HARADA Mamoru 原田守

… Alternative Names

Researcher Number	50260716
Other IDs
External Links
Affiliation (Current)	2020: 島根大学, 学術研究院医学・看護学系, 教授
Affiliation (based on the past Project Information) *help	2018 – 2020: 島根大学, 学術研究院医学・看護学系, 教授 2006 – 2018: 島根大学, 医学部, 教授 2003 – 2005: Kurume University, Department of Immunology, Associate Professor, 医学部, 助教授 2000 – 2002: 久留米大学, 医学部, 講師 1994: 九州大学, 生体防御医学研究所, 助手
Review Section/Research Field	Principal Investigator General surgery / Biological Sciences / Tumor immunology / General surgery / Tumor therapeutics Except Principal Investigator Urology / Biological Sciences / Hematology / Basic Section 56030:Urology-related
Keywords	Principal Investigator 免疫療法 / 癌 / ペプチド / がん免疫 / 癌抗原 / CD4陽性T細胞 / 免疫学 / 抗原 / Toll様受容体 / 癌免疫療法 … More Except Principal Investigator 腎細胞癌 / ペプチドワクチン / 免疫療法 / 癌ワクチン / 腎細胞がん / 癌ワクチン療法 / EPOR / HIF-1 / PDL-1 / ペプチド / CD45 / p56^<1ck> / リンパ球 / ジーンターゲティング / 免疫異常 / Apaf1 / ミトコンドリア / アポトーシス / CA9 / VEGFR / ワクチン療法 / HLA-A24 / 樹状細胞 / テーラーメード / Dendritic cell / Taylor made / Peptide / がんワクチン / HLA-A2 / 複合免疫療法 / バイオマーカー Less

腎細胞癌に対するマルチペプチド癌ワクチンの開発、複合免疫療法としての有用性の検討Ongoing
- Principal Investigator
  
  植村天受
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kindai University
加齢に伴う免疫能の変化に立脚した化学療法との複合がん免疫療法の確立Principal InvestigatorOngoing
- Principal Investigator
  
  原田守
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Shimane University
Development of the HLA-A2 restricted multi-peptides vaccine for renal cell carcinoma.
- Principal Investigator
  
  UEMURA Hirotsugu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kindai University
Development of multi-peptide tumor vaccine for renal cell carcinoma
- Principal Investigator
  
  UEMURA Hirotsugu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kinki University
Effective anti-cancer immunotherapy by controling autophagyPrincipal Investigator
- Principal Investigator
  
  HARADA Mamoru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor immunology
- Research Institution
  Shimane University
Development of tailor made peptide vaccines for renal cell carcinoma
- Principal Investigator
  
  UEMURA Hirotsugu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kinki University
Anti-cancer immunotherapy targeting toll-like receptors expressed on cancer cells and killer T cellsPrincipal Investigator
- Principal Investigator
  
  HARADA Mamoru
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Shimane University
Study on anti-cancer immunotherapy targeting a tumor marker, SCCAPrincipal Investigator
- Principal Investigator
  
  HARADA Mamoru
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Shimane University
Clinical study of cancer immunotherapy with dendritic cells pulsed with Taylor made peptides
- Principal Investigator
  
  MUTA Hiromi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  KYUSHU UNIVERSITY
CD4陽性ヘルパーT細胞に認識される上皮性癌抗原遺伝子の同定Principal Investigator
- Principal Investigator
  
  原田守
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kurume University
Identification of epithelial cancer-associated antigens and application to cancer vaccinePrincipal Investigator
- Principal Investigator
  
  HARADA Mamoru
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kurume University
Apaf1欠損アポトーシス抵抗性細胞における癌化と細胞死の解析
- Principal Investigator
  
  吉田裕樹
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
特異遺伝子欠損マウスにおける免疫応答異常の解析
- Principal Investigator
  
  岸原健二
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University

All 2018 2017 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book

[Book] Effects of metronomic chemotherapy on immunity, in “Metronomic chemotherapy” (eds) Bocci G, Francia G.2014
- Author(s)
  Mamoru Harada
- Total Pages
  13
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-24501331
[Journal Article] Chloroquine augments TRAIL-induced apoptosis and induces G2/M phase arrest in human pancreatic cancer cells2018
- Author(s)
  Monma H, Iida Y, Moritani T, Okimoto T, Tanino R, Tajima Y, Harada M.
- Journal Title
  
  PLOS ONE
  
  Volume: 7
- DOI
  10.1371/journal.pone.0193990
- NAID
  120006539383
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07217
[Journal Article] Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer.2018
- Author(s)
  Tanino R, Tsubata Y, Harashima N, Harada M, Isobe T.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Pages: 16807-16821
- DOI
  10.18632/oncotarget.24704
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07217
[Journal Article] Bcl-2 inhibition sensitizes triple-negative human breast cancer cells to doxorubicin.2018
- Author(s)
  Inao T, Iida Y, Moritani T, Okimoto T, Tanino R, Kotani H, Harada M.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Pages: 25545-25556
- DOI
  10.18632/oncotarget.25370
- NAID
  120006539384
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07217, KAKENHI-PROJECT-16K15135
[Journal Article] Contrasting effects of cyclophosphamide on anti-CTLA-4 blockade therapy in two tumor mouse models.2017
- Author(s)
  Iida Y, Harashima N, Motoshima T, Komohara Y, Eto M, Harada M.
- Journal Title
  
  Cancer Science,
  
  Volume: 108 Pages: 1974-1984
- DOI
  10.1111/cas.13337
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07217
[Journal Article] HIF-2α dictates the susceptibility of pancreatic cancer cells to TRAIL by regulating survivin expression2017
- Author(s)
  Harashima Nanae、Takenaga Keizo、Akimoto Miho、Harada Mamoru
- Journal Title
  
  Oncotarget,
  
  Volume: 8 Pages: 42887-42900
- DOI
  10.18632/oncotarget.17157
- NAID
  120006532063
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10594, KAKENHI-PROJECT-17K07217, KAKENHI-PROJECT-16K21177
[Journal Article] Hypoxia-inducing factor (HIF)-1a;-derived peptide capable of inducing cancer-reactive cytotoxic T lymphocytes from HLA-A24+ patients with renal cell carcinoma.2017
- Author(s)
  1.Minami T, Matsumura N, Sugimoto K, Shimizu N, De Velasco M, Nozawa M, Yoshimura K, Harashima N, Harada M, Uemura H.
- Journal Title
  
  International Immunopharmacology
  
  Volume: 44 Pages: 197-202
- DOI
  10.1016/j.intimp.2017.01.014
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05466, KAKENHI-PROJECT-17K07217
[Journal Article] Identification of Programmed Death Ligand 1-derived Peptides Capable of Inducing Cancer-reactive Cytotoxic T Lymphocytes From HLA-A24+ Patients With Renal Cell Carcinoma.2015
- Author(s)
  Minami T., Minami T., Shimizu N., Yamamoto Y., De Velasco MA., Nozawa M., Yoshimura K., Harashima N., Harada M., Uemura H.
- Journal Title
  
  J Immunother.
  
  Volume: 38 (7) Pages: 285-289
- DOI
  10.1097/cji.0000000000000090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430150, KAKENHI-PROJECT-25293336
[Journal Article] Prognostic impact of programmed cell death 1 expression in human leukocyte antigen class I-positive hepatocellular carcinoma after curative hepatectomu2015
- Author(s)
  Umemoto Y, Okano S, Matsumoto Y, Nakagawara H, Matono R, Yoshiya S, Yamashita YI, Yoshizumi T, Ikegami T, Soejima Y, Harada M, Aishima S, Oda Y, Shirabe K, Maehara Y.
- Journal Title
  
  Journal of Gastroenterolog
  
  Volume: not determined Pages: 65-67
- DOI
  10.1007/s00535-014-0933-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390320, KAKENHI-PROJECT-24501331, KAKENHI-PROJECT-26670583, KAKENHI-PROJECT-15K10167
[Journal Article] Intermittent chemotherapy can retain the therapeutic potential of anti-CD137 antibody during the late tumor-bearing state2015
- Author(s)
  Tongu M, Harashima N, Tamada K, Chen L, Harada M
- Journal Title
  
  Cancer Sci.
  
  Volume: 106 Pages: 9-17
- DOI
  10.1111/cas.12568
- NAID
  120005982740
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24501331, KAKENHI-PROJECT-25290057, KAKENHI-PROJECT-25430150
[Journal Article] New polycomb group protein enhancer of zeste homolog (EZH) 2-derived peptide with the potential to induce cancer-reactive cytotoxic T lymphocytes in prostate cancer patients with HLA-A3 supertype alleles.2015
- Author(s)
  Minami T, Minami T, Shimizu N, Yamamoto Y, De Velasco M A, Nozawa M, Yoshimura K, Harashima N, Harada M, Uemura H.
- Journal Title
  
  Int Immunopharmacol.
  
  Volume: 26 Pages: 133-138
- DOI
  10.1016/j.intimp.2015.03.023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24501331, KAKENHI-PROJECT-24592416, KAKENHI-PROJECT-25430150, KAKENHI-PROJECT-25293336
[Journal Article] Transfection of poly(I:C) can induce reactive oxygen species-triggered apoptosis and interferon--mediated growth arrest in human renal cell carcinoma cells via innate adjuvant receptors and the 2-5A system2014
- Author(s)
  Harashima N, Minami T, Uemura H, Harada M
- Journal Title
  
  Mol Cancer.
  
  Volume: 13 Pages: 217-217
- DOI
  10.1186/1476-4598-13-217
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24501331, KAKENHI-PROJECT-25293336, KAKENHI-PROJECT-25430150
[Journal Article] Bcl-2 family inhibition sensitizes human prostate cancer cells to docetaxel and promotes unexpected apoptosis under caspase-9 inhibition2014
- Author(s)
  amaki H, Harashima N, Hiraki M, Arichi N, Nishimura N, Shiina H, Naora K, Harada M
- Journal Title
  
  Oncotarget
  
  Volume: 5 Pages: 11399-11412
- NAID
  120005982736
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24501331
[Journal Article] Identification of erythropoietin receptor-derived peptides having the potential to induce cancer-reactive cytotoxic T lymphocytes from HLA-A24+ patients with renal cell carcinoma.2014
- Author(s)
  Minami T, Minami T, Shimizu N, Yamamoto Y, De Velasco M, Nozawa M, Yoshimura K, Harashima N, Harada M, Uemura H
- Journal Title
  
  Int Immunopharmacol.
  
  Volume: 20 Pages: 59-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293336
[Journal Article] Identification of erythropoietin receptor-derived peptides having the potential to induce cancer-reactive cytotoxic T lymphocytes from HLA-A24+ patients with renal cell carcinoma2014
- Author(s)
  Minami T, Minami T, Shimizu N, Yamamoto Y, De Velasco M, Nozawa M, Yoshimura K, Harashima N, Harada M, Uemura H.
- Journal Title
  
  International Immunopharmacology
  
  Volume: 20 Pages: 59-65
- DOI
  10.1016/j.intimp.2014.02.018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24501331, KAKENHI-PROJECT-25430150
[Journal Article] Identification of erythropoietin receptor-derived peptides having the potential to induce cancer-reactive cytotoxic T lymphocytes from HLA-A24(+) patients with renal cell carcinoma.2014
- Author(s)
  Minami T, Minami T, Shimizu N, Yamamoto Y, De Velasco M, Nozawa M, Yoshimura K, Harashima N, Harada M, Uemura H.
- Journal Title
  
  Int Immunopharmacol.
  
  Volume: 20 Pages: 59-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293336
[Journal Article] Metronomic chemotherapy with low-dose cyclophophamide plus gemcitabine can induce anti-tumor T cell immunity in vivo2013
- Author(s)
  Miki Tongu, Nanae Harashima, Hiroyuki Monma, Touko Inao, Takaya Yamada, Hideyuki Kawauchi, Mamoru Harada
- Journal Title
  
  Cancer Immunology Immunotherapy
  
  Volume: 62 Pages: 383-391
- DOI
  10.1007/s00262-012-1343-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659796, KAKENHI-PROJECT-23701074, KAKENHI-PROJECT-24501331
[Journal Article] Pifithrin-mu, an inhibitor of heat-shock protein 70, can increase the antitumor effects of hyperthermia against human prostate cancer cells2013
- Author(s)
  Sekihara M, Harashima N, Tongu M, Tamaki Y, Uchida N, Inomata T, Harada M.
- Journal Title
  
  PLoS One
  
  Volume: 8
- DOI
  10.1371/journal.pone.0078772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501331, KAKENHI-PROJECT-25430150
[Journal Article] The HSP70 and autophagy inhibitor pifithrin-μ enhances the antitumor effects of TRAIL on human pancreatic cancer.2013
- Author(s)
  Monma H, Harashima N, Inao T, Okano S, Tajima Y, and Harada M
- Journal Title
  
  Mol Cancer Ther.
  
  Volume: 12(4) Pages: 341-351
- DOI
  10.1158/1535-7163.mct-12-0954
- NAID
  120005982741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701074, KAKENHI-PROJECT-24501331, KAKENHI-PROJECT-25430150, KAKENHI-PROJECT-25462112
[Journal Article] Interleukin-17A is involved in enhan-cement of tumor progression in murine intestine2012
- Author(s)
  K.Oshiro
- Journal Title
  
  Immunobiology
  
  Volume: 217 Pages: 54-60
- DOI
  10.1016/j.imbio.2011.08.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009, KAKENHI-PROJECT-21390132, KAKENHI-PROJECT-21591668, KAKENHI-PROJECT-24501331, KAKENHI-PROJECT-21390303
[Journal Article] Oral ingestion of Lentinula edodes mycelia extract can restore the antitumor T cell response of mice inoculated with colon-26 cells into the subserosal space of the cecum.2012
- Author(s)
  Harada M, et al.(5人中5番目)
- Journal Title
  
  Oncology Reports
  
  Volume: 27 Pages: 325-332
- DOI
  10.3892/or.2011.1549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591668, KAKENHI-PROJECT-24501331
[Journal Article] Antitumor effects of cytoplasmic delivery of an innate adjuvant receptor ligand, poly(I:C), on human breast cancer.2012
- Author(s)
  Harada M., et al.(8人中8番目)
- Journal Title
  
  Breast Cancer Res Treat.
  
  Volume: (in press) Pages: 89-100
- DOI
  10.1007/s10549-011-1930-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591668, KAKENHI-PROJECT-22501023, KAKENHI-PROJECT-23701074, KAKENHI-PROJECT-24501331
[Journal Article] Combining a peptide vaccine with oral ingestion of Lentinula edodes mycelia extract enhances anti-tumor activity in B16 melanoma-bearing mice2012
- Author(s)
  Harada M., et al.(7人中7番目)
- Journal Title
  
  Cancer Immunology Immunotherapy
  
  Volume: (in press)
- URL
  http://www.springerlink.content/0340-7004.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591668
[Journal Article] Provision of continuous maturation signaling to dendritic cells by RIG-1-stimulating cytosolic RNA synthesis of Sendai virus.2012
- Author(s)
  Okano S,, et al
- Journal Title
  
  J. Immunol.
  
  Volume: 186 Pages: 1828-1839
- DOI
  10.4049/jimmunol.0901641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249072, KAKENHI-PROJECT-21390364, KAKENHI-PROJECT-21591668, KAKENHI-PROJECT-22659246, KAKENHI-PLANNED-22133009
[Journal Article] Role of the PI3K/Akt pathway and autophagy in TLR3 signaling-induced apoptosis and growth arrest of humna prostate cancer cells.2012
- Author(s)
  Harashima N, Inao T, Imamura R, Okano S, Suda T, Harada M.
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: 61 Pages: 667-676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501331
[Journal Article] Combining a peptide vaccine with oral ingestion of lentinula edodes mycelia extract enhances anti-tumor activity in B16 melanoma-bearing mice.2012
- Author(s)
  Tanaka K, Harashima N, et al.
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: 61 Pages: 2143-2152
- DOI
  10.1007/s00262-012-1275-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701074, KAKENHI-PROJECT-24501331
[Journal Article] Fas ligand has greater impacts on apoptosis and inflammation in ischemic acute kidney injury than TNF-α2012
- Author(s)
  Harashima, N., Inao, T., Imamura, R., et. al.
- Journal Title
  
  Cancer Immunol Immunother
  
  Volume: (in press) Pages: 27-38
- DOI
  10.1007/s00262-011-1132-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590329, KAKENHI-PROJECT-21591668, KAKENHI-PROJECT-22501023, KAKENHI-PUBLICLY-23114505, KAKENHI-PROJECT-23390092, KAKENHI-PROJECT-23701074, KAKENHI-PROJECT-24590374
[Journal Article] Oral ingestion of Lentinus edodes mycelia extract inhibits B16 melanoma growth via mitigation of regulatory T cell-mediated immunosuppression2011
- Author(s)
  Harada M, et al.(6人中6番目)
- Journal Title
  
  Cancer Science
  
  Volume: 102 Pages: 516-521
- DOI
  10.1111/j.1349-7006.2010.01841.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591668
[Journal Article] Immunogenic chemotherapy with cyclophophamide and doxorubicin against established murine carcinoma2010
- Author(s)
  Harada M, et al.(5人中5番目)
- Journal Title
  
  Cancer Immunology Immunotherapy
  
  Volume: 59 Pages: 769-777
- DOI
  10.1007/s00262-009-0797-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591668
[Journal Article] 'Sterile' inflammation and autophagy in cancer immunotherapy2010
- Author(s)
  Harada M, Harashima N
- Journal Title
  
  Immunotherapy
  
  Volume: 2 Pages: 599-601
- DOI
  10.2217/imt.10.55
- Data Source
  KAKENHI-PROJECT-21591668
[Journal Article] 'Sterile' inflammation and autophagy in cancer immunotherapy2010
- Author(s)
  Harada M
- Journal Title
  
  Immunotheray
  
  Volume: Vol.2 Pages: 599-601
- Data Source
  KAKENHI-PROJECT-21591668
[Journal Article] Allogeneic cell therapy from immunized donors with tumor antigen peptide enhances the anitumor effect after cyclophosphamide-using nonmyeloablative allogenenic hematopoietic cell transplantation in mice.2009
- Author(s)
  Hamaguchi M, Harada M, et al..(10人中8番目)
- Journal Title
  
  Cancer Science 100
  
  Pages: 138-143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] Delayed growth of EL4 lymphoma in SR-A-deficient mice is due to up-regulation of nitric oxide and IFN-production by tumor-associated macrophages2009
- Author(s)
  Harada M, et al.(8人中8番目)
- Journal Title
  
  Cancer Science
  
  Volume: 100 Pages: 2160-2166
- DOI
  10.1111/j.1349-7006.2009.01296.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591668
[Journal Article] Roles of proinflammatory cytokines and the Fas/FasL interaction in pathogenesis of inflammatory myopathies2009
- Author(s)
  Harada M., et al.(8人中8番目)
- Journal Title
  
  Immunology
  
  Volume: 128 Pages: 589-599
- DOI
  10.1111/j.1365-2567.2008.03039.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591668
[Journal Article] Allogeneic cell therapy from immunized donors with tumor antigen peptide enhances the anitumor effect after cyclophosphamide-using nonmyeloablative allogenenic hematopoietic cell transplantation in mice2009
- Author(s)
  Hamaguchi M, Eto M 他8名
- Journal Title
  
  Cancer Science
  
  Volume: 100巻 Pages: 138-143
- DOI
  10.1111/j.1349-7006.2008.01014.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390295, KAKENHI-PROJECT-21591668
[Journal Article] Roles of proinflammatory cytokines and theFas/FasL interaction in pathogenesis ofInflammatory myopathies.2009
- Author(s)
  Kondo M, Harada M. et al.(6人中6番目)
- Journal Title
  
  Immunology in press
  
  Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] A correlation between symptom severity and unbalanced reactive IgA production in Japanese ceder pollinosis patients.2008
- Author(s)
  Komatsu N, Harada M,et al.(8人中2番目)
- Journal Title
  
  Asian Pacific Journal of Allergy and Immunology 26
  
  Pages: 97-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] Identification of Eph6 variant-derived epitope peptides recognized by cytotoxic T-lymphocytes from HLA-A24+ malignant glioma patients2008
- Author(s)
  Jin M, Harada M,et al.(9人中4番目)
- Journal Title
  
  Oncology Reports 19
  
  Pages: 1277-1283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] Posttransplant administration of cyclophosphamide and donor lymphocyte infusion induces potent antitumor immunity to solid tumor.2008
- Author(s)
  Eto M, Harada M,et al.(12人中6番目)
- Journal Title
  
  Clinical Cancer Research 14
  
  Pages: 2833-2840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] Kinesin superfamily protein-derived peptides with the ability to induce glioma-reactive cytotoxic T lymphocytes in HLA-A24^+ glioma patients.2007
- Author(s)
  Harada M, et al.(4人中1番目)
- Journal Title
  
  Oncology Reports 17
  
  Pages: 629-636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] HLA-G as a target molecule in specific immunotherapy against renal cell carcinoma2007
- Author(s)
  Komohara Y, Harada M,et al.(8人中2番目)
- Journal Title
  
  Oncology Reports 18
  
  Pages: 1463-1468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] Identification of SART3-derived peptides having the potential to induce cancer-reactive cytotoxic T lymphocytes from prostate cancer patients with HLA-A3 supertype alleles2007
- Author(s)
  Minami T, Harada M. et al.(8人中8番目)
- Journal Title
  
  Cancer Immunology Immunotherapy 56
  
  Pages: 689-698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] Identification of Lck-derived peptides applicable to anti-cancer vaccine for patients with human leukocyte antigen-A3 supertype alleles2007
- Author(s)
  Naito M, Harada M. et al.(9人中9番目)
- Journal Title
  
  British Journal of Cancer 97
  
  Pages: 1648-1654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] Kinesin superfamily protein-derived peptides with the ability to induce glioma-reactive cytotoxic T lymphocytes in HLA-A24+ glioma patients2007
- Author(s)
  Harada, M.
- Journal Title
  
  Oncology Reports 17
  
  Pages: 629-636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] Differential levels of human leukocyte antigen-class I, multidrug-resistance 1 and androgen receptor expressions in untreated prostate cancer cells: The robustness of prostate cancer.2007
- Author(s)
  Homma S, Harada M,et al.(7人中3番目)
- Journal Title
  
  Oncology Reports 18
  
  Pages: 343-346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] Cyclophosphamide-using nonmyeloablative allogeneic cell therapy against renal cancer with a reduced risk of graft-versus-host disease.2007
- Author(s)
  Eto M, Harada M, et al.(10人中4番目)
- Journal Title
  
  Clinical Cancer Research 13
  
  Pages: 1029-1035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] Immunological evaluation of neoadjuvant peptide vaccination before radical prostatectomy for patients with localized prostate cancer.2007
- Author(s)
  Noguchi M, Harada M, et al.(6人中3番目)
- Journal Title
  
  Prostate 67
  
  Pages: 933-942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] peptides of the polycomb group protein enhancer of zeste homolog 2 (EZH2) with the potential to induce cancer-reactive cytotoxic T lymphocytes in HLA-A2^+ prostate cancer patients.2007
- Author(s)
  Itoh Y, Harada M. et al.(8人中8番目)
- Journal Title
  
  Oncology Reports 18
  
  Pages: 1231-1237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] New peptide vaccine candidates for epithelial cancer patients with HLA-A3 supertype allelels.2007
- Author(s)
  Matsueda S, Harada M. et al.(8人中8番目)
- Journal Title
  
  Journal of Immunotherapy 30
  
  Pages: 274-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] Identification of target antigens in specific immunotherapy for renal cell carcinoma2007
- Author(s)
  Komohara Y, Harada M, et al.(8人中2番目)
- Journal Title
  
  Journal of Urology 177
  
  Pages: 1157-1162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] Combination therapy of personalized peptide vaccination and low-dose estramustine phosphate for metastatic hormone refractory prostate cancer patients: An analysis of prognostic factors in the treatment2007
- Author(s)
  Noguchi M, Harada M,et al.(10人中7番目)
- Journal Title
  
  Oncology Research 16
  
  Pages: 341-349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] Immunological evaluation of personalized peptide vaccination in combination with a 5-fluorouracil derivative (TS-1) for advanced gastric or colorectal carcinoma patients.2007
- Author(s)
  Sato Y, Harada M, et al.(14人中13番目)
- Journal Title
  
  Cancer Science 98
  
  Pages: 1113-1119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] Anti-cancer vaccine candidates in specific immunotherapy for bladder carcinoma2006
- Author(s)
  Komohara Y, Harada M, et al.(2人中8番目)
- Journal Title
  
  International Journal of Oncology 29
  
  Pages: 1555-60
- NAID
  120005587481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] Anti-tumor effect of systemic and local immunization with a cytotoxic T lymphocyte-directed peptide in combination with a local injection of OK-4322006
- Author(s)
  Ono T, Harada M, et al.(10人中2番目)
- Journal Title
  
  Clinical Cancer Research 12
  
  Pages: 1325-1332
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] In vivo growth of transitional and renal carcinoma cell lines can be suppressed by adenovirus-mediated expression of a solubleform of vascular endothelial growth factor receptor2006
- Author(s)
  Ichikura H, Harada M,et al.(8人中4番目)
- Journal Title
  
  Oncology Reports 15
  
  Pages: 1333-1337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] Identification of Hepatitis C virus (HCV) 2a-derived epitope peptides having the capacity to induce cytotoxic T lymphocytes in human leukocyte antigen-A24^+ and HCV2a-infected patients2006
- Author(s)
  Wang Y, Harada M, et al.(3人中8番目)
- Journal Title
  
  Cellular Immunology 241
  
  Pages: 38-46
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] new epitope peptides derived from Hepatitis C virus (HCV) 2a which have the capacity to induce cytotoxic T lymphocytes in HLA- A2^+ HCV-infected patients2006
- Author(s)
  Wang Y, Harada M, et al.(8人中3番目)
- Journal Title
  
  Microbiol. Immunol 50
  
  Pages: 857-865
- NAID
  10018398215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] Identification of squamous cell carcinoma antigen-derived peptides having the capacity of inducing cancer-reactive CTLs in HLA-A24^+ cancer patients2006
- Author(s)
  Homma, Harada M,et al.(2人中12番目)
- Journal Title
  
  International Journal of Oncology 29
  
  Pages: 577-587
- NAID
  120005587483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Journal Article] Prostate-specific antigen-reactive cytotoxic T lymphocyte precursors in colon cancer patients2006
- Author(s)
  Wang Y, Harada M,et al.(7人中2番目)
- Journal Title
  
  Oncology Reports 15
  
  Pages: 317-321
- NAID
  120005587482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591449
[Presentation] p53遺伝子変異を有するトリプルネガティブ乳癌細胞株に対するdoxorubicinとBcl-2 阻害剤（ABT-199）の併用効果2018
- Author(s)
  稲尾瞳子、原田守
- Organizer
  第118回日本外科学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07217
[Presentation] 抗がん剤pemetrexedでsenescence に陥ったヒト肺がん細胞は細胞傷害性T細胞に傷害されやすい2018
- Author(s)
  原田守、沖本民生、谷野良輔、飯田雄一、礒部威
- Organizer
  第22回がん免疫学会
- Data Source
  KAKENHI-PROJECT-17K07217
[Presentation] Local delivery of CCL19-expressing mesenchymal stromal cells suppresses the tumor growth via promoting infiltration of immune cells.2018
- Author(s)
  Iida Y, Yoshikawa R, Murata A, Matsuzaki Y, Harada M
- Organizer
  第47回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-17K07217
[Presentation] Doxorubicinはヒト乳がん細胞にsenescenceを誘導し細胞傷害性免疫細胞に対する感受性を増強させる2018
- Author(s)
  稲尾瞳子、原田守
- Organizer
  第26回日本乳がん学会
- Data Source
  KAKENHI-PROJECT-17K07217
[Presentation] Anti-cancer drugs induce senescence in cancer cells and increase their sensitivity to CAR-T cells2018
- Author(s)
  Harada M, Okimoto T, Inao T, Tanino R, iida Y, Isobe T.
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07217
[Presentation] 間葉系幹細胞の腫瘍局所残存性を利用した新規抗がん免疫療法のマウスモデルの確立2018
- Author(s)
  飯田雄一、吉川倫太郎、松崎有未、原田守
- Organizer
  第22回がん免疫学会
- Data Source
  KAKENHI-PROJECT-17K07217
[Presentation] Chemotherapy-induced senescent cancer cells are good targets for T cell-based anti-cancer immunotherapy2018
- Author(s)
  Harada M, Kotani H, Iida Y.
- Organizer
  第47回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-17K07217
[Presentation] Doxorubicin induces cellular senescence in human breast cancer cells and sensitizes them to cytotoxic T-lymphocytes.2018
- Author(s)
  Inao T, Iida Y, Kotani H, Harada M.
- Organizer
  San Antonio Breast Cancer Symposium.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07217
[Presentation] Pros and cons of cyclophosphamide in anti-CTLA-4 antibody-treated different tumor mouse models2017
- Author(s)
  飯田雄一、原嶋奈々江、元島崇信、菰原義弘、江藤正俊、原田守
- Organizer
  第21回日本がん免疫学会
- Data Source
  KAKENHI-PROJECT-17K07217
[Presentation] トリプルネガティブ乳癌細胞株に対するdoxorubicinとBcl-2 阻害剤の併用効果2017
- Author(s)
  稲尾瞳子、原嶋奈々江、原田守
- Organizer
  第25回日本乳癌学
- Data Source
  KAKENHI-PROJECT-17K07217
[Presentation] Pemetrexed-resistant non-small cell lung cancer cell lines have novel drug-resistance mechanisms.2017
- Author(s)
  Tanino R, Tsubata Y, Harashima N, Harada M, Isobe T.
- Organizer
  世界肺癌学会(WCLC2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07217
[Presentation] Contrasting interaction between cyclophosphamide and anti-CTLA-4 therapy in different mouse tumor models.2017
- Author(s)
  原田守、飯田雄一、原嶋奈々江、元島崇信、菰原義弘、江藤正俊
- Organizer
  第76回日本癌学会
- Data Source
  KAKENHI-PROJECT-17K07217
[Presentation] 低用量 chemotherapyと抗CD137抗体の併用により誘導される持続的な抗腫瘍免疫応答2013
- Author(s)
  頓宮美樹、原嶋奈々江、山田高也、岡野慎士、玉田耕治、原田守
- Organizer
  第17回日本がん免疫学会
- Place of Presentation
  全日空ホテル（宇部）
- Data Source
  KAKENHI-PROJECT-24501331
[Presentation] Mechanisms of an HSP70 inhibitor pifithrin-mu to enhance TRAIL-induced apoptosis of pancreatic cancer cells2013
- Author(s)
  Monma H, Harashima N, Hari Y, Tajima Y, Harada M
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-24501331
[Presentation] A novel HSP70 inhibitor pifithrin-mu enhances the antitumor effect of radiation on human prostate cancer.2013
- Author(s)
  Sekihara K, Harashima N, Tamaki Y, Hieda Y, Uchida N, Inomata T, Harada M
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-24501331
[Presentation] CD4 T cell-mediated masking effects of the immunogenicity of tumor-associated antigens are qualitatively and quantitatively different depending on the individual antigens2013
- Author(s)
  Okano S, Yamashita Y, Harashima N, Ikegami T, Yoshizumi T, Shirabe K, Harada M, Yoshikai Y, and Maehara Y
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-24501331
[Presentation] Restoration of the TRAIL susceptibility of human pancreatic cancer cells by inhibition2013
- Author(s)
  Harashima N, Hari Y, Monma H, Tajima Y, Harada M
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-24501331
[Presentation] Long-lasting suppression of CT26 growth after low-dose chemotherapy with cyclophosphamide plus gemcitabine followed by anti-CD137 antibody.2013
- Author(s)
  Harada M, Okano S, Tanada K, Harashima N
- Organizer
  第42回日本免疫学会学術総会
- Place of Presentation
  幕張メッセ（千葉）
- Data Source
  KAKENHI-PROJECT-24501331
[Presentation] HSP70阻害剤pifithrin-muがPanc-1膵癌細胞に対するTRAIL誘導性アポトーシスを増強する機序2013
- Author(s)
  門馬浩行、原嶋奈々江、波里瑶子、田島義証、原田守
- Organizer
  第17回日本がん免疫学会
- Place of Presentation
  全日空ホテル（宇部）
- Data Source
  KAKENHI-PROJECT-24501331
[Presentation] Poly(I:C)トランスフェクションによるROS産生を伴った癌細胞死誘導とインターフェロン制御分子の関与2013
- Author(s)
  原嶋奈々江、岡野慎士、原田守
- Organizer
  第17回日本がん免疫学会
- Place of Presentation
  全日空ホテル（宇部）
- Data Source
  KAKENHI-PROJECT-24501331
[Presentation] Poly(I : C)トランスフェクションによるヒト乳癌細胞に対する抗がん効果とオートファジー2011
- Author(s)
  原田守
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋コングレスセンター(名古屋)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] Lentinula edodes mycelia抽出物の予防的経口摂取はTreg抑制を介してワクチンによる抗癌効果を増強する2011
- Author(s)
  原田守
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋コングレスセンター(名古屋)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] Lentinula edodes mycelia抽出物の経口摂取はTreg抑制により抗癌ペプチドワクチン効果を増強・持続させる2011
- Author(s)
  原田守
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋コングレスセンター(名古屋)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] Neoadjuvant immunotherapy using IL12/DC for control of recurrent hepatocellular carcinoma in immunosuppressed mice2011
- Author(s)
  原田守
- Organizer
  第15回日がん免疫学会総会
- Place of Presentation
  千里ライフサイエンスセンター(大阪)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] 移植後肝細胞癌再発抑制におけるIL-12と樹状細胞を用いた術前補助免疫療法の抗腫瘍効果の検討2011
- Author(s)
  原田守
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋コングレスセンター(名古屋)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] Apoptosis and ROS production in ploy(I : C)-transfected human renal cell carcinoma2011
- Author(s)
  Harada Mamoru
- Organizer
  第40回日本免疫学会総会
- Place of Presentation
  幕張メッセ(千葉)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] TregとMDSCをターゲットとしたシクロホスファマイドとゲムシタビンの間欠投与による化学療法2011
- Author(s)
  原田守
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋コングレスセンター(名古屋)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] Neoadjuvant immunotherapy using IL12/DC for control of recurrent hepatocellular carcinoma in immunosppressed mice2011
- Author(s)
  Harada Mamoru
- Organizer
  第70回日本癌学会総会,第40回日本免疫学会総会
- Place of Presentation
  幕張メッセ(千葉)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] 乳癌細胞に発現するアジュバント受容体を利用したimmunogenic cancer cell deathの誘導2011
- Author(s)
  原田守
- Organizer
  第15回日がん免疫学会総会
- Place of Presentation
  千里ライフサイエンスセンター(大阪)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] Role of autophagy in apoptosis of human cancer cells after stimulation throush innate adjuvant receptor2011
- Author(s)
  Harada M
- Organizer
  第40回日本免疫学会総会
- Place of Presentation
  千葉(幕張メッセ)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] Role of autophagy in apoptosis of human cancer cells after stimulation through innate adjuvant receptor2011
- Author(s)
  Harada Mamoru
- Organizer
  第40回日本免疫学会総会
- Place of Presentation
  幕張メッセ(千葉)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] シイタケ菌糸体抽出物によるTreg免疫抑制の解除を介した腫瘍特異的CTLの誘導2010
- Author(s)
  原田守
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪国際会議場(大阪)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] Poly(I : C)のトランスフェクションによるヒト乳癌細胞でのアポトーシスとオートファジーの誘導2010
- Author(s)
  原田守
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪国際会議場(大阪)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] TLR3シグナルはPI3K/Akt経路の不活化を介してヒト前立腺癌細胞に細胞死と増殖抑制を誘導する2010
- Author(s)
  原田守
- Organizer
  第14回日本がん免疫学会総会
- Place of Presentation
  ホテル熊本(熊本)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] RIG-1-stimulating cytosolic RNA synthesis of Sendai virus(rSeV) is a novel stimulant for human dendritic cells2010
- Author(s)
  原田守
- Organizer
  第14回日本がん免疫学会総会
- Place of Presentation
  ホテル熊本(熊本)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] TLR3 ligand-induced apoptotic cell death with autophagy and growth arrest in human prostate cancer cells2010
- Author(s)
  Harada Mamoru
- Organizer
  国際免疫学会
- Place of Presentation
  神戸国際会議場(神戸)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] リコンビナントセンダイウイルスによるRIG-1刺激性細胞内RNA合成はヒト樹状細胞の新規刺激剤である2010
- Author(s)
  原田守
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪国際会議場(大阪)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] Induction of apoptosis and growth arrest of human breast cancer cells by targeting a cytoplasmic RIG-I-like receptor2010
- Author(s)
  Harada Mamoru
- Organizer
  The 20^<th> HCS-The three Universities' Consortium International Symposium
- Place of Presentation
  広島国際会議場
- Year and Date
  2010-10-31
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] Provision of continuous maturation signaling to dendritic cells(DC) by RIG-1-stimulating cytosolic RNA synthesis of recombinant Sendai virus(rSeV)2010
- Author(s)
  Harada Mamoru
- Organizer
  国際免疫学会
- Place of Presentation
  神戸国際会議場(神戸)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] TLR3 ligand-induced apoptosis of prostate cancer cells2009
- Author(s)
  Harada M
- Organizer
  第39回日本免疫学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] Immunogenic chemotherapy with cyclophosphamide and adriamycin against established murine colon carcinoma2009
- Author(s)
  原田守
- Organizer
  第13回日本がん免疫学会総会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] TLR3 ligand-induced apoptosis of prostate cancer cells2009
- Author(s)
  Mamoru Harada
- Organizer
  第39回日本免疫学会総会
- Place of Presentation
  大阪国際会議場(大阪)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] Immunogenic chemotherapy with cyclophosphamide and adriamycin against established murine colon carcinoma2009
- Author(s)
  原田守
- Organizer
  第13回日本がん免疫学会総会
- Place of Presentation
  北九州国際会議場(北九州)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] TLR3 ligand-induced prostate cancer cell death through endogenous production of type I IFN2009
- Author(s)
  Harada Mamoru
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  パシフィコ横浜(横浜)
- Data Source
  KAKENHI-PROJECT-21591668
[Presentation] 同種造血幹細胞移植後の腎細胞癌患者由来T細胞が認識する新規腫瘍抗原の同定とその発現2008
- Author(s)
  原田守
- Organizer
  第12回基盤的癌免疫研究会総会
- Place of Presentation
  埼玉
- Data Source
  KAKENHI-PROJECT-18591449
[Presentation] Roles of pro- inflammatory cytokines and Fas in the pathogenesis of inflammatory myopathies2008
- Author(s)
  HARADA Mamoru
- Organizer
  第38回日本免疫学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18591449
[Presentation] Cyclophosphamideとadriacycinによる抗がん免疫応答の増強2008
- Author(s)
  原田守
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18591449
[Presentation] Vaccination of donors with tumor antigen peptides enhances antitumor effects in nonmyeloablative allogenenic cell therapy2007
- Author(s)
  HARADA Mamoru
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18591449
[Presentation] Evidence of the extrathymic development of tyrosinase-related protein(TRP)2-recognizing CD8+T cells with Iow avidity2007
- Author(s)
  Harada, M.
- Organizer
  第37回日本免疫学会
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-18591449
[Presentation] TRP2 を認識するlow avidity CD8+ T細胞の胸腺外分化/Evidence of the extrathymic development of tyrosinae-related protein (TRP)2-recognizing CD8+ T cells with low avidity2007
- Author(s)
  HARADA Mamoru
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18591449
[Presentation] Kinesin superfamily protein-derived peptides with the ability to induce glioma-reactive CTLs in HLA-A24+ glioma patients2006
- Author(s)
  HARADA mamoru
- Organizer
  第36回日本免疫学会総会・学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18591449
[Presentation] Identification of SART3- derived peptides having the potential to induce cancer-reactive CTLs from prostate cancer patients with HLA-A3 supertype alleles2006
- Author(s)
  HARADA Mamoru
- Organizer
  第36回日本免疫学会総会・学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18591449
[Presentation] 腎癌・膀胱癌に対するワクチン療法に有用な抗原ペプチドの検討2006
- Author(s)
  原田守
- Organizer
  第65回日本癌学会学術集総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18591449
[Presentation] 未治療前立腺癌組織でのHLAクラスI,MRP1とアンドロゲンレセプター発現の検討2006
- Author(s)
  原田守
- Organizer
  第65回日本癌学会学術集総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18591449
[Presentation] 前立腺癌患者再燃早期におけるテーラーメイドペプチドワクチン療法の可能性2006
- Author(s)
  原田守
- Organizer
  第65回日本癌学会学術集総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18591449
[Presentation] HIF-2の阻害はヒト膵がん細胞のTRAIL感受性を増強する
- Author(s)
  原嶋奈々江、波里瑶子、門馬浩行、秋元美穂、竹永啓三、田島義証、原田守
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  パシフィコ横浜（横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24501331
[Presentation] ABT-263はヒト膵がん細胞のTRAILによるアポトーシスを増強する
- Author(s)
  波里瑶子、原嶋奈々江、門馬浩行、田島義証、原田守
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  パシフィコ横浜（横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24501331
[Presentation] 可溶性ST2は炎症性のがん微小環境を修飾し膵臓がんの腫瘍血管新生と増殖を抑制する
- Author(s)
  秋元美穂、原田守、竹永啓三
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  パシフィコ横浜（横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24501331
[Presentation] Bcl-2 family 阻害剤によるヒト膵癌細胞のTRAIL抵抗性の克服
- Author(s)
  波里瑶子、原嶋奈々江、門馬浩行、田島義証、原田守
- Organizer
  第18回日本がん免疫学会
- Place of Presentation
  ひめぎんホール（松山市）
- Year and Date
  2014-07-30 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-24501331
[Presentation] Pifithrin-, an inhibitor of HSP70, can increase the antitumor effects of hyperthermia against human prostate cancer cells
- Author(s)
  Mamoru Harada
- Organizer
  、The 6th ACHO & the 31st JCTM
- Place of Presentation
  福井県民ホールAOSSA（福井市）
- Year and Date
  2014-09-04 – 2014-09-06
- Invited
- Data Source
  KAKENHI-PROJECT-24501331
[Presentation] ：低酸素誘導因子 HIF 阻害によるヒト膵癌細胞のTRAIL感受性の増強
- Author(s)
  原嶋奈々江、門馬浩行、波里瑶子、秋元美穂、竹永啓三、原田守
- Organizer
  第18回日本がん免疫学会
- Place of Presentation
  ひめぎんホール（松山市）
- Year and Date
  2014-07-30 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-24501331
[Presentation] ABT-263はヒト前立腺癌PC3細胞のドセタキセル感受性を増強する
- Author(s)
  玉木宏樹、原嶋奈々江、原田守
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  パシフィコ横浜（横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24501331
[Presentation] シイタケ菌糸体抽出物とgemcitabineの併用はTregとMDSCを抑制することで相乗的な抗腫瘍効果を発揮す
- Author(s)
  石川悟、和知俊、松井保公、山口博史、原田
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  パシフィコ横浜（横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24501331
[Presentation] 抗がん剤やBRMによる免疫抑制の軽減と抗がんＴ細胞応答の誘導
- Author(s)
  原田守
- Organizer
  第52回日本癌治療学会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-08-28 – 2014-08-30
- Invited
- Data Source
  KAKENHI-PROJECT-24501331
[Presentation] Combination of low-dose and intermittent chemotherapy with cyclophosphamide and gemcitabine restores efficacy of anti-CD137 antibody therapy at the late tumor-bearing state
- Author(s)
  Harada M, Tamada K, Harashima N
- Organizer
  第43回日本免疫学会総会
- Place of Presentation
  国立京都国際会館（京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24501331
[Presentation] ヒト膵癌細胞に対するTRAILとchloroquine の併用効果の検討
- Author(s)
  門馬浩行、原嶋奈々江、波里瑶子、田島義証、原田守
- Organizer
  第18回日本がん免疫学会
- Place of Presentation
  ひめぎんホール（松山市）
- Year and Date
  2014-07-30 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-24501331

