• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Sugimoto Yoshikazu  杉本 芳一

ORCIDConnect your ORCID iD *help
… Alternative Names

SUGIMOTO Yoshikazu  杉本 芳一

杉本 芳一  スギモト ヨシカズ

Less
Researcher Number 10179161
Other IDs
External Links
Affiliation (Current) 2022: 慶應義塾大学, 薬学部(芝共立), 教授
Affiliation (based on the past Project Information) *help 2018 – 2021: 慶應義塾大学, 薬学部(芝共立), 教授
2016: 慶應義塾大学, 薬学部(芝共立), 教授
2011 – 2015: 慶應義塾大学, 薬学部, 教授
2008 – 2009: Keio University, 薬学部, 教授
2004 – 2007: 共立薬科大学, 薬学部, 教授 … More
2001 – 2003: 財団法人癌研究会, 癌化学療法センター・分子生物治療研究部, 部長
2000: 財団法人 癌研究会, 癌化学療法センター・分子生物治療研究部, 部長
1998 – 1999: 癌研究会, 癌化学療法センター, 主任研究員
1994: 東京大学, 癌研究会・癌化学療法センター, 研究員
1991: (財)癌研究会癌化学療法センター, 研究員
1991: 癌研究会癌化学療法センター, 基礎研究部, 研究員
1990 – 1991: (財)癌研究会, 癌化学療法センター, 研究員
1990: 癌研究会, 癌化学療法センター, 研究員
1990: 癌研究所化学療法センター, 研究員
1989: 癌研究所, 癌化学療法センター, 研究員
1988: 癌研究会癌化学療法センター, 基礎研究部, 研究員
1988: 癌研究所, 癌科学療法センター, 研究員
1987: (財)癌研究会, 癌化学療法センター・基礎研究部, 研究員
1986: (財)癌研究会癌化学療法センター, .PD学術振興会特別 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Basic Section 50020:Tumor diagnostics and therapeutics-related / Clinical oncology / Tumor therapeutics
Keywords
Principal Investigator
ABCG2 / ABC transporter / BCRP / SNP / estrogen / ABCB1 / がん幹細胞 / 抗癌剤耐性 / レトロウイルス / flavonoid … More / gefitinib / irinotecan / ABCトランスポーター / MDR1 / P-glycoprotein / がん分子標的治療 / 薬剤耐性 / トランスポーター / シグナル伝達 / G-protein受容体 / Adriamycin / Paclitaxel / 癌化学療法 / ステロイドホルモン / MDRI / ABCB5 / P-糖タンパク質 / 抗がん剤耐性 / ABC輸送体 / 分子標的治療 / がん分子標的治療薬 / がん分子標的薬 / AKT … More
Except Principal Investigator
抗癌剤耐性 / 耐性タンパク / 耐性遺伝子 / 癌転移 / ビンクリスチン / アドリアマイシン / カルシウム拮抗薬 / 細胞接着分子 / 転移と糖蛋白質 / 癌遺伝子 / 抗癌剤 / モノクローナル抗体 / 多剤耐性遺伝子 / Pー糖蛋白 / 耐性克服 / DNAトポイソメラ-ゼ / モノクロ-ナル抗体 / 耐性獲得 / メタロチオネイン / グルタチオン・チオ-ル・トランスフェラ-ゼ / 5ーフルオロウラシル耐性 / Pー糖タンパク / 転移 / 細胞接着因子 / homing receptor / 運動因子 / src関連遺伝子 / アクチン / fos遺伝子 / 遺伝的不安定性 / 耐性獲得機序 / 耐性克服剤開発 / シスプラチン / 5ーフルオロウラシル / P‐糖タンパク / ユビキチン / トポイソメラ-ゼ / P-糖タンパク / 分子標的 / アポトーシス / 癌移転 / 遺伝子治療 / ベクター開発 / カルシウム培抗薬 / 転移と血小板凝集活性 Less
  • Research Projects

    (22 results)
  • Research Products

    (119 results)
  • Co-Researchers

    (51 People)
  •  複数のがん分子標的治療薬の効果を左右する薬剤耐性・感受性規定因子の統合的研究Principal Investigator

    • Principal Investigator
      杉本 芳一
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Keio University
  •  Analysis of the resistance mechanisms to molecular-targeting anticancer agentsPrincipal Investigator

    • Principal Investigator
      Sugimoto Yoshikazu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Keio University
  •  Identification of factors regulating the capacity for both self-renewal and pluripotent differentiation of cancer stem cells and application to cancer treatment.Principal Investigator

    • Principal Investigator
      Sugimoto Yoshikazu
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor therapeutics
    • Research Institution
      Keio University
  •  Molecular mechanism on the drug resistance and responsiveness against anticancer agents and molecular-target agentsPrincipal Investigator

    • Principal Investigator
      SUGIMOTO Yoshikazu
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Clinical oncology
    • Research Institution
      Keio University
  •  トランスポーターの発現・活性の制御と機能性SNPを基盤としたがん化学療法の戦略Principal Investigator

    • Principal Investigator
      杉本 芳一
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University
  •  薬物排出トランスポーターの活性制御と機能性SNPを基盤としたがん化学療法の戦略Principal Investigator

    • Principal Investigator
      杉本 芳一
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoritsu University of Pharmacy
  •  抗がん剤耐性の克服と機能性SNPを基盤としたがん化学療法の戦略Principal Investigator

    • Principal Investigator
      杉本 芳一
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoritsu University of Pharmacy
  •  レトロウイルス遺伝子導入を用いた抗癌剤耐性・感受性機構の研究Principal Investigator

    • Principal Investigator
      杉本 芳一
    • Project Period (FY)
      2001 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoritsu University of Pharmacy
      Japanese Foundation For Cancer Research
  •  癌および正常細胞の抗癌剤感受性を規定するサプレッサー型耐性因子の同定Principal Investigator

    • Principal Investigator
      杉本 芳一
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Japanese Foundation For Cancer Research
  •  がん遺伝子治療ベクターの基礎研究

    • Principal Investigator
      斎藤 泉
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  がん細胞の薬剤感受性と抵抗性の分子機構とその制御

