KOHNO Kimitoshi 河野公俊

Researcher Number	00153479
Other IDs
Affiliation (based on the past Project Information) *help	2013 – 2014: 産業医科大学, 名誉教授, 名誉教授 2013: 産業医科大学, その他部局等, 名誉教授 2013: 産業医科大学, 医学部, 名誉教授 2012: 産業医科大学, その他部局等, 学長 1996 – 2011: School of Medicine University of Occupational and Environmental Health, Japan, Professor, 医学部, 教授 … More
Review Section/Research Field	Principal Investigator Biological Sciences / Pathological medical chemistry / Tumor biology / 代謝生物化学 / Molecular biology Except Principal Investigator General internal medicine (including Psychosomatic medicine) / 膠原病・アレルギー・感染症内科学 / Experimental pathology / 環境生理学(含体力医学･栄養生理学) / Pathological medical chemistry / Cerebral neurosurgery / Human genetics / General medical chemistry
Keywords	Principal Investigator YB-1 / p53 / シグナル伝達 / CTF / HMG1 / MDR1 / 多剤耐性遺伝子 / 酵母人工染色体 / 転写因子 / 耐性 … More Except Principal Investigator DNAトポイソメラーゼ / 薬剤耐性 / シスプラチン耐性 / 耐性克服 / 核マトリックス / 多剤耐性 / MRP / YAC / 多剤耐性遺伝子 / 耐性獲得 / DNAトポイソメラ-ゼ / 化学療法 / スーパーコイル化因子 / CPT-11 / P-糖蛋白 / トランスポーター / ABCファミリー / MDR / ディファレンシャル・ディスプレイ / 抗癌剤耐性 / ストレス科学 / 免疫系 / 酸化ストレス / ホメオサーベイランス / 膠原病 / alpha-fluoromethylhistidine / MDR1 / 血管新生 / 血管内皮細胞 / 管腔形成 / Angiogenesis / EGF / HB-EGF / IL-8 / EGFR / HSV / 体細胞遺伝変異 / 低比重リポ蛋白(LDL) / somatic cell mutants / 多剤耐性獲得 / 多剤耐性克服剤 / エトポシド耐性 / グルタチオンSートランスフェラーゼ / DNAトポイソメラーゼII / ジハイドロピリジン / Pー糖蛋白 / メタロチオネイン / グルタチオン・チオ-ル・トランスフェラ-ゼ / 5ーフルオロウラシル耐性 / ス-パ-コイル / エトポシド / がん関連遺伝子 / hst-1 / int-2増幅 / rasp21 / Ki-ras / c-myc / c-fos / p53 / がん悪性度 / 耐性マーカー / 5-フルオロウラシル耐性 / VP-16 / MST-16 / 抗がん剤耐性 / MDRI / チャンネル / YBC / ADF / チオレドキシン / レドックス / 腫瘍マーカー / チャネル / デンドライト / 樹状細胞 / 神経ペプチド / ランゲルハンス細胞 / アポトーシス / 疾患モデル動物 / 動脈硬化 / ペルオキシレドキシン / レドックス機構 / メタボリック症候群 / ヒスタミン / 膠原病学 / 抗転写因子抗体 / 転写因子 / 自己抗体 / 生存脳 / 神経伝達物資 / 免疫伝達物質 / 神経伝達物質 / 代謝系 / ストレス / リモデリング抑制 / Wnt10 / Zucker遺伝性肥満ラット / ヒスチジン脱炭酸酵素 / 神経ヒスタミン / 適応行動 / 体温調節 / エネルギー代謝 / 視床下部 / α-flnoromethylhistidine / 三叉神経中脳路核 / インターロイキン1-β / 視床下部グリコーゲン / 視床下部神経ヒスタミン代謝回転 / ヒスチジン脱炭酸酵素のmRNA発現量 / αーfluoromethylhistidine / 摂食の明暗周期消失 / 高温環境への適応行動 / 体温の恒常性維持 / 2ーdeoxyーDーglucoseによる遅発性摂食抑制 / Zuckerラット / ヒスタミン不応性 / 肥満 / 摂食行動 / 概日リズム / αーフルオロメチルヒスチジン / zucker obese rat / Histidine decarboxylase / Hypothalamic histamine / Adaptive behavior / Thermoregulation / Genetic obesity / Energy metabolism / 研究情報交換 / がん遺伝子 / ウイルス発がん / 発がんプロモーター / がん抑制遺伝子 / がん細胞 / 増殖制御 / 転写調節 / がん研究 / 研究交流 / 北米 / 研究室訪問 / 研究集会 / Information exchange / Oncogene / Tumor virus / Tumor promoter / Tumor suppressor gene / Cancer cells / Growth control / Transcriptional regulation / 制癌剤耐性 / 酵母人工染色体 / ゲノム解析 / 遺伝子増幅 / 遺伝子発現 / ヒト第7番染色体 / プロモーター / 多剤耐性遺伝子ー1 / ヒトゲノム解析 / YACベクタ- / Multi drug resistance / DNA topoisomerase / Yeastartifitial chromosome / Genome analysis / Gene amplification / Gene expression / 大網細小血管内皮細胞 / 上皮増殖因子 / 腫瘍壊死因子 / 細胞遊走 / コラーゲンゲル / ヒト大網血管内皮細胞 / 組織型プラスミノーゲンアクチベータ / トランスフォメーション増殖因子 / コラーゲン・ゲル / Endothelial cells / Human omentum microvascular endothelial cells / Epidermal growth factor / Tumor necrosis factor / Cell migration / Tubulogenesis / Collagen gel / 脳細胞移植 / 疼痛 / 遺伝子導入 / neural transplantation / intractable pain / gene engineering / プラスミノーゲン・アクチベータ / TGFα / TGFβ / TNFα / VEGF / VPF / bFGF / 血管新生因子 / Vascular endothelial cells / Plasminogen Activator / TGFalpha / TGFbeta / VEGF-VPF / TNFalpha / 抗体分子 / 標的化 / がん / 遺伝子治療 / がん治療 / 癌治療 / Antibody derivatives / Targeting / Cancer / Gene therapy / 低比重リポ蛋白 / 低比重リポ蛋白受容体 / イント(int)遺伝子 / 高コレステロ-ル血症 / コレステロ-ル代謝異常 / 0ー糖鎖不全 / 遺伝生化学 / O-糖鎖不全 / 高コレステロール血症 / LDLレセプター変異 / 細胞融合 / ゴルジ領域 / レセプター糖鎖修飾 / low density lipoprotein / low density lipoprotein receptor / int gene / hypercholesterolemia / metabolic defects of cholesterol / defective O-glycosylation / genetic-biochemistry / 低比重リポ蛋白(LDL)受容体 / 家族性高コレステロ-ル血症 / 受容体変異 / ゴルジ装置 / Oー糖鎖構造 / コレステロ-ル代謝調節 / low density lipoprotein (LDL) / LDL-receptor / familiar hypercholesterolemia / receptor mutation / Golgi apparatus / O-linked sugar chains / cholesterol metabolism Less

