Sugimoto Yoshikazu 杉本芳一

… Alternative Names

Researcher Number	10179161
Other IDs
External Links
Affiliation (Current)	2019: 慶應義塾大学, 薬学部(芝共立), 教授
Affiliation (based on the past Project Information) *help	2018: 慶應義塾大学, 薬学部(芝共立), 教授 2016: 慶應義塾大学, 薬学部(芝共立), 教授 2011 – 2015: 慶應義塾大学, 薬学部, 教授 2008 – 2009: Keio University, 薬学部, 教授 2004 – 2007: 共立薬科大学, 薬学部, 教授 … More
Review Section/Research Field	Principal Investigator Biological Sciences / Tumor therapeutics / Clinical oncology / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator ABCG2 / ABC transporter / BCRP / SNP / estrogen / ABCB1 / P-glycoprotein / がん幹細胞 / flavonoid / MDR1 … More Except Principal Investigator 抗癌剤耐性 / 耐性遺伝子 / 耐性タンパク / アドリアマイシン / ビンクリスチン / カルシウム拮抗薬 / 癌転移 / 転移と糖蛋白質 / 細胞接着分子 / 癌遺伝子 / 抗癌剤 / モノクローナル抗体 / モノクロ-ナル抗体 / DNAトポイソメラ-ゼ / 多剤耐性遺伝子 / 耐性克服 / Pー糖蛋白 / fos遺伝子 / 耐性獲得機序 / シスプラチン / メタロチオネイン / ベクター開発 / 細胞接着因子 / P-糖タンパク / グルタチオン・チオ-ル・トランスフェラ-ゼ / 遺伝子治療 / src関連遺伝子 / P‐糖タンパク / Pー糖タンパク / 耐性獲得 / ユビキチン / homing receptor / 5ーフルオロウラシル / 遺伝的不安定性 / カルシウム培抗薬 / 5ーフルオロウラシル耐性 / 転移と血小板凝集活性 / トポイソメラ-ゼ / 分子標的 / 転移 / 運動因子 / アポトーシス / アクチン / 癌移転 / 耐性克服剤開発 Less

Analysis of the resistance mechanisms to molecular-targeting anticancer agentsPrincipal InvestigatorOngoing
- Principal Investigator
  
  杉本芳一
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Keio University
Identification of factors regulating the capacity for both self-renewal and pluripotent differentiation of cancer stem cells and application to cancer treatment.Principal Investigator
- Principal Investigator
  
  Sugimoto Yoshikazu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor therapeutics
- Research Institution
  Keio University
Molecular mechanism on the drug resistance and responsiveness against anticancer agents and molecular-target agentsPrincipal Investigator
- Principal Investigator
  
  SUGIMOTO Yoshikazu
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical oncology
- Research Institution
  Keio University
トランスポーターの発現・活性の制御と機能性SNPを基盤としたがん化学療法の戦略Principal Investigator
- Principal Investigator
  
  杉本芳一
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
薬物排出トランスポーターの活性制御と機能性SNPを基盤としたがん化学療法の戦略Principal Investigator
- Principal Investigator
  
  杉本芳一
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoritsu University of Pharmacy
抗がん剤耐性の克服と機能性SNPを基盤としたがん化学療法の戦略Principal Investigator
- Principal Investigator
  
  杉本芳一
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoritsu University of Pharmacy
レトロウイルス遺伝子導入を用いた抗癌剤耐性・感受性機構の研究Principal Investigator
- Principal Investigator
  
  杉本芳一
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoritsu University of Pharmacy
  Japanese Foundation For Cancer Research
癌および正常細胞の抗癌剤感受性を規定するサプレッサー型耐性因子の同定Principal Investigator
- Principal Investigator
  
  杉本芳一
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
がん遺伝子治療ベクターの基礎研究
- Principal Investigator
  
  斎藤泉
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
がん細胞の薬剤感受性と抵抗性の分子機構とその制御
- Principal Investigator
  
  鶴尾隆
- Project Period (FY)
  1994 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
癌転移に関与する細胞側要因の解析
- Principal Investigator
  
  丹羽太貫
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hiroshima University
新しい制がん剤耐性遺伝子群の解析と克服法の確立
- Principal Investigator
  