    • Principal Investigator
      鶴尾 隆
    • Project Period (FY)
      1994 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  癌転移に関与する細胞側要因の解析

    • Principal Investigator
      丹羽 太貫
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hiroshima University
  •  新しい制がん剤耐性遺伝子群の解析と克服法の確立

    • Principal Investigator
      桑野 信彦
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      大分医科大学
  •  難治性癌の薬剤抵抗性の分子機構とその克服

    • Principal Investigator
      鶴尾 隆
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  癌転移に関与する細胞側要因の解析

    • Principal Investigator
      横路 謙次郎
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hiroshima University
  •  新しい制がん剤耐性遺伝子群の解析と克服法の確立

    • Principal Investigator
      桑野 信彦
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      大分医科大学
  •  難治性癌の薬剤抵抗性の分子機構とその克服

    • Principal Investigator
      鶴尾 隆
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  癌転移に関与する細胞側要因の解析

    • Principal Investigator
      横路 謙次郎
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hiroshima University
  •  癌転移に関する基礎的研究

    • Principal Investigator
      横路 謙次郎
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hiroshima University
  •  制がん剤耐性機構とその克服

    • Principal Investigator
      鶴尾 隆
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  制がん剤耐性機構とその克服

    • Principal Investigator
      鶴尾 隆
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  制がん剤耐性機構とその克服

    • Principal Investigator
      鶴尾 隆
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2009 2007 2005

All Journal Article Presentation

  • [Journal Article] Effect of TNIK upregulation on JQ1-resistant human colorectal cancer HCT116 cells.2020

    • Author(s)
      Takahashi Chihiro、Kondo Shingo、Sadaoka Kensuke、Ishizuka Shuhei、Noguchi Kohji、Kato Yu、Sugimoto Yoshikazu
    • Journal Title

      Biochemical and Biophyssical Research Communications.

      Volume: 530 Pages: 230-234

    • DOI

      10.1016/j.bbrc.2020.06.136

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K16339, KAKENHI-PROJECT-18K06632, KAKENHI-PROJECT-18K07302
  • [Journal Article] STAT1 upregulates glutaminase and modulates amino acids and glutathione metabolism2020

    • Author(s)
      Kondo S, Kato Y, Minagawa S, Sugimoto Y.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 523 Pages: 672-677

    • DOI

      10.1016/j.bbrc.2020.01.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07302, KAKENHI-PROJECT-20K16339
  • [Journal Article] Putative molecular determinants mediating sensitivity or resistance towards carnosic acid tumor cell responses2020

    • Author(s)
      Mahmoud Nuha、Saeed Mohamed E.M.、Sugimoto Yoshikazu、Klinger Anette、Fleischer Edmond、Efferth Thomas
    • Journal Title

      Phytomedicine

      Volume: 77 Pages: 153271-153271

    • DOI

      10.1016/j.phymed.2020.153271

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Journal Article] SERCA and P-glycoprotein inhibition and ATP depletion are necessary for celastrol-induced autophagic cell death and collateral sensitivity in multidrug-resistant tumor cells.2020

    • Author(s)
      Xu SW, Law BYK, Qu SLQ, Hamdoun S, Chen J, Zhang W, Guo JR, Wu AG, Mok SWF, Zhang DW, Xia C, Sugimoto Y, Efferth T, Liu L, Wong VKW.
    • Journal Title

      Pharmacological Research

      Volume: 153 Pages: 104660-104660

    • DOI

      10.1016/j.phrs.2020.104660

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Journal Article] GZD824 Inhibits GCN2 and Sensitizes Cancer Cells to Amino Acid Starvation Stress.2020

    • Author(s)
      Kato Yu、Kunimasa Kazuhiro、Takahashi Mizuki、Harada Ayaka、Nagasawa Ikuko、Osawa Masanori、Sugimoto Yoshikazu、Tomida Akihiro
    • Journal Title

      Mol Pharmacol.

      Volume: 98 Pages: 669-676

    • DOI

      10.1124/molpharm.120.000070

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K16339, KAKENHI-PUBLICLY-19H04973, KAKENHI-PROJECT-19H03526, KAKENHI-PROJECT-18K07302, KAKENHI-PROJECT-18K07309, KAKENHI-PROJECT-18K19486
  • [Journal Article] Citrus Fruit-Derived Flavanone Glycoside Narirutin is a Novel Potent Inhibitor of Organic Anion-Transporting Polypeptides2020

    • Author(s)
      Morita T, Akiyoshi T, Sato R, Uekusa Y, Katayama K, Yajima K, Imaoka A, Sugimoto Y, Kiuchi F, Ohtani H.
    • Journal Title

      Journal of Agricultural and Food Chemistry

      Volume: 68 Pages: 14182-14191

    • DOI

      10.1021/acs.jafc.0c06132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07173, KAKENHI-PROJECT-18K06758, KAKENHI-PROJECT-18K07302
  • [Journal Article] pH-Dependent transport kinetics of human organic anion transporting polypeptide 1A2.2020

    • Author(s)
      T. Morita, T Akiyoshi, R. Sato, K. Katayama, K. Yajima, H. Kataoka, A. Imaoka, Y. Sugimoto, H. Ohtani
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 35 Issue: 2 Pages: 220-227

    • DOI

      10.1016/j.dmpk.2019.12.002

    • NAID

      50014558590

    • ISSN
      1347-4367
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06758, KAKENHI-PROJECT-19K07173, KAKENHI-PROJECT-18K07302
  • [Journal Article] SNAIL- and SLUG-induced side population phenotype of HCT116 human colorectal cancer cells and its regulation by BET inhibitors.2020

    • Author(s)
      Kato Y, Kondo S, Itakura T, Tokunaga M, Hatayama S, Katayama K, Sugimoto Y.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 521 Pages: 152-157

    • DOI

      10.1016/j.bbrc.2019.10.094

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Journal Article] Cytotoxicity of cucurbitacin E from Citrullus colocynthis against multidrug-resistant cancer cells.2019

    • Author(s)
      Saeed MEM, Boulos JC, Elhaboub G, Rigano D, Saab A, Loizzo MR, Hassan LEA, Sugimoto Y, Piacente S, Tundis R, Yagi S, Khalid H, Efferth T.
    • Journal Title

