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TANIGUCHI SHUN'ICHIRO  谷口 俊一郎

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TANIGUCHI Shun-ichiro  谷口 俊一郎

TANIGUCHI Shun'ichiro  谷口 俊一朗

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Researcher Number 60117166
Other IDs
Affiliation (Current) 2020: 信州大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help 2016 – 2019: 信州大学, 医学部, 特任教授
2014 – 2017: 信州大学, 学術研究院医学系, 教授
2008 – 2013: Shinshu University, 医学系研究科, 教授
2011: 信州大学, 大学院・医学系研究科, 教授
2007: Shinshu University, 大学院・医学系研究科, 教授 … More
2006: Shinshu Univ., Dept.of Molecular and An giology, Professor, 大学院医学研究科, 教授
2005: Shinshu University, School of Medicine, Professor, 医学部, 教授
2003 – 2005: 信州大学, 大学院・医学研究科, 教授
2003: 信州大学, 医学部付属加齢適応センター, 教授
1999 – 2002: 信州大学, 医学部, 教授
1998 – 1999: 信州大学, 医学部・附属加齢適応研究センター, 教授
1998: 信州大学, 医学部・加齢適応研究センター, 教授
1998: 信州大学, 医学部附属加齢適応研究センター, 教授
1997: 信州大学, 医学部付属加齢適応研究所, 教授
1995 – 1997: Sinshu University, School of Medicine Professor, 医学部, 教授
1996: 信州大学, 医学部・加齢適応センター, 教授
1994: 九州大学, 生体防御医学研究所・細胞学部門, 助教授
1988 – 1994: 九州大学, 生体防御医学研究所, 助教授
1992 – 1993: Kyushu Univ. Associate Prof., 生医研, 助教授
1991: 九州大学, 生体防御医学研究所・細胞学部門, 助教授
1990: 九州大学, 生医研, 助教授
1986 – 1988: 九州大学, 生体防御医学研究所, 助手
1987: 九州大学, 生体防御医学研究所・細胞学部門, 助教授
1986: 九大, 生体防医研, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Experimental pathology / Experimental pathology / Immunology / Dermatology / Drug development chemistry / Basic Section 47060:Clinical pharmacy-related
Except Principal Investigator
Biological Sciences / Environmental physiology (including Physical medicine and Nutritional physiology) / Obstetrics and gynecology … More / Environmental physiology (including Physical medicine and Nutritional physiology) / Circulatory organs internal medicine / Experimental pathology / General surgery / Orthopaedic surgery / Sports science / Thoracic surgery / Applied health science / Environmental physiology(including physical medicine and nutritional physiology) / Cardiovascular medicine / 広領域 / Conservative dentistry / Human genetics / Surgical dentistry / Obstetrics and gynecology / General medical chemistry / Pathological medical chemistry / Cell biology / Sports science / General anatomy (including histology/embryology) / General pharmacology Less
Keywords
Principal Investigator
ASC / アクチン / 転移 / 癌 / 炎症 / 細胞骨格 / 細胞死 / 浸潤能 / 新種アクチン / 遺伝子導入 … More / カルポニン / アポトーシス / カスペース1 / 自然免疫 / 浸潤 / 固形がん / ビフィズス菌 / 安全性 / DDS / サイトカイン / fos / 転移能 / 運動能 / アクチン関連蛋白質 / cDNA導入 / alphaアクチン / 悪性度 / fosー癌遺伝子 / 転移抑制 / βmアクチン / ビンキュリン / 細胞運動能 / vーfos癌遺伝子 / カルポニンh1 / 線維芽細胞 / 子宮筋肉腫細胞 / 増殖 / カルポニンhl / ノックアウトマウス / 線維化 / 加齢 / 形質転換 / カルポニン欠失 / 腹膜中皮細胞 / CN遺伝子導入 / 腹膜播種の遺伝子治療 / 癌抑制遺伝子 / メチレーション / 1L-1β / 腹膜播種 / 悪性形質抑制 / 中皮細胞 / 宿主 / アクチン細胞骨格 / 腫瘍血管 / 分子標的 / 卵巣癌 / 腫瘍 / 感染 / ピロリ菌 / エネルギー産生 / オートファジー / メチル化 / ATP / サイクリンD / 平滑筋細胞 / Inflammasome / innate immunity / cell death / cancer / fascin / IL-1beta / IFNbeta / Inflamasome / inflammasome / がん / 分子相互作用 / 細胞増殖制御 / 免疫監視機構 / 悪性化 / 細胞核蛋白 / fos癌遺伝子 / 癌転移 / フオス癌遺伝子 / B16黒色腫 / v-fos癌遺伝子 / 3y1細胞 / NK感受性 / ヒアルロン酸 / HAS1,2 / ヒト悪性黒色腫 / 免疫不全マウス / 移植実験 / 腫瘍形成 / モエシン / 合成酵素遺伝子HAS1、HAS2 / HAS1あるいはHAS2発現 / dormant state / 遺伝子ASC / HAS / 細胞運動性 / 造腫瘍性 / Hyaluronate / Has1,2 / human melanoma / nude mice / transplantation of tumor / tumor formation / moesin / 低酸素環境 / 遺伝子組み換え / 単鎖抗体 / HER2 / 抗腫瘍性分子DDS / 固形がん治療 / 低酸素 / 抗腫瘍性抗体 / 抗腫瘍性サイトカイン / 発現分泌系 / scFv / 炎症性サイトカイン / 固形がんの嫌気的環境 / 遺伝子組み替え / 抗腫瘍性物質 / 宿主免疫応答 / サイトカイン産生 / 黄色ブドウ球菌 / マクロファージ / 好中球 / TLR2,4 / 大腸菌 / 生物製剤 / がん治療 / 獲得免疫 / 抗がん分子 / デリバリー … More
Except Principal Investigator
アクチン / 癌転移 / カルポニン / ASC / actin / カドヘリン / 癌遺伝子 / 転移 / 浸潤 / 炎症 / 細胞骨格 / フィブロネクチン / 接着帯 / 細胞接着分子 / 転移と糖蛋白質 / ジーンターゲッティング / p53 / Transforming growth factor / mRNA / メタロプロテアーゼ / Ras / 発癌遺伝子 / 活性酸素 / MAPキナーゼ / インフラマソーム / 熱中症予防 / 生活習慣病 / 遺伝子修飾 / 細胞接着 / cancer / 卵巣癌 / calponin / デスモソーム / 浸潤転移 / 放射線治療 / 先行指標 / H-ras / Bone morphogenetic protein / 歯髄細胞 / 象牙芽細胞 / 修復象牙質 / 細胞培養 / 生活歯髄切断法 / トランスジェニックマウス / がん / マクロファージ / 血管新生 / 自然免疫 / NADPH oxidase / 情報伝達 / Nox1 / IL-18 / 暑熱耐性 / 運動トレーニング / スポーツ生理学 / 運動生理学 / インシュリン / IL-1β / 運動処方 / インターバル速歩 / メチル化 / がん転移 / cell adhesion / PDGF / PYRIN / calponin h1 / truncate / mutation / motility / 遺伝子治療 / ovarian cancer / gene therapy / scapinin / phactr / Src / 中間径フィラメント / Vーfos / がん悪性化 / メタロプロテア-ゼ / TIMP / NDPキナ-ゼ / βmアクチン / 細胞接着因子 / homing receptor / 運動因子 / src関連遺伝子 / fos遺伝子 / 遺伝的不安定性 / トランスジェニック / アルキル化剤 / キメラマウス / MNU / DMBA / 細胞外マトリックス分解酵素 / 92-kDa typeIV Collagenase / 72-kDa typeIV Collagenase / がん遺伝子 / がん抑制遺伝子 / 肉腫 / リンパ腫 / 局所制御率 / 発がん / ras / マウス / 突然変異 / がん関連遺伝子 / 癌 / マトリックスメタロプロテアーゼ / NM23 / がん浸潤・転移 / 細胞外マトリックス / マトリックス、メタロプロテアーゼ / 転移抑制遺伝子 / 胎盤形成 / 転移・浸潤 / 細胞外マトリックス分解 / 膜型メタロプロテアーゼ / 転移関連遺伝子 / 癌の進行 / 癌と宿主の相互作用 / マトリクス / 線維芽細胞 / 脈管系 / 転移のモデル / 癌の悪性化 / 腫瘍免疫 / 癌細胞の運動性 / 増殖因子 / 線維形成 / 微小環境 / 臓器特異性 / 細胞認識 / 液性因子 / 神経芽細胞腫 / ポリシアル酸 / ノックアウトマウス / 運動 / 血圧調節 / Moxl / GATA転写因子 / 腫瘍 / 動脈血圧 / 血圧反射 / ゲイン / 日内リズム / 覚醒レベル / 心血管 / シグナル伝達 / 心臓 / 虚血再灌流 / 骨髄細胞 / 動脈硬化 / 虚血性心疾患 / 炎症反応 / 大動脈瘤 / メカニカルストレス / リウマチ病学 / 関節炎 / IL-1beta / DBAマウス / コラーゲン誘発関節炎 / 体温調節能 / 血液量 / 中高年者 / 糖質・乳蛋白質 / 糖質・乳タンパク質 / 心移植 / 健康増進 / エピジェネティクス / NFkB遺伝子 / 運動介入実験 / エピジェネティックス / 抗炎症効果 / NFkB / 健康処方 / 遺伝子のメチル化 / 抗炎症 / スポーツ医科学 / 好気的運動能 / ALA / 分子血管病 / 分子血管学 / アンギオテンシン昇圧化学療法 / 強心剤 / 血管拡張剤 / 2経路化学療法 / シスプラチン / カルボコン / ミクロチュブール / ギャップ結合 / cDNA / 転移と血小板凝集活性 / チロシンキナーゼ / アンキリン / チロシンキナ-ゼ / デスモソ-ム / ラディキシン / アドヘレンス ジャンクション / cytoskeleton / cadherin / metastasis / tyrosine kinase / desmosome / 歯髄細胞培養 / ノーザンブロット / コラーゲンI型 / コラーゲンIII型 / オステオカルシン / アルカリフォスファターゼ / 象牙芽細胞誘導因子 / BONE Morphogenetic Protein / pulp cells / Odontoblasts / Reparative Dentin / Cell culture / Amputation / 大腸菌細胞株 / 遺伝子相同組み換え / K-ras遺伝子 / 大腸癌細胞株 / 血管内皮増殖因子 / K-ras / P53 / 相同組み換え / Colon cancer cell lines / homologous recombination / K-ras gene / 扁平上皮癌 / 増殖 / 浸潤移転 / ゲノム / Genomic Figer Print法 / Differential Display法 / 接着分子 / 造腫瘍能 / 遺伝子 / 同所性移植 / SQUAMOUS CELL CARCINOMA / GEOWTH / INVASION AND METASTASIS / GENOME / GENOMIC FINGER PRINT / DIFFERENTIAL DISPLAY / CELL SKELETONE / ADHESION MOLECULE / 平済筋型αアクチン / 細胞間相互作用 / 平滑筋型αアクチン / 血小板由来成長因子(PDGF) / Ovarian cancer / alpha-smooth muscle actin / Cell-cell interaction / アポトーシス / カスペース・1 / NF-KB / 炎症疾患 / Pyrin / Toll-like receptor / 感染 / 細胞死 / ガン / メチレーション / pyrin / CARD / apoptosis / caspase-1 / interleukine-1β / interleukine-18 / inflammation / innate immunity / カルポニンh1 / CH domain / Actin binding site / Calponin repeats / C terminal / actin安定性 / HT1080細胞 / truncates / 癌性腹膜炎 / peritonitis carcinomatosa / プロテインホスファターゼ-1 / 核構造 / 転写 / 脳 / 白血病 / 転写調節因子 / 転写調節 / 葉状仮足 / protein phosphatase-1 / nuclear structure / transcription / brain / 腹膜播種 / peritoneal dissemination / 乳製品摂取 / 生活習慣病予防 / 血漿量 / 要介護 / 熱中症 / 細胞運動 / 浸潤突起 Less
  • Research Projects

    (62 results)
  • Research Products

    (160 results)
  • Co-Researchers

    (137 People)
  •  ビフィズス菌を用いた固形がん選択的抗がん分子産生系の効率・安全性改善Principal InvestigatorOngoing

    • Principal Investigator
      谷口 俊一郎
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Shinshu University
  •  Development of system for in situ and continuous production of antitumor molecules.Principal Investigator

    • Principal Investigator
      Taniguchi Shunichiro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Shinshu University
  •  The preventive effects of exercise + milk product intake on lifestyle-related diseases and heat illness: the establishment of remote research system on a large population of subjects

    • Principal Investigator
      Nose Hiroshi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Sports science
    • Research Institution
      Shinshu University
  •  Clarification and application of a novel in vivo system which regulates interacting and homeostasis of organs

    • Principal Investigator
      SHINDO Takayuki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Shinshu University
  •  Analysis of the role of ASC as a regulator of metastatic phenotype

    • Principal Investigator
      FUJII Chifumi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including histology/embryology)
    • Research Institution
      Shinshu University
  •  A novel approach for cancer treatment based on homeostatic regulation of vascular system

    • Principal Investigator
      SHINDO Yuka
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Shinshu University
  •  Genome-wide analysis of epigenetic events induced by exercise prescription, and the significance in terms of preventive medicine

    • Principal Investigator
      HASHIMOTO Shigenari
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied health science
    • Research Institution
      Shinshu University
  •  Combined effects of exercise and 5-amino-levulinic acid intake on methylation of inflammatory genes

    • Principal Investigator
      NOSE Hiroshi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Environmental physiology(including physical medicine and nutritional physiology)
    • Research Institution
      Shinshu University
  •  The mechanisms for deterioration of thermoregulatory responses in older people and the counter measure against their heat illness

    • Principal Investigator
      NOSE Hiroshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Sports science
    • Research Institution
      Shinshu University
  •  Role of ASC in cardiac allograft rejection

    • Principal Investigator
      SETO Tatsuichiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Shinshu University
  •  Multiple functions of ASC that mainly regulates the formation of inflammasomePrincipal Investigator

    • Principal Investigator
      TANIGUCHI Shunichiro
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Shinshu University
  •  Modification of ASC genes by exercise training improves heat tolerance in middle aged and older people

    • Principal Investigator
      NOSE Hiroshi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Shinshu University
  •  Novel therapy for aortic aneurysms by targeting a mechanical stress sensor

    • Principal Investigator
      YOSHIMURA Koichi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Yamaguchi University
  •  ASC plays a role in the IL-1beta, IL-18 pathway of the immune response to type II collagen in collagen-induced arthritis

    • Principal Investigator
      TAKEOKA Michiko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Shinshu University
  •  自然免疫制御因子ASCによるATP代謝制御とオートファジーに伴う細胞死の制御Principal Investigator

    • Principal Investigator
      谷口 俊一郎
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Shinshu University
  •  Role of Inflammasomes as an initial sensor for cardiovascular stress

    • Principal Investigator
      TAKAHASHI Masafumi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
    • Research Field
      Circulatory organs internal medicine
      Experimental pathology
    • Research Institution
      Shinshu University
  •  Role of ASC, which regulates inflammation and cell death, in Helicobacter pylori infectionPrincipal Investigator

    • Principal Investigator
      TANIGUCHI Shun-ichiro
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Shinshu University
  •  Research for molecular mechanism and clinical application of calponin-gene therapy against Peritoneal dissemination of ovarian cancer

    • Principal Investigator
      KOBAYASHI Hiroaki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      KYUSHU UNIVERCITY
  •  細胞計画死と炎症シグナル制御に関与するASC/TMS1の発癌及び進展への関わりPrincipal Investigator

    • Principal Investigator
      谷口 俊一郎
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Shinshu University
  •  アクチン制御遺伝子カルポニンによる腹膜中皮細胞間接着能の亢進と癌の悪性形質抑制Principal Investigator

    • Principal Investigator
      谷口 俊一郎
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Shinshu University
  •  Association of Scapinin, a Protein Phosphatase-1-Binding Protein, with Nuclear Structure

    • Principal Investigator
      SAGARA Junji
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      Shinshu University
  •  活性酸素産生癌遺伝子Nox1を介したRas発癌機構の解析

    • Principal Investigator
      鎌田 徹
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Shinshu University
  •  カルポニン遺伝子欠損マウス行動量の日内リズム消滅機構の解明

    • Principal Investigator
      能勢 博
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Shinshu University
  •  A basic trial of gene therapy against peritoneal dissemination of ovarian cancer by calponin h1 gene transfer

    • Principal Investigator
      KOBAYASHI Hiroaki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      KYUSHU UNIVERSITY
  •  Ras発癌モデルを用いた活性酸素産生癌遺伝子Mox1の機能的解析

    • Principal Investigator
      鎌田 徹
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Shinshu University
  •  Identification of the region in calponin h1 that suppresses proliferation and motility of human fibrosarcoma

    • Principal Investigator
      TAKEOKA Michiko
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Shinshu University
  •  Ras発癌過程における活性酸素産生癌遺伝子Moxlの役割

    • Principal Investigator
      鎌田 徹
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Shinshu University
  •  アクチン関連蛋白質カルポニン等を分子標的とした癌の腹膜播種の検討Principal Investigator

    • Principal Investigator
      谷口 俊一郎
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Shinshu University
  •  カルポニン遺伝子欠損マウスの運動時血圧動揺機構の解析

    • Principal Investigator
      NOSE Hiroshi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Shinshu University
  •  Functional Study on a Novel Proapoptotic Protein of ASG

    • Principal Investigator
      SAGARA Junji
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      SHINSHU UNIVERSITY
  •  Hyaluronate production and the related molecules in human melanomaPrincipal Investigator

    • Principal Investigator
      TANIGUCHI Shun'ichiro
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Shinshu University
  •  神経芽細胞腫で発現するポリシアル酸の機能解析

    • Principal Investigator
      中山 淳
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Shinshu University
  •  カルポニン欠失マウスにおける過剰繊維化とその機序Principal Investigator

    • Principal Investigator
      谷口 俊一郎
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Shinshu University
  •  宿主を重視した転移の分子生物学

    • Principal Investigator
      入村 達郎
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  がん細胞の転移と浸潤の分子生物学

    • Principal Investigator
      清木 元治
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kanazawa University
  •  STUDY OF GENES WHICH REGULATE GROWTH OR METASTASIS IN HUMAN ORAL SQUAMOUS CELL CARCINOMA.

    • Principal Investigator
      MORIFUJI Masayo
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  Analysis for an ovarian cancer-derived factor which decreases the expression of alpha-smooth muscle actin in stromal cells

    • Principal Investigator
      KOBAYASHI Hiroaki
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kyushu University
  •  導入遺伝子に基づく個体発がんの研究

    • Principal Investigator
      権藤 洋一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokai University
      Kyushu University
  •  in vitro manipulation of genes relevant to oncogenesis

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Human genetics
    • Research Institution
      Medical Institute of Bioregulation, Kyushu University
  •  がん細胞の浸潤性獲得の分子機構

    • Principal Investigator
      清木 元治
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kanazawa University
  •  導入遺伝子に基づく個体発がんの研究

    • Principal Investigator
      勝木 元也
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  がんの放射線治療効果の先行指標の開発と統合

    • Principal Investigator
      増田 康治
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  がんの放射線治療効果の先行指標の開発と統合

    • Principal Investigator
      増田 康治
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  導入オンコジーンの体細胞突然変異によって起こる個体発癌の研究

    • Principal Investigator
      勝木 元也
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  生物学的覆髄剤の開発

    • Principal Investigator
      NAGASAWA Hisashi
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Institution
      Kyushu University
  •  Development of Bioactive Pulp Capping Agent

    • Principal Investigator
      NAGASAWA Hisashi
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      KYUSHU UNIVERSITY
  •  がん細胞の浸潤性獲得の分子機構

    • Principal Investigator
      清木 元治
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kanazawa University
  •  癌転移に関与する細胞側要因の解析

    • Principal Investigator
      丹羽 太貫
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hiroshima University
  •  癌の悪性度、特に転移能に関与する遺伝子の検索・同定とその生物学的機能解析Principal Investigator

    • Principal Investigator
      谷口 俊一郎
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  癌転移に関与する細胞側要因の解析

    • Principal Investigator
      横路 謙次郎
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hiroshima University
  •  癌の亜性度、特に転移能に関与する遺伝子の検索・同定とその生物学的機能解析Principal Investigator

    • Principal Investigator
      谷口 俊一郎
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  REGULATION OF CELL ADHESION BY CYTOSKELETON

    • Principal Investigator
      TSUKITA Shoichiro
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      広領域
    • Research Institution
      National Institute for Physiological Sciences
  •  がん細胞接着システムの制御機構

    • Principal Investigator
      竹市 雅俊
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  癌転移に関与する細胞側要因の解析

    • Principal Investigator
      横路 謙次郎
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hiroshima University
  •  癌の悪性度、特に転移能に関与する遺伝子の検索・同定とその生物学的機能解析Principal Investigator

    • Principal Investigator
      谷口 俊一郎
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  がん細胞接着システムの制御機構

    • Principal Investigator
      竹市 雅俊
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  癌転移に関する基礎的研究

    • Principal Investigator
      横路 謙次郎
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hiroshima University
  •  癌の悪性度、特に転移能に関与する遺伝子の検索・同定とその生物学的機能解析Principal Investigator

    • Principal Investigator
      谷口 俊一郎
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  がん細胞接着システムの制御機構

    • Principal Investigator
      竹市 雅俊
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  癌の悪性度(特に転移能)に関与する遺伝子の検索・同定とその生物学的機能解析Principal Investigator

    • Principal Investigator
      谷口 俊一郎
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  中和剤、昇圧剤その他薬剤組合せの工夫による癌化学療法効果増強

    • Principal Investigator
      馬場 恒男
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  癌の転移に関与する細胞骨格蛋白(アクチン)及び関連遺伝子の研究Principal Investigator

    • Principal Investigator
      谷口 俊一郎
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation Book Patent

  • [Book] Tumor-targeting therapy using gene-engineered anaerobic-nonpathogenic Bifidobacterium longum. Bacterial Therapy of Cancer Methods and Protocols edited by R. M. Hoffman2016

    • Author(s)
      Taniguchi S, Shimatani Y, Fujimori M
    • Total Pages
      186
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-15K08022
  • [Book] Methods Mol Biol.(edited by R.M. Hoffman 分担執筆)2016

    • Author(s)
      Taniguchi S, Shimatani Y, Fujimori M
    • Total Pages
      186
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-15K08022
  • [Book] 癌転移のメカニズムがよくわかる肝細胞のすべて(分担タイトル:細胞骨格に着目した癌転移の抑制-癌細胞と宿主の両面から-)2005

    • Author(s)
      谷口俊一郎(分担執筆:門田守人, 松浦成昭 編)
    • Total Pages
      379
    • Publisher
      永井書店
    • Data Source
      KAKENHI-PROJECT-16659100
  • [Journal Article] Cecal Tumorigenesis in Aryl Hydrocarbon Receptor-Deficient Mice Depends on Cecum-Specific Mitogen-Activated Protein Kinase Pathway Activation and Inflammation.2020

    • Author(s)
      Matoba H, Takamoto M, Fujii C, Kawakubo M, Kasuga E, Matsumura T, Natori T, Misawa K, Taniguchi S, Nakayama J.
    • Journal Title

      Am J Pathol.

      Volume: 190 Pages: 453-468

    • DOI

      10.1038/hr.2016.158

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06781
  • [Journal Article] G Protein Subunit β 1 Negatively Regulates NLRP3 Inflammasome Activation.2019

    • Author(s)
      Tomohiko Murakami, Lerdluck Ruengsinpinya, Eriko Nakamura,Yoshifumi Takahata, Kenji Hata, Hiroaki Okae,Shun’ichiro Taniguchi, Masafumi Takahashi and Riko Nishimura
    • Journal Title

      J Immunol

      Volume: 202 Pages: 1942-1947

    • DOI

      10.4049/jimmunol.1801388

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06781, KAKENHI-PROJECT-18K19640, KAKENHI-PROJECT-16H06393, KAKENHI-PROJECT-16H06270, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K09216, KAKENHI-PROJECT-19H03824
  • [Journal Article] IL-1β Plays an Important Role in Pressure Overload-Induced Atrial2019

    • Author(s)
      N Matsushita, N Ishida, M Takahashi, S Taniguchi, Y Iwakura, Y Sawa, M Hirose et al.
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 42 Pages: 543-546

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06781
  • [Journal Article] IL-1β Plays an Important Role in Pressure Overload-Induced Atrial Fibrillation in Mice2019

    • Author(s)
      Matsushita N, Ishida N, Ibi M, Saito M, Takahashi M, Taniguchi S, Iwakura Y, Morino Y, Taira E, Sawa Y, Hirose M
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 42 Issue: 4 Pages: 543-546

    • DOI

      10.1248/bpb.b18-00363

    • NAID

      130007622152

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-18K06781, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-19K11772, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
  • [Journal Article] The eNOS-NO pathway attenuates kidney dysfunction via suppression of inflammasome activation in aldosterone-induced renal injury model mice.2018

    • Author(s)
      Yuji Sogawa, Hajime Nagasu , Seiji Itano, Kengo Kidokoro, Shun’ichiro Taniguchi, Masafumi Takahashi, Hiroyuki Kadoya, Minoru Satoh, Tamaki Sasaki, Naoki Kashihara
    • Journal Title

      PLoS One

      Volume: 13

    • DOI

      10.1371/journal.pone.0203823

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06781, KAKENHI-PROJECT-18H02828
  • [Journal Article] Fascin1 suppresses RIG-I like receptor signaling and interferon-2018

    • Author(s)
      Tomio Matsumura Shigeaki Hida Masato Kitazawa Chifumi Fujii Akira Kobayashi Michiko Takeoka Shun'ichiro Taniguchi,and Shin-ichi Miyagawa
    • Journal Title

      J. Biol. Chem.

      Volume: 293 Pages: 6326-6336

    • DOI

      10.1074/jbc.m117.819201

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06781
  • [Journal Article] Potential Role of ASC, a Proapoptotic Protein, for Determining the Cisplatin Susceptibility of Lung Cancer Cells2018

    • Author(s)
      Takao Sakaizawa, Tomio Matsumura, Chifumi Fujii, Shigeaki Hida, Masayuki Toishi, Takayuki Shiina, Kazuo Yoshida, Kazutoshi Hamanaka, Ken-ichi Ito and Shun’ichiro Taniguchi
    • Journal Title

      Tohoku J. Exp. Med.

      Volume: 244 Issue: 2 Pages: 133-144

    • DOI

      10.1620/tjem.244.133

    • NAID

      130006356063

    • ISSN
      0040-8727, 1349-3329
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06781
  • [Journal Article] ASC Induces Apoptosis via Activation of Caspase-9 by Enhancing Gap Junction-Mediated Intercellular Communication.2017

    • Author(s)
      Kitazawa M, Hida S, Fujii C, Taniguchi S, Ito K, Matsumura T, Okada N, Sakaizawa T, Kobayashi A, Takeoka M, and Miyagawa SI
    • Journal Title

      PLoS One

      Volume: 12

    • DOI

      10.1371/journal.pone.0169340

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460272, KAKENHI-PROJECT-15K08022
  • [Journal Article] The endothelial adrenomedullin-RAMP2 system regulates vascular integrity and suppresses tumor metastasis.2017

    • Author(s)
      Tanaka M, Koyama T, Sakurai T Igarashi K, Shindo T, et al.
    • Journal Title

      Cardiovasc Res.

      Volume: 111 Pages: 398-409

    • DOI

      10.1093/cvr/cvw166

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16H06841, KAKENHI-PROJECT-26293183, KAKENHI-PROJECT-26460337, KAKENHI-PROJECT-16K08545, KAKENHI-PROJECT-16H00651, KAKENHI-PROJECT-16H00679
  • [Journal Article] Effects of milk product intake on thigh muscle strength and NFKB gene methylation during home-based interval walking training in older women: a randomized controlled study2017

    • Author(s)
      Masuki S, Nishida K, Hashimoto S, Morikawa M, Takasugi S, Nagata M, Taniguchi S, Rokutan K, and Nose H
    • Journal Title

      PLoS ONE

      Volume: 12

    • DOI

      10.1371/journal.pone.0176757

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H01830, KAKENHI-PROJECT-15H04680
  • [Journal Article] In situ delivery and production system of trastuzumab scFv with Bifidobacterium.2017

    • Author(s)
      Kikuchi Takeshi、Shimizu Hitomi、Akiyama Yasuto、Taniguchi Shun'ichiro
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 493 Pages: 306-312

    • DOI

      10.1016/j.bbrc.2017.09.026

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07209, KAKENHI-PROJECT-15K08022
  • [Journal Article] The endothelial adrenomedullin-RAMP2 system regulates vascular integrity and suppresses tumour metastasis.2016

    • Author(s)
      Tanaka M, Koyama T, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, LiuT, Xian X, Imai A, Zhai L, Hirabayashi K, Owa S, Yamauchi A, Igarashi K, Taniguchi S, Shindo T.
    • Journal Title

      Cardiovasc Res.

      Volume: 111 Pages: 398-409

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08022
  • [Journal Article] Novel role of ASC as a regulator of metastatic phenotype2016

    • Author(s)
      Okada N1, Fujii C1,2, Matsumura T, Kitazawa M, Okuyama R, Taniguchi S, and Hida S (1: Contributed equally, 2: Corresponding author)
    • Journal Title

      Cancer Med.

      Volume: 5 Pages: 2487-2500

    • DOI

      10.1002/cam4.800

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460272, KAKENHI-PROJECT-26461686, KAKENHI-PROJECT-15K08022
  • [Journal Article] Excess aldosterone is a critical danger signal for inflammasome activation in the development of renal fibrosis in mice.2015

    • Author(s)
      Kadoya H, Satoh M, Sasaki T, Taniguchi S, Takahashi M, Kashihara N.
    • Journal Title

      The FASEB Journal

      Volume: 29 Pages: 3899-391

    • DOI

      10.1096/fj.15-271734

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08022, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-15H04838
  • [Journal Article] Nanosilica-induced placental inflammation and pregnancy complications: Different roles of the inflammasome components NLRP3 and ASC.2015

    • Author(s)
      Shirasuna K, Usui F, Karasawa T, Kimura H, Kawashima A, Mizukami H, Ohkuchi A, Nishimura S, Sagara J, Noda T, Ozawa K, Taniguchi S, Takahashi M
    • Journal Title

      Nanotoxicology.

      Volume: 11 Pages: 1-14

    • DOI

      10.3109/17435390.2014.956156

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25850222, KAKENHI-PROJECT-15K08022, KAKENHI-PROJECT-15K09146
  • [Journal Article] NLRP3 Deficiency Improves Angiotensin II-Induced Hypertension But Not Fetal Growth Restriction During Pregnancy.2015

    • Author(s)
      Shirasuna K, Karasawa T, Usui F, Kobayashi M, Komada T, Kimura A, Ohkuchi A, Taniguchi S, Takahashi M.
    • Journal Title

      Endocrinology

      Volume: 156 Pages: 4281-4292

    • DOI

      10.1210/en.2015-1408

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08022, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-24592482, KAKENHI-PROJECT-26461386
  • [Journal Article] Inflammasome Activation by Mitochondrial Oxidative Stress in Macrophages Leads to the Development of Angiotensin II-Induced Aortic Aneurysm2015

    • Author(s)
      Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, Yoshimura K, Aoki H, Tsutsui H, Noda T, Sagara J, Taniguchi S, Takahashi M
    • Journal Title

      Arteriosclerosis, Thrombosis, and Vascular Biology

      Volume: 35 Pages: 127-136

    • DOI

      10.1161/atvbaha.114.303763

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23591359, KAKENHI-PROJECT-24790775, KAKENHI-PROJECT-26461386, KAKENHI-PROJECT-15K08022, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-26670621
  • [Journal Article] 固形がんの嫌気的微小環境を標的とした持続的抗腫瘍性物質産生系の開発2015

    • Author(s)
      谷口 俊一郎
    • Journal Title

      展望

      Volume: 9 Pages: 37-42

    • Data Source
      KAKENHI-PROJECT-15K08022
  • [Journal Article] NFkB2 gene as a candidate that epigenetically responds to interval walking training2015

    • Author(s)
      Zhang Y, Hashimoto S, Fujii C, Hida S, Ito K, Matsumura T, Sakaizawa T, Morikawa M, Masuki S, Nose H, Higuchi K, Nakajima K, Taniguchi S
    • Journal Title

      Int. J Sports Med.

      Volume: in press Pages: 769-775

    • DOI

      10.1055/s-0035-1547221

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24240089, KAKENHI-PROJECT-24591419, KAKENHI-PROJECT-25350884, KAKENHI-PROJECT-25670117, KAKENHI-PROJECT-26460272, KAKENHI-PROJECT-15K08022, KAKENHI-PROJECT-15H01830
  • [Journal Article] NLRP3 regulates neutrophil functions and contributes to hepatic ischemia-reperfusion injury independently of inflammasomes.2014

    • Author(s)
      Inoue Y, Shirasuna K, Kimura H, Usui F, Kawashima A, Karasawa T, Tago K, Dezaki, Nishimura S, Sagara J, Noda T, IwakuraY, Hiroko Tsutsui H, Taniguchi S, Yanagisawa K, Yada T, Yasuda Y, Takahashi M.
    • Journal Title

      J Immunol.

      Volume: 192(9) Pages: 4342-4351

    • DOI

      10.4049/jimmunol.1302039

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23590566, KAKENHI-PROJECT-23591359, KAKENHI-PROJECT-25850222, KAKENHI-PROJECT-26440062, KAKENHI-PROJECT-26461386
  • [Journal Article] ASC in renal collecting duct epithelial cells contributes to inflammation and injury after unilateral ureteral obstruction.2014

    • Author(s)
      Komada T, Usui F, Shirasuna K, Kawashima A, Kimura H, Karasawa T, Nishimura S, Sagara J, Noda T, Taniguchi S, Muto S, Nagata D, Kusano E, Takahashi M
    • Journal Title

      Am J Pathol

      Volume: 184(5) Pages: 1287-1298

    • DOI

      10.1016/j.ajpath.2014.01.014

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23590566, KAKENHI-PROJECT-23591359, KAKENHI-PROJECT-25850222
  • [Journal Article] Nucleic acids sensing by T cells initiates Th2 cell differentiation2014

    • Author(s)
      Imanishi T, Ishihara C, Badr Mel S, Hashimoto-Tane A, Kimura Y, Kawai T, Takeuchi O, Ishii KJ, Taniguchi S, Noda T, Hirano H, Brombacher F, Barber GN, Akira S, Saito T
    • Journal Title

      Nat Commun.

      Volume: 10 Pages: 3566-3566

    • DOI

      10.1038/ncomms4566

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23590566, KAKENHI-PROJECT-24229004, KAKENHI-PROJECT-24790489, KAKENHI-PROJECT-26293107, KAKENHI-PROJECT-26670236
  • [Journal Article] ASC-associated inflammation promotes cecal tumorigenesis in aryl hydrocarbon receptor- deficient mice2013

    • Author(s)
      Togo Ikuta
    • Journal Title

      Carcinogenesis

      Volume: 印刷中 Pages: 1620-1627

    • DOI

      10.1093/carcin/bgt083

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22501001, KAKENHI-PROJECT-23590162, KAKENHI-PROJECT-23590566, KAKENHI-PUBLICLY-23114509
  • [Journal Article] Clinical significance of apotosis-associated speck-like protein containing a caspase recruitment domain in oral squamous cell carcinoma2013

    • Author(s)
      Shimane T, Kobayashi H, Takeoka M, Kitazawa M, Matsumura T, Hida S, Tiepeng Xiao, Koike T, Taniguchi S, Kurita H.
    • Journal Title

      Oral & Maxillofacial Pathology

      Volume: 115(6) Pages: 799-809

    • DOI

      10.1016/j.oooo.2013.03.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Journal Article] Beneficial innate signaling interference for antibacterial responses by a Toll-like receptor-mediated enhancement of the MKP-IRF3 axis2013

    • Author(s)
      Negishi H, Matsuki K, Endo N, Sarashina H. Miki S, Matsuda A, Fukazawa K, Taguchi-Atarashi N, Ikushima H, Yanai H, Nishio J, Honda K, Fujioka Y, Ohba Y, Noda T, Taniguchi S, Nishida E, Zhang Y, Chi H, Flavell RA, Taniguchi T
    • Journal Title

      Proc. Natl. Acad. Sci. U.S.A

      Volume: 49 Pages: 19884-19889

    • DOI

      10.1073/pnas.1320145110

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J04616, KAKENHI-PROJECT-11J05380, KAKENHI-PROJECT-12J04258, KAKENHI-PROJECT-13J06115, KAKENHI-PROJECT-13J10423, KAKENHI-PROJECT-23390090, KAKENHI-PROJECT-23590563, KAKENHI-PROJECT-23590566, KAKENHI-PROJECT-24590574, KAKENHI-PROJECT-25670184
  • [Journal Article] Crucial ro ole of hyaluronan in neointim mal formation after vascular in njury2013

    • Author(s)
      Kashima Y, Takahashi M, Shiba Y, Itano N, Izawa A, Koyama J, Nakayama J, Taniguchi S, Kimata K, Ikeda U.
    • Journal Title

      PLOS ONE

      Volume: 8

    • DOI

      10.1371/journal.pone.0058760

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570148, KAKENHI-PROJECT-23590566, KAKENHI-PROJECT-23591035, KAKENHI-PROJECT-23790843, KAKENHI-PROJECT-24591042, KAKENHI-PROJECT-24790750
  • [Journal Article] Critical role of caspase-1 in vascular inflammation and development of atherosclerosis in Western2012

    • Author(s)
      Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, Hida S, Sagara J, Taniguchi S, Takahashi M.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 425 Pages: 162-168

    • DOI

      10.1016/j.bbrc.2012.07.058

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590566, KAKENHI-PROJECT-23591359, KAKENHI-PROJECT-24591419, KAKENHI-PROJECT-24790775, KAKENHI-PROJECT-24890217, KAKENHI-PUBLICLY-24117709
  • [Journal Article] ASC plays a role in the priming phase of the immune response to type II collagen in collagen-induced arthritis2011

    • Author(s)
      Yamazaki Y, Takeoka M, Kitazawa M, Ehara T, Itano N, Kato H, Taniguchi S
    • Journal Title

      Rheumatol Int

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591939
  • [Journal Article] Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia reperfusion injury.2011

    • Author(s)
      Kawaguchi M, Takahashi M, Hata T, Kashima Y, Usui F, Morimoto H, Izawa A, Takahashi Y, Masumoto J, Koyama J, Hongo M, Noda T, Nakayama J, Sagara J, Taniguchi S, Ikeda U.
    • Journal Title

      Circulation

      Volume: 123 Pages: 594-604

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200077
  • [Journal Article] Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia reperfusion injury.2011

    • Author(s)
      Kawaguchi M, Takahashi M, Hata T, Kashima Y, Usui F, Morimoto, Izawa A, Takahashi Y, Masumoto J, Koyama J, Hongo M, Noda T, Nakayama J, Sagara J, Taniguchi S, Ikeda U.
    • Journal Title

      Circulation 123

      Pages: 594-604

    • Data Source
      KAKENHI-PROJECT-20200077
  • [Journal Article] ASC plays a role in the priming phase of the immune response to type II collagen in collagen-induced arthritis2011

    • Author(s)
      Hideshi Yamazaki. Michiko Takeoka. Masato Kitazawa. Takashi Ehara. Naoki Itano.Hiroyuki Kato. Shun' ichiro Taniguchi
    • Journal Title

      Rheumatology International Feb

      Volume: 18

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591939
  • [Journal Article] Exercise Effects on Methylation of ASC Gene.2010

    • Author(s)
      Nakajima K, Takeoka M, Mori M, Hashimoto S, Sakurai A, Nose H, Higuchi K, Itano N, Shiohara M, Oh T Taniguchi S.
    • Journal Title

      Int.J.Sports Med. 30

      Pages: 1-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012020
  • [Journal Article] Contribution of TIR domain-containing adapter inducing IFN-β mediated IL-18 Release to LPS-induced liver injury in mice.2009

    • Author(s)
      Imamura M, Tsutsui H, Yasuda K, Yumikura-Futatsugi S, Mitani K, Uchiyama R, Hayashi S, Akira S, Taniguchi S, Nico Van Rooijen, Jurg Tschopp, Yamamoto T, Fujimoto J, Nakanishi K.
    • Journal Title

      J.Hepatol. 51

      Pages: 333-341

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012020
  • [Journal Article] Splice Variant of ASC Regulates IL-β Release and Aggregates Differently from Intact ASC.2009

    • Author(s)
      Matsushita K, Takeoka M, Sagara J, Itano N, Kurose Y, Nakamura A, Taniguchi S.
    • Journal Title

      Mediators Inflamm. 2009

      Pages: 287387-287387

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012020
  • [Journal Article] Critical role of bone marrow apoptosis-associated speck-like protein, an inflammasome adaptor molecule, in neointimal formation after vascular injury in mice. 82008

    • Author(s)
      Yajima N, Takahashi M, Morimoto H, Shiba Y, Takahashi Y, Masumoto J, Ise H, Sagara J, Nakayama J, Taniguchi S, Ikeda U.
    • Journal Title

      Circulation. 17

      Pages: 3079-3087

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590385
  • [Journal Article] Conyribution of TIR domain-containing adapter inducing IFN-β mediated IL-18 release to LPS-induced liver injury in mice.2008

    • Author(s)
      Imamura M, Tsutsui H, Yasuda K, Yumikura -Futatsugi S, Mitani K, Uchiyama R, Hayashi S, Akira S, Taniguchi S, Nico Van Rooijen, Jurg Tschopp, Yamamoto T, Fujimoto J, Nakanishi K.
    • Journal Title

      J. Hepatology (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590385
  • [Journal Article] Critical role of bone marrow apoptosis-associated speck-like protein, an inflammasome adaptor molecule, in neointimal formation after vascular injury in mice. 82008

    • Author(s)
      Yajima N, Takahashi M, Morimoto H, Shiba Y, Takahashi Y, Masumoto J, Ise H, Sagara J, Nakavama J, Taniguchi S, Ikeda U.
    • Journal Title

      Circulation 17

      Pages: 3079-3087

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012020
  • [Journal Article] Critical role of bone marrow apoptosis-associated speck-like protein, an inflammasome adaptor molecule, in neointimal formation after vascular injury in mice2008

    • Author(s)
      Yajima N, Takahashi M, Morimoto H, Shiba Y, Takahashi Y, Masumoto J, Ise H, Sagara J, Nakayama J, Taniguchi S, Ikeda U
    • Journal Title

      Circulation 17

      Pages: 3079-3087

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590385
  • [Journal Article] Significance of Tumor-Associated Stroma in Promotion of Intratumoral Lymphangiogenesis: Pivotal Role of a Hyaluronan-Rich Tumor Microenviromment.2008

    • Author(s)
      Koyama H, Kobayashi N, Harada M, Takeoka M, Kawai Y, Sano K, Fujimori M, Amano, J., Ohhashi, T., Kannagi, R., Kimata, K., Taniguchi, S., Itano, N.
    • Journal Title

      Am. J. Pathol. 172

      Pages: 179-193

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590385
  • [Journal Article] Critical role of bone marrow apoptosis-associated speck-like protein, an inflammasome adaptor molecule, in neointimal formation after vascular injury in mice.2008

    • Author(s)
      Yajima N, Takahashi M, Morimoto H, Shiba Y, Takahashi Y, Masumoto J, Ise H, J Sagara, Nakayama J, Taniguchi S, Ikeda U.
    • Journal Title

      Circulation 117

      Pages: 3079-3087

    • Data Source
      KAKENHI-PROJECT-20200077
  • [Journal Article] Role of ASC in the Mouse Model of Helicobacter pylori Infection2008

    • Author(s)
      Benoit BN, Kobayashi M, Kawakubo M, Takeoka M, Sano K, Zou J, Itano N, Tsutsui H, Noda T, Fukuda M, Nakayama J, Taniguchi S
    • Journal Title

      J.Histochem & Cytochem 271

      Pages: 9-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590385
  • [Journal Article] Critical role of bone marrow-derived ASC, an inflammasome adaptor molecule, in neointimal formation after vascular injury in mice2008

    • Author(s)
      Yajima N, Takahashi M, Morimoto H, Shiba Y, Takahashi Y, Masumoto J, Ise H, J Sagara, Nakayama J, Taniguchi S, Ikeda U.
    • Journal Title

      Circulation 117

      Pages: 3079-3087

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200077
  • [Journal Article] Development of spontaneous optic neuropathy in NF-kBp50-deficient mice; Requirement for NF-kBp50 in ganglion cell survival.2007

    • Author(s)
      Takahashi Y, Katai N, Murata T, Taniguchi S, Hayashi T
    • Journal Title

      Neuropath, Applied Neurobiol. 33(6)

      Pages: 692-705

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590385
  • [Journal Article] Development of spontaneous optic neuropathy in NF-kBp50-deficient mice ; Requirement for NF-kBp50 in ganglion cell survival2007

    • Author(s)
      Takahashi Y, Katai N, Murata T, Taniguchi S, Hayashi T
    • Journal Title

      Neuropath, Applied Neurobiol 33(6)

      Pages: 692-705

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590385
  • [Journal Article] Regulatory molecules involved in inflammasome formation with special reference to a key mediator protein, ASC2007

    • Author(s)
      Taniguchi S, Sagara J
    • Journal Title

      Semin Immunopathol 29(3)

      Pages: 231-238

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590385
  • [Journal Article] Regulatory molecules involved in inflammasome formation with special reference to a key mediator protein, ASC.2007

    • Author(s)
      Taniguchi S, Sagara J.
    • Journal Title

      Semin Immunopathol. 29(3)

      Pages: 231-238

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590385
  • [Journal Article] Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.2006

    • Author(s)
      Yu JW, Taniguchi S, Sagara J, Alnemri ES. 他5名
    • Journal Title

      Cell death Differ. 13・2

      Pages: 236-249

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16570156
  • [Journal Article] Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.2006

    • Author(s)
      Yu JW, Taniguchi S, Sagara J, Alnemri ES. 他5名
    • Journal Title

      Cell Death Differ. 13・2

      Pages: 236-249

    • Data Source
      KAKENHI-PROJECT-16570156
  • [Journal Article] Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.2006

    • Author(s)
      Yu JW, Wu J, Zhang Z, Datta P, Ibrahimi I, Taniguchi S, Sagara J, Fernandes-Alnemri T, Alnemri ES
    • Journal Title

      Cell Death Differ. 13(2)

      Pages: 236-249

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16570156
  • [Journal Article] A proapototic protein ASC : a novel signal pathway for interleukin converting enzyme activation.2005

    • Author(s)
      Sagara J, Taniguchi S
    • Journal Title

      Chin.Immunol. 42(3)

      Pages: 306-312

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16570156
  • [Journal Article] Suppression of cancer phenotypes through a multifunctional actin-binding protein, calponin, that attacks cancer cells and simultaneously protects the host from invasion.2005

    • Author(s)
      Taniguchi S
    • Journal Title

      Cancer Sci. 96(11)

      Pages: 738-746

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16570156
  • [Journal Article] Dihydropyrimidine dehydrogenase expression predicts survival outcome and chemosensitivity to 5-fluorouracil in patients with oral squamous cell carcinoma.2005

    • Author(s)
      Kobayashi H, Sagara J, Taniguchi S. 他4名
    • Journal Title

      Oral Oncl. 41・1

      Pages: 38-47

    • Data Source
      KAKENHI-PROJECT-16570156
  • [Journal Article] Dihydropyrimidine dehydrogenase expression predicts survival outcome and chemosensitivity to 5-fluorouracil in patients with oral squamous cell carcinoma.2005

    • Author(s)
      Kobayashi H, Sagara J, Taniguchi S. 他4名
    • Journal Title

      Oral Oncol 41・1

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16570156
  • [Journal Article] Role of charged and hydrophobic residues in the oligomerization of PYRIN domain of ASC2005

    • Author(s)
      Moriya M, Taniguchi S, Wu P, Liepnish E, Otting G, Sagara J
    • Journal Title

      Biochemistry 44・2

      Pages: 575-583

    • Data Source
      KAKENHI-PROJECT-16570156
  • [Journal Article] Dihydropyrimidine dehydrogenase expression predicts survival outcome and chemosensitivity to 5-fluorouracil in patients with oral squamous cell carcinoma.2005

    • Author(s)
      Kobayashi H, Koike T, Nakatsuka A, Kurita H, Sagara J, Taniguchi S, Kurashina K
    • Journal Title

      Oral Oncol. 41(1)

      Pages: 38-47

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16570156
  • [Journal Article] Role of charged and hydrophobic residues in the oligomerization of the PYRIN domain of ASC.2005

    • Author(s)
      Moriya M, Taniguchi S, Wu P, Liepinsh E, Otting G, Sagara J
    • Journal Title

      Biochemistry 44(2)

      Pages: 575-583

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16570156
  • [Journal Article] Suppression of cancer phenotypes through a multifunctional actin-binding protein, calponin, that attacks cancer cells and simultaneously protects the host from invasion.2005

    • Author(s)
      Taniguchi S.
    • Journal Title

      Cancer Sci. 96・11

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16570156
  • [Journal Article] Suppression of cancer phenotypes through a multifunctional actin-binding protein, calponin, that attacks cancer cells and simultaneously protects the host from invasion.2005

    • Author(s)
      Taniguchi S
    • Journal Title

      Cancer Sci. 96.11

      Pages: 738-746

    • Data Source
      KAKENHI-PROJECT-16570156
  • [Journal Article] Role of charged and hydrophobic residues in the oligomerization of the PYRIN domain of ASC.2005

    • Author(s)
      Moriya M, Taniguchi S, Wu P, Liepinsh E, Otting G, Sagara J.
    • Journal Title

      Biochemistry. 44・2

      Pages: 575-583

    • Data Source
      KAKENHI-PROJECT-16021218
  • [Journal Article] Role of charged and hydrophobic residues in the oligomerization of the PYRIN domain of ASC.2005

    • Author(s)
      Moriya M, Taniguchi S, Sagara J. 他3名
    • Journal Title

      Biochemistry 44・2

      Pages: 575-583

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16570156
  • [Journal Article] ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules.2005

    • Author(s)
      Yamamoto M, Sagara J, Taniguchi S. 他9名
    • Journal Title

      Gene Cells 9・11

      Pages: 1055-1067

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16570156
  • [Journal Article] Suppression of cancer phenotypes through a multifunctional actin-binding protein, calponin, that attacks cancer cells and simultaneously protects the host from invasion.2005

    • Author(s)
      S.Taniguchi
    • Journal Title

      Cancer Science 96・11

      Pages: 738-746

    • Data Source
      KAKENHI-PROJECT-16659100
  • [Journal Article] ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules.2004

    • Author(s)
      Yamamoto M, Yaginuma K, Tsutsui H, Sagara J, Guan X, Seki E, Yasuda K, Yamamoto M, Akira S, Nakanishi K, Noda T, Taniguchi S
    • Journal Title

      Genes Cells 9(11)

      Pages: 1055-1067

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16570156
  • [Journal Article] 新規アポトーシス制御蛋白ASC:インターロイキン変換酵素の新しい活性化経路2004

    • Author(s)
      相良 淳二, 谷口 俊一郎
    • Journal Title

      臨床免疫 42・3

      Pages: 306-312

    • Data Source
      KAKENHI-PROJECT-16021218
  • [Journal Article] Clinical significance of cellular distribution of moesin in parients with oral squamous cell carcinoma.2004

    • Author(s)
      Kobayasi H, Sagara J, Kurita H, Morifuji M, Ohishi M, Kurashina K, Taniguchi S
    • Journal Title

      Clin. Cancer Res. 10(2)

      Pages: 572-580

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16570156
  • [Journal Article] Clinical significance of cellular distribution of moesin in parients with oral squamous cell carcinoma.2004

    • Author(s)
      Kobayashi H, Sagara J, Kurashina K, Taniguchi S. 他4名
    • Journal Title

      Clin. Cancer Res. 10・2

      Pages: 572-580

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16570156
  • [Journal Article] ASCとPYRINファミリー;新しいインターロイキン変換酵素活性化経路2004

    • Author(s)
      相良淳二, 谷口俊一郎
    • Journal Title

      信州医学雑誌 52・5

      Pages: 305-312

    • NAID

      130005416228

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16570156
  • [Journal Article] ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules.2004

    • Author(s)
      Yamamoto M, Yaginuma K, Tsutsui H, Sag ara J, Guan X, Seki E, Yasuda K, Yamamoto M, Akira S, Nakanishi K, Noda T, Taniguchi S.
    • Journal Title

      Genes Cells. 9・11

      Pages: 1056-1067

    • Data Source
      KAKENHI-PROJECT-16021218
  • [Journal Article] Impaired arterial pressure regulation during exercise due to enhanced muscular vasodilation in calponin knockout mice2003

    • Author(s)
      Masuki S, Takeoka M, Taniguchi S, Yokoyama M, Nose H.
    • Journal Title

      J Physiol 553

      Pages: 203-212

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570117
  • [Journal Article] Suppression of peritoneal dissemination through protecting mesothelial cells from retraction by cancer cells2003

    • Author(s)
      Hashimoto S, Takeoka M, Taniguchi S.
    • Journal Title

      Int.J.Cancer 107(4)

      Pages: 557-563

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570117
  • [Journal Article] Suppression of peritoneal dissemination through protecting mesothelial cells from retraction by cancer cells2003

    • Author(s)
      Hashimoto S, Takeoka M, Taniguchi S
    • Journal Title

      Int.J.Cancer 107

      Pages: 557-563

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570117
  • [Journal Article] Enhanced baroreflex sensitivity in free moving calponin knockout mice2003

    • Author(s)
      Masuki S, Takeoka M, Taniguchi S, Nose H.
    • Journal Title

      Am J Physiol Heart Circ Physiol. 284(3)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570117
  • [Journal Article] Reduced expression of actin-binding proteins, h-caldesmon and calponin hl, in the vascular smooth muscle inside melanoma lesions : an adverse prognostic factor for malignant melanoma2003

    • Author(s)
      Koganehira Y, Takeoka M, Ehara T, Sasaki K, Murata H, Saida T, Taniguchi S.
    • Journal Title

      Br J Dermatol 148(5)

      Pages: 971-980

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570117
  • [Journal Article] Methylation of ASC/TMS1, a proapoptotic gene responsible for activating procaspase-1, in human colorectal cancer2003

    • Author(s)
      Yokoyama T, Sagara J, Guan X, Masumoto J, Takeoka M, Komiyama Y, Miyata K, Higuchi K, Taniguchi S.
    • Journal Title

      Cancer Let 202

      Pages: 101-103

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570117
  • [Journal Article] Calponin h1 induced a flattened morphology and suppressed the growth of human fibrosarcoma HT1080 cells.2002

    • Author(s)
      Takeoka M, Ehara T, Sagara J, Hashimoto S, Taniguchi S.
    • Journal Title

      Eur J Cancer 38(3)

      Pages: 436-442

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570117
  • [Journal Article] Calponin h1 suppresses tumor growth of Src-induced transformed 3Y1 cells in association with a decrease in angiogenesis2002

    • Author(s)
      Kaneko M, Takeoka M, Oguchi M, Koganehira Y, Murata H, Ehara T, Tozuka M, Saida T, Taniguchi S
    • Journal Title

      Jpn J Cancer Res 93

      Pages: 935-943

    • NAID

      50000646613

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570117
  • [Journal Article] Nico Van Rooijen, Jurg Tschopp, Yamamoto T, Fujimoto J, Nakanishi K

    • Author(s)
      Imamura M, Tsutsui H, Yasuda K, Yumikura-Futatsugi S, Mitani K, Uchiyama R, Hayashi S, Akira S, Taniguchi S
    • Journal Title

      Conyribution of TIR domain-containingadapter inducing IFN-β mediated IL-18 release to LPS-induced liver injury in mice (In press)

    • Data Source
      KAKENHI-PROJECT-19590385
  • [Patent] 抗体遺伝子の発現・分泌システム2015

    • Inventor(s)
      谷口 俊一郎他
    • Industrial Property Rights Holder
      信州大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-04-17
    • Overseas
    • Data Source
      KAKENHI-PROJECT-15K08022
  • [Presentation] Immune modulation by Bifidobacteria-derived molecules2019

    • Author(s)
      Naoto Fujioka, Yuma Itoh, Shungo Sasaki, Saotomo Itoh, Shun’ichiro Taniguchi, Shigeaki Hida
    • Organizer
      日本免疫学学会
    • Data Source
      KAKENHI-PROJECT-18K06781
  • [Presentation] Enhanced Anti-tumor Effects of IFN- γ Producing Bifidobacterium in Combination with PD-1 Antibody in a Syngeneic Murine Model2019

    • Author(s)
      Satoshi KOBAYASHI , Yuji SEKI , Koichiro SHIOYA , Shiro KATAOKA , Li WANG , 1231 Yuko SHIMATANI , Minoru FUJIMORI , Shun’ichiro TANIGUCHI , Takaaki NAKAMURA
    • Organizer
      5th International Symposium for Medicinal Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06781
  • [Presentation] Enhanced anti-tumor effects of IFN-γ producing Bifidobacterium in combination with PD-1 antibody in a syngeneic murine model2019

    • Author(s)
      Satoshi Kobayashi, Yuji Seki, Koichiro Shioya, Shiro Kataoka, Li Wang, Yuko Shimatani, Minoru Fujimori, Shun'ichiro Taniguchi, Takaaki Nakamura1
    • Organizer
      5th International Symposium for Medicinal Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06781
  • [Presentation] Engineered bacterial cancer therapy using Bifidobacterium secreting agonistic anti-4-1BB scFv in the mouse model2019

    • Author(s)
      Tomio Matsumura, Koichiro Shioya, Yasuyoshi Kanari, Yuko Shimatani, Shiro Kataoka, Shun’ichiro Taniguchi, Takaaki Nakamura
    • Organizer
      5th International Symposium for Medicinal Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06781
  • [Presentation] Engineered Bacterial Cancer Therapy Using Bifidobacterium Secreting Agonistic Anti-4-1BB scFv in the Mouse Model2019

    • Author(s)
      Tomio MATSUMURA , Koichiro SHIOYA , Yasuyoshi KANARI , Yuko SHIMATANI , 1211 Shiro KATAOKA , Shun’ichiro TANIGUCHI , Takaaki NAKAMURA
    • Organizer
      5th International Symposium for Medicinal Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06781
  • [Presentation] Bifidobacterium producing interferon-γ induced tumor shrinkage in combination with anti-PD-1 blockade in syngeneic mouse model2018

    • Author(s)
      Shiro Kataoka, Satoshi Kobayashi , Yuji Seki, Koichiro Shioya, Li Wang, Yuko Shimatani, Takaaki Nakamura, Shun'ichiro Taniguchi
    • Organizer
      Keystone Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06781
  • [Presentation] Enhanced antitumor effects by a combination approach of interferon-g producing recombinant Bifidobacterium and anti-mPD-1 antibody in CT26 syngeneic mouse model2017

    • Author(s)
      S Kobayashi,Y. Seki K Shioya, S Ktaoka, L, Wang, Y Shimatani, M Fujimori, S Taniguchi
    • Organizer
      AACR
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08022
  • [Presentation] Novel role of ASC as a regulator of metastatic phenotype2016

    • Author(s)
      岡田なぎさ、藤井千文、松村富穂、北沢将人、谷口俊一郎、肥田重明、宇原久、奥山隆平
    • Organizer
      第41回研究皮膚科学会年次学術大会
    • Place of Presentation
      仙台国際センター(仙台市)
    • Year and Date
      2016-12-09
    • Data Source
      KAKENHI-PROJECT-26460272
  • [Presentation] インフラマソーム構成因子ASCの細胞運動における役割2016

    • Author(s)
      藤井千文、松村富穂、肥田重明、岡田なぎさ、谷口俊一郎
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26460272
  • [Presentation] インフラマソーム構成分子ASCの細胞運動における役割2016

    • Author(s)
      藤井千文、松村富穂、肥田重明、岡田なぎさ、谷口俊一郎
    • Organizer
      第75回日本癌学会学術集会
    • Place of Presentation
      横浜市
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K08022
  • [Presentation] がん細胞におけるアクチン束化タンパクfascin1による免疫制御機構2015

    • Author(s)
      松村富穂、谷口俊一郎、肥田重明
    • Organizer
      第74回日本癌学会学術集会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15K08022
  • [Presentation] ヒト肺癌の悪性形質獲得におけるASCの役割2015

    • Author(s)
      境澤隆夫、松村富穂、藤井千文、肥田重明、谷口俊一郎
    • Organizer
      第24回日本がん転移学会学術集会・総会
    • Place of Presentation
      大阪府大阪市シティプラザ大阪
    • Year and Date
      2015-07-23
    • Data Source
      KAKENHI-PROJECT-26460272
  • [Presentation] アクチン細胞骨格制御タンパクFascin1によるインターフェロン産生調節   機構の解析2015

    • Author(s)
      松村富穂、谷口俊一郎
    • Organizer
      第19回日本がん分子標的治療学会学術集会
    • Place of Presentation
      松山全日空ホテル(愛媛県松山市)
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PROJECT-15K08022
  • [Presentation] ヒト肺癌の悪性形質獲得におけるASCの役割2015

    • Author(s)
      境澤隆夫、松村富穂、藤井千文、肥田重明、谷口俊一郎
    • Organizer
      第24回日本がん転移学会学術集会・総会
    • Place of Presentation
      シティプラザ大阪(大阪市)
    • Year and Date
      2015-07-23
    • Data Source
      KAKENHI-PROJECT-15K08022
  • [Presentation] 固形がんへの抗 Immune Checkpoint 阻害分子デリバリーと持続的産生2015

    • Author(s)
      塩谷公一郎、谷口俊一郎 他
    • Organizer
      第74回日本癌学会学術集会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15K08022
  • [Presentation] がん細胞でのASCの発現量低下は細胞運動能を亢進させる2013

    • Author(s)
      藤井千文、松村富穂、伊藤賢祐、肥田重明、谷口俊一郎
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] Actin binding protein fascin1 regulates innate immune responses in tumor cells2013

    • Author(s)
      Matsumura T, Fujii C, Hida S, Taniguchi S
    • Organizer
      第42回日本免疫学会学術集会
    • Place of Presentation
      千葉市
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] Cell interaction triggers ASC-dependent pathway to mediate growth arrest and cell death.2013

    • Author(s)
      伊藤賢祐、北沢将人、藤井千文、肥田重明、谷口俊一郎
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] Silencing of ASC expression in tumor cells promotes cell migration and cell motillty.2013

    • Author(s)
      藤井千文、松村富穂、伊藤賢祐、肥田重明、谷口俊一郎
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] Actin binding protein fascin1 regulates innate immune responses in tumor cells.2013

    • Author(s)
      Matsumura T, Fujii C, Hida S, Taniguchi S
    • Organizer
      第42回日本免疫学会学術集会
    • Place of Presentation
      千葉市
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] 細胞間相互作用を介したASC依存的な腫瘍抑制機能2013

    • Author(s)
      伊藤賢祐、北沢将人、藤井千文、肥田重明、谷口俊一郎
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] 口腔扁平上皮癌におけるASC(PYD-CARD)の発現とアポトーシスの関連2012

    • Author(s)
      嶋根哲、相澤仁志、竹岡みち子、松村富穂、肥田重明、小池剛史、肖鉄朋、小林啓一、谷口俊一郎、栗田浩
    • Organizer
      第50回日本がん治療学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] Potential involvement of ASC in cancer progression and metastasis.2012

    • Author(s)
      Chifumi Fujii, Shigeaki Hida, Kensuke Ito, Masato Kitazawa, Shun'ichiro Taniguchi
    • Organizer
      Metastasis
    • Place of Presentation
      Brisbane
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] A novel tumor-suppressor functions of ASC in malignant cells2012

    • Author(s)
      伊藤賢祐、北沢将人、藤井千文、肥田重明、谷口俊一郎
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] Correlation between ASC (PYD-CARD) expression and cell differentiation in normal oral epithelium2012

    • Author(s)
      Tetsu Shimane, Michiko Takeoka, Hiroichi Kobayashi, Hitoshi Aizawa, Tiepeng Xiao, Tomio Matsumura, Takeshi Koike, Shigeaki Hida, Shunichiro Taniguchi, Hiroshi Kurita
    • Organizer
      ACOMS
    • Place of Presentation
      Bali-Indonesia
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] Correlation between ASC (PYD-CARD) expression and cell differentiation in normal oral epithelium2012

    • Author(s)
      Shimane T, Takeoka M, Kobayashi H, Aizawa H, Tiepeng Xiao, Matsumura T,Koike T, Hida S, Taniguchi S, Kurita H
    • Organizer
      ACOMS 2012
    • Place of Presentation
      Bali-Indonesia
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] A novel tumor-suppressor functions of ASC in malignant cells.2012

    • Author(s)
      伊藤賢祐、北沢将人、藤井千文、肥田重明、谷口俊一郎
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] 口腔扁平上皮癌におけるASC(PYD-CARD)の発現とアポトーシスの関連2012

    • Author(s)
      嶋根哲、相澤仁志、竹岡みち子、松村富穂、肥田重明、小池剛史、肖鉄朋、 小林啓一、谷口俊一郎、栗田浩
    • Organizer
      第50回日本がん治療学会学術集会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] ヒト線維肉腫細胞HT1080におけるASCによる増殖抑制メカニズムの解析2012

    • Author(s)
      北沢将人、谷口俊一郎
    • Organizer
      第16回日本がん分子標的治療学会学術集会
    • Place of Presentation
      北九州市
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] がん細胞におけるASCと細胞運動能の相関性の解析2012

    • Author(s)
      藤井千文、松村富穂、伊藤賢祐、北沢将人、肥田重明、谷口俊一郎
    • Organizer
      第85回日本生化学会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] Potential involvement of ASC in cancer progression and metastasis2012

    • Author(s)
      Fujii C, Hida S, Ito K, Kitazawa M, Taniguchi S
    • Organizer
      Metastasis
    • Place of Presentation
      Brisbane
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] マクロファージの抗腫瘍作用におけるASCの役割2011

    • Author(s)
      岡田なぎさ、北沢将人、藤井千文、肥田重明、谷口俊一郎
    • Organizer
      第20回日本がん転移学会学術集会・総会
    • Place of Presentation
      浜松
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] A novel tumor-suppressor function of ASC in fibrosarcoma2011

    • Author(s)
      北沢将人、肥田重明、岡田なぎさ、松村富穂、藤井千文、竹岡みち子、宮川眞一、谷口俊一郎
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] The role of apoptosis-associated speck-like protein containing a CARD (ASC) in Antitumor effect of macrophage.2011

    • Author(s)
      岡田なぎさ、北沢将人、藤井千文、肥田重明、谷口俊一郎
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] he role of apoptosis-associated speck-like protein containing a CARD (ASC) in Antitumor effect of macrophage2011

    • Author(s)
      岡田なぎさ、北沢将人、藤井千文、肥田重明、谷口俊一郎
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] novel tumor-suppressor function of ASC in fibrosarcoma2011

    • Author(s)
      北沢将人、肥田重明、岡田なぎさ、松村富穂、藤井千文、竹岡みち子、宮川眞一、谷口俊一郎
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] ASCによるヒト線維肉腫細胞HT1080の増殖抑制2011

    • Author(s)
      北沢将人、谷口俊一郎
    • Organizer
      第15回日本がん分子標的治療学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590566
  • [Presentation] ASC plays a role in the priming phase of the immune response to type II collagen in collagen-induced arthritis2010

    • Author(s)
      Yamazaki Y, Takeoka M, Kitazawa M, Ehara T, Itano N, Kato H, Taniguchi S
    • Organizer
      2010ACR annual scientific meeting
    • Place of Presentation
      Atlanta
    • Year and Date
      2010-11-10
    • Data Source
      KAKENHI-PROJECT-21591939
  • [Presentation] Role of inflammasome in cardiovascular diseases.2010

    • Author(s)
      Takahashi M, Taniguchi S.
    • Organizer
      14^<th> International Congress of Immunology
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20200077
  • [Presentation] ASC plays a role in the priming phase of the immune response to type II collagen in collagen-induced arthritis2010

    • Author(s)
      Yamazaki Y, Takeoka M, Kitazawa M, Ehara T, Itano N, Kato H, Taniguchi S
    • Organizer
      2010 ACR annual scientific meeting
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-21591939
  • [Presentation] Microenvironment-dependent function of ASC, a mediator protein for inflammasome and cell death, in carcinogenesis.2010

    • Author(s)
      Taniguchi S, Kitazawa M, Okada N, Asano H, Itano N, Takeoka M.
    • Organizer
      8^<th> Joint Conference of the American Association for Cancer Research and the Japanese Cancer Association
    • Place of Presentation
      Hawai, USA
    • Year and Date
      2010-02-07
    • Data Source
      KAKENHI-PROJECT-20012020
  • [Presentation] ASC Deleted Mice Are Resistant to Collagen-Induced Arthritis.2009

    • Author(s)
      Yamazaki H, Takeoka M, Ehara T, Itano N, Kato H, Taniguchi S.
    • Organizer
      ACR/ARHP Scientific Meeting
    • Place of Presentation
      Philadelphia, USA
    • Year and Date
      2009-10-20
    • Data Source
      KAKENHI-PROJECT-20012020
  • [Presentation] Deficiency of ASC (apotosis-associated speck-like protein containing a caspase recruitment domain) in bone marrow cells improved myocardial ischemia-reperfusion injury in mice.2009

    • Author(s)
      Kawaguchi M., Takahashi M, Hata T, Kashima Y, Takahashi Y, Sagara J, Taniguchi S, Ikeda U.
    • Organizer
      American Heart Association Scientific Sessions
    • Place of Presentation
      Orlando, USA
    • Data Source
      KAKENHI-PROJECT-20200077
  • [Presentation] Deficiency of ASC (apotosis-associatde speck-like protein containing a caspase recruitment domain) in bone marrow cells improved myocardial ischemia-reperfusion injury in mice.2009

    • Author(s)
      Kawaguchi,M., Takahashi.M., Hata,T., Kashima,Y., Takahashi,Y., Sagara,J., Taniguchi,S., Ikeda,U.
    • Organizer
      American Heart Association Scientific Sessions
    • Place of Presentation
      Orlando, U.S.A.
    • Data Source
      KAKENHI-PROJECT-20200077
  • [Presentation] Effects of high-intensity interval walking training from epigenetic point of view, focusing on methylation of ASC gene.2009

    • Author(s)
      谷口俊一郎
    • Organizer
      第4回国際シンポジウム/2009年度成果発表会
    • Place of Presentation
      軽井沢
    • Year and Date
      2009-08-03
    • Data Source
      KAKENHI-PROJECT-20012020
  • [Presentation] ASC Deleted Mice Are Resistant to Collagen-Induced Arthritis2009

    • Author(s)
      Yamazaki Y, Takeoka M, Kitazawa M, Ehara T, Itano N, Kato H, Taniguchi S
    • Organizer
      2009 ACR annual scientific meeting
    • Place of Presentation
      Philadelphia, USA
    • Data Source
      KAKENHI-PROJECT-21591939
  • [Presentation] 腫瘍免疫におけるApotosi9-associated speck-like protein containing a CARD (ASC)の役割2009

    • Author(s)
      岡田ぎさ、鄒健、竹岡みち子、板野直樹、谷口俊一郎
    • Organizer
      第18回日本がん転移学会学術集会・総会
    • Place of Presentation
      旭川
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-20012020
  • [Presentation] Cytosolic Pattern Recognition byMicrobes and Danger Signals Repeats Recognizing Pathogen-Associated Molecular Patterns, Have Been Gatnering Attention in the Field of Innate Tmmunity.2009

    • Author(s)
      Shun' ichiro Taniguchi
    • Organizer
      The 9^<th> World Congress on Inflammation
    • Place of Presentation
      Tokyo
    • Year and Date
      2009-07-08
    • Data Source
      KAKENHI-PROJECT-20012020
  • [Presentation] The role of apoptosis-associated speck-like protein containing a CARD(ASC) in tumor immunosurveillance.2009

    • Author(s)
      Okada N, Zou Jian, Kitazawa M, Kobayashi N, Takeoka M, Itano N, Taniguchi S.
    • Organizer
      68^<th> Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Year and Date
      2009-10-02
    • Data Source
      KAKENHI-PROJECT-20012020
  • [Presentation] Beta-catenin accmulation and ASC-mediated inflammation promote intestinal carcinogenesis in AhR-deficient mice.2009

    • Author(s)
      Ikuta T, Kobayashi Y, Kitazawa M, Itano N, Kurosumi M, Fujii Y, Taniguchi S, Kawajiri K.
    • Organizer
      68^<th> Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Year and Date
      2009-10-02
    • Data Source
      KAKENHI-PROJECT-20012020
  • [Presentation] Inflammasome activation in cardiac fibroblasts is essential for myocardial ischemia-reperfusion injury.2009

    • Author(s)
      Kawaguchi M, Takahashi M, Hata T, Kashima Y, Takahasni, Y, Sagara J, Taniguchi S, Ikeda U.
    • Organizer
      American Heart Association Scientific Sessions
    • Place of Presentation
      Orlando, USA
    • Data Source
      KAKENHI-PROJECT-20200077
  • [Presentation] Inflammasome activation in cardiac fibroblasts is essential for myocardial ischemia-reperfusion injury.2009

    • Author(s)
      Kawaguchi,M., Takahashi,M., Hata,T., Kashima,Y., Takahasni,Y., Sagara,J., Taniguchi,S., Ikeda,U.
    • Organizer
      American Heart Association Scientific Sessions
    • Place of Presentation
      Orlando, U.S.A.
    • Data Source
      KAKENHI-PROJECT-20200077
  • [Presentation] ASC-deleted mice are resistant to collagen-induced arthritis2009

    • Author(s)
      山崎秀、竹岡みち子、江原孝史、加藤博之、谷口俊一郎
    • Organizer
      2009 ACR annual scientific meeting
    • Place of Presentation
      Philadelphia
    • Year and Date
      2009-10-20
    • Data Source
      KAKENHI-PROJECT-21591939
  • [Presentation] Apoptosis-associated speck-like protein(ASC) promotes cell death through induction of cvclin D12008

    • Author(s)
      高橋康子、高橋将文、板野直樹、相良淳二、谷口俊一郎
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-20012020
  • [Presentation] Chronic High-Intensity Walking Exercise Alters DNA Methylation in Normal Middle-Aged and Older Subjects to Younger State2008

    • Author(s)
      Koki Nakajima, Michiko Takeoka, Masyuki Mori,Akihiro Sakurai,Hiroshi Nose, Keiichi Higuchi, Naoki Itano and Shun'ichiro Taniguchi
    • Organizer
      7th World Congress on Aging and Physical Activity
    • Place of Presentation
      Tsukuba
    • Data Source
      KAKENHI-PROJECT-19590385
  • [Presentation] Role of ASC protein in the mouse model of Helicobacter pyliro infection2008

    • Author(s)
      BEKALE NGUEMA BENOIT, Michiko Takeoka, Naoki Itano, JunNakayama, Shun'ichiro Taniguchi
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-20012020
  • [Presentation] 自然免疫と細胞死を制御する蛋白質ASCの腫瘍免疫における役割 : 欠損マウスを用いた解析2008

    • Author(s)
      鄒健、三好征司、小林宣隆、竹岡みち子、板野直樹、谷口俊一郎
    • Organizer
      第17回日本がん転移学会学術集会・総会
    • Place of Presentation
      鹿児島
    • Year and Date
      2008-07-25
    • Data Source
      KAKENHI-PROJECT-20012020
  • [Presentation] ASC regulates tumor immunity byIL-18/IFN-gamma axis2008

    • Author(s)
      鄒健、三好征司、小林宣隆、ベノイトベカレニュマ、竹岡みち子、板野直樹、谷口俊一郎
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-19590385
  • [Presentation] ASC regulates tumor immunity by IL-18/IFN-gamma axis2008

    • Author(s)
      鄒健、三好征司、小林宣隆、ベノイトベカレ ニュマ、竹岡みち子、板野直樹、谷口俊一郎
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-20012020
  • [Presentation] ASC regulates tumor immunity by IL-18/IFN-gamma axis.2008

    • Author(s)
      鄒健, 二好征司, 小林宣隆, ベノイトベカレ ニュマ, 竹岡みち子, 板野直樹, 谷口俊一郎
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-19590385
  • [Presentation] Chronic High-Intensity Walking Exercise Alters DNA Methylation in Normal Middle-Aged and Older Subjects to Younger State.2008

    • Author(s)
      Koki Nakajima, Michiko Takeoka, Masyuki Mori, Akihiro Sakurai, Hiroshi Nose, Keiichi Higuchi, Naoki Itano, Shun'ichiro Taniguchi
    • Organizer
      7th World Congress on Aging and Physical Activity
    • Place of Presentation
      Tsukuba
    • Year and Date
      2008-07-27
    • Data Source
      KAKENHI-PROJECT-19590385
  • [Presentation] ウォーキング運動のエピジェネティック効果-ASC遺伝子のメチル化に着目して-(第3報)2008

    • Author(s)
      中島弘毅, 竹岡みち子, 森政之, 櫻井晃洋, 能勢博, 樋口京一, 板野直樹, SUGRC, 谷口俊一郎
    • Organizer
      第31回日本基礎老化学会
    • Place of Presentation
      松本
    • Year and Date
      2008-06-12
    • Data Source
      KAKENHI-PROJECT-20012020
  • [Presentation] Chronic High-Intensity Walking Exercise Alters DNA Methylation in Normal Middle-Aged and Older Subjects to Younger State2008

    • Author(s)
      Koki Nakajima, Michiko Takeoka, Masyuki Mori, Akihiro Sakurai, Hiroshi Nose, Keiichi Higuchi, Naoki Itano and Shun'ichiro Taniguchi
    • Organizer
      7th World Congress on Aging and Physical Activity
    • Place of Presentation
      Tsukuba
    • Year and Date
      2008-07-27
    • Data Source
      KAKENHI-PROJECT-20012020
  • [Presentation] Apoptosis-associated speck-like protein(ASC) promotes cell death through induction of cyclin D12008

    • Author(s)
      高橋康子、相原淳二、板野直樹、谷口俊一郎
    • Organizer
      第31回日本分子生物学会年会第81回日本生化学学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-20012020
  • [Presentation] ウォーキング運動のエピジェネティック効果-ASC遺伝子のメチル化に着目して-(第3報)2008

    • Author(s)
      中島弘毅, 竹岡みち子, 森政之, 櫻井晃洋, 能勢博, 樋口京一, 板野直樹, SUGRC, 谷口俊一郎
    • Organizer
      第31回日本基礎老化学会
    • Place of Presentation
      松本
    • Data Source
      KAKENHI-PROJECT-19590385
  • [Presentation] ウォーキング運動のエピジェネティツク効果-ASC遺伝子のメチル化に着目して-(第3報)2008

    • Author(s)
      中島弘毅, 竹岡みち子, 森政之, 横井晃洋, 能勢博, 樋口京一, 板野直樹, SUGRC, 谷口俊一郎
    • Organizer
      第31回日本基礎老化学会
    • Place of Presentation
      松本
    • Year and Date
      2008-06-12
    • Data Source
      KAKENHI-PROJECT-19590385
  • [Presentation] Role of ASC protein in the mouse model of Helicobacter pyliro infection.2008

    • Author(s)
      BEKALE NGUEMA BENOIT, Michiko Takeoka, Naoki Itano, JunNakayama, Shun'ichiro Taniguchi
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-19590385
  • [Presentation] Role of an Inflammasome adaptor molecule ASC in myocardial ischemia-reperfusion injury.2008

    • Author(s)
      Kawaguchi M, Takahashi M, Hata T, Takahashi Y, Morimoto H, Ise H, Sagara J, Hongo M, Taniguchi S, Ikeda U.
    • Organizer
      American Heart Association Scientific Sessions
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-20200077
  • [Presentation] カスペース-1活性化シグナル経路のアダプター分子ASCスプライシング変異体(vASC)の機能解析2007

    • Author(s)
      松下一彦、相良淳二、谷口俊一郎
    • Organizer
      第37回日本免疫学会総会・学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19590385
  • [Presentation] ASC deficiency enhances autophagy for cell survival.2007

    • Author(s)
      Takahashi Y, Takahashi M, Itano N, Sagara J, Taniguchi S.
    • Organizer
      66th Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-19590385
  • [Presentation] 運動+乳製品摂取の生活習慣病予防効果:筋力と慢性炎症反応への影響

    • Author(s)
      増木静江、谷口俊一郎、能勢 博
    • Organizer
      第92回日本生理学会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2015-03-21 – 2015-03-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670117
  • [Presentation] アドレノメデュリン-RAMP2系は、血管恒常性を維持し、「癌転移前土壌」の形成を抑制する

    • Author(s)
      田中愛, 小山晃英, 桜井敬之, 神吉昭子, 河手久香, 新藤優佳, 植竹龍一, 山内啓弘, 五十嵐恭子, 鳥山佑一, 劉甜, 羨鮮, 今井章, 谷口俊一郎, 新藤隆行
    • Organizer
      第35回日本炎症・再生医学会
    • Place of Presentation
      沖縄、万国津梁館
    • Year and Date
      2014-07-01 – 2014-07-04
    • Data Source
      KAKENHI-PROJECT-26293183
  • [Presentation] アドレノメデュリン-RAMP2系は、血管恒常性を維持し、「癌転移前土壌」の形成を抑制する

    • Author(s)
      田中愛, 小山晃英, 桜井敬之, 神吉昭子, 河手久香, 新藤優佳, 植竹龍一, 山内啓弘, 五十嵐恭子, 鳥山佑一, 劉甜, 羨鮮, 今井章, 谷口俊一郎, 新藤隆行
    • Organizer
      第35回日本炎症・再生医学会
    • Place of Presentation
      沖縄、万国津梁館
    • Year and Date
      2014-07-01 – 2014-07-04
    • Data Source
      KAKENHI-PROJECT-26460337
  • [Presentation] 還元型コエンザイムQ10(CiQ10)摂取による高齢者の運動トレーニング実施率改善効果

    • Author(s)
      仲江真理、上條義一郎、小川 雄、片岡由布子、細江和典、谷口俊一郎、能勢 博
    • Organizer
      第69回日本体力医学会大会
    • Place of Presentation
      長崎大学文教キャンパス
    • Year and Date
      2014-09-19 – 2014-09-21
    • Data Source
      KAKENHI-PROJECT-25670117
  • [Presentation] 運動+乳製品の生活習慣病予防効果:筋力と慢性炎症反応への影響

    • Author(s)
      増木静江、谷口俊一郎、能勢 博
    • Organizer
      第92回日本生理学会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2015-03-21 – 2015-03-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-24240089
  • [Presentation] アドレノメデュリン-RAMP2システムは、血管恒常性を維持し、癌転移前土壌の形成を抑制する。

    • Author(s)
      田中愛, 桜井敬之, 神吉昭子, 河手久香, 新藤優佳, 小山晃英, 山内啓弘, 五十嵐恭子, 鳥山佑一, 劉甜, 羨鮮, 今井章, 谷口俊一郎, 新藤隆行
    • Organizer
      第32回内分泌代謝学サマーセミナー
    • Place of Presentation
      山梨、富士レークホテル
    • Year and Date
      2014-07-10 – 2014-07-12
    • Data Source
      KAKENHI-PROJECT-26460337
  • [Presentation] ASCによるがん細胞転移能の制御機構の解析

    • Author(s)
      藤井千文、松村富穂、肥田重明、谷口俊一郎
    • Organizer
      日本がん転移学会学術集会
    • Place of Presentation
      金沢市文化ホール・金沢ニューグランドホテル(石川県金沢市)
    • Year and Date
      2014-07-10 – 2014-07-11
    • Data Source
      KAKENHI-PROJECT-26460272
  • [Presentation] アドレノメデュリン-RAMP2システムは、血管恒常性を維持し、癌転移前土壌の形成を抑制する。

    • Author(s)
      田中愛、桜井敬之、神吉昭子、河手久香、新藤優佳、小山晃英、山内啓弘、五十嵐恭子、鳥山佑一、劉甜、 羨鮮、今井章、谷口俊一郎、新藤隆行
    • Organizer
      第32回内分泌代謝学サマーセミナー
    • Place of Presentation
      山梨、富士レークホテル
    • Year and Date
      2014-07-10 – 2014-07-12
    • Data Source
      KAKENHI-PROJECT-26293183
  • [Presentation] The roles of ASC in cancer cell metastasis

    • Author(s)
      Chifumi Fujii, Tomio Matsumura, Takao Sakaizawa, Shigeaki Hida, Shun'ichiro Taniguchi
    • Organizer
      15th International Biennial Congress Metastasis Research Society
    • Place of Presentation
      Heidelberg(ドイツ)
    • Year and Date
      2014-06-28 – 2014-07-01
    • Data Source
      KAKENHI-PROJECT-26460272
  • 1.  SAGARA Junji (10225831)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 26 results
  • 2.  竹市 雅俊 (00025454)
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  • 3.  NOSE Hiroshi (40128715)
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  • 4.  TAKEOKA Michiko (30197280)
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  • 5.  馬場 恒男 (70037323)
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  • 6.  貞野 宏之 (70187160)
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  • 7.  TSUKITA Shoichiro (50155347)
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  • 8.  HIDA Shigeaki (10345762)
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  • 11.  KOBAYASHI Hiroaki (70260700)
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  • 12.  関口 清俊 (50187845)
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  • 13.  江口 吾朗 (80022581)
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  • 137.  柴 祐司
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