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SHIBUYA Masabumi  渋谷 正史

ORCIDConnect your ORCID iD *help
Researcher Number 10107427
Other IDs
Affiliation (Current) 2022: 上武大学, その他(学長), 学長
Affiliation (based on the past Project Information) *help 2009: Tokyo Medical and Dental University, 医学部, 非常勤講師
2008: Tokyo Medical and Dental University, 医学部, 客員教授
2007: Tokyo Medical and Dental University, 医学部, 非常勤講師
1990 – 2006: 東京大学, 医科学研究所, 教授
2000 – 2001: 東京大学, 医学系研究科, 教授 … More
1999: 東京大学, 医学研究科, 教授
1997: University of Tokyo, Institute of Medical Science, Professor, 医学研究所, 教授
1990: The Institute of Medical Science, The University of Tokyo, 医科学研究所・細胞遺伝学研究部, 教授
1987 – 1989: 東京大学, 医科学研究所, 助教授
1986: 東京大学, 医科学研究所・細胞遺伝学研究部, 助教授
1986: 東大, 医科学研究所, 助教授
1985: 東京大学, 医科研, 助教授 Less
Review Section/Research Field
Principal Investigator
血管生物学 / Biological Sciences / Cell biology / Experimental pathology
Except Principal Investigator
内分泌・代謝学 / Biological Sciences / Cell biology / Circulatory organs internal medicine / Hematology / Orthopaedic surgery
Keywords
Principal Investigator
シグナル伝達 / 腫瘍血管 / 脳腫瘍 / EGF受容体 / Flt受容体 / 内皮細胞増殖因子 / VEGF / VEGF受容体 / ros遺伝子 / 減数分裂 … More / cdc2 / 受容体 / Shc / チロシンキナーゼ / 血管新生 / オンコジン / チロシンキナ-ゼ / 遺伝子増幅 / 血管透過性 / C-キナーゼ / EGFR / VEGFR-1 / VEGFR / erbB遺伝子 / 28遺伝子 / Ras / cdc2@cdc28 / 精子形成 / c-myc / c-ros / 赤芽球系白血病 / CD43 / プロティンキナ-ゼ / 細胞同期 / 複合体形成 / GAP / PLCr / 内及細胞増殖因子 / 腫瘍プロモーター / KDR / がん関連遺伝子 / 受容体型チロシンキナーゼ / Flt / ノックインマウス / VEGFR-2 / がん転移 / VEGFR-2 (KDR) / VEGFR-1 (Flt-1) / VEGFR-2(KDR) / VEGFR-1(Flt-1) / 系統発生 / トランスジェニックマウス / VEGF-E / マクロファージ / 血管阻害療法 / 低酸素・低栄養ストレス / VEGFR1 / VEGFR2 / 単球 / トロンボスポンジン-1 / 血管抑制因子 / がん遺伝子 / myc遺伝子 / fps遺伝子 / ras遺伝子 / 慢性骨髄性白血病 / fms関連遺伝子 / abl遺伝子 / Flt-1 receptor / vascular endothelial growth factor / signal transduction / tumor angiogenesis / アダプター / アポトーシス / 分化 / 増殖 / EGF / 細胞増殖抑制 / p21 / tyrosine kinase / C-kinase / 腎障害 / VEGF受容体-1 / 妊娠 / 胎盤 / trophoblast stem cells / RNAi / angiogenesis / VEGF receptor / renal dysfunction … More
Except Principal Investigator
がん遺伝子 / シグナル伝達 / 移植腫瘍 / 染色体マッピング / 遺伝情報 / 化学発がん物質 / 細胞死 / 細胞増殖 / 白血病 / ペプチド合成 / がん / 分化 / がん細胞 / がん抑制遺伝子 / 単クロ-ン抗体 / コホ-ト集団 / 単クローン抗体 / コホート集団 / 細胞間相互作用 / 細胞分化 / がん転移 / ヒトがん / アポトーシス / 細胞接着 / 血管形成 / 血管新生 / ずり応力 / 酸化LDL / 細胞周期 / ウイルス発がん / Oncogene / 遺伝子治療 / Signal Transduction / VEGF / Ets-1 / FRS2 / FGF / 幹細胞 / Bmp / マウス / フレンド・ウイルス / Fvー2遺伝子 / CD43遺伝子 / 第9染色体 / G蛋白 / gp55遺伝子 / バイオサイエンス / 文部省がん研究 / 成果とりまとめ / cancer research / steering / support / project / cohort / 遺伝子 / 増殖 / 転移 / 細胞生物学 / アボトーシス / 先端的研究 / 腫瘍血管 / 薬剤耐性 / がん研究の推進 / 血管内皮細胞障害 / 血管平滑筋細胞増殖 / 動脈硬化 / マクロファージ / Shc / JNK / リン酸化 / EGF / Ras / ERK / 増殖因子 / 浸潤・転移 / 細胞外マトリックス / ヌードマウス移植癌 / ヌードマウス / 発癌 / ヒト癌遺伝子 / 活性化ras遺伝子 / マウス癌遺伝子 / ラット肝がん細胞 / mRNAの半減期 / ヌタロチオネインプロモーター / マウス赤白血病細胞 / ニワトリcーfos / アデノウイルスE4 / FeLV / 研究情報交換 / 発がんプロモーター / 増殖制御 / 転写調節 / がん研究 / 研究交流 / 北米 / 研究室訪問 / 研究集会 / Information exchange / Tumor virus / Tumor promoter / Tumor suppressor gene / Cancer cells / Growth control / Transcriptional regulation / DNA修復 / ヒトゲノム / 2国間共同研究 / cell growth / cell differentiation / apoptosis / signal transduction / cell-cell interaction / cancer metastasis / human cancer / oncogene / tumor suppressor gene / 国際学術 / 海外派遣 / 癌 / 細胞社会学 / 薬品設計 / ウイルス発癌 / 癌治療 / 化学発癌 / 情報交換 / ドラッグデザイン / 癌遺伝子治療 / 癌化学療法 / International Scientific Research / Cancer / Information Exchange / Cell Cycle / Cell Adhesion / Drug Design / Gene Therapy / ETS-1 / ES細胞 / claudin-5 / テロメラーゼ / HEX / Flt-1 / KDR / マウスES細胞 / Flk-1陽性細胞 / クローディン-5 / PECAM-1 / Flt-4 / クローディン / VEGF様遺伝子 / タイトジャンクション / SH-PTP2 / Apoptosis / ES Cell / differentiation / Claudin-5 / Telomerase / 粥状動脈硬化 / 血管内皮細胞 / 血管平滑筋細胞 / 形質転換 / 接着分子 / 脈管形成 / 遺伝子導入 / Atherosclerosis / Vascular endothelial cell / Vasculogenesis / Angiogenesis / Vascular smooth muscle cell / Phenotypic conversion / Adhesion molecule / Oxidized LDL / ドッキング分子 / 胎盤 / ノックアウトマウス / docking protein / stem cells / placenta / knock out mice / 血管新生療法 / 血管再生療法 / 再生医学 / 成長因子 / 骨髄細胞 / 内皮前駆細胞 / 血管再生 / 血管成長因子 / 再生医療 / 虚血性心疾患 / 血管透過性 / 炎症反応 / Therapeutic angiogenesis / Vascular regeneration / Regenerative medicine / Gene therapy / Growth factor / Bone marrow cells / Stem cells / Endothelial progenitor cells / 発がんプロモ-タ- / 腫瘍抗原 / T細胞の増殖 / 免疫応答 / リンフォカイン / Viral Oncogene / Tumor Promoter / Tumor Supressor Gene / Tumor Antigen / T Cell Growth / Immune Desponse / Lymphokine / 顆粒球コロニ-刺激因子 / 顆粒球コロニ-刺激因子受容体 / 骨髄性白血病 / 細胞内シグナル伝達系 / 細胞内情報伝達 / ミエロペルオキシタ-ゼ / アルカリフォスファタ-ゼ / 顆粒球 / コロニー刺激因子 / 成熟停止 / 受容体 / アルカリフォスファターゼ / Granulocyte colony-stimulating factor, / Acute Myelogenous leukemia, / Intracellular signal transduction / 02Receptor for granulocyte colony-stimulating factor, / Transforming growth factor / TGFs / TGF-β / somatomedin / 予後 / 骨肉腫 / Tnausfovwy growth 6ootor / Gowatowedin / TGFーβ / Autocrie growth 6ootor / Oute3sarome / 悪性形質発現因子 / ソマトメジン / TRANSFORMING GROWTH FACTOR (TGF) / TGF activity / Osteosarcoma / Somatomedin / TGF-B / Prognosis Less
  • Research Projects

    (41 results)
  • Research Products

    (87 results)
  • Co-Researchers

    (185 People)
  •  Signaling mechanism of tumor angiogenesis.Principal Investigator

    • Principal Investigator
      SHIBUYA Masabumi
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
      The University of Tokyo
  •  Structure and function of VEGF receptors related to preeclampsia.Principal Investigator

    • Principal Investigator
      SHIBUYA Masabumi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo
  •  Therapeutic angiogenesis using noble human VEGF-E chimeric genes and autologous bone marrow mononuclear cells

    • Principal Investigator
      MUROHARA Toyoaki
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Nagoya University
  •  Analysis of molecular mechanisms of development and physiological functions of mammals regulated by a docking protein

    • Principal Investigator
      GOTOH Noriko
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      The University of Tokyo
  •  がん研究の総合的推進に係る研究

    • Principal Investigator
      北川 知行
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Japanese Foundation For Cancer Research
  •  腫瘍の形成と維持の機構Principal Investigator

    • Principal Investigator
      渋谷 正史
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  がんの生物学的特性の研究の総括

    • Principal Investigator
      笹月 健彦, 黒木 登志夫
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyushu University
      Showa University
      The University of Tokyo
  •  がんの戦略的先端研究Principal Investigator

    • Principal Investigator
      渋谷 正史, 吉田 光昭
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  がん遺伝子の単離とヒトがんにおける異常の解明Principal Investigator

    • Principal Investigator
      渋谷 正史
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  がんの生物学的特性に関する研究の総括

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1999 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Signal transduction for cell proliferation, apoptosis and differentiation via receptor-type tyrosine kinase and Shc molecule.Principal Investigator

    • Principal Investigator
      SHIBUYA Masabumi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      The University of Tokyo
  •  受容体よりShcを介する増殖、アポトーシス、分化の情報伝達機構の解析

    • Principal Investigator
      後藤 典子
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Molecular mechanism of vascular formation

    • Principal Investigator
      SATO Yasufumi
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tohoku University
  •  動脈硬化の分子機構

    • Principal Investigator
      KITA Toru
    • Project Period (FY)
      1997 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      KYOTO UNIVERSITY
  •  動脈硬化の分子機構

    • Principal Investigator
      KITA Toru
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Kyoto University
  •  Signal Transduction of Vascular Endothelial Cell-specific Growth Factor Receptors.Principal Investigator

    • Principal Investigator
      SHIBUYA Masabumi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      The University of Tokyo
  •  内皮細胞特異的な増殖因子受容体の機能解析Principal Investigator

    • Principal Investigator
      渋谷 正史
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      血管生物学
    • Research Institution
      The University of Tokyo
  •  内皮細胞特異的な増殖因子受容体の機能解析Principal Investigator

    • Principal Investigator
      渋谷 正史
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      血管生物学
    • Research Institution
      The University of Tokyo
  •  Cooperation and information exchange with European countries.

    • Principal Investigator
      KUROKI Toshio
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Showa University
      The University of Tokyo
  •  Information Exchange on Cancer Research with North American

    • Principal Investigator
      YAMAMOTO Tadashi
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      The University of Tokyo
  •  がん遺伝子産物の作用機構と増殖シグナルの異常伝達Principal Investigator

    • Principal Investigator
      渋谷 正史
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  がん研究に要する研究資材開発

    • Principal Investigator
      黒木 登志夫
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  細胞膜受容体を介した内皮細胞の増殖制御機構Principal Investigator

    • Principal Investigator
      渋谷 正史
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      血管生物学
    • Research Institution
      The University of Tokyo
  •  がん研究に要する研究資材開発

    • Principal Investigator
      黒木 登志夫
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  がん研究に要する研究資材開発

    • Principal Investigator
      黒木 登志夫
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  がん遺伝子産物の作用機構と増殖シグナルの異常伝達Principal Investigator

    • Principal Investigator
      渋谷 正史
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Information Exchange on Cancer Research with North American Countries.

    • Principal Investigator
      YAMAGUCHI Nobuo
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Institute of Medical Science, University of Tokyo
  •  がん研究に要する研究資材開発

    • Principal Investigator
      KUROKI Toshio
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  がん遺伝子産物の機能とシグナル伝達の異常Principal Investigator

    • Principal Investigator
      渋谷 正史
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  バイオサイエンスの進展に基づくがんの重点研究

    • Principal Investigator
      豊島 久真男
    • Project Period (FY)
      1990 – 1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Friend白血病ウイルスに対する感受性を支配するマウス遺伝子の研究

    • Principal Investigator
      小高 健
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  がん遺伝子産物の機能とシグナル伝達の異常Principal Investigator

    • Principal Investigator
      渋谷 正史
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  ガン遺伝子産物の機能とシグナル伝達の異常Principal Investigator

    • Principal Investigator
      渋谷 正史
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Information Exchange on Cancer Research with North American Countries

    • Principal Investigator
      YAMAGUCHI Nobuo, 河井 貞明
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      The Institute of Medical Science, The University of Tokyo
  •  Molecular Analysis of Acute Myelogenous Leukemia Cells Using G-CSF

    • Principal Investigator
      ASANO Shigetaka
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      The Institute of Medical Science, The University of Tokyo (IMSUT)
  •  STUDY OF TRANSFORMING GROWTH FACTOR IN HUMAN OSTEOSARCOMA

    • Principal Investigator
      HIGAKI Shozo
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      TEIKYO UNIVERSITY
      The University of Tokyo
  •  化学発がん過程におけるCーmyc遺伝子活性化の関与

    • Principal Investigator
      林 健志
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  ガン遺伝子産物の機能とシグナル伝達の異常Principal Investigator

    • Principal Investigator
      渋谷 正史
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  移植人癌によって誘発されるヌードマウス腫瘍の研究

    • Principal Investigator
      玉置 憲一
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tokai University
  •  腫瘍組織におけるがん遺伝子の構造変化と発現異常Principal Investigator

    • Principal Investigator
      渋谷 正史
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      The University of Tokyo
  •  腫瘍組織におけるがん遺伝子の構造変化と発現異常Principal Investigator

    • Principal Investigator
      渋谷 正史
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      The University of Tokyo

All 2010 2009 2008 2007 2006 2005 2004

All Journal Article Presentation Book Patent

  • [Book] BMB Rep2008

    • Author(s)
      Shibuya M
    • Total Pages
      9
    • Publisher
      Vascular endothelial growth factor-dependent and-independent regulation of angiogenesis
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] VEGFR-1 signaling regulates the homing of bone marrow derived cells in a mouse stroke model.2010

    • Author(s)
      Beck H, Raab S, Copanaki E, Heil M, Scholz A, Shibuya M, Deller T, Machein M, Plate KH.
    • Journal Title

      J. Neuropathol. Exp. Neurol. 69

      Pages: 168-175

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] An FGF4-FRS2α-Cdx2 axis in trophoblast stem cells induces BMP4 to regulate proper growth of early mouse embryos.2010

    • Author(s)
      Murohashi M, Nakamura T, Tanaka S, Ichise T, Yoshida N, Yamamoto T, Shibuya M, Schlessinger J, Gotoh N.
    • Journal Title

      Stem Cells. 28

      Pages: 113-121

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] VEGFR-1 regulates adult olfactory bulb neurogenesis and migration of neural progenitors in the rostral migratory stream in vivo.2009

    • Author(s)
      Wittko IM, Schanzer A, Kuzmichev A, Schneider FT, Shibuya M, Raab S, Plate KH
    • Journal Title

      J. Neurosci. 29

      Pages: 8704-8714

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis.2009

    • Author(s)
      Kubota Y, Takubo K, Shimizu T, Ohno H, Kishi K, Shibuya M, Saya H, Suda T.
    • Journal Title

      J Exp Med. 206

      Pages: 1089-102

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Brain angiogenesis in developmental and pathological processes : therapeutic aspects of vascular endothelial growth factor2009

    • Author(s)
      Shibuya, M.
    • Journal Title

      FEBS J. 276

      Pages: 4636-4643

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Brain angiogenesis : Therapeutic aspects of VEGF2009

    • Author(s)
      Shibuya, M
    • Journal Title

      FEBS J (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Hypoxia and Low Nutrition Double Stress Induces Aggressiveness in a Murine Model of Melanoma.2009

    • Author(s)
      Osawa, T., Muramatsu, M., Watanabe, M., Shibuya, M.
    • Journal Title

      Cancer Sci. 100

      Pages: 844-851

    • NAID

      10025145482

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Professor Hidesaburo Hanafusa : A 50-Year Quest for the Molecular Basis of Cancer2009

    • Author(s)
      Shibuya, M.
    • Journal Title

      J Biochem. 146

      Pages: 3-5

    • NAID

      10025187222

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] VEGF Receptor-2 Y1175 signaling controls VEGF-induced vWF release from endothelial cells via PLCgamma1- and PKA-dependent pathways.2009

    • Author(s)
      Xiong Y, Huo Y, Chen C, Zeng H, Lu X, Wei C, Ruan C, Zhang X, Hu Z, Shibuya M, Luo J
    • Journal Title

      J Biol Chem 284

      Pages: 23217-2324

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Unique signal transduction of VEGF-A and VEGF-E2009

    • Author(s)
      Shibuya, M.
    • Journal Title

      Biochem Soc Trans. 37(Pt 6)

      Pages: 1161-1166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase.2008

    • Author(s)
      Hiratsuka S, Watanabe A, Sakurai Y, Akashi-Takamura S, Ishibashi S, Miyake K, Shibuya M, Akira S, Aburatani H, Maru Y
    • Journal Title

      Nature Cell Biol. 10

      Pages: 1349-1355

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Flt-1 signaling in macrophages promotes glioma growth in vivo.2008

    • Author(s)
      Kerber M, Reiss Y, Wickersheim A, Jugold M, Kiessling F, Heil M, Tchaikovski V, Waltenberger J, Shibuya M, Plate KH, Machein MR
    • Journal Title

      Cancer Res 68

      Pages: 7342-7351

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] VEGFR1 Tyrosine Kinase Signaling Promotes Lymphangiogenesis as Well as Angiogenesis Indirectly via Macrophage Recruitment.2008

    • Author(s)
      Murakami, M. Zheng Y, Hirashima M, Suda T, Morita Y, Ooehara J, Ema H, Fong GH, Shibuya M
    • Journal Title

      Arterioscler Thromb Vasc Biol 28

      Pages: 658-664

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation.2008

    • Author(s)
      Tammela T, Zarkada G, Wallgard E, Murtomaki A, Suchting S, Wirzenius M, Waltari M, Hellstrom M, Schomber T, Peltonen R, Freitas C, Duarte A, Isoniemi H, Laakkonen P, Christofori G, Yla-Herttuala S, Shibuya M, Pytowski B, Eichmann A, Betsholtz C, Alitalo K
    • Journal Title

      Nature 54

      Pages: 656-660

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1.2008

    • Author(s)
      Fukuhara S, Sako K, Minami T, Noda K, Kim HZ, Kodama T, Shibuya M, Takakura N, Koh GY, Mochizuki N.
    • Journal Title

      Nature Cell Biol 10

      Pages: 513-526

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting.2007

    • Author(s)
      Wirzenius, M., Tammela, T., Uutelaff, M., He, Y., Odorisio, T., Sambruno, G., Nagy, JA, Dvorak, HF, Yla-Herttuala, S., Shibuya, M., Alitalo, K
    • Journal Title

      J. Exp. Med. 204

      Pages: 1431-1340

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] A novel anti-angiogenic pathway of thrombospondin-1 mediated by suppression of the cell cycle.2007

    • Author(s)
      Yamauchi, M., Imajoh-Ohmi, S., Shibuya, M
    • Journal Title

      Cancer Science 98

      Pages: 1491-1497

    • NAID

      10019999111

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Chimeric VEGF-ENZ7/PlGF Specifically Binding to VEGFR-2 Accelerates Skin Wound Healing via Enhancement of Neovascularization.2007

    • Author(s)
      Zheng Y, Watanabe M, Kuraishi T, Hattori S, Kai C, Shibuya M
    • Journal Title

      Arterioscler, Thromb, Vasc. Biol. 27

      Pages: 503-511

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Signaling of vascular endothelial growth factor receptor-1 tyrosine kinase promotes rheumatoid arthritis through activation of monocyte/macrophages.2006

    • Author(s)
      Murakami, M., Iwai, S., Hiratsuka, S., Yamauchi, M., Nakamura, K., Iwakura, Y., Shibuya, M
    • Journal Title

      Blood 108

      Pages: 1849-1856

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Vascular endothelial growth factor receptor-1 (VEGFRl/Flt-1) : a dual regulator for angiogenesis2006

    • Author(s)
      Shibuya M.
    • Journal Title

      Angiogenesis (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390110
  • [Journal Article] Claesson-Welsh L. Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis2006

    • Author(s)
      Shibuya M.
    • Journal Title

      Exp Cell Res. 312

      Pages: 549-560

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Inhibitory Smad transcription factors protect arterial endothelial endothelial cells from apoptosis induced by BMP4.2006

    • Author(s)
      Kiyono, M., Shibuya, M
    • Journal Title

      Oncogene 25

      Pages: 7131-7137

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Vascular Endothelial Growth Factor (VEGF)-Receptor2 : Its Biological Functions, Major Signaling Pathway, and Specific Ligand VEGF-E. Endothelium2006

    • Author(s)
      Shibuya M.
    • Journal Title

      Endothelium 13

      Pages: 63-69

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390110
  • [Journal Article] Corneal avascularity is due to soluble VEGF receptor-1.2006

    • Author(s)
      Ambati BK, Nozaki M, Singh N, Takeda A, JaniPD, Suthar T, Albuquerque RJ, Richter E, Sakurai E,Newcomb MT, Kleinman ME, Caldwell RB, Lin Q,Ogura Y, Orecchia A, Samuelson DA, Agnew DW,St Leger J, Green WR, Mahasreshti PJ, Curiel DT,Kwan D, Marsh H, Ikeda S, Leiper LJ, CollinsonJM, Bogdanovich S, Khurana TS, Shibuya M,Baldwin ME, Ferrara N, Gerber HP, De Falco S,Witta J, Baffi JZ, Raisler BJ, Ambati J.
    • Journal Title

      Nature 443

      Pages: 993-997

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Vascular Endothelial Growth Factor (VEGF)-Receptor2 : Irs Biological Functions, Major Signaling Pathway, and Specific Ligand VEGF-E. Endothelium2006

    • Author(s)
      Shibuya M.
    • Journal Title

      Endothelium 13

      Pages: 63-69

    • Data Source
      KAKENHI-PROJECT-17390110
  • [Journal Article] Chimeric VEGF-ENZ7/PlGF Promotes Angiogenesis via VEGFR-2 without Significant Enhancement of Vascular Permeability and Inflammation.2006

    • Author(s)
      Zheng, Y., Murakami, M., Takahashi, H., Yamauchi, M., Kiba, A., Yamaguchi, S., Yabana, N., Alitalo, K., Shibuya, M
    • Journal Title

      Arterioscler, Thromb, Vasc. Biol. 26

      Pages: 2019-2026

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Vascular endothelial growth factor receptor-1 (VEGFR1/Flt-1) : a dual regulator for angiogenesis2006

    • Author(s)
      Shibuya M.
    • Journal Title

      Angiogenesis (in press)

    • Data Source
      KAKENHI-PROJECT-17390110
  • [Journal Article] Vascular Endothelial Growth Factor (VEGF)-Receptor2 : Its Biological Functions, Major Signaling Pathway, and Specific Ligand VEGF-E.2006

    • Author(s)
      Shibuya M.
    • Journal Title

      Endothelium. 13

      Pages: 63-69

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390110
  • [Journal Article] Signaling of vascular endothelial growth factor receptor-1 tyrosine kinase promotes rheumatoid arthritis through activation of monocyte/macrophages2006

    • Author(s)
      Murakami, M., Iwai, S., Hiratsuka, S., Yamauchi, M., Nakamura, K., Iwakura, Y., Shibuya, M.
    • Journal Title

      Blood 108

      Pages: 1849-1856

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390110
  • [Journal Article] Corneal avascularity is due to soluble VEGF receptor-1.2006

    • Author(s)
      Ambati BK, Nozaki M, Singh N, et al., Khurana TS, Shibuya M, Baldwin ME, Ferrara N, Gerber HP, De Falco S, Witta J, Baffi JZ, Raisler BJ, Ambati J.
    • Journal Title

      Nature 443

      Pages: 993-997

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390110
  • [Journal Article] Vascular endothelial growth factor receptor-1 (VEGFR1/Flt-1) : a dual regulator for angiogenesis.2006

    • Author(s)
      Shibuya, M.
    • Journal Title

      Angiogenesis 9

      Pages: 225-230

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390110
  • [Journal Article] Vascular endothelial growth factor receptor-1 signaling is essential for osteoclast development bone-marrow formation in CSF-1-deficient mice.2005

    • Author(s)
      Niida, S., Kondo, T., Hiratsuka, S., Hayashi, S.-I., Amizuka, N., Noda, T., Ikeda, K., Shibuya, M.
    • Journal Title

      Proc.Natl.Acad.Sci.U.S.A. 102

      Pages: 14016-14021

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Membrane-fixation of VEGFR1 ligand-binding domain is important for vasculogenesis/angiogenesis in mice.2005

    • Author(s)
      Hiratsuka, S., Nakao, K., Nakamura, K., Katsuki, M., Maru, Y., Shibuya, M.
    • Journal Title

      Mol.Cell.Biol. 25

      Pages: 346-354

    • Data Source
      KAKENHI-PROJECT-12215024
  • [Journal Article] Essential role of Shp2-binding sites on FRS2{alpha} for corticogenesis and for FGF2-dependent proliferation of neural progenitor cells.2005

    • Author(s)
      Yamamoto, S., Yoshino, I., Shimazaki, T., Murohashi, M., Hevner, RF., Lax, I., Okano, H., Shibuya, M., Schlessinger, J., Gotoh, N.
    • Journal Title

      Proc.Natl.Acad.Sci.U.S.A. 102

      Pages: 15983-15988

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Vascular endothelial growth factor receptor-1 signaling is essential for osteoclast development and bone-marrow formation in CSF-1-deficient mice.2005

    • Author(s)
      Niida, S., Kondo, T., Hiratsuka, S., Hayashi, S.-I., Amizuka, N., Noda, T., Ikeda, K., Shibuya, M.
    • Journal Title

      Proc.Natl.Acad.Sci.U.S.A. 102

      Pages: 14016-14021

    • Data Source
      KAKENHI-PROJECT-17390110
  • [Journal Article] Rationale for antiangiogenic cancer therapy with vaccination using epitope peptides derived from human vascular endothelial growth factor receptor 2.2005

    • Author(s)
      Wada, S., Tsunoda, T., Baba, T., Primus, J., Kuwano, H., Shibuya, M., Tahara, H.
    • Journal Title

      Cancer Res. 65

      Pages: 4939-4946

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Essential role of Flk-1 (vascular endothelial growth factor receptor-2) tyrosine residue-1173 in vasculogenesis in mice.2005

    • Author(s)
      Sakurai, Y., Ohgimoto, K., Kataoka, Y., Yoshida, N., Shibuya M
    • Journal Title

      Proc. Natl. Acad. Sci. USA 102

      Pages: 1076-1081

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Locating inositol 1,4,5-trisphosphate in the nucleus and neuronal dendrites with genetically encoded fluorescent indicators.2005

    • Author(s)
      Sato, M., Ueda, Y., Shibuya, M., Umezawa, Y.
    • Journal Title

      Anal Chem. 77

      Pages: 4751-4758

    • Data Source
      KAKENHI-PROJECT-17390110
  • [Journal Article] Membrane-fixation of VEGFR1 ligand-binding domain is important for vasculogenesis/angiogenesis in mice.2005

    • Author(s)
      Hiratsuka, S., Nakao, K., Nakamura, K., Katsuki, M., Maru, Y., Shibuya, M
    • Journal Title

      Mol. Cell. Biol. 25

      Pages: 346-354

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] The docking protein FRS2a is an essential component of multiple FGF responses during early mouse development.2005

    • Author(s)
      Gotoh, N., Manova, K., Tanaka, S., Murohashi, M., Hadari, Y., Lee, A., Hamada, Y., Hiroe, T., Ito, M., Kurihara, T., Nakazato, H., Shibuya, M., Lax, I., Lacy, E., Schlessinger, J.
    • Journal Title

      Mol.Cell.Biol. 25

      Pages: 4105-4116

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] VEGF-A is involved in guidance of VEGF-receptor-positive cells to the anterior portion of early embryos.2005

    • Author(s)
      Hiratsuka, S., Kataoka, Y., Nakao, K., Nakamura, K., Morikawa, S., Tanaka, S., Katsuki, M., Maru, Y., Shibuya, M.
    • Journal Title

      Mol.Cell.Biol. 25

      Pages: 335-363

    • Data Source
      KAKENHI-PROJECT-17390110
  • [Journal Article] VEGF-A is involved in guidance of VEGF-receptor-positive cells to the anterior portion of early embryos.2005

    • Author(s)
      Hiratsuka, S., Kataoka, Y., Nakao, K., Nakamura, K., Morikawa, S., Tanaka, S., Katsuki, M., Maru, Y., Shibuya, M.
    • Journal Title

      Mol.Cell.Biol. 25

      Pages: 355-363

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] VEGF-A is involved in guidance of VEGF-receptor-positive cells to the anterior portion of early embryos.2005

    • Author(s)
      Hiratsuka, S., Kataoka, Y., Nakao, K., Nakamura, K., Morikawa, S., Tanaka, S., Katsuki, M., Maru, Y., Shibuya, M
    • Journal Title

      Mol. Cell. Biol. 25

      Pages: 355-363

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Vascular endothelial growth factor receptor-1 signaling is essential for osteoclast development and bone-marrow formation in CSF-1-deficient mice.2005

    • Author(s)
      Niida, S., Kondo, T., Hiratsuka, S., Hayashi, S. -I., Amizuka, N., Noda, T., Ikeda, K., Shibuya, M
    • Journal Title

      Proc. Natl. Acad. Sci. USA 102

      Pages: 14016-14021

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] Rationale for antiangiogenic cancer therapy with vaccination using epitope peptides derived from human vascular endothelial growth factor receptor 2.2005

    • Author(s)
      Wada, S., Tsunoda, T., Baba, T., Primus, J., Kuwano, H., Shibuya, M., Tahara, H.
    • Journal Title

      Cancer Res. 65

      Pages: 4939-4946

    • Data Source
      KAKENHI-PROJECT-17390110
  • [Journal Article] Essential role of Flk-1 (vascular endothelial growth factor receptor-2) tyrosine residue-1173 in vasculogenesis in mice.2005

    • Author(s)
      Sakurai, Y., Ohgimoto, K., Kataoka, Y., Yoshida, N., Shibuya, M.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 102

      Pages: 1076-1081

    • Data Source
      KAKENHI-PROJECT-12215024
  • [Journal Article] Locating inositol 1,4,5-trisphosphate in the nucleus and neuronal dendrites with genetically encoded fluorescent indicators.2005

    • Author(s)
      Sato, M., Ueda, Y., Shibuya, M., Umezawa, Y.
    • Journal Title

      Anal Chem. 77

      Pages: 4751-4758

    • Data Source
      KAKENHI-PROJECT-17014020
  • [Journal Article] The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions.2005

    • Author(s)
      Takahashi H, Shibuya M.
    • Journal Title

      Clin Sci(Lond). 109

      Pages: 227-241

    • Data Source
      KAKENHI-PROJECT-17390110
  • [Journal Article] A Novel Snake Venom Vascular Endothelial Growth Factor (VEGF) Predominantly Induces Vascular Permeability through Preferential Signaling via VEGF Receptor-1.2004

    • Author(s)
      Takahashi, H., Hattori, S., Iwamatsu, A., Takizawa, H., Shibuya, M.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 46304-46314

    • Data Source
      KAKENHI-PROJECT-12215024
  • [Journal Article] The c-Cb1/CD2AP complex regulates VEGF-induced endocytosis and degradation of Flt-1 (VEGFR-1).2004

    • Author(s)
      Kobayashi, S., Sawano, A., Nojima, Y., Shibuya, M., Maru, Y.
    • Journal Title

      FASEB J. 18

      Pages: 929-931

    • Data Source
      KAKENHI-PROJECT-12215024
  • [Journal Article] Tyrosine phosphorylation sites on FRS2alpha responsible for Shp2 recruitment are critical for induction of lens and retina.2004

    • Author(s)
      Gotoh, N., Ito, M., Yamamoto, S., Yoshino, I, Song, N., Wang, Y., Lax, I., Schlessinger, J., Shibuya, M., Lang, R.A.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 101

      Pages: 17144-17149

    • Data Source
      KAKENHI-PROJECT-12215024
  • [Journal Article] Development of primitive and definitive hematopoiesis from nonhuman primate embryonic stem cells in vitro.2004

    • Author(s)
      Umeda, K., Heike, T., Yoshimoto, M., Shiota, M., Suemori, H., Luo, H.Y., Chui, D.H., Torii, R., Shibuya, M., Nakatsuji, N., Nakahata, T.
    • Journal Title

      Development 131

      Pages: 1869-1879

    • Data Source
      KAKENHI-PROJECT-12215024
  • [Patent] 骨形成因子をもちいた癌増殖抑制法2009

    • Inventor(s)
      渋谷正史、土田里香、大澤毅
    • Industrial Property Rights Holder
      東京医科歯科大学
    • Industrial Property Number
      2009-176442
    • Filing Date
      2009-07-29
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Patent] 培養血管内皮細胞株、及びそれを用いたスクリーニング方法2006

    • Inventor(s)
      渋谷 正史, 山口 幸子, 山内 麻衣
    • Industrial Property Rights Holder
      渋谷 正史
    • Industrial Property Number
      2006-071429
    • Filing Date
      2006-03-15
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] Involvement of VEGF-VEGFR System in the Progression of Cancer including Brain Tumors2009

    • Author(s)
      Shibuya, M
    • Organizer
      3rd Quandrennial Meeting of the World Federation of Neuro-Oncology
    • Place of Presentation
      Yokohama, Japan(invited speaker)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] VEGF-dependent and -independent regulation of angiogenesis2009

    • Author(s)
      Shibuya, M
    • Organizer
      KSMBMB
    • Place of Presentation
      Seoul, Korea(invited speaker)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] VEGF-dependent and -independent regulation of angiogenesis2009

    • Author(s)
      Shibuya, M
    • Organizer
      in 7th Int. Symposium on the Biology of Endothelial Cells
    • Place of Presentation
      Vienna, Austria(invited speaker)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] VEGF-dependent and -independent regulation of angiogenesis2009

    • Author(s)
      渋谷正史
    • Organizer
      7^<th> Int.Symposium on the Biology of Endothelial Cells
    • Place of Presentation
      Vienna, Austria
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] VEGF-dependent and -independent regulation of angiogenesis2009

    • Author(s)
      渋谷正史
    • Organizer
      KSMBMB
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] 血管内皮細胞の増殖シグナルとがん分子標的2009

    • Author(s)
      渋谷正史
    • Organizer
      岩手医科大学・化学療法基盤情報支援班共催シンポジウム「抗がん剤創薬の新たな展開」
    • Place of Presentation
      盛岡
    • Year and Date
      2009-01-16
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] A Unique Signal Transduction of VEGF Family Members, VEGF-A and VEGF-E.2009

    • Author(s)
      Shibuya, M
    • Organizer
      in the Int. Symposium on the Molecular and cellular mechanisms of angiogenesis
    • Place of Presentation
      Chester Univ., UK(invited speaker, plenary lecture)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] A Unique Signal Transduction of VEGF Family Members, VEGF-A and VEGF-E2009

    • Author(s)
      渋谷正史(plenary lecture)
    • Organizer
      the Int.Symposium on the Molecular and cellular mechanisms of angiogenesis
    • Place of Presentation
      Chester Univ., UK
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] Involvement of VEGF-VEGFR System in the Progression of Cancer including Brain Tumors2009

    • Author(s)
      渋谷正史
    • Organizer
      3^<rd> Quandrennial Meeting of the World Federation of Neuro-Oncology
    • Place of Presentation
      Yokohama, Japan
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] VEGFR-1 is involved in tumor-growth and metastasis including melanoma.2008

    • Author(s)
      Shibuya, M
    • Organizer
      The IPCC (International Pigment Cell Conference)-Melanoma Meeting-
    • Place of Presentation
      Sapporo(invited speaker)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] VEGF-dependent and independent regulation of angiogenesis2008

    • Author(s)
      Shibuya M
    • Organizer
      International Symposium, Vascular Differentiation and Remodeling
    • Place of Presentation
      Frankfurt, Germany
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] VEGF-dependent and-independent regulation of angiogenesis2008

    • Author(s)
      Shibuya, M.
    • Organizer
      US-Japan Cancer Research Workshop
    • Place of Presentation
      Kyoto
    • Year and Date
      2008-03-19
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] VEGFR-1 is involved in tumor-growth and metastasis including melanoma2008

    • Author(s)
      Shibuya, M
    • Organizer
      The IPCC (International Pigment Cell Conference)-Melanoma Meeting
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] VEGF-dependent and -independent regulation of angiogenesis.2008

    • Author(s)
      Shibuya, M
    • Organizer
      The US-Japan Cancer Research Workshop
    • Place of Presentation
      Kyoto(invited speaker)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] VEGF-dependent and independent regulation of angiogenesis.2008

    • Author(s)
      Shibuya, M
    • Organizer
      International Symposium, Vascular Differentiation and Remodeling
    • Place of Presentation
      Frankfurt, Germany(invited speaker)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] VEGFとその受容体による血管新生の制御2008

    • Author(s)
      渋谷正史
    • Organizer
      日本血液学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] 血管内皮増殖因子VEGFによる血管新生の分子機構2008

    • Author(s)
      渋谷正史
    • Organizer
      第2回数理医学研究会
    • Place of Presentation
      大阪
    • Year and Date
      2008-11-29
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] VEGF-dependent and independent regulation of angiogenesis2007

    • Author(s)
      Shibuya, M
    • Organizer
      The First Pacific Meeting for Angiogenesis and Lymphangiogenesis
    • Place of Presentation
      Jeju Island, Korea(invited speaker)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] VEGFR1 is involved in a variety of diseases, tumor growth/metastasis and rheumatoid arthritis.2007

    • Author(s)
      Shibuya, M
    • Organizer
      ESH EuroConference on Angiogenesis
    • Place of Presentation
      Albufeira, Portugal(invited speaker)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] VEGF-dependent and -independent regulation of angiogenesis2007

    • Author(s)
      Shibuya, M
    • Organizer
      The Joint Scientific Meeting of Vascular Biology Organization in Asia Pacific Region
    • Place of Presentation
      Tainan, Taiwan(invited speaker)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] A unique signal transduction of VEGF receptors is involved in tumor angiogenesis and metastasis2007

    • Author(s)
      Shibuya, M
    • Organizer
      Third International Conference on Tumor-stroma interaction
    • Place of Presentation
      Ascona, Switzerland(invited speaker)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] A unique signal transduction of VEGF receptors involved in tumor angiogenesis and metastasis.2007

    • Author(s)
      Shibuya, M
    • Organizer
      The 22nd Nagoya International Cancer Treatment Symposium
    • Place of Presentation
      Nagoya(invited speaker)
    • Year and Date
      2007-10-25
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] VEGF-receptor signaling, and its application for pro-angiogenic therapy2006

    • Author(s)
      Shibuya, M
    • Organizer
      ESH (European School of Hematology) Vascular Biology Meeting
    • Place of Presentation
      Cannes, France(invited speaker)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] VEGF-dependent and independent regulation of angiogenesis.2006

    • Author(s)
      Shibuya, M
    • Organizer
      20th IUBMB-Kyoto, Symposium on angiogenesis and lymphangiogenesis.
    • Place of Presentation
      Kyoto, Japan(invited speaker, chairman)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] Involvement of VEGF and its receptor system in tumor growth and metastasis.2006

    • Author(s)
      Shibuya, M
    • Organizer
      The Joint Meeting of 3rd ISC-ICCT and 11th ISCC
    • Place of Presentation
      Tokyo(invited speaker)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] Involvement of VEGFR-1 in lymphangiogenesis in vivo2006

    • Author(s)
      Shibuya, M
    • Organizer
      Gordon Research Conference on lymphangiogenesis
    • Place of Presentation
      Les Diablerets, Switzerland(invited speaker)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] VEGF signaling toward angiogenesis and vascular permeability.2006

    • Author(s)
      Shibuya, M
    • Organizer
      KCIST 2006-Vascular Biology and Human Disease
    • Place of Presentation
      Anmyondo, Korea(invited speaker)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] VEGF-receptor signaling towards angiogenesis and vascular permeability2005

    • Author(s)
      Shibuya, M
    • Organizer
      Gordon Research Conference, Angiogenesis and Microcirculation
    • Place of Presentation
      Rhod-island, USA(invited speaker)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] Novel VEGF family members define the differential signals for angiogenesis and vascular permeability2005

    • Author(s)
      Shibuya, M
    • Organizer
      ESH Angiogenesis Meeting
    • Place of Presentation
      Ascona, Switzerland(invited speaker)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] VEGF-dependent and independent regulation of angiogenesis2005

    • Author(s)
      Shibuya, M
    • Organizer
      ESH (European School of Hematology) Vascular Biology Meeting.
    • Place of Presentation
      Spain(invited speaker)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] Molecular basis of angiogenesis2005

    • Author(s)
      Shibuya, M
    • Organizer
      Korea-Japan Vascular Biology Meeting
    • Place of Presentation
      Korea(invited speaker)
    • Data Source
      KAKENHI-PROJECT-17014020
  • [Presentation] Molecular Mechanism of Angiogenesis2005

    • Author(s)
      Shibuya, M
    • Organizer
      Third European Symposium on Vascular Biology and Medicine
    • Place of Presentation
      Hamburg, Germany(invited speaker, Keynote lecture)
    • Year and Date
      2005-09-30
    • Data Source
      KAKENHI-PROJECT-17014020
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