  桑野信彦
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  大分医科大学
難治性癌の薬剤抵抗性の分子機構とその克服
- Principal Investigator
  
  鶴尾隆
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
癌転移に関与する細胞側要因の解析
- Principal Investigator
  
  横路謙次郎
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hiroshima University
新しい制がん剤耐性遺伝子群の解析と克服法の確立
- Principal Investigator
  
  桑野信彦
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  大分医科大学
難治性癌の薬剤抵抗性の分子機構とその克服
- Principal Investigator
  
  鶴尾隆
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
癌転移に関与する細胞側要因の解析
- Principal Investigator
  
  横路謙次郎
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hiroshima University
癌転移に関する基礎的研究
- Principal Investigator
  
  横路謙次郎
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hiroshima University
制がん剤耐性機構とその克服
- Principal Investigator
  
  鶴尾隆
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Japanese Foundation For Cancer Research
制がん剤耐性機構とその克服
- Principal Investigator
  
  鶴尾隆
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Japanese Foundation For Cancer Research
制がん剤耐性機構とその克服
- Principal Investigator
  
  鶴尾隆
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Japanese Foundation For Cancer Research

All 2017 2016 2015 2014 2013 2012 2011 2009 2007 2005

All Journal Article Presentation

[Journal Article] Functional Effects of AKT3 on Aurora Kinase Inhibitor-induced Aneuploidy.2017
- Author(s)
  Noguchi K, Hongama K, Hariki S, Nonomiya Y, Katayama K, Sugimoto Y.
- Journal Title
  
  J Biol Chem
  
  Volume: 292(5) Pages: 1910-1924
- DOI
  10.1074/jbc.m116.747048
- Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460076, KAKENHI-PROJECT-15K14409
[Journal Article] APC mutations as a potential biomarker for sensitivity to tankyrase inhibitors in colorectal cancer.2017
- Author(s)
  Noritaka Tanaka, Tetsuo Mashima, Anna Mizutani, Ayana Sato, Aki Aoyama, Bo Gong, Haruka Yoshida, Yukiko Muramatsu, Kento Nakata, Masaaki Matsuura, Ryohei Katayama, Satoshi Nagayama, Naoya Fujita, Yoshikazu Sugimoto, Hiroyuki Seimiya
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 16 Pages: 739-751
- DOI
  10.1158/1535-7163.mct-16-0578
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02368, KAKENHI-PROJECT-16H04715, KAKENHI-PROJECT-16H04716, KAKENHI-PROJECT-26430177, KAKENHI-PROJECT-15K14409, KAKENHI-PROJECT-15K14412
[Journal Article] RSK1 protects P-glycoprotein/ABCB1 against ubiquitin-proteasomal degradation by downregulating the ubiquitin-conjugating enzyme E2R1.2016
- Author(s)
  Katayama K, Fujiwara C, Noguchi K, Sugimoto Y.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Pages: 36134-36134
- DOI
  10.1038/srep36134
- Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460076, KAKENHI-PROJECT-15K14409
[Journal Article] Effect of AKT3 expression on MYC- and caspase-8-dependent apoptosis caused by polo-like kinase inhibitors in HCT 116 cells.2016
- Author(s)
  Nonomiya Y, Noguchi K, Tanaka N, Kasagaki T, Katayama K, Sugimoto Y.
- Journal Title
  
  Cancer Sci
  
  Volume: 107(12) Pages: 1877-1887
- DOI
  10.1111/cas.13093
- Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460076, KAKENHI-PROJECT-15K14409
[Journal Article] Cytotoxicity of the sesquiterpene lactones neoambrosin and damsin from Ambrosia maritima against multidrug-resistant cancer cells.2015
- Author(s)
  Saeed M, Jacob S, Sandjo, L, Sugimoto Y, Khalid H, Opatz T, Thines T, Efferth T
- Journal Title
  
  Front Pharmacology
  
  Volume: 6 Pages: 267-267
- DOI
  10.3389/fphar.2015.00267
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14409
[Journal Article] Activity of the dietary flavonoid, apigenin, against multidrug-resistant tumor cells as determined by pharmacogenomics and molecular docking.2015
- Author(s)
  Mohamed Saeed, Yosikazu Sugimoto, et al.
- Journal Title
  
