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YACHI Akira  谷内 昭

ORCIDConnect your ORCID iD *help
Researcher Number 50045324
Affiliation (based on the past Project Information) *help 1993: 札幌医科大学, 医学部, 学長
1988 – 1993: 札幌医科大学, 教授
1986 – 1992: 札幌医科大学, 医学部, 教授
1990 – 1991: 札幌医大, 医学部, 教授
1986: Sapporo Medical College, Department of Medicine, 医学部, 教授
1985: 札幌医科大学, 医, 教授
Review Section/Research Field
Principal Investigator
Gastroenterology / 内科学一般
Except Principal Investigator
Gastroenterology / 内科学一般
Keywords
Principal Investigator
CEA / モノクローナル抗体 / NCA / ICAM-1 / セレクチンファミリー / 糖鎖構造 / 高感度微量測定法 / ヘリコバクタ・ピロリ菌 / 慢性胃炎 / モノクロ-ナル抗体 … More / Campylobacter pylori / 自己抗体 / CEA遺伝子 / BGP1 / AFP / ras / 分子生物学 / BGPI / CEAファミリ-遺伝子 / トランスフェクト-マ / 消化器癌マ-カ- / トランスジェニックマウス / BGP / 細胞間接着分子 / DCC / CEAファミリー / チロシン脱リン酸化酵素 / E-カドヘリン / CD23 / 硫酸化糖鎖 / チロシンホスファターゼ / クローニング / 遺伝子クローニング / 消化器系癌抗原 / 癌遺伝子 / 癌胎児性蛋白 / 分子生物学的研究 / 消化器癌関連抗原 / Carcinoembryonic antigen / 分子生物学的解析 / カンピロバクタ・ピロリ菌 / 局所免疫応答 / 胃潰瘍 / 十二指腸潰瘍 / 組織学的重症度 / Helicobacter pylori / Chronic Gastritis / Monoclinal antibody / Local immune response / ヘリコバタタ・ピロリ菌 / 病態解析 / 胃液 / SIgA / SIgA抗体 / H. pylori / Chronic gastritis / Analysis of the Disease / Gastric juice / sIgA / 自己抗原 / ヒト型モノクローナル抗体 / エピトープ / Autoantibody / Autoantigen / Human monoclonal antibody / 抗イディオタイプ抗体 / anti-idiotypic antibody / Monoclonal antibody / autoimmune disease … More
Except Principal Investigator
CEA / モノクローナル抗体 / モノクロナル抗体 / 抗イディオタイプ抗体 / 腫瘍マーカー / 放射免疫局在診断 / AFP / 腫瘍マ-カ- / 大腸癌 / モノクロ-ナル抗体 / 癌胎児性抗原 / 腫瘍免疫 / 免疫療法 / イディオタイプ・ネットワ-ク / 抗原・内部イメ-ジ / ワクチン効果 / 肝癌 / GPI-アンカー / RT-PCR法 / アミロイド-シス / Amyloidosis / Monoclonal antibody / Alzheimer's disease / ICAM-1 / αーフェトプロテイン / Biliary glycoprotein I / Nonspecific crossreacting antigen / in situ hybridization / transfectoma / 抗合成ペプチドモノクローナル抗体 / イディオタイプネットワーク / 抗原のインターナルイメージ / DNAクロ-ニング / アルファフエトプロテイン / GSTーP / MnーSOD / GPI結合型蛋白質 / NCA / BGP / 細胞接着活性 / GST-P / キメラ抗体 / 癌抗原 / 抗体複合体 / Mn-SOD / carcinoembryonic antigen(CEA) / 癌特異性 / 正常大腸粘膜 / Carcinoembryonic antigen / Adhesion molecule / Collagen gel / Differentiation / 膵炎 / 早期診断 / PCR / MUSE11 / 膵癌 / 腫瘍細胞 / ムチン抗原遺伝子 / 胃潰瘍 / 再生上皮 / NCAM / H^+,K^+-ATPase / gastric ulcer / neural cell adhesion molecule / regeneration / 大腸粘膜crypt / ヘリコバクタ・ピロリ / 胃がん / 腸上皮化生 / TPR-MET再構成 / 癌細胞増殖抑制 / 新しい治療法 / 前癌病変マーカー / 癌遺伝子 / DNAプローブ / 糖鎖の癌性変化 / ミサイル療法 / 腺癌関連抗原 / アモロイド関連蛋白 / アルツハイマ-病 / β蛋白 / アミロイド関連蛋白 / アミロイド / 続発性アミロイド-シス / β-蛋白 / Amyloid associated protein / beta-protein / 接着分子 / 血中遊離抗原 / 殺細胞機序 / 癌の転移・臓器浸潤 / ICAMー1 / adhesion modecule / circulating antigen / cytotoxic mechanism / metastasis and invasion of cancer cells / アミロイドーシス / アミロイド関連蛋白遺伝子 / アルツハイマー病 / AA蛋白 / 新アミロイド関連蛋白 / アミロイド蛋白 / AM34抗原遺伝子 / Amyloid-related protein gene / AA protein / New amyloid-related protein / 血中放出機序 / 膜抗原 / tight junction / tight junciton / インタ-フェロン / 動物モデル / Mechanisms of shedding / Membrane antigen / Fight junction / 胆汁うっ滞 / 細胞骨格 / チロシン脱リン酸化酵素 / PTPH1遺伝子 / PTPH1 / c-myc / 染色体9番長腕31領域 / Bile stasis / Cytoskeletal protein / Protein tyrosine phosphatase / PTPH1 gene Less
  • Research Projects

    (37 results)
  • Co-Researchers

    (32 People)
  •  消化器癌における細胞接着分子の遺伝子および機能解析と診断応用Principal Investigator

    • Principal Investigator
      谷内 昭
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  CEAの癌特異性の解明:大腸粘膜におけるその産生動態の生理と病理

    • Principal Investigator
      松岡 雄治
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Fukuoka University
  •  腸上皮化生・胃がんへの進展におけるヘリコバクタ感染とTPR-MET再構成の関連

    • Principal Investigator
      杉山 敏郎
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  Molecular biological analysis of cytoskeletal associated protein in bile stasis.

    • Principal Investigator
      TANDA Mariko
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University, School of Medicine
  •  腫瘍マーカーの基礎的臨床的研究

    • Principal Investigator
      西 信三
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hokkaido University
  •  消化器癌における細胞接着分子の遺伝子及び機能解析と診断応用Principal Investigator

    • Principal Investigator
      谷内 昭
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  CEAの癌特異性の解明:大腸粘膜におけるその産生動態の生理と病理

    • Principal Investigator
      松岡 雄治
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Fukuoka University
  •  細胞間接着分子CEAおよびBGPの大腸腺管形成における役割と癌化に伴う異常

    • Principal Investigator
      杉山 敏郎
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  膵癌の高危険群選別を目的とした超微量腫瘍細胞の特異的検出系の開発

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  胃潰瘍再生上皮における細胞間接着分子発現とH^+,K^+-ATPaseの関連

    • Principal Investigator
      杉山 敏郎
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  腫瘍マ-カ-の基礎的臨床的研究

    • Principal Investigator
      西 信三
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hokkaido University
  •  CEAの癌特異性の解明:大腸粘膜におけるその産生動態の生理と病理

    • Principal Investigator
      松岡 雄治
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Fukuoka University
  •  消化器癌腫瘍マ-カ-分子のtransgenicマウスを用いた機能解析Principal Investigator

    • Principal Investigator
      谷内 昭
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  イディオタイプ・ネットワ-クを応用した免疫療法の基礎

    • Principal Investigator
      辻崎 正幸
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  Association of H. pylori with immunological aspects of chronic gastritisPrincipal Investigator

    • Principal Investigator
      YACHI Akira
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical College
  •  The analysis of immune response and cytotoxic mechanism with use of anti-ICAM-1 monoclonal antibodies

    • Principal Investigator
      TSUJISAKI Masayuki
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Sapporo Medical College
  •  Analysis of amyloidosis by novel amyloid-related protein gene.

    • Principal Investigator
      IAMI Kohzoh
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Sapporo Medical College
  •  Study on the mechanisms of shedding of CEA into the serum by experimental system

    • Principal Investigator
      HOSHI Hideki
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical College
  •  腫瘍マ-カ-およびその遺伝子の構造解析ならびに臨床応用

    • Principal Investigator
      西 信三
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hokkaido University
  •  CEA遺伝子ファミリ-の機能ならびに発現調節機構の解析Principal Investigator

    • Principal Investigator
      谷内 昭
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  イディオタイプ・ネットワ-クを応用した免疫療法の基礎

    • Principal Investigator
      辻崎 正幸
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  腫瘍マーカーおよびその遺伝子の構造解析ならびに臨床応用

    • Principal Investigator
      西 信三
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hokkaido University
  •  消化器系抗原とその遺伝子に関する免疫学的・分子生物学的研究ならびに新しい応用Principal Investigator

    • Principal Investigator
      谷内 昭
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  CEA関連抗原遺伝子の分子生物学的解析および産物の機能

    • Principal Investigator
      HINODA Yuji
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  抗イディオタイプ・モノクローナル抗体を用いた新しい癌の免疫療法の基礎

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  Effect of Campylobacter Pylori upon Immunological Conditions of Chronic Gastritis.Principal Investigator

    • Principal Investigator
      YACHI Akira
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical College
  •  Detection of Novel Amyloid-Associated Protein by Monoclonal Antibody and its Gene Analysis

    • Principal Investigator
      IMAI Kohzoh
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Sapporo Medical College
  •  腫瘍マーカーおよびその遺伝子の構造解析ならびに臨床応用

    • Principal Investigator
      西 信三
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hokkaido University
  •  消化器系癌抗原とその遺伝子に関する免疫学的・分子生物学的研究なよびに新しい応用Principal Investigator

    • Principal Investigator
      谷内 昭
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  抗イディオタイプならびに改造分子モノクローナル抗体を用いた癌の新しい診断の基礎

    • Principal Investigator
      日野田 裕治
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  消化器系癌抗原とその遺伝子に関する免疫学的・分子生物学的研究ならびに新しい応用Principal Investigator

    • Principal Investigator
      谷内 昭
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  分子生物学的・免疫学的方法を用いた肝および大腸前癌マーカーの解析と新しい診断法

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  Analysis of the auto-antibody in the serum from patients by use of anti-idiotypic monoclonal antibodies.Principal Investigator

    • Principal Investigator
      YACHI Akira
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      Sapporo Medical College
  •  ヒト癌細胞増殖抑制に働くモノクローナル抗体を応用した新しい癌の治療法に関する研究

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  モノクローナル抗体を用いたCEAの免疫学的・分子生物学的研究ならびに新しい応用Principal Investigator

    • Principal Investigator
      谷内 昭
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  Preparation of human monoclonal antibodies using human B cell producing autoantibodies and analyses of novel autoantigens.Principal Investigator

    • Principal Investigator
      YACHI Akira
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      Sapporo Medical College
  •  モノクローナル抗体を用いたCEAの免疫学的・分子生物学的研究ならびに新しい応用Principal Investigator

    • Principal Investigator
      谷内 昭
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  • 1.  IMAI Kohzoh (60117603)
    # of Collaborated Projects: 21 results
    # of Collaborated Products: 0 results
  • 2.  HINODA Yuji (10165128)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 0 results
  • 3.  西 信三 (20001894)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 4.  SUGIYAMA Toshiro (00196768)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 5.  松岡 雄治 (70078773)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 6.  森 武貞 (60028496)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 7.  TSUJISAKI Masayuki (50217311)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 8.  高橋 俊雄 (50079828)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 9.  小路 敏彦 (20039811)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 10.  YABANA Tsuyoshi (70045491)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  遠藤 康夫 (60010302)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  平井 秀松 (30000889)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  葛巻 暹 (80091445)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 14.  山下 克子 (70030905)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 15.  池原 征夫 (70037612)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 16.  村田 長芳 (60020765)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 17.  宮木 美知子 (20085624)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  ITOH Fumio (90223180)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  ENDO Takao (40191928)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 20.  武田 和久 (50033080)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 21.  谷口 直之 (90002188)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 22.  名倉 宏 (90022821)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 23.  神奈木 玲児 (80161389)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 24.  及川 信三
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 25.  HOSHI Hideki (90219163)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  TANDA Mariko (40240931)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  酒井 正春 (50162269)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  上出 利光 (00160185)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  藤井 暢弘 (90133719)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  木幡 陽 (30030852)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  加藤 康夫 (90185877)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  中里 紘
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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