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YACHI Akira
谷内 昭
Connect your ORCID iD
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Researcher Number
50045324
Affiliation (based on the past Project Information)
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1993 : 札幌医科大学, 医学部, 学長
1988 – 1993 : 札幌医科大学, 教授
1986 – 1992 : 札幌医科大学, 医学部, 教授
1990 – 1991 : 札幌医大, 医学部, 教授
1986 : Sapporo Medical College, Department of Medicine, 医学部, 教授
1985 : 札幌医科大学, 医, 教授
Review Section/Research Field
Except Principal Investigator
Gastroenterology
/
内科学一般
Keywords
Except Principal Investigator
CEA / モノクローナル抗体 / 抗イディオタイプ抗体 / モノクロ-ナル抗体 / モノクロナル抗体 / AFP / ICAM-1 / 腫瘍マ-カ- / 腫瘍マーカー / Monoclonal antibody
…
More
/ 大腸癌 / 放射免疫局在診断 / NCA / 糖鎖構造 / BGP / ワクチン効果 / ヘリコバクタ・ピロリ菌 / Carcinoembryonic antigen / RT-PCR法 / 腫瘍免疫 / Alzheimer's disease / 癌遺伝子 / チロシン脱リン酸化酵素 / 肝癌 / イディオタイプ・ネットワ-ク / 胃潰瘍 / 抗原・内部イメ-ジ / セレクチンファミリー / 慢性胃炎 / 自己抗体 / 免疫療法 / 高感度微量測定法 / Campylobacter pylori / GPI-アンカー / Amyloidosis / アミロイド-シス / 癌胎児性抗原 / Autoantigen / Monoclinal antibody / New amyloid-related protein / 再生上皮 / 膜抗原 / Biliary glycoprotein I / anti-idiotypic antibody / AA蛋白 / アルファフエトプロテイン / SIgA / 消化器癌マ-カ- / metastasis and invasion of cancer cells / NCAM / β蛋白 / ムチン抗原遺伝子 / DCC / 硫酸化糖鎖 / アミロイドーシス / Human monoclonal antibody / トランスジェニックマウス / 胃液 / アルツハイマー病 / キメラ抗体 / CD23 / H. pylori / 血中放出機序 / Mn-SOD / アルツハイマ-病 / 新しい治療法 / 腫瘍細胞 / 早期診断 / GPI結合型蛋白質 / Membrane antigen / 細胞間接着分子 / 続発性アミロイド-シス / ヘリコバクタ・ピロリ / Amyloid associated protein / 癌抗原 / PCR / 大腸粘膜crypt / 分子生物学的解析 / 動物モデル / Analysis of the Disease / GST-P / 消化器系癌抗原 / cytotoxic mechanism / neural cell adhesion molecule / 腸上皮化生 / 染色体9番長腕31領域 / BGPI / MnーSOD / 分子生物学的研究 / 胃がん / CEAファミリー / ヘリコバタタ・ピロリ菌 / BGP1 / Chronic Gastritis / 血中遊離抗原 / Protein tyrosine phosphatase / 癌胎児性蛋白 / Gastric juice / Cytoskeletal protein / アミロイド関連蛋白遺伝子 / Chronic gastritis / インタ-フェロン / CEAファミリ-遺伝子 / circulating antigen / Differentiation / Adhesion molecule / 胆汁うっ滞 / beta-protein / 分子生物学 / 抗原のインターナルイメージ / regeneration / トランスフェクト-マ / 細胞接着活性 / 病態解析 / 遺伝子クローニング / AM34抗原遺伝子 / 消化器癌関連抗原 / DNAプローブ / gastric ulcer / Nonspecific crossreacting antigen / adhesion modecule / Fight junction / 接着分子 / 癌の転移・臓器浸潤 / ヒト型モノクローナル抗体 / 自己抗原 / sIgA / transfectoma / 抗体複合体 / carcinoembryonic antigen(CEA) / AA protein / ICAMー1 / 膵炎 / β-蛋白 / 新アミロイド関連蛋白 / SIgA抗体 / PTPH1遺伝子 / イディオタイプネットワーク / 正常大腸粘膜 / アミロイド / Amyloid-related protein gene / Local immune response / c-myc / チロシンホスファターゼ / tight junciton / カンピロバクタ・ピロリ菌 / Bile stasis / 抗合成ペプチドモノクローナル抗体 / クローニング / PTPH1 / 膵癌 / Collagen gel / ras / Helicobacter pylori / エピトープ / GSTーP / アミロイド蛋白 / autoimmune disease / 癌細胞増殖抑制 / ミサイル療法 / CEA遺伝子 / 殺細胞機序 / tight junction / 組織学的重症度 / 局所免疫応答 / TPR-MET再構成 / アミロイド関連蛋白 / Autoantibody / PTPH1 gene / 癌特異性 / 腺癌関連抗原 / E-カドヘリン / αーフェトプロテイン / 前癌病変マーカー / 糖鎖の癌性変化 / DNAクロ-ニング / アモロイド関連蛋白 / 十二指腸潰瘍 / in situ hybridization / Mechanisms of shedding / H^+,K^+-ATPase / MUSE11 / 細胞骨格
Less
Research Projects
(
37
results)
Co-Researchers
(
32
People)
Project Start Year(Newest)
Project Start Year(Oldest)
消化器癌における細胞接着分子の遺伝子および機能解析と診断応用
Principal Investigator
Principal Investigator
谷内 昭
Project Period (FY)
1993
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
CEAの癌特異性の解明:大腸粘膜におけるその産生動態の生理と病理
Principal Investigator
松岡 雄治
Project Period (FY)
1993
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Fukuoka University
腸上皮化生・胃がんへの進展におけるヘリコバクタ感染とTPR-MET再構成の関連
Principal Investigator
杉山 敏郎
Project Period (FY)
1993
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
Molecular biological analysis of cytoskeletal associated protein in bile stasis.
Principal Investigator
TANDA Mariko
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Gastroenterology
Research Institution
Sapporo Medical University, School of Medicine
腫瘍マーカーの基礎的臨床的研究
Principal Investigator
西 信三
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hokkaido University
消化器癌における細胞接着分子の遺伝子及び機能解析と診断応用
Principal Investigator
Principal Investigator
谷内 昭
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
CEAの癌特異性の解明:大腸粘膜におけるその産生動態の生理と病理
Principal Investigator
松岡 雄治
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Fukuoka University
細胞間接着分子CEAおよびBGPの大腸腺管形成における役割と癌化に伴う異常
Principal Investigator
杉山 敏郎
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
膵癌の高危険群選別を目的とした超微量腫瘍細胞の特異的検出系の開発
Principal Investigator
今井 浩三
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
Gastroenterology
Research Institution
Sapporo Medical University
胃潰瘍再生上皮における細胞間接着分子発現とH^+,K^+-ATPaseの関連
Principal Investigator
杉山 敏郎
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Gastroenterology
Research Institution
Sapporo Medical University
腫瘍マ-カ-の基礎的臨床的研究
Principal Investigator
西 信三
Project Period (FY)
1991
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hokkaido University
CEAの癌特異性の解明:大腸粘膜におけるその産生動態の生理と病理
Principal Investigator
松岡 雄治
Project Period (FY)
1991
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Fukuoka University
消化器癌腫瘍マ-カ-分子のtransgenicマウスを用いた機能解析
Principal Investigator
Principal Investigator
谷内 昭
Project Period (FY)
1991
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
イディオタイプ・ネットワ-クを応用した免疫療法の基礎
Principal Investigator
辻崎 正幸
Project Period (FY)
1991
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
Association of H. pylori with immunological aspects of chronic gastritis
Principal Investigator
Principal Investigator
YACHI Akira
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Gastroenterology
Research Institution
Sapporo Medical College
The analysis of immune response and cytotoxic mechanism with use of anti-ICAM-1 monoclonal antibodies
Principal Investigator
TSUJISAKI Masayuki
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
内科学一般
Research Institution
Sapporo Medical College
Analysis of amyloidosis by novel amyloid-related protein gene.
Principal Investigator
IAMI Kohzoh
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
内科学一般
Research Institution
Sapporo Medical College
Study on the mechanisms of shedding of CEA into the serum by experimental system
Principal Investigator
HOSHI Hideki
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Gastroenterology
Research Institution
Sapporo Medical College
腫瘍マ-カ-およびその遺伝子の構造解析ならびに臨床応用
Principal Investigator
西 信三
Project Period (FY)
1990
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hokkaido University
CEA遺伝子ファミリ-の機能ならびに発現調節機構の解析
Principal Investigator
Principal Investigator
谷内 昭
Project Period (FY)
1990
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
イディオタイプ・ネットワ-クを応用した免疫療法の基礎
Principal Investigator
辻崎 正幸
Project Period (FY)
1990
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
腫瘍マーカーおよびその遺伝子の構造解析ならびに臨床応用
Principal Investigator
西 信三
Project Period (FY)
1989
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hokkaido University
消化器系抗原とその遺伝子に関する免疫学的・分子生物学的研究ならびに新しい応用
Principal Investigator
Principal Investigator
谷内 昭
Project Period (FY)
1989
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
CEA関連抗原遺伝子の分子生物学的解析および産物の機能
Principal Investigator
HINODA Yuji
Project Period (FY)
1989
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
抗イディオタイプ・モノクローナル抗体を用いた新しい癌の免疫療法の基礎
Principal Investigator
今井 浩三
Project Period (FY)
1989
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
Effect of Campylobacter Pylori upon Immunological Conditions of Chronic Gastritis.
Principal Investigator
Principal Investigator
YACHI Akira
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Gastroenterology
Research Institution
Sapporo Medical College
Detection of Novel Amyloid-Associated Protein by Monoclonal Antibody and its Gene Analysis
Principal Investigator
IMAI Kohzoh
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
内科学一般
Research Institution
Sapporo Medical College
腫瘍マーカーおよびその遺伝子の構造解析ならびに臨床応用
Principal Investigator
西 信三
Project Period (FY)
1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hokkaido University
消化器系癌抗原とその遺伝子に関する免疫学的・分子生物学的研究なよびに新しい応用
Principal Investigator
Principal Investigator
谷内 昭
Project Period (FY)
1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
抗イディオタイプならびに改造分子モノクローナル抗体を用いた癌の新しい診断の基礎
Principal Investigator
日野田 裕治
Project Period (FY)
1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
消化器系癌抗原とその遺伝子に関する免疫学的・分子生物学的研究ならびに新しい応用
Principal Investigator
Principal Investigator
谷内 昭
Project Period (FY)
1987
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
分子生物学的・免疫学的方法を用いた肝および大腸前癌マーカーの解析と新しい診断法
Principal Investigator
今井 浩三
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
Analysis of the auto-antibody in the serum from patients by use of anti-idiotypic monoclonal antibodies.
Principal Investigator
Principal Investigator
YACHI Akira
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
内科学一般
Research Institution
Sapporo Medical College
ヒト癌細胞増殖抑制に働くモノクローナル抗体を応用した新しい癌の治療法に関する研究
Principal Investigator
今井 浩三
Project Period (FY)
1986
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
モノクローナル抗体を用いたCEAの免疫学的・分子生物学的研究ならびに新しい応用
Principal Investigator
Principal Investigator
谷内 昭
Project Period (FY)
1985
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
Preparation of human monoclonal antibodies using human B cell producing autoantibodies and analyses of novel autoantigens.
Principal Investigator
Principal Investigator
YACHI Akira
Project Period (FY)
1985 – 1986
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
内科学一般
Research Institution
Sapporo Medical College
モノクローナル抗体を用いたCEAの免疫学的・分子生物学的研究ならびに新しい応用
Principal Investigator
Principal Investigator
谷内 昭
Project Period (FY)
1984 – 1986
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Sapporo Medical University
# of Projects (Dsc)
# of Projects (Asc)
1.
IMAI Kohzoh
(60117603)
# of Collaborated Projects :
21results
# of Collaborated Products :
0results
2.
HINODA Yuji
(10165128)
# of Collaborated Projects :
13results
# of Collaborated Products :
0results
3.
西 信三
(20001894)
# of Collaborated Projects :
9results
# of Collaborated Products :
0results
4.
SUGIYAMA Toshiro
(00196768)
# of Collaborated Projects :
8results
# of Collaborated Products :
0results
5.
松岡 雄治
(70078773)
# of Collaborated Projects :
8results
# of Collaborated Products :
0results
6.
森 武貞
(60028496)
# of Collaborated Projects :
7results
# of Collaborated Products :
0results
7.
TSUJISAKI Masayuki
(50217311)
# of Collaborated Projects :
5results
# of Collaborated Products :
0results
8.
高橋 俊雄
(50079828)
# of Collaborated Projects :
5results
# of Collaborated Products :
0results
9.
小路 敏彦
(20039811)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
10.
YABANA Tsuyoshi
(70045491)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
11.
遠藤 康夫
(60010302)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
12.
平井 秀松
(30000889)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
13.
葛巻 暹
(80091445)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
14.
山下 克子
(70030905)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
15.
池原 征夫
(70037612)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
16.
村田 長芳
(60020765)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
17.
宮木 美知子
(20085624)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
18.
ITOH Fumio
(90223180)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
19.
ENDO Takao
(40191928)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
20.
武田 和久
(50033080)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
21.
谷口 直之
(90002188)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
22.
名倉 宏
(90022821)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
23.
神奈木 玲児
(80161389)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
24.
及川 信三
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
25.
HOSHI Hideki
(90219163)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
26.
TANDA Mariko
(40240931)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
27.
酒井 正春
(50162269)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
28.
上出 利光
(00160185)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
29.
藤井 暢弘
(90133719)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
30.
木幡 陽
(30030852)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
31.
加藤 康夫
(90185877)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
32.
中里 紘
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
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