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IMAI KOHZOH  今井 浩三

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… Alternative Names

今井 浩三

IMAI Kohzoh  今井 浩三

高橋 徹  タカハシ トオル

IAMI Kohzoh  今井 加三

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Researcher Number 60117603
Other IDs
External Links
Affiliation (Current) 2020: 札幌医科大学, その他部局等, 名誉教授
2020: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), 臨床研究所, 顧問
Affiliation (based on the past Project Information) *help 2018: 東京大学, 医科学研究所, 客員教授
2016: 地方独立行政法人神奈川県立病院機構, 神奈川県立がんセンター(臨床研究所)・その他部局, 顧問
2016: 東京大学, 医科学研究所, 客員教授
2015 – 2016: 東京大学, 医科学研究所, 特任研究員
2011 – 2014: 東京大学, 医科学研究所, 特任教授 … More
2010 – 2011: 東京大学, 医科学研究所, 教授
2003 – 2009: 札幌医科大学, 学長
1993 – 2004: 札幌医科大学, 医学部, 教授
2003: 札幌医科大学, 医学部, 学長
2002: SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE PROF., 医学部・大学院・医学研究科, 教授
2002: 札幌医科大学, 大学院・医学部, 教授
1995: 札幌医科大学, 医学部, 助手
1992: 札幌医大, 1内, 講師
1991 – 1992: 札幌医科大学, 医学部, 助教授
1990 – 1991: 札幌医科大学, 1内, 講師
1990: 札幌医大, 医学部, 講師
1986 – 1990: Sapporo Medical College, Department of Medicine, 医学部, 講師
1987 – 1988: 札幌医大, 第一内科, 講師
1986: 札幌医大, 医学部, 講師
1986: 札幌医科大学, 第1内科教室, 講師 Less
Review Section/Research Field
Principal Investigator
Gastroenterology / 内科学一般 / Biological Sciences / Gastroenterology / Tumor diagnosis / 膠原病・アレルギー・感染症内科学 / Tumor therapeutics
Except Principal Investigator
Gastroenterology / Gastroenterology / 内科学一般 … More / Biological Sciences / Laboratory medicine / Hematology / Radiation science / 細胞死(アポトーシス) / Pathological medical chemistry Less
Keywords
Principal Investigator
モノクローナル抗体 / DNAメチル化 / 分子標的治療 / 消化器癌 / モノクロ-ナル抗体 / 遺伝子不安定性 / ムチン分子 / ムチン抗原 / MUC1 / CTL … More / 膵癌 / マトリライシン / 遺伝子診断 / ErbB-2 / アポトーシス / シグナル伝達機構 / エピジェネティクス / メチル化 / 腫瘍マーカー / 若手支援 / 遺伝子改変マウス / ゲノムコーホート研究 / 次世代分子解析技術 / アカデミア創薬 / がん / 癌 / 臨床 / アミロイド-シス / Amyloidosis / Alzheimer's disease / Immuno-PCR / ICAM-1 / ムチン遺伝子 / 胃前癌病変 / mucin genes / gastric pre-cancerous lesions / MSI / 消火器癌 / 抗イディオタイプ抗体 / CEA / イディオタイプネットワーク / 抗原のインターナルイメージ / ムチン関連癌抗原 / 遺伝子クロ-ニング / 癌診断 / ムチン・コア蛋白 / MUCー1遺伝子 / エピト-プ解析 / 抗ムチン抗原 / 糖鎖異常 / MuC-1遺伝子 / エピトープ / タンデム・リピート / 膵炎 / 早期診断 / PCR / MUSE11 / 腫瘍細胞 / ムチン抗原遺伝子 / RT-PCR法 / 抗ムチン抗体 / 脱糖鎖 / 腫瘍関連ムチン / MUC-1 / CDX2 / hMLH1 / AGL1 / Differential Display / alpha 1, 6 fucosy1 transferase / RET / AFPトランスジェニックマウス / がん進展 / がんの浸潤転移 / 遺伝子治療 / 家族性胃癌 / DNAミスマッチ修復酵素遺伝子 / α1, 6フコース転移酵素遺伝子 / がん関連遺伝子 / 家族集積性胃癌 / 新遺伝子 / RDA法 / DNA解析 / 遺伝子解析 / 消化器がん / 早期大腸がん / 膵がん / 予後因子 / 食道バレット粘膜 / 消火器がん / DCC / KAI-1 / ヒト抗体 / 免疫療法 / ヒト型抗体 / 免疫治療 / モロクローナル抗体 / ヒストン修飾 / 個別化医療 / 遺伝子発現 / 分子標的 / Wntシグナル / 国際研究者交流 / 病理形態学 / ゲノム・エピゲノム解析支援 / 個別化がん予防 / 国際交流 / ATL発症予防 / 分子疫学コーホート研究 / がん化学予防 / ATL発がん機序 / ATL発症リスク / がん分子標的薬剤 / 胃癌 / 大腸癌 / 肝癌 / エピゲノム / DNAメチル化 / バイオマーカー / マイクロRNA / ゲノム / トランスレーショナルリサーチ / マイクロアレイ / マクロアレイ / がん幹細胞 / 遺伝子 / 多発性骨髄腫 / Drug Delivery System / 橋渡し研究 / 骨髄微小環境 / 免疫細胞 / DDS / 抗体医薬 / 核酸治療 / 癌細胞増殖抑制 / 新しい治療法 / 前癌病変マーカー / 癌遺伝子 / DNAプローブ / アモロイド関連蛋白 / アルツハイマ-病 / β蛋白 / アミロイド関連蛋白 / アミロイド / 続発性アミロイド-シス / β-蛋白 / Amyloid associated protein / Monoclonal antibody / beta-protein / アミロイドーシス / アミロイド関連蛋白遺伝子 / アルツハイマー病 / AA蛋白 / 新アミロイド関連蛋白 / アミロイド蛋白 / AM34抗原遺伝子 / Amyloid-related protein gene / AA protein / New amyloid-related protein / MUSE11抗原 / Pancreas cancer / Antigen MUSE 11 / 腸上皮化生 / 腸型胃癌 / バレット食道 / 分子機構解析 / Intestinal metaplasia / gastric cancer / Barett esohagus / DNA修復遺伝子 / メチレーション / メチレ-ション / genomic instability / DNA repair genes / methylation / マイクロサテライト不安定性 / 免疫学的診断 / 癌ワクチン / 標的遺伝子変異 / β2-マイクログロブリン / 変異オリゴペプチド / Microsatellite instability / Gastrointestinal tumor / Immunological diagnosis / Cancer vaccine / ヒストン / メチル化異常 / 癌発生 / 前癌病変 / Genetic instability / DNA methylation / Epigenetics / Molecular target therapy / Gastrointestinal cancer / ゲノムコホート研究 … More
Except Principal Investigator
