YACHI Akira 谷内昭

Researcher Number	50045324
Affiliation (based on the past Project Information) *help	1993 : 札幌医科大学, 医学部, 学長 1988 – 1993 : 札幌医科大学, 教授 1986 – 1992 : 札幌医科大学, 医学部, 教授 1990 – 1991 : 札幌医大, 医学部, 教授 1986 : Sapporo Medical College, Department of Medicine, 医学部, 教授 1985 : 札幌医科大学, 医, 教授
Review Section/Research Field	Principal Investigator 内科学一般 / Gastroenterology Except Principal Investigator Gastroenterology / 内科学一般
Keywords	Principal Investigator CEA / モノクローナル抗体 / 糖鎖構造 / Campylobacter pylori / 慢性胃炎 / ヘリコバクタ・ピロリ菌 / モノクロ-ナル抗体 / セレクチンファミリー / 自己抗体 / 高感度微量測定法 … More Except Principal Investigator CEA / モノクローナル抗体 / モノクロナル抗体 / 抗イディオタイプ抗体 / 腫瘍マ-カ- / 腫瘍マーカー / AFP / 大腸癌 / モノクロ-ナル抗体 / 放射免疫局在診断 / ワクチン効果 / RT-PCR法 / 腫瘍免疫 / Alzheimer's disease / Monoclonal antibody / 肝癌 / イディオタイプ・ネットワ-ク / 抗原・内部イメ-ジ / 免疫療法 / ICAM-1 / GPI-アンカー / Amyloidosis / アミロイド-シス / 癌胎児性抗原 / New amyloid-related protein / 再生上皮 / BGP / Biliary glycoprotein I / AA蛋白 / 胃がん / 腸上皮化生 / metastasis and invasion of cancer cells / NCAM / β蛋白 / ムチン抗原遺伝子 / アミロイドーシス / Carcinoembryonic antigen / アルツハイマー病 / キメラ抗体 / 血中放出機序 / Mn-SOD / 新しい治療法 / イディオタイプネットワーク / 腫瘍細胞 / 早期診断 / GPI結合型蛋白質 / Membrane antigen / 膜抗原 / ヘリコバクタ・ピロリ / Amyloid associated protein / 癌抗原 / PCR / 大腸粘膜crypt / 動物モデル / GST-P / cytotoxic mechanism / neural cell adhesion molecule / 続発性アミロイド-シス / 染色体9番長腕31領域 / MnーSOD / 癌遺伝子 / チロシン脱リン酸化酵素 / 血中遊離抗原 / Protein tyrosine phosphatase / Cytoskeletal protein / アミロイド関連蛋白遺伝子 / インタ-フェロン / circulating antigen / Differentiation / in situ hybridization / 胆汁うっ滞 / beta-protein / アルファフエトプロテイン / 抗原のインターナルイメージ / regeneration / 細胞接着活性 / AM34抗原遺伝子 / 胃潰瘍 / DNAプローブ / gastric ulcer / Nonspecific crossreacting antigen / adhesion modecule / Fight junction / 接着分子 / 癌の転移・臓器浸潤 / PTPH1 / transfectoma / 抗体複合体 / carcinoembryonic antigen(CEA) / AA protein / ICAMー1 / 膵炎 / β-蛋白 / 新アミロイド関連蛋白 / PTPH1遺伝子 / アルツハイマ-病 / 正常大腸粘膜 / アミロイド / Amyloid-related protein gene / c-myc / Adhesion molecule / tight junciton / Bile stasis / 抗合成ペプチドモノクローナル抗体 / 膵癌 / Collagen gel / GSTーP / アミロイド蛋白 / 癌細胞増殖抑制 / ミサイル療法 / 殺細胞機序 / tight junction / TPR-MET再構成 / アミロイド関連蛋白 / PTPH1 gene / 癌特異性 / 腺癌関連抗原 / αーフェトプロテイン / 前癌病変マーカー / 糖鎖の癌性変化 / DNAクロ-ニング / アモロイド関連蛋白 / Mechanisms of shedding / H^+,K^+-ATPase / NCA / MUSE11 / 細胞骨格 Less

Research Projects
(37results)
Co-Researchers
(32People)

消化器癌における細胞接着分子の遺伝子および機能解析と診断応用Principal Investigator
- Principal Investigator
  
  谷内昭
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
CEAの癌特異性の解明:大腸粘膜におけるその産生動態の生理と病理
- Principal Investigator
  
  松岡雄治
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Fukuoka University
腸上皮化生・胃がんへの進展におけるヘリコバクタ感染とTPR-MET再構成の関連
- Principal Investigator
  
  杉山敏郎
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
Molecular biological analysis of cytoskeletal associated protein in bile stasis.
- Principal Investigator
  
  TANDA Mariko
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University, School of Medicine
腫瘍マーカーの基礎的臨床的研究
- Principal Investigator
  
  西信三
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
消化器癌における細胞接着分子の遺伝子及び機能解析と診断応用Principal Investigator
- Principal Investigator
  
  谷内昭
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
CEAの癌特異性の解明:大腸粘膜におけるその産生動態の生理と病理
- Principal Investigator
  
  松岡雄治
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Fukuoka University
細胞間接着分子CEAおよびBGPの大腸腺管形成における役割と癌化に伴う異常
- Principal Investigator
  
  杉山敏郎
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
膵癌の高危険群選別を目的とした超微量腫瘍細胞の特異的検出系の開発
- Principal Investigator
  
  今井浩三
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
胃潰瘍再生上皮における細胞間接着分子発現とH^+,K^+-ATPaseの関連
- Principal Investigator
  
  杉山敏郎
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
腫瘍マ-カ-の基礎的臨床的研究
- Principal Investigator
  
  西信三
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
CEAの癌特異性の解明:大腸粘膜におけるその産生動態の生理と病理
- Principal Investigator
  
  松岡雄治
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Fukuoka University
消化器癌腫瘍マ-カ-分子のtransgenicマウスを用いた機能解析Principal Investigator
- Principal Investigator
  
  谷内昭
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
イディオタイプ・ネットワ-クを応用した免疫療法の基礎
- Principal Investigator
  
  辻崎正幸
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
Association of H. pylori with immunological aspects of chronic gastritisPrincipal Investigator
- Principal Investigator
  
  YACHI Akira
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical College
The analysis of immune response and cytotoxic mechanism with use of anti-ICAM-1 monoclonal antibodies
- Principal Investigator
  
  TSUJISAKI Masayuki
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Sapporo Medical College
Analysis of amyloidosis by novel amyloid-related protein gene.
- Principal Investigator
  
  IAMI Kohzoh
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Sapporo Medical College
Study on the mechanisms of shedding of CEA into the serum by experimental system
- Principal Investigator
  
  HOSHI Hideki
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical College
腫瘍マ-カ-およびその遺伝子の構造解析ならびに臨床応用
- Principal Investigator
  
  西信三
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
CEA遺伝子ファミリ-の機能ならびに発現調節機構の解析Principal Investigator
- Principal Investigator
  
  谷内昭
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
イディオタイプ・ネットワ-クを応用した免疫療法の基礎
- Principal Investigator
  
  辻崎正幸
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
腫瘍マーカーおよびその遺伝子の構造解析ならびに臨床応用
- Principal Investigator
  
  西信三
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
消化器系抗原とその遺伝子に関する免疫学的・分子生物学的研究ならびに新しい応用Principal Investigator
- Principal Investigator
  
  谷内昭
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
CEA関連抗原遺伝子の分子生物学的解析および産物の機能
- Principal Investigator
  
  HINODA Yuji
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
抗イディオタイプ・モノクローナル抗体を用いた新しい癌の免疫療法の基礎
- Principal Investigator
  
  今井浩三
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
Effect of Campylobacter Pylori upon Immunological Conditions of Chronic Gastritis.Principal Investigator
- Principal Investigator
  
  YACHI Akira
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical College
Detection of Novel Amyloid-Associated Protein by Monoclonal Antibody and its Gene Analysis
- Principal Investigator
  
  IMAI Kohzoh
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Sapporo Medical College
腫瘍マーカーおよびその遺伝子の構造解析ならびに臨床応用
- Principal Investigator
  
  西信三
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hokkaido University
消化器系癌抗原とその遺伝子に関する免疫学的・分子生物学的研究なよびに新しい応用Principal Investigator
- Principal Investigator
  
  谷内昭
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
抗イディオタイプならびに改造分子モノクローナル抗体を用いた癌の新しい診断の基礎
- Principal Investigator
  
  日野田裕治
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
消化器系癌抗原とその遺伝子に関する免疫学的・分子生物学的研究ならびに新しい応用Principal Investigator
- Principal Investigator
  
  谷内昭
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
分子生物学的・免疫学的方法を用いた肝および大腸前癌マーカーの解析と新しい診断法
- Principal Investigator
  
  今井浩三
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
Analysis of the auto-antibody in the serum from patients by use of anti-idiotypic monoclonal antibodies.Principal Investigator
- Principal Investigator
  
  YACHI Akira
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  Sapporo Medical College
ヒト癌細胞増殖抑制に働くモノクローナル抗体を応用した新しい癌の治療法に関する研究
- Principal Investigator
  
  今井浩三
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
モノクローナル抗体を用いたCEAの免疫学的・分子生物学的研究ならびに新しい応用Principal Investigator
- Principal Investigator
  
  谷内昭
- Project Period (FY)
  1985
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University
Preparation of human monoclonal antibodies using human B cell producing autoantibodies and analyses of novel autoantigens.Principal Investigator
- Principal Investigator
  
  YACHI Akira
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  Sapporo Medical College
モノクローナル抗体を用いたCEAの免疫学的・分子生物学的研究ならびに新しい応用Principal Investigator
- Principal Investigator
  
  谷内昭
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Sapporo Medical University

1. IMAI Kohzoh (60117603)

# of Collaborated Projects : 21results

# of Collaborated Products : 0results
2. HINODA Yuji (10165128)

# of Collaborated Projects : 13results

# of Collaborated Products : 0results
3. 西信三 (20001894)

# of Collaborated Projects : 9results

# of Collaborated Products : 0results
4. SUGIYAMA Toshiro (00196768)

# of Collaborated Projects : 8results

# of Collaborated Products : 0results
5. 松岡雄治 (70078773)

# of Collaborated Projects : 8results

# of Collaborated Products : 0results
6. 森武貞 (60028496)

# of Collaborated Projects : 7results

# of Collaborated Products : 0results
7. TSUJISAKI Masayuki (50217311)

# of Collaborated Projects : 5results

# of Collaborated Products : 0results
8. 高橋俊雄 (50079828)

# of Collaborated Projects : 5results

# of Collaborated Products : 0results
9. 小路敏彦 (20039811)

# of Collaborated Projects : 4results

# of Collaborated Products : 0results
10. YABANA Tsuyoshi (70045491)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
11. 遠藤康夫 (60010302)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
12. 平井秀松 (30000889)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
13. 葛巻暹 (80091445)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
14. 山下克子 (70030905)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
15. 池原征夫 (70037612)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
16. 村田長芳 (60020765)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
17. 宮木美知子 (20085624)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
18. ITOH Fumio (90223180)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
19. ENDO Takao (40191928)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
20. 武田和久 (50033080)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
21. 谷口直之 (90002188)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
22. 名倉宏 (90022821)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
23. 神奈木玲児 (80161389)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
24. 及川信三

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
25. HOSHI Hideki (90219163)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
26. TANDA Mariko (40240931)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
27. 酒井正春 (50162269)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
28. 上出利光 (00160185)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
29. 藤井暢弘 (90133719)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
30. 木幡陽 (30030852)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
31. 加藤康夫 (90185877)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
32. 中里紘

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

YACHI Akira 谷内 昭

Research Projects

Co-Researchers

消化器癌における細胞接着分子の遺伝子および機能解析と診断応用Principal Investigator

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消化器癌における細胞接着分子の遺伝子及び機能解析と診断応用Principal Investigator

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消化器癌腫瘍マ-カ-分子のtransgenicマウスを用いた機能解析Principal Investigator

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Association of H. pylori with immunological aspects of chronic gastritisPrincipal Investigator

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YACHI Akira 谷内昭