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FUJIWARA Hiromi  藤原 大美

ORCIDConnect your ORCID iD *help
… Alternative Names

藤原 広美  フジワラ ヒロミ

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Researcher Number 70116094
Other IDs
Affiliation (based on the past Project Information) *help 2002: 大阪大学, 医学系研究科, 助教授
2001: 大阪大学, 医学研究科, 助教授
1999 – 2000: 大阪大学, 医学系研究科, 助教授
1986 – 1998: 大阪大学, 医学部, 助教授
1996: 北海道大学, バイオメディカル教育センター, 助教授 … More
1995: 大阪大学, バイオメディカル教育センター, 助教授
1995: 大阪大学, 医学部・附属バイオメディカル教育研究センター, 助教授
1994: 大阪大学, 医学部附属バイオメディカル教育研究センター, 助教授
1993: 大阪大学, 医学部・附属バイオメディカル教育研究センター, 助教授
1989: 大阪大学, 医学部・バイオメディカル教育研究センター, 助教授
1988: 大阪大, 医学部, 助教授
1988: 大阪大学, 医学部バイオメディカル教育研究センター腫瘍発, 助教授
1987: 大阪大学, 医学部附属・バイオメディカル研究教育センター, 助教授
1986: 大阪大学, 医学部・癌研・腫瘍発生学部門, 助教授
1986: Osaka Univ. Med. Sch., Inst. for Cancer Res., 医学部, 助教授 Less
Review Section/Research Field
Principal Investigator
Immunology / Biological Sciences / Functional basic dentistry
Except Principal Investigator
Biological Sciences
Keywords
Principal Investigator
免疫寛容 / 抗原提示細胞 / ヘルパーT細胞 / CD28分子 / helper T cells / 情報伝達 / co-stimulatory signal / IL-2 / IL-2レセプター / costimulation … More / interleukin-12 / インターロイキン12 / CD40 / CD40 ligand / T-APC相互作用 / インターロイキン-12 / 移植免疫 / DST / B7分子群 / interferon-2 / インターロイキン-18 / インターフエロン / MAPキシナーゼ / 転写因子 / 遺伝子発現 / T cell receptor / CD 28 / raft / cell-cell interaction / Antigen-presenting cell / rho family GTPase / 胸腺ストロ-マ細胞 / 胸腺細胞分化・増殖 / T細胞レパ-トリ- / thymic selection / T細胞増殖因子 / thymus selection / 胸腺細胞の分化成熟 / T細胞レパ-トリ-形成 / Thymic stromal cells / Iutrathymic T cell proliferation Hifferentiation / T cell repertoire / Thymic selection / T cell growth factor / 免疫抑制剤 / アロ抗原反応性T細胞 / 拒絶反応 / tolerance / transplantation immunology / immunosuppresive drugs / T細胞 / インターロイキン-12レセプター / インターフェロン-γ / インターロイキン-12産生 / T細胞増殖 / T cell / T cell actiration / interleukin-12 receptor / signal transduction / interferon-gamma / Lyt-【1^+】【2^-】T細胞 / 遅延型過敏症反応 / 主要組適合抗原 / Lyt- <1^+> <2^-> T cells / delayed-type hypersensitivity / antigen-presenting cells / major histocompatibility complex antigens / clonal deletion / ヘルパー型T細胞 / asialogly coprotein receptor / Transplantation immunity / immunologic tolerance … More
Except Principal Investigator
サイトカイン / がん遺伝子 / がん抗原 / 抗原提示細胞 / 免疫抑制 / キラーT細胞 / 抗腫瘍免疫 / 腫瘍抗原 / 分化抗原 / サイトカインレセプター / エフェクター細胞 / レトロウイルス / NK / パーフォリン / ILー2レセプター / 担癌状態 / T細胞レセプター / サイトカインネットワーク / 生体工学 / IL-12 / 癌 / Co-stimulation / IL-2レセプター / インターロイキン12 / 腫瘍免疫 / LAK細胞 / 腫瘍抗原認識機構 / 糖転移酵素 / Antisense RNA / 細胞傷害性T細胞 / ナチュラルキラー細胞 / T細胞抗原受容体 / 骨髄腫細胞 / B白血病細胞 / HVG / CD4 / ヘルパ-T細胞腫瘍 / 抗原処理機構 / 腫瘍抗原提示機構 / 腫瘍抵抗性 / トランスフレ-ス遺伝子 / アンティセンス / 熱タンパク / 内在性レトロウィルス / がん関連抗原 / サイトカイン レセプタ- / シグナル伝達機構 / エフェクタ-細胞 / T細胞 / 異常増殖 / 抗レセプタ-抗体 / チロシンリン酸化 / 担癌宿生 / TGFーβ(transforming growth factorーβ) / ヘルパ-T細胞 / CD4^+細胞 / TGFーβ / 抗腫瘍T細胞 / CD4^+T細胞 / TGF-β / 癌病態 / 産生制御 / T細胞活性化 / TCR構造異常 / HS1 / CD45 / CD28 / Syk / Jak / Co-stimulator / がん免疫 / ドレランス / NKT細胞 / 養子免疫療法 / トレランス / 免疫寛容 / MHCペプチド / T細胞エピトープ / 補助シグナル / TIL / T細胞レパトア / クラスIMHC / ペプチドモチーフ / 免疫不全 / 遺伝子発現 / シグナル伝達 / CD3結合分子 / セリン・スレオニンキナーゼ / Jak3欠損マウス / 腫瘍 / 癌悪液質 / インターロイキン6 / ヘルパーTリンパ球 / インターロイキン5 / カタラーゼ / TCR-CD_3複合体 / Srcファミリーキナーゼ / 遺伝子欠損マウス / CD45フォスファターゼ / 酸化ストレス / CTLA4 / 増殖シグナル / STAT3 / NF-IL 6 / 悪液質 / Th1 / 浸潤 / 接着 / CCR5 / CXCR3 / ケモカイン / TAK-779 / 担癌 / IFN-γ / STAT4 / ケモカインレセプター / インテグリン / マクロファージ / NK細胞 / 遅延型T細胞 / リンホカイン / T細胞因子 / IL2 / IL3 / IL4 / リンホトキシン / IL-2 / キラーT細胞活性化因子 / 癌薬物療法 / 癌免疫増強 / 細胞電気泳動 / T-T細胞相互作用 / 細胞障害性T細胞分化誘導因子 / T領域組織球 / 腫瘍内浸潤細胞 / 補体 / T-T細胞間相互作用 / Muramyl dipeptide ハプテン / 腫瘍特異免疫療法 / T細胞因子:マクロファージ / ヘルパーT細胞 / 分化・脱分極化 / 腫瘍エスケープ機構 / MRL / GVHD / Oncgene / TATA / CD2 / 腫瘍関連移植抗原 / L3T4^+T細胞 / Lyt-2^+T細胞 / 抗原提示細胞(APC) / マクロファージハイブリドーマ / マクロファージ活性化機構 / 細胞がん化 / CTL / NK骨髄腫細胞 / 慢性B白血病細胞 / セリンエステラーゼ / 自己免疫 / HTLV-1 / 自然免疫 / 腫瘍拒絶抗原 / L3L4^+細胞 / Lyt-2^+細胞 / ウイルス発がん / 発がんプロモ-タ- / がん抑制遺伝子 / T細胞の増殖 / 免疫応答 / リンフォカイン / Oncogene / Viral Oncogene / Tumor Promoter / Tumor Supressor Gene / Tumor Antigen / T Cell Growth / Immune Desponse / Lymphokine Less
  • Research Projects

    (42 results)
  • Co-Researchers

    (92 People)
  •  T細胞の副刺激情報伝達の解析と情報変換によるアポトーシス誘導Principal Investigator

    • Principal Investigator
      藤原 大美
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  腫瘍退縮に至る担がん宿主T細胞の腫瘍局所浸潤の分子機構

    • Principal Investigator
      濱岡 利之
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  IL-12の情報伝達とTh2サイトカインによる制御機構Principal Investigator

    • Principal Investigator
      藤原 大美
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  がん免疫寛容のメカニズムとその制御

    • Principal Investigator
      谷口 克
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Chiba University
  •  T細胞活性化のシグナル伝達

    • Principal Investigator
      斉藤 隆
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Chiba University
  •  サイトカインの分子制御による癌免疫治療

    • Principal Investigator
      松島 綱治
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  インターロイキン12の産生及び活性調節による免疫制御Principal Investigator

    • Principal Investigator
      藤原 大美
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  The role of interleukin-12 (IL-12) in T cell activation and IL-12 receptor-mediated signalingPrincipal Investigator

    • Principal Investigator
      FUJIWARA Hiromi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  T細胞の免疫寛容誘導とその情報伝達機構の解析Principal Investigator

    • Principal Investigator
      藤原 広美
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  T細胞活性化のシグナル伝達

    • Principal Investigator
      斉藤 隆
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Chiba University
  •  担癌宿主に於けるサイトカインネットワーク分子機構の解析

    • Principal Investigator
      松島 綱治
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kanazawa University
  •  T細胞の免疫寛容誘導とその情報伝達機構の解析Principal Investigator

    • Principal Investigator
      藤原 大美
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  T細胞活性化のシグナル伝達

    • Principal Investigator
      斉藤 隆
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Chiba University
  •  担癌宿主に於けるサイトカインネットワーク分子機構の解析

    • Principal Investigator
      松島 綱治
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kanazawa University
  •  腫瘍抗原認識の分子免疫学的解析と担癌個体のサイトカインカスケード是正の研究

    • Principal Investigator
      浜岡 利之
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  担癌宿主に於けるサイトカインネットワーク分子機構の解析

    • Principal Investigator
      松島 綱治
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kanazawa University
  •  T細胞の免疫寛容誘導とその情報伝達機構の解析Principal Investigator

    • Principal Investigator
      藤原 大美
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Tolerance induction of alloreactive T cells and regulation of graft rejectionPrincipal Investigator

    • Principal Investigator
      FUJIWARA Hiromi
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  腫瘍抗原認識の分子免疫学的解析と相癌個体のサイトカインカスケ-ド是正の研究

    • Principal Investigator
      浜岡 利之
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  がん抗原の発現調節と免疫系による認識

    • Principal Investigator
      谷口 克
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Chiba University
  •  エフェクタ-細胞の機能分化:サイトカインとそのレセプタ-系を中心にしたアプロ-チ

    • Principal Investigator
      高津 聖志
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  腫瘍抗原認識の分子免疫学的解析と担癌個体のサイトカインカスケ-ド是正の研究

    • Principal Investigator
      浜岡 利之
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  エフェクター細胞の機能分化;サイトカインとそのレセプター系を中心としたアプローチ

    • Principal Investigator
      高津 聖志
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  宿主側からみた腫瘍増殖機序の分子免疫学的解析

    • Principal Investigator
      奥村 康
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Juntendo University
  •  腫瘍免疫の抗原認識機構の解析と人為的制御

    • Principal Investigator
      HAMAOKA Toshiyuki
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Analyses of T Cell Proliferation/Differentiation and Repertoire Selection in the thy UsusPrincipal Investigator

    • Principal Investigator
      FUJIWARA Hiromi
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Osaka University Medical School
  •  がん抗原の発現調節と免疫系による認識

    • Principal Investigator
      谷口 克
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Chiba University
  •  がん抗原の発現調節と免疫系による認識

    • Principal Investigator
      谷口 克
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Chiba University
  •  エフェクター細胞の機能分化:サイトカインとそのレセプター系を中心にしたアプローチ

    • Principal Investigator
      高津 聖志
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  腫瘍免疫の抗原認識機構の解析と人為的制御

    • Principal Investigator
      浜岡 利之
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Information Exchange on Cancer Research with North American Countries

    • Principal Investigator
      YAMAGUCHI Nobuo, 河井 貞明
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      The Institute of Medical Science, The University of Tokyo
  •  宿主側から見た腫瘍増殖機序の分子免疫学的解析

    • Principal Investigator
      奥村 康
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Juntendo University
  •  腫瘍免疫の抗原認識機構の解析と人為的制御

    • Principal Investigator
      浜岡 利之
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Tolerance induction of alloantigen-reactive T cells and analysis of its immunologic and cell-biologic mechanismsPrincipal Investigator

    • Principal Investigator
      FUJIWARA Hiromi
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Osaka University
  •  T細胞因子による抗腫瘍免疫の調節機構に関する研究

    • Principal Investigator
      熊谷 勝男
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tohoku University
  •  腫瘍関連移植抗原に対する免疫応答の細胞性及び分子機構の解析とその応用

    • Principal Investigator
      浜岡 利之
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Osaka University
  •  T細胞因子による抗腫瘍免疫の調節機構に関する研究

    • Principal Investigator
      熊谷 勝男
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tohoku University
  •  宿主側から見た腫瘍増殖機序の分子免疫学的解析

    • Principal Investigator
      奥村 康
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Juntendo University
  •  腫瘍抗原の発現と免疫系の認識に関する分子免疫学的解析

    • Principal Investigator
      谷口 克
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Chiba University
  •  腫瘍抗原の発現と免疫系の認識に関する分子免疫学的解析

    • Principal Investigator
      谷口 克
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Chiba University
  •  Studies on the analysis of antigen recognition mechanisms of Lyt- <1^+> <2^-> T cells mediating in vivo cell-mediated immunity and the regulation of induction of these cells.Principal Investigator

    • Principal Investigator
      FUJIWARA Hiromi
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  癌薬物療法におけるエフェクター・サプレッサーバランスのバイオダイナミクス

    • Principal Investigator
      新田 和男
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  • 1.  HAMAOKA Toshiyuki (60028529)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 2.  SUGAMURA Kazuo (20117360)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  谷口 克 (80110310)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  UEDE Toshimitsu (00160185)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  熊谷 勝男 (00005018)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  栗林 景容 (10064578)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 7.  奥村 康 (50009700)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 8.  佐藤 昇志 (50158937)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 9.  松島 綱治 (50222427)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 10.  審良 静男 (50192919)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 11.  細川 真澄男 (20001901)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 12.  竹森 利忠 (60114295)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  松岡 雄治 (70078773)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 14.  高津 聖志 (10107055)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 15.  吉永 秀 (90040196)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 16.  平野 俊夫 (40136718)
    # of Collaborated Projects: 3 results
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  • 91.  高井 康之 (10216608)
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  • 92.  朴 曽夾
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