代謝 / 心筋細胞 / ADP-ribosylation / ADPリボシル化 / 酵母 / ロイコトリエン / サイクリックAMP / 癌 / Ca^<2+> / C2様領域 / がん遺伝子 / 細胞死 / 遺伝子 / RabGDI / リゾフォスファチジルコリン / エンドセリン / シナプトタグミン / アクティブゾーン / rabphilin / 細胞内小胞輸送 / リポ蛋白 / 血管内皮由来弛緩因子 / 血管内皮 / 百日咳毒素 / 共役機構 / 細胞競合 / Small Molecular Weight G proteins / Pancreatic Acini / Bile Acids / Colon Carcinogenesis / ホスホリパーゼC / 大腸癌 / 大腸粘膜上皮細胞 / 単離膵腺房細胞 / 低分子量G蛋白 / 大腸発癌 / 胆汁酸 / Molecular Target Therapy / Gene Manipulated Animals / Cancer Genome / Support for Young Investigators / International Scientific Exchange / Screening / Research Materials / Cancer / 若手支授 / 研究資材 / 医療・福祉 / 分子標的治療 / 遺伝子操作動物 / がんゲノム / 若手支援 / 国際学術研究交流 / スクリーニング / 研究資料 / Signal transduction / Phosphorylation / Vesicle transport / Small GTP-binding protein / 情報伝達 / リン酸化 / Membrane receptor / Wortmannin / Gbetagamma subunit / Protein tyrosine kinase / PtdIns 3-kinase / Growth factor / Ras protein family / Heterotrimeric G-protein / 走化性ペプチド / 活性酸素生成 / インシュリン / ras蛋白質ファミリー / Cβγサブユニット / 細胞膜受容体 / ワ-トマニン / Gβγサブユニット / チロシンキナーゼ / PI-3-キナーゼ / 細胞増殖因子 / Ras蛋白質ファミリー / 3量体G蛋白質 / Small G Protein / 増殖因子 / HDL / 酸化LDL / VLDL容体 / VLDL受容体 / SDMF / コレステロール逆転送系 / CETP / M-CSF / マクロファージ / Secretion / Mammalian / Yeast / Botulinum toxin / GTP-binding protein / Low molecular weight / 分泌 / 哺乳類 / ボツリヌス毒素 / GTP結分蛋白質 / 低分子量 / pancreatic acinar cells / chromaffin cells / membrane capacitance / GDP-dissociation stimulator / GDP-dissociation inhibitor / Small molecular GTP-binding protein / アラキドン酸 / 膵外分泌腺細胞 / 膵腺房細胞 / G蛋白 / カルシウム濃度 / 巨核球 / ルテニウムレッド / イノシト-ル三リン酸 / furaー2 / VIP / GDP解離促進因子 / 膜容量変化 / GDP解離抑制因子 / 低分子量GTP結合蛋白 / カルシウム依存性プロテーゼ / カルモジュリン遺伝子 / リポコルチン / カルデスモン / ゲルゾリン / カルシウム依存性ブロテアーゼ / Ca調節 / カルパクチン / ゲルゾリンファミリー / ラッチ機構 / キャッチ機構 / 平滑筋ミオシン / サイクリックGMP / リポソーム / 味細胞 / 嗅細胞 / 視細胞 / ムスカリン受容体 / 再生 / 嗅球 / nectin / BDNF / IGF / bFGF / NGF / 嗅神経細胞 / 細胞接着因子 / 神経栄養因子 / 嗅上皮 / 嗅神経 / ウィルス / 細胞組織 / 細胞・組織 / ゲノム / ウイルス / 遺伝学 / 発がん制御 / RIFファミリー / 発がん抑制 / 樹状細胞 / p53 / IRFファミリー / インターフェロン / 研究支援・広報 / がん治療 / がん診断・予防 / がん特性 / 発がん / がん研究支援 / がん研究の連携 / がん科学のニューフロンティア / 個人に最適ながん治療 / がんの体系的理解 / 成果取り纏め / Ca^<2+>センサー / 機能領域 / アンカリング蛋白質 / シナプス小胞 / Doc2 / がん研究の推進 / 薬剤耐性 / 白血病 / 腫瘍血管 / 細胞接着 / 先端的研究 / アポトーシス / アボトーシス / 細胞生物学 / がん細胞 / ヒトがん / がん転移 / 細胞分化 / 細胞増殖 / 細胞間相互作用 / 転移 / 分化 / 増殖 / アクチンフィラメント / CD44 / ERMファミリー / 収縮環 / 細胞質分裂 / BNP / ANP / 心肥大 / 心不全 / アドレノメデュリン / アンジオテンシンII / 細胞内情報伝達 / G protein / Angiotensin II / endothelin / adrenomedulin / calcium ion / signal transduction / mechanical stress / cardiomyocytes / カルモデュリンキナーゼII / シナプス / トランスロケーション / Ca^<2+>チャネル / ral3A p25 / smg p25a / リポ蛋白リパーゼ / エンドセリンファミリー / ナトリウム利尿ペプチドファミリー / 胎児型ミオシン重鎖 / PD-ECGF / アクチビンA / NO / CNP / regulated secretion / rab3A p25 / smp p25A / バイオサイエンス / リポ蛋白リパ-ゼ / エンドセリンファミリ- / ナトリウム利尿ペプチドファミリ- / NDPキナ-ゼ / 受容性 / トランスメンブランコントロ-ル / NDPキナーゼ / 受容体 / トランスメンブランコントロール / カルシウム依存性プロテアーゼ / 分子薬理学 / 阻害剤 / プロテインキナーゼ / 蛋白質リン酸化反応 Less
  • Research Projects

    (70 results)
  • Research Products

    (171 results)
  • Co-Researchers

    (139 People)
  •  Roles and modes of action of nectins in heterotypic cell-cell adhesionsPrincipal Investigator

    • Principal Investigator
      Takai Yoshimi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      Kobe University
  •  Cell competition: a mechanism for survival of the fittest in the multi-cellular community

    • Principal Investigator
      Fujita Yasuyuki
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  Elucidation of roles and modes of action of cell adhesion molecules involved in epithelial cell competitionPrincipal Investigator

    • Principal Investigator
      Takai Yoshimi
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  Comprehensive Study on Regeneration of Olfactory Epithelium and Bulb

    • Principal Investigator
      KEN-ICH Nibu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Kobe University
  •  Roles of Cell Adhesion and Signaling in Cell MorphogenesisPrincipal Investigator

    • Principal Investigator
      TAKAI YOSHIMI
    • Project Period (FY)
      2009 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Functional biochemistry
    • Research Institution
      Kobe University
  •  Role of cell adhesion signaling in the abnormal cell polarization of cancer cellsPrincipal Investigator

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
      Osaka University
  •  Integrative Research Toward the Conquest of Cancer

    • Principal Investigator
      TANIGUCHI Tadatsgu
    • Project Period (FY)
      2004 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Genetic and Epigenetic Dysregulation in Cancer

    • Principal Investigator
      NODA Tetsuo
    • Project Period (FY)
      2004 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Japanese Foundation For Cancer Research
      Tohoku University
  •  Disorganization of cell and tissue systems in cancerPrincipal Investigator

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      2004 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
      Osaka University
  •  細胞増殖のシグナリング機構Principal Investigator

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  がんの生物学的特性の研究の総括

    • Principal Investigator
      SASAZUKI Takehiko, 黒木 登志夫
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyushu University
      Showa University
      The University of Tokyo
  •  がんの戦略的先端研究

    • Principal Investigator
      渋谷 正史, 吉田 光昭
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  がんの生物学的特性に関する研究の総括Principal Investigator

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1999 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  General Promotion of Cancer Research in Japan

    • Principal Investigator
      TSURUO Tahashi
    • Project Period (FY)
      1999 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tokyo
  •  Modes of activation and action of Small G proteinsPrincipal Investigator

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General medical chemistry
    • Research Institution
      Osaka University
  •  C_2様領域を持つ新しい蛋白質Rabphilin-3AとDoc2の機能と作用機構

    • Principal Investigator
      佐々木 卓也
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  シナプスにおける新しいCa^<2+>センサーの機能と作用機構

    • Principal Investigator
      白瀧 博通
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okazaki National Research Institutes
  •  神経伝達物質の放出機構におけるRab3A低分子量G蛋白質系の機能と作用機構

    • Principal Investigator
      佐々木 卓也
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  プレ・ポストシナプスの相互作用における低分子量G蛋白質の役割と作用機構

    • Principal Investigator
      SHIRATAKI Hiromichi
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okazaki National Research Institutes
  •  心筋細胞の刺激受容機構とシグナル伝達系

    • Principal Investigator
      矢崎 義雄
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  細胞質分裂における低分子量G蛋白質Rhoの機能と作用機構

    • Principal Investigator
      佐々木 卓也
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  細胞の増殖・分化のシグナルの伝達機構Principal Investigator

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1994 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  Signal transduction of Small GTP-binding proteinsPrincipal Investigator

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Osaka University
  •  cDNAs and antibodies for small GTP-binding proteinsPrincipal Investigator

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
  •  細胞内情報伝達系と細胞増殖の制御機構Principal Investigator

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kobe University
  •  血管機能における神経・体液性因子の相関・病態

    • Principal Investigator
      北 徹
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  蛋白質の選別輸送における低分子量GTP結合蛋白質の機能と作用機構

    • Principal Investigator
      佐々木 卓也
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kobe University
  •  GTP-binding Proteins as Cellular Signal Transducer

    • Principal Investigator
      UI Michio
    • Project Period (FY)
      1993 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
      The Institute of Physical and Chemical Research
  •  Action mechanisms and roles of small GTP-binding proteins

    • Principal Investigator
      NOZAWA Yoshinori
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Gifu University
  •  蛋白質の選別輸送における低分子量GTP結合蛋白質の機能と作用機構

    • Principal Investigator
      佐々木 卓也
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kobe University
  •  神経伝達物質放出における低分子量GTP結合蛋白質の機能と作用機構

    • Principal Investigator
      貝淵 弘三
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kobe University
  •  情報転換因子としてのGTP結合蛋白質

    • Principal Investigator
      UI Michio
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Institution
      The University of Tokyo
  •  動脈硬化症の分子生物学的解析と予防・抑制対策に関する総合的研究

    • Principal Investigator
      北 徹
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Kyoto University
  •  細胞内情報伝達系と細胞増殖の制御機構Principal Investigator

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kobe University
  •  血管機能における神経・体液性因子の相関・病態

    • Principal Investigator
      井村 裕夫
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Studies on the conformation and functions of ras-related low Mr GTP-binding proteins.

    • Principal Investigator
      NOZAWA Yoshinori
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      代謝生物化学
    • Research Institution
      Gifu University
  •  signal transduction of small GTP binding proteinsPrincipal Investigator

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kode University
  •  cDNAs and antibodies for small GTP-binding proteinsPrincipal Investigator

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      代謝生物化学
    • Research Institution
      Kobe University
  •  トランスメンブランコントロ-ルにおけるGTP結合蛋白質の役割

    • Principal Investigator
      野村 靖幸
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  バイオサイエンスの進展に基づくがんの重点研究

    • Principal Investigator
      豊島 久真男
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  細胞内情報伝達系と細胞増殖の制御機構Principal Investigator

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kobe University
  •  バイオサイエンスの進展に基づくがんの重点研究

    • Principal Investigator
      豊島 久真男
    • Project Period (FY)
      1990 – 1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  バイオサイエンスの進展に基づくがんの重点研究

    • Principal Investigator
      豊島 久真男
    • Project Period (FY)
      1990 – 1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  細胞増殖シグナル伝達の機構と癌遺伝子産物の作用Principal Investigator

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  蛋白質リン酸化反応の生物学的意義に関する総合的研究

    • Principal Investigator
      日高 弘義
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      Nagoya University
  •  心筋細胞の損傷・修復過程とその修飾因子

    • Principal Investigator
      河合 忠一
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  トランスメンブランコントロールにおけるGTP結合蛋白質の役割

    • Principal Investigator
      野村 靖幸
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  細胞分化の制御におけるCキナ-ゼとrasp21類似GTP結合蛋白質の作用機構Principal Investigator

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kobe University
  •  Physiological roles of low molecular weight 20KG GTP-binding protein : Effects on secretion in pancreatic acinar cells.

    • Principal Investigator
      MARUYAMA Yoshio
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      Jichi Medical School
  •  Small GTP-Binding Proteins and Intracellular Messenger SystemsPrincipal Investigator

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      代謝生物化学
    • Research Institution
      Kobe University
  •  cDNAs and Antibodies for Small GTP-binding ProteinsPrincipal Investigator

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B).
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kobe University
  •  細胞の癌化におけるCキナーゼと癌遺伝子の相互作用Principal Investigator

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  細胞増殖因子による細胞周期の制御機構におけるCキナーゼの役割Principal Investigator

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kobe University
  •  心筋細胞の損傷・修復過程とその修飾因子

    • Principal Investigator
      河合 忠一
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  MECHANISM OF ACTION OF BILE ACIDS AS PROMOTER FOR COLON CARCINOGENESIS

    • Principal Investigator
      OHYANAGI Harumasa
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      KOBE UNIVERSITY
  •  細胞の癌化におけるCキナーゼと癌遺伝子の相互作用Principal Investigator

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  シナプスの可塑性におけるCキナーゼの役割Principal Investigator

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Kobe University
  •  神経伝達物質によるイノシトールリン脂質代謝の抑制機構Principal Investigator

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kobe University
  •  心筋細胞の損傷・修復過程とその修飾因子

    • Principal Investigator
      河合 忠一
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Phosphoinositide metabolism in transmembrane signallingPrincipal Investigator

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      Kobe University
  •  細胞の癌化におけるCキナーゼと癌遺伝子の相互作用Principal Investigator

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  受容分子からイオンチャネルへの情報伝達

    • Principal Investigator
      栗原 堅三
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Hokkaido University
  •  神経活性物質受容体によるジグリセリド産生の制御機構Principal Investigator

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Kobe University
  •  血管平滑筋細胞の細胞膜受容伝達機構を構成する蛋白質の同定とその機能の解析Principal Investigator

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Kobe University
  •  血管平滑筋収縮蛋白の制御

    • Principal Investigator
      野々村 禎昭
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      The University of Tokyo
  •  血管平滑筋収縮蛋白の制御

    • Principal Investigator
      野々村 禎昭
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      The University of Tokyo
  •  Cキナーゼとカルシウムによる細胞増殖の制御機構Principal Investigator

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  細胞膜リン脂質の動的代謝による新しいカルシウムイオンの動員機構Principal Investigator

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Kobe University
  •  神経活性物質受容体によるジグリセリド産生の制御機構Principal Investigator

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Kobe University
  •  Mechanisms of signaling from cell surface receptors to nuclear genes.Principal Investigator

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      Kobe University

All 2020 2019 2018 2017 2016 2015 2014 2013 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

  • [Book] The Sticky Synapse: Cell Adhesion Molecules and Their Role in Synapse Formation and Maintenance.2009

    • Author(s)
      T ogashi H, Ogita H, Takai Y.
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-16060101
  • [Book] A cell-free assay for endocytosis of E-cadherin.(In Methods in Molecular Biology)(Vol.440)2007

    • Author(s)
      Sakisaka T, Takai Y.
    • Publisher
      Humana Press, Totowa
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Book] Activation of Rap1, Cdc42, and Rac by nectin adhesion system.(In Methods Enzymol)(Vol.406)2006

    • Author(s)
      Ogita H, Takai Y.
    • Publisher
      Academic Press, San Diego
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Book] Nectins and nectin- like molecules : Roles in cell adhesion, polarization, movement, and proliferation.(In IUBMB Life)(Vol.58)2006

    • Author(s)
      Ogita H, Takai, Y.
    • Publisher
      Taylor & Francis, Oxford
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Book] Molecular perspective on tight-junction assembly and epithelial polarity.(In Advanced Drug Delivery Rev)(Vol.57)2005

    • Author(s)
      Miyoshi J, Takai Y.
    • Publisher
      Elsevier Science, Amsterdam
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Book] Purification and properties of Rabconnectin-3.(In Methods Enzymol)(Vol.403)2005

    • Author(s)
      Sakisaka T, Takai, Y.
    • Publisher
      Academic Press, San Diego
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Book] Purification and properties of Rab3 GEP (DENN/MADD).(In Methods Enzymol)(Vol.403)2005

    • Author(s)
      Sakisaka T, Takai, Y.
    • Publisher
      Academic Press, San Diego
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Afadin regulates actomyosin organization through αE-catenin at adherens junctions.2020

    • Author(s)
      Sakakibara S, Mizutani K, Sugiura A, Sakane A, Sasaki T, Yonemura S, Takai Y.
    • Journal Title

      J Cell Biol.

      Volume: 219 Issue: 5

    • DOI

      10.1083/jcb.201907079

    • NAID

      120007132269

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08636, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-20K15793, KAKENHI-PROJECT-18H02617
  • [Journal Article] Interaction of nectin-2α with the auxiliary protein of the voltage-gated A-type K(+) channel Kv4.2 dipeptidyl aminopeptidase-like protein at the boundary between the adjacent somata of clustered cholinergic neurons in the medial habenula2019

    • Author(s)
      Shiotani H, Miyata M, Mizutani K, Wang S, Mizoguchi A, Mochizuki H, *Mandai K, *Takai Y
    • Journal Title

      Mol. Cell. Neurosci.

      Volume: 94 Pages: 32-40

    • DOI

      10.1016/j.mcn.2018.11.001

    • NAID

      120006850502

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-16H06463, KAKENHI-PUBLICLY-17H05700, KAKENHI-PLANNED-26114007
  • [Journal Article] Nectin-4 cis-interacts with ErbB2 and its trastuzumab-resistant splice variants, enhancing their activation and DNA synthesis2019

    • Author(s)
      Kedashiro Shin、Sugiura Ayumu、Mizutani Kiyohito、Takai Yoshimi
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1

    • DOI

      10.1038/s41598-019-55460-9

    • NAID

      120006777088

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16744, KAKENHI-PLANNED-26114007
  • [Journal Article] Roles of the third Ig-like domain of Necl-5/PVR and the fifth Ig-like domain of the PDGF receptor in its signaling2018

    • Author(s)
      Ueda Yuki、Kedashiro Shin、Maruoka Masahiro、Mizutani Kiyohito、Takai Yoshimi
    • Journal Title

      Genes to Cells

      Volume: 23 Issue: 3 Pages: 214-224

    • DOI

      10.1111/gtc.12564

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K15597, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-16K19035
  • [Journal Article] Localization of nectin-2α at the boundary between the adjacent somata of the clustered cholinergic neurons and its regulatory role in the subcellular localization of the voltage-gated A-type K+ channel Kv4.2 in the medial habenula2018

    • Author(s)
      Shiotani Hajime、Miyata Muneaki、Itoh Yu、Wang Shujie、Kaito Aika、Mizoguchi Akira、Yamasaki Miwako、Watanabe Masahiko、Mandai Kenji、Mochizuki Hideki、Takai Yoshimi
    • Journal Title

      J Comp Neurol.

      Volume: 526 Issue: 9 Pages: 1527-1549

    • DOI

      10.1002/cne.24425

    • NAID

      120006892079

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08503, KAKENHI-PLANNED-26114007, KAKENHI-PLANNED-16H06463
  • [Journal Article] Requirement of the F-actin-binding activity of l-afadin for enhancing the formation of adherens and tight junctions2018

    • Author(s)
      Sakakibara Shotaro、Maruo Tomohiko、Miyata Muneaki、Mizutani Kiyohito、Takai Yoshimi
    • Journal Title

      Genes to Cells

      Volume: 23 Issue: 3 Pages: 185-199

    • DOI

      10.1111/gtc.12566

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-16J06236, KAKENHI-PROJECT-16K19036
  • [Journal Article] Involvement of l-afadin, but not s-afadin, in the formation of puncta adherentia junctions of hippocampal synapses.2018

    • Author(s)
      Maruo T, Sakakibara S, Miyata M, Itoh Y, Kurita S, Mandai K, Sasaki T, *Takai Y
    • Journal Title

      Mol. Cell. Neurosci.

      Volume: 92 Pages: 40-49

    • DOI

      10.1016/j.mcn.2018.06.006

    • NAID

      120006850501

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-16H06463, KAKENHI-PLANNED-26114007
  • [Journal Article] Nectin-4 co-stimulates the prolactin receptor by interacting with SOCS1 and inhibiting its activity on the JAK2-STAT5a signaling pathway.2017

    • Author(s)
      Maruoka, M., Kedashiro, S., Ueda, Y., Mizutani, K., and Takai, Y.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 292 Issue: 17 Pages: 6895-6909

    • DOI

      10.1074/jbc.m116.769091

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-16K19035
  • [Journal Article] Aging-dependent expression of synapse-related proteins in the mouse brain.2017

    • Author(s)
      Shiotani, H., Maruo, T., Sakakibara, S., Miyata, M., Mandai, K., Mochizuki, H., Takai, Y.
    • Journal Title

      Genes to Cells

      Volume: 印刷中 Issue: 5 Pages: 472-484

    • DOI

      10.1111/gtc.12489

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-16K19036, KAKENHI-PROJECT-16J06236, KAKENHI-PLANNED-16H06463
  • [Journal Article] Roles of afadin in the formation of the cellular architecture of the mouse hippocampus and dentate gyrus.2017

    • Author(s)
      Miyata M, Maruo T, Kaito A, Wang S, Yamamoto H, Fujiwara T, Mizoguchi A, Mandai K, Takai Y
    • Journal Title

      Mol Cell Neurosci

      Volume: 79 Pages: 34-44

    • DOI

      10.1016/j.mcn.2016.12.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-16H06463, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-16K19036
  • [Journal Article] Multiple Roles of Afadin in the Ultrastructural Morphogenesis of Mouse Hippocampal Mossy Fiber Synapses.2017

    • Author(s)
      Sai K, Wang S, Kaito A, Fujiwara T, Maruo T, Itoh Y, Miyata M, Sakakibara S, Miyazaki N, Murata K, Yamaguchi Y, Haruta T, Nishioka H, Motojima Y, Komura M, Kimura K, Mandai K, Takai Y, Mizoguchi A.
    • Journal Title

      J Comp Neurol

      Volume: - Issue: 12 Pages: 2719-2734

    • DOI

      10.1002/cne.24238

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-16H06463, KAKENHI-PROJECT-16K01514, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-16J06236, KAKENHI-PROJECT-16K19036
  • [Journal Article] NGL-3-induced presynaptic differentiation of hippocampal neurons in an afadin-dependent, nectin-1-independent manner2017

    • Author(s)
      Maruo Tomohiko、Mandai Kenji、Miyata Muneaki、Sakakibara Shotaro、Wang Shujie、Sai Kousyoku、Itoh Yu、Kaito Aika、Fujiwara Takeshi、Mizoguchi Akira、Takai Yoshimi
    • Journal Title

      Genes to Cells

      Volume: 22 Issue: 8 Pages: 742-755

    • DOI

      10.1111/gtc.12510

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-16J06236, KAKENHI-PROJECT-16K19036, KAKENHI-PLANNED-16H06463
  • [Journal Article] Roles of afadin in functional differentiations of hippocampal mossy fiber synapse2017

    • Author(s)
      Geng Xiaoqi、Maruo Tomohiko、Mandai Kenji、Supriyanto Irwan、Miyata Muneaki、Sakakibara Shotaro、Mizoguchi Akira、Takai Yoshimi、Mori Masahiro
    • Journal Title

      Genes to Cells

      Volume: 22 Issue: 8 Pages: 715-722

    • DOI

      10.1111/gtc.12508

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-16J06236, KAKENHI-PROJECT-16K19036, KAKENHI-PLANNED-16H06463
  • [Journal Article] Multiple roles of afadin in the ultrastructural morphogenesis of mouse hippocampal mossy fiber synapses.2017

    • Author(s)
      Sai, K., Wang, S., Kaito, A., Fujiwara, T., Maruo, T., Itoh, Y., Miyata, M., Sakakibara, S., Miyazaki, N., Murata, K., Yamaguchi, Y., Haruta, T., Nishioka, H., Motojima, Y., Komura, M., Kimura, K., Mandai, K., Takai, Y., and Mizoguchi, A.
    • Journal Title

      J Comp Neurol

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Journal Article] Nectin-like molecule-4/cell adhesion molecule 4 inhibits the ligand-induced dimerization of ErbB3 with ErbB22017

    • Author(s)
      Mizutani Kiyohito、Kedashiro Shin、Maruoka Masahiro、Ueda Yuki、Takai Yoshimi
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 11375-11375

    • DOI

      10.1038/s41598-017-10107-5

    • NAID

      120006373795

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15597, KAKENHI-ORGANIZER-26114001, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-16K19035
  • [Journal Article] Synergistic action of nectins and cadherins generates the mosaic cellular pattern of the olfactory epithelium.2016

    • Author(s)
      Sayaka Katsunuma, Hisao Honda, Tomoyasu Shinoda, Yukitaka Ishimoto, Takaki Miyata, Hiroshi Kiyonari, Takaya Abe, Ken-ichi Nibu, Yoshimi Takai, and Hideru Togashi.
    • Journal Title

      The Journal of Cell Biology

      Volume: 212 Issue: 5 Pages: 561-75

    • DOI

      10.1083/jcb.201509020

    • NAID

      120005766825

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10782, KAKENHI-PROJECT-25440117, KAKENHI-PROJECT-26540158, KAKENHI-PROJECT-15K18953, KAKENHI-PLANNED-22111006, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-25440107, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-26400205
  • [Journal Article] Activity-dependent alteration of the morphology of a hippocampal giant synapse.2016

    • Author(s)
      Maruo, T., Mandai, K., Takai, Y., and Mori, M.
    • Journal Title

      Mol Cell Neurosci

      Volume: 71 Pages: 25-33

    • DOI

      10.1016/j.mcn.2015.12.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Journal Article] A Novel Nectin-mediated Cell Adhesion Apparatus Which Is Implicated in Prolactin Receptor Signaling for Mammary Gland Development2016

    • Author(s)
      Kitayama M, Mizutani K, Maruoka M, Mandai K, Sakakibara S, Ueda Y, Komori T, Shimono Y, Takai Y
    • Journal Title

      Journal of Biological Chemistry

      Volume: 291 Issue: 11 Pages: 5817-5831

    • DOI

      10.1074/jbc.m115.685917

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K14381, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-16K19035, KAKENHI-PROJECT-16K20411, KAKENHI-PROJECT-26860190
  • [Journal Article] Localization of nectin-2δ at perivascular astrocytic endfoot processes and degeneration of astrocytes and neurons in nectin-2 knockout mouse brain.2016

    • Author(s)
      Miyata M, Mandai K, Maruo T, Sato J, Shiotani H, Kaito A, Itoh Y, Wang S, Fujiwara T, Mizoguchi A, Takai Y, Rikitake Y
    • Journal Title

      Brain Res

      Volume: 1649 Pages: 90-101

    • DOI

      10.1016/j.brainres.2016.08.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-16H06463, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-16K19036
  • [Journal Article] The active zone protein CAST regulates synaptic vesicle recycling and quantal size in the mouse hippocampus.2016

    • Author(s)
      Kobayashi S, Hida Y, Ishizaki H, Inoue E, Tanaka-Okamoto M, Yamasaki M, Miyazaki T, Masahiro F, Kitajima I, Takai Y, Watanabe M, Ohtsuka T, Manabe T
    • Journal Title

      Eur J Neurosci.

      Volume: 44 Issue: 5 Pages: 2272-2284

    • DOI

      10.1111/ejn.13331

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24220007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-15H04272, KAKENHI-PROJECT-26460250, KAKENHI-PROJECT-26460251, KAKENHI-PROJECT-15K14309, KAKENHI-PROJECT-15K08612
  • [Journal Article] Nectin spot: a novel type of nectin-mediated cell adhesion apparatus.2016

    • Author(s)
      Mizutani, K., and Takai, Y.
    • Journal Title

      Biochemical Journal

      Volume: 473 Issue: 18 Pages: 2691-2715

    • DOI

      10.1042/bcj20160235

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013
  • [Journal Article] Regulatory role of the cell adhesion molecule nectin-1 in GABAergic inhibitory synaptic transmission in the CA3 region of mouse hippocampus.2016

    • Author(s)
      Geng, X., Mandai, K., Maruo, T., Wang, S., Fujiwara, T., Mizoguchi, A., Takai, Y., and Mori, M.
    • Journal Title

      Genes Cells

      Volume: 21 Issue: 1 Pages: 88-98

    • DOI

      10.1111/gtc.12322

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Journal Article] Nectin-1 spots regulate the branching of olfactory mitral cell dendrites.2015

    • Author(s)
      Fujiwara, T., Inoue, T., Maruo, T., Rikitake, Y., Ieki, N., Mandai, K., Kimura, K., Kayahara, T., Wang, S., Itoh, Y., Sai, K., Mori, M., Mori, K., Takai, Y., and Mizoguchi, A.
    • Journal Title

      Mol Cell Neurosci

      Volume: 68 Pages: 143-150

    • DOI

      10.1016/j.mcn.2015.07.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Journal Article] Nectin-1 spots as a novel adhesion apparatus that tethers mitral cell lateral dendrites in a dendritic meshwork structure of the developing mouse olfactory bulb.2015

    • Author(s)
      Inoue, T., Fujiwara, T., Rikitake, Y., Maruo, T., Mandai, K., Kimura, K, Kayahara, T, Wang, S., Itoh, Y., Sai, K., Mori, M., Mori, K., Mizoguchi, A., and Takai, Y.
    • Journal Title

      J Comp Neurol

      Volume: 523 Issue: 12 Pages: 1824-1839

    • DOI

      10.1002/cne.23762

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Journal Article] Quantitative analysis of the cellular composition in seminiferous tubules in normal and genetically modified infertile mice.2015

    • Author(s)
      Nakata H, Wakayama T, Takai Y, Iseki S.
    • Journal Title

      J Histochem Cytochem.

      Volume: 63 Issue: 2 Pages: 99-113

    • DOI

      10.1369/0022155414562045

    • NAID

      120005593935

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-25460241
  • [Journal Article] Human T-cell leukemia virus type 1 (HTLV-1) tax requires CADM1/TSLC1 for inactivation of the NF-κB inhibitor A20 and constitutive NF-κB signaling.2015

    • Author(s)
      Pujari R, Hunte R, Thomas R, van der Weyden L, Rauch D, Ratner L, Nyborg JK, Ramos JC, Takai Y, Shembade N.
    • Journal Title

      PLoS Pathog.

      Volume: 16 Issue: 3 Pages: e1004721-e1004721

    • DOI

      10.1371/journal.ppat.1004721

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013
  • [Journal Article] Crystal structure of afadin PDZ domain-nectin-3 complex shows the structural plasticity of the ligand-binding site.2015

    • Author(s)
      Fujiwara Y, Goda N, Tamashiro T, Narita H, Satomura K, Tenno T, Nakagawa A, Oda M, Suzuki M, Sakisaka T, Takai Y, Hiroaki H.
    • Journal Title

      Protein Sci.

      Volume: 24 Issue: 3 Pages: 376-385

    • DOI

      10.1002/pro.2628

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-25293071, KAKENHI-PLANNED-26114007, KAKENHI-PUBLICLY-26117513, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-26440028, KAKENHI-PROJECT-15H04337
  • [Journal Article] Impairment of radial glial scaffold-dependent neuronal migration and formation of double cortex by genetic ablation of afadin.2015

    • Author(s)
      Yamamoto H, Mandai K, Konno D, Maruo T, Matsuzaki F, Takai Y
    • Journal Title

      Brain Res

      Volume: 43 Pages: 775-86

    • DOI

      10.1016/j.brainres.2015.05.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K06727, KAKENHI-PLANNED-24113006, KAKENHI-PROJECT-26251013
  • [Journal Article] The cell adhesion molecule necl-4/cadm4 serves as a nobel regulator for contact inhibition of cell movement and proliferation.2015

    • Author(s)
      Yamana S, Tokiyama A, Mizutani K, Hirata K, Takai Y, Rikitake Y.
    • Journal Title

      PloS One.

      Volume: 10 Issue: 4 Pages: e0124259-e0124259

    • DOI

      10.1371/journal.pone.0124259

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-24790284, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-26860190, KAKENHI-PROJECT-25461128
  • [Journal Article] Nectin-1 spots as a novel adhesion apparatus that tethers mitral cell lateral dendrites in a dendritic meshwork structure of the developing mouse olfactory bulb.2015

    • Author(s)
      Inoue T, Fujiwara T, Rikitake Y, Maruo T, Mandai K, Kimura K, Kayahara T, Wang S, Ioth Y, Sai K, Mori M, Mori K, Mizoguchi A, Takai Y.
    • Journal Title

      J Comp Neurol.

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Journal Article] Nectins and nectin-like molecules in development and disease.2015

    • Author(s)
      Mandai K, Rikitake Y, Mori M, Takai Y.
    • Journal Title

      Curr Top Dev Biol.

      Volume: 112 Pages: 197-231

    • DOI

      10.1016/bs.ctdb.2014.11.019

    • ISBN
      9780124077584
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-24590354, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013
  • [Journal Article] Nectin-1 spots as a novel adhesion apparatus that tethers mitral cell lateral dendrites in a dendritic meshwork structure of the developing mouse olfactory bulb.2015

    • Author(s)
      Inoue T, Fujiwara T, Rikitake Y, Maruo T, Mandai K, Kimura K, Kayahara T, Wang S, Ioth Y, Sai K, Mori M, Mori K, Mizoguchi A, Takai Y.
    • Journal Title

      J Comp Neurol.

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26114007
  • [Journal Article] Downregulation of CXCR4 in Metastasized Breast Cancer Cells and Implication in Their Dormancy2015

    • Author(s)
      Nobutani K, Shimono Y, Mizutani K, Ueda Y, Suzuki T, Kitayama M, Minami A, Momose K, Miyawaki K, Akashi K, Azuma T, Takai Y
    • Journal Title

      PLoS One

      Volume: 10 Issue: 6 Pages: e0130032-e0130032

    • DOI

      10.1371/journal.pone.0130032

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14381, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-26860190
  • [Journal Article] Nectin-1 spots as a novel adhesion apparatus that tethers mitral cell lateral dendrites in a dendritic meshwork structure of the developing mouse olfactory bulb.2015

    • Author(s)
      Inoue T, Fujiwara T, Rikitake Y, Maruo T, Mandai K, Kimura K, Kayahara T, Wang S, Ioth Y, Sai K, Mori M, Mori K, Mizoguchi A, Takai Y.
    • Journal Title

      J Comp Neurol.

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005
  • [Journal Article] Genetic ablation of afadin causes mislocalization and deformation of Paneth cells in the mouse small intestinal epithelium.2014

    • Author(s)
      Tanaka-Okamoto M, Itoh Y, Miyoshi J, Mizoguchi A, Mizutani K, Takai Y, Inoue M.
    • Journal Title

      PLoS One.

      Volume: 9 Issue: 10 Pages: e110549-e110549

    • DOI

      10.1371/journal.pone.0110549

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-24790284, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-26860190
  • [Journal Article] Afadin regulates puncta adherentia junction formation and presynaptic differentiation in hippocampal neurons.2014

    • Author(s)
      Toyoshima D, Mandai K, Maruo T, Supriyanto I, Togashi H, Inoue T, Mori M, Takai Y.
    • Journal Title

      PLoS One.

      Volume: 9 Issue: 2 Pages: e89763-e89763

    • DOI

      10.1371/journal.pone.0089763

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-21500372, KAKENHI-PROJECT-24590354, KAKENHI-PUBLICLY-25111716, KAKENHI-PUBLICLY-25127710, KAKENHI-PROJECT-25440107, KAKENHI-PROJECT-25860214, KAKENHI-PROJECT-26400205
  • [Journal Article] Absence of primary cilia in cell cycle-arrested human breast cancer cells.2014

    • Author(s)
      Nobutani K, Shimono Y, Yoshida M, Mizutani K, Minami A, Kono S, Mukohara T, Yamasaki T, Itoh T, Takao S, Minami H, Azuma T, Takai Y.
    • Journal Title

      Genes Cells.

      Volume: 19 Issue: 2 Pages: 141-152

    • DOI

      10.1111/gtc.12122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-23501268, KAKENHI-PROJECT-24790284, KAKENHI-PUBLICLY-25130707
  • [Journal Article] Syntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion.2014

    • Author(s)
      Zhu Q, Yamakuchi M, Ture S, de la Luz Garcia-Hernandez M, Ko KA, Modjeski KL, LoMonaco MB, Johnson AD, O'Donnell CJ, Takai Y, Morrell CN, Lowenstein CJ.
    • Journal Title

      J Clin Invest.

      Volume: 124 Issue: 10 Pages: 4503-4516

    • DOI

      10.1172/jci71245

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-26293130
  • [Journal Article] Afadin requirement for cytokine expressions in keratinocytes during chemically induced inflammation in mice.2014

    • Author(s)
      Yoshida T, Iwata T, Takai Y, Birchmeier W, Yamato M, Okano T.
    • Journal Title

      Genes Cells.

      Volume: 19 Issue: 11 Pages: 842-852

    • DOI

      10.1111/gtc.12184

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013
  • [Journal Article] Aberrant cochlear hair cell attachments caused by Nectin-3 deficiency result in hair bundle abnormalities.2014

    • Author(s)
      Fukuda T, Kominami K, Wang S, Togashi H, Hirata K, Mizoguchi A, Rikitake Y, Takai Y.
    • Journal Title

      Development.

      Volume: 141 Issue: 2 Pages: 399-409

    • DOI

      10.1242/dev.094995

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-23300284, KAKENHI-PUBLICLY-25111716, KAKENHI-PUBLICLY-25127710, KAKENHI-PROJECT-25440107, KAKENHI-PROJECT-26400205
  • [Journal Article] Suppression of the TGF-β1-induced protein expression of SNAI1 and N-cadherin by miR-199a.2014

    • Author(s)
      Suzuki T, Mizutani K, Minami A, Nobutani K, Kurita S, Nagino M, Shimono Y, Takai Y.
    • Journal Title

      Genes Cells.

      Volume: 19 Issue: 9 Pages: 667-675

    • DOI

      10.1111/gtc.12166

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-23501268, KAKENHI-PROJECT-24790283, KAKENHI-PROJECT-24790284, KAKENHI-PUBLICLY-25130707, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013, KAKENHI-PROJECT-26860190
  • [Journal Article] Platelet secretion and hemostasis require syntaxin-binding protein STXBP5.2014

    • Author(s)
      Ye S, Huang Y, Joshi S, Zhang J, Yang F, Zhang G, Smyth SS, Li Z, Takai Y, Whiteheart SW.
    • Journal Title

      J Clin Invest.

      Volume: 124 Issue: 10 Pages: 4517-4528

    • DOI

      10.1172/jci75572

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013
  • [Journal Article] s-Afadin binds more preferentially to the cell adhesion molecules nectins than l-afadin.2014

    • Author(s)
      Kobayashi R, Kurita S, Miyata M, Maruo T, Mandai K, Rikitake Y, Takai Y.
    • Journal Title

      Genes Cells.

      Volume: 19 Issue: 12 Pages: 853-863

    • DOI

      10.1111/gtc.12185

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-24590354, KAKENHI-PROJECT-24790283, KAKENHI-PROJECT-25860214, KAKENHI-PLANNED-26114007, KAKENHI-PROJECT-26251013
  • [Journal Article] Association analysis of the DISC1 gene with schizophrenia in the Japanese population and DISC1 immunoreactivity in the postmortem brain.2013

    • Author(s)
      Ratta-Apha W, Hishimoto A, Mouri K, Shiroiwa K, Sasada T, Yoshida M, Supriyanto I, Ueno Y, Asano M, Shirakawa O, Togashi H, Takai Y, Sora I.
    • Journal Title

      Neurosci Res.

      Volume: 77 Issue: 4 Pages: 222-227

    • DOI

      10.1016/j.neures.2013.08.010

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005
  • [Journal Article] Nectin-like molecule-5 regulates intimal thickening after carotid artery ligation in mice.2013

    • Author(s)
      Kureha F, Satomi-Kobayashi S, Kubo Y, Kinugasa M, Ishida T, Takai Y, Hirata K, Rikitake Y.
    • Journal Title

      Arterioscler Thromb Vasc Biol.

      Volume: 33 Issue: 6 Pages: 1206-1211

    • DOI

      10.1161/atvbaha.113.301425

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-25461128
  • [Journal Article] Binding between the junctional proteins afadin and PLEKHA7 and implication in the formation of adherens junction in epithelial cells.2013

    • Author(s)
      Kurita S, Yamada T, Rikitsu E, Ikeda W, Takai Y.
    • Journal Title

      J Biol Chem.

      Volume: 288 Issue: 41 Pages: 29356-29368

    • DOI

      10.1074/jbc.m113.453464

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-24790283
  • [Journal Article] Genetic deletion of afadin causes hydrocephalus by destruction of adherens junctions in radial glial and ependymal cells in the midbrain.2013

    • Author(s)
      Yamamoto H, Maruo T, Majima T, Ishizaki H, Tanaka-Okamoto M, Miyoshi J, Mandai K, Takai Y.
    • Journal Title

      PLoS One.

      Volume: 8 Issue: 11 Pages: e80356-e80356

    • DOI

      10.1371/journal.pone.0080356

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PUBLICLY-24111532
  • [Journal Article] Regulation of dendritic filopodial interactions by ZO-1 and implications for dendrite morphogenesis.2013

    • Author(s)
      Komaki R, Togashi H, Takai Y.
    • Journal Title

      PLoS One.

      Volume: 8 Issue: 10 Pages: e76201-e76201

    • DOI

      10.1371/journal.pone.0076201

    • Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-21227005
  • [Journal Article] Statins exert pleiotropic effects through SmgGD S up-regulation with a resultant Rac l degradation2013

    • Author(s)
      Tanaka S, Fukumoto Y, Nochioka K, Minami T, Kudo S, Shiba N, Takai Y, Williams CL, Liao JK, Shimokawa H
    • Journal Title

      Arterioscter Thromz Vasc Biol

      Volume: (in press) Issue: 7 Pages: 1591-1600

    • DOI

      10.1161/atvbaha.112.300922

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-20117009, KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-22390154, KAKENHI-PROJECT-23659071, KAKENHI-PROJECT-25461100, KAKENHI-PROJECT-25670379
  • [Journal Article] Reduction of the ST6 β-galactosamide α-2,6-sialyltransferase 1 (ST6GAL1)-catalyzed sialylation of nectin-like molecule 2/cell adhesion molecule 1 and enhancement of ErbB2/ErbB3 signaling by microRNA-199a.2013

    • Author(s)
      Minami A, Shimono Y, Mizutani K, Nobutani K, Momose K, Azuma T, Takai Y.
    • Journal Title

      J Biol Chem.

      Volume: 288 Issue: 17 Pages: 11845-11853

    • DOI

      10.1074/jbc.m112.405993

    • NAID

      40019873148

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-23501268, KAKENHI-PROJECT-24790284, KAKENHI-PUBLICLY-23130510
  • [Journal Article] Necl-2/CADM1 interacts with ErbB4 and regulates its activity in GABAergic neurons.2013

    • Author(s)
      Yamada A, Inoue E, Deguchi-Tawarada M, Matsui C, Togawa A, Nakatani T, Ono Y, Takai Y.
    • Journal Title

      Mol Cell Neurosci.

      Volume: 56 Pages: 234-243

    • DOI

      10.1016/j.mcn.2013.06.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005
  • [Journal Article] Interaction of Necl-4/CADM4 with ErbB3 and integrin α6 β4 and inhibition of ErbB2/ErbB3 signaling and hemidesmosome disassembly.2013

    • Author(s)
      Sugiyama H, Mizutani K, Kurita S, Okimoto N, Shimono Y, Takai Y.
    • Journal Title

      Genes Cells.

      Volume: 18 Issue: 6 Pages: 519-528

    • DOI

      10.1111/gtc.12056

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005, KAKENHI-PROJECT-23501268, KAKENHI-PROJECT-24790284, KAKENHI-PUBLICLY-23130510
  • [Journal Article] Nectin and junctional adhesion molecule are critical cell adhesion molecules for the apico-basal alignment of adherens and tight junctions in epithelial cells.2013

    • Author(s)
      Yamada T, Kuramitsu K, Rikitsu E, Kurita S, Ikeda W, Takai Y.
    • Journal Title

      Genes Cells.

      Volume: 18 Issue: 11 Pages: 985-998

    • DOI

      10.1111/gtc.12091

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-21227005
  • [Journal Article] Laminin- based cell adhesion anchors microtubule plus ends to the epithelial cell basal cortex through LL5-α/(ss)□2010

    • Author(s)
      Hotta A, Kawakatsu T, Nakatani T, Sato T, Matsui C, Sukezane T, Akagi T, Hamaji T, Grigoriev I, Akhmanova A, Takai Y, Mimori-Kiyosue Y.
    • Journal Title

      J Cell Biol 189

      Pages: 901-917

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Involvement of the interaction of afadin with ZO-1 in the formation of tight junctions in MDCK cells.2010

    • Author(s)
      Ooshio T, Kobayashi R, Ikeda W, Miyata M, Fukumoto Y, Matsuzawa N, Ogita H, Takai Y.
    • Journal Title

      J Biol Chem 285

      Pages: 5003-5012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Localization of nectin-free afadin at the leading edge and its involvement in directional cell movement induced by platelet-derived growth factor.2009

    • Author(s)
      Miyata M, Ogita H, Komura H, Nakata S, Okamoto R, Ozaki M, Majima T, Matsuzawa N, Kawano S, Minami A, Waseda M, Fujita N, Mizutani K, Rikitake Y, Takai Y.
    • Journal Title

      J Cell Sci 122

      Pages: 4319-4329

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Regulation by afadin of cyclical activation and inactivation of Rap1, Rac1, and RhoA small G proteins at leading edges of moving NIH3T3 cells.2009

    • Author(s)
      Miyata M, Rikitake Y, Takahashi M. Nagamatsu Y, Yamauchi Y, Ogita H, Hirata, K, Takai, Y.
    • Journal Title

      J Biol Chem 284

      Pages: 24595-24609

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Synaptic activity prompts γ-secretase- mediated cleavage of EphA4 and dendritic spine formation.2009

    • Author(s)
      Inoue E, Deguchi-Tawarada M, Togawa A, Matsui C, Arita K, Katahira-Tayama S, Sato T, Yamauchi E, Oda Y, Takai Y.
    • Journal Title

      J Cell Biol 185

      Pages: 551-564

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Silencing of ErbB3/ErbB2 signaling by immunoglobulin-like Necl-2.2009

    • Author(s)
      Kawano S, Ikeda W, Kishimoto M, Ogita H, Takai Y.
    • Journal Title

      J Biol Chem 284

      Pages: 23793-23805

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Regulation by afadin of cyclical activation and inactivation of Rap1, Rac1, and RhoA small G proteins at leading edges of moving NIH3T3 cells.2009

    • Author(s)
      Miyata M, Rikitake Y, Takahashi M, Nagamatsu Y, Yamauchi Y, Ogita H, Hirata K, Takai Y.
    • Journal Title

      J Biol Chem. 284(36)

      Pages: 24595-24609

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16060101
  • [Journal Article] Nectins and nectin-like molecules: roles in contact inhibition of cell movement and proliferation2008

    • Author(s)
      Y. Takai, J. Miyoshi, W. Ikeda, H. Ogita
    • Journal Title

      Nat. Rev. Mol. Cell Biol. 9

      Pages: 603-615

    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] The immunoglobulin-like cell adhesion molecule nectin and its associated protein afadin.2008

    • Author(s)
      Takai Y, Ikeda W, Ogita H, Rikitake Y.
    • Journal Title

      Annu Rev Cell Dev Biol 24

      Pages: 309-342

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Nectins and nectin-like molecules: roles in contact inhibition of cell movement and proliferation.2008

    • Author(s)
      Takai Y, Miyoshi J, Ikeda W, Ogita H.
    • Journal Title

      Nat Rev Mol Cell Biol. 9(8)

      Pages: 603-615

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16060101
  • [Journal Article] Roles of Necl-5/Poliovirus receptor and ROCK in the regulation of transformation of integrin αv(ss)3-based focal complexes into focal adhesions.2008

    • Author(s)
      Nagamatsu Y, Rikitake Y, Takahashi M, Deki Y, Ikeda W, Hirata K, Takai Y.
    • Journal Title

      J Biol Chem 283

      Pages: 14532-14541

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Cross-talk among integrin, cadherin, and growth factor Receptor: roles of nectin and nectin-like molecule.2008

    • Author(s)
      Ogita H, Takai Y.
    • Journal Title

      Int Rev Cytol 265

      Pages: 1-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] The Immunoglobulin-like cell adhesion molecule nectin and its associated protein afadin2008

    • Author(s)
      Takai, Y.
    • Journal Title

      Annu. Rev. Cell Dev. Biol 24

      Pages: 309-342

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Nectins and nectin-like molecules : roles in contact inhibition of cell movement and proliferation2008

    • Author(s)
      Takai, Y.
    • Journal Title

      Nat. Rev. Mol. Cell Biol 9

      Pages: 603-615

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Nectins and nectin-like molecules : roles in contact inhibition of cell movement and proliferation.2008

    • Author(s)
      Takai Y, Miyoshi J, Ikeda W, Ogita H.
    • Journal Title

      Nat Rev Mol Cell Biol 9

      Pages: 603-615

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Nectins and nectin-like molecules : roles in contact inhibition of cell movement and proliferation2008

    • Author(s)
      Takai, Y.
    • Journal Title

      Nat. Rev. Mol. Cell Biol 9

      Pages: 603-615

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16060101
  • [Journal Article] Dual inhibition of SNARE complex formation by tomosyn ensures controlled neurotransmitter release.2008

    • Author(s)
      Sakisaka T, Yamamoto Y, Mochida S, Nakamura M, Nishikawa K, Ishizaki H, Okamoto-Tanaka M, Miyoshi J, Fujiyoshi Y, Manabe T, Takai, Y.
    • Journal Title

      J Cell Biol 183

      Pages: 323-337

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Involvement of nectin in inactivation of integrin αvss3 after the establishment of cell-cell adhesion.2008

    • Author(s)
      Sakamoto Y, Ogita H, Komura H, Takai Y.
    • Journal Title

      J Biol Chem 283

      Pages: 496-505

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Regulation of platelet-derived growth factor receptor activation by afadin through SHP-2 : implications for cellular morphology.2007

    • Author(s)
      Nakata S, Fujita N, Kitagawa Y, Okamoto R, Ogita H, Takai Y.
    • Journal Title

      J Biol Chem 282

      Pages: 37815-37825

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Necl-5/poliovirus receptor interacts in cis with integrin αvss3 and regulates its clustering and focal complex formation.2007

    • Author(s)
      Minami Y, Ikeda W, Kajita M, Fujito T, Amano H, Tamaru Y, Kuramitsu K, Sakamoto Y, Monden M, Takai, Y.
    • Journal Title

      J Biol Chem 282

      Pages: 18481-18496

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Rap1-PDZ-GEF1 interacts with a neurotrophin receptor at late endosomes, leading to sustained activation of Rap1 and ERK and neurite outgrowth.2007

    • Author(s)
      Hisata S, Sakisaka T, Baba T, Yamada T, Aoki K, Matsuda M, Takai Y.
    • Journal Title

      J Cell Biol 178

      Pages: 843-860

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Regulation of platelet-derived growth factor receptor activation by afadin through SHP-2: implications for cellular morphology.2007

    • Author(s)
      S. Nakata, Y. Takai, et. al. (total 6, last)
    • Journal Title

      J. Biol. Chem. 282

      Pages: 37815-37825

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] Cooperative roles of Par-3 and afadin in the formation of adherens and tight junctions.2007

    • Author(s)
      Ooshio T, Fujita N, Yamada A, Sato T, Kitagawa Y, Okamoto R, Nakata S, Miki A, Irie K, Takai Y.
    • Journal Title

      J Cell Sci 120

      Pages: 2352-2365

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] The roles of nectins in cell adhesions : cooperation with other cell adhesion molecules and growth factor receptors.2007

    • Author(s)
      Sakisaka T, Ikeda W, Ogita H, Fujita N, Takai Y.
    • Journal Title

      Curr Opin Cell Biol 19

      Pages: 593-602

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Up-regulation of loricrin expression by cell adhesion molecule nectin-1 through Rap1-ERK signaling in keratinocytes.2007

    • Author(s)
      Wakamatsu K, Ogita H, Okabe N, Irie K, Tanaka-Okamoto M, Ishizaki H, Ishida-Yamamoto A, Iizuka H, Miyoshi J, Takai, Y.
    • Journal Title

      J Biol Chem 282

      Pages: 18173-18181

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Regulation of platelet-derived growth factor receptor activation by afadin through SHP-2:implications for cellular morphology.2007

    • Author(s)
      Nakata, S., Fujia, N., Kitagawa, Y., Okamoto, R., Ogita, H. and Takai, Y.
    • Journal Title

      J Biol Chem. 282(52)

      Pages: 37815-37825

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16058101
  • [Journal Article] Activation of Rac by cadherin through the c-Src-Rap1- phosphatidylinositol 3-kinase-Vav2 pathway.2006

    • Author(s)
      Fukuyama T, Ogita H, Kawakatsu T, Inagaki M, Takai Y.
    • Journal Title

      Oncogene 25

      Pages: 8-19

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Involvement of the Ras-Ras-activated Rab5 guanine nucleotide exchange factor RIN2-Rab5 pathway in the Hepatocyte Growth Factor-induced endocytosis of E-cadherin.2006

    • Author(s)
      Kimura T, Sakisaka T, Baba T, Yamada T, Takai Y.
    • Journal Title

      J Biol Chem 281

      Pages: 10598-10609

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Interaction of integrin avb3 with nectin : implication in cross-talk between cell-matrix and cell-cell junctions.2006

    • Author(s)
      Sakamoto, Y., Ogita, H., Hirota, T., Kawakatsu, T., Fukuyama, T., Yasumi, M., Kanzaki, N., Ozaki, M., Takai, Y.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 19631-19644

    • Data Source
      KAKENHI-PROJECT-16058101
  • [Journal Article] Regulation of the assembly and adhesion activity of E-cadherin by nectin and afadin for the formation of adherens junctions in Madin-Darby Canine Kidney Cells.2006

    • Author(s)
      Sato T, Fujita N, Yamada A, Ooshio T, Okamoto R, Irie K, Takai, Y.
    • Journal Title

      J Biol Chem 281

      Pages: 5288-5299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Requirement of nectin, but not cadherin, for formation of claudin- based tight junctions in annexin II- knockdown MDCK cells.2006

    • Author(s)
      Yamada A, Fujita N, Sato T, Okamoto R, Ooshio T, Hirota T, Morimoto K, Irie K, Takai Y.
    • Journal Title

      Oncogene 25

      Pages: 5085-5102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Interaction of integrin αvss3 with nectin : Implication in cross-talk between cell-matrix and cell-cell junctions.2006

    • Author(s)
      Sakamoto Y, Ogita H, Hirota T, Kawakatsu T, Fukuyama T, Yasumi M, Kanzaki N, Ozaki M, Takai Y.
    • Journal Title

      J Biol Chem 281

      Pages: 19631-19644

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Journal Article] Interaction of integrin avb3 with nectin : implication in cross-talk between cell-matrix and cell-cell junctions.2006

    • Author(s)
      Y.Sakamoto, Y.Takai et al.(total 9, last)
    • Journal Title

      J. Biol. Chem. 281(28)

      Pages: 19631-19644

    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] Inhibition of cell movement and proliferation by cell-cell contact-induced interaction of Nec1-5 with nectin-32005

    • Author(s)
      T. Fujito, W. Ikeda, S. Kakunaga, Y. Minami, M. Kajita, Y. Sakamoto, M. Monden, Y. Takai
    • Journal Title

      J. Cell Biol. 171

      Pages: 165-173

    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] Inhibition of cell movement and proliferation by cell-cell contact-induced interaction of Necl-5 with nectin-3.2005

    • Author(s)
      T.Fujito, Y.Takai et al.(total 8, last)
    • Journal Title

      J.Cell Biol. 171(1)

      Pages: 165-173

    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] Inhibition of cell movement and proliferation by cell-cell contact-induced interaction of Nec1-5 with pectin-3.2005

    • Author(s)
      Fujito T, Takai Y
    • Journal Title

      J Cell Biol. 171巻1号

      Pages: 165-173

    • Data Source
      KAKENHI-PROJECT-16058101
  • [Journal Article] Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG.2004

    • Author(s)
      Fukuhara, T., Shimizu, K., Kawakatsu, T., Fukuyama, T., Minami, Y., Honda, T., Hoshino, T., Yamada, T., Ogita, H., Okada, M., Takai, Y.
    • Journal Title

      J.Cell Biol. 166

      Pages: 393-405

    • Data Source
      KAKENHI-PROJECT-16058101
  • [Journal Article] Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG.2004

    • Author(s)
      Y.Takai.(他10名)
    • Journal Title

      J.Cell Blol. 166(3)

      Pages: 393-405

    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] Enhancement of serum- and platelet-derived growth factor-induced cell proliferation by Necl-5/Tage4/Poliovirus Receptor/CD155 through the Ras-Raf-MEK-ERK signaling.2004

    • Author(s)
      Y.Takai.(他7名)
    • Journal Title

      J.Biol.Chem. 279(35)

      Pages: 36419-36423

    • Data Source
      KAKENHI-PROJECT-16059101
  • [Patent] ErbB3活性化に伴うシグナルの伝達抑制物質及びそのスクリーニング方法2016

    • Inventor(s)
      高井義美、水谷清人、慶田城迅
    • Industrial Property Rights Holder
      高井義美、水谷清人、慶田城迅
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-096427
    • Filing Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Patent] ErbB3活性化に伴うシグナルの伝達抑制物質及びそのスクリーニング方法2016

    • Inventor(s)
      高井義美、水谷清人、慶田城迅
    • Industrial Property Rights Holder
      国立大学法人神戸大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-096427
    • Filing Date
      2016-05-12
    • Data Source
      KAKENHI-PLANNED-26114007
  • [Presentation] ネクチン-2αとマウス手綱核2016

    • Author(s)
      塩谷元、萬代研二、宮田宗明、丸尾知彦、垣内愛加、王淑杰、藤原武志、溝口明、望月秀樹、高井義美
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Presentation] Roles of afadin in the development of the cellular architecture of the hippocampus.2016

    • Author(s)
      宮田宗明、丸尾知彦、山本昆明、垣内愛加、王淑杰、藤原武志、溝口明、萬代研二、高井義美
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Presentation] 転移乳がんにおけるCXCR4の発現低下とがん休眠との関連2015

    • Author(s)
      上田悠貴、信谷健太郎、下野洋平、水谷清人、鈴木俊裕、北山美登里、南晶洋、百瀬健次、宮脇恒太、赤司浩一、東健、高井義美
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PLANNED-26114007
  • [Presentation] 細胞の接着とシグナル伝達2015

    • Author(s)
      高井義美
    • Organizer
      第38回日本分子生物学会年会 第88回日本生化学会大会 合同大会(BMB2015)
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PLANNED-26114007
  • [Presentation] AdAMS: Activith-dependent alteration of morphology of a hippocampal mossy fiber bouton.2015

    • Author(s)
      Maruo Tomohiko, Mandai Kenji, Takai Yoshimi, Mori Masahiro
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2015-07-28
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Presentation] SBF-SEM 3D reconstitution analysis reveals alterations in composition and morphology of mouse hippocampal mossy fiber synapses by afadin knockout2015

    • Author(s)
      Takeshi Fujiwara, Shujie Wang, Yu Itoh, Kousyoku Sai, Aika Kaito, Naoyuki Miyazaki, Kazuyoshi Murata, Tomohiko Maruo, Hideaki Yamamoto, Kenji Mandai, Yoshimi Takai, Akira Mizoguchi
    • Organizer
      第120回日本解剖学会総会・全国学術集会・第92回日本生理学会大会合同大会
    • Place of Presentation
      神戸国際会議場・展示場
    • Year and Date
      2015-03-21
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Presentation] 乳腺分化を制御する新規のネクチン依存性細胞間接着装置2015

    • Author(s)
      圓岡真宏、北山-吉田美登里、水谷清人、高井義美
    • Organizer
      第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会  (BMB2015)
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Presentation] 細胞の接着とシグナル伝達2015

    • Author(s)
      高井義美
    • Organizer
      第38回日本分子生物学会年会・第88回日本生化学会大会 合同大会 (BMB2015)
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Presentation] 乳腺分化を制御する新規のネクチン依存性細胞間接着装置2015

    • Author(s)
      圓岡真宏、北山美登里、水谷清人、高井義美
    • Organizer
      第38回日本分子生物学会年会 第88回日本生化学会大会 合同大会(BMB2015)
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PLANNED-26114007
  • [Presentation] 転移乳がん細胞におけるCXCR4の発現低下とがん休眠との関連2015

    • Author(s)
      上田悠貴、信谷健太郎、下野洋平、水谷清人、鈴木俊裕、北山美登里、南晶洋、百瀬健次、宮脇恒太、赤司浩一、東健、高井義美
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Presentation] 細胞のがん化と細胞接着装置2011

    • Author(s)
      高井義美
    • Organizer
      第70回日本癌学会学術総会 モーニングレクチャー
    • Place of Presentation
      名古屋
    • Invited
    • Data Source
      KAKENHI-PROJECT-21227005
  • [Presentation] 異種細胞間接着形成におけるネクチンの機能と作用機構2011

    • Author(s)
      高井義美
    • Organizer
      第28回日本医学会総会2011
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-21227005
  • [Presentation] Roles and modes of action of nectin in adhesion between heterogeneous cells.2011

    • Author(s)
      Yoshimi Takai
    • Organizer
      Gordon Research Conference on Cell Contact & Adhesion 2011
    • Place of Presentation
      Vermont, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-21227005
  • [Presentation] Roles of nectins in heterotypic cell adhesion.2011

    • Author(s)
      Yoshimi Takai
    • Organizer
      5th Mechanobiology Conference 2011
    • Place of Presentation
      Singapore
    • Invited
    • Data Source
      KAKENHI-PROJECT-21227005
  • [Presentation] Regulatory Mechanism of Active Zone Formation by Nectin-Afadin Adhesion System2009

    • Author(s)
      Yoshimi Takai
    • Organizer
      "Current Trends in Biomedicine"workshop"Active Zones as organizers of neuronal communication"
    • Place of Presentation
      UNIA(Spain)
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-21227005
  • [Presentation] Regulatory Mechanism of Active Zone Formation by Nectin-Afadin Adhesion System2009

    • Author(s)
      Yoshimi Takai
    • Organizer
      "Current Trends in Biomedicine" workshop "Active Zones as organizers of neuronal communication"
    • Place of Presentation
      Spain, Baeza
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Regulatory Mechanism of Active Zone Formation by Nectin-Afadin Adhesion System.2009

    • Author(s)
      Y.Takai
    • Organizer
      "Current Trends, in Biomedicine" workshop "Active Zones as organizers of neuronal communication"
    • Place of Presentation
      UNIA(Spain)
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-16060101
  • [Presentation] Nectins and nectin-like molecules: roles and modes of action in tumorigenesis, nvasion, and metastasis.2009

    • Author(s)
      高井義美
    • Organizer
      Global COE Inter- national Symposium "New Aspects in Immunology and Cancer Research"
    • Place of Presentation
      Akita, Japan
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Nectins and nectin-like molecules : roles and modes of action in tumorigenesis, invasion, and metastasis2009

    • Author(s)
      Yoshimi Takai
    • Organizer
      Global COE International Symposium "New Aspects in Immunology and Cancer Research"
    • Place of Presentation
      秋田大学(秋田県)
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Nectins and nectin-like molecules : roles and modes of action in tumorigenesis, invasion, and metastasis2009

    • Author(s)
      Yoshimi Takai
    • Organizer
      Global COE international Symposium"New Aspects in Immunology and Cancer Research"
    • Place of Presentation
      秋田大学(秋田県)
    • Year and Date
      2009-06-25
    • Data Source
      KAKENHI-PROJECT-21227005
  • [Presentation] 細胞の極性形成の基本メカニズム2008

    • Author(s)
      高井義美
    • Organizer
      第8回日本分子生物学会春季シンポジウム
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] 細胞接着とシグナル伝達-生理機能と病態2008

    • Author(s)
      高井義美
    • Organizer
      第31回日本血栓止血学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2008-11-21
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] 細胞接着とシグナル伝達-生理機能と病態2008

    • Author(s)
      高井義美
    • Organizer
      第31回日本血栓止血 学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Roles and modes of action of nectins and afadin in synaptogenesis2008

    • Author(s)
      Yoshimi Takai
    • Organizer
      FENS 2008 Satellite Symposium "Cell-cell adhesion mechanisms : From development of synaptic networks to cognitive dysfunction"
    • Place of Presentation
      Switzerland (Geneva)
    • Year and Date
      2008-07-10
    • Data Source
      KAKENHI-PROJECT-16060101
  • [Presentation] がん化による細胞接着・運動・増殖異常とその分子機構2008

    • Author(s)
      扇田久和、高井義美
    • Organizer
      第67回日本癌学会総会(シンポジウム)
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Roles and modes of action of nectins and afadin in synaptogenesis2008

    • Author(s)
      Yoshimi Takai
    • Organizer
      FENS 2008 Satellite Symposium "Cell-cell adhesion mechanisms : From development of synaptic networks to cognitive dysfunction"
    • Place of Presentation
      Switzerland (Geneva)
    • Year and Date
      2008-07-10
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] 細胞接着とシグナル伝達・生理機能と病態2008

    • Author(s)
      高井義美
    • Organizer
      第58回日本薬学会近畿支部総会・大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-10-25
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] 細胞の接着とシグナリング機構2007

    • Author(s)
      高井義美
    • Organizer
      日本生化学会東北支部第73回例会(シンポジウム)
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] 細胞の接着とシグナリング機構2007

    • Author(s)
      高井 義美
    • Organizer
      日本生化学会東北支部第73回例会
    • Place of Presentation
      仙台
    • Year and Date
      2007-05-12
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Cell-cell adhesion and formation of cell polarity2007

    • Author(s)
      高井 義美
    • Organizer
      第66回日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-03
    • Data Source
      KAKENHI-PROJECT-16060101
  • [Presentation] Cross-talk between cell-cell and cell-matrix junctions through nectin and nectin-like molecule2007

    • Author(s)
      高井 義美
    • Organizer
      Research Conferences"Cell Contact&Adhesion"
    • Place of Presentation
      Lucca, Italy
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Cell-cell adhesion and formation of cell polarity2007

    • Author(s)
      高井義美
    • Organizer
      第66回日本癌学会学術総会(シンポジウム)
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Cell adhesion and signal transduction2007

    • Author(s)
      高井 義美
    • Organizer
      Mini-symposium to celebrate 30thanniversary of Institute of Biological Chemistry(IBC)Proteins-from chemistry to biology
    • Place of Presentation
      Taiwan
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Cross-talk between cell-cell and cell-matrix junctions through nectin and nectin-like molecule2007

    • Author(s)
      高井 義美
    • Organizer
      Research ConferencesCell Contact & Adhesion
    • Place of Presentation
      Lucca, Italy
    • Data Source
      KAKENHI-PROJECT-16060101
  • [Presentation] Roles of nectin and nectin-like molecule in contact inhibition of cell movement2007

    • Author(s)
      高井 義美
    • Organizer
      6th Abercrombie Meeting on Cell Migration: from molecules to organisms
    • Place of Presentation
      Oxford
    • Data Source
      KAKENHI-PROJECT-16060101
  • [Presentation] Roles of nectin and nectin-like molecule in contact inhibition of cell movement2007

    • Author(s)
      Takai Y.
    • Organizer
      6th Abercrombie Meeting on Cell Migration: from molecules to organisms.
    • Place of Presentation
      Oxford, UK.
    • Year and Date
      2007-09-09
    • Data Source
      KAKENHI-PROJECT-16060101
  • [Presentation] Roles and modes of action of nectin and nectin-like molecule in cell polarization.2007

    • Author(s)
      高井義美
    • Organizer
      International Symposium on Cell Polarity System and Future Medicine "Revealing the Mechanism of Cell Morphogenesis for Future Medicine"
    • Place of Presentation
      Yokohama, Japan
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] 細胞間接着による細胞の運動・増殖機構2007

    • Author(s)
      高井義美
    • Organizer
      第39回日本結合組織学会・第54回日本マトリックス研究会合同学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Cell adhesion and signal Transduction.2007

    • Author(s)
      高井義美
    • Organizer
      Mini-symposium to celebrate 30th anniversary of Institute of Biological Chemistry (IBC) "Proteins from chemistry to biology"
    • Place of Presentation
      Taiwan
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Cross-talk between cell-cell and cell-matrix junctions through nectin and nectin-like molecule.2007

    • Author(s)
      高井義美
    • Organizer
      Gordon Research Conferences "Cell Contact & Adhesion"
    • Place of Presentation
      Lucca, Italy
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Cell-cell adhesion and formation of cell polarity2007

    • Author(s)
      高井 義美
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Roles of nectin and nectin-like molecule in contact inhibition of cell movement.2007

    • Author(s)
      高井義美
    • Organizer
      6th Abercrombie Meeting on Cell Migration : from molecules to organisms
    • Place of Presentation
      Oxford, UK
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Cooperative roles of Par-3 and afadin in the formation of adherens and tight junctions2007

    • Author(s)
      高井 義美
    • Organizer
      International Symposium on Cell Polarity System and Future MedicineRevealing the Mechanism of Cell Morohogenesis for Future Medicine
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Roles of nectin and nectin-like molecule in contact inhibition of cell movement2007

    • Author(s)
      高井 義美
    • Organizer
      6th Abercrombie Meeting on Cell Migration:from molecules to organisms.
    • Place of Presentation
      Oxford
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Cell adhesion and signal transduction2007

    • Author(s)
      高井義美
    • Organizer
      第71回日本循環器学会総会(真下記念講演)
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Nectin and nectin-like molecules in cell adhesion, movement, and proliferation.2006

    • Author(s)
      高井義美
    • Organizer
      The 55th Fujihara International Seminar "Physiological and pathological significance of the cell to cell interaction by TSLC1/1GSF4"
    • Place of Presentation
      Hokkaido, Japan
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Regulation of cell polarization, movement, and proliferation by cell-cell adhesion molecule nectin.2006

    • Author(s)
      高井義美, 藤田直之, 扇田久和, 池田わたる
    • Organizer
      20^<th> IUBMB International Congress of Biochemistry and Molecular Biology and 11^<th> FAOBMB Congress
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] がん細胞の異常増殖と浸潤・転移の分子機構2006

    • Author(s)
      高井義美
    • Organizer
      第65回日本癌学会学術総会(モーニングレクチャー)
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] 月田先生から学んだ私の細胞接着研究2006

    • Author(s)
      高井義美
    • Organizer
      第3次対がん10か年総合戦略(平成16年度-25年度)第1回合同シンポジウム
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] New cross-talk mechanisms of cell adhesion, migration and proliferation.2006

    • Author(s)
      高井義美, 池田わたる, 扇田久和, 匂坂敏朗, 藤田直之
    • Organizer
      The 10th International Symposium on Cancer Chemotherapy "Growth Signal, Drug Resistance and Metastasis in the Development of Molecular Cancer Therapeutics"
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Temporal and spatial control of intracellular signaling.2005

    • Author(s)
      高井義美
    • Organizer
      Inter- national Symposium on Leading Project for Biosimulation
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Signaling by nectins and nectin-like molecules in cell adhesion, migration and proliferation.2005

    • Author(s)
      高井義美
    • Organizer
      Gordon Research Conferences "Mechanisms of Cell Signalling"
    • Place of Presentation
      Hong Kong
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] Cross-talk signaling between cell adhesion and cell movement and proliferation2005

    • Author(s)
      高井義美、池田わたる、扇田久和、匂坂敏朗、藤田直之
    • Organizer
      第78回日本生化学会大会(シンポジウム)
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] がん細胞の浸潤・転移の新しい分子機構2005

    • Author(s)
      高井義美
    • Organizer
      第14回日本がん転移学会総会(特別講演)
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] がん細胞の接着と極性の異常2005

    • Author(s)
      高井義美
    • Organizer
      第64回日本癌学会学術総会(モーニングレクチャー)
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-17014055
  • [Presentation] マイクロRNA-199aはTGFβ-1で誘導されるSNAI1とN-cadherinの発現を 抑制する

    • Author(s)
      鈴木俊裕、水谷清人、南晶洋、信谷健太郎、梛野正人、下野洋平、 高井義美
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Presentation] Afadin-deficiency leads to the formation of double cortex by abnormal radial glial scaffold and cell-autonomous impairment of neuronal migration during development.

    • Author(s)
      Hideaki Yamamoto, Kenji Mandai, Daijiro Konno, Tomohiko Maruo, Fumio Matsuzaki, Yoshimi Takai
    • Organizer
      2014 CSHL Conference on Glia in Health & Disease
    • Place of Presentation
      New York, NY, USA
    • Year and Date
      2014-07-17 – 2014-07-21
    • Data Source
      KAKENHI-PROJECT-21227005
  • [Presentation] SBF-SEM 3D reconstitution analysis reveals alterations in composition and morphology of mouse hippocampal mossy fiber synapses by afadin knockout.

    • Author(s)
      Takeshi Fujiwara, Shujie Wang, Yu Itoh, Kousyoku Sai, Aika Kaito, Naoyuki Miyazaki, Kazuyoshi Murata, Tomohiko Maruo, Hideaki Yamamoto, Kenji Mandai, Yoshimi Takai, Akira Mizoguchi
    • Organizer
      第120回日本解剖学会総会・全国学術集会・第92回日本生理学会大会合同大会
    • Place of Presentation
      神戸国際会議場・展示場
    • Year and Date
      2015-03-21 – 2015-03-23
    • Data Source
      KAKENHI-PLANNED-26114007
  • [Presentation] マイクロRNA-199aはTGFβ-1で誘導されるSNAI1とN-cadherinの発現を抑制する

    • Author(s)
      鈴木俊裕、水谷清人、南晶洋、信谷健太郎、梛野正人、下野洋平、高井義美
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-21227005
  • [Presentation] Nectins Regulate the Mosaic Cellular Pattern Formation in the Olfactory Epithelium.

    • Author(s)
      Sayaka Katsunuma, Hideru Togashi , Ken-ichi Nibu and Yoshimi Takai
    • Organizer
      16th Asian Research Symposium in Rhinology (ARSR)
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2013-08-29 – 2013-08-31
    • Data Source
      KAKENHI-PROJECT-21227005
  • [Presentation] シグナル伝達と細胞接着―研究の歴史と展望―

    • Author(s)
      高井義美
    • Organizer
      第100回日本消化器病学会総会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2014-04-23 – 2014-04-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Presentation] Afadin plays an important role in formation of puncta adherentia junction and differentiation of presynapses in hippocampal neurons.

    • Author(s)
      Daisaku Toyoshima, Kenji Mandai, Tomohiko Maruo, Irwan Supriyanto, Hideru Togashi, Takahito Inoue, Masahiro Mori, Yoshimi Takai
    • Organizer
      Neuroscience 2014
    • Place of Presentation
      Washington, DC, USA
    • Year and Date
      2014-11-15 – 2014-11-19
    • Data Source
      KAKENHI-PROJECT-21227005
  • [Presentation] Afadin plays an important role in formation of puncta adherentia junction and differentiation of presynapses in hippocampal neurons.

    • Author(s)
      Daisaku Toyoshima, Kenji Mandai, Tomohiko Maruo, Irwan Supriyanto, Hideru Togashi, Takahito Inoue, Masahiro Mori, Yoshimi Takai
    • Organizer
      Neuroscience 2014
    • Place of Presentation
      Washington, DC, USA
    • Year and Date
      2014-11-15 – 2014-11-19
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Presentation] Afadin-deficiency leads to the formation of double cortex by abnormal radial glial scaffold and cell-autonomous impairment of neuronal migration during development.

    • Author(s)
      Hideaki Yamamoto, Kenji Mandai, Daijiro Konno, Tomohiko Maruo, Fumio Matsuzaki, Yoshimi Takai
    • Organizer
      2014 CSHL Conference on Glia in Health & Disease
    • Place of Presentation
      New York, NY, USA
    • Year and Date
      2014-07-17 – 2014-07-21
    • Data Source
      KAKENHI-PROJECT-26251013
  • [Presentation] Afadin-deficiency leads to the formation of double cortex by abnormal radial glial scaffold and cell-autonomous impairment of neuronal migration during development.

    • Author(s)
      Hideaki Yamamoto, Kenji Mandai, Daijiro Konno, Tomohiko Maruo, Fumio Matsuzaki, Yoshimi Takai
    • Organizer
      2014 CSHL Conference on Glia in Health & Disease
    • Place of Presentation
      New York, NY, USA
    • Year and Date
      2014-07-17 – 2014-07-21
    • Data Source
      KAKENHI-PLANNED-26114007
  • [Presentation] シグナル伝達と細胞接着―研究の歴史と展望―

    • Author(s)
      高井義美
    • Organizer
      第100回日本消化器病学会総会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2014-04-23 – 2014-04-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-21227005
  • [Presentation] マイクロRNA-199aはTGFβ-1で誘導されるSNAI1とN-cadherinの発現を抑制する

    • Author(s)
      鈴木俊裕、水谷清人、南晶洋、信谷健太郎、梛野正人、下野洋平、高井義美
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PLANNED-26114007
  • [Presentation] SBF-SEM 3D reconstitution analysis reveals alterations in composition and morphology of mouse hippocampal mossy fiber synapses by afadin knockout.

    • Author(s)
      Takeshi Fujiwara, Shujie Wang, Yu Itoh, Kousyoku Sai, Aika Kaito, Naoyuki Miyazaki, Kazuyoshi Murata, Tomohiko Maruo, Hideaki Yamamoto, Kenji Mandai, Yoshimi Takai, Akira Mizoguchi
    • Organizer
      第120回日本解剖学会総会・全国学術集会・第92回日本生理学会大会合同大会
    • Place of Presentation
      神戸国際会議場・展示場
    • Year and Date
      2015-03-21 – 2015-03-23
    • Data Source
      KAKENHI-PROJECT-21227005
  • [Presentation] Afadin plays an important role in formation of puncta adherentia junction and differentiation of presynapses in hippocampal neurons.

    • Author(s)
      Daisaku Toyoshima, Kenji Mandai, Tomohiko Maruo, Irwan Supriyanto, Hideru Togashi, Takahito Inoue, Masahiro Mori, Yoshimi Takai
    • Organizer
      Neuroscience 2014
    • Place of Presentation
      Washington, DC, USA
    • Year and Date
      2014-11-15 – 2014-11-19
    • Data Source
      KAKENHI-PLANNED-26114007
  • [Presentation] Nectin and afadin in cell adhesion and signaling.

    • Author(s)
      Yoshimi Takai
    • Organizer
      Symposium on Membrane Biology, Univesity of Washington and Kobe University
    • Place of Presentation
      Seattle, WA, USA
    • Year and Date
      2014-03-27 – 2014-03-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-21227005
  • 1.  KAIBUCHI Kozo (00169377)
    # of Collaborated Projects: 18 results
    # of Collaborated Products: 0 results
  • 2.  SASAKI Takuya (40241278)
    # of Collaborated Projects: 16 results
    # of Collaborated Products: 0 results
  • 3.  KIKUCHI Akira (10204827)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 0 results
  • 4.  KAWAHARA Yasuhiro (80169755)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 5.  YAMASHITA Takayuki (10166671)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 6.  TANIGUCHI Tadatsgu (50133616)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 7.  MIZOGUCHI Akira (90181916)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 12 results
  • 8.  TANAKA Kazuma (60188290)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 9.  KAWATA Masahito (20224785)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 10.  NOZAWA Yoshinori (10021362)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 11.  SHIRATAKI Hiromichi (90249962)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 12.  TSURUO Tahashi (00012667)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 13.  河合 忠一 (70025659)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 14.  渋谷 正史 (10107427)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 15.  KATADA Toshiaki (10088859)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 16.  TSUKITA Shoichiro (50155347)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 17.  鈴木 紘一 (80011948)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 18.  吉田 光昭 (80012607)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 19.  SASAZUKI Takehiko (50014121)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 20.  NAKAMURA Yusuke (70217909)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 21.  AKIYAMA Tetsu (70150745)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 22.  SEIKI Motoharu (10154634)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 23.  IKEDA Wataru (90362699)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 12 results
  • 24.  OGITA Hisakazu (50379236)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 19 results
  • 25.  NAKAMURA Takuro (00180373)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 26.  OKAMOTO Miki (20332455)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 27.  日高 弘義 (80100171)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 28.  芹澤 剛 (90143429)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 29.  水上 茂樹 (90037325)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 30.  豊岡 照彦 (00146151)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 31.  豊島 久真男 (90029760)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 32.  井村 裕夫 (10025570)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 33.  北 徹 (60161460)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 34.  MATSUMOTO Kunihiro (70116375)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 35.  NARUMIYA Shuh (70144350)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 36.  UI Michio (50001037)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 37.  SAKISAKA Toshiaki (80359843)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 38.  NODA Tetsuo (10183550)
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