  J Nutr Biochem
  
  Volume: VOL. 26 Pages: 44-56
- DOI
  10.1016/j.jnutbio.2014.09.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300364, KAKENHI-PROJECT-15K14409
[Journal Article] Cytotoxicity of 35 medicinal plants from Sudan towards sensitive and multidrug-resistant cancer cells.2015
- Author(s)
  Saeed ME, Abdelgadir H, Sugimoto Y, Khalid HE, Efferth T
- Journal Title
  
  J Ethnopharmacol
  
  Volume: 174 Pages: 644-658
- DOI
  10.1016/j.jep.2015.07.005
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14409
[Journal Article] Upregulation of cellular glutathione levels in human ABCB5- and murine Abcb5-transfected cells.2015
- Author(s)
  Kondo S, Hongama K, Hanaya K, Yoshida R, Kawanobe T, Katayama K, Noguchi K, Sugimoto Y
- Journal Title
  
  BMC Pharmacol Toxicol
  
  Volume: 16 Pages: 37-37
- DOI
  10.1186/s40360-015-0038-5
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460076, KAKENHI-PROJECT-15K14409
[Journal Article] Human ABC transporter ABCG2/BCRP expression in chemoresistance: basic and clinical perspectives for molecular cancer therapeutics.2014
- Author(s)
  Kohji Noguchi, Yoshikazu Sugimoto, et al.
- Journal Title
  
  Pharmacogenomics and Personalized Medicine
  
  Volume: VOL. 7 Pages: 53-64
- DOI
  10.2147/pgpm.s38295
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23300364
[Journal Article] FBXO15 regulates P-glycoprotein/ABCB1 expression through the ubiquitin-proteasome pathway in cancer cells2014
- Author(s)
  Kazuhiro Katayama, Yoshikazu Sugimoto, et al.
- Journal Title
  
  Cancer Science
  
  Volume: VOL. 345 Pages: 124-131
- DOI
  10.1016/j.canlet.2013.12.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23300364, KAKENHI-PROJECT-23590134
[Journal Article] The lignan, (-)-sesamin reveals cytotoxicity toward cancer cells: pharmacogenomic determination of genes associated with sensitivity or resistance.2014
- Author(s)
  Mohamed Saeed, Yosikazu Sugimoto, et al.
- Journal Title
  
  Phytomedicine
  
  Volume: VOL. 21 Pages: 689-696
- DOI
  10.1016/j.phymed.2014.01.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300364
[Journal Article] Regulations of P-Glycoprotein/ABCB1/MDR1 in Human Cancer Cells.2014
- Author(s)
  Kazuhiro Katayama, Yoshikazu Sugimoto, et al.
- Journal Title
  
  New Journal of Science
  
  Volume: VOL. 2014 Pages: 476974-476974
- DOI
  10.1155/2014/476974
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23300364
[Journal Article] Resistance mechanisms of cancer cells to the novel vacuolar H+-ATPase inhibitor archazolid B.2014
- Author(s)
  Rebecca Hamm, Yoshikazu Sugimoto, et al.
- Journal Title
  
  Investigational New Drugs
  
  Volume: VOL. 32 Pages: 893-903
- DOI
  10.1007/s10637-014-0134-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300364
[Journal Article] FBXO15 regulates P-glycoprotein/ABCB1 expression through the ubiquitin-proteasome pathway in cancer cells.2013
- Author(s)
  Kazuhiro Katayama, Yoshikazu Sugimoto, et al.
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Pages: 694-702
- DOI
  10.1111/cas.12145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300364, KAKENHI-PROJECT-23590134, KAKENHI-PROJECT-23790196
[Journal Article] Human Decidua-Derived Mesenchymal Cells are a Promising Source for the Generation and Cell Banking of Human Induced Pluripotent Stem Cells.2013
- Author(s)
  Tomoko Shofuda, Yoshikazu Sugimoto, et al.
- Journal Title
  
  Cell Med
  
  Volume: 4 Pages: 125-147
- DOI
  10.3727/215517912x658918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300364, KAKENHI-PROJECT-23689017, KAKENHI-PROJECT-24591538
[Journal Article] Biochemical Interaction of Anti-HCV Telaprevir with the ABC Transporters P-glycoprotein and Breast Cancer Resistance Protein2013
- Author(s)
  Yurua F, Yoshikazu Sugimoto, et al.
- Journal Title
  
  BMC Research Notes
  
  Volume: 6 Pages: 445-445
- DOI
  10.1186/1756-0500-6-445
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300364, KAKENHI-PROJECT-23590134
[Journal Article] Breast Cancer Resistance Protein (BCRP) : a Molecular Target for Anticancer Drug Resistance and Pharmacokinetics/Pharmacodynamics.2005
- Author(s)
  Sugimoto, Y.
- Journal Title
  
  Cancer Sci. 96
  
  Pages: 457-465
- Data Source
  KAKENHI-PROJECT-17016069
[Presentation] ABCB5発現細胞における基質化合物の輸送及びメタボローム解析.2017
- Author(s)
  髙木佳奈, 近藤慎吾, 杉本芳一, 野口耕司, 片山和浩.
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] テロメラーゼ阻害剤 MST-312 の即時的制がん効果を規定する因子.2017
- Author(s)
  藤原千明, 村松由起子, 矢守隆夫, 杉本芳一, 清宮啓之.
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] PKCalphaはPim-1Lの発現を制御する.2017
- Author(s)
  高見麻由,片山和浩, 野口耕司, 杉本芳一.
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] PLK阻害剤に対する薬剤感受性規定因子の探索.2017
- Author(s)
  野々宮悠真, 野口耕司,片山和浩,杉本芳一.
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] 上皮間葉転換に伴って誘導される side population 細胞の性状解析2017
- Author(s)
  徳永未来, 加藤優, 杉本芳一, 野口耕司, 片山和浩.
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] KSHV RTAのIL-10プロモーター活性化におけるSp3結合領域の役割.2017
- Author(s)
  宮澤雅典, 野口耕司, 片山和浩, 杉本芳一.
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] HSP90阻害剤はquizartinib耐性細胞の増殖を抑制する.2017
- Author(s)
  片山和浩, 野口耕司, 杉本芳一.
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] P-糖タンパク質による抗がん剤耐性に対する新規治療標的としてのRSKの可能性.2016
- Author(s)
  片山和浩，野口耕司，杉本芳一.
- Organizer
  第20回日本がん分子標的治療学会
- Place of Presentation
  別府国際コンベンションセンター（別府市）
- Year and Date
  2016-05-31
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] PKCαによるPim-1L-Ser65のリン酸化の機能解析.2016
- Author(s)
  高見麻由, 片山和浩, 野口耕司, 杉本芳一.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] ABCB5はグルタチオン合成阻害薬の効果を低下させる2016
- Author(s)
  近藤慎吾, 片山和浩, 野口耕司, 杉本芳一
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] RSK1によるユビキチン連結酵素UBE2R1のリン酸化と抗がん剤耐性2016
- Author(s)
  片山和浩, 野口耕司, 杉本芳一
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] PKCαによるPim-1Lの制御2016
- Author(s)
  高見麻由, 片山和浩, 野口耕司, 杉本芳一
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] AKT-Mycシグナルは、PLK阻害剤耐性に関与する.2016
- Author(s)
  野々宮悠真, 野口耕司, 片山和浩, 杉本芳一.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] Aurora kinase 阻害剤耐性細胞に於いて、Akt3は細胞分裂に関するKIF23を制御する.2016
- Author(s)
  野口耕司, 片山和浩, 杉本芳一.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] Aurora kinase阻害剤が誘導する細胞分裂不全に対するAkt3の作用.2016
- Author(s)
  野口耕司，片山和浩，杉本芳一.
- Organizer
  第20回日本がん分子標的治療学会
- Place of Presentation
  別府国際コンベンションセンター（別府市）
- Year and Date
  2016-05-31
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] BET阻害剤に対する耐性メカニズムの検討2016
- Author(s)
  石塚周平, 野口耕司, 片山和浩, 杉本芳一
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] RSK1 regulates a ubiquitin-conjugating enzyme E2 R1 that is associated with multidrug resistance in cancer cells.2016
- Author(s)
  片山和浩, 野口耕司, 杉本芳一
- Organizer
  Tenth AACR-JCA Joint Conference,“Breakthroughs in Cancer Research: From Basic to Therapeutics”
- Place of Presentation
  Maui, HI, USA
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] FLT3-ITDのD835変異によるquizartinib耐性.2016
- Author(s)
  伊藤賢司, 片山和浩, 野口耕司, 杉本芳一.
- Organizer
  第60回日本薬学会関東支部大会
- Place of Presentation
  東京大学（東京都）
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] RSKはUBE2R1の自己ユビキチン化を誘導し、P-糖タンパク質の分解を抑制する.2016
- Author(s)
  片山和浩, 野口耕司, 杉本芳一.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] 大腸がん細胞株のタンキラーゼ阻害剤に対する感受性予測バイオマーカー候補因子.2016
- Author(s)
  田中伯享, 吉田喜香, 松村由起子, 杉本芳一, 清宮啓之.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] RTAによるIL-10プロモーター活性化に働く協調分子の同定.2016
- Author(s)
  宮澤雅典, 野口耕司, 片山和浩, 杉本芳一.
- Organizer
  第60回日本薬学会関東支部大会
- Place of Presentation
  東京大学（東京都）
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] AktはAurora kinase阻害剤による細胞の巨核化を抑制する.2016
- Author(s)
  針木志織, 本釜圭太, 野口耕司, 片山和浩, 杉本芳一.
- Organizer
  第60回日本薬学会関東支部大会
- Place of Presentation
  東京大学（東京都）
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] 大腸癌細胞株でのタンキラーゼ阻害剤に対する感受性規定因子2015
- Author(s)
  田中伯享, 吉田喜香, 村松由起子, 杉本芳一, 清宮啓之
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] P-glycoproteinの発現を制御するFLT3/Pim-1シグナル経路におけるprotein kinase Cの役割2015
- Author(s)
  高見麻由, 片山和浩, 野口耕司, 杉本芳一
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] RSKはP-糖タンパク質／ABCB1のユビキチン化酵素UBE2R1をリン酸化する2015
- Author(s)
  片山和浩, 野口耕司, 杉本芳一
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] Plk阻害薬耐性細胞における細胞死メカニズムの変化2015
- Author(s)
  野々宮悠真, 野口耕司, 片山和浩, 杉本芳一
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] Aurora kinase阻害剤感受性に及ぼすAKT3の効果2015
- Author(s)
  野口耕司, 片山和浩, 杉本芳一
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] AKT3 expression modulates chemosensitivity to aurora kinase inhibitors.2015
- Author(s)
  野口耕司, 片山和浩, 杉本芳一
- Organizer
  AACR-NCI-EORTC International Conference, Molecular Targets and Cancer Therapeutics
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] P-糖タンパク質／ABCB1のプロテアソーム分解におけるRSKの関与2015
- Author(s)
  片山和浩, 野口耕司, 杉本芳一
- Organizer
  第19回日本がん分子標的治療学会
- Place of Presentation
  松山全日空ホテル（愛媛県松山市）
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] ABCB5遺伝子導入細胞のBSO耐性機構2015
- Author(s)
  近藤慎吾, 片山和浩, 野口耕司, 杉本芳一
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] Aurora kinase 阻害剤に対する薬剤感受性規定因子の探索2015
- Author(s)
  野口耕司, 片山和浩, 杉本芳一
- Organizer
  第19回日本がん分子標的治療学会
- Place of Presentation
  松山全日空ホテル（愛媛県松山市）
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-15K14409
[Presentation] 抗がん剤排出トランスポーターのSNP2012
- Author(s)
  杉本芳一
- Organizer
  第45回制癌剤適応研究会
- Place of Presentation
  国際ファッションセンター(東京都)(招待講演)
- Year and Date
  2012-03-02
- Data Source
  KAKENHI-PROJECT-23300364
[Presentation] Functional analysis of human ABCB52011
- Author(s)
  Yoshikazu Sugimoto
- Organizer
  The JSPS/iCeMS Joint International Symposium ABC 2011 in Kyoto
- Place of Presentation
  京都大学(京都府)(招待講演)
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-23300364
[Presentation] Multidrug resistance by P-glycoprotein and BCRP.2009
- Author(s)
  Yoshikazu Sugimoto
- Organizer
  The 14th Japanese Foundation for Cancer Research, International Symposium on Cancer Chemotherapy
- Place of Presentation
  東京
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20015042
[Presentation] Retrovirus integration site analysis of human induced pluripotent stem (iPS) cells.2009
- Author(s)
  Sugimoto Y
- Organizer
  第15回日本遺伝子治療学会
- Place of Presentation
  大阪
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-20015042
[Presentation] ABCトランスポーターの発現と生理活性2009
- Author(s)
  杉本芳一
- Organizer
  第13回日本がん分子標的治療学会学術集会
- Place of Presentation
  徳島
- Year and Date
  2009-06-25
- Data Source
  KAKENHI-PROJECT-20015042
[Presentation] ABC輸送体の遺伝子多型とがん化学療法における薬剤応答性2007
- Author(s)
  杉本芳一
- Organizer
  第30回日本分子生物学会年会第80回日本生化学会大会合同年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18015045
[Presentation] A 5-year follow up of the patients who have undergone an MDR1 gene therapyagainst metastatic breast cancer.2007
- Author(s)
  杉本芳一
- Organizer
  第13回日本遺伝子治療学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18015045
[Presentation] ABC transporters and signal transduction pathways.2007
- Author(s)
  Sugimoto Y
- Organizer
  The 12th Japanese Foundation for Cancer Research International Symposium on Cancer Chemotherapy
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-18015045
[Presentation] Recent advances in anticancer agents and future prospective.2007
- Author(s)
  杉本芳一
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18015045

1. 鶴尾隆 (00012667)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. 谷口俊一郎 (60117166)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. 竹市雅俊 (00025454)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. 内藤幹彦 (00198011)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. 浜田洋文 (00189614)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 横路謙次郎 (70034618)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. 村松喬 (00030891)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. 山本雅 (40134621)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 丹羽太貫 (80093293)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 桑野信彦 (80037431)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 稲葉実 (60085636)

# of Collaborated Projects: 2 results

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12. 植田和光 (10151789)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 八巻寛 (30013329)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 河野公俊 (00153479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 秋山伸一 (60117413)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 武市紀年 (40002133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 西條長宏 (00215526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 石田良司 (50150214)

# of Collaborated Projects: 1 results

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19. 藤田直也 (20280951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 冨田章弘 (40251483)

# of Collaborated Projects: 1 results

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21. 清宮啓之 (50280623)

# of Collaborated Projects: 1 results

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22. 馬島哲夫 (30311228)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. 斎藤泉 (70158913)

# of Collaborated Projects: 1 results

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24. 金田安史 (10177537)

# of Collaborated Projects: 1 results

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25. 小澤敬也 (30137707)

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26. 島田隆 (20125074)

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27. 谷憲三朗 (00183864)

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28. 吉田輝彦 (10191602)

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29. 新津洋司郎 (10045502)

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30. 遊佐敬介 (30200869)

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31. 中島元夫

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32. 野口耕司

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
33. 片山和浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 片山量平

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# of Collaborated Products: 1 results
35. 岡田洋平

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# of Collaborated Products: 1 results
36. 正札智子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 金村米博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sugimoto Yoshikazu 杉本 芳一

杉本 芳一 スギモト ヨシカズ

SUGIMOTO Yoshikazu 杉本 芳一

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Analysis of the resistance mechanisms to molecular-targeting anticancer agentsPrincipal InvestigatorOngoing

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Identification of factors regulating the capacity for both self-renewal and pluripotent differentiation of cancer stem cells and application to cancer treatment.Principal Investigator

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Molecular mechanism on the drug resistance and responsiveness against anticancer agents and molecular-target agentsPrincipal Investigator

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トランスポーターの発現・活性の制御と機能性SNPを基盤としたがん化学療法の戦略Principal Investigator

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薬物排出トランスポーターの活性制御と機能性SNPを基盤としたがん化学療法の戦略Principal Investigator

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抗がん剤耐性の克服と機能性SNPを基盤としたがん化学療法の戦略Principal Investigator

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レトロウイルス遺伝子導入を用いた抗癌剤耐性・感受性機構の研究Principal Investigator

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癌および正常細胞の抗癌剤感受性を規定するサプレッサー型耐性因子の同定Principal Investigator

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Sugimoto Yoshikazu 杉本芳一

杉本芳一スギモトヨシカズ

SUGIMOTO Yoshikazu 杉本芳一