Niwa Ohtsura 丹羽太貫

… Alternative Names

Researcher Number	80093293
Other IDs
Affiliation (Current)	2019 : 公益財団法人放射線影響研究所, , 理事
Affiliation (based on the past Project Information) *help	2009 – 2010 : 放射線医学総合研究所, 重粒子医科学センター, 副センター長 2009 : 放射線医学研究所, 重粒子医科学センター 2008 : 鳥取大学, 放射線医学総合研究所重粒子医科学センター, 副センター長 2007 : National Institute of Radiological Sciences, Research Center for Particle Radiotherapy, Deputy Director 1997 – 2006 : Kyoto University, Radiation Biology Center, Professor, 放射線生物研究センター, 教授 … More
Review Section/Research Field	Principal Investigator 環境影響評価(含放射線生物学) / Risk sciences of radiation/Chemicals / Experimental pathology Except Principal Investigator 環境影響評価(含放射線生物学) / 放射線5生物学 / Biological Sciences / Experimental pathology / Statistical science / Radiation science / 遺伝 / Living organism molecular science / Hematology
Keywords	Principal Investigator ゲノム不安定性 / 放射線 / p53 / 遺伝的不安定性 / pink-eyed unstable allele / 遅延突然変異 / p53依存性Sチェックポイント / ミニサテライト / Transforming RNA / ミニサテライト配列 … More Except Principal Investigator 放射線 / マウス / テラトカルシノーマ / 胚性腫瘍細胞 / 遺伝的不安定性 / がん遺伝子 / 増殖因子 / 成長因子 / ゲノム不安定性 / 放射線応答 / 突然変異 / 放射線影響 / 胚性腫瘍 / 放射線発がん / レチノイン酸 / 遺伝子破壊 / 遺伝子発現 / 枯死遺伝子 / ES細胞 / 細胞分化 / オクタマ-配列 / 情報伝達 / ミニサテライト遺伝子 / SDF-II / 慢性骨髄性白血病 / RAD54 / 乳腺上皮細胞 / VL30 / EC細胞 / Fv-4 / テラト-マ / 発がん過程 / 優性遺伝 / 染色体異常 / シグナル伝達 / p53 / 細胞内情報伝達 / 悪性腫瘍 / 分化 / 高発がん突然変異 / 遺伝子トラップ / TPA / 生殖細胞突然変異 / HIV / 線量反応関係 / 遺伝子 / 原爆被爆者 / 発生工学 / 糖タンパク質 / Tumor growth / Tumorigenicity screening / 生理活性物質 / Chromosome abnormality / 先導的居住環境 / 確率過程 / DNA2重鎖切断 / 試験管内発癌 / Space Environment / apoptosis / 染色体 / 骨萎縮 / 継世代発がん / TLD測定 / homeostasis / 急性白血病 / 死因調査 / 適応 / Mathematical model / RAS遺伝子 / モロニー白血病ウイルス / 遺伝子改変マウス / レトロトランスポゾン / Genomic Instability / Risk analysis / bcr再構成 / 放射線感受性遺伝子 / VEGF / 磁場 / トランスジェニックマウス / 遺伝子的不安定性 / 磁場による突然変異 / ウィルス / 染色体外プロウイルス / Multi-target model / Genomic instabnility / ウイルス / 環境要因 / Transforming gene / ポリオーマウイルス / 癌 / Philadelphia染色体 / cellcycle / 細胞周期制御 / Polymerase chain reaction / Shuttle vector / 大気汚染 / Radiation effect / 相同的組み替え / 肝癌細胞株 / 細胞組織 / Fv4 / 細胞周期 / Cause of death among A-bomb survivors / Radiation response / 免疫グロブリン遺伝子スーパーファミリー / genetic instability / 変異原性試験 / gene expression / ヒトにおける中性子のリスク評価 / サプレッサーtRNA / 細胞死 / V(D)J組換え / 酸化的DNA損傷 / リスク解析 / 低線量・低線量率放射線 / 放射線高感受性 / In Vitro Transformation / HTLVー1 / cDNAクローン / 下垂体由来増殖因子 / Mouse hepatoma / 発ガン過程 / Chemically defined medium / adaptation / 多発性骨髄腫 / signal transduction / chromosome / 腫瘍細胞株 / 癌発生率 / 無血清培地 / ラット下垂体細胞株 / gnome instability / 環境 / ラット乳腺上皮細胞株 / Reassessment of atomic bomb radiation dosimetry / N-myc / 前胃腫瘍p53変異 / Acute leukemia / BCR遺伝子 / 制御遺伝子 / Radiosensitivity / U3 / rpsL遺伝子 / 揺らぎ / Magnetic Field / Armitage-Dollモデル / Atomic bomb survivor / 遺伝毒性検定 / Mutation ; in vivo / 人体影響 / 免疫 / 適応応答 / マウス重症複合型免疫不全症 / in vivo selection assay / PCR法 / レトロウイルス / Mutagenicity test / 細胞・組織 / mutation / Individual difference / RAS oncogene / 肝がんp53変異 / 病理解析 / bcr gene / 神経成長因子 / 癌遺伝子 / ^252f中性子の生物影響 / 転写因子 / 原爆被爆生存者 / MVKモデル / DNA結合タンパク質 / マウス劣性遺伝病 / 逆転写 / スラロイドホルモン受容体 / 内在性 / oncogenesis / 標的理論 / 【^(252)Cf】中性子の生物影響 / ypsL / low dose and dose-rate / Oxidative DNA Damage / グルココルチコイド / 家系 / cell transformation / Autocrine growth factor / Rat pituitary cell line / DNAメチル化 / clastogenic activity / ゲノム / Multistage model / rpsL gene / 宇宙放射線の影響 / 地下空気環境 / MLV / 環境変異原 / 免疫不全症 / シャトルベクター / 多標的モデル / メチルコラントレン / 転移と糖蛋白質 / Human Health Effects / cancer / 慢性骨髄性白血症 / ras遺伝子 / rpsL / chromosome aberration / 大気中浮遊微粒子 / 被爆者及び動物における発癌 / 分子標的創薬 / 分子遺伝学 / Cell cycle regulation / Mutation / multistep carcinogenesis / 健康調査 / Gene expression / インビトロ発癌 / 多段階発がん / チロシンキナーゼ / Age-dependency / 遺伝子損傷性ストレス / Myelodysplastic syndrome / アポトーシス / Chronic leukemia / 遺伝的不安定性伝説 / 脂肪前駆細胞 / 可移植性 / 酸化ストレス / Underground Air Pollution / コホートデータ解析 / 放射線感受性 / トランスフォ-ム遺伝子 / Advanced Living Environment / 骨髄増殖症候群 / CAP / Genetic instability / がん状態 / 精子細胞期 / environmental factors / Chronic myelocytic leukemia / Signal transduction / 細胞 / Lincar model / RBE of neutrons / 多段階モデル / 自己増殖因子 / 突然変異誘発 / Rat mammary epithelial cell line / Apoptsis / 制がん / ヘテロサイクリックアミン / 放射線誘発がん / DNA damage / homologus recombination / 被爆線量 / Myeloproliferative disorders / Risk assessment of neutronsin man / 癌転移 / 分化誘導 / 重点領域研究 / 乳腺由来増殖因子 / genomic instability / 放射線発ガン / 乳腺間充織細胞 / がん / 転写制御因子 / 年齢依存性 / 原爆被爆者の死因 / 宇宙環境放射線 / 宇宙環境 / 骨髄異形成性症候群 / 発がん数理モデル / 放射線治療生物学 / 磁場の遺伝的影響 / Glucocorticoid / LOH / BPV / ヒトにおける中性D1C子のリスク評価 / タンパク質リン酸化 / Philadelphia chromosome / 細胞接着分子 / モロニーMLV / CDNAクローン / 数理モデル / 癌治療 / DNA修復 / Dose-response relation / エンハンサー / gene / がん突然変異 / 胚幹細胞 / マウス肝癌 / RNAアプタマー / 遺伝性疾患 / 中性子のRBE / 肉腫・c-myc増幅 / 発がんリスク評価 / DNA修復欠損 / Genotoxicity test / 幹細胞 / scid / ポリADPーリボース / RNA工学 / 放射線誘発肝癌 / コホート研究 / Carcinogenesis / 慢性白血病 / 遺伝的影響 / Pc-1 / トランスアクチベーション / Dose-response / 原爆放射線量再評価 / Mutagen / 突然変異検定 / レドックス制御 / 中性子のRBE、TLD測定 / 遺伝的不安定性仮説 / RBE / 低線量放射線 / 地下生活環境 / U5 RNA / 内在化 / Radiation / TLD dosimetry / immune system / Philaselphia染色体 / Transgenic mouse / DNA資料 / low dose and low dose-rate radiation / 罹患率データ / Carcinogenicity in man and animals / 遺伝 / Oxidative stress / 無血清培養 / トラシスフォ-ム遺伝子 / 個体差 / 遺伝学 / 細胞バンク / 近距離被爆者 / atomic bomb survivors Less

Molecular targeted drug discovery for cancer cell radiosensitization using RNA aptamars
- Principal Investigator
  
  KURIMASA Akihiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Radiation science
  Living organism molecular science
- Research Institution
  Tottori University
がん研究の資材有効保存と利用に関する研究
- Principal Investigator
  
  清木元治
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Role of p53 in radiation induced genomic instabilityPrincipal Investigator
- Principal Investigator
  
  NIWA Ohtsura
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  National Institute of Radiological Sciences
  Kyoto University
Genetic and Epigenetic Dysregulation in Cancer
- Principal Investigator
  
  NODA Tetsuo
- Project Period (FY)
  2004 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
  Tohoku University
分裂酵母を用いた放射線誘発ゲノム不安定性の研究Principal Investigator
- Principal Investigator
  
  丹羽太貫
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kyoto University
p53 dependent S checkpoint in early mouse embryos and radiation induction of genomic instabilityPrincipal Investigator
- Principal Investigator
  
  NIWA Ohtsura
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Kyoto University
Mathematical Models for Carcinogenesis Based on the Evidence of Molecular Biology and Its Application to Data Analysis
- Principal Investigator
  
  OHTAKI Megu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Statistical science
- Research Institution
  HIROSHIMA UNIVERSITY
DT40細胞と酵母を用いた放射線誘発ゲノム不安定性の研究Principal Investigator
- Principal Investigator
  
  丹羽太貫
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Kyoto University
Mechanisms of cell responses by low dose and low dose-rate irradiation
- Principal Investigator
  
  OHNISHI Takeo
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Nara Medical University
GENOMIC INSTABILITY AND MOLECULAR MECHANISM OF DELAYED MUTAION IN Fl MICE BORN TO IRRADIATED SPERMATOZOAPrincipal Investigator
- Principal Investigator
  
  NIWA Ohtsura
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  KYOTO UNIVERSITY
Mechanisms of oncogenesis and anti-oncogenesis
- Principal Investigator
  
  SASAZUKI Takehiko
- Project Period (FY)
  1999 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  International Medical Center of Japan
  Kyushu University
Mathematical modeling in carcinogenesis to elucidate the mechanism of radiation-induced cancer
- Principal Investigator
  
  KAI Michiaki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Oita University of Nursing and Health Sciences
放射線発がんにおける遺伝的不安定性の役割とその分子機構Principal Investigator
- Principal Investigator
  
  丹羽太貫
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
Genetic analysis for cancer risk estimation of low-dose radiation exposure.
- Principal Investigator
  
  KAMIYA Kenji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  HIROSHIMA UNIVERSITY
Mechanisum of radiation induction of genomic instabilityPrincipal Investigator
- Principal Investigator
  
  NIWA Ohtsura
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  KYOTO UNIVERSITY
マウス肉腫細胞における遺伝的不安定性の解析Principal Investigator
- Principal Investigator
  
  丹羽太貫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hiroshima University
放射線影響研究の新しい展開
- Principal Investigator
  
  佐々木正夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Kyoto University
免疫不全症およびDNA修復欠損の原因遺伝子HYRCの特性と単離
- Principal Investigator
  
  KOMATSU Kenshi
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hiroshima University
マウスミニサテライト遺伝子座を用いた放射線誘発生殖細胞突然変異のモニター系の開発
- Principal Investigator
  
  神谷研二
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Hiroshima University
Studies of Somatic Mutation Frequencies and Spectra with a Sensitive and Efficient Detection Method by Using Transgenic Mice.
- Principal Investigator
  
  GONDO Yoichi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  遺伝
- Research Institution
  TOKAI UNIVERSITY
Methematical Modeling of Carcinogenesis
- Principal Investigator
  
  OHTAKI Megu
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Statistical science
- Research Institution
  HIROSHIMA UNIVERSITY
胚性腫瘍と胚幹細胞の成立と分化の機構Principal Investigator
- Principal Investigator
  
  丹羽太貫
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hiroshima University
Gene regulation of radiation response
- Principal Investigator
  
  SASAKI Masao
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  KYOTO UNIVERSITY
c-myc遺伝子プロモーターに結合する転写因子ZF-5の細胞増殖抑制効果Principal Investigator
- Principal Investigator
  
  丹羽太貫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hiroshima University
マウス初期胚特異的転写抑制因子ELPの機能と発現制御機構の解析Principal Investigator
- Principal Investigator
  
  丹羽太貫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hiroshima University
マウスミニサテライト遺伝子座における放射線誘発生殖細胞突然変異の解析
- Principal Investigator
  
  神谷研二
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Hiroshima University
"Man-Earth System : A scientific approach to realize human society in harmony with the Earth"-Future Advanced Living Environment and Its Possible Effects on Humans-
- Principal Investigator
  
  IKENAGA Mitsuo
- Project Period (FY)
  1993 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
胚性腫瘍と胚幹細胞の成立と分化の機構
- Principal Investigator
  
  近藤寿人
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Nagoya University
放射線応答の制御機構に関する研究
- Principal Investigator
  
  SASAKI Masao
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  放射線5生物学
- Research Institution
  Kyoto University
乳腺の脂肪前駆細胞が分泌する乳腺増殖因子の分離・精製
- Principal Investigator
  
  KAMIYA Kenji
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Hiroshima University
胚性腫瘍細胞におけるがん状態と分化の遺伝子支配
- Principal Investigator
  
  近藤寿人
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Nagoya University
癌転移に関与する細胞側要因の解析Principal Investigator
- Principal Investigator
  
  丹羽太貫
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hiroshima University
実験動物がんのがん遺伝子
- Principal Investigator
  
  長尾美奈子
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
胚性腫瘍細胞におけるがん状態と分化の遺伝子支配
- Principal Investigator
  
  近藤寿人
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Nagoya University
癌転移に関与する細胞側要因の解析
- Principal Investigator
  
  YOKORO Kenjiro
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hiroshima University
小分子RNAによる癌化機構に関する解析
- Principal Investigator
  
  濱田勝友
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hiroshima University
胚性腫瘍細胞におけるがん状態と分化の遺伝子支配
- Principal Investigator
  
  近藤寿人
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Nagoya University
Molecular and cytogenetic studies on hematopoietic cells in heavily exposed A-bomb survivors
- Principal Investigator
  
  KAMADA Nanao
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  放射線5生物学
- Research Institution
  Hiroshima University
Purification and Characterization of New Mammary Cell Growth Factor from Rat Pituitary Tumors : Preliminary Report.
- Principal Investigator
  
  KAMIYA Kenji
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Hiroshima University
白血病ウイルスの増殖・内在化・遺伝子発現
- Principal Investigator
  
  吉倉廣
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
胚性腫瘍細胞の分化素過程の分子的解析
- Principal Investigator
  
  村松喬
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kagoshima University
Cytogenetic and molecular studies on mechanism of acquisition of malignant progression in chronic hematopoietic neoplasia
- Principal Investigator
  
  OGUMA Nobuo
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  HIROSHIMA UNIVERSITY
胚性腫瘍細胞の分化素過程の分子的解析
- Principal Investigator
  
  村松喬
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kagoshima University
高発がん変異の遺伝機構
- Principal Investigator
  
  野村大成
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
白血病ウイルスの増殖・内在化・遺伝子発現
- Principal Investigator
  
  吉倉広
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
胚性腫瘍細胞の分化素過程の分子的解析
- Principal Investigator
  
  村松喬
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kagoshima University
高発がん変異の遺伝機構
- Principal Investigator
  
  野村大成
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
白血病ウイルスの増殖・内在化・遺伝子発現
- Principal Investigator
  
  吉倉廣
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
高発がん変異の遺伝機構
- Principal Investigator
  
  野村大成
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
RNA腫瘍ウイルスの内因化機構に関する研究Principal Investigator
- Principal Investigator
  
  丹羽太貫
- Project Period (FY)
  1985
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hiroshima University
Experimental studies on the dosimetry and biological effects of neutrons
- Principal Investigator
  
  YOKORO Kenjiro
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  放射線5生物学
- Research Institution
  HIROSHIMA UNIVERSITY
Analysis of cell transformation by small molecular weight RNA.Principal Investigator
- Principal Investigator
  
  NIWA Ohtsura, 瀬山敏雄, 濱田勝友
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  HIROSHIMA UNIVERSITY

All 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation Book

[Book] Radiation Research2007
- Author(s)
  Nakano M, Kodama Y, Ohtaki K, Niwa O, Nakamura N
- Publisher
  Chromosome aberrations do not persist in the lymphocytes or bone marrow cells of mice irradiated in utero or soon after birth.(in press)
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Radiation induction of delayed recombination in Schizosaccharomyces pombe2008
- Author(s)
  丹羽太貫, 他
- Journal Title
  
  DNA Repair (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Radiation induction of delayed recombination in Schizosaccharomyces pombe2008
- Author(s)
  丹羽太貫, 他
- Journal Title
  
  DNA Repair (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Radiation induction of delayed recombination in Schizosaccharomyces pombe.2008
- Author(s)
  J. Takeda, 0. Niwa, et. al. (total 6, last)
- Journal Title
  
  DNA Repair (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16059101
[Journal Article] p21 provides stage specific DNA damage control to preimplantation embryos.2007
- Author(s)
  Adiga SK, Toyoshima M, Shiraishi K, Shimura T, Takeda J, tage M, Nagai H, Kumar P, Niwa O.
- Journal Title
  
  Oncogene 26(42)
  
  Pages : 6141-419
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Delayed and stage specific phosphorylation of H2AX during preimplantation development of gamma-irradiated mouse embryos. Reproduction2007
- Author(s)
  丹羽太貫, 他
- Journal Title
  
  Reproduction 133
  
  Pages : 415-422
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Pattern of Allelic Loss and Inactivation of Cadherin 1 and 5 Genes in Mammary Carcinomas Arising in p53^<+/-> Mice2007
- Author(s)
  丹羽太貫, 他
- Journal Title
  
  Journal of Radiation Research (Tokyo) 48
  
  Pages : 143-152
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Chromosome aberrations do not persist in the lymphocytes or bone marrow cells of mice irradiated in utero or soon after birth.2007
- Author(s)
  丹羽太貫, 他
- Journal Title
  
  Radiation Research 67
  
  Pages : 693-702
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Characterization of novel murine anti-CD20 monoclonal antibodies and their comparison to 2B8 and c2B8 (rituximab).2007
- Author(s)
  丹羽太貫, 他
- Journal Title
  
  International Journal of Oncology. 31
  
  Pages : 29-40
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Delayed and stage specific phosphorylation of H2AX during preimplantation development of gamma-irradiated mouse embryos.2007
- Author(s)
  Adiga Sk, Toyoshima M, Shimura T., Takeda J, Uematsu N, Niwa O.
- Journal Title
  
  Reproduction 133(2)
  
  Pages : 415-422
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type 1-MMP-dependent tumor growth in mice2007
- Author(s)
  Taniwaki, K., Seiki, M. (他10名)
- Journal Title
  
  Cancer Research 67
  
  Pages : 4311-4319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012003
[Journal Article] p21 provides stage specific DNA damage control to preimplantation embryos2007
- Author(s)
  Adiga SK, Toyoshima M, Shiraishi K, Shimura T, Takeda J, Taga M, Nagai H, Kumar P, Niwa O
- Journal Title
  
  Oncogene (in press)
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Delayed and stage specific phosphorylation of H2AX during preimplantation development of gamma-irradiated mouse embryos2007
- Author(s)
  Adiga SK, Toyoshima M, Shimura T., Takeda J, Uematsu N, Niwa O
- Journal Title
  
  Reproduction 133
  
  Pages : 415-422
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] p21 provides stage specific DNA damage control to preimplantation embryos2007
- Author(s)
  丹羽太貫, 他
- Journal Title
  
  Oncogene 26
  
  Pages : 6141-6419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Pattern of Allelic Loss and Inactivation of Cadherin-1 and 5 Genes in Mammary Carcinomas Arising in p3^+/-^ Mice.2007
- Author(s)
  Umesako S, Iiga S, Takahashi M, Imura K, Mori N, Hong D-P, Song C-W, Niwa O, Okumoto M.
- Journal Title
  
  J Radiat Res(Tokyo) 48(2)
  
  Pages : 143-152
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Pattern of Allelic Loss and Inactivation of Cadherin 1 and 5 Genes in Mammary Carcinomas Arising in p53^<+/-> Mice2007
- Author(s)
  丹羽太貫, 他
- Journal Title
  
  Jouranl of Radiation Research(Tokyo) 48
  
  Pages : 143-152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] p21 provides stage specific DNA damage control to preimplantation embryos.2007
- Author(s)
  S.K.Adiga, O.Niwa et al.(total 9, last)
- Journal Title
  
  Oncogene 2007 (in press)
- Data Source
  KAKENHI-PROJECT-16059101
[Journal Article] Chromosome aberrations do not persist in the lymphocytes or bone marrow cells of mice irradiated in utero or soon after birth.2007
- Author(s)
  Nakano M, Kodama Y, Ohtaki K, Niwa O, Nakamura N.
- Journal Title
  
  Radiat. Res. 67(6)
  
  Pages : 693-702
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Haracterization of novel murine anti-CD20 momoclonal antibodies nad their comparison to 2B8 and C2B8.2007
- Author(s)
  Nishida M, Usuda S, Okabe M, Miyakoda H, Komatsu M, Hanaoka H, Teshigawara K, Niwa O.
- Journal Title
  
  Int. J. Oncol. 31(1)
  
  Pages : 29-40
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] p21 provides stage specific DNA damage control to preimplantation embryos2007
- Author(s)
  丹羽太貫, 他
- Journal Title
  
  Oncogene 26
  
  Pages : 6141-419
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Chromosome aberrations do not persist in the lymphocytes or bone marrow cells of mice irradiated in utero or soon after birth.2007
- Author(s)
  丹羽太貫, 他
- Journal Title
  
  Radiation Research 67
  
  Pages : 693-702
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Delayed and stage specific phosphoylation of H2AX during preimplantaion development of gamma-irradiated mouse embryos.Reproduction2007
- Author(s)
  丹羽太貫, 他
- Journal Title
  
  Reproduction 133
  
  Pages : 415-422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Characterization of novel murine anti-CD20 monoclonal antibodies and their comparison to 2B8 and c2B8(rituximab).2007
- Author(s)
  丹羽太貫, 他
- Journal Title
  
  International Journal of Oncology. 31
  
  Pages : 29-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Indirect mechanisms of genomic instability and the biological significance of mutations at tandem repeat loci.2006
- Author(s)
  Niwa O.
- Journal Title
  
  Mutation Research 598(1-2)
  
  Pages : 61-72
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Radiation carcinogenesis in mouse thymic lymphomas.2006
- Author(s)
  Kominami R, Niwa O
- Journal Title
  
  Cancer Science 97
  
  Pages : 575-581
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Radiation induction of dynamic mutation and transecncrational effects2006
- Author(s)
  Niwa, O.
- Journal Title
  
  J. Radiat. Res. 47
  
  Pages : 25-30
- Data Source
  KAKENHI-PROJECT-17012003
[Journal Article] Suppression of replication fork progression in low dose specific p53 dependent S-phase DNA damage checkpoint.2006
- Author(s)
  Shimura T, Toyoshima M, Adiga SK, Kunoh T, Nagai H, Shimizu N, Inoue M, Niwa O
- Journal Title
  
  Oncogene 25
  
  Pages : 5921-5932
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Suppression of replication fork progression in low dose specific p53 dependent S-phase DNA damage checkpoint.2006
- Author(s)
  Shimura T, Toyoshima M, Adiga SK, Kunoh T, Nagai H, Shimizu N, Inoue M, Niwa O.
- Journal Title
  
  Oncogene 25(44)
  
  Pages : 5921-5932
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Suppression of replication fork progression in low dose specific p53 dependent S-phase DNA damage checkpoint.2006
- Author(s)
  Shimura T, Toyoshima M, Adiga SK, Kunoh T, Nagai H, Shimizu N, Inoue M, Niwa O.
- Journal Title
  
  Oncogene in press
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Indirect mechanisms of genomic instability and the biological significance of mutations at tandem repeat loci2006
- Author(s)
  Niwa, O.
- Journal Title
  
  Mutation Research 598
  
  Pages : 61-72
- Data Source
  KAKENHI-PROJECT-17012003
[Journal Article] Indirect mechanisms of genomic instability and the biological significance of mutations at tandem repeat loci.2006
- Author(s)
  Niwa O.
- Journal Title
  
  Mutation Research in press
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Radiation induction of dynamic mutation and transgeneratinal effects.2006
- Author(s)
  Niwa O.
- Journal Title
  
  J. Radiat. Res. 47
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Radiation induction of dynamic mutation and transgenerational effects.2006
- Author(s)
  Niwa O
- Journal Title
  
  Journal of Radiation Research 47, Supl B
  
  Pages : 25-30
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Indirect mechanisms of genomic instability and the biological significance of mutations at tandem repeat loci.2006
- Author(s)
  Niwa O
- Journal Title
  
  Mutation Research 598
  
  Pages : 61-72
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Comparison of properies of spontaneous and radiation induced mouse thymic lymphomas : Role of Trp53 and radiation.2005
- Author(s)
  Kubota T, Yoshikai Y, Tamura Y, Mishima Y, Aoyagi Y, Niwa O, Kominami R.
- Journal Title
  
  Radiation Research 163
  
  Pages : 159-164
- Data Source
  KAKENHI-PROJECT-14380123
[Journal Article] Transcription independent suppression of DNA synthesis by p53 in sperm irradiated mouse zygotes.2005
- Author(s)
  Niwa.O.(他7名)
- Journal Title
  
  Oncogene Feb.14
- Data Source
  KAKENHI-PROJECT-16059101
[Journal Article] Transcription independent suppression of DNA synthesis by p53 in sperm irradiated mouse zygotes.2005
- Author(s)
  M.Toyoshima, O.Niwa et al.(total 8, last)
- Journal Title
  
  Oncogene 24(20)
  
  Pages : 3229-3235
- Data Source
  KAKENHI-PROJECT-16059101
[Journal Article] Transcription independent suppression of DNA synthesis by p53 in sperm irradiated mouse zygotes.2005
- Author(s)
  Toyoshima M, Shimura T, Adiga SK, Taga M, Shiraishi K, Inoue M, Yuan Z-M, Niwa O.
- Journal Title
  
  Oncogene 24
  
  Pages : 3229-3235
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Transcription independent suppression of DNA synthesis by p53 in sperm irradiated mouse zygotes.2005
- Author(s)
  Toyoshima M, Shimura T, Adiga SK, Taga M, Shiraishi K, Inoue M, Yuan Z-M, Niwa O.
- Journal Title
  
  Oncogene 24
  
  Pages : 3229-3235
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208067
[Journal Article] RERF : the monument and the crisis2004
- Author(s)
  Niwa O
- Journal Title
  
  Radiat.Res. 162
  
  Pages : 105-105
- Data Source
  KAKENHI-PROJECT-15651017
[Journal Article] Generation of multipotent stem cells from postnatal mouse testis.2004
- Author(s)
  Kanatsu-Shinohara M, Inoue K, Lee J, Yoshimoto M, Ogonuki N, Miki H, Kato T, Baba S, Kazuki Y, Toyokuni S, Toyoshima M, Niwa O, Oshimura M, Heike T, Ishino F, Nakahata T, Ogura A, Shinohara, T.
- Journal Title
  
  Cell 119
  
  Pages : 1001-1012
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208067
[Journal Article] Predisposition to mouse thymic lymphomas in response to ionizing radiation depends on variant alleles encoding metal-responsive transcription factor-1(Mtf-1).2004
- Author(s)
  Tamura Y, Maruyama M, Mishima Y, Fujisawa H, Obata M, Kodama Y, Yoshikai Y, Aoyagi Y, Niwa O, Schaffner W, Kominami R.
- Journal Title
  
  Oncogene 24
  
  Pages : 399-406
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208067
[Journal Article] Generation of multipotent stem cells from postnatal mouse testis.2004
- Author(s)
  Niwa.O.(他17名)
- Journal Title
  
  Cell 119(7)
  
  Pages : 1001-1012
- Data Source
  KAKENHI-PROJECT-16059101
[Journal Article] RERF : the monument and the crisis2004
- Author(s)
  Niwa O
- Journal Title
  
  Radiat.Res. 162
  
  Pages : 105-105
- Data Source
  KAKENHI-PROJECT-14208067
[Journal Article] Induced genomic instability in irradiated germ cells and in the offspring ; reconciling discrepancies among the human and animal studies.2003
- Author(s)
  Niwa, O.
- Journal Title
  
  Oncogene 22
  
  Pages : 7078-7086
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208067
[Journal Article] Induced genomic instability in irradiated germ cells and in the offspring ; reconciling discrepancies among the human and animal studies.2003
- Author(s)
  Niwa, O
- Journal Title
  
  Oncogene 22
  
  Pages : 7078-7086
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14208067
[Journal Article] Bcll1b is required for differentiation and survival of ab T lymphocytes.2003
- Author(s)
  Wakabayashi, Y., J.Inoue, J.Sakata, Y.Takahashi, A.Matsuki, H.Kosugi-Okano, Y.Miyazawa, Y.Saito, H.Watanabe, Y.Mixhims, O.Niwa, R.Kominami
- Journal Title
  
  Nature Immunol. 4
  
  Pages : 533-539
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208067
[Journal Article] p53 dependent S phase damage checkpoint and pronuclear crosstalk in mouse zygotes with X-irradiated sperm.2002
- Author(s)
  Shimura, T., M.Inoue, M.Taga, K.Shiraishi, N.Uematsu, N.Takei, Z.Yuan, O.Niwa
- Journal Title
  
  Mol.Cell.Biol. 22
  
  Pages : 2220-2228
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14208067
[Journal Article] Radiation induction of delayed recombination in S. pombe.
- Author(s)
  Takada J, uematsu N, Shiraishi S, Toyoshima M, Matsumoto T, Niwa O.
- Journal Title
  
  DNA Repair (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201014
[Journal Article] Suppression of replication fork progression in low dose specific p53 dependent S-phase DNA damage checkpoint
- Author(s)
  Shimura, T., Niwa, T.他7名
- Journal Title
  
  Oncogene (in press)
- Data Source
  KAKENHI-PROJECT-17012003
[Presentation] がん放射線治療の展開と生物影響の基礎研究2009
- Author(s)
  丹羽太貫
- Organizer
  茨城大学理学部量子サイエンスフォーラム公開シンポジウム第2回Quantum Medicine研究会
- Place of Presentation
  茨城大学理学部(水戸市文京2-1-1)
- Year and Date
  2009-01-31
- Data Source
  KAKENHI-PROJECT-20200039
[Presentation] Science and values in radiation protection2008
- Author(s)
  丹羽太貫
- Organizer
  Workshop on Low Dose Radiation
- Place of Presentation
  Helsinki, Finland
- Year and Date
  2008-01-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201014
[Presentation] Science and values in radiation protection2008
- Author(s)
  丹羽太貫
- Organizer
  Workshop on Low Dose Radiation
- Place of Presentation
  Helsinki,Finland
- Year and Date
  2008-01-15
- Data Source
  KAKENHI-PROJECT-17201014
[Presentation] p53 dependency of untargeted and delayed recombination in mice born to sperm irradiated mice2007
- Author(s)
  丹羽太貫
- Organizer
  Gordon Research Conference
- Place of Presentation
  Oxford, England
- Year and Date
  2007-08-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201014
[Presentation] Early molecular events in preimplantation stage mouse embryos born to irradiated sperm2007
- Author(s)
  丹羽太貫
- Organizer
  International Conference of Radiation Research
- Place of Presentation
  San Francisco, USA
- Year and Date
  2007-07-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201014
[Presentation] p53 dependency of untargeted and delayed recombination in mice born to spermirradiated mice2007
- Author(s)
  丹羽太貫
- Organizer
  Gordon Research Conference
- Place of Presentation
  Oxford,England
- Data Source
  KAKENHI-PROJECT-17201014
[Presentation] Early molecular events in preimplantation stage mouse embryos born to irradiated sperm2007
- Author(s)
  丹羽太貫
- Organizer
  International Conference of Radiation Research
- Place of Presentation
  San Francisco,USA
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-17201014

1. 村松喬 (00030891)

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2. 近藤寿人 (70127083)

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Niwa Ohtsura 丹羽 太貫

NIWA Ohtsura 丹羽 太貫

丹羽 大貫 ニワ オオツラ

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Role of p53 in radiation induced genomic instabilityPrincipal Investigator

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分裂酵母を用いた放射線誘発ゲノム不安定性の研究Principal Investigator

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p53 dependent S checkpoint in early mouse embryos and radiation induction of genomic instabilityPrincipal Investigator

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DT40細胞と酵母を用いた放射線誘発ゲノム不安定性の研究Principal Investigator

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GENOMIC INSTABILITY AND MOLECULAR MECHANISM OF DELAYED MUTAION IN Fl MICE BORN TO IRRADIATED SPERMATOZOAPrincipal Investigator

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放射線発がんにおける遺伝的不安定性の役割とその分子機構Principal Investigator

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Niwa Ohtsura 丹羽太貫

NIWA Ohtsura 丹羽太貫

丹羽大貫ニワオオツラ