モノクローナル抗体 / アポトーシス / BAG-1 / モノクロ-ナル抗体 / 抗体療法 / 抗イディオタイプ抗体 / CEA / ヒストンアセチル化 / バイスペシフィック抗体 / がん遺伝子産物 / 画像診断 / イディオタイプ抗体 / 免疫療法 / 転移 / 肝癌 / マウスモノクローナル抗体 / 血清診断 / Bcl-2 / JNK / apoptosis / DNAメチル化 / 分子生物学 / ガングリオシド抗原 / 腫瘍免疫 / イディオタイプ・ネットワ-ク / 抗原・内部イメ-ジ / ワクチン効果 / Carcinoembryonic antigen / Differentiation / 遺伝子治療 / 分子標的治療 / マトリライシン / PKC / Metastasis / Apoptosis / 分子標的 / 癌 / 腫瘍関連抗原 / 糖鎖抗原 / 発癌遺伝子産物 / ヘリコバクタ・ピロリ菌 / 慢性胃炎 / Campylobacter pylori / Monoclonal antibody / LC-PTP / IL-2 / 癌治療 / G-CSF / アノイキス / BAD / 細胞運動能 / 放射線 / ICAM-1 / MEK / p300 / CBP / Histone acetylation / エピジェネティクス / MCA / DNA methylation / chromatin / mitochondria / T-fimbrin / DNA damage / 自己抗体 / CEA遺伝子 / NCA / BGP1 / AFP / ras / Biliary glycoprotein I / Nonspecific crossreacting antigen / in situ hybridization / transfectoma / 抗合成ペプチドモノクローナル抗体 / ガングリオシ-ド抗原 / 消化器癌マ-カ- / トランスジェニックマウス / BGP / 糖鎖転移酵素遺伝子 / Adhesion molecule / Collagen gel / がんの早期診断法 / がんの質的診断法 / がん免疫 / がんの遺伝子治療 / がんの分子標的治療 / がん化学療法 / がんの放射線療法 / がん治療 / がん診断 / 放射線治療 / 大腸癌 / 浸潤 / レチノイン酸 / Barrett上皮, / 食道腺癌, / ムチン / Barrett上皮 / 食道腺癌 / 硫酸化ムチン / シアル酸化ムチン / SHP-2 / Anoikis / ドラッグデリバリーシステム / 新しい物理療法 / トランスレーショナル・リサーチ / 分子創薬 / トランスレーショナルリサーチ / 新しい物療法 / ostepontin / CD44 / インターフェロン / FGFR-1 / 抗体 / 治療 / ヒストンメチル化 / 小胞体ストレス / 酸化ストレス / クロマチン構造 / SUVH20 / マイクロRNA / 分子診断 / 肝臓学 / 抗体治療 / 分子改変 / 糖鎖構造 / 高感度微量測定法 / 遺伝子クローニング / ヒトモノクローナル抗体 / 消化器系癌抗原 / 癌遺伝子 / 癌胎児性蛋白 / 分子生物学的研究 / ヒトーマウスキメラ抗体 / 腫瘍関連状原 / 糖領抗原 / 消化器癌関連抗原 / 分子生物学的解析 / ヒト-マウスキメラ抗体 / 腺癌関連抗原 / カンピロバクタ・ピロリ菌 / 局所免疫応答 / 胃潰瘍 / 十二指腸潰瘍 / 組織学的重症度 / Helicobacter pylori / Chronic Gastritis / Monoclinal antibody / Local immune response / ヘリコバタタ・ピロリ菌 / 病態解析 / 胃液 / SIgA / SIgA抗体 / H. pylori / Chronic gastritis / Analysis of the Disease / Gastric juice / sIgA / 血中放出機序 / 膜抗原 / tight junction / tight junciton / インタ-フェロン / 動物モデル / Mechanisms of shedding / Membrane antigen / Fight junction / 蛋白質脱リン酸化 / SH-PTP2 / タンパク質脱リン酸化酵素 / SH2ドメイン / ホスホチロシン / 染色体マップ / Protein-tyrosine phosphatase / SHPTP2 / Chromosome assignment / genome DNA / tyrosine kinase / 国際学術 / 海外派遣 / 細胞社会学 / シグナル伝達 / 細胞周期 / 薬品設計 / ウイルス発癌 / 細胞接着 / 化学発癌 / 情報交換 / ドラッグデザイン / 癌遺伝子治療 / 癌化学療法 / 細胞増殖 / International Scientific Research / Cancer / Information Exchange / Signal Transduction / Cell Cycle / Cell Adhesion / Drug Design / Gene Therapy / WT1遺伝子 / 分化 / wt1腫瘍抑制遺伝子 / 細胞分化 / 蛋白-蛋白相互作用 / WT1 / anoikis / Golgi apparatus / Cell motility / マトリックスメタロプロテアーゼ / TIMP / 潰瘍性大腸炎 / PCR / 免疫組織染色 / TIMP-1 / TIMP-2 / 潰瘍形成 / Matrilysin / Matrix metalloproteinase / RT-PCR / Immunostaining / ulcerative colitis / extracellular matrix / 癌関連抗原 / IFN-gamma / IL-3 / radiotherapy / metastasis / radiation sensitivity / c-erb B-2 / 民族疫学 / コーホート研究 / 症例対照研究 / 分子疫学 / 臨床疫学 / 危険・防御要因 / 予防 / 分析疫学 / 分子疫学コーホート / 予防啓発 / 広報活動 / 遺伝子・環境交互作用 / コホート研究 / 宿主・環境交互作用 / 宿主・環境要因 / 国際比較研究 / 大規模共同研究 / 症例・対照研究 / Ethnoepidemiology / Cohort study / Case-control study / Molecular epidemiology / Clinical epidemiology / Cancer prevention / Risk factors / Protective factors / 放射線誘発アポトーシス / 放射線感受性 / ERKシグナル / ミトコンドリア膜電位 / カスペース活性化 / ウイルスベクター / Caspase8 / radiation-induced apoptosis / radiosensitivity / ERK signal / mitochondrial membrame potential / caspase activation / 転写活性 / HAT / HDAC / Transcriptional activation / Histone acetyltransferase / Cancer therapy / 炎症性腸疾患 / 腫瘍マーカー / 分子マーカー / 癌抑制遺伝子 / 炎症 / 前癌病変 / DNA methylations / Epigenetics / inflammatory bowel disease / Tumor marker / クロマチン / がん抑制遺伝子 / histone acetyiation / tumor suppressor gene / epigenetics / BH3 / ミトコンドリア / Bcl-xL / 14-3-3 / BH3-only蛋白 / Akt / BH-3 only protein / phosphorylation / TOF-Mass / chaperone / DNA損傷 / 抗癌剤感受性 / 細胞周期制御 / アクチン結合蛋白 / 肝臓癌 / Cell Cycle Control / Chemosensitivity / Actin binding protein / Liver cancer / DNA障害 / DNA修復 / ヒストンアセチル / ヒストンリン酸化 / ROS / 自己抗原 / ヒト型モノクローナル抗体 / エピトープ / Autoantibody / Autoantigen / Human monoclonal antibody / anti-idiotypic antibody / autoimmune disease / モデル動物作製 / ゲノム編集 / 病理形態解析 / 生理機能解析 / 分子探索・プロファイリング / 分子プロファイリング / 分子探索・ブロファイリング / 行動解析 / 生体試料支援 / コホート / 臨床検体 / 一般健常人 / 大規模ゲノム解析 / 大規模ゲノム解析・オミックス解析 / オミックス解析 / 生命科学連携推進協議会 / コホート・生体試料支援 / 先端バイオイメージング支援 / 先端モデル動物支援 / 先進ゲノム解析研究推進 / 各プラットフォーム間の連携 / 各プラットフォーム問の連携 / 中皮腫 / インテレクチン Less
  • Research Projects

    (77 results)
  • Research Products

    (390 results)
  • Co-Researchers

    (347 People)
  •  がん研究分野の特性等を踏まえた支援活動Principal Investigator

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      2016
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      The University of Tokyo
  •  先端モデル動物支援プラットフォームPrincipal Investigator(Support)Ongoing

    • Principal Investigator(Support)
      今井 浩三
    • Project Period (FY)
      2016 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources
    • Research Institution
      The University of Tokyo
  •  コホート・生体試料支援プラットフォームPrincipal Investigator(Support)Ongoing

    • Principal Investigator(Support)
      今井 浩三
    • Project Period (FY)
      2016 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources
    • Research Institution
      The University of Tokyo
  •  生命科学連携推進協議会Principal Investigator(Support)Ongoing

    • Principal Investigator(Support)
      今井 浩三
    • Project Period (FY)
      2016 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources
    • Research Institution
      The University of Tokyo
  •  A fundamental study to develop novel targeted drug delivery systems for multiple myeloma therapyPrincipal Investigator

    • Principal Investigator
      Imai Kohzoh
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor therapeutics
    • Research Institution
      The University of Tokyo
  •  Analysis of transcription factor that regulates intelectin-1 expression in mesothelioma

    • Principal Investigator
      Tsuji Shoutaro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Kanagawa Cancer Center Research Institute
  •  Identification of specific cancer stem cell markers for diagnosisPrincipal Investigator

    • Principal Investigator
      IMAI Kohzoh
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor diagnosis
    • Research Institution
      The University of Tokyo
  •  Development of novel gastrointestinal cancer diagnostic system based on large epige-nome analysis.Principal Investigator

    • Principal Investigator
      IMAI Kohzoh
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Tumor diagnosis
    • Research Institution
      The University of Tokyo
  •  Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative AreasPrincipal Investigator

    • Principal Investigator
      IMAI Kohzoh, 中村 祐輔
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      The University of Tokyo
  •  がん研究分野の特性等を踏まえた支援活動Area Organizer

    • Area Organizer
      今井 浩三
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
  •  Establishment of a treatment for advanced hepatocellular carcinoma using a tri-functional specific antibody

    • Principal Investigator
      SASAKI Shigeru
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  Molecular diagnosis by evaluating histone methylation

    • Principal Investigator
      ADACHI Masaaki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Sapporo Medical University
  •  Immunotherapy using humanized monoclonal antibodyPrincipal Investigator

    • Principal Investigator
      IMAI Kohzoh
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Sapporo Medical University
  •  Molecular mechanisms of epigenetic alterations in gastrointestinal cancer and application to diagnosis and therapyPrincipal Investigator

    • Principal Investigator
      IMAI Kohzoh
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  消化器癌におけるWntシグナルネットワーク破綻の評価システムの構築Principal Investigator

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  進行肝癌に対するインターフェロン,抗FGFR-1ヒト抗体併用療法

    • Principal Investigator
      佐々木 茂
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  Development of a new anticancer therapy by reguration of machinery for epigenetics

    • Principal Investigator
      ADACHI Masaaki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Sapporo Medical University
  •  New therapeutic strategies for treatment of cancer based on basic research

    • Principal Investigator
      UEDA Ryuzo
    • Project Period (FY)
      2004 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya City University
  •  肝癌に対するインターフェロン,抗オステオポンチン抗体,抗CD44抗体併用療法

    • Principal Investigator
      小関 至
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  Diagnostic and therapeutic application of checkpoint gene T-fimbrin in gastrointestinal

    • Principal Investigator
      SASAKI Yasushi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  抗ErbB-2抗体によるアポトーシス誘導におけるシグナル伝達機構の解析と治療応用Principal Investigator

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Sapporo Medical University
  •  Development of a novel therapy for gastrointestinal cancer using epigenetic alterations as a target.

    • Principal Investigator
      TOYOTA Minoru
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  Analysis of proapoptotic functions of BH3-only protein BAD

    • Principal Investigator
      ADACHI Masaaki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      細胞死(アポトーシス)
    • Research Institution
      Sapporo Medical University
  •  抗ErbB-2抗体によるアポトーシス誘導におけるシグナル伝達機構の解析Principal Investigator

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      内科学一般
    • Research Institution
      Sapporo Medical University
  •  DEVELOPMENT OF NEW CANCER THERAPY USING HISTONE DEACETHYLASE INHIBITORS

    • Principal Investigator
      ADACHI Masaaki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      SAPPORO MEDICAL UNIVERSITY
  •  Aberrant methylation of inflammatory bowel disease and its application to risk assessment of cancer

    • Principal Investigator
      TOYOTA Minoru
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  Microsatellite instability and aberrant methylation in gastrointestinal cancer and its application to molecular target therapyPrincipal Investigator

    • Principal Investigator
      IMAI Kohzoh
    • Project Period (FY)
      2001 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  消化器がんの進展に関連する分子と治療・予後に関する研究Principal Investigator

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Sapporo Medical University
  •  Analysis of molecular mechanism of premalignant lesion of the stomach using genomic instability and new mucin gene.Principal Investigator

    • Principal Investigator
      IMAI Kohzoh
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  Immunelogical diagnosis of MSI-positive gastrointestinal cancer and application for cancer vaccinePrincipal Investigator

    • Principal Investigator
      IMAI Kohzoh
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  がん進展に関わる分子の診断・治療への応用Principal Investigator

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Sapporo Medical University
  •  Epidemiologic studies on environmental and host-specific factors for human cancers

    • Principal Investigator
      TAJIMA Kazuo
    • Project Period (FY)
      1999 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Aichi Cancer Center
  •  Investigation of radiosensitizers with radiation-induced apoptosis

    • Principal Investigator
      HAREYAMA Masato
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Radiation science
    • Research Institution
      SAPPORO MEDICAL UNIVERSITY
  •  チロシンホスファターゼSHP2の制御に基づく免疫強化療法の開発

    • Principal Investigator
      ADACHI Masaaki
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Sapporo Medical University
  •  The new approach of radiotherapy for the prevention of metastasis

    • Principal Investigator
      HAREYAMA Masato
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      SAPPORO MEDICAL UNIVERSITY, SCHOOL OF MEDICINE
  •  食道・胃接合部癌発生におけるムチン分子ファミリー遺伝子及び糖鎖の役割

    • Principal Investigator
      ENDO Takao
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  家族集積性胃癌関連遺伝子のRDA法による同定Principal Investigator

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  AnalysIs of molecular mechanism of gastric pre-cancerous lesions by using new mucin genesPrincipal Investigator

    • Principal Investigator
      IMAI Kohzoh
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  Suppression of tumor metastasis through anti-apoptotic molecules BCL-2/BAG-1

    • Principal Investigator
      ADACHI Masaaki
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Sapporo Medical University School of Medicine
  •  Relation of matrixmetalloproteinases and infalammatory bowel disease

    • Principal Investigator
      ITOH Fumio
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  マトリライシン(MMP-7)の発現制御による大腸癌の転移抑制に関する研究

    • Principal Investigator
      伊東 文生
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Sapporo Medical University
  •  Development of a supersensitive detection method for pancreas cancer associated antigen and tumor suppressor gene by using immuno-PCR.Principal Investigator

    • Principal Investigator
      IMAI Kohzoh
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University, School of Medicine
  •  REGULATION OF HEMATOPOIETIC CELLS VIA TUMOR SUPPRESSOR GENE WT1

    • Principal Investigator
      ADACHI Masaki
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Sapporo Medical University School of Medicine
  •  がん診断治療の基礎研究

    • Principal Investigator
      濱岡 利之
    • Project Period (FY)
      1994 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  腫瘍関連ムチンのがん診断治療への応用Principal Investigator

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Sapporo Medical University
  •  Information Exchange on Cancer Research with North American

    • Principal Investigator
      YAMAMOTO Tadashi
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      The University of Tokyo
  •  Significance and functional analysis of protein-tyrosine phosphatases expressed in hematopoietic disorders.

    • Principal Investigator
      ADACHI Masaaki
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Sapporo Medical University School of Midicine
  •  モノクローナル抗体による腫瘍関連抗原の検出と治療への応用

    • Principal Investigator
      高橋 利忠
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Aichi Cancer Center Research Institute
  •  細胞間接着分子CEAおよびBGPの大腸腺管形成における役割と癌化に伴う異常

    • Principal Investigator
      杉山 敏郎
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  新しい癌関連ムチンコア蛋白抗原の遺伝子およびエピトープ解析と診断応用Principal Investigator

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Sapporo Medical University
  •  膵癌の高危険群選別を目的とした超微量腫瘍細胞の特異的検出系の開発Principal Investigator

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  モノクロ-ナル抗体による腫瘍関連抗原の検出と治療への応用

    • Principal Investigator
      高橋 利忠
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Aichi Cancer Center Research Institute
  •  消化器癌腫瘍マ-カ-分子のtransgenicマウスを用いた機能解析

    • Principal Investigator
      谷内 昭
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  イディオタイプ・ネットワ-クを応用した免疫療法の基礎

    • Principal Investigator
      辻崎 正幸
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  新しいムチン関連癌抗原コア蛋白の遺伝子クロ-ニングと臨床応用への基礎Principal Investigator

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Sapporo Medical University
  •  Association of H. pylori with immunological aspects of chronic gastritis

    • Principal Investigator
      YACHI Akira
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical College
  •  Analysis of amyloidosis by novel amyloid-related protein gene.Principal Investigator

    • Principal Investigator
      IAMI Kohzoh
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Sapporo Medical College
  •  Study on the mechanisms of shedding of CEA into the serum by experimental system

    • Principal Investigator
      HOSHI Hideki
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical College
  •  モノクロ-ナル抗体による腫瘍関連抗原の検出と治療への応用

    • Principal Investigator
      高橋 利忠
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Aichi Cancer Center Research Institute
  •  イディオタイプ・ネットワ-クを応用した免疫療法の基礎

    • Principal Investigator
      辻崎 正幸
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  新しいムチン関連癌抗原コア蛋白の遺伝子クロ-ニングと臨床応用への基礎Principal Investigator

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Sapporo Medical University
  •  消化器系抗原とその遺伝子に関する免疫学的・分子生物学的研究ならびに新しい応用

    • Principal Investigator
      YACHI Akira
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  CEA関連抗原遺伝子の分子生物学的解析および産物の機能

    • Principal Investigator
      HINODA Yuji
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  抗イディオタイプ・モノクローナル抗体を用いた新しい癌の免疫療法の基礎Principal Investigator

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  Effect of Campylobacter Pylori upon Immunological Conditions of Chronic Gastritis.

    • Principal Investigator
      YACHI Akira
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical College
  •  Detection of Novel Amyloid-Associated Protein by Monoclonal Antibody and its Gene AnalysisPrincipal Investigator

    • Principal Investigator
      IMAI Kohzoh
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Sapporo Medical College
  •  消化器系癌抗原とその遺伝子に関する免疫学的・分子生物学的研究なよびに新しい応用

    • Principal Investigator
      谷内 昭
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  癌の診断に有用なモノクローナル抗体の作成とその対応抗原の解析

    • Principal Investigator
      高橋 利忠
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Aichi Cancer Center Research Institute
  •  抗イディオタイプならびに改造分子モノクローナル抗体を用いた癌の新しい診断の基礎

    • Principal Investigator
      日野田 裕治
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  消化器系癌抗原とその遺伝子に関する免疫学的・分子生物学的研究ならびに新しい応用

    • Principal Investigator
      谷内 昭
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  癌の診断に有用なモノクローナル抗体の作成とその対応抗原の解析

    • Principal Investigator
      高橋 利忠
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Aichi Cancer Center Research Institute
  •  分子生物学的・免疫学的方法を用いた肝および大腸前癌マーカーの解析と新しい診断法Principal Investigator

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  Analysis of the auto-antibody in the serum from patients by use of anti-idiotypic monoclonal antibodies.

    • Principal Investigator
      YACHI Akira
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      Sapporo Medical College
  •  癌の診断に有用なモノクローナル抗体の作成とその対応抗原の解析

    • Principal Investigator
      高橋 利忠
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Aichi Cancer Center Research Institute
  •  ヒト癌細胞増殖抑制に働くモノクローナル抗体を応用した新しい癌の治療法に関する研究Principal Investigator

    • Principal Investigator
      今井 浩三
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University
  •  Preparation of human monoclonal antibodies using human B cell producing autoantibodies and analyses of novel autoantigens.

    • Principal Investigator
      YACHI Akira
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      Sapporo Medical College
  •  モノクローナル抗体を用いたCEAの免疫学的・分子生物学的研究ならびに新しい応用

    • Principal Investigator
      谷内 昭
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Sapporo Medical University

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 Other

All Journal Article Presentation Book Patent

  • [Book] がん研究分野の特性等を踏まえた支援活動 研究成果報告書2017

    • Author(s)
      がん研究分野の特性等を踏まえた支援活動 研究代表者 今井浩三
    • Total Pages
      166
    • Publisher
      東京大学消費生活協同組合
    • Data Source
      KAKENHI-WRAPUP-16H01690
  • [Book] The Role of DNA Methylation in the Genetics and Epigenetics of Multiple Myelome2014

    • Author(s)
      Yasui H, Ishida T, Imai K
    • Publisher
      Nova Science Publishers
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Book] Multiple myeloma: risk factors, diagnosis and treatments.(The role of DNA methylation in the genetics and epigenetics of multiple myeloma.)2014

    • Author(s)
      Yasui H, Ishida T, Imai K.
    • Total Pages
      249
    • Publisher
      Nova Science Publishers
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Book] 疾患モデルの作製と利用-がん. 第4章 呼吸器系, 第1項 肺2012

    • Author(s)
      横平政直, 今井田克己.
    • Total Pages
      633
    • Publisher
      エル・アイ・シー
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Book] 2.予防 CQ3「5α還元酵素阻害薬は化学予防薬として有用か?」 前立腺癌診療ガイドライン2012年版(日本泌尿器科学会編)2012

    • Author(s)
      高橋 悟
    • Publisher
      金原出版株式会社
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Book] 消化管と遺伝子異常. 消化管病理標本の読み方改訂2版2008

    • Author(s)
      豊田実、今井浩三、篠村恭久, 中村眞一. (編集)
    • Publisher
      日本メディカルセンター
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Book] エピジェネティクス-メチル化とヒストン修飾. がんの分子標的治療2008

    • Author(s)
      今井浩三、豊田実, 鶴尾隆. (編集)
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Book] The role and clinical implication of DNA methylation in gastrointestinal cancer. Recent Advances in Gastrointestinal Carcinogenesis.2006

    • Author(s)
      Toyota M, Suzuki H, Maruyama R, Tarasawa I, Yamamoto E, Tokino T, Imai K, Shinomura Y
    • Publisher
      Edited by Bamba H and Ota S, Transworld Research Network, Kerala, India
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Intensity-specific and modified effects of physical activity on serum adiponectin in a middle-aged population2019

    • Author(s)
      Yuichiro Nishida, Yasuki Higaki, Naoto Taguchi, Megumi Hara, Kazuyo Nakamura, Hinako Nanri, Takeshi Imaizumi, Tatsuhiko Sakamoto, Chisato Shimanoe, Mikako Horita, Koichi Shinchi, Keitaro Tanaka
    • Journal Title

      Journal of the Endocrine Society

      Volume: 3 Issue: 1 Pages: 13-26

    • DOI

      10.1210/js.2018-00255

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01554, KAKENHI-PROJECT-16H06277
  • [Journal Article] 髄液バイオマーカーとしての“脳型”トランスフェリン2019

    • Author(s)
      村上友太、齋藤 清、高橋浩一、荒木信夫、橋本康弘
    • Journal Title

      自律神経

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Journal Article] CD271 is a negative prognostic factor and essential for cell proliferation in lung squamous cell carcinoma2019

    • Author(s)
      Mai Mochizuki, Mao Nakamura, Rie Shibuya, Toshimasa Okazaki, Jiro Abe, Takayuki Nakagawa, Satomi Takahashi, Tomoko Yamazaki, Takayuki Imai, Atsushi Takano, Hiroyuki Ito, Tomoyuki Yokose, Yohei Miyagi, Yataro Daigo, Ikuro Sato, Kennichi Satoh, Kazuo Sugamu
    • Journal Title

      Laboratory investigation

      Volume: -

    • DOI

      10.1038/s41374-019-0246-5

    • Description
      in press
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K15035, KAKENHI-PROJECT-16H06277
  • [Journal Article] Different types of suppression-burst patterns in patients with epilepsy of infancy with migrating focal seizures (EIMFS).2019

    • Author(s)
      Yoshitomi S, Takahashi Y, Imai K, Koshimizu E, Miyatake S, Nakashima M, Saitsu H, Matsumoto N, Kato M, Fujita T, Ishii A, Hirose S, Inoue Y.
    • Journal Title

      Seizure

      Volume: 65 Pages: 118-123

    • DOI

      10.1016/j.seizure.2019.01.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10080, KAKENHI-PROJECT-15H02548, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16K15532, KAKENHI-PROJECT-16H06276
  • [Journal Article] Revised Adult T-Cell Leukemia-Lymphoma International Consensus Meeting Report.2019

    • Author(s)
      Cook LB, Fuji S, Hermine O, Bazarbachi A, Ramos JC, Ratner L, Horwitz S, Fields P, Tanase A, Bumbea H, Cwynarski K, Taylor G, Waldmann TA, Bittencourt A, Marcais A, Suarez F, Sibon D, Phillips A, Lunning M, Farid R, Imaizumi Y, Choi I, Ishida T, Ishitsuka
    • Journal Title

      J Clin Oncol.

      Volume: 37 Pages: 677-687

    • DOI

      10.1200/jco.18.00501

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04713, KAKENHI-PROJECT-16H05248, KAKENHI-PROJECT-16H06277
  • [Journal Article] Quinidine therapy and therapeutic drug monitoring in four patients with KCNTI mutations.2019

    • Author(s)
      Yoshitomi S, Takahashi Y, Yamaguchi T, Oboshi T, Horino A, Ikeda H, Imai K, Okanishi T, Nakashima M, Saitsu H, Matsumoto N, Yoshimoto J, Fujita T, Ishii A, Hirose S, Inoue Y.
    • Journal Title

      Epileptic Disorders

      Volume: 21 Issue: 1 Pages: 48-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Journal Article] Chiroptical Inversion of Europium(Ⅲ) Complexes by Changing a Remote Stereogenic Center of a C2-symmetric Bispyrrolidinoindoline Manifold2018

    • Author(s)
      Tomoaki Taniguchi, Akira Tsubouchi, Yuki Imai, Junpei Yuasa, Hiroki Oguri
    • Journal Title

      J. Org. Chem.

      Volume: 83 Issue: 24 Pages: 15284-15296

    • DOI

      10.1021/acs.joc.8b02550

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-17H05386, KAKENHI-PUBLICLY-18H04388, KAKENHI-PROJECT-16H06276
  • [Journal Article] Different clonal dynamics of chronic myeloid leukaemia betwecn bone marrow and the central nervous system2018

    • Author(s)
      Ogawa M, Yokoyama K, Hirano M, Jimbo K, Ochi K, Kawamata T, Ohno N, Shimizu E, Yokoyama N, Yamaguchi R, Imoto S, Uchimaru K, Takahashi N, Miyano S, Imai Y, Tojo A
    • Journal Title

      Br J Haematol

      Volume: - Pages: 842-845

    • DOI

      10.1111/bjh.15065

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K21012, KAKENHI-PROJECT-16H06277, KAKENHI-PLANNED-15H05912
  • [Journal Article] 脳脊髄液減少症(特発性低髄液圧症候群)と脳型トランスフェリン2018

    • Author(s)
      村上友太、高橋浩一、星 京香、伊藤浩美、齋藤 清、宮嶋雅一、新井 一、美馬達夫、橋本康弘
    • Journal Title

      日本頭痛学会誌

      Volume: 45 Issue: 1 Pages: 25-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Journal Article] Chronic inflammatory demyelinating polyneuropathy in adult T-cell leukemia-lymphoma patients following allogeneic stem cell transplantation.2018

    • Author(s)
      Hirano M, Jimbo K, Ogawa M, Ochi K, Makiyama J, Kawamata T, Yokoyama K, Tanaka T, Inamoto Y, Yamano Y, Fukuda T, Uchimaru K, Imai Y, Tojo A.
    • Journal Title

      Bone Marrow Transplant

      Volume: 53 Issue: 11 Pages: 1470-1473

    • DOI

      10.1038/s41409-018-0202-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05323, KAKENHI-PROJECT-16H06277
  • [Journal Article] Autologous peripheral blood stem cell transplantation for double-refractory myeloma with <i>K-RAS</i> and <i>N-RAS</i> mutations2018

    • Author(s)
      神保光児、横山和明、小川弥穂、平野光人、越智清純、小林真之、遊佐 希、清水英悟、川俣豊隆、大野伸広、山口 類、井元清哉、古川洋一、宮野 悟、今井陽一、東條有伸.
    • Journal Title

      Jpn. J. Clin. Hematol.

      Volume: 58 Issue: 12 Pages: 2380-2385

    • DOI

      10.11406/rinketsu.58.2380

    • NAID

      130006308839

    • ISSN
      0485-1439, 1882-0824
    • Year and Date
      2018-01-13
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K21012, KAKENHI-PROJECT-16J02129, KAKENHI-PROJECT-16H06277
  • [Journal Article] Initial scverity of major depression and efficacy of new generation antidepressants : Individual-participant data meta-analysis.2018

    • Author(s)
      Furukawa TA, Maruo K, Noma H, Tanaka S, Imai H, Shinohara K, Ikeda K, Yamawaki S, Levine SZ, Goldberg Y, Leucht S, Cipriani A
    • Journal Title

      Acta Psychiatr Scand

      Volume: 印刷中 Pages: 450-458

    • DOI

      10.1111/acps.12886

    • Description
      in press
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293347, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17K19808, KAKENHI-PROJECT-17H04324, KAKENHI-PROJECT-16K15565
  • [Journal Article] Silencing PRDM14 expression by an innovative RNAi therapy inhibits stemness, tumorigenicity, and metastasis of breast cancer.2017

    • Author(s)
      Taniguchi H, Hoshino D, Moriya C, Zembutsu H, Nishiyama N, Yamamoto H, Kataoka K, Imai K.
    • Journal Title

      Oncotarget

      Volume: 6(28) Issue: 29 Pages: 10448-10458

    • DOI

      10.18632/oncotarget

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15017, KAKENHI-PROJECT-15H04321, KAKENHI-PROJECT-15K15034, KAKENHI-PROJECT-26670639, KAKENHI-PROJECT-15K09514, KAKENHI-PROJECT-15K10112, KAKENHI-PROJECT-16K15598, KAKENHI-PROJECT-16K15625, KAKENHI-PROJECT-16K15691, KAKENHI-PROJECT-16K19336, KAKENHI-PROJECT-16K08679, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-16H05139
  • [Journal Article] Establishment of a refined culture mothod for rat colon organoids.2017

    • Author(s)
      Isshiki H, Arimura Y, Nagaishi K, Kawakami K, Onodera K, Yamashita K, Naishiro Y, Fujimiya M, Imai K, Shinomura Y.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 489 Issue: 3 Pages: 305-311

    • DOI

      10.1016/j.bbrc.2017.05.142

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08972, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297
  • [Journal Article] Inhibition of PRDM14 expression in pancrcatic cancer suppresses cancer stem-like properties and liver mctastasis in mice.2017

    • Author(s)
      Moriya C, Taniguchi H, Imai K.
    • Journal Title

      Carcinogenesis

      Volume: 38 Issue: 6 Pages: 638-648

    • DOI

      10.1093/carcin/bgx040

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297
  • [Journal Article] Epidemiological and clinical features of adult T-cell leukemia-lymphoma (ATL) in Japan, 2010-2011 : a nationwide survey2017

    • Author(s)
      Nosaka K, Iwanaga M, Imaizumi Y, Ishitsuka K, Ishizawa K, Ishida Y, Amano M, Ishida T, Uike N, Utsunomiya A, Ohshima K, Kawai K, Tanaka J, Tokura Y, Tobinai K, Watanabe T, Uchimaru K, Tsukasaki K
    • Journal Title

      Cancer Sci

      Volume: 108 Pages: 2478-2486

    • DOI

      10.1111/cas.13398

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H04713, KAKENHI-PROJECT-15K08609, KAKENHI-PROJECT-16H06277
  • [Journal Article] 大脳皮質基底核変性症の1剖検例2017

    • Author(s)
      八木 宣泰, 堀内 公成, 小西 高志, 今井 昇, 芹澤 正博, 笠原 正男, 高尾 昌樹, 小張 昌宏
    • Journal Title

      臨床神経学

      Volume: 57 Pages: 617-617

    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Journal Article] Cancer Transitional Care for Terminally Ill Cancer Patients Can Reduce the Number of Emergency Admissions and Emergency Department Visits.2017

    • Author(s)
      Shimada N, Ishiki H, Iwase S, Chiba T, Fujiwara N, Watanabe A, Kinkawa J, Nojima M, Tojo A, Imai K.
    • Journal Title

      American Journal of Hospiec & Palliative Mcdicine

      Volume: 34 Issue: 9 Pages: 831-837

    • DOI

      10.1177/1049909116658641

    • Description
      Epub ahead of print
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297
  • [Journal Article] The effect of forced expression of mutated K-RAS gene on gastrointestinal cancer cell lines and the IGF-1R targeting therapy.2017

    • Author(s)
      Matsunaga Y, Adachi Y, Sasaki Y, Koide H, Motoya M, Nosho K, Takagi H, Yamamoto H, Sasaki S, Arimura Y, Tokino T, Carbone DP, Imai K, Shinomura Y.
    • Journal Title

      Mol Careinog

      Volume: VOL. 56 Issue: 2 Pages: 515-526

    • DOI

      10.1002/mc.22513

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297
  • [Journal Article] HEG1 is a novel mucin-like membrane protein that serves as a diagnostic and therapeutic target for malignant mesothelioma.2017

    • Author(s)
      Tsuji S, Washimi K, Kageyama T, Yamashita M, Matsuura R, Yokose T, Kamada Y, Hayashi H, Morohoshi T, Tsuura Y, Yusa T, Sato T, Togayachi A, Narimatsu H, Nagasaki T, Nakamoto K, Moriwaki Y, Misawa H, Hiroshima K, Miyagi Y, Imai K.
    • Journal Title

      Sci Rep

      Volume: 7 Pages: 45768-45768

    • DOI

      10.1038/srep45768

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460692, KAKENHI-PROJECT-15K21370, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297
  • [Journal Article] Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer.2016

    • Author(s)
      Nosho K, Sukawa Y, Adachi Y, Ito M, Mitsuhashi K, Kurihara H, Kanno S, Yamamoto I, Ishigami K, Igarashi H, Maruyama R, Imai K, Yamamoto H, Shinomura Y.
    • Journal Title

      World J Gastroenterol

      Volume: 22 Pages: 557-566

    • DOI

      10.3748/wjg.v22.i2.557

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14397, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297
  • [Journal Article] Cancer stem cells in human gastrointestinal cancer.2016

    • Author(s)
      Taniguchi H, Moriya C, Igarashi H, Saitoh A, Yamamoto H, Adachi Y, Imai K.
    • Journal Title

      Cancer Sci

      Volume: 107 Issue: 11 Pages: 1556-1562

    • DOI

      10.1111/cas.13069

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297
  • [Journal Article] Seasonal allergies and serial changes of serum levels of IgG4 in casestreated with maintenance therapy for IgG4-related disease.2016

    • Author(s)
      Yamamoto M, Takahashi H, Shimizu Y, Yajima H, Suzuki C, Naishiro Y, Imai K, Shinomura Y.
    • Journal Title

      Mod Rheumatol.

      Volume: 26 Issue: 1 Pages: 161-2

    • DOI

      10.3109/14397595.2014.995893

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297
  • [Journal Article] Report of the Japan Diabetes Society (JDS)/Japanese Cancer Association (JCA) Joint Committee on Diabetes and Cancer, Second Report2016

    • Author(s)
      Goto A, Noto H, Noda M, Ueki K, Kasuga M, Tajima N, Ohashi K, Sakai R, Tsugane S, Hamajima N, Tajima K, Imai K, Nakagama H.
    • Journal Title

      Diabeto Int.

      Volume: 7 Pages: 12-15

    • DOI

      10.1007/s13340-016-0257-z

    • NAID

      130005142004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26640101
  • [Journal Article] A genomic screen for long noncoding RNA genes epigenetically silenced by aberrant DNA methylation in colorectal cancer.2016

    • Author(s)
      Kumegawa K, Maruyama R, Yamamoto E, Ashida M, Kitajima H, Tsuyada A, Niinuma T, Kai M, Yamano H, Sugai T, Tokino T, Shinomura Y, Imai K, Suzuki H.
    • Journal Title

      Scientific Reports

      Volume: 6 Pages: 26699-26699

    • DOI

      10.1038/srep26699

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-15K15584, KAKENHI-PROJECT-15K08973, KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297
  • [Journal Article] Report of the Japan diabetes society/Japanese cancer association joint committee on diabetes and cancer, Second report.2016

    • Author(s)
      Goto A, Noto H, Noda M, Ueki K, Kasuga M, Tajima N, Ohashi K, Sakai R, Tsugane S, Hamajima N, Tajima K, Imai K, Nakagama H.
    • Journal Title

      Cancer Science

      Volume: 107(3) Issue: 3 Pages: 369-371

    • DOI

      10.1111/cas.12889

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-26290043, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297
  • [Journal Article] Expression of membrane complement regulators, CD46, CD55 and CD59, in mesothelial cells of patients on peritoneal dialysis therapy.2016

    • Author(s)
      Tuboly E, Futakuchi M, Varga G, Erces D, Tokes T, Meszaros A, Kaszaki J, Suzui M, Imai M, Okada A, Okada N, Boros M, Okada H.
    • Journal Title

      Microbiol Immunol

      Volume: 60 Pages: 302-309

    • DOI

      10.1111/1348-0421.12338

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25430154, KAKENHI-PROJECT-26462849, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15K06837
  • [Journal Article] The relationship between EZH2 expression and microRNA-31 in colorectal cancer and the role in evolution of the serrated pathway.2016

    • Author(s)
      Kurihara H, Maruyama R, Ishiguro K, Kanno S, Yamamoto I, Ishigami K, Mitsuhashi K, Igarashi H, Ito M, Tanuma T, Sukawa Y, Okita K, Hasegawa T, Imai K, Yamamoto H, Shinomura Y, Nosho K.
    • Journal Title

      Oncotarget

      Volume: 7 Issue: 11 Pages: 12704-120717

    • DOI

      10.18632/oncotarget.7260

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14397, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-16K07145, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297
  • [Journal Article] Association of variations in HLA class Ⅱ and other loci with susceptibility to EGFR-mutated lung adenocarcinoma.2016

    • Author(s)
      Shiraishi K, Takahashi A, Takano A, Watanabe Y, Hishida T, Tsuchihara K, Miyagi Y, Tanaka K, Imai K, Minamiya Y, Sakamoto H, Inazawa J, Nakamura Y, Yoshida T, Yokota J, Matsuda F, Matsuo K, Daigo Y, Kubo M, Kohno T, et. al.
    • Journal Title

      Nature Communications

      Volume: 7 Pages: 12451-12451

    • DOI

      10.1038/ncomms12451

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05908, KAKENHI-PLANNED-15H05911, KAKENHI-PUBLICLY-16H01583, KAKENHI-PROJECT-15H05670, KAKENHI-PROJECT-15K14429, KAKENHI-PROJECT-15K10275, KAKENHI-PROJECT-16K08928, KAKENHI-PROJECT-15K14406, KAKENHI-PROJECT-16H06277
  • [Journal Article] Contextual niche signals towards colorectal tumor progression by mesenchymal stem cell in the mouse xenograft model2015

    • Author(s)
      Nakagaki S, Arimura Y, Nagaishi K, Isshiki H, Nasuno M, Watanabe S, Idogawa M, Yamashita K, Naishiro Y, Adachi Y, Suzuki H, Fujimiya M, Imai K, Shinomura Y.
    • Journal Title

      J Gastroenterol

      Volume: Epub ahead of print

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Journal Article] 抗体治療 特集「DDSがもたらした新しい臨床の風景」2015

    • Author(s)
      佐々木茂, 篠村恭久, 今井浩三
    • Journal Title

      Drug Delivery System

      Volume: 30 Issue: 1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Microsatellite instability : an update2015

    • Author(s)
      Yamamoto H, Imai K
    • Journal Title

      Archives of Toxicology

    • Description
      【掲載確定】 in press
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Association of Fusobacterium nucleatum with clinical and molecular features in colorectal serrated pathway.2015

    • Author(s)
      Ito M, Kanno S, Nosho K, Sukawa Y, Mitsuhashi K, Kurihara H, Igarashi H, Takahashi T, Tachibana M, Takahashi H, Yoshii S, Takenouchi T, Hasegawa T, Okita K, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y.
    • Journal Title

      Int J Cancer

      Volume: 137 Pages: 1258-1268

    • DOI

      10.1002/ijc.29488

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K14397, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-26640101
  • [Journal Article] Role of interleukin-32 in the mechanism of chronic inflammation in IgG4-related disease and as a predictive biomarker for drug-free remission.2015

    • Author(s)
      Shimizu Y, Yamamoto M, Yajima H, Suzuki C, Naishiro Y, Takahashi H, Imai K, Shinomura Y.
    • Journal Title

      Modern Rheumatology

      Volume: 26(3) Pages: 391-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Journal Article] Dietary Patterns and Serum Gamma-Glutamyl Transferase in Japanese Men and Women2015

    • Author(s)
      Nanri H, Hara M, Nishida Y, Shimanoe C, Nakamura K, Higaki Y, Imaizumi T, Taguchi N, Sakamoto T, Horita M, Shinchi K, Kokaze A, Tanaka K.
    • Journal Title

      Journal of Epidemiology

      Volume: 25 Issue: 5 Pages: 378-386

    • DOI

      10.2188/jea.je20140158

      10.2188/jea.JE20140158

    • NAID

      130005067867

    • ISSN
      0917-5040, 1349-9092
    • Description
      in press
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25870517, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26293141
  • [Journal Article] 抗体医薬2015

    • Author(s)
      安井寛, 今井浩三
    • Journal Title

      DDS研究30年

      Volume: PHARMA TECH JAPAN 臨時増刊号,31(2)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Reversing the ageing phenotypes of klotho mice by ablating the p16INK4a tumour suppressor.2015

    • Author(s)
      Seidai Sato, Yuka Kawamata, Akiko Takahashi, Yoshinori Imai, Aki Hanyu, Atsushi Okuma, Masaki Takasugi, Kimi Yamakoshi, Hiroyuki Sorimachi, Hiroaki Kanda, Yuichi Ishikawa, Saburo Sone, Yasuhiko Nishioka, Naoko Ohtani and Eiji Hara
    • Journal Title

      nature communications

      Volume: 6 Pages: 1-10

    • DOI

      10.1038/ncomms8035

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-13J06532, KAKENHI-PROJECT-24650625, KAKENHI-PROJECT-26250028, KAKENHI-PROJECT-26670418, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-14J10280, KAKENHI-PROJECT-14J10710, KAKENHI-PROJECT-15K19421, KAKENHI-PROJECT-25290046
  • [Journal Article] Analysis of the molecular features of rectal carcinoid tumors to identify new biomarkers that predict biological malignancy.2015

    • Author(s)
      Mitsuhashi K, Yamamoto I, Kurihara H, Kanno S, Ito M, Igarashi H, Ishigami K, Sukawa Y, Tachibana M, Takahashi H, Tokino T, Maruyama R, Suzuki H, Imai K, Shinomura Y, Yamamoto H, Nosho K
    • Journal Title

      Oncotarget

      Volume: 6 Pages: 22114-22125

    • DOI

      10.18632/oncotarget.4294

    • NAID

      130005161488

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26640101
  • [Journal Article] 抗体治療2015

    • Author(s)
      佐々木茂, 篠村恭久, 今井浩三
    • Journal Title

      Drug Delivery System

      Volume: 30(1) Pages: 16-24

    • NAID

      130005066112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Journal Article] Screening of drugs to treat 8p11 myeloproliferative syndrome using patient-derived induced pluripotent stem cells with fusion gene CEP110-FGFR12015

    • Author(s)
      Yamamoto S, Otsu M, Matsuzaka E, Konishi C, Takagi H, Hanada S, Mochizuki S, Nakauchi H, Imai K, Tsuji K, Ebihara Y.
    • Journal Title

      Plos One

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Journal Article] Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis2015

    • Author(s)
      Mitsuhashi K, Nosho K, Sukawa Y, Matsunaga Y, Ito M, Kurihara H, Kanno S, Igarashi H, Naito T, Adachi Y, Tachibana M, Tanuma T, Maguchi H, Shinohara T, Hasegawa T, Imamura M, Kimura Y, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y.
    • Journal Title

      Oncotarget

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Journal Article] Clinicopathological and molecular characteristics of serrated lesions in Japanese elderly patients.2015

    • Author(s)
      Nosho K, Igarashi H, Ito M, Mitsuhashi K, Kurihara H, Kanno S, Yoshii S, Mikami M, Takahashi H, Kusumi T, Hosokawa M, Sukawa Y, Adachi Y, Hasegawa T, Okita K, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y
    • Journal Title

      Digestion

      Volume: 91(1) Issue: 1 Pages: 57-63

    • DOI

      10.1159/000368820

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25293289
  • [Journal Article] Epigenetic silencing of NTSR1 is associated with lateral and noninvasive growth of colorectal tumors.2015

    • Author(s)
      Kamimae S, Yamamoto E, Kai M, Niinuma T, Yamano HO, Nojima M, Yoshikawa K, Kimura T, Takagi R, Harada E, Harada T, Maruyama R, Sasaki Y, Tokino T, Shinomura Y, Sugai T, Imai K, Suzuki H
    • Journal Title

      Oncotarget.

      Volume: 6 Pages: 29975-29990

    • DOI

      10.18632/oncotarget.5034

    • NAID

      130005161526

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08973, KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-15K15584, KAKENHI-PROJECT-15K18431, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-25460420, KAKENHI-PROJECT-26640101
  • [Journal Article] Perceived stress and coping strategies in relation to body mass index: cross-sectional study of 12,045 Japanese men and women2015

    • Author(s)
      Shimanoe C, Hara M, Nishida Y, Nanri H, Otsuka Y, Nakamura K, Higaki Y, Imaizumi T, Taguchi N, Sakamoto T, Horita M, Shinchi K, Tanaka K.
    • Journal Title

      Plos One

      Volume: 12

    • DOI

      10.1371/journal.pone.0118105

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25870517, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15K01718, KAKENHI-PROJECT-26293141
  • [Journal Article] Immunohistochemical Characteristics of Surfactant Proteins A, B, C and D in Inflammatory and Tumorigenic Lung Lesions of F344 Rats2015

    • Author(s)
      Yokohira M, Yamakawa K, Nakano Y, Numano T, Furukawa F, Kishi S, Ninomiya F, Kanie S, Hitotsumachi H, Saoo K, Imaida K
    • Journal Title

      J Toxicol Pathol

      Volume: 27 Issue: 3+4 Pages: 175-182

    • DOI

      10.1293/tox.2014-0020

    • NAID

      130004713012

    • ISSN
      0914-9198, 1881-915X
    • Year and Date
      2015-12-11
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Everyday clinical practice in IgG4-related dacryoadenitis and/or sialadentist: Result from the SMART database.2015

    • Author(s)
      Yamamoto M, Yajima H, Takahashi H, Yokoyama Y, Ishigami K, Shimizu Y, Tabeya T, Suzuki C, Naishiro Y, Takano KI, Yamashita K, Hashimoto M, Keira Y, Honda S, Abe T, Suzuki Y, Mukai M,Himi T, Hasegawa T, Imai K, Shinomura Y
    • Journal Title

      Modern Rheumatology

      Volume: 27 Pages: 199-204

    • DOI

      10.3109/14397595.2014.950036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25861575, KAKENHI-PROJECT-15K10818, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26640101
  • [Journal Article] Role of interleukin-32 in the mechanism of chronic inflammation in IgG4-related disease and as a predictive biomarker for drug-free remission.2015

    • Author(s)
      Shimizu Y, Yamamoto M, Yajima H, Suzuki C, Naishiro Y, Takahashi H, Imai K, Shinomura Y.
    • Journal Title

      Modern Rheumatology

      Volume: 26(3) Pages: 391-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.2015

    • Author(s)
      Hirokawa M, Morita H, Tajima T, Takahashi A, Ashikawa K, Miya F, Shigemizu D, Ozaki K, Sakata Y, Nakatani D, Suna S, Imai Y, …, Kadowaki T, Nakamura Y, Nagai R, Komuro I, Kubo M
    • Journal Title

      Eur. J. Hum. Genet.

      Volume: 23 Pages: 374-380

    • DOI

      10.1038/ejhg.2014.110

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26000012
  • [Journal Article] Contextual niche signals towards colorectal tumor progression by mesenchymal stem cell in the mouse xenograft model2015

    • Author(s)
      Nakagaki S, Arimura Y, Nagaishi K, Isshiki H, Nasuno M, Watanabe S, Idogawa M, Yamashita K, Naishiro Y, Adachi Y, Suzuki H, Fujimiya M, Imai K, Shinomura Y
    • Journal Title

      J Gastroenterol

    • Description
      【掲載確定】 Epub ahead of print
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Low-frequency IL23R coding variant associated with Crohn’s disease susceptibility in Japanese subjects identified by personal genomics analysis.2015

    • Author(s)
      Onodera K, Arimura Y, Isshiki H, Kawakami K, Nagaishi K, Yamashita K, Yamamoto E, Niinuma T, Naishiro Y, Suzuki H, Imai K, Shinomura Y
    • Journal Title

      Plos One

      Volume: 10

    • DOI

      10.1371/journal.pone.0137801

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08972, KAKENHI-PROJECT-15K08973, KAKENHI-PROJECT-26460975, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25460954, KAKENHI-PROJECT-25460955, KAKENHI-PROJECT-26640101
  • [Journal Article] Establishment of patient-derived cancer xenografts2015

    • Author(s)
      Chijiwa T, Kawai K, Noguchi A, Sato H, Hayashi A, Cho H, Shiozawa M, Kishida T, Morinaga S, Yokose T, Katayama M, Takenaka N, Suemizu H, Yamada R, Nakamura Y, Ohtsu T, Takano Y, Imai K, Miyagi Y, Nakamura M
    • Journal Title

      Internatinal Journal of Oncology

      Volume: 47 Pages: 61-70

    • DOI

      10.3892/ijo.2015.2997

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26430097, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15H04287, KAKENHI-PROJECT-25430098, KAKENHI-PROJECT-26640101
  • [Journal Article] 抗体医薬2015

    • Author(s)
      安井寛, 今井浩三
    • Journal Title

      PHARMA TECH JAPAN

      Volume: 31(2) Pages: 94-101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Journal Article] Screening of drugs to treat 8p11 myeloproliferative syndrome using patient-derived induced pluripotent stem cells with fusion gene CEP110-FGFR12015

    • Author(s)
      Yamamoto S, Otsu M, Matsuzaka E, Konishi C, Takagi H, Hanada S, Mochizuki S, Nakauchi H, Imai K, Tsuji K, Ebihara Y
    • Journal Title

      Plos One

    • Description
      【掲載確定】 in press
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis2015

    • Author(s)
      Mitsuhashi K, Nosho K, Sