NORIMURA Toshiyuki 法村俊之

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法村俊之

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Researcher Number	20039530
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Affiliation (based on the past Project Information) *help	1990 – 2009: University of Occupational and Environmental Health, Professor, 医学部, 教授 1987: 産業医科大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator 環境影響評価(含放射線生物学) / Risk sciences of radiation/Chemicals Except Principal Investigator 環境影響評価(含放射線生物学) / Risk sciences of radiation/Chemicals / Radiation science / Radiation science
Keywords	Principal Investigator 放射線 / 超伝導磁石 / 磁場 / ヒトTリンパ球 / p53 gene / アポトーシス / p53遺伝子 / p53ノックアウトマウス / 生物学的効果 / tissue repair … More / dose-rate dependence / 組織修復 / 線量率 / X-rays / apoptosis / 奇形 / 免疫機能 / 生体影響 / 突然変異 / 細胞増殖 / genomic instability / radiation / p53-dependent apoptosis / mutation / ゲノム不安定性 / p53-deficient mouse / malformation / p53 / p53ノックスとマウス / p53-deficient mice / teratogenesis / prenatal death / phenotypical anomalies / 催奇性障害 / 催奇性傷害 / 胎児死亡 / 子宮内被曝 / 催奇性 / マウス / 発生異常 / 年齢依存性 / 感受性分布 / 放射線感受性 / 放射線生物学 / 培養細胞 … More Except Principal Investigator p53 / アポトーシス / Fas / ガンマ線 / T細胞 / 化学療法 / 温熱療法 / radiation carcinogenesis / skin cancer / repetitive irradiation / Beta-irradiation / KO mouse / P53 gene / 放射線発がん / 皮膚がん / 反復照射 / ベータ線 / ノックアウトマウス / p53遺伝子 / gnome instability / mutation / cellcycle / apoptosis / adaptation / signal transduction / low dose and low dose-rate radiation / 遺伝的不安定性 / 突然変異誘発 / 細胞周期 / 適応 / 情報伝達 / 低線量・低線量率放射線 / time course / transgenic mouse / HITEC mouse / organ-specific / gamma-rays / Radiation-induced / New HITEC マウス / 経時変化 / トランスジェニックマウス / New HITECマウス / 臓器特異性 / 放射線誘発突然変異 / Apoptosis / T cell / thymus / spleen / gamma rays / gld mice / lpr mice / FAS / 1prマウス / 胸腺 / 脾臓 / gldマウス / lprマウス / Chemotherapy / Hyperthermia / Radiotherapy / Conventional Cancer Therapy / Chinese Herbal Medicine / Immunology / Biological Response Modifier / 普及型がん治療法 / 漢方薬エキス / 生物学的応答修飾剤 / 放射線療法 / 普及型がん治療 / 生物応答修飾剤 / 化学寮法 / 温熱寮法 / 放射線寮法 / 普及型がん治寮 / 漢方薬 / 免疫 / 生物応答性飾剤 / 膜輸送 / ヘム蛋白 / 血流 / フィブリン / イオン流 / 電場 / 磁場 / 放射線治療 / 高気圧酸素治療 / C3H / SCCIV / パクリタキセル / 低酸素細胞 / カルボプラチン / 高気圧酸素 / 癌 / ゲノム / マイクロアレイ / 放射線 / 発現制御 / 染色体異常 / 突然変異 / カロリー制限 / 温熱による放射線の増感 / 奇形 / p53欠失マウス / ナイミ-ヘン症候群 / 放射線感受性 / Ataxia telangiectasia遺伝子 / DNA依存性プロテインキナーゼ Less

Combination of hyperthermia and hyperbaric oxygen treatment to improve the antitumor efficacy of chemotherapy or radiotherapy
- Principal Investigator
  
  OHGURI Takayuki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  University of Occupational and Environmental Health, Japan
Molecular mechanisms for a suppressive effect of calorie restriction on cancer induction by radiation
- Principal Investigator
  
  ONO Tetsuya
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Tohoku University
Infulence of p53 on the induction of mouse skin tumors by repetitive beta-irradiation
- Principal Investigator
  
  OOTSUYAMA Akira
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  University of Occupational and Environmental Health, Japan
The role of p53 in protection of radiation mutagenesisPrincipal Investigator
- Principal Investigator
  
  NORIMURA Toshiyuki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  University of Occupational and Environmental Health, Japan
Mechanisms of cell responses by low dose and low dose-rate irradiation
- Principal Investigator
  
  OHNISHI Takeo
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Nara Medical University
Analysis of tissue-specific mutations induced by radiation in HITEC mice
- Principal Investigator
  
  OOTSUYAMA Akira
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  University of Occupational & Environmental Health
Biological defense mechanisms against teratogenic damage and the role of p53 genePrincipal Investigator
- Principal Investigator
  
  NORIMURA Toshiyuki
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  University of Occupational and Environmental Health
p53欠損マウスの胚発生に及ぼす4.7T定常磁場の影響Principal Investigator
- Principal Investigator
  
  法村俊之
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  University of Occupational and Environmental Health, Japan
放射線感受性予測の基礎研究
- Principal Investigator
  
  鈴木紀夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Relationship between retardation of auto immune disease
- Principal Investigator
  
  OOTSUYAMA Akira
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  University of Occupational and Environmental Health
マウス生体防御機構への4.7超強磁場の影響Principal Investigator
- Principal Investigator
  
  法村俊之
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  University of Occupational and Environmental Health, Japan
p53-dependent apoptosis suppresses radiation-induced teratogenesisPrincipal Investigator
- Principal Investigator
  
  NORIMURA Toshiyuki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  University of Occupational and Environmental Health
放射線に対するヒトTリンパ球の感受性分布とその年齢依存性Principal Investigator
- Principal Investigator
  
  法村俊之
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  University of Occupational and Environmental Health, Japan
哺乳類細胞への6.3T超強磁場の影響Principal Investigator
- Principal Investigator
  
  法村俊之
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  University of Occupational and Environmental Health, Japan
哺乳類細胞への6.3T超強磁場の影響Principal Investigator
- Principal Investigator
  
  法村俊之
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  University of Occupational and Environmental Health, Japan
哺乳類細胞への6.3T超強磁場の影響Principal Investigator
- Principal Investigator
  
  法村俊之
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  University of Occupational and Environmental Health, Japan
Study on Clinical Application of Chinese Herbal Medicine as A Biological Response Modifier
- Principal Investigator
  
  SUGAHARA Tsutomu
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B).
- Research Field
  
  Radiation science
- Research Institution
  Health Research Foundation
物理的環境(磁場, 電場)の生体影響
- Principal Investigator
  
  志賀健
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Ehime University

All 2009 2007 2006 2005 2003

All Journal Article Presentation

[Journal Article] Prolonged increase in T-cell receptor (TCR) variant fractions of spleen T lymphocytes in pregnant mice after gamma irradiation2007
- Author(s)
  Y. Igari, K. Igari, N. Kunugita, A. Ootsuyama, T. Norimura
- Journal Title
  
  Radiation Research 168(1)
  
  Pages: 81-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201011
[Journal Article] The delayed manifestation of T-cell receptor (TCR) variants in X-irradiated mice depends on Trp53 status.2006
- Author(s)
  Igari, K., Igari, Y., Okazaki, R., Kato, F., Ootsuyama, A., Norimura, T.
- Journal Title
  
  Radiation Research (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201013
[Journal Article] 体細胞における突然変異2006
- Author(s)
  法村俊之
- Journal Title
  
  エネルギー 39・3
  
  Pages: 62-63
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15201013
[Journal Article] Role of p53 gene in genetic instability induced by ionizing radiation.2005
- Author(s)
  Igari, K., Igari, Y., Kakihara, H., Kato, F., Ootsuyama, A., Norimura, T.
- Journal Title
  
  International Congress Series 1276
  
  Pages: 262-263
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201013
[Journal Article] Increased radiosensitivity of splenic T lymphocytes in pregnant mice.2005
- Author(s)
  Igari, Y., Igari, K., Kakihara, H., Kato, F., Ootsuyama, A., Norimura, T.
- Journal Title
  
  International Congress Series 1276
  
  Pages: 183-184
- NAID
  130005443068
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201013
[Journal Article] Radioadaptive response for protection against radiation-induced teratogenesis.2005
- Author(s)
  Okazaki, R., Ootsuyama, A., Norimura, T.
- Journal Title
  
  Radiation Research 163(3)
  
  Pages: 266-270
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201013
[Journal Article] Effect of exposure to low-dose rate radiation on autoimmune diseases of immunologically suppressed MRL/MpTn-gld/gld mice.2003
- Author(s)
  Ootsuyama, A., Okazaki, R., Norimura, T.
- Journal Title
  
  J.Radiation Research 44(3)
  
  Pages: 243-247
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201013
[Presentation] 温熱療法と高気圧酸素治療の2者併用によるカルボプラチンの増感効果-動物実験での検討2009
- Author(s)
  大栗隆行, 矢原勝哉, 文昇大, 山口晋作, 興梠征典, 柿原ひろ代, 法村俊之, 欅田尚樹, 今田肇, 成定宏之
- Organizer
  日本ハイパーサーミア学会第26回大会
- Place of Presentation
  千葉市
- Year and Date
  2009-09-12
- Data Source
  KAKENHI-PROJECT-20790915
[Presentation] 温熱療法と高気圧酸素治療の2者併用によるカルボプラチンの増感効果-動物実験での検討2009
- Author(s)
  大栗隆行, 矢原勝哉, 文昇大, 山口晋作, 興梠征典, 柿原ひろ代, 法村俊之, 欅田尚樹, 今田肇, 成定宏之
- Organizer
  第22回九州・山口地区ハイパーサーミア研究会
- Place of Presentation
  北九州市
- Year and Date
  2009-07-25
- Data Source
  KAKENHI-PROJECT-20790915

1. IMADA Hajime (50223326)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. KUNUGITA Naoki (90178020)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
3. OOTSUYAMA Akira (10194218)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
4. NOMOTO Satoshi (90258608)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. KATO Fumio (20309959)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
6. KOMATSU Kenshi (80124577)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. UEHARA Yoshihiko (30223499)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. ONO Tetsuya (00107509)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SHIMADA Yoshiya (10201550)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. OHGURI Takayuki (80469395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. YAHARA Katsuya (80441830)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. KOROGI Yukunori (60195691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. SUGAHARA Tsutomu (00025511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. YOSHIKAWA Toshiichi (90158410)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TAKAHASHI Masaji (00026931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NAKATSUGAWA Sigekazu (00180315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. GONDO Yoichi (40225678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. OHNISHI Takeo (60094554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. NIWA Ootsura (80093293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. UTSUMI Hiroshi (20025646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. WATANABE Masami (20111768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. FUJIKAWA Kazuo (90247958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 鈴木紀夫 (10010050)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 平岡真寛 (70173218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 佐々木正夫 (20013857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 小川恭弘 (90152397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 志賀健 (10028350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 松本伍良 (20001670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 東照正 (80116087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 宮本博司 (50088514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 伊達宗行 (80028076)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 土屋武彦 (60122850)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. MOON Seung dae

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
34. MUKOJIMA Tsuyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NORIMURA Toshiyuki 法村 俊之

法村 俊之

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The role of p53 in protection of radiation mutagenesisPrincipal Investigator

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Biological defense mechanisms against teratogenic damage and the role of p53 genePrincipal Investigator

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p53欠損マウスの胚発生に及ぼす4.7T定常磁場の影響Principal Investigator

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マウス生体防御機構への4.7超強磁場の影響Principal Investigator

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p53-dependent apoptosis suppresses radiation-induced teratogenesisPrincipal Investigator

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放射線に対するヒトTリンパ球の感受性分布とその年齢依存性Principal Investigator

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哺乳類細胞への6.3T超強磁場の影響Principal Investigator

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哺乳類細胞への6.3T超強磁場の影響Principal Investigator

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NORIMURA Toshiyuki 法村俊之

法村俊之