1. DE VELASCO Marco (20449838)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
2. UEMURA Hirotsugu (90213397)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
3. MINAMI Takafumi (70340809)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
4. YOSHIMURA Kazuhiro (20283757)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
5. 吉田裕樹 (40260715)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MUTA Hiromi (40325478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TANI Kenzaburo (00183864)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 岸原健二 (80214774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 松崎吾朗 (30229455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NAKAE Susumu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. OKANO Shinji

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
12. KOTANI Hitoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 川内秀之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 原嶋奈々江

# of Collaborated Projects: 0 results

# of Collaborated Products: 10 results
15. 相島慎一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 吉住朋晴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 副島雄二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 池上徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 前原喜彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 調憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 竹永啓三

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 秋元美穂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 田島義証

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 玉田耕治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 今村龍

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 須田貴司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HARADA Mamoru 原田 守

原田 守 ハラダ マモル

Research Projects

Research Products

Co-Researchers

腎細胞癌に対するマルチペプチド癌ワクチンの開発、複合免疫療法としての有用性の検討Ongoing

Principal Investigator

Project Period (FY)

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加齢に伴う免疫能の変化に立脚した化学療法との複合がん免疫療法の確立Principal InvestigatorOngoing

Principal Investigator

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Development of the HLA-A2 restricted multi-peptides vaccine for renal cell carcinoma.

Principal Investigator

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Development of multi-peptide tumor vaccine for renal cell carcinoma

Principal Investigator

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Effective anti-cancer immunotherapy by controling autophagyPrincipal Investigator

Principal Investigator

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Development of tailor made peptide vaccines for renal cell carcinoma

Principal Investigator

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Anti-cancer immunotherapy targeting toll-like receptors expressed on cancer cells and killer T cellsPrincipal Investigator

Principal Investigator

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Study on anti-cancer immunotherapy targeting a tumor marker, SCCAPrincipal Investigator

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Clinical study of cancer immunotherapy with dendritic cells pulsed with Taylor made peptides

Principal Investigator

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CD4陽性ヘルパーT細胞に認識される上皮性癌抗原遺伝子の同定Principal Investigator

Principal Investigator

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Review Section

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Identification of epithelial cancer-associated antigens and application to cancer vaccinePrincipal Investigator

Principal Investigator

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Apaf1欠損アポトーシス抵抗性細胞における癌化と細胞死の解析

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

特異遺伝子欠損マウスにおける免疫応答異常の解析

Principal Investigator

Project Period (FY)

HARADA Mamoru 原田守

原田守ハラダマモル

[Journal Article] Transfection of poly(I:C) can induce reactive oxygen species-triggered apoptosis and interferon--mediated growth arrest in human renal cell carcinoma cells via innate adjuvant receptors and the 2-5A system2014