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UEDE Toshimitsu  上出 利光

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… Alternative Names

UEDA Toshimitsu  上出 利光

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Researcher Number 00160185
Other IDs
Affiliation (based on the past Project Information) *help 2014: 北海道大学, 遺伝子病制御研究所, 教授
2009 – 2012: Hokkaido University, 遺伝子病制御研究所, 教授
2000 – 2006: Hokkaido Univ., Inst.Genet.Med., Prof., 遺伝子病制御研究所, 教授
2003 – 2004: 北海道大学, 遺伝子病制御研究所・分子免疫部門, 教授
2003: 北海道大学, 遺伝子疾病制御研究所, 教授 … More
2002: 遺伝子病制御研究所, 教授
1999: 免疫科学研究所, 教授
1991 – 1999: 北海道大学, 免疫科学研究所, 教授
1997: 北海道大学, 免疫学研究所, 教授
1993: 北海道大学, 免疫科学研, 教授
1992: 北海道大学, 免疫科学研究所 教授
1991: Hokkaido University Institute for Immunology, Department of Pathogenesis Profess, 免疫研究所免疫病態部門, 教授
1990: 札幌医科大学, 医学部, 助教授
1990: Dept. Pathology, Sapporo Medical College, 病理学第一講座, 助教授
1989: 札幌医科大学, 医学部, 講師
1986 – 1987: 札幌医科大学, 医学部, 講師
1986: 札幌医大, 医学部, 助手
1986: 札幌医科大学, 講師 Less
Review Section/Research Field
Principal Investigator
Experimental pathology / Biological Sciences / Experimental pathology / General surgery / Human pathology
Except Principal Investigator
Circulatory organs internal medicine / General surgery / Experimental pathology / Plastic surgery / Urology … More / Anesthesiology/Resuscitation studies / Digestive surgery / Living organism molecular science / Digestive surgery Less
Keywords
Principal Investigator
血管内皮 / 接着分子 / 転移 / オステオポンチン / インテグリン / リンパ球遊走因子 / 細胞接着 / CTLA4 / アポトーシス / CTLA4Ig … More / CD8陽性T細胞 / CD44v / アデノウイルスベクター / サイトカイン / 免疫学的寛容 / Eta-1 / RGD / ステロイド / 胸腺細胞 / 遺伝子導入マウス / steroid / キラーT細胞 / 癌拒絶 / 接着因子 / R2ー1A6抗原 / VLA-4 / 浸潤 / R2-1A6抗原 / T細胞遊走因子 / Fcr受容体 / B7-1a / 変異型補助シグナル分子 / 補助シグナル分子 / B7-1 / 生存曲線 / 腫瘍免疫 / B7 / Fas / CD28 / 遺伝子導入 / 異種移植 / Concordant / 遺伝子治療 / CD40Ig / CTLA41Ig / FK778 / 肝移植 / 心移植 / ラット / ハムスター / 肝臓 / 心臓 / 炎症 / 細胞外マトリックス / Matricellular protein / α9β1インテグリン / 抗体医薬 / 難治性炎症性疾患 / アルファ9インテグリン / リンパ管上皮 / S1P / テナーシンC / ケモカイン受容体 / リンパ球動員阻害 / matricellular protein / α9インテグリン / マクロファージ / CSF-1 / TGF-β / Treg / 再循環障害 / 多臓器不全 / Reperfusion Injury / Multiple Organ Failure / Cytokine / Adhesion Molecule / Endothelium / 臓器移植 / 拒絶反応 / 可溶性接着分子 / 補助シグナル / アナヅィー / アナジィー / Transplantation / Rejection / Cell Adhesion Molecule / Immunological Torerance / 細胞接着部位 / Tリンパ球 / 自己免疫 / Cell Binding Site / Integrin / 樹状細胞 / 小腸移植 / 腎移植 / 皮膚移植 / passenger leukocyte / 肢移植 / GM-CSF / DST / キメリズム / dendritic cells / small bowel transplantation / Kidney transplantation / Adenovirus vector / アネキシンV / 分化 / apoptosis / thymocytes / transgenic mice / 癌 / 予後 / 動脈硬化 / 肉芽腫 / アレル / トランスジェニックマウス / iNOS / ELISA / β1インテグリン / 細胞遊走 / osteopontin / cancer / prognosis / atherosclerosis / カスペース / Thymocyte / Apoptosis / Transgenic mice / caspase / 中和抗体 / 関節リウマチ / siRNA / 脱接着 / 癌転移 / RNAアプタマー / Osteopontin / neutralizing antibody / rheumatoid arthritis / integrin / Bリンパ球 / 単クローン抗体 / B細胞活性化 / 悪性リンパ腫 / モノクローナル抗体 / 小型静止期B細胞 / マントルゾーン / 活性化大型B細胞 / 胚中心 / Monoclonal antibody / human B lymphocyte / Lymphocyte-differnentiation antigen / Leukocyte-common antigen … More
Except Principal Investigator
CTLA4Ig / CD40Ig / T細胞 / 遺伝子治療 / オステオポンチン / シグナル伝達 / 免疫寛容 / ラット / IL-2 / Osteopontin / AdCTLA4Ig / AdCD40Ig / Monkey / Gene therapy / T細胞活性化 / CD28 / Co-stimulation / IL-2レセプター / 酸化ストレス / CTLA4 / 肝移植 / 臓器移植 / 腫瘍抗原 / がん遺伝子 / 接着分子 / 血管新生 / VEGF / 副刺激 / ex-vivo / Clamp Technique / Cre / loxP / 免疫抑制 / Transplantation / Adeno virus / Costimulatory signal / Rejection / Tolerance / Rodents / NF-κB / DHMEQ / 小腸移植 / OPN / siRNA / RNA / ICAM-1 / E-カドヘリン / セレクチンファミリー / CD23 / 硫酸化糖鎖 / CEA / チロシンホスファターゼ / TCR構造異常 / HS1 / CD45 / Syk / Jak / Co-stimulator / 心筋組織レニン・アンジオテンシン系 / 白血球活性化機構 / T細胞レセプター / 抗腫瘍免疫 / CD3結合分子 / セリン・スレオニンキナーゼ / Jak3欠損マウス / TCR-CD_3複合体 / Srcファミリーキナーゼ / 遺伝子欠損マウス / CD45フォスファターゼ / 増殖シグナル / 国際学術 / 海外派遣 / ウイルス発癌 / 構造生物学 / ゲノム医学 / 癌治療 / 化学発癌 / 細胞接着 / 細胞周期 / 副信号 / B7-1 / B7-2 / ACBM / B細胞 / 心移植 / 肝臓 / 心臓 / costimulatory pathway / CAR / ヒストン脱アセチル化酵素阻害剤 / アデノウイルスベクター / FK228 / 尿路結石 / マクロファージ / メタボリックシンドローム / ゲノムワイド解析 / ミトコンドリア / ゲノム解析 / 細胞障害 / サル / マルチプレックス解析 / アディポネクチン / キラーT細胞活性化因子 / 分化抗原 / キラーT細胞クローン / 癌特異抗原 / ブタノール抗原 / トランスフェクション / 癌免疫治療 / 胸腺細胞 / 細胞外基質 / cDNAクロ-ニング / 単クロ-ン抗体 / thymocytes / adhesion molecules / extracelluar matrix / リンパ球増殖分化 / 抗原受容体 / サイトカイン / 細胞死 / 補助刺激因子 / 骨髄ストローマ / サイトカイン受容体 / 補助因子受容体 / リンパ球初期分化 / クローナル除去 / lymphocyte lineage / signal transduction / tolerance / antigen receptor / cytokine / apoptosis / costimulatory factor / 胸部大動脈瘤 / 開心手術 / 術後呼吸不全 / 揮発性麻酔薬 / 再潅流障害 / 再灌流障害 / 人工心肺 / BAL / 細灌流障害 / Adhesion Molecule / Respiratory Failure / Dissecing Thoracic Aortic Aneurysm / Coronary Artery Bypass Graft / Cardiopulmonary Bypass / Volatile Anesthetics / 心筋再構築 / 心筋細胞移植 / CTLA41g / Cardiac Remodeling / Angiogenesis / T cells / Myocyte transplantation / 移植免疫 / INF-γ / CD8 / CD4 / T細胞Killer活性 / transplantation / gene therapy / costimulatory / カニクイザル / 同種手の移植 / 免疫抑制剤 / 同種手移植 / CD3 immunotoxin / Hand allo-grafting / immunosuppression / 神経端側吻合 / アデノウィルスベクター / 神経再生 / 組み換え遺伝子 / アデノウィルスヴェクター / 組み替え遺伝子 / end to side / adenovirus vector / nerve regeneration / Lac Z / costimulatory signal / CD40 / anti-human monoclonal antibody / 4D11 / Kidney transplantation / 免疫抑制療法 / SDF-1 / HO-1 / モノクローナル抗体 / Leflunomide / FK779 / 異種心移植 / FK778 / タクロリムス / プログラフ / 腎移植 / MHCクラス2抗原 / 副刺激経路 / anergy / 肝臓移植 / Adenovirus / 骨髄由来幹細胞 / 細胞移植 / 心不全 / 心筋再生 / 免疫学的拒絶 / Bone marrow derived stem cell / Cell transplantation / Heart failure / Neovascalarization / GVHD / Immunological Anergy / T cell / 転移 / concanavalin A / 肝炎 / オリゴヌクレオチド / Concanavalin A / 癌転移 / RNAi / 炎症疾患 / リン酸化糖タンパク質 / metastasis / concanavarin A / hepatitis / oligonucleotide / 虚血再灌流傷害 / アデノウイルス / 拒絶反応 / マウス / 小腸 / 虚血再灌流障害 / Small bowel transplantation / Costimulatory signals / Immunosuppression / Ischemia / reperfusion / NF-kB / ウイルス発がん / 発がんプロモ-タ- / がん抑制遺伝子 / T細胞の増殖 / 免疫応答 / リンフォカイン / Oncogene / Viral Oncogene / Tumor Promoter / Tumor Supressor Gene / Tumor Antigen / T Cell Growth / Immune Desponse / Lymphokine Less
  • Research Projects

    (43 results)
  • Research Products

    (78 results)
  • Co-Researchers

    (130 People)
  •  Integrated elucidation of the urinary stone formation mechanism considered from heredity and environment factors, and development of the new therapeutic medicines

    • Principal Investigator
      KOHRI KENJIRO
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Urology
    • Research Institution
      Nagoya City University
  •  新規マクロファージ亜群の同定とその生体内自己免疫反応制御における意義Principal Investigator

    • Principal Investigator
      上出 利光
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  Molecular basis for the functional regulation of intractable inflammatory disorders by OsteopontinPrincipal Investigator

    • Principal Investigator
      UEDE Toshimitsu
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Hokkaido University
  •  Molecular basis for the control of intractable diseases through manipulation of osteopontin function.Principal Investigator

    • Principal Investigator
      UEDE Toshimitsu
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Experimental pathology
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Development of a gene therapy based new strategy in small bowel transplantation

    • Principal Investigator
      FURUKAWA Hiroyuki
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Hokkaido University
  •  Investigation of regulatory mechanism of homeostasis using functional nucleic acids.

    • Principal Investigator
      KOMATSU Yasuo, 大塚 榮子
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
  •  遺伝子治療による臓器移植免疫寛容導入:ヒストン脱アセチル化酵素阻害薬の併用効果

    • Principal Investigator
      古川 博之
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      Hokkaido University
  •  Studies on New Strategy for Myocardial Infarction and Heart Failure by Bone-Marrow Derived Stem Cell Transplantation

    • Principal Investigator
      KITABATAKE Akira
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Hokkaido University
  •  Molecular analysis of steroid-induced apoptosis and its relevance to disease pathogenesis.Principal Investigator

    • Principal Investigator
      UEDE Toshimitsu
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Hokkaido University
  •  The induction of tolerance using the brand new gene therapy in transplantation setting and clarification of the mechanism.

    • Principal Investigator
      FURUKAWA Hiroyuki
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Hokkaido University
  •  Composite allo-tissue grafting by the induction of selective immunotolerance using adenovirus vectoe

    • Principal Investigator
      SHIBATA Minoru
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Plastic surgery
    • Research Institution
      NIIGATA UNIVERSITY
  •  Nerve regeneration tracing using adenovirus vector after end-to-side nerve coaptation

    • Principal Investigator
      SHIBATA Minoru
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      NIIGATA UNIVERSITY
  •  Tolerance induction by gene therapy in organ transplantation

    • Principal Investigator
      TODO Satoru
    • Project Period (FY)
      2001 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      General surgery
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  B7/Fasキメラ遺伝子導入による抗腫瘍免疫遺伝子療法の開発Principal Investigator

    • Principal Investigator
      上出 利光
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  CD40Ig遺伝子導入による同種臓器移植拒絶反応の制御

    • Principal Investigator
      FURUKAWA Hiroyuki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      Hokkaido University
  •  Concordant異種移植における遺伝子導入による免疫反応制御の研究Principal Investigator

    • Principal Investigator
      上出 利光
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      Hokkaido University
  •  補助シグナル分子遺伝子発現系を用いた抗癌免疫系増強法の開発Principal Investigator

    • Principal Investigator
      上出 利光
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Hokkaido University
  •  Recovery from the Cardiac Remodeling by Neovascularization under the Immunologic Annergy Induced by CTLA4Ig

    • Principal Investigator
      KITABATAKE Akira
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Hokkaido University
  •  変異型補助シグナル分子遺伝子導入による癌増殖及び転移抑制法の検討Principal Investigator

    • Principal Investigator
      上出 利光
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Hokkaido University
  •  The role of DIG-1 gene steroid-induced apoptosis.Principal Investigator

    • Principal Investigator
      UEDE Toshimitsu
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Experimental pathology
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Analysis of regulation of host defense response by osteopopontin and its applocation to diagnosis and therapy strategyPrincipal Investigator

    • Principal Investigator
      UEDE Toshimitsu
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Experimental pathology
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  アメリカ大陸を中心としたがん研究先進グループとの研究交流

    • Principal Investigator
      YAMAMOTO Tadashi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo
  •  新しいCTLA4結合分子、ACBMのcDNA単離とその機能解析

    • Principal Investigator
      村上 正晃
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  T細胞活性化のシグナル伝達

    • Principal Investigator
      斉藤 隆
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Chiba University
  •  T細胞活性化のシグナル伝達

    • Principal Investigator
      斉藤 隆
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Chiba University
  •  Induction of tolerance and suppression of rejection by transfer of immature hepatic dendritic cells.Principal Investigator

    • Principal Investigator
      UEDE Toshimitsu
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Experimental pathology
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  T細胞活性化のシグナル伝達

    • Principal Investigator
      SAITO Takashi
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Chiba University
  •  心筋梗塞急性期における白血球活性化および接着分子発現機構に関する検討

    • Principal Investigator
      OKAMOTO Hiroshi
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Hokkaido University
  •  Modification of T cell responses by Eta-1 and pathogenesis of autoimmune disease.Principal Investigator

    • Principal Investigator
      UEDA Toshimitsu
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Hokkaido Universitiy
  •  Role of Adhesion molecule in respiratory failure after surgery for dissecing thoracic aortic aneurysms or coronary artery bypass graft surgery

    • Principal Investigator
      MAYUMI Takahisa
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hokkaido University
  •  消化器癌における細胞接着分子の遺伝子および機能解析と診断応用

    • Principal Investigator
      谷内 昭
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  Molecular mechnisms of immune tolerance.

    • Principal Investigator
      HIRANO Toshio
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  癌拒絶におけるキラーT細胞特異的遊走因子の関与とその分子生物学的研究Principal Investigator

    • Principal Investigator
      上出 利光
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hokkaido University
  •  Immunological regulation of multiple organ failure by reperfusion injury.Principal Investigator

    • Principal Investigator
      UEDE Toshimitsu
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Hokkaido University
  •  Induction of immunological tolerance by cell adhesion moleculerelated substances.Principal Investigator

    • Principal Investigator
      UEDE Toshimitsu
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Hokkaido University
  •  癌拒絶におけるキラ-T細胞特異的遊走因子の関与とその分子生物学的研究Principal Investigator

    • Principal Investigator
      上出 利光
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hokkaido University
  •  癌拒絶におけるキラ-T細胞特異的遊走因子の関与とその分子生物学的研究Principal Investigator

    • Principal Investigator
      上出 利光
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  癌拒絶におけるキラーT細胞特異的遊走因子の関与とその分子生物学的研究Principal Investigator

    • Principal Investigator
      上出 利光
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  Significance of adhesion molecules in differentiation and activation of thymocytes.Principal Investigator

    • Principal Investigator
      MATSUURA Akihiro, 上出 利光
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Sapporo Medical College
  •  Information Exchange on Cancer Research with North American Countries

    • Principal Investigator
      YAMAGUCHI Nobuo, 河井 貞明
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      The Institute of Medical Science, The University of Tokyo
  •  Analysis of mechanism that control B cell activation by using monoclonal antibodies.Principal Investigator

    • Principal Investigator
      UEDE Toshimitsu
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Human pathology
    • Research Institution
      Sapporo Medical College
  •  腫瘍抗原の発現と免疫系の認識に関する分子免疫学的解析

    • Principal Investigator
      谷口 克
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Chiba University
  •  人癌増殖局所における免疫応答の解析

    • Principal Investigator
      菊地 浩吉
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Sapporo Medical University

All 2012 2011 2010 2009 2007 2006 2005 2004

All Journal Article Presentation Book Patent

  • [Book] 医科免疫学2010(改訂第6版)2010

    • Author(s)
      上出利光
    • Total Pages
      494
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Book] 医科免疫学2010(改訂第6版),163-184免疫反応の制御機構(菊地浩吉、上出利光、小野江和則編.470頁)2010

    • Author(s)
      上出利光
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Book] 医科免疫学2010(改訂第6版)2010

    • Author(s)
      上出利光
    • Total Pages
      494
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PUBLICLY-22021003
  • [Book] 炎症・再生医学辞典,106-108 オステオポンチン(松島綱治、西脇徹編、)2009

    • Author(s)
      森本純子, 上出利光
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Book] B型ウイルス肝炎の分子免疫学。HBV感染と免疫機序。肝炎とOPN(osteopontin)/Eta-1(early T lymphocyte activation-1)2004

    • Author(s)
      上出利光
    • Total Pages
      5
    • Publisher
      日本臨牀
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15310157
  • [Journal Article] Osteopontin regulates interleukin-17 production in hepatitis.2012

    • Author(s)
      Diao H, Liu X, Wu Z, Kang L, Cui G, Morimoto J, Denhardt D, Rittling S, Iwakura Y, Uede T, Li L
    • Journal Title

      Cytokine

      Volume: 60 Pages: 129-137

    • DOI

      10.1016/j.cyto.2012.06.287

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Journal Article] Extracellular matrix protein Tenascin-C is required in the bone marrow microenvionment primed for hematopoietic regeneration2012

    • Author(s)
      Nakamura-Ishizu A, Okuno Y, Omatsu Y, Okabe K, Morimoto J, Uede T, Nagasa- wa T, Suda T, Kubota Y
    • Journal Title

      Blood

      Volume: 119 Pages: 5429-37

    • DOI

      10.1182/blood-2011-11-393645

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390113, KAKENHI-PROJECT-21689047, KAKENHI-PROJECT-22390096, KAKENHI-PUBLICLY-23111536, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23790533, KAKENHI-PROJECT-24790983, KAKENHI-PLANNED-22122002, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111003
  • [Journal Article] Osteopontin is critical to determine symptom severity of influenza through the regulation of NK cell population.2012

    • Author(s)
      Sato K, Iwai A, Nakayama Y, Morimot- o J, Takada A, Maruyama M, Kida H, Uede T, Miyazaki T
    • Journal Title

      Biochemical and Biophysical Research Communication

      Volume: 417 Pages: 274-279

    • DOI

      10.1016/j.bbrc.2011.11.100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390113, KAKENHI-PROJECT-23590559
  • [Journal Article] α9β1 integrin-mediated signaling serves as an intrinsic regulator of pathogenic Th17 cell generation2011

    • Author(s)
      Kanayama M, Morimoto J, Matsui Y, I- kesue M, Danzaki K, Kurotaki D, Ito K, Yoshida T, Uede T
    • Journal Title

      JOURNAL OF IMMUNOLOGY

      Volume: 187 Pages: 5851-5864

    • DOI

      10.4049/jimmunol.1101524

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390113, KAKENHI-PROJECT-21590368
  • [Journal Article] Crucial role of the cryptic peitope SLAYGLR within osteopontin in renal crystal formation of mice2011

    • Author(s)
      Hamamoto S, Yasui T, Okada A, Hirose M, Matsui Y, Kon S, Sakai F, Kojima Y, Hayashi Y, Tozawa K, Uede T, Ko- hri K
    • Journal Title

      J Bone Mine Res

      Volume: 26 Pages: 2967-2977

    • DOI

      10.1002/jbmr.495

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390113, KAKENHI-PROJECT-21791517, KAKENHI-PUBLICLY-22021003, KAKENHI-PROJECT-23249074, KAKENHI-PROJECT-23592375
  • [Journal Article] Osteopontin modulates the generation of memory CD8+T cells during influenza virus infection2011

    • Author(s)
      Morimoto J, Sato K, Nakayama Y, Kim- ura C, Kajino K, Matsui Y, Miyazaki T, Uede T
    • Journal Title

      J Immunol

      Volume: 187 Pages: 5671-83

    • DOI

      10.4049/jimmunol.1101825

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Journal Article] Prevention of experimental autoimmune uveoretinitis by blockade of osteopontin with small interfere-ing RNA2010

    • Author(s)
      Iwata D, Kitamura M, Kitaichi N, Sa- ito Y, Kon S, Namba K, Morimoto J, Ebihara A, Kitamei H, Yoshida K, Is- hida S, Ohno S, Uede T, Onoe K, Iwa- buchi K
    • Journal Title

      Exp Eye Res

      Volume: 90 Pages: 41-48

    • DOI

      10.1016/j.exer.2009.09.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Journal Article] An- tigen specific induction of osteopo- ntin contributes to the chronificat- ion of allergic contact dermatitis2010

    • Author(s)
      Seier AM, Renkl AC, Chulz GS, Uebele T, Ahrens T, Sindrilaru A, Iben S, Liaw L, Kon S, Uede T, Weiss JM
    • Journal Title

      Am J Pathol

      Volume: 176 Pages: 246-258

    • DOI

      10.2353/ajpath.2010.090488

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Journal Article] The differential amino acid require- ment within osteopontin in alpha4and alpha9 integrin-mediated cell binding and migration2009

    • Author(s)
      Ito K, Kon S, Nakayama Y, Kurotaki D, Saito Y, Kanayama M, Kimura C, Diao H, Morimoto J, Matsui Y, Uede T
    • Journal Title

      Matrix Biol

      Volume: 28 Pages: 11-19

    • DOI

      10.1016/j.matbio.2008.10.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Journal Article] Alpha9 integrin and its lignads con- stitute critical joint microenviron- ments for development of autoimmune arthritis2009

    • Author(s)
      Kanayama M, Kurotaki D, Morimoto J, Asano T, Matsui Y, Nakayama Y, Saito Y, Ito K, Kimura C, Iwasaki N, Suzu ki K, Harada T, Li HM, Uehara J, Mi- yazaki T, Minami A, Kon S, Uede T
    • Journal Title

      J Immunol

      Volume: 182 Pages: 8015-8025

    • DOI

      10.4049/jimmunol.0900725

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Journal Article] Loss of osteopontin perturbs the epithelial-mesenchymal transition in an injured mouse lens epithelium.2007

    • Author(s)
      S.Saika, K.Shirai, O.Yamanaka, KI.Miyazaki, Y.Okada, A.Kitano, KC.Flanders, S.Kon, T.Uede, WW.Kao, SR.Rittling, DT.Denhardt, Y.Ohnishi
    • Journal Title

      Lab Invest. 87

      Pages: 130-138

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] Suppression of the bacterial antigen-specific T cell response and the dendritic cell migration to the lymph nodes by osteopontin.2007

    • Author(s)
      MD.Begum, M.Umemura, S.Kon, A.Yahagi, S.Hamada, K.Oshiro, K.Gotoh, A.Nishizono, T.Uede, G.Matsuzaki
    • Journal Title

      Microbiol Immunol. 51

      Pages: 135-147

    • NAID

      10020282178

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] The role of osteopontin in tendon tissue remodeling after denervation-induced mechanical stress deprivation.2007

    • Author(s)
      N.Mori, T.Majima, N.Iwasaki, S.Kon, K.Miyakawa, C.Kimura, K.Tanaka, DT.Denhardt, S.Rittling, A.Minami, T.Uede
    • Journal Title

      Matrix Biol. 26

      Pages: 42-53

    • NAID

      120000961947

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] Critical role of inducible costimulator signaling in the development of arteriosclerosis.2006

    • Author(s)
      H.Kosuge, JI.Suzuki, G.Haraguchi, N.Koga, Y.Maejima, M.Inobe, M.Isobe, T.Uede
    • Journal Title

      Arterioscler Thromb Vasc Biol. 26

      Pages: 2660-2665

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] Role of the integrin-binding protein osteopontin in lymphatic metastasis of breast cancer.2006

    • Author(s)
      AL.Allan, R.George, SA.Vantyghem, MW.Lee, NC.Hodgson, CJ.Engel.RL.Holliday, DP.Girvan, LA.Scott, CO.Postenka, W.Alkatib, LW.Stitt, T.Uede, AF.Chambers, AB.Tuck
    • Journal Title

      Am J Pathol. 169

      Pages: 233-246

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] Osteopontin participates in Thl- mediated host resistance against nonlethal malaria parasite plasmodium chabaudi chabaudi infection in mice.2006

    • Author(s)
      Y.Maeno, S.Nakazawa, N.Yamamoto, M.Shinzato, S.Nagashima, K.Tanaka, J.Sasaki, SR.Rittling, DT.Denhart, T.Uede, K.Taniguchi
    • Journal Title

      Infect Immun. 74

      Pages: 2423-2427

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] High plasma concentrations of osteopontin in patients with interstitial pneumonia.2005

    • Author(s)
      J.Kadota, S.Mizunoe, K.Mito, H.Mukae, S.Yoshioka, K.Kawakami, Y.Koguchi, K.Fukushima, S.Kon, S.Kohno, A.Saito, T.Uede, M.Nasu
    • Journal Title

      Respir Med. 99

      Pages: 111-117

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] Circulating interleukin-18 and osteopontin are useful to evaluate disease activity in patients with tuberculosis.2005

    • Author(s)
      S.Inomata, N.Shijubo, S.Kon, M.Maeda, G.Yamada, N.Sato, S.Abe, T.TUede
    • Journal Title

      Cytokine. 30

      Pages: 203-211

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] Persistent hyperplastic primary vitreous in transgenic mice expressing IE180 of the pseudorabies virus.2005

    • Author(s)
      S.Taharaguchi, K.Yoshida, Y.Tomioka, S.Yoshino, T.Uede, E.Ono
    • Journal Title

      Invest Ophthalmol Vis Sci. 46

      Pages: 1551-1556

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] Mechanism of macrophage activation by chitin derivatives.2005

    • Author(s)
      T.Mori, M.Murakami, M.Okumura, T.Kadosawa, T.Uede, T.Fujinaga
    • Journal Title

      J Vet Med Sci. 67

      Pages: 51-56

    • NAID

      130000448459

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] Osteopontin/Eta-1 upregulated in Crohn's disease regulates the Thl immune response.2005

    • Author(s)
      T.Sato, T.Nakai, N.Tamura, S.Okamoto, K.Matsuoka, A.Sakuraba, T.Fukushima, T.Uede, T.Hibi
    • Journal Title

      Gut. 54

      Pages: 1254-1262

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] Cre/loxP-mediated CTLA4IgG gene transfer induces clinically relevant immunosuppression via on-off gene recombination in vivo.2005

    • Author(s)
      A.Izawa, K.Sano, M.Takehara, M.Inobe, J.Suzuki, H.Imamura, M.Takahashi, U.Ikeda, M.Isobe, T.Uede
    • Journal Title

      Cardiovasc Res. 69

      Pages: 289-297

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] CD24 expression causes the acquisition of multiple cellular properties associated with tumor growth and metastasis.2005

    • Author(s)
      P.Baumann, N.Cremers, F.Kroese, G.Orend, R.Chiquet-Ehrismann, T.Uede, H.Yagita, JP.Sleeman
    • Journal Title

      Cancer Res. 65

      Pages: 10783-10793

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] Osteopontin functionally activates dendritic cells and induces their differentiation towards a Th-1 polarizing phenotype.2005

    • Author(s)
      AC.Renkl, J.Wussler, T.Ahrens, K.Thoma, S.Kon T.Uede, SF.Martin, JC.Simon, JM.Weiss
    • Journal Title

      Blood. 106

      Pages: 946-955

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] Gene Therapy-Mediated CD40L and CD28 Co-stimulatory Signaling Blockade plus Transient Anti-xenograft Antibody Suppression Induces Long-Term Acceptance of Cardiac Xenografts2004

    • Author(s)
      Hua N, Yamashita K, Hashimoto T, Masunaga T, Fujita M, Furukawa H, Uede T, Todo S
    • Journal Title

      Transplantation 78(10)

      Pages: 1463-1470

    • Data Source
      KAKENHI-PROJECT-13854019
  • [Journal Article] Functional role of death associated protein 3 (DAP3) in anoikis.2004

    • Author(s)
      T.Miyazaki, M.Shen, D.Fujikura, N.Tosa, S.Kon, T.Uede, JC.Reed
    • Journal Title

      J Biol Chem. 279

      Pages: 44667-44672

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] In vitro and in vivo effects of the overexpression of osteopontin on osteoblast differentiation using a recombinant adenoviral vector.2004

    • Author(s)
      H.Kojima, T.Uede, T.Uemura
    • Journal Title

      J Biochem. 136

      Pages: 377-386

    • NAID

      10016202314

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] Hepatitis/hepatocellular carcinoma and OPN/Eta-12004

    • Author(s)
      Uede, T., et al.
    • Journal Title

      Nippon Rinsho. Review 62 Suppl 8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310157
  • [Journal Article] Effect of osteopontin alleles on beta-grucan induced granuloma formation in the mouse liver.2004

    • Author(s)
      K.Tanaka.J.Morimoto, S.Kon, C.Kimura, M.Inobe, H.Diao, G.Hirschfeld, J.M.Weiss, T.Uede
    • Journal Title

      Am J Pathol. 164

      Pages: 567-575

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] Osteopontin as a positive regulator in the osteoclastogensis of arthritis.2004

    • Author(s)
      T.Ishii, S.Ohshima, T.Ishida, T.Mima, Y.Tabunoki, H.Kobayashi, M.Maeda, T.Uede, L.Liaw, N.Kinoshita, I.Kawase, Y.Saeki
    • Journal Title

      Biochem Biophys Res Commun. 316

      Pages: 809-815

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] Mice with osteopontin deletion remain predisposed to collagen-induced arthritis.2004

    • Author(s)
      T.Ishii, S.Ohshima, T.Ishida, I.Kawase, T.Mima, Y.Tabunoki, H.Kobayashi, M.Maeda, T.Uede, L.Liaw, N.Kinoshita, Y.Saeki
    • Journal Title

      Arthritis Rheum. 50

      Pages: 669-671

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] Role of osteopontin in cardiac fibrosis and remodeling in angiotensin II-induced cardiac hypertrophy.2004

    • Author(s)
      Y.Matsui, N.Jia, H.Okamoto, S.Kon, H.Onozuka, M.Akino, K.Liu, J.Morimoto, SR.Rittling, D.Denhardt, A.Kitabatake, T.Uede
    • Journal Title

      Hypertension. 43

      Pages: 1195-1201

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] Osteopontin as a mediator of NKT cell function in T cell-mediated liver diseases.2004

    • Author(s)
      H.Diao, S.Kon, K.Iwabuchi, C.Kimura, J.Morimoto, D.Ito, T.Segawa, M.Maeda, J.Hamuro, T.Nakayama, M.Taniguchi, H.Yagita, L.V.Kaer, K.Onoe, D.Denhardt, S.Rittling, T.Uede
    • Journal Title

      Immunity. 21

      Pages: 539-550

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Journal Article] Stromal Cell-Derived Factor-1 and CX CR4 Interaction Is Critical for Development of Transplant Arteriosclerosis2004

    • Author(s)
      Sakihama H, Masunaga T, Yamashita K, Hashimoto T, Inobe M, Todo S, Uede T
    • Journal Title

      Circulation 110

      Pages: 2924-2930

    • Data Source
      KAKENHI-PROJECT-13854019
  • [Journal Article] Osteopontin as a mediator of NKT cell function in T cell-mediated liver diseases.2004

    • Author(s)
      Diao, H., H, Van Kaer L, Onoe K, Denhardt DT, Rittling S, Uede T.et al.
    • Journal Title

      Immunity. 21(4)

      Pages: 539-550

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310157
  • [Journal Article] Osteopontin affects the persistence of beta-glucan-induced hepatic granuloma formation and tissue injury through two distinct mechanisms.2004

    • Author(s)
      J.Morimoto, M.Inobe, C.Kimura, S.Kon, H.Diao, M.Aoki, T.Miyazaki, DT.Denhardt, S.Rittling, T.Uede
    • Journal Title

      Int Immunol. 16

      Pages: 477-488

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Patent] 抗α9インテグリン抗体とその用途2006

    • Inventor(s)
      黒滝大翼, 金山剛士, 今 重之, 上出利光
    • Industrial Property Rights Holder
      (株)ジーンテクノサイエンス
    • Filing Date
      2006-01-12
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Patent] オステオポンチンsiRNA2006

    • Inventor(s)
      齋藤善也, 今 重之, 上出利光
    • Industrial Property Rights Holder
      (株)ジーンテクノサイエンス
    • Filing Date
      2006-12-11
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Patent] 細胞外マトリックスタンパク質のアミノ酸配列RGDに対する抗体および製法と用途2006

    • Inventor(s)
      今 重之, 木村千恵美, 上出利光
    • Industrial Property Rights Holder
      (株)ジーンテクノサイエンス
    • Filing Date
      2006-10-26
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Patent] 抗ヒトα9インテグリン抗体とその用途2006

    • Inventor(s)
      金山剛士, 黒滝大翼, 今 重之, 上出利光
    • Industrial Property Rights Holder
      (株)ジーンテクノサイエンス
    • Filing Date
      2006-07-12
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Patent] 抗ヒトα9インテグリン抗体とその用途2006

    • Inventor(s)
      金山剛士, 黒滝大翼, 今 重之, 上出利光
    • Industrial Property Rights Holder
      (株)ジーンテクノサイエンス
    • Filing Date
      2006-07-12
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Patent] オステオポンチンsiRNA2006

    • Inventor(s)
      齋藤善也, 今 重之, 上出利光
    • Industrial Property Rights Holder
      (株)ジーンテクノサイエンス
    • Filing Date
      2006-12-11
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Patent] 抗α9インテグリン抗体とその用途2006

    • Inventor(s)
      黒滝大翼, 金山剛士, 今 重之, 上出利光
    • Industrial Property Rights Holder
      (株)ジーンテクノサイエンス
    • Filing Date
      2006-01-12
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Patent] 細胞外マトリックスタンパク質のアミノ酸配列RGDに対する抗体および製法と用途2006

    • Inventor(s)
      今 重之, 木 村 千 恵 美, 上出利光
    • Industrial Property Rights Holder
      (株)ジーンテクノサイエンス
    • Filing Date
      2006-10-26
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Patent] 抗α9インテグリン抗体2005

    • Inventor(s)
      黒滝大翼, 今重之, 上出利光
    • Industrial Property Rights Holder
      (株)ジーンテクノサイエンス
    • Filing Date
      2005-01-13
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Patent] オステオポンチンsiRNA2005

    • Inventor(s)
      齋藤善也, 今 重之, 小松康雄, 上出利光
    • Industrial Property Rights Holder
      生化学工業(株), (株)ジーンテクノサイエンス
    • Filing Date
      2005-04-12
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Patent] 腱・靱帯の劣化予防剤、治療剤2004

    • Inventor(s)
      森 律明, 岩崎倫政, 三浪明男, 今 重之, 上出利光, 前田雅弘
    • Industrial Property Rights Holder
      (株)免疫生物研究所, (株)ジーンテクノサイエンス
    • Filing Date
      2004-11-04
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Patent] 免疫担当細胞活性化阻害剤およびその用途2004

    • Inventor(s)
      今 重之, 上出利光, ディオコウエン
    • Industrial Property Rights Holder
      (株)免疫生物研究所, (株)ジーンテクノサイエンス
    • Filing Date
      2004-05-21
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209014
  • [Presentation] Regulation of autoimmunity by interaction of matricellular proteins and their integrin receptors.2012

    • Author(s)
      Toshimitsu Uede
    • Organizer
      Medical Science Forum Tokyo 2012 on Immunity for the Control of Autoimmune Diseases
    • Place of Presentation
      東京大学(東京)
    • Invited
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Presentation] Tissue matoricellular proteins regulate effector Tcells from draining lymph nodes via alpha9integrin-signaling.2012

    • Author(s)
      Toshimitsu Uede
    • Organizer
      FASEB summer research conference Osteopontin Biology
    • Place of Presentation
      Vermont Academy(USA)
    • Invited
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Presentation] The role of splen-ic CD103+CD8α+cDCs in the inductionof CTL responses during respiratory virus infection2012

    • Author(s)
      Morimoto J, Kajino K, Danzaki K, Na- kayama Y, Uede T
    • Organizer
      99th Annual Meeting the American Association of Immunol- ogists
    • Place of Presentation
      Hynes Convention Center(USA)
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Presentation] Tissue matricellular protei- ns regulate effector Tcells from dr- aining lymph nodes via alpah9 integ- rin-signaling2012

    • Author(s)
      Uede T
    • Organizer
      FASEB summer research conference Osteopontin Biology
    • Place of Presentation
      Vermont Academy(USA)
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Presentation] 細胞外マトリックスが創り出す関節リウマチ病巣及び局所リンパ節微小環境。2012

    • Author(s)
      上出利光
    • Organizer
      第101回日本病理学会
    • Place of Presentation
      京王プラザホテル(東京)
    • Invited
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Presentation] The role of matricellular proteins and their integrin receptors in generation of tumortissue microenvironments.2012

    • Author(s)
      Toshimitsu Uede
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌(札幌)
    • Invited
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Presentation] The role of matricellular p- roteins and their integrin receptors in generation of tumor tissue micr-oenvironments2012

    • Author(s)
      Uede T
    • Organizer
      第71回日本癌学会学術総会モーニングレクチャー
    • Place of Presentation
      札幌市教育文化会館(札幌)
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Presentation] Alpha9 beta1 integrin, as a critical regulator of lymphat-ic metastasis and growth of human b- reast cancer cells2011

    • Author(s)
      Ohta D, Uede T
    • Organizer
      American Associ- ation for Cancer Research 102nd Annu- al Meeting 2011
    • Place of Presentation
      Orange County Convention Center(USA)
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Presentation] Interaction of alpha9 integrin on medullary sin-us with its ligand regulates lympho- cyte egress via regulating S1P tran- sporter, Spns2 expression and subse- quent S1P secretion under inflammat- ory condition2011

    • Author(s)
      Ito K, Matsui Y, Kurotaki D, Morimo- to J, Kihara A, Uede T
    • Organizer
      98th Annual Meeting the American Association of Immunol- ogists
    • Place of Presentation
      Moscone Center (USA)
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Presentation] Alpha9 beta1 integ- rin-mediated signaling serves as an intrinsic regulator of pathogenic Th17 cell generation2011

    • Author(s)
      Kanayama M, Morimoto J, Matsui Y, Y- oshida T, Uede T
    • Organizer
      98th Annual Meet-ing the American Association of Imm- unologists
    • Place of Presentation
      Moscone C- enter(USA)
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Presentation] A specific antibody against thrombin-cleaved osteopontin contributes to inhibition of renal crystal formation in mice2011

    • Author(s)
      Hamamoto Syuzo, Yasui Takahiro, Okada Atsushi, Matsui Yutaka, Kon Shigeyuki, Sakai Fumihiko, Tozawa Keiichi, Uede Toshimitsu, Kohri Kenjiro
    • Organizer
      第10回オステオポンチン研究会
    • Place of Presentation
      北海道大学(札幌市)
    • Data Source
      KAKENHI-PROJECT-23249074
  • [Presentation] オステオポンチン中和抗体を用いた腎結石形成のメカニズムの解明と分子標的治療への応用2011

    • Author(s)
      濱本周造、安井孝周、岡田淳志、田口和己、小島祥敬、戸澤啓一、佐々木昌一、上出利光、郡健二郎
    • Organizer
      第99回日本泌尿器科学会総会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Data Source
      KAKENHI-PROJECT-23249074
  • [Presentation] Crucial role of the cryptic epitope SLAYGLR within osteopontin in renal crystal formation of mice2011

    • Author(s)
      Hamamoto Shuzo, Yasui Takahiro, Okada Atsushi, Niimi Kazuhiro, Fujii Yasuhiro, Taguchi Kazumi, Tozawa Keiichi, Uede Toshimitsu, Kohri Kenjiro
    • Organizer
      1st Meeting of the EAU Section of Urolithiasis (EULIS)
    • Place of Presentation
      The Mermaid Conference & Events Center(イギリス)
    • Data Source
      KAKENHI-PROJECT-23249074
  • [Presentation] Matricellular proteins as intrinsic regulators of tumor invasion and metastasis in tumor tissue microenvironments2011

    • Author(s)
      上出利光
    • Organizer
      平成23年度遺伝子病制御研究所共同研究集会
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2011-09-06
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Presentation] 組織微小環境の内的調節因子、オステオポンチンの病態病理学2010

    • Author(s)
      上出利光
    • Organizer
      第99回日本病理学会総会宿題報告
    • Place of Presentation
      京王プラザホテル(東京都)(招待講演)
    • Data Source
      KAKENHI-PUBLICLY-22021003
  • [Presentation] 組織微小環境の内的調節因子、オステオポンチンの病態病理学2010

    • Author(s)
      上出利光
    • Organizer
      第99回日本病理学会総会宿題報告
    • Place of Presentation
      京王プラザホテル(東京都) 招待講演
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Presentation] Osteopontin, a key intrinsic regulator of various intractable inflammatory disorders.2010

    • Author(s)
      上出利光
    • Organizer
      浙江大学講演会
    • Place of Presentation
      浙江大学(杭州市・中国) 招待講演
    • Year and Date
      2010-06-14
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Presentation] The aberrant interaction of matricellular proteins and integrins in pathological foci leads to inflammatory tissue damage.2010

    • Author(s)
      上出利光
    • Organizer
      FASEB summer research conferences
    • Place of Presentation
      The Steamboat Grand Resort(スティームボート・USA) 招待講演
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Presentation] Matricellular proteins and their integrin receptors-new drug targets for inflammatory disorders and cancers2010

    • Author(s)
      上出利光
    • Organizer
      Novo Nordisk Symposium
    • Place of Presentation
      Nova Nordisk(北京市・中国)(招待講演)
    • Year and Date
      2010-11-04
    • Data Source
      KAKENHI-PUBLICLY-22021003
  • [Presentation] 組織微小環境の内的調節因子、オステオポンチンの病態病理学2010

    • Author(s)
      上出利光
    • Organizer
      第99回日本病理学会総会宿題報告
    • Place of Presentation
      京王プラザホテル(東京)
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Presentation] Matricellular proteins and their integrin receptors-new drug targets for inflammatory disorders and cancers2010

    • Author(s)
      上出利光
    • Organizer
      Novo Nordisk Symposium
    • Place of Presentation
      Novo Nordisk(北京市・中国) 招待講演
    • Year and Date
      2010-11-04
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Presentation] The aberrant interaction of matricellular proteins and integrins in pathological foci leads to inflammatory tissue damage.2010

    • Author(s)
      上出利光
    • Organizer
      FASEB summer research conferences
    • Place of Presentation
      The Steamboat Grand Resort(スティームボート・USA)(招待講演)
    • Data Source
      KAKENHI-PUBLICLY-22021003
  • [Presentation] Osteopontin, a key intrinsic regulator of various intractable inflammatory disorders.2010

    • Author(s)
      上出利光
    • Organizer
      浙江大学講演会
    • Place of Presentation
      浙江大学(杭州市・中国)(招待講演)
    • Year and Date
      2010-06-14
    • Data Source
      KAKENHI-PUBLICLY-22021003
  • [Presentation] The aberrant interaction of matricellular proteins and integrins in pathological foci leads to infl- ammatory tissue damage2010

    • Author(s)
      Uede T
    • Organizer
      Invited spe- aker, FASEB summer research confere- nces
    • Place of Presentation
      The Steamboat Gra- nd Resort(USA)
    • Data Source
      KAKENHI-PROJECT-21390113
  • [Presentation] Alpha9 integrin and its ligands con- stitute critical joint microenviron- ments for development of autoimmunearthritis2009

    • Author(s)
      Kanayama M, Kurotaki D, Morimoto J, Asano T, Matsui Y, Nakayama Y, Saito Y, Ito K, Kimura C, Iwasaki N, Suz- uki K, Harada T, Li HM, Uehara J, M- iyazaki T, Minami A, Kon S, Uede T
    • Organizer
      第39回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Data Source
      KAKENHI-PROJECT-21390113
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  • 120.  大塚 榮子 (80028836)
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  • 121.  SUDO Tetsuo
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  • 122.  MAEDA Masahiro
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  • 124.  須藤 哲夫
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  • 126.  ISHIT Yoshifumi
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  • 128.  吉田 利通
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  • 129.  尾松 芳樹
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  • 130.  石津 綾子
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