Functional analysis and expression of YB-1 in cancer cells, for integrated understandingPrincipal Investigator
- Principal Investigator
  
  KOHNO Kimitoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  University of Occupational and Environmental Health, Japan
Involvement of Epithelial and endothelial to mesenchymal transition in tissue remolding of rheumatic diseases
- Principal Investigator
  
  SAITO Kazuyoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health, Japan
Dynamics of stress-homeosurveillance and its relevance to disease control
- Principal Investigator
  
  TANAKA Yoshiya
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  University of Occupational and Environmental Health, Japan
A New treatment strategy using analysis of anti-transcriptional factors antibody in connective tissue diseases.
- Principal Investigator
  
  SAITO Kazuyoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health, Japan
Role of Peroxiredoxin on Metabolic Syndorome
- Principal Investigator
  
  SASAGURI Yasuyuki
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  University of Occupational and Environmental Health, Japan
Stress-surveillance and signal network originated from dendrite of various cells
- Principal Investigator
  
  TANAKA Yoshiya
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  University of Occupational and Environmental Health, Japan
Regulation for multidrug resistant cancer and cancer stem cells by ABC transporter-targeted virus
- Principal Investigator
  
  NAKANO Kenji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  The University of Tokyo
  Kurume University
Cellular responses against DNA damage and search for novel molecular targetPrincipal Investigator
- Principal Investigator
  
  KOHNO Kimitoshi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Occupational and Environmental Health, Japan
DNA障害による癌細胞応答からみた新規分子標的の探索Principal Investigator
- Principal Investigator
  
  河野公俊
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Occupational and Environmental Health, Japan
抗癌剤で誘導される遺伝子及びその転写制御を分子標的とした癌治療に向けた基礎研究Principal Investigator
- Principal Investigator
  
  河野公俊
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Occupational and Environmental Health, Japan
抗癌剤で活性化される転写因子を標的とした薬剤開発に向けた基礎研究Principal Investigator
- Principal Investigator
  
  河野公俊
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  University of Occupational and Environmental Health, Japan
Role of nuclear expression of YB-1 in cell proliferationPrincipal Investigator
- Principal Investigator
  
  KOHNO Kimitoshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Occupational and Environmental Health
DNA障害に伴う核内クロストーク及び遺伝子発現の分子機序を基盤にした治療法の開発Principal Investigator
- Principal Investigator
  
  河野公俊
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  University of Occupational and Environmental Health, Japan
腫瘍増殖と薬剤耐性を標的とした癌の遺伝子治療Principal Investigator
- Principal Investigator
  
  KOHNO Kimitoshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Molecular biology
- Research Institution
  University of Occupational and Environmental Health
抗癌剤の分子標的としての転写関連蛋白の発現機能解析と新治療法の開発Principal Investigator
- Principal Investigator
  
  河野公俊
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  University of Occupational and Environmental Health, Japan
腫瘍でのADF/チオレドキシンの活性化機構並びに抗癌剤の影響と作用機序の解析
- Principal Investigator
  
  淀井淳司
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
制癌剤の細胞内分子標的としての転写関連因子の解析Principal Investigator
- Principal Investigator
  
  河野公俊
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  University of Occupational and Environmental Health, Japan
新しいグルタチオン抱合体およびP糖蛋白型排出ポンプの構造と機能
- Principal Investigator
  
  和田守正
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
制癌剤によるアポトーシスと耐性誘導に関する分子機序Principal Investigator
- Principal Investigator
  
  河野公俊
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
新しいグルタチオン抱合体およびP糖蛋白型排出ポンプの構造と機能
- Principal Investigator
  
  和田守正
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
臨床応用可能な抗がん剤耐性マーカーの探索とその克服
- Principal Investigator
  
  桑野信彦
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
癌細胞における抗癌剤によるストレス応答を介した細胞死と耐性の分子機序Principal Investigator
- Principal Investigator
  
  河野公俊
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Joint Study on Angiogenesis and Growth Factor Responses
- Principal Investigator
  
  KUWANO Michihiko
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  KYUSHU UNIVERSITY
The Analysis of Human MDR Gene Family Using YAC Clones.Principal Investigator
- Principal Investigator
  
  KOHNO Kimitoshi
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  University of Occupational and Environmental Health
  Kyushu University
臨床応用可能な抗がん剤耐性マーカーの探索とその克服
- Principal Investigator
  
  桑野信彦
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyushu University
DNAトポイソメラーゼ機能の分子生物学的研究と癌化学療法への応用
- Principal Investigator
  
  安藤俊夫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Aichi Cancer Center Research Institute
Effects of intracerebral transplantation of genetically engineered cells to produce opiates in animal model of chronic pain
- Principal Investigator
  
  ISONO Mitsuo
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Oita Medical University
DNAトポイソメラーゼ機能の分子生物学的研究と癌化学療法への応用
- Principal Investigator
  
  安藤俊夫
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Aichi Cancer Center Research Institute
がん関連遺伝子による消化器癌悪性度の分子診断と治療への応用
- Principal Investigator
  
  斎藤貴生
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  大分医科大学
Human model system for angiogenesis and molecular mechanisms on function of growth factors involving in the angiogenesis
- Principal Investigator
  
  KUWANO Michihiko
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyushu University
  大分医科大学
DNAトポイソメラ-ゼ機能の分子生物学的研究とその癌化学療法への応用
- Principal Investigator
  
  安藤俊夫
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Aichi Cancer Center Research Institute
Information Exchange on Cancer Research with North American Countries.
- Principal Investigator
  
  YAMAGUCHI Nobuo
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Institute of Medical Science, University of Tokyo
Joint study on human genomic analysis of drug resistance
- Principal Investigator
  
  KUWANO Michihiko
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kyushu University Faculty of Medicine
  大分医科大学
新しい制がん剤耐性遺伝子群の解析と克服法の確立
- Principal Investigator
  
  桑野信彦
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  大分医科大学
Genetically obese animal : Defect in brain histamine control of adaptative function
- Principal Investigator
  
  SAKATA Oosiie
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  環境生理学(含体力医学･栄養生理学)
- Research Institution
  OITA MEDICAL UNIVERSITY
  Kyushu University
制がん剤耐性獲得の多様な分子機構と耐性克服法の開発
- Principal Investigator
  
  KUWANO Michihiko
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  大分医科大学
細胞増殖と細胞外マトリックスPrincipal Investigator
- Principal Investigator
  
  河野公俊
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  大分医科大学
Oligosaccharide Analysis of the Low Density Lipoprotein Receptors in Golgi Mutants
- Principal Investigator
  
  KUWANO Michihiko
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Oita Medical School, Faculty of Medicine
血管内皮細胞の血管構築に伴う増殖関連遺伝子及び細胞外マトリックス蛋白の発見Principal Investigator
- Principal Investigator
  
  河野公俊
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  大分医科大学
ゴルジ機能の体細胞遺伝変異と低比重リポ蛋白質(LDL)受容体の構造変化Principal Investigator
- Principal Investigator
  
  河野公俊
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  大分医科大学
Classification of human hypercholesterolemia by using somatic cell mutants with altered response to low density lipoprotein.
- Principal Investigator
  
  KUWANO Michihiko
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  General medical chemistry
- Research Institution
  Medical College of Oita

All 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

All Journal Article Presentation Book Patent

[Book] がん化学療法・分子標的治療update2009
- Author(s)
  河野公俊, 和泉弘人
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-17016075
[Journal Article] Y-box binding protein 1 expression in gastric cancer subtypes and association with cancer neovasculature2015
- Author(s)
  Wu Y, Wang KY, Li Z, Liu YP, Izumi H, Uramoto H, Nakayama Y, Ito KI, Kohno K.
- Journal Title
  
  Clinical and Translational Oncology
  
  Volume: 17 Pages: 152-159
- DOI
  10.1007/s12094-014-1208-4
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24501323
[Journal Article] Clinical Significance of Epithelial-Mesenchymal Transition-Associated Markers in Malignant Pleural Mesothelioma2014
- Author(s)
  Iwanami T, Uramoto H, Nakagawa M, Shimokawa H, Yamada S, Kohno K, Tanaka F
- Journal Title
  
  Oncology.
  
  Volume: 86(2) Pages: 109-116
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Y-box binding protein 1 enhances DNA topoisomerase 1 activity and sensitivity to camptothecin via direct interaction.2014
- Author(s)
  Wu Y, Wang KY, Li Z, Liu YP, Izumi H, Uramoto H, Nakayama Y, Ito KI, Kohno K.
- Journal Title
  
  Journal of Experimental & Clinical Cancer Research
  
  Volume: 33 Pages: 1-11
- DOI
  10.1186/s13046-014-0112-7
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24501323
[Journal Article] : Clinical Significance of Epithelial-Mesenchymal Transition-Associated Markers in Malignant Pleural Mesothelioma.2014
- Author(s)
  Iwanami T, Uramoto H, Nakagawa M, Shimokawa H, Yamada S, Kohno K, Tanaka F.
- Journal Title
  
  Oncology
  
  Volume: 86(2) Pages: 109-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Depletion of Apoptosis Signal-Regulating Kinase 1 Prevents Bile Duct Ligation-Induced Necroinflammation and Subsequent Peribiliary Fibrosis.2014
- Author(s)
  Noguchi H, Yamada S, Nabeshima A, Guo X, Tanimoto A, Wang KY, Kitada S, Tasaki T, Takama T, Shimajiri S, Horlad H, Komohara Y, Izumi H, Kohno K, Ichijo H, Sasaguri Y.
- Journal Title
  
  Am J Pathol.
  
  Volume: 184(3) Pages: 644-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Circadian Disruption and Cancer Risk : A New Concept of Stromal Niche2014
- Author(s)
  Kohno K
- Journal Title
  
  Int J Oncol
  
  Volume: 44 Pages: 364-370
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Peroxiredoxins, thioredoxin, and Y-box-binding protein-1are involved in the pathogenesis and progression of dialysis-associated renal cell carcinoma.2013
- Author(s)
  Fushimi F., Taguchi K., Izumi H., Kohno K., Kuwano M., Ono M., Nakashima Y., Takesue T., Naito S., Oda Y.
- Journal Title
  
  Virchows Arch
  
  Volume: 463 Pages: 553-562
- DOI
  10.1007/s00428-013-1460-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501323, KAKENHI-PROJECT-24650646
[Journal Article] How Occupational Health Can Contribute in a Disaster and What We Should Prepare for the Future-Lessons Learned through Support Activities of a Medical School at the Fukushima Daiichi Nuclear Power Plant in Summer 2011.2013
- Author(s)
  Mori, K., Tateishi, S., Hiraoka, K., Kubo, T., Okazaki, R., Suzuki, K., Kobayashi, Y., Kohno, K.
- Journal Title
  
  J. Occup. Health
  
  Volume: 55 Pages: 6-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Apoptosis signal-regulating kinase 1 deficiency attenuates vascular injury-induced neointimal hyperplasia by suppressing apoptosis in smooth muscle cells.2013
- Author(s)
  Tasaki T, Yamada S, Guo X, Tanimoto A, Wang KY, Nabeshima A, Kitada S, Noguchi H, Kimura S, Shimajiri S, Kohno K, Ichijo H, Sasaguri Y
- Journal Title
  
  Am J Pathol
  
  Volume: 182(2) Pages: 597-609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] PEROXIREDOXIN 4 PROTECTS AGAINST NONALCOHOLIC STEATOHEPATITIS AND TYPE 2 DIABETES IN A NONGENETIC MOUSE MODEL2013
- Author(s)
  Nabeshima A, Yamada S, Guo X, Tanimoto A, Wang KY, Shimajiri S, Kimura S, Tasaki T, Noguchi H, Kitada S, Watanabe T, Fujii J, Kohno K, Sasaguri Y.
- Journal Title
  
  Antioxid Redox Signal
  
  Volume: 19(17) Pages: 1983-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Cisplatin Resistance Associated with PARP Hyperactivation.2013
- Author(s)
  Judith Michels,Ilio Vitale,Lorenzo Galluzzi,Julien Adam,Ken Andr e Olaussen,Oliver Kepp,Laura Senovilla,Ibtissam Talhaoui,Justine Guegan,David Pierre Enot,Monique Talbot,Ang_elique Robin,Philippe Girard,C edric Or ear,Delphine Lissa,Abdul Qader Sukkurwala,Pauline Garcia,Parviz Behnam-Motlagh,Kimitoshi Kohno,et al.
- Journal Title
  
  Cancer Res
  
  Volume: 73 Pages: 2271-2280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Peroxiredoxins, thioredoxin, and Y-box-binding protein-1 are involved in the pathogenesis and progression of dialysis-associated renal cell carcinoma.2013
- Author(s)
  Fumiyoshi Fushimi, Kenichi Taguchi, Hiroto Izumi, Kimitoshi Kohno, Michihiko Kuwano, Mayumi Ono, Yutaka Nakashima, Tetsuro Takesue, Seiji Naito, Yoshinao Oda
- Journal Title
  
  Virchows Archiv
  
  Volume: 463(4) Pages: 553-562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Polypeptide N-acetylgalactosaminyl transferase 3 independently predicts high-grade tumours and poor prognosis in patients with renal cell carcinomas.2013
- Author(s)
  S Kitada, S Yamada, A Kuma, S Ouchi, T Tasaki, A Nabeshima, H Noguchi, K-Y Wang, S Shimajiri, R Nakano, H Izumi, K Kohno, T Matsumoto, Y Sasaguri.
- Journal Title
  
  British Journal of Cancer
  
  Volume: 109(2) Pages: 472-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Expression of Polypeptide N-acetylgalactosaminyl Transferase-3 and its Association with Clinicopathological Factors in Thyroid Carcinoma.2013
- Author(s)
  Mochizuki Y, Ito KI, Izumi H, Kohno K, Amano J.
- Journal Title
  
  Thyroid
  
  Volume: 23(12) Pages: 1553-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Strong YB-1 expression is associated with liver metastasis progression and predicts shorter disease-free survival in advanced gastric cancer.2012
- Author(s)
  Wu, Y., Yamada, S., Izumi, H., Li, Z., Shimajiri, S., Wang, K.Y., Liu, Y.P., Kohno, K., Sasaguri, Y
- Journal Title
  
  J. Surg. Oncol.
  
  Volume: 105(7) Pages: 724-730
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Prognostic significance of BAF57 expression in patients with endometrial carcinoma.2012
- Author(s)
  Kagami, S., Kurita, T., Kawagoe, T., Toki, N., Matsuura, Y., Hachisuga, T., Matsuyama, A., Hashimoto, H., Izumi, H., Kohno, K.
- Journal Title
  
  Histol Histopathol.
  
  Volume: 27(5) Pages: 593-599
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] New roles of Mitochondrial Transcription Factor A in Cancer2012
- Author(s)
  Yoshida, Y, Hoshino, S., Izumi, H., Kohno, K., Yamashita, Y.
- Journal Title
  
  J.phys.chem
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Overexpression of Peroxiredoxin 4 Attenuates Atherosclerosis in Apolipoprotein E Knockout Mice.2012
- Author(s)
  Guo, X., Yamada, S., Tanimoto, A., Ding, Y., Wang, K.Y., Shimajiri, S., Murata, Y., Kimura, S., Tasaki, T., Nabeshima, A., Watanabe, T., Kohno, K., Sasaguri, Y.
- Journal Title
  
  Antioxid Redox Signal.
  
  Volume: 17(10) Pages: 1362-1375
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer.2012
- Author(s)
  Kohno, K. et al.
- Journal Title
  
  Cell Rep.
  
  Volume: 2(2) Pages: 257-269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] mtTFA regulates BCL2L1 gene expression and is a prognostic factor in serous ovarian cancer2012
- Author(s)
  Kurita, T., Izumi, H., Kagami, S., Kawagoe, T., Toki, N., Matsuura, Y, Hachisuga, T., Kohno, K.
- Journal Title
  
  Cancer Sci.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Alteration of Y-box binding protein-1 expression modifies the response to endocrine therapy in estrogen receptor-positive breast cancer.2012
- Author(s)
  Ito, T., Kamijo, S., Izumi, H., Kohno, K., Amano, J., Ito, K.
- Journal Title
  
  Breast Cancer Res Treat.
  
  Volume: 133(1) Pages: 145-159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Association of Nuclear YB-1 Localization With Lung Resistance-related Protein and Epidermal Growth Factor Receptor Expression in Lung Cancer.2012
- Author(s)
  Hyogotani, A., Ito, K., Yoshida, K., Izumi, H., Kohno, K., Amano, J.
- Journal Title
  
  Clinical Lung Cancer
  
  Volume: 13 Pages: 375-384
- DOI
  10.1016/j.cllc.2011.11.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501323
[Journal Article] Clinical significance of mitochondrial transcription factor A expression in patients with colorectal cancer.2012
- Author(s)
  Nakayama, Y., Yamauchi, M., Minagawa, N., Torigoe, T., Izumi, H., Kohno, K., Yamaguchi, K.
- Journal Title
  
  Oncol. Rep.
  
  Volume: 27(5) Pages: 1325-1330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Association of Nuclear YB-1 Localization With Lung Resistance-related Protein and Epidermal Growth Factor Receptor Expression in Lung Cancer.2012
- Author(s)
  Hyogotani, A., Ito, K., Yoshida, K., Izumi, H., Kohno, K., Amano, J.
- Journal Title
  
  Clin. Lung Cancer
  
  Volume: 13(5) Pages: 375-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Strong YB-1 expression is associated with liver metastasis progression and predicts shorter disease-free survival in advanced gastric cancer.2012
- Author(s)
  Wu, Y., Yamada, S., Izumi, H., Li, Z., Shimajiri, S., Wang, K.Y., Liu, Y.P., Kohno, K., Sasaguri, Y.
- Journal Title
  
  Journal of Surgical Oncology
  
  Volume: 105 Pages: 724-730
- DOI
  10.1002/jso.23030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501323
[Journal Article] Alteration of Y-box binding protein-1 expression modifies the response to endocrine therapy in estrogen receptor-positive breast cancer.2012
- Author(s)
  Ito, T., Kamijo, S., Izumi, H., Kohno, K., Amano, J., Ito, K.
- Journal Title
  
  Breast Cancer Research and Treatment
  
  Volume: 133 Pages: 145-159
- DOI
  10.1007/s10549-011-1731-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501323
[Journal Article] Monocarboxylate transporters 1 and 4 are involved in the invasion activity of human lung cancer cells2011
- Author(s)
  Izumi, H., Takahashi, M., Uramoto, H., Nakayama, Y., Oyama, T., Wang, K.Y., Sasaguri, Y, Nishizawa, S., Kohno, K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 102 Pages: 1007-1013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Polypeptide N-acetylgalactos aminyltransferase 6 expression in pancreatic cancer is an independent prognostic factor indicating better overall survival2011
- Author(s)
  i, Z., Yamada.S., Inenaga, S., Imamura, T., Wu, Y, Wang, K.Y., Shimajiri, S., Nakano, R., Izumi, H., Kohno, K., Sasaguri, Y.
- Journal Title
  
  Br.J.Cancer
  
  Volume: 104 Pages: 1882-1889
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Human mitochondrial transcription factor A functions in both nuclei and mitochondria and regulates cancer cell growth2011
- Author(s)
  Han, B., Izumi, H., Yasuniwa, Y, Akiyama, M., Yamaguchi, T., Fujimoto, N., Matsumoto, T., Wu, B., Tanimoto, A., Sasaguri, Y., Kohno, K.
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 408 Pages: 45-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Involvement of riboflavin kinase expression in cellular sensitivity against cisplatin2011
- Author(s)
  Hirano, G., Izumi, H., Yasuniwa, Y., Shimajiri, S., Wang, K.Y., Sasaguri, Y., Kusaba, H., Matsumoto, K., Hasegawa, T., Akimoto, M., Akashi, K., Kohno, K.
- Journal Title
  
  Int.J.Oncol.
  
  Volume: 38 Pages: 893-902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Quercetin induces the expression of peroxiredoxins 3 and 5 via the Nrf2/NRF1 transcription pathway.2011
- Author(s)
  Miyamoto, N., Izumi, H., Miyamoto, R., Kondo, H., Tawara, A., Sasaguri, Y., Kohno.K.
- Journal Title
  
  Invest.Ophthalmol.Vis.Sci.
  
  Volume: 52 Pages: 1055-1063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Clinical usefulness of mitochondrial transcription factor A expression as a predictive marker in colorectal cancer patients treated with FOLFOX2011
- Author(s)
  Yoshida, Y., Hasegawa, J., Nezu, R., Kim, Y.K., Hirota, M., Kawano, K., Izumi, H., Kohno, K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 102 Pages: 578-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Quercetin induces the expression of Peroxiredoxins 3 and 5 via the Nrf2/NRF1 transcription pathway2011
- Author(s)
  Miyamoto, N., Izumi, H., Miyamoto, R., Kondo, H., Tawara, A., Sasaguri, Y., Kohno, K.
- Journal Title
  
  Invest.Ophthalmol.Vis.Sci.
  
  Volume: 52 Pages: 1055-1063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Hollingsworth, M.A. : Overexpression of GalNAc-transferase GalNAc-T3 promotes pancreatic cancer cell growth2011
- Author(s)
  Taniuchi, K., Cerny, R.L., Tanouchi, A., Kohno, K., Kotani, N., Honke, K., Saibara, T.
- Journal Title
  
  Oncogene
  
  Volume: 30 Pages: 4843-4854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Enhanced expression of nuclear factor I/B in oxaliplatin-resistant human cancer cell lines2011
- Author(s)
  Kashiwagi, E., Izumi, H., Yasuniwa, Y., Baba, R., Doi, Y., Kidani, A., Arao, T., Nishio, K., Naito, S., Kohno, K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 102 Pages: 382-386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Transcriptional regulation of activating transcription factor 4 under oxid ative stress in retinal pigment epithelial ARPE-19/HPV-16 cells2011
- Author(s)
  Miyamoto, N., Izumi, H., Bin, H., Miyamoto, R., Kondo, H., Tawara, A., Sasaguri, Y., Kohno, K.
- Journal Title
  
  Invest.Ophthalmol.Vis.Sci.
  
  Volume: 52 Pages: 1226-1234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Transcriptional regulation of activating transcription factor 4 under oxidative stress in retinal pigment epithelial ARPE-19/HPV-16 cells2011
- Author(s)
  Miyamoto, N., Izumi, H., Bin, H., Miyamoto, R., Kondo, H., Tawara, A., Sasaguri, Y., Kohno, K.
- Journal Title
  
  Invest.Ophthalmol.Vis.Sci.
  
  Volume: 52 Pages: 1226-1234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Sasaguri, Y. : Histamine Deficiency Decreases Atherosclerosis and Inflammatory Response in Apolipoprotein E Knockout Mice Independently of Serum Cholesterol Level2011
- Author(s)
  Wang, K.Y., Tanimoto, A., Guo, X., Yamada, S., Shimajiri, S., Murata, Y., Ding, Y., Tsutsui, M., Kato, S., Watanabe, T., Ohtsu, H., Hirano, K., Kohno, K.
- Journal Title
  
  ATVB
  
  Volume: 31 Pages: 800-807
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Y-box binding protein-1 is a novel molecular target for tumor vessels.2010
- Author(s)
  Takahashi M, Shimajiri S, Izumi H, Hirano G, Kashiwagi E, Yasuniwa Y, Ying W, Han B, Akiyama M, Nishizawa S, Sasaguri Y, Kohno K
- Journal Title
  
  Cancer Sci. 101
  
  Pages: 1367-1373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591179
[Journal Article] Role of ZNF 143 in tumor growth through ranscriptionalregulation of DNA replication and cell-cycle-associated genes2010
- Author(s)
  Izumi, H., Wakasugi, T., Shimajiri, S., Tanimoto, A., Sasaguri, Y., Kashiwagi, E., Yasuniwa, Y., Akiyama, M., Han, B., Wu, Y., Uchiumi, T., Arao, T., Nishio, K., Yamazaki, R., Kohno.K.
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 2538-2545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Circadian disruption accelerates tumor growth and angio/stro-magenesis through a Wnt signaling pathway.2010
- Author(s)
  Yasuniwa, Y., Izumi, H., Wang, K-Y., Shimajiri, S., Sasaguri, Y., Kawai, K., Kasai, H., Shimada, T., Miyake, K., Kashiwagi, E., Hirano, G., Kidani, A., Akiyama, M., Han, B., Wu, Y., Ieiri, I., Higuchi, S., Kohno, K.
- Journal Title
  
  PLoS ONE
  
  Volume: 5 Pages: 1-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Y-box binding protein-1 is a novel molecular target fortumor vessels.2010
- Author(s)
  Takahashi, M., Shimajiri, S., Izumi, H., Hirano, G., Kashiwagi, E., Yasuniwa, Y., Ying, W., Han, B., Akiyama, M., Nishizawa, S, Sasaguri, Y., Kohno, K.
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 1367-1373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] OVEREXPRESSION OF PEROXIREDOXIN4 PROTECTS AGAINST HIGH-DOSE STREPTOZOTOCIN-INDUCED DIABETES BY SUPPRESSING OXIDATIVE STRESS AND CYTOKINES IN TRANSGENIC MICE2010
- Author(s)
  YAN DING, 1 SOHSUKE YAMADA, 1KE-YONG WANG, 1 SHOHEI SHIMAJIRI, 1 XIN GUO, 1 AKIHIDE TANIMOTO, 2, 1 SHUJI KITAJIMA, 3 TERUO WATANABE, 4 HIROTO IZUMI, 5 KIMITOSHI KOHNO, 5 YASUYUKI SASAGURI1
- Journal Title
  
  Antioxidants & Redox Signaling (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590413
[Journal Article] N-myc downstream regulated gene 1/Cap43 suppresses tumor growth and angiogenesis of pancreatic cancer through attenuation of inhibitor ofκB kinase βexpression.2009
- Author(s)
  Hosoi, F. Izumi, H. Kohno, K, (他7名、8番目)
- Journal Title
  
  Cancer Res. 69
  
  Pages: 4983-4991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] Programmed cell death protein 4 down-regulates Y-box binding protein-1 expression via a direct interaction with Twist1 to suppress cancer cell growth.2009
- Author(s)
  Shiota, M. Izumi, H. Kohno, K., (他12名、15番目)
- Journal Title
  
  Cancer Res. 69
  
  Pages: 3148-3156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] Programmed cell death protein 4 down-regulates Y-box binding protein-1 expression via a direct interaction with Twist1 to suppress cancer cell growth.2009
- Author(s)
  Shiota, M., Izumi, H., Tanimoto, A., Takahashi, M., Miyamoto, N., Kashiwagi, E., Kidani, A., Hirano, G., Masubuchi, D., Fukunaka, Y., Yasuniwa, Y., Naito, S., Nishizawa, S., Sasaguri, Y., Kohno, K.
- Journal Title
  
  Cancer Res. 69(7)
  
  Pages: 3148-3156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016075
[Journal Article] N-myc downstream regulated gene 1/Cap43 suppresses tumor growth and angiogenesis of pancreatic cancer through attenuation of inhibitor of κB kinase β expression.2009
- Author(s)
  Hosoi, F., Izumi, H., Kohno, K, (他7名、8番目)
- Journal Title
  
  Cancer Res 69
  
  Pages: 4983-4991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] Programmed cell death protein 4 down-regulates Y-box binding protein-1 expression via a direct interaction with Twist1 to suppress cancer cell growth.2009
- Author(s)
  Shiota, M., Izumi, H., Kohno, K., (他12名、15番目)
- Journal Title
  
  Cancer Res 69
  
  Pages: 3148-3156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] Twist promotes tumor cell growth through YB-1 expression.2008
- Author(s)
  Shiota, M., Izumi, H., Onitsuka, T., Miyamoto, N., Kashiwagi, E., Kidani, A., Yokomizo, A., Naito, S., Kohno, K.
- Journal Title
  
  Cancer Res. 68(1)
  
  Pages: 98-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016075
[Journal Article] Expression of Erb2/HER2 and Estrogen receptor alpha depends upon nuclear localization of Y-box binding protein-1 in human breast cancers.2008
- Author(s)
  Fujii T, Kawahara A, Basaki Y, Hattori S, Nakashima K, Nakano K, Shirouzu K, Kohno K, Yanagawa T, Yamana H, Nishio K, Ono M, Kuwano M, Kage M
- Journal Title
  
  Cancer Res 68
  
  Pages: 1504-1512
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590315
[Journal Article] Tip60 is regulated by circadian transcription factor clock and is involved in cisplatin resistance.2008
- Author(s)
  Miyamoto, N., Izumi, H., Noguchi, T., Nakajima, Y., Ohmiya, Y., Shiota, M., Kidani, A., Tawara, A., Kohno, K.
- Journal Title
  
  J. Biol. Chem. 283(26)
  
  Pages: 18218-18226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016075
[Journal Article] Twist and p53 reciprocally regulate target genes via direct interaction.2008
- Author(s)
  Shiota, M., Izumi, H., Onitsuka, T., Miyamoto, N., Kashiwagi, E., Kidani, A., Hirano, G., Takahashi, M., Naito, S., Kohno, K.
- Journal Title
  
  Oncogene 27(42)
  
  Pages: 5543-5553
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016075
[Journal Article] Clock and ATF4 transcription system regulates drug resistance in human cancer cell lines.2007
- Author(s)
  Igarashi, T., Izumi, H., Uchiumi, T., Nishio, K., Arao, T., Tanabe, M., Uramoto, H., Sugio, K., Yasumoto, K., Sasaguri, Y., Wang, K.Y., Otsuji, Y., Kohno, K.
- Journal Title
  
  Oncogene 26(33)
  
  Pages: 4749-4760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016075
[Journal Article] ZNF143 interacts with p73 and is involved in cisplatin resistance through the transcriptional regulation of DNA repair genes.2007
- Author(s)
  Wakasugi, T., Izumi, H., Uchiumi, T., Suzuki, H., Arao, T., Nishio, K., Kohno, K.
- Journal Title
  
  Oncogene 26(36)
  
  Pages: 5194-5203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016075
[Journal Article] ZNF143 interacts with p73 and is involved in cisplatin resistance through thetranscriptional regulation of DNA repair genes2007
- Author(s)
  Wakasugi T, Izumi H, Uchiumi T, Suzuki H, Arao T, Nishio K, Kohno K
- Journal Title
  
  Oncogene 5194-203
  
  Pages: 26-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] Expression of Y-box-binding protein dbpC/contrin, a potentially new cancer/testis antigen2006
- Author(s)
  Kohno, Y.
- Journal Title
  
  Br. J. Cancer 94・5
  
  Pages: 710-716
- Data Source
  KAKENHI-PROJECT-17016075
[Journal Article] YB-1 is important for an early stage embryonic development: neural tube formation and cell proliferation.2006
- Author(s)
  Uchiumi, T., Fotovati, A., Sasaguri, T., Shibahara, K., Shimada, T., Fukuda, T., Nakamura, T., Izumi, H., Tsuzuki, T., Kuwano, M., Kohno, K.
- Journal Title
  
  J. Biol. Chem. 281(52)
  
  Pages: 40440-40449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016075
[Journal Article] Transcription factors and drug resistance.2005
- Author(s)
  Kohno, K., Uchiumi, T., Niina, I., Wakasugi, T., Igarashi, T., Momii, Y., Yoshida, T., Matsuo, K., Miyamoto, N., Izumi, H.
- Journal Title
  
  Eur. J. Cancer 41(16)
  
  Pages: 2577-2586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016075
[Journal Article] Significance of hypoxia in cervical cancer2005
- Author(s)
  Kohno, K.
- Journal Title
  
  Int.J.Clin.Oncol. 10・1
  
  Pages: 2-2
- Data Source
  KAKENHI-PROJECT-17016075
[Journal Article] Transcription factors and drug resistance2005
- Author(s)
  Kohno, K.
- Journal Title
  
  Eur.J.Cancer 41・16
  
  Pages: 2577-2586
- Data Source
  KAKENHI-PROJECT-17016075
[Journal Article] Roles of volume-sensitive Cl- channel in cisplatin-induced apoptosis in human epidermoid cancer cells.2005
- Author(s)
  Ise, T., Shimizu, T., Lee, E.L., Inoue, H., Kohno, K., Okada, Y.
- Journal Title
  
  J. Membr. Biol. 205(3)
  
  Pages: 139-145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016075
[Patent] シスプラチン耐性がんの治療のためのＨＭＧ－ＣoＡ還元酵素2014
- Inventor(s)
  河野公俊、和泉弘人
- Industrial Property Rights Holder
  河野公俊、和泉弘人
- Industrial Property Rights Type
  特許
- Filing Date
  2014-01-28
- Overseas
- Data Source
  KAKENHI-PROJECT-22249025
[Patent] シスプラチン耐性ガンの治療のためのHMG-CoA 還元酵素2014
- Inventor(s)
  河野公俊、和泉弘人
- Industrial Property Rights Holder
  河野公俊、和泉弘人
- Industrial Property Rights Type
  特許
- Filing Date
  2014-01-28
- Overseas
- Data Source
  KAKENHI-PROJECT-22249025
[Patent] 予後判定方法2009
- Inventor(s)
  松尾憲一, 山田雄次, 河野公俊
- Industrial Property Rights Holder
  大鵬薬品工業株式会社
- Acquisition Date
  2009-01-30
- Data Source
  KAKENHI-PROJECT-17016075
[Patent] 胚細胞腫瘍の検出方法2009
- Inventor(s)
  河野公俊, 笹栗靖之
- Industrial Property Rights Holder
  株式会社キューリン
- Acquisition Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-17016075
[Patent] 胚細胞腫瘍の検出方法2009
- Inventor(s)
  河野公俊, 笹栗靖之
- Industrial Property Rights Holder
  株式会社キューリン
- Acquisition Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-17016075
[Patent] 癌細胞増殖阻害方法、増殖阻害剤及びスクリーニング方法2008
- Inventor(s)
  河野公俊, 和泉弘人, 笹栗靖之
- Industrial Property Rights Holder
  産業医科大学
- Filing Date
  2008-12-26
- Overseas
- Data Source
  KAKENHI-PROJECT-17016075
[Patent] 癌細胞増殖阻害方法、増殖阻害剤及びスクリーニング方法2008
- Inventor(s)
  河野公俊, 和泉弘人, 笹栗靖之
- Industrial Property Rights Holder
  産業医科大学
- Filing Date
  2008-12-26
- Data Source
  KAKENHI-PROJECT-17016075
[Patent] ZNF 143 GENE2006
- Inventor(s)
  河野公俊他
- Industrial Property Rights Holder
  北九州TLO
- Filing Date
  2006-12-08
- Data Source
  KAKENHI-PROJECT-17016075
[Presentation] Wnt10Aはサーカディアンリズムに関連した新規腫瘍血管・間質新生因子である2010
- Author(s)
  安庭義浩・和泉弘人・笹栗靖之・河井一明・葛西宏・島田隆・三宅弘一・柏木英志・木谷昭彦・秋山正樹・韓斌・呉瑛・河野公俊
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪(大阪国際会議場、リーガロイヤルホテル大阪)
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] ATF4は網膜色素上皮細胞において、酸化ストレス下でNrf2による転写制御を受ける2010
- Author(s)
  宮本直哉・和泉弘人・宮本理恵・河野公俊・田原昭彦
- Organizer
  第114回日本眼科学会
- Place of Presentation
  名古屋(名古屋国際会議場)
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] YB-1は新しい腫瘍血管分子標的である2010
- Author(s)
  呉瑛・高橋麻由・和泉弘人・平野元・柏木英志・安庭義浩・韓斌・秋山正樹・笹栗靖之・河野公俊
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪(大阪国際会議場、リーガロイヤルホテル大阪)
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] Transcriptional regulation of activating transcription factor 4(ATF4) under oxidative stress in retinal pigment epithelial ARPE-19 cells2010
- Author(s)
  Miyamoto, N.Izumi, H.Miyamoto, R.Bin, H.Kondo, H.Tawara, A.Sasaguri, Y.Kohno, K
- Organizer
  ARVO2010
- Place of Presentation
  Florida (Greater Fort Lauderdale/Broward County Convention Center)
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] 転写因子ZNF143によるDNA複製および細胞周期関連因子の発現制御と腫瘍増殖2010
- Author(s)
  和泉弘人・柏木英志・安庭義浩・秋山正樹・Han, B.・Wu, Y.・内海健・荒尾徳三・西尾和人・河野公俊
- Organizer
  第14回日本がん分子標的治療学会学術集会
- Place of Presentation
  東京(タワーホール船堀)
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] 概日リズムの乱れは腫瘍増殖・血管新生・間質新生を引き起こす2010
- Author(s)
  安庭義浩・和泉弘人・柏木英志・平野元・木谷昭彦, Han, B.・Wu, Y.・河野公俊
- Organizer
  第14回日本がん分子標的治療学会学術集会
- Place of Presentation
  東京(タワーホール船堀)
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] 酸化ストレスと疾病2010
- Author(s)
  河野公俊
- Organizer
  第21回日本緑内障学会
- Place of Presentation
  福岡(アクロス福岡)(招待講演)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] 転写因子ZNF143によるDNA複製および細胞周期関連因子の発現制御と腫瘍増殖2010
- Author(s)
  秋山正樹・和泉弘人・柏木英志・安庭義浩・韓斌・呉瑛・内海健・荒尾徳三・西尾和人・河野公俊
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪(大阪国際会議場、リーガロイヤルホテル大阪)
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] YB-1は新しい腫瘍血管分子標的である2010
- Author(s)
  Wu, Y.・柏木英志・安庭義浩・秋山正樹, Han, B.・河野公俊
- Organizer
  第14回日本がん分子標的治療学会学術集会
- Place of Presentation
  東京(タワーホール船堀)
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] 概日リズムに制御されるがん細胞増殖と薬剤耐性2009
- Author(s)
  河野公俊
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜(パシフィコ横浜)
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-17016075
[Presentation] MCT4 expression and tumor invasion.2009
- Author(s)
  Kohno, K.
- Organizer
  First International Symposium on Proton Transport and its Inhibition (PTI) in the etiopathogenesis, diagnosis and treatment of cancer (招待講演)
- Place of Presentation
  Madrid, Spain
- Year and Date
  2009-04-28
- Data Source
  KAKENHI-PROJECT-17016075
[Presentation] MCT4 expression and tumor invasion2009
- Author(s)
  河野公俊
- Organizer
  First International Sympsium on Proton Transport and its Inhibition(PTI)in the etiopathogenesis, diagnosis and treatment of cancer
- Place of Presentation
  Madrid, Spain(The Ramon Areces Foundation)
- Year and Date
  2009-04-28
- Data Source
  KAKENHI-PROJECT-17016075
[Presentation] 概日リズムに制御されるがん細胞増殖と薬剤耐性.2009
- Author(s)
  河野公俊, 和泉弘人
- Organizer
  第32回日本分子生物学会年会(ワークショップ)
- Place of Presentation
  横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-17016075
[Presentation] 抗がん剤耐性の分子機構:基礎研究から治療研究に向けて.2008
- Author(s)
  河野公俊
- Organizer
  第60回日本泌尿器科学会西日本総会(招請講演)
- Place of Presentation
  北九州
- Year and Date
  2008-11-07
- Data Source
  KAKENHI-PROJECT-17016075
[Presentation] 転写因子と抗がん剤耐性.2007
- Author(s)
  河野公俊
- Organizer
  第16回泌尿器科分子・細胞研究会(特別講演)
- Place of Presentation
  福岡
- Year and Date
  2007-02-24
- Data Source
  KAKENHI-PROJECT-17016075
[Presentation] Cisplatin resistance and transcription factors2007
- Author(s)
  Kohno, K.
- Organizer
  The 12th Japanese Foundation for Cancer Research International Symposium on Cancer Chemotherapy
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2007-12-04
- Data Source
  KAKENHI-PROJECT-17016075
[Presentation] Cisplatin resistance and transcription factors.2007
- Author(s)
  Kohno, K., Izumi, H.
- Organizer
  The 12th Japanese Foundation for Cancer Research International Symposium on Cancer Chemotherapy (招待講演)
- Place of Presentation
  東京
- Year and Date
  2007-12-04
- Data Source
  KAKENHI-PROJECT-17016075
[Presentation] 抗がん剤耐性の分子生物学からのアプローチ.2006
- Author(s)
  河野公俊
- Organizer
  第24回日本口腔腫瘍学会総会・学術大会(特別講演)
- Place of Presentation
  福岡
- Year and Date
  2006-01-27
- Data Source
  KAKENHI-PROJECT-17016075
[Presentation] Transcription factors and cisplatin resistance.2005
- Author(s)
  Kohno, K
- Organizer
  The Japan Society for Promotion of Science (JSPS) U.S. -Japan Cooperative Cancer Research Program Seminar (招待講演)
- Place of Presentation
  大阪
- Year and Date
  2005-06-11
- Data Source
  KAKENHI-PROJECT-17016075

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KOHNO Kimitoshi 河野 公俊

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Co-Researchers

Functional analysis and expression of YB-1 in cancer cells, for integrated understandingPrincipal Investigator

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Cellular responses against DNA damage and search for novel molecular targetPrincipal Investigator

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DNA障害による癌細胞応答からみた新規分子標的の探索Principal Investigator

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抗癌剤で誘導される遺伝子及びその転写制御を分子標的とした癌治療に向けた基礎研究Principal Investigator

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抗癌剤で活性化される転写因子を標的とした薬剤開発に向けた基礎研究Principal Investigator

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Role of nuclear expression of YB-1 in cell proliferationPrincipal Investigator

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DNA障害に伴う核内クロストーク及び遺伝子発現の分子機序を基盤にした治療法の開発Principal Investigator

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腫瘍増殖と薬剤耐性を標的とした癌の遺伝子治療Principal Investigator

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KOHNO Kimitoshi 河野公俊