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YACHI Akira
谷内 昭
Connect your ORCID iD
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Researcher Number
50045324
Affiliation (based on the past Project Information)
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1993: 札幌医科大学, 医学部, 学長
1988 – 1993: 札幌医科大学, 教授
1986 – 1992: 札幌医科大学, 医学部, 教授
1990 – 1991: 札幌医大, 医学部, 教授
1986: Sapporo Medical College, Department of Medicine, 医学部, 教授
1985: 札幌医科大学, 医, 教授
Review Section/Research Field
Principal Investigator
Gastroenterology
/
内科学一般
Except Principal Investigator
Gastroenterology
/
内科学一般
Keywords
Principal Investigator
CEA / モノクローナル抗体 / NCA / ICAM-1 / セレクチンファミリー / 糖鎖構造 / 高感度微量測定法 / ヘリコバクタ・ピロリ菌 / 慢性胃炎 / モノクロ-ナル抗体
…
More
/ Campylobacter pylori / 自己抗体 / CEA遺伝子 / BGP1 / AFP / ras / 分子生物学 / BGPI / CEAファミリ-遺伝子 / トランスフェクト-マ / 消化器癌マ-カ- / トランスジェニックマウス / BGP / 細胞間接着分子 / DCC / CEAファミリー / チロシン脱リン酸化酵素 / E-カドヘリン / CD23 / 硫酸化糖鎖 / チロシンホスファターゼ / クローニング / 遺伝子クローニング / 消化器系癌抗原 / 癌遺伝子 / 癌胎児性蛋白 / 分子生物学的研究 / 消化器癌関連抗原 / Carcinoembryonic antigen / 分子生物学的解析 / カンピロバクタ・ピロリ菌 / 局所免疫応答 / 胃潰瘍 / 十二指腸潰瘍 / 組織学的重症度 / Helicobacter pylori / Chronic Gastritis / Monoclinal antibody / Local immune response / ヘリコバタタ・ピロリ菌 / 病態解析 / 胃液 / SIgA / SIgA抗体 / H. pylori / Chronic gastritis / Analysis of the Disease / Gastric juice / sIgA / 自己抗原 / ヒト型モノクローナル抗体 / エピトープ / Autoantibody / Autoantigen / Human monoclonal antibody / 抗イディオタイプ抗体 / anti-idiotypic antibody / Monoclonal antibody / autoimmune disease
…
More
Except Principal Investigator
CEA / モノクローナル抗体 / モノクロナル抗体 / 抗イディオタイプ抗体 / 腫瘍マーカー / 放射免疫局在診断 / AFP / 腫瘍マ-カ- / 大腸癌 / モノクロ-ナル抗体 / 癌胎児性抗原 / 腫瘍免疫 / 免疫療法 / イディオタイプ・ネットワ-ク / 抗原・内部イメ-ジ / ワクチン効果 / 肝癌 / GPI-アンカー / RT-PCR法 / アミロイド-シス / Amyloidosis / Monoclonal antibody / Alzheimer's disease / ICAM-1 / αーフェトプロテイン / Biliary glycoprotein I / Nonspecific crossreacting antigen / in situ hybridization / transfectoma / 抗合成ペプチドモノクローナル抗体 / イディオタイプネットワーク / 抗原のインターナルイメージ / DNAクロ-ニング / アルファフエトプロテイン / GSTーP / MnーSOD / GPI結合型蛋白質 / NCA / BGP / 細胞接着活性 / GST-P / キメラ抗体 / 癌抗原 / 抗体複合体 / Mn-SOD / carcinoembryonic antigen(CEA) / 癌特異性 / 正常大腸粘膜 / Carcinoembryonic antigen / Adhesion molecule / Collagen gel / Differentiation / 膵炎 / 早期診断 / PCR / MUSE11 / 膵癌 / 腫瘍細胞 / ムチン抗原遺伝子 / 胃潰瘍 / 再生上皮 / NCAM / H^+,K^+-ATPase / gastric ulcer / neural cell adhesion molecule / regeneration / 大腸粘膜crypt / ヘリコバクタ・ピロリ / 胃がん / 腸上皮化生 / TPR-MET再構成 / 癌細胞増殖抑制 / 新しい治療法 / 前癌病変マーカー / 癌遺伝子 / DNAプローブ / 糖鎖の癌性変化 / ミサイル療法 / 腺癌関連抗原 / アモロイド関連蛋白 / アルツハイマ-病 / β蛋白 / アミロイド関連蛋白 / アミロイド / 続発性アミロイド-シス / β-蛋白 / Amyloid associated protein / beta-protein / 接着分子 / 血中遊離抗原 / 殺細胞機序 / 癌の転移・臓器浸潤 / ICAMー1 / adhesion modecule / circulating antigen / cytotoxic mechanism / metastasis and invasion of cancer cells / アミロイドーシス / アミロイド関連蛋白遺伝子 / アルツハイマー病 / AA蛋白 / 新アミロイド関連蛋白 / アミロイド蛋白 / AM34抗原遺伝子 / Amyloid-related protein gene / AA protein / New amyloid-related protein / 血中放出機序 / 膜抗原 / tight junction / tight junciton / インタ-フェロン / 動物モデル / Mechanisms of shedding / Membrane antigen / Fight junction / 胆汁うっ滞 / 細胞骨格 / チロシン脱リン酸化酵素 / PTPH1遺伝子 / PTPH1 / c-myc / 染色体9番長腕31領域 / Bile stasis / Cytoskeletal protein / Protein tyrosine phosphatase / PTPH1 gene
Less
Research Projects
(
37
results)
Co-Researchers
(
32
People)
Project Start Year (Newest)
Project Start Year (Oldest)
消化器癌における細胞接着分子の遺伝子および機能解析と診断応用
Principal Investigator
Principal Investigator
谷内 昭
Project Period (FY)
1993
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
CEAの癌特異性の解明:大腸粘膜におけるその産生動態の生理と病理
Principal Investigator
松岡 雄治
Project Period (FY)
1993
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Fukuoka University
腸上皮化生・胃がんへの進展におけるヘリコバクタ感染とTPR-MET再構成の関連
Principal Investigator
杉山 敏郎
Project Period (FY)
1993
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
Molecular biological analysis of cytoskeletal associated protein in bile stasis.
Principal Investigator
TANDA Mariko
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Gastroenterology
Research Institution
Sapporo Medical University, School of Medicine
腫瘍マーカーの基礎的臨床的研究
Principal Investigator
西 信三
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hokkaido University
消化器癌における細胞接着分子の遺伝子及び機能解析と診断応用
Principal Investigator
Principal Investigator
谷内 昭
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
CEAの癌特異性の解明:大腸粘膜におけるその産生動態の生理と病理
Principal Investigator
松岡 雄治
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Fukuoka University
細胞間接着分子CEAおよびBGPの大腸腺管形成における役割と癌化に伴う異常
Principal Investigator
杉山 敏郎
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
膵癌の高危険群選別を目的とした超微量腫瘍細胞の特異的検出系の開発
Principal Investigator
今井 浩三
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
Gastroenterology
Research Institution
Sapporo Medical University
胃潰瘍再生上皮における細胞間接着分子発現とH^+,K^+-ATPaseの関連
Principal Investigator
杉山 敏郎
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Gastroenterology
Research Institution
Sapporo Medical University
腫瘍マ-カ-の基礎的臨床的研究
Principal Investigator
西 信三
Project Period (FY)
1991
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hokkaido University
CEAの癌特異性の解明:大腸粘膜におけるその産生動態の生理と病理
Principal Investigator
松岡 雄治
Project Period (FY)
1991
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Fukuoka University
消化器癌腫瘍マ-カ-分子のtransgenicマウスを用いた機能解析
Principal Investigator
Principal Investigator
谷内 昭
Project Period (FY)
1991
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
イディオタイプ・ネットワ-クを応用した免疫療法の基礎
Principal Investigator
辻崎 正幸
Project Period (FY)
1991
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
Association of H. pylori with immunological aspects of chronic gastritis
Principal Investigator
Principal Investigator
YACHI Akira
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Gastroenterology
Research Institution
Sapporo Medical College
The analysis of immune response and cytotoxic mechanism with use of anti-ICAM-1 monoclonal antibodies
Principal Investigator
TSUJISAKI Masayuki
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
内科学一般
Research Institution
Sapporo Medical College
Analysis of amyloidosis by novel amyloid-related protein gene.
Principal Investigator
IAMI Kohzoh
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
内科学一般
Research Institution
Sapporo Medical College
Study on the mechanisms of shedding of CEA into the serum by experimental system
Principal Investigator
HOSHI Hideki
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Gastroenterology
Research Institution
Sapporo Medical College
腫瘍マ-カ-およびその遺伝子の構造解析ならびに臨床応用
Principal Investigator
西 信三
Project Period (FY)
1990
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hokkaido University
CEA遺伝子ファミリ-の機能ならびに発現調節機構の解析
Principal Investigator
Principal Investigator
谷内 昭
Project Period (FY)
1990
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
イディオタイプ・ネットワ-クを応用した免疫療法の基礎
Principal Investigator
辻崎 正幸
Project Period (FY)
1990
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
腫瘍マーカーおよびその遺伝子の構造解析ならびに臨床応用
Principal Investigator
西 信三
Project Period (FY)
1989
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hokkaido University
消化器系抗原とその遺伝子に関する免疫学的・分子生物学的研究ならびに新しい応用
Principal Investigator
Principal Investigator
谷内 昭
Project Period (FY)
1989
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
CEA関連抗原遺伝子の分子生物学的解析および産物の機能
Principal Investigator
HINODA Yuji
Project Period (FY)
1989
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
抗イディオタイプ・モノクローナル抗体を用いた新しい癌の免疫療法の基礎
Principal Investigator
今井 浩三
Project Period (FY)
1989
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
Effect of Campylobacter Pylori upon Immunological Conditions of Chronic Gastritis.
Principal Investigator
Principal Investigator
YACHI Akira
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Gastroenterology
Research Institution
Sapporo Medical College
Detection of Novel Amyloid-Associated Protein by Monoclonal Antibody and its Gene Analysis
Principal Investigator
IMAI Kohzoh
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
内科学一般
Research Institution
Sapporo Medical College
腫瘍マーカーおよびその遺伝子の構造解析ならびに臨床応用
Principal Investigator
西 信三
Project Period (FY)
1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hokkaido University
消化器系癌抗原とその遺伝子に関する免疫学的・分子生物学的研究なよびに新しい応用
Principal Investigator
Principal Investigator
谷内 昭
Project Period (FY)
1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
抗イディオタイプならびに改造分子モノクローナル抗体を用いた癌の新しい診断の基礎
Principal Investigator
日野田 裕治
Project Period (FY)
1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
消化器系癌抗原とその遺伝子に関する免疫学的・分子生物学的研究ならびに新しい応用
Principal Investigator
Principal Investigator
谷内 昭
Project Period (FY)
1987
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
分子生物学的・免疫学的方法を用いた肝および大腸前癌マーカーの解析と新しい診断法
Principal Investigator
今井 浩三
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
Analysis of the auto-antibody in the serum from patients by use of anti-idiotypic monoclonal antibodies.
Principal Investigator
Principal Investigator
YACHI Akira
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
内科学一般
Research Institution
Sapporo Medical College
ヒト癌細胞増殖抑制に働くモノクローナル抗体を応用した新しい癌の治療法に関する研究
Principal Investigator
今井 浩三
Project Period (FY)
1986
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
モノクローナル抗体を用いたCEAの免疫学的・分子生物学的研究ならびに新しい応用
Principal Investigator
Principal Investigator
谷内 昭
Project Period (FY)
1985
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
Preparation of human monoclonal antibodies using human B cell producing autoantibodies and analyses of novel autoantigens.
Principal Investigator
Principal Investigator
YACHI Akira
Project Period (FY)
1985 – 1986
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
内科学一般
Research Institution
Sapporo Medical College
モノクローナル抗体を用いたCEAの免疫学的・分子生物学的研究ならびに新しい応用
Principal Investigator
Principal Investigator
谷内 昭
Project Period (FY)
1984 – 1986
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
# of Projects (Dsc)
# of Projects (Asc)
1.
IMAI Kohzoh
(60117603)
# of Collaborated Projects:
21 results
# of Collaborated Products:
0 results
2.
HINODA Yuji
(10165128)
# of Collaborated Projects:
13 results
# of Collaborated Products:
0 results
3.
西 信三
(20001894)
# of Collaborated Projects:
9 results
# of Collaborated Products:
0 results
4.
SUGIYAMA Toshiro
(00196768)
# of Collaborated Projects:
8 results
# of Collaborated Products:
0 results
5.
松岡 雄治
(70078773)
# of Collaborated Projects:
8 results
# of Collaborated Products:
0 results
6.
森 武貞
(60028496)
# of Collaborated Projects:
7 results
# of Collaborated Products:
0 results
7.
TSUJISAKI Masayuki
(50217311)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
8.
高橋 俊雄
(50079828)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
9.
小路 敏彦
(20039811)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
10.
YABANA Tsuyoshi
(70045491)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
11.
遠藤 康夫
(60010302)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
12.
平井 秀松
(30000889)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
13.
葛巻 暹
(80091445)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
14.
山下 克子
(70030905)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
15.
池原 征夫
(70037612)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
16.
村田 長芳
(60020765)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
17.
宮木 美知子
(20085624)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
18.
ITOH Fumio
(90223180)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
19.
ENDO Takao
(40191928)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
20.
武田 和久
(50033080)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
21.
谷口 直之
(90002188)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
22.
名倉 宏
(90022821)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
23.
神奈木 玲児
(80161389)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
24.
及川 信三
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
25.
HOSHI Hideki
(90219163)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
TANDA Mariko
(40240931)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
酒井 正春
(50162269)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
28.
上出 利光
(00160185)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
29.
藤井 暢弘
(90133719)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
30.
木幡 陽
(30030852)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
31.
加藤 康夫
(90185877)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
32.
中里 紘
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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