      Phytomedicine

      Volume: 62 Pages: 152945-152945

    • DOI

      10.1016/j.phymed.2019.152945

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Journal Article] Regorafenib-Induced Hand-Foot Skin Reaction is More Severe on the Feet than on the Hands.2019

    • Author(s)
      Nonomiya Yuma、Yokokawa Takashi、Kawakami Kazuyoshi、Kobayashi Kazuo、Aoyama Takeshi、Takiguchi Tomomi、Sugisaki Takahito、Suzuki Kenichi、Suenaga Mitsukuni、Wakatsuki Takeru、Yamaguchi Kensei、Sugimoto Yoshikazu、Hama Toshihiro
    • Journal Title

      Oncology Research

      Volume: 印刷中

    • DOI

      10.3727/096504018x15291727589740

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07280, KAKENHI-PROJECT-18K07302
  • [Journal Article] Synthesis of 5-Hydroxy-3′,4′,7-trimethoxyflavone and Related Compounds and Elucidation of Their Reversal Effects on BCRP/ABCG2-Mediated Anticancer Drug Resistance2019

    • Author(s)
      Tsunekawa R, KatayamaK, Hanaya K, Higashibayashi S, Sugimoto Y, Sugai T.
    • Journal Title

      ChemBioChem

      Volume: 20 Pages: 210-220

    • DOI

      10.1002/cbic.201800431

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07302, KAKENHI-PROJECT-16K21362
  • [Journal Article] Novel pharmacological effects of poly (ADP-ribose) polymerase inhibitor rucaparib on the lactate dehydrogenase pathway2019

    • Author(s)
      Nonomiya Y, Noguchi K, Katayama K, Sugimoto Y.
    • Journal Title

      Biochemical and Biophysical Research Communicaions

      Volume: 510 Pages: 501-507

    • DOI

      10.1016/j.bbrc.2019.01.133

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07302, KAKENHI-PROJECT-18J11600, KAKENHI-PROJECT-18K06632
  • [Journal Article] Cytotoxicity of 40 Egyptian plant extracts targeting mechanisms of drug-resistant cancer cells.2019

    • Author(s)
      Hegazy MF, Abdelfatah S, Hamed AR, Mohamed TA, Elshamy AA, Saleh IA, Reda EH, Abdel-Azim NS, Shams KA, Sakr M, Sugimoto Y, Pare PW, Efferth T.
    • Journal Title

      Phytomedicine

      Volume: 59 Pages: 152771-152771

    • DOI

      10.1016/j.phymed.2018.11.031

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Journal Article] Collateral sensitivity of drug-resistant ABCB5- and mutation-activated EGFR overexpressing cells towards resveratrol due to modulation of SIRT1 expression.2019

    • Author(s)
      Saeed MEM, Rahama M, Kuete V, Dawood M, Elbadawi M, Sugimoto Y, Efferth T.
    • Journal Title

      Phytomedicine

      Volume: 59 Pages: 152890-152890

    • DOI

      10.1016/j.phymed.2019.152890

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Journal Article] Heat shock protein 90 inhibitors overcome the resistance to Fms-like tyrosine kinase 3 inhibitors in acute myeloid leukemia.2018

    • Author(s)
      Katayama K, Noguchi K, Sugimoto Y.
    • Journal Title

      Oncotarget

      Volume: 9 Pages: 34240-34258

    • DOI

      10.18632/oncotarget.26045

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06632, KAKENHI-PROJECT-18K07302
  • [Journal Article] Repurposing of Bromocriptine for Cancer Therapy.2018

    • Author(s)
      Seo EJ, Sugimoto Y, Greten HJ, Efferth T.
    • Journal Title

      Frontiers in Pharmacology

      Volume: 9 Pages: 1030-1030

    • DOI

      10.3389/fphar.2018.01030

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Journal Article] Betulinic Acid Exerts Cytotoxic Activity Against Multidrug-Resistant Tumor Cells via Targeting Autocrine Motility Factor Receptor (AMFR).2018

    • Author(s)
      Saeed MEM, Mahmoud N, Sugimoto Y, Efferth T, Abdel-Aziz H.
    • Journal Title

      Frontiers in Pharmacology

      Volume: 9 Pages: 481-481

    • DOI

      10.3389/fphar.2018.00481

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Journal Article] Protein kinase C alpha-mediated phosphorylation of PIM-1L promotes the survival and proliferation of acute myeloid leukemia cells.2018

    • Author(s)
      Takami M, Katayama K, Noguchi K, Sugimoto Y.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 503 Pages: 1364-1371

    • DOI

      10.1016/j.bbrc.2018.07.049

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06632, KAKENHI-PROJECT-18K07302
  • [Journal Article] Cell-based chemical fingerprinting identifies telomeres and lamin A as modifiers of DNA damage response in cancer cells2018

    • Author(s)
      Fujiwara C, Muramatsu Y, Nishii M, Tokunaka K, Tahara H, Ueno M, Yamori T, Sugimoto Y, Seimiya H.
    • Journal Title

      Scientific Reports

      Volume: 8 Pages: 14827-14827

    • DOI

      10.1038/s41598-018-33139-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07502, KAKENHI-PROJECT-18K07302, KAKENHI-PROJECT-18K19487, KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-16H04716, KAKENHI-PROJECT-16H06276
  • [Journal Article] BCR-ABL tyrosine kinase inhibition induces metabolic vulnerability by preventing the integrated stress response in K562 cells2018

    • Author(s)
      Kato Y, Kunimasa K, Sugimoto Y, Tomida A.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 504 Pages: 721-726

    • DOI

      10.1016/j.bbrc.2018.09.032

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07302, KAKENHI-PROJECT-18K07309, KAKENHI-PROJECT-16H04717
  • [Journal Article] Cytotoxicity of nimbolide towards multidrug-resistant tumor cells and hypersensitivity via cellular metabolic modulation.2018

    • Author(s)
      Mahmoud N, Saeed MEM, Sugimoto Y, Klauck SM, Greten HJ, Efferth T.
    • Journal Title

      Oncotarget

      Volume: 9 Pages: 35762-35779

    • DOI

      10.18632/oncotarget.26299

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Journal Article] Cytotoxicity of sesquiterpene alkaloids from Nuphar plants toward sensitive and drug-resistant cell lines.2018

    • Author(s)
      Fukaya M, Nakamura S, Hegazy MEF, Sugimoto Y, Hayashi N, Nakashima S, Yoshikawa M, Efferth T, Matsuda H.
    • Journal Title

      Food & Function

      Volume: 9 Pages: 6279-6286

    • DOI

      10.1039/c8fo01804a

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Journal Article] Functional Effects of AKT3 on Aurora Kinase Inhibitor-induced Aneuploidy.2017

    • Author(s)
      Noguchi K, Hongama K, Hariki S, Nonomiya Y, Katayama K, Sugimoto Y.
    • Journal Title

      J Biol Chem

      Volume: 292(5) Pages: 1910-1924

    • DOI

      10.1074/jbc.m116.747048

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460076, KAKENHI-PROJECT-15K14409
  • [Journal Article] APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer.2017

    • Author(s)
      Noritaka Tanaka, Tetsuo Mashima, Anna Mizutani, Ayana Sato, Aki Aoyama, Bo Gong, Haruka Yoshida, Yukiko Muramatsu, Kento Nakata, Masaaki Matsuura, Ryohei Katayama, Satoshi Nagayama, Naoya Fujita, Yoshikazu Sugimoto, Hiroyuki Seimiya
    • Journal Title

      Mol Cancer Ther.

      Volume: 16 Pages: 739-751

    • DOI

      10.1158/1535-7163.mct-16-0578

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H02368, KAKENHI-PROJECT-16H04715, KAKENHI-PROJECT-26430177, KAKENHI-PROJECT-15K14409, KAKENHI-PROJECT-15K14412, KAKENHI-PROJECT-16H04716
  • [Journal Article] RSK1 protects P-glycoprotein/ABCB1 against ubiquitin-proteasomal degradation by downregulating the ubiquitin-conjugating enzyme E2R1.2016

    • Author(s)
      Katayama K, Fujiwara C, Noguchi K, Sugimoto Y.
    • Journal Title

      Sci Rep

      Volume: 6 Pages: 36134-36134

    • DOI

      10.1038/srep36134

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460076, KAKENHI-PROJECT-15K14409
  • [Journal Article] Effect of AKT3 expression on MYC- and caspase-8-dependent apoptosis caused by polo-like kinase inhibitors in HCT 116 cells.2016

    • Author(s)
      Nonomiya Y, Noguchi K, Tanaka N, Kasagaki T, Katayama K, Sugimoto Y.
    • Journal Title

      Cancer Sci

      Volume: 107(12) Pages: 1877-1887

    • DOI

      10.1111/cas.13093

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460076, KAKENHI-PROJECT-15K14409
  • [Journal Article] Cytotoxicity of 35 medicinal plants from Sudan towards sensitive and multidrug-resistant cancer cells.2015

    • Author(s)
      Saeed ME, Abdelgadir H, Sugimoto Y, Khalid HE, Efferth T
    • Journal Title

      J Ethnopharmacol

      Volume: 174 Pages: 644-658

    • DOI

      10.1016/j.jep.2015.07.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Journal Article] Upregulation of cellular glutathione levels in human ABCB5- and murine Abcb5-transfected cells.2015

    • Author(s)
      Kondo S, Hongama K, Hanaya K, Yoshida R, Kawanobe T, Katayama K, Noguchi K, Sugimoto Y
    • Journal Title

      BMC Pharmacol Toxicol

      Volume: 16 Pages: 37-37

    • DOI

      10.1186/s40360-015-0038-5

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460076, KAKENHI-PROJECT-15K14409
  • [Journal Article] Activity of the dietary flavonoid, apigenin, against multidrug-resistant tumor cells as determined by pharmacogenomics and molecular docking.2015

    • Author(s)
      Mohamed Saeed, Yosikazu Sugimoto, et al.
    • Journal Title

      J Nutr Biochem

      Volume: VOL. 26 Pages: 44-56

    • DOI

      10.1016/j.jnutbio.2014.09.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300364, KAKENHI-PROJECT-15K14409
  • [Journal Article] Cytotoxicity of the sesquiterpene lactones neoambrosin and damsin from Ambrosia maritima against multidrug-resistant cancer cells.2015

    • Author(s)
      Saeed M, Jacob S, Sandjo, L, Sugimoto Y, Khalid H, Opatz T, Thines T, Efferth T
    • Journal Title

      Front Pharmacology

      Volume: 6 Pages: 267-267

    • DOI

      10.3389/fphar.2015.00267

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Journal Article] The lignan, (-)-sesamin reveals cytotoxicity toward cancer cells: pharmacogenomic determination of genes associated with sensitivity or resistance.2014

    • Author(s)
      Mohamed Saeed, Yosikazu Sugimoto, et al.
    • Journal Title

      Phytomedicine

      Volume: VOL. 21 Pages: 689-696

    • DOI

      10.1016/j.phymed.2014.01.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300364
  • [Journal Article] Regulations of P-Glycoprotein/ABCB1/MDR1 in Human Cancer Cells.2014

    • Author(s)
      Kazuhiro Katayama, Yoshikazu Sugimoto, et al.
    • Journal Title

      New Journal of Science

      Volume: VOL. 2014 Pages: 476974-476974

    • DOI

      10.1155/2014/476974

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23300364
  • [Journal Article] Human ABC transporter ABCG2/BCRP expression in chemoresistance: basic and clinical perspectives for molecular cancer therapeutics.2014

    • Author(s)
      Kohji Noguchi, Yoshikazu Sugimoto, et al.
    • Journal Title

      Pharmacogenomics and Personalized Medicine

      Volume: VOL. 7 Pages: 53-64

    • DOI

      10.2147/pgpm.s38295

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23300364
  • [Journal Article] FBXO15 regulates P-glycoprotein/ABCB1 expression through the ubiquitin-proteasome pathway in cancer cells2014

    • Author(s)
      Kazuhiro Katayama, Yoshikazu Sugimoto, et al.
    • Journal Title

      Cancer Science

      Volume: VOL. 345 Pages: 124-131

    • DOI

      10.1016/j.canlet.2013.12.007

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23300364, KAKENHI-PROJECT-23590134
  • [Journal Article] Resistance mechanisms of cancer cells to the novel vacuolar H+-ATPase inhibitor archazolid B.2014

    • Author(s)
      Rebecca Hamm, Yoshikazu Sugimoto, et al.
    • Journal Title

      Investigational New Drugs

      Volume: VOL. 32 Pages: 893-903

    • DOI

      10.1007/s10637-014-0134-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300364
  • [Journal Article] FBXO15 regulates P-glycoprotein/ABCB1 expression through the ubiquitin-proteasome pathway in cancer cells.2013

    • Author(s)
      Kazuhiro Katayama, Yoshikazu Sugimoto, et al.
    • Journal Title

      Cancer Sci

      Volume: 104 Pages: 694-702

    • DOI

      10.1111/cas.12145

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300364, KAKENHI-PROJECT-23590134, KAKENHI-PROJECT-23790196
  • [Journal Article] Biochemical Interaction of Anti-HCV Telaprevir with the ABC Transporters P-glycoprotein and Breast Cancer Resistance Protein.2013

    • Author(s)
      Yurua F, Yoshikazu Sugimoto, et al.
    • Journal Title

      BMC Research Notes

      Volume: 6 Pages: 445-445

    • DOI

      10.1186/1756-0500-6-445

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300364, KAKENHI-PROJECT-23590134
  • [Journal Article] Decidua-Derived Mesenchymal Cells are a Promising Source for the Generation and Cell Banking, of Human Induced Pluripotent Stem Cells2013

    • Author(s)
      Tomoko Shofuda, Yoshikazu Sugimoto, et al.
    • Journal Title

      Cell Med

      Volume: 4 Pages: 125-147

    • DOI

      10.3727/215517912x658918

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300364, KAKENHI-PROJECT-23689017, KAKENHI-PROJECT-24591538
  • [Journal Article] Breast Cancer Resistance Protein (BCRP) : a Molecular Target for Anticancer Drug Resistance and Pharmacokinetics/Pharmacodynamics.2005

    • Author(s)
      Sugimoto, Y.
    • Journal Title

      Cancer Sci. 96

      Pages: 457-465

    • Data Source
      KAKENHI-PROJECT-17016069
  • [Presentation] SLUG導入HCT116細胞に対するGPX4阻害剤の効果2021

    • Author(s)
      深澤ゆかり, 加藤優, 近藤慎吾, 杉本芳一.
    • Organizer
      日本薬学会第141年会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] Dextranによる多剤耐性関連輸送体の阻害効果2021

    • Author(s)
      森本かおり, 石井敬, 杉本芳一, 荻原琢男, 富田幹雄.
    • Organizer
      日本薬学会第141年会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] FLT3-ITDによるintegrated stress response の誘導2021

    • Author(s)
      佐々木大河, 加藤優, 片山和浩, 近藤慎吾, 杉本芳一.
    • Organizer
      日本薬学会第141年会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] SLUG導入HCT116細胞におけるxCTの発現上昇とフェロトーシス抵抗性2020

    • Author(s)
      加藤優, 近藤慎吾, 杉本芳一.
    • Organizer
      第24回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] GZD824のGCN2-ATF4ストレス応答経路に対する阻害効果2020

    • Author(s)
      高橋瑞希, 加藤優, 國政和弘, 杉本芳一, 冨田章弘.
    • Organizer
      第24回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] SLUG導入HCT116細胞におけるフェロトーシス感受性規定因子の解明2020

    • Author(s)
      加藤優, 近藤慎吾, 杉本芳一.
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] STAT1が関与する薬剤耐性とその克服2020

    • Author(s)
      近藤慎吾, 加藤優, 杉本芳一.
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] ウイルス転写因子K-RTAによるヒトCD274/PD-L1プロモーター活性化.2019

    • Author(s)
      野口耕司, 宮澤雅典, 片山和浩, 杉本芳一.
    • Organizer
      第31回微生物シンポジウム
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] かんきつ果汁中の新規 OATP2B1 阻害成分の探索とその阻害活性の定量的評価.2019

    • Author(s)
      森田時生, 秋好健志, 矢島広大, 今岡鮎子, 植草義徳, 木内文之, 片山和浩, 杉本芳一, 大谷壽一.
    • Organizer
      第13回次世代を担う若手医療薬科学シンポジウム
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] 上皮間葉転換によるside population細胞の誘導解析.2019

    • Author(s)
      加藤優, 片山和浩, 野口耕司, 杉本芳一.
    • Organizer
      第23回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] ABCB5発現細胞のBSO耐性機構.2019

    • Author(s)
      近藤慎吾, 片山和浩, 野口耕司, 杉本芳一.
    • Organizer
      第23回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] 上皮間葉転換に伴って誘導されるside population細胞の制御.2019

    • Author(s)
      加藤優, 近藤慎吾, 杉本芳一.
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] 癌遺伝子BCR-ABLによる統合的ストレス応答制御機構2019

    • Author(s)
      加藤優, 杉本芳一, 冨田章弘.
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] BCRPを介した3’,4’-ジメトキシフラボン類の抗がん剤耐性克服作用.2019

    • Author(s)
      恒川龍二, 片山和浩, 花屋賢悟, 東林修平, 杉本芳一, 須貝威.
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] GSK3β阻害薬によるmultipolar spindleへの効果.2019

    • Author(s)
      髙山柾, 野口耕司, 片山和浩, 杉本芳一.
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] CAGE transcriptome analysis reveals BCL2A1 upregulation in FLT3-ITD/D835 dual mutated AML cells harboring complex co-mutations.2019

    • Author(s)
      Yamatani K, Ai T, Saitoh K, Yang H, Suzuki K, Hori A, Murakami-Tonami, Y, Zhang W, Carter B, Kinjo S, Ikeo K, Katayama K, Sugimoto Y, Harada H, Miida T, Shah NP, Konopleva M, Hayashizaki Y, Andreeff M, Yoko Y.
    • Organizer
      61st ASH Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] High and low affinity kinetics of OATP2B1 - Inhibitory potency and pH-dependency of inhibitors -.2019

    • Author(s)
      Sato R, Akiyoshi T, Imaoka A, Katayama K, Sugimoto Y, Ohtani H.
    • Organizer
      日本薬物動態学会第34回年会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] FLT3-ITDによるIntegrated Stress Response の制御.2019

    • Author(s)
      佐々木大河, 加藤優, 近藤慎吾, 杉本芳一.
    • Organizer
      第63回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] P-glycoproteinの発現を制御するタンパク質の探索.2019

    • Author(s)
      在津虎次郎, 近藤慎吾, 加藤優, 片山和浩, 杉本芳一.
    • Organizer
      第63回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] ABCB5発現細胞におけるGLS発現の増大.2019

    • Author(s)
      近藤慎吾, 加藤優, 片山和浩, 杉本芳一.
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] JQ1耐性細胞の解析.2019

    • Author(s)
      齋藤優圭, 定岡健介, 近藤慎吾, 加藤優, 野口耕司, 杉本芳一.
    • Organizer
      第63回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] JQ1耐性細胞におけるcyclin E1高発現に対するTNIKの関与2019

    • Author(s)
      高橋ちひろ, 野口耕司, 石塚周平, 片山和浩, 杉本芳一.
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] ヒト有機アニオン輸送ポリペプチドOATP1A2のpH依存的輸送特性.2019

    • Author(s)
      森田時生, 秋好健志, 今岡鮎子, 片山和浩, 杉本芳一, 大谷壽一.
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] Transactivation of CD274/PD-L1 Gene Promoter by KSHV RTA/ORF50 and Cellular SP1 Proteins.2019

    • Author(s)
      Noguchi K, Miyazawa M, Katayama K, Sugimoto Y.
    • Organizer
      第67回日本ウイルス学会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] BCR-ABL tyrosine kinase inhibition induces metabolic vulnerability by preventing the integrated stress response in K562 cells.2018

    • Author(s)
      Kato K, Kunimasa K, Sugimoto Y, Tomida A.
    • Organizer
      The 23rd Japanese Foundation for Cancer Research International Symposium on Cancer Chemotherapy
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] JQ1耐性細胞におけるcyclin E1の発現上昇に対するTNIKの関与2018

    • Author(s)
      高橋ちひろ, 野口耕司, 石塚周平, 片山和浩, 杉本芳一.
    • Organizer
      第62回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] olaparib耐性細胞を用いた耐性形質の解析.2018

    • Author(s)
      野々宮悠真, 野口耕司, 片山和浩, 杉本芳一.
    • Organizer
      第22回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] IL-10プロモーターにおけるK-RTAとSP1/3の相互作用解析2018

    • Author(s)
      宮澤雅典, 野口耕司, 片山和浩, 杉本芳一.
    • Organizer
      第66回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] 患者由来胃がん細胞におけるCD44v陽性細胞の薬剤抵抗性への寄与とそのメカニズム2018

    • Author(s)
      川上隆兵, 馬島哲夫, 熊谷厚志, 杉本芳一, 右田敏郎, 佐野武, 山口研成, 清宮啓之.
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] JQ1耐性HCT 116細胞におけるTNIKの役割.2018

    • Author(s)
      野口耕司, 片山和浩, 杉本芳一.
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] テロメラーゼ阻害剤MST-312の新規作用機序とその制がん効果を規定する因子.2018

    • Author(s)
      藤原千明, 村松由起子, 矢守隆夫, 杉本芳一, 清宮啓之.
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] Poly (ADP-ribose) polymerase1 deficiency is not correlated with rucaparib and veliparib sensitivity in A2780 cells.2018

    • Author(s)
      Nonomiya Y, Noguchi K, Katayama K, Sugimoto Y.
    • Organizer
      The 30th EORTC-NCI-AACR Molecular Targets and Cancer Therapeutics Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] BCR-ABLはERストレス下におけるPERK-ATF4経路の活性化および細胞生存を制御する.2018

    • Author(s)
      加藤優, 杉本芳一, 冨田章弘.
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] HSP90 阻害薬17-AAGはFLT3-ITD/D835変異型AML細胞の増殖を抑制する.2018

    • Author(s)
      片山和浩, 野口耕司, 杉本芳一.
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] アミノ酸飢餓により引き起こされるIntegrated Stress Response選択的な阻害剤の性状解析.2018

    • Author(s)
      加藤優, 杉本芳一, 冨田章弘.
    • Organizer
      第22回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] Olaparib耐性細胞は、rucaparib、veliparibに対して感受性を示した.2018

    • Author(s)
      野々宮悠真, 野口耕司, 片山和浩, 杉本芳一.
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] Heat shock protein 90 inhibitors overcome the resistance to various Fms-like tyrosine kinase 3 inhibitors.2018

    • Author(s)
      Katayama K, Noguchi K, Sugimoto Y.
    • Organizer
      The 30th EORTC-NCI-AACR Molecular Targets and Cancer Therapeutics Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] ヒト小腸有機アニオン輸送ポリペプチド (OATP) 1A2, 2B1 の pH sensitive な輸送特性の解析.2018

    • Author(s)
      森田時生, 佐藤稜, 秋好健志, 今岡鮎子, 片山和浩, 杉本芳一, 大谷壽一.
    • Organizer
      第62回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] Quizartinib 耐性急性骨髄性白血病における分子標的としてのHSP90.2018

    • Author(s)
      片山和浩, 野口耕司, 杉本芳一.
    • Organizer
      第22回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] AKTによる染色体分離の制御.2018

    • Author(s)
      髙山柾, 野口耕司, 野々宮悠真, 片山和浩, 杉本芳一.
    • Organizer
      第62回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-18K07302
  • [Presentation] ABCB5発現細胞における基質化合物の輸送及びメタボローム解析.2017

    • Author(s)
      髙木佳奈, 近藤慎吾, 杉本芳一, 野口耕司, 片山和浩.
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台国際センター(仙台市)
    • Year and Date
      2017-03-25
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] HSP90阻害剤はquizartinib耐性細胞の増殖を抑制する.2017

    • Author(s)
      片山和浩, 野口耕司, 杉本 芳一.
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台国際センター(仙台市)
    • Year and Date
      2017-03-27
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] テロメラーゼ阻害剤 MST-312 の即時的制がん効果を規定する因子.2017

    • Author(s)
      藤原千明, 村松由起子, 矢守隆夫, 杉本芳一, 清宮啓之.
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台国際センター(仙台市)
    • Year and Date
      2017-03-27
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] PKCalphaはPim-1Lの発現を制御する.2017

    • Author(s)
      高見麻由,片山和浩, 野口耕司, 杉本 芳一.
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台国際センター(仙台市)
    • Year and Date
      2017-03-27
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] PLK阻害剤に対する薬剤感受性規定因子の探索.2017

    • Author(s)
      野々宮悠真, 野口耕司,片山和浩,杉本 芳一.
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台国際センター(仙台市)
    • Year and Date
      2017-03-25
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] 上皮間葉転換に伴って誘導される side population 細胞の性状解析2017

    • Author(s)
      徳永未来, 加藤優, 杉本芳一, 野口耕司, 片山和浩.
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台国際センター(仙台市)
    • Year and Date
      2017-03-27
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] KSHV RTAのIL-10プロモーター活性化におけるSp3結合領域の役割.2017

    • Author(s)
      宮澤雅典, 野口耕司, 片山 和浩, 杉本芳一.
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台国際センター(仙台市)
    • Year and Date
      2017-03-27
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] RSK1によるユビキチン連結酵素UBE2R1のリン酸化と抗がん剤耐性2016

    • Author(s)
      片山和浩, 野口耕司, 杉本芳一
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] AKT-Mycシグナルは、PLK阻害剤耐性に関与する.2016

    • Author(s)
      野々宮悠真, 野口耕司, 片山 和浩, 杉本芳一.
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2016-10-08
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] ABCB5はグルタチオン合成阻害薬の効果を低下させる2016

    • Author(s)
      近藤慎吾, 片山和浩, 野口耕司, 杉本芳一
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-03-28
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] Aurora kinase阻害剤が誘導する細胞分裂不全に対するAkt3の作用.2016

    • Author(s)
      野口耕司,片山和浩,杉本芳一.
    • Organizer
      第20回日本がん分子標的治療学会
    • Place of Presentation
      別府国際コンベンションセンター(別府市)
    • Year and Date
      2016-05-31
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] BET阻害剤に対する耐性メカニズムの検討2016

    • Author(s)
      石塚周平, 野口耕司, 片山和浩, 杉本芳一
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] RSK1 regulates a ubiquitin-conjugating enzyme E2 R1 that is associated with multidrug resistance in cancer cells.2016

    • Author(s)
      片山和浩, 野口耕司, 杉本芳一
    • Organizer
      Tenth AACR-JCA Joint Conference,“Breakthroughs in Cancer Research: From Basic to Therapeutics”
    • Place of Presentation
      Maui, HI, USA
    • Year and Date
      2016-02-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] FLT3-ITDのD835変異によるquizartinib耐性.2016

    • Author(s)
      伊藤賢司, 片山 和浩, 野口耕司, 杉本芳一.
    • Organizer
      第60回日本薬学会関東支部大会
    • Place of Presentation
      東京大学(東京都)
    • Year and Date
      2016-09-17
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] 大腸がん細胞株のタンキラーゼ阻害剤に対する感受性予測バイオマーカー候補因子.2016

    • Author(s)
      田中伯享, 吉田喜香, 松村由起子, 杉本芳一, 清宮啓之.
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2016-10-08
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] AktはAurora kinase阻害剤による細胞の巨核化を抑制する.2016

    • Author(s)
      針木志織, 本釜圭太, 野口耕司, 片山 和浩, 杉本芳一.
    • Organizer
      第60回日本薬学会関東支部大会
    • Place of Presentation
      東京大学(東京都)
    • Year and Date
      2016-09-17
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] P-糖タンパク質による抗がん剤耐性に対する新規治療標的としてのRSKの可能性.2016

    • Author(s)
      片山和浩,野口耕司,杉本芳一.
    • Organizer
      第20回日本がん分子標的治療学会
    • Place of Presentation
      別府国際コンベンションセンター(別府市)
    • Year and Date
      2016-05-31
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] PKCαによるPim-1L-Ser65のリン酸化の機能解析.2016

    • Author(s)
      高見麻由, 片山和浩, 野口耕司, 杉本芳一.
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2016-10-08
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] PKCαによるPim-1Lの制御2016

    • Author(s)
      高見麻由, 片山和浩, 野口耕司, 杉本芳一
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] Aurora kinase 阻害剤耐性細胞に於いて、Akt3は細胞分裂に関するKIF23を制御する.2016

    • Author(s)
      野口耕司, 片山和浩, 杉本 芳一.
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2016-10-08
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] RSKはUBE2R1の自己ユビキチン化を誘導し、P-糖タンパク質の分解を抑制する.2016

    • Author(s)
      片山和浩, 野口耕司, 杉本 芳一.
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2016-10-08
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] RTAによるIL-10プロモーター活性化に働く協調分子の同定.2016

    • Author(s)
      宮澤雅典, 野口耕司, 片山 和浩, 杉本芳一.
    • Organizer
      第60回日本薬学会関東支部大会
    • Place of Presentation
      東京大学(東京都)
    • Year and Date
      2016-09-17
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] AKT3 expression modulates chemosensitivity to aurora kinase inhibitors.2015

    • Author(s)
      野口耕司, 片山和浩, 杉本芳一
    • Organizer
      AACR-NCI-EORTC International Conference, Molecular Targets and Cancer Therapeutics
    • Place of Presentation
      Boston, MA, USA
    • Year and Date
      2015-11-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] ABCB5遺伝子導入細胞のBSO耐性機構2015

    • Author(s)
      近藤慎吾, 片山和浩, 野口耕司, 杉本芳一
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] Aurora kinase 阻害剤に対する薬剤感受性規定因子の探索2015

    • Author(s)
      野口耕司, 片山和浩, 杉本芳一
    • Organizer
      第19回日本がん分子標的治療学会
    • Place of Presentation
      松山全日空ホテル(愛媛県松山市)
    • Year and Date
      2015-06-12
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] RSKはP-糖タンパク質/ABCB1のユビキチン化酵素UBE2R1をリン酸化する2015

    • Author(s)
      片山和浩, 野口耕司, 杉本芳一
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-10
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] Plk阻害薬耐性細胞における細胞死メカニズムの変化2015

    • Author(s)
      野々宮悠真, 野口耕司, 片山和浩, 杉本芳一
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] P-糖タンパク質/ABCB1のプロテアソーム分解におけるRSKの関与2015

    • Author(s)
      片山和浩, 野口耕司, 杉本芳一
    • Organizer
      第19回日本がん分子標的治療学会
    • Place of Presentation
      松山全日空ホテル(愛媛県松山市)
    • Year and Date
      2015-06-11
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] P-glycoproteinの発現を制御するFLT3/Pim-1シグナル経路におけるprotein kinase Cの役割2015

    • Author(s)
      高見麻由, 片山和浩, 野口耕司, 杉本芳一
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] 大腸癌細胞株でのタンキラーゼ阻害剤に対する感受性規定因子2015

    • Author(s)
      田中伯享, 吉田喜香, 村松由起子, 杉本芳一, 清宮啓之
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-10
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] Aurora kinase阻害剤感受性に及ぼすAKT3の効果2015

    • Author(s)
      野口耕司, 片山和浩, 杉本芳一
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-15K14409
  • [Presentation] 抗がん剤排出トランスポーターのSNP2012

    • Author(s)
      杉本芳一
    • Organizer
      第45回制癌剤適応研究会
    • Place of Presentation
      国際ファッションセンター(東京都)(招待講演)
    • Year and Date
      2012-03-02
    • Data Source
      KAKENHI-PROJECT-23300364
  • [Presentation] Functional analysis of human ABCB52011

    • Author(s)
      Yoshikazu Sugimoto
    • Organizer
      The JSPS/iCeMS Joint International Symposium ABC 2011 in Kyoto
    • Place of Presentation
      京都大学(京都府)(招待講演)
    • Year and Date
      2011-11-17
    • Data Source
      KAKENHI-PROJECT-23300364
  • [Presentation] Multidrug resistance by P-glycoprotein and BCRP.2009

    • Author(s)
      Yoshikazu Sugimoto
    • Organizer
      The 14th Japanese Foundation for Cancer Research, International Symposium on Cancer Chemotherapy
    • Place of Presentation
      東京
    • Year and Date
      2009-12-02
    • Data Source
      KAKENHI-PROJECT-20015042
  • [Presentation] ABCトランスポーターの発現と生理活性2009

    • Author(s)
      杉本芳一
    • Organizer
      第13回日本がん分子標的治療学会学術集会
    • Place of Presentation
      徳島
    • Year and Date
      2009-06-25
    • Data Source
      KAKENHI-PROJECT-20015042
  • [Presentation] Retrovirus integration site analysis of human induced pluripotent stem (iPS) cells.2009

    • Author(s)
      Sugimoto Y
    • Organizer
      第15回日本遺伝子治療学会
    • Place of Presentation
      大阪
    • Year and Date
      2009-07-11
    • Data Source
      KAKENHI-PROJECT-20015042
  • [Presentation] ABC輸送体の遺伝子多型とがん化学療法における薬剤応答性2007

    • Author(s)
      杉本 芳一
    • Organizer
      第30回日本分子生物学会年会第80回日本生化学会大会合同年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18015045
  • [Presentation] ABC transporters and signal transduction pathways.2007

    • Author(s)
      Sugimoto Y
    • Organizer
      The 12th Japanese Foundation for Cancer Research International Symposium on Cancer Chemotherapy
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-18015045
  • [Presentation] A 5-year follow up of the patients who have undergone an MDR1 gene therapyagainst metastatic breast cancer.2007

    • Author(s)
      杉本 芳一
    • Organizer
      第13回日本遺伝子治療学会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18015045
  • [Presentation] Recent advances in anticancer agents and future prospective.2007

    • Author(s)
      杉本 芳一
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18015045
  • 1.  鶴尾 隆 (00012667)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 2.  谷口 俊一郎 (60117166)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  竹市 雅俊 (00025454)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  内藤 幹彦 (00198011)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  浜田 洋文 (00189614)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  横路 謙次郎 (70034618)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  村松 喬 (00030891)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  山本 雅 (40134621)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  丹羽 太貫 (80093293)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  桑野 信彦 (80037431)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  稲葉 実 (60085636)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  植田 和光 (10151789)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  八巻 寛 (30013329)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  河野 公俊 (00153479)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  秋山 伸一 (60117413)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  武市 紀年 (40002133)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  西條 長宏 (00215526)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  石田 良司 (50150214)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  藤田 直也 (20280951)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 20.  冨田 章弘 (40251483)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 21.  清宮 啓之 (50280623)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 22.  馬島 哲夫 (30311228)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 23.  斎藤 泉 (70158913)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  金田 安史 (10177537)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  小澤 敬也 (30137707)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  島田 隆 (20125074)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  谷 憲三朗 (00183864)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  吉田 輝彦 (10191602)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  新津 洋司郎 (10045502)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  遊佐 敬介 (30200869)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  中島 元夫
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  FUJIWARA chiaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  MURAMATSU yukiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 34.  UENO Masaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  KUNIMASA Kazuhiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 36.  AKIYOSHI Takeshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 37.  RYOUHEI Katayama
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  MIZUTANI anna
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  TANAKA noritaka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  SHOFUDA Tomoko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  野口 耕司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 11 results
  • 42.  片山 和浩
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  上野 勝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  井本 正哉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 45.  田原 栄俊
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 46.  末永 光邦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 47.  大澤 匡範
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 48.  花屋 賢悟
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 49.  大谷 壽一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 50.  岡田 洋平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 51.  金村 米博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to connect your ORCID iD to this researcher?
* This action can be performed only by the researcher themselves.

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi