MURAMATSU Takashi 村松喬

Researcher Number	00030891
Affiliation (based on the past Project Information) *help	2004 – 2008: Aichi Gakuin University, Faculty of Psychological and Physical Sciences, Department of Health Science, Professor, 心身科学部, 教授 2002 – 2004: Graduate School of Medicine, Professor, 大学院・医学系研究科, 教授 2001 – 2004: 名古屋大学, 大学院・医学研究科, 教授 2000 – 2001: 名古屋大学, 医学研究科, 教授 1993 – 2000: Nagoya University School of Medicine, Dept.Biochemistry, Professor, 医学部, 教授 … More 1993: 名古屋大学, 医学部・第一生化学教室, 教授 1986 – 1993: 鹿児島大学, 医学部, 教授 1986: 鹿大, 医学部, 教授 1985: 鹿児島大学, 医, 教授 Less
Review Section/Research Field	Principal Investigator 物質生物化学 / General medical chemistry / Structural biochemistry / General medical chemistry / Pathological medical chemistry / Functional biochemistry / Biological Sciences / Pathological medical chemistry Except Principal Investigator General surgery / Digestive surgery … More / Developmental biology / Pathological medical chemistry / Surgical dentistry / Plastic surgery / Obstetrics and gynecology / Psychiatric science / Functional biochemistry / Circulatory organs internal medicine / General medical chemistry / Biological Sciences / General surgery / Circulatory organs internal medicine Less
Keywords	Principal Investigator ミッドカイン / レチノイン酸 / 糖タンパク質 / 成長因子 / 胚性腫瘍細胞 / テラトカルシノーマ / ヘパリン / セレクチン / がん転移 / ムチン … More / Midkine / 糖脂質 / 糖転移酵素 / ガングリオシド / プロテオグリカン / ヘパラン硫酸 / シンデカン / スルホトランスフェラーゼ / 細胞分化 / 分化誘導 / コンドロイチン硫酸 / スルフォトランスフェラーゼ / L-セレクチン / ニューログリカンC / トランスジェニックマウス / EC細胞 / TPA / DNA結合タンパク質 / cDNAクローン / マウス発生 / 転写制御 / アルツハイマー病 / 神経突起伸長 / がん / midkine / NMR / 好中球 / N-アセチルグルコサミン / リンパ球ホーミング / ノックアウトマウス / 胚発生 / 脱がん / フコシル抗原 / シアリルルウィスX / フコシルトランスフェラーゼ / N-アセチルグルコサミントランスフェラーゼ / 成人T細胞性白血病 / N-アセチルガラクトサミントランスフェラーゼ / 合成ペプチド / ベイシジン / 免疫グロブリンスーパーファミリー / 精子形成 / リンパ管浸潤 / ヘパリン結合性成長因子 / シナプス / 海馬 / アグリン / カルレチニン / アストロサイト / プロテインホスファターゼ / 異種抗原 / N-アセチルガラクトサミニルトランスフェラーゼ / 糖鎖シグナル / フコシダーゼ / 糖鎖硫酸化 / シグナル入力 / 受容体 / receptor-like protein tyrosine phosphatase-ζ / インテグリン / anaplastic leukemia lymphoma kinase / 膜内複合体 / オリゴデンドロサイト前駆体細胞 / チロシンキナーゼ / チロシンホスファターゼ / 神経突起 / 免疫沈降 / 接着因子 / 糖抗原 / キメラマウス / CDNAクローン / 分化 / 免疫グロブリン遺伝子スーパーファミリー / ポリADPーリボース / モロニー白血病ウイルス / シグナル伝達 / 分化因子 / in situハイブリダイゼンション / cDNAクローニング / 細胞接着 / レクチン / 糖鎖欠損 / 統鎖生物学 / プロチオグリカン / 発生分化 / 統転移酵素 / マクロファ-ジ / エンドサイト-シス / 癌転移 / ガラクト-ス転移酵素 / エンドグリコシダ-ゼ / Glycoprotein / Glycolipid / Ganglioside / Cell adhesion / Glycosyltransferase / Lectin / Mucin / Carbohydrate deficience / MK遺伝子 / 神経栄養因子 / レチノイン酸レセプター / ウィルムス腫瘍 / MK / ヒト癌 / MK gene / Growth factor / neurotrophic factor / retinoic acid receptor / Syndecan / Arzheimer disease / Wilms'tumor / 組織修復 / レセプター / ヘパリン硫酸 / プラズミノーゲン活性化酵素 / heparin / growth factor / tissue repair / receptor / heparan sulfate / neurite outgrowth / cancer / シナプス形成 / リューマチ / カルシュウム動員 / サイトカイン / 増殖分化因子 / 神経分化 / プラスミノーゲン活性化酵素 / Hepari / Synaps / Cancer / Neutrophil / Rheumatoid arthritic / Calcium mobilization / 酵素抗体法 / 腫瘍マーカー / スプライシング異常 / リンパ節転移 / 骨折 / 遺伝子治療 / 炎症 / 肺癌 / 腎透析 / Enzyme-linked immunoassay / Tumor marker / Splicing / Lymphnode metastasis / Bone fracture / Gene therapy / Inflammation / 血液凝固 / オリゴ糖合成 / L-セレクチンリガンド / 癌性糖鎖 / ルウィスX / 糖鎖抗原 / 糖鎖生物学 / 糖鎖識別 / sulfotransferase / N-acetylglucosamine / L-selectin / Blood coagulation / Oligosaccharide synchesis / Glycoproteins / スルホトランスフェラー / 神経発生 / 聴覚 / 脳損傷 / ケラタン硫酸 / 神経前駆体細胞 / プレイオトロフィン / N-アセチルグルコミン / 神経幹細胞 / IGnT / パイエル板 / ポリ-N-アセチルラクトサミン / I抗原 / N-アセチルガラクトサミン / 硫酸化 / Sulfotransferse / Proteoglycan / Neurogenesis / Auditory deficits / Brain injury / Keratan sulfate / Knockout mice / 抗がん剤 / 腎臓毒性 / 血管内皮 / アンチセンスオリゴDNA / リウマチ / 新生内膜形成 / 炎症性細胞 / 癒着 / マクロファージ / Anti-cancer drug / renal toxicity / knockout mice / neutrophils / tumor metastasis / endothelial cells / antisense oligo DNA … More Except Principal Investigator ミッドカイン / 糖鎖遺伝子 / 糖転移酵素 / 癌転移 / 細胞接着分子 / 転移と糖蛋白質 / 胚性腫瘍 / シアリダーゼ / Midkine / 糖タンパク質 / ノックアウトマウス / カドヘリン / ES細胞 / 遺伝子トラップ / ガングリオシド / 発現制御 / 転移 / 胚幹細胞 / 糖鎖 / アクチビン / サイトカイン / 異種移植 / 異種抗原 / 補体不活化因子 / トランスジェニック動物 / 胚性腫瘍細胞 / 転写因子 / 癌遺伝子 / ZPーO / テラト-マ / オクタマ-配列 / 増殖因子 / 遺伝子破壊 / 細胞分化 / 細胞外マトリックス / 糖鎖分解酵素 / N-myc / Oct-3 / ミドカイン / ベイシジン / 癌細胞 / トランスジェニックマウス / マウス / TGF-β / BMP / 形質転換 / 成長因子 / ヌードマウス / 遺伝子治療 / midkine / 神経栄養因子 / がん転移 / ガラクトシルトランスフェラーゼ / 遺伝子制御 / トランスジェニックブタ / ノックアウト動物 / α1.3GT / α1.2FT / Transplantation, Heterologous / Animals, Transgenic / Complement Inactivators / Antigens, Heterophile / Galactosylransferases / Fucosyltransferases / コンドロイチン硫酸 / 糖脂質 / プロテオグリカン / glycoprotein / proteoglycan / glycosyltransferase / ミッドカイン(MK) / LRP / LRP6 / 細胞膜 / siRNA / レクチン / モノクローナル抗体 / 幹細胞 / がん状態 / 分化 / エンハンサー / 制御遺伝子 / チロシンキナーゼ / GPクロ / テラトカルシノーマ / 発生・形態形成 / A5分子 / レチノイン酸 / ホメオボックス / 肥満細胞 / シロイヌナズナ / 色素上皮 / N型カドヘリン / エンビジン / マクロファ-ジ / 顔面形態形成 / ラミニン / 卵管因子 / 免疫抑制物質 / 糖糖分解酵素 / 細胞接着因子 / homing receptor / 運動因子 / src関連遺伝子 / アクチン / fos遺伝子 / 遺伝的不安定性 / テラトカルシノ-マ / 卵管上皮 / マウス全胚培養 / LGL / 組織化学 / プロトオンコジ-ン / cDNAクローニング / 転写調節 / 細胞接着蛋白 / 糖鎖リガンド / 癌浸潤 / ポリオーマウイルス / スラロイドホルモン受容体 / 神経成長因子 / 転写制御因子 / 無血清培養 / 癌細胞接着 / 糖鎖合成酵素 / 硫酸化糖鎖 / シアリルルイス-X / フコース転移酵素 / 酵素cDNA / LTR / PEBP2 / AML / 細胞導入 / 遺伝子クローニング / α1-6フコシルトランスフェラーゼ / シアリルルイスX / GnT-III / シアル酸転移酵素 / Gal転移酵素 / T細胞受容体 / 標的遺伝子組換え / ジーンターゲッティング / 中枢神経系 / 免疫系 / 形態形成 / ras / ドーパミン受容体 / 突然変異 / グルタミン酸受容体 / H-ras / セロトニン受容体 / p53 / 相周遺伝子組換え / 始原生殖細胞 / メダカ / ゼブラフィッシュ / ニワトリ / レロトウイルスベクター / 相同遺伝子組換え / レトロウイルスベクター / 細胞認識分子 / 細胞成長因子 / ホメオティック遺伝子 / 神経形成 / 四肢形成 / 細胞分化転換 / 器官形成 / フォリスタチン / 生殖細胞 / 細胞系譜 / 遺伝子発現 / 神経誘導 / 内胚葉分化 / 胴尾部構造 / ミドカイニン / ビテロゲニン / ビテロジェニン / 筋分化 / 胚軸形成 / 神経分化 / 胚誘導 / T遺伝子 / 背腹軸 / 極細胞 / ミトコンドリア / 発生・分化 / ELP / NIH3T3細胞 / 酵素免疫測定法 / 組織形成 / がん発生 / がん進展 / ヘパリン / トランスグルタミナーゼ / ヘパリン結合性成長因子 / アフリカツメガエル / Smad / シグナル伝達系 / 糖鎖生物学 / 糖鎖工学 / クローニング / 培養唾液腺細胞 / アミラーゼ / 細胞培養 / 唾液腺細胞 / TGF-βスーパーファミリー / 前癌状態 / プレイオトロフィン / 受容体 / スプライシングバリアント / 熱傷モデル / 表皮細胞 / 線維芽細胞 / 免疫グリブリンスーパーファミリー / 精子形成 / 無精子症 / 統合失調症 / 海馬 / 発癌遺伝子 / 転移と血小板凝集能 / 転移と活性化マクロファージ / 胚付腫瘍細胞 / 細胞接着 / 種タンパク質 / CDNAクローン / 糖鎖構造 / 糖鎖プロセシング / 糖鎖抗原性 / マンナン結合タンパク質 / 癌移伝子 / 転移と血小板凝集活性 / 活性化マクロファージ / GP70:ZP-0;Macrophage;TTK-1;カドヘリン;in vitro implantation;テラトカルシノーマ / フコシルトランスフェラーゼ / フコシルトランスジェラーゼ / コンドロイチン-6-硫酸 / スルフォトランスフェラーゼ / 遺伝子ノックアウト / N-アセチルグルコサミン / ストローマ細胞 / 第9染色体 / FISH / コンドロイチン6-スルフォトランスフェラーゼ / chondroitin 6-sulfate / sulfotransferase / gene knockout / N-acetylglucosamine / 複合糖質 / 糖鎖リモデリング / sugar chain / glycoconjugate / sugar remodeling / glyco-gene / glycolipid / 動脈硬化 / 炎症 / 分子生物学 / 新生内膜増殖 / PTN / atherosclerosis / chemotaxis / growth substances / inflammation / knockout mice / 神経変性疾患 / 悪性腫瘍 / RET遺伝子 / Dorfin遺伝子 / 糖脂質糖鎖 / 癌の浸潤 / 糖鎖合成酵素遺伝子 / Src遺伝子 / 浸潤・転移 / Neurodegenerative disease / Malignant tumor / RET gene / Dorfin gene / Ganglioside / Cancer invasion / Transgenic mouse / LDL受容体ファミリー / 過硫酸化 / インテグリン / プロテインシークエンス / シャペロン / chondroitinsulfate / LDL interein receptor family / oversulfation / integrin / 生体調節 / シグナル / ノックアウト / グライコミクス / 分子複合体 / ミクロドメイン / 機能調節 / glycosylation / glycolinid / signal / Knolout / bioreyulation / 自家静脈グラフト / 内膜肥厚 / 血管内膜肥厚 / Vein graft / intimal hyperplasia / gene therapy / 心筋虚血再灌流障害 / アポトーシス / MKノックアウトマウス / ミッドカイン (MK) / 心筋虚血再灌流傷害 / myocardial injury / apoptosis / MK^<- / -> mice / 消化器癌 / 膜糖蛋白 / 二次元電気泳動 / レクチン染色 / レクチンアフィニティクロマトグラフィ / レクチンアフィニティクロマトグラフィー / Gastroenterological cancer / Metastasis / Nude mioe / Glycoprotein / Two-dimensional gel electrophoresis / Lectin statning / 基底膜 / マトリゲル / invasionーMTTassay / 浸潤 / 血行性転移 / モノクロ-ナル抗体 / 転移抑制 / Invasion Assay / 再構成基底膜 / MTT assay / 細胞膜成分 / 内皮細胞 / basement membrane / MATRIGEL / invasion-MTT assay / metastasis / invasion Less

Composition and mode of action of the midkine receptorPrincipal Investigator
- Principal Investigator
  
  MURAMATSU Takashi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Aichi Gakuin University
Development of therapy for malignant tumors and inflammatory diseases employing midkine as a molecular targetPrincipal Investigator
- Principal Investigator
  
  MURAMATSU Takashi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Aichi Gakuin University
  Nagoya University
The New Strategy of Gene Therapy for the Patients with Pheripheral Arterial Disease
- Principal Investigator
  
  KOMORI Kimihiro
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Nagoya University
Midkine plays a protective role against cardiac ischemia/reperfusion injury through a reduction of apoptotic reaction
- Principal Investigator
  
  HORIBA Mitsuru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Nagoya University
ミッドカイン欠損による海馬発達障害と精神分裂病の生物学的脆弱性との関連
- Principal Investigator
  
  清水栄司
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  Chiba University
Function regulation of proteins and molecular complexes with glycosylation.
- Principal Investigator
  
  FURUKAWA Koichi
- Project Period (FY)
  2002 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Recognition of sulfated hexosamine upon construction of the nervous systemPrincipal Investigator
- Principal Investigator
  
  MURAMATSU Takashi
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Aichi Gakuin University
  Nagoya University
Clarification of the receptor complex for midkine
- Principal Investigator
  
  MURAMATSU Hisako
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
Biological significance of N-acetylglucosamine 6-sulfationPrincipal Investigator
- Principal Investigator
  
  MURAMATSU Takashi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Nagoya University
がん発生・進展に重要なミッドカインの組織保護能と細胞内シグナル伝達
- Principal Investigator
  
  門松健治
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nagoya University
糖鎖シグナルによる細胞間コミュニケーションの制御Principal Investigator
- Principal Investigator
  
  村松喬
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nagoya University
皮膚の創傷治癒および器官形成におけるミッドカインの役割
- Principal Investigator
  
  長谷川隆
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Nagoya University
モデルマウスを用いた無精子症の遺伝子治療と精子生成過程の分子レベルでの解析
- Principal Investigator
  
  門松健治
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nagoya University
Sugar remodeling and cellular communication
- Principal Investigator
  
  TANIGUICHI Naoyuki
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
EFFECTS OF MIDKINE ON NEOINTIMA FORMATION IN A RESTENOSIS MODEL
- Principal Investigator
  
  HIRAKI Makoto
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  NAGOYA UNIVERSITY
Molecular Medicine of Neurodegenerative Disease and Malignant Tumor
- Principal Investigator
  
  TAKAHASHI Masahide
- Project Period (FY)
  1998 – 2002
- Research Category
  
  Grant-in-Aid for COE Research
- Research Institution
  Nagoya University
転移関連糖鎖を担うタンパク質のがんの浸潤、転移における役割とその作用機構Principal Investigator
- Principal Investigator
  
  村松喬
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
がん進展におけるミッドカインの役割および変異型MKの機能解析
- Principal Investigator
  
  門松健治
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
新しいヘパリン結合性成長分化因子ミッドカインの神経可塑性における役割Principal Investigator
- Principal Investigator
  
  村松喬
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
糖鎖デザインと細胞機能ネットワーク
- Principal Investigator
  
  谷口直之
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
培養唾液腺細胞を用いた唾液腺の増殖に関する基礎的研究
- Principal Investigator
  
  上田実
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Nagoya University
Application of midkine to diagnosis and treatment of tumors and growth of blood stem cells.Principal Investigator
- Principal Investigator
  
  MURAMATSU Takashi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nagoya University
Functional Analysis of chondroitin sulfate by knockout technique
- Principal Investigator
  
  MURAMATSU Hisako
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Nagoya University
標的遺伝子組換えによる突然変異体の作成とその生体機能の研究
- Principal Investigator
  
  勝木元也
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
  Kyushu University
がんの進展・転移に関与する糖鎖情報Principal Investigator
- Principal Investigator
  
  村松喬
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
がんの発生と進展におけるミッドカイン作用機構の解明
- Principal Investigator
  
  門松健治
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
遺伝子制御による異種移植の基礎的研究
- Principal Investigator
  
  TAKAGI Hiroshi
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Nagoya University
Research on xenotransplantation using genetic engineering
- Principal Investigator
  
  TAKAGI Hiroshi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  Nagoya University
Growth factor midkine : Biological significance, action mechanism, tissue repairing activity and relationship with diseases.Principal Investigator
- Principal Investigator
  
  MURAMATSU Takashi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
Transgenic pigs as organ donors in xenotransplantation
- Principal Investigator
  
  TAKAGI Hiroshi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  Nagoya University
がんの進展・転移に関与する糖鎖情報Principal Investigator
- Principal Investigator
  
  村松喬
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
がん化およびがん進展におけるミッドカインの役割
- Principal Investigator
  
  KADOMATSU Kenji
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
TGF-βスーパーファミリーによる組織形成機構をめぐる研究動向の調査
- Principal Investigator
  
  井出宏之
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Developmental biology
- Research Institution
  Tohoku University
がんの進展・転移に関与する糖鎖情報Principal Investigator
- Principal Investigator
  
  村松喬
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
胚性腫瘍と胚幹細胞の成立と分化の機構
- Principal Investigator
  
  丹羽太貫
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hiroshima University
Receptor structure and inhibition of midkine, a growth factor controled by retinoic acidPrincipal Investigator
- Principal Investigator
  
  MURAMATSU Takashi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Nagoya University
糖鎖の細胞認識と癌の進展,特性に関する研究
- Principal Investigator
  
  牧田章
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
胚性腫瘍と胚幹細胞の成立と分化の機構
- Principal Investigator
  
  近藤寿人
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
糖鎖遺伝子の特異性
- Principal Investigator
  
  谷口直之
- Project Period (FY)
  1993 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
ES細胞を用いた未知遺伝子の検索
- Principal Investigator
  
  山村研一
- Project Period (FY)
  1993 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
形態形成の調節機構-器官の形成と再生を制御する分子機構
- Principal Investigator
  
  藤澤肇
- Project Period (FY)
  1993 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
形態形成の調節機構-初期発生を制御する分子機構
- Principal Investigator
  
  浅島誠
- Project Period (FY)
  1993 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
糖鎖の細胞認識と癌の進展、特性の研究
- Principal Investigator
  
  牧田章
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
胚性腫瘍と胚幹細胞の成立と分化の機構
- Principal Investigator
  
  近藤寿人
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Nagoya University
Studies on a new growth factor under the control of retinoic acid, midkine (MK)Principal Investigator
- Principal Investigator
  
  MURAMATSU Takashi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  物質生物化学
- Research Institution
  Nagoya University School of Medicine
  Kagoshima University
胚性腫瘍細胞におけるがん状態と分化の遺伝子支配
- Principal Investigator
  
  近藤寿人
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Nagoya University
癌転移に関与する細胞側要因の解析
- Principal Investigator
  
  丹羽太貫
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hiroshima University
着床と胎盤形成の分子機構
- Principal Investigator
  
  森崇英
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
ガングリオシド糖鎖遺伝子と発現制御
- Principal Investigator
  
  鈴木明身
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
New Development in glycobiologyPrincipal Investigator
- Principal Investigator
  
  MURAMATSU Takashi
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  物質生物化学
- Research Institution
  Nagoya University School of Medicine
  Kagoshima University
胚性腫瘍細胞におけるがん状態と分化の遺伝子支配
- Principal Investigator
  
  近藤寿人
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Nagoya University
癌転移に関与する細胞側要因の解析
- Principal Investigator
  
  横路謙次郎
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hiroshima University
着床と胎盤形成の分子機構
- Principal Investigator
  
  森崇英
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
ガングリオシド糖鎖遺伝子と発現制御
- Principal Investigator
  
  SUZUKI Akemi
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
ガングリオシド糖鎖遺伝子と発現制御
- Principal Investigator
  
  鈴木明身
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
胚性腫瘍細胞におけるがん状態と分化の遺伝子支配
- Principal Investigator
  
  近藤寿人
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Nagoya University
癌転移に関与する細胞側要因の解析
- Principal Investigator
  
  横路謙次郎
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hiroshima University
レチノイン酸による分化脱がん時に初期応答する遺伝子群の解析Principal Investigator
- Principal Investigator
  
  村松喬
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kagoshima University
着床と胎盤形成の分子機構
- Principal Investigator
  
  森崇英
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
高次体制の形成・再生の制御とその因子
- Principal Investigator
  
  竹市雅俊
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
胚性腫瘍細胞の分化素過程の分子的解析Principal Investigator
- Principal Investigator
  
  村松喬
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kagoshima University
テラトカルシノーマの分化方向決定に関連する遺伝子の転写制御と機能Principal Investigator
- Principal Investigator
  
  村松喬
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kagoshima University
着床と胎盤形成の分子機構
- Principal Investigator
  
  森崇英
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Studies for Control of Metastasis Using Monoclonal Antibodies to Components of Blood-borne Metastatic Cancer Cells Surface
- Principal Investigator
  
  SHIMAZU Hisaaki
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kagoshima University
癌転移に関する基礎的研究
- Principal Investigator
  
  横路謙次郎
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hiroshima University
胚性腫瘍細胞の分化素過程の分子的解析Principal Investigator
- Principal Investigator
  
  村松喬
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kagoshima University
テラトカルシノーマの分化方向決定に関連する遺伝子の転写制御と機能Principal Investigator
- Principal Investigator
  
  村松喬
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kagoshima University
癌転移に関する基礎的研究
- Principal Investigator
  
  横路謙次郎
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hiroshima University
胚性腫瘍細胞の分化素過程の分子的解析Principal Investigator
- Principal Investigator
  
  村松喬
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kagoshima University
胚性腫瘍細胞の基質への接着に関与する細胞膜糖タンパク質のCDNAクローニング
- Principal Investigator
  
  OZAWA Masayuki
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kagoshima University
糖鎖の結合とその修飾
- Principal Investigator
  
  池中徳治
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Osaka University
胚性腫瘍細胞の器官,個体構成能の分子的背景Principal Investigator
- Principal Investigator
  
  村松喬
- Project Period (FY)
  1985
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kagoshima University
Studies on mechanism and control of metastasis using the metastasizing tumor line of human gastroenterological cancer
- Principal Investigator
  
  SHIMAZU Hisaaki, 加治佐隆
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kagoshima University

All 2009 2008 2006 2005 2004 2003 Other

All Journal Article Presentation Patent

[Journal Article] Glycosaminoglycan-binding cytokines as tumor markers2008
- Author(s)
  Takashi Muramatsu, Hisako Muramatsu
- Journal Title
  
  Proteomics Vol 16
  
  Pages: 3350-3359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590291
[Journal Article] Glycosaminoglycan-binding cytokines as tumor markers2008
- Author(s)
  Takashi Muramatsu, Hisako Muramatsu
- Journal Title
  
  Proteomics 16
  
  Pages: 3350-3359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590291
[Journal Article] Female infertility in mice deficient in midkine and pleiotrophin, which form a distinct family of growth factors.2006
- Author(s)
  Muramatsu, H., et al.
- Journal Title
  
  Genes Cells 11
  
  Pages: 1405-1417
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14082202
[Journal Article] Female infertility in mice deficient in midkine and pleiotrophin, which form a distinct family of growth factors.2006
- Author(s)
  Muramatsu, H.et al.
- Journal Title
  
  Genes Cells 11
  
  Pages: 1405-1417
- Data Source
  KAKENHI-PROJECT-14082202
[Journal Article] Female infertility in mice deficient in midkine and pleiotrophin, which form a distinct family of growth factors2006
- Author(s)
  Muramatsu H, et al.
- Journal Title
  
  Genes Cells 11
  
  Pages: 1405-1417
- Data Source
  KAKENHI-PROJECT-14082101
[Journal Article] Female infertility in mice deficient in midkine and pleiotrophin, which form distinct family of growth factors2006
- Author(s)
  Muramatsu, H., et al.
- Journal Title
  
  Genes Cells 11
  
  Pages: 1405-1417
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082202
[Journal Article] Antisense Oligodeoxyribonucleotide as to the Growth Factor Midkine Suppresses Neointima Formation Induced by Balloon Injury Am.2005
- Author(s)
  Hayashi K, Kadomatsu K, Banno H, Takei Y, Komori K, Muramatsu T
- Journal Title
  
  J Physiol in press
- Data Source
  KAKENHI-PROJECT-15390375
[Journal Article] N-Acetylglucosamine-6-O-sulfotransferases 1 and 2 cooperatively control lymphocyte homing through L-selectin ligand biosynthesis in high endothelial venules2005
- Author(s)
  Kawashima H, Petryniak B, K, Kadomatsu K, Muramatsu T, et al.
- Journal Title
  
  Nat. Immunol. 6
  
  Pages: 1096-1104
- Data Source
  KAKENHI-PROJECT-14082101
[Journal Article] Morpholino antisense oligomer targeting human midkine : Its application for cancer therapy.2005
- Author(s)
  Takei Y., Kadomatsu K., Yuasa K., Sato W., Muramatsu T.
- Journal Title
  
  Int.J.Cancer 114
  
  Pages: 490-497
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390103
[Journal Article] Lack of the growth factor midkine enhances survival against cisplatin-induced renal damage2004
- Author(s)
  Kawai H., Sato W., Yuzawa Y., Kosugi T., Matsuo S., Takei Y., Kadomatsu K., Muramatsu T.
- Journal Title
  
  Am.J.Pathol. 165
  
  Pages: 1603-1612
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390103
[Journal Article] Midkine, a heparin-binding growth factor, is fundamentally involved in pathogenesis of rheumatoid arthritis.2004
- Author(s)
  Maruyama K., Muramatsu H., Ishiguro N., Muramatsu T.
- Journal Title
  
  Arthritis Rheum. 50
  
  Pages: 1420-1429
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390103
[Journal Article] α4β1- and α61-integrins are functional receptors for midkine, a heparin-binding growth factor2004
- Author(s)
  Muramatsu, H. et al.
- Journal Title
  
  J.Cell Sci. 117
  
  Pages: 5405-5415
- Data Source
  KAKENHI-PROJECT-14082202
[Journal Article] α4β1- and α61-integrins are functional receptors for midkine, a heparin-binding growth factor2004
- Author(s)
  Muramatsu, H., et al.
- Journal Title
  
  J. Cell Sci 111
  
  Pages: 5405-5415
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14082202
[Journal Article] Antisense oligodeoxy-ribonucleotide as to the growth factor midkine suppresses neointima formation induced by balloon injury.
- Author(s)
  Hayashi K., Banno H., Kadomatsu K., Takei Y., Komori K., Muramatsu T.
- Journal Title
  
  Am.J.Phyaiol.Heart Circ.Physiol. (in press.)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390103
[Journal Article] Midkine, a heparin-binding growth factor, produced by the host enhances metastasis of Lewis lung carcinoma cells.
- Author(s)
  Salama R.H., Muramatsu H., Zou P., Okayama M., Muramatsu T.
- Journal Title
  
  Cancer Lett. (in press.)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390103
[Journal Article] Glycosaminoglycan-binding cytokines as tumor markers
- Author(s)
  Muramatsu T, Muramatsu H
- Journal Title
  
  Proteomics (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590291
[Journal Article] Midkine antisense oligodeoxyribonucleotide inhibits renal damage induced by ischemic reperfusion.
- Author(s)
  Sato W., Takei Y., Yuzawa Y., Matsuo S., Kadomatsu K., Muramatsu T.
- Journal Title
  
  Kidney Int. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390103
[Patent] ミッドカインによる心筋障害予防および治療への応用2003
- Inventor(s)
  堀場充, 児玉逸雄, 門松健治, 村松喬
- Industrial Property Rights Holder
  堀場充, 児玉逸雄
- Industrial Property Number
  2003-343805
- Filing Date
  2003-08-29
- Acquisition Date
  2003-11-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590734
[Presentation] Midkine and pleiotrophin as molecular targets for cancer therapy2009
- Author(s)
  Takashi Muramatsu
- Organizer
  Clinical and Translational Research on Cancer : Glycomics Applications
- Place of Presentation
  Toba, Japan
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19590291
[Presentation] ミッドカインによるオリゴデンドロサイト前駆細胞CG-4細胞におけるニューログリカンCとインテグリンの膜受容体複合体形成2008
- Author(s)
  市原啓子, 村松喬
- Organizer
  第81回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19590291
[Presentation] ミッドカインによるオリゴデンドロサイト前駆体細胞CG-4におけるニューログリカンCとインテグリンの膜受容体複合体形成2008
- Author(s)
  市原啓子、村松喬
- Organizer
  第81回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19590291

1. KADOMATSU Kenji (80204519)

# of Collaborated Projects: 13 results

# of Collaborated Products: 5 results
2. MURAMATSU Hisako (50182134)

# of Collaborated Projects: 12 results

# of Collaborated Products: 11 results
3. 丹羽太貫 (80093293)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
4. 竹市雅俊 (00025454)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
5. 近藤寿人 (70127083)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
6. 秦順一 (90051614)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
7. KAWASAKI Toshisuke (50025706)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
8. SUZUKI Akemi (70134533)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
9. IRIMURA Tatsuro (80092146)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
10. 成松久 (40129581)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
11. 牧田章 (60004561)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
12. KNNAGI Reiji (80161389)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
13. TANIGUICHI Naoyuki (90002188)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
14. FURUKAWA Koichi (80211530)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
15. KUROSAWA Nobuyuki (50241253)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
16. 濱田博司 (00208589)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
17. 瀬戸山千秋 (60040250)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
18. 舘鄰 (30011711)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
19. SAITO Masaki (60012762)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
20. 横路謙次郎 (70034618)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
21. 森崇英 (90026865)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
22. 森庸厚 (40012760)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
23. TAKAGI Hiroshi (70154755)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
24. OKADA Hidechika (30160683)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
25. OGAWA Tomoya (30087572)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
26. 上田國寛 (00027070)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
27. 高見澤裕吉 (60009107)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
28. SHIMAZU Hisaaki (30010242)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
29. 山本雅 (40134621)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
30. 杉本芳一 (10179161)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
31. 谷口俊一郎 (60117166)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
32. 松原修一郎 (60199841)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
33. 黒岩厚 (20134611)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
34. 鈴木義之 (90010389)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
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MURAMATSU Takashi 村松 喬

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Composition and mode of action of the midkine receptorPrincipal Investigator

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Development of therapy for malignant tumors and inflammatory diseases employing midkine as a molecular targetPrincipal Investigator

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Recognition of sulfated hexosamine upon construction of the nervous systemPrincipal Investigator

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Biological significance of N-acetylglucosamine 6-sulfationPrincipal Investigator

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糖鎖シグナルによる細胞間コミュニケーションの制御Principal Investigator

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MURAMATSU Takashi 村松喬