kishihara kenji 岸原健二

… Alternative Names

Researcher Number	80214774
Other IDs
Affiliation (Current)	2019: 長崎国際大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2008 – 2010: Nagasaki International University, 薬学部, 教授 2007: The University of Tokushima, Institute of Health Biosciences, Graduate School, Associate Professor 2005 – 2006: 徳島大学, 大学院ヘルスバイオサイエンス研究部, 助教授 2004 – 2005: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教授 2004: 徳島大学, ヘルスバイオサイエンス研究部, 助教授 … More
Review Section/Research Field	Principal Investigator Immunology / Immunology Except Principal Investigator Surgical dentistry / Biological Sciences / Thoracic surgery / Kidney internal medicine / 寄生虫学(含医用動物学)
Keywords	Principal Investigator ジーンターゲティング / CD45 / Notch / リンパ球 / チロシンホスファターゼ / γδT細胞 / T細胞 / NK細胞 / 免疫異常 / PCR … More Except Principal Investigator T細胞レセプター / Cytokine / T cell receptor / サイトカイン / 免疫 / 遺伝子クローニング / 口腔扁平上皮癌 / T細胞 / ノックアウトマウス / Gene cloning / 癌 / 細胞障害性T細胞 / Tumor-associated antigen / Tリンパ球 / Immunology / 腫瘍関連抗原 / CD8 / シグナル伝達 / Knockout mouse / Notch / Co-stimulation / Oral squamous cell carcinoma / 尿細管間質障害 / TCR構造異常 / 細胞性免疫 / テストステロン / Jak / T細胞クローン / CD4 and CD8 knockout mice / 増殖シグナル / シェーグレン症候群 / TCR-CD_3複合体 / 大腸炎 / CD8+T細胞 / xenografts / ネズミ糞線虫 / シェーグレン症侯群 / 増殖因子 / Macrophage / 免疫学 / CD28 / Discordant異種移植 / HS1 / 腫瘍免疫 / JAK / 細胞分化 / 排虫 / 臨床検査 / Antigen / Sjogren's syndrome / CD8+T cell / CD3結合分子 / Strongyloides ratti / CD45フォスファターゼ / 細胞系譜決定 / Tubulointerstitial damage / STAT / キメラ / discordant / 細胞内寄生性病原体 / Cellular immunity / 抗腫瘍免疫 / 発生・分化 / Cytotoxic T cell / 細胞・組織 / 関節炎リウマチ / 遺伝子欠損マウス / skin graft / 炎症性疾患 / Ras / CTLA4 / 造血因子 / 細胞傷害性T細胞 / ワクチン療法 / Mast cell / コクサッキーウイルス / Srcファミリーキナーゼ / Jagged / 関節リウマチ / 免疫寛容 / 口腔粘膜疾患 / アデノウイルス / CD8十T細胞 / CD4 / CTL / Immunity / 口腔扁平苔癬 / チロシンキナーゼ / アポトーシス / セリン・スレオニンキナーゼ / チロシンりん酸化 / 肥満細胞(MMC) / 酸化ストレス / マクロファージ / 消化管神経 / Oral lichen planus / 病理学 / Testosterone / goblet cell / 抗原認識 / 防御免疫 / IL-2レセプター / Discordant異種 / 免疫療法 / 肥満細胞 / Jak3欠損マウス / SOCS / 診断 / Cytotoxic T cells / 防御免役 / Th2 / Th1 / 抗原 / T細胞活性化 / チロシンキナ一ゼ / 薬剤誘導性免疫寛容系 / Syk / Co-stimulator / キナーゼ抑制因子 / 好酸球 / 樹状細胞 / 不死化 / CD45 / MAPキナーゼ / Expulsion / Diagnosis / Vaccination therapy / 脂質ラフト / Oral mucosal disease / 炎症 / CD4+ T cells / Protective immunity / 膠原病 Less

Development of a culture system to selectively induceγ δT-lymphocytes from embryonic and hematopoietic stem cellsPrincipal Investigator
- Principal Investigator
  
  KISHIHARA Kenji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Nagasaki International University
Establishment of the system to control T lymphocyte functions using Notch ligandsPrincipal Investigator
- Principal Investigator
  
  KISHIHARA Kenji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokushima
Notch分子によるヘルパーTリンパ球分化・活性化制御機構の解明
- Principal Investigator
  
  MAEKAWA Yoichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokushima
T lymphocyte-specific gene targeting of Notch receptor glycosyltransferase fringePrincipal Investigator
- Principal Investigator
  
  KISHIHARA Kenji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokushima
Jagged1を制御することによる癌免疫の増強に関する研究
- Principal Investigator
  
  安友康二
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokushima
Tリンパ球の生死を規定する分子機構の解明
- Principal Investigator
  
  安友康二
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokushima
サイトカインのシグナル制御機構とその破綻
- Principal Investigator
  
  吉村昭彦
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Kyushu University
Analysis of pathogenesis and establishment of novel diagnostic strategy of oral mucosal diseases by T cell receptorbased analysis
- Principal Investigator
  
  NAKAMURA Seiji
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kyushu University
Identification of oral squamous cell carcinoma-associated antigens recognized by T cells
- Principal Investigator
  
  NAKAMURA Seiji
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kyushu University
SELECTIVE GENE TRGETING OF TCR Vδ GENES AND ANALYSIS OF THE KNOCKOUT MICEPrincipal Investigator
- Principal Investigator
  
  KISHIHARA Kenji
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  KYUSHU UNIVERSITY
GENE TARGETING OF PROTEIN TYROSINE PHOSPHATASE PTP-JPrincipal Investigator
- Principal Investigator
  
  KISHIHARA Kenji
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  KYUSHU UNIVERSITY
Identification of oral squamous cell carcinoma-associated antigens recognized by T cells
- Principal Investigator
  
  NAKAMURA Seiji
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kyushu University
Elucidation of the immunological mechanism in tubulointerstitial damage. - investigation with knockout mouse
- Principal Investigator
  
  FUKUDA Kyoichi, 安藤高志
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  KYUSHU UNIVERSITY
THE ANALYSIS OF THE MECHANISM OF ALLOGRAFT REJECTION USING KNOCK OUT MICES
- Principal Investigator
  
  TOMITA Yukihiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  KYUSHU UNIVERSITY
T細胞活性化のシグナル伝達
- Principal Investigator
  
  斉藤隆
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
T細胞に発現される新しいチロシンホスファターゼの遺伝子と機能の解析Principal Investigator
- Principal Investigator
  
  岸原健二
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Immunology
- Research Institution
  Kyushu University
A study of defense mechanism against the infection of intestinal nematode by using knockout mice
- Principal Investigator
  
  TADA Isao
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  Kyusyu University
遺伝子ターゲティングマウスにおける免疫応答異常の解析Principal Investigator
- Principal Investigator
  
  岸原健二
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
T細胞活性化のシグナル伝達
- Principal Investigator
  
  斉藤隆
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
特異遺伝子欠損マウスにおける免疫応答異常の解析Principal Investigator
- Principal Investigator
  
  岸原健二
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
T細胞活性化のシグナル伝達
- Principal Investigator
  
  斉藤隆
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
The Role of CD45 in Leukocyte Differentiation and FunctionPrincipal Investigator
- Principal Investigator
  
  KISHIHARA Kenji
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  KYUSHU UNEVERSITY
SUBTRACTION PCR CLONING OF NOVEL LYMPHOCYTE-SPECIFIC PROTEIN TYROSINE PHOSPHATASE GENESPrincipal Investigator
- Principal Investigator
  
  KISHIHARA Kenji
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  KYUSHU UNIVERSITY

All 2010

All Journal Article

[Journal Article]2010
- Author(s)
  Alam MS、Maekawa Y、Kitamura A、Tanigaki K、Yoshimoto T、Kishihara K、Yasutomo K
- Journal Title
  
  Proceedings of national academy of sciences U.S.A. 107巻
  
  Pages: 5943-5948
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590491
[Journal Article] Essential role of IL-17A in the formation of a mycobacterial infection-induced granuloma in the lung2010
- Author(s)
  Okamoto Yoshida Y、Umemura M、Yahagi A、O'Brien RL、Ikuta K、Kishihara K、Hara H、Nakae S、Iwakura Y、Matsuzaki G
- Journal Title
  
  Journal of Immunology 184巻
  
  Pages: 4414-4422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590491

1. MATSUZAKI Goro (30229455)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. YOSHIDA Hiroki (40260715)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. TSUKUMO Shinichi (10346596)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. NAKAMURA Seiji (60189040)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. SHIRASUNA Kanemitsu (30093420)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 斉藤隆 (50205655)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. 南康博 (70229772)

# of Collaborated Projects: 3 results

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8. 高橋秀実 (40221361)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. 藤原大美 (70116094)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. 上出利光 (00160185)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. 安友康二 (30333511)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. MAEKAWA Yoichi (10294670)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. FUKUDA Kyoichi (90294925)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. FUJUKI Tsukasa (00420612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TADA Isao (60064531)

# of Collaborated Projects: 1 results

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16. KOGA Masataka (80136449)

# of Collaborated Projects: 1 results

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17. HIRAKATA Hideki (70181146)

# of Collaborated Projects: 1 results

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18. TOMITA Yukihiro (90180174)

# of Collaborated Projects: 1 results

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19. KURISU Kazuhiro (70294923)

# of Collaborated Projects: 1 results

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20. NISIMURA Yousuke (50301338)

# of Collaborated Projects: 1 results

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21. 原田守 (50260716)

# of Collaborated Projects: 1 results

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22. 吉村昭彦 (90182815)

# of Collaborated Projects: 1 results

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23. 箕口滋 (60322757)

# of Collaborated Projects: 1 results

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24. 安藤高志 (40281191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 滝本博明 (00253534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 嘉手納勉 (30325469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. MAK Tak w

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

kishihara kenji 岸原 健二

KISHIHARA Kenji 岸原 健二

Research Projects

Research Products

Co-Researchers

Development of a culture system to selectively induceγ δT-lymphocytes from embryonic and hematopoietic stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of the system to control T lymphocyte functions using Notch ligandsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

T lymphocyte-specific gene targeting of Notch receptor glycosyltransferase fringePrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Principal Investigator

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Principal Investigator

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Principal Investigator

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Research Institution

SELECTIVE GENE TRGETING OF TCR Vδ GENES AND ANALYSIS OF THE KNOCKOUT MICEPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

GENE TARGETING OF PROTEIN TYROSINE PHOSPHATASE PTP-JPrincipal Investigator

Principal Investigator

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Research Category

Research Field

Research Institution

Principal Investigator

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Principal Investigator

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Principal Investigator

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Principal Investigator

kishihara kenji 岸原健二

KISHIHARA Kenji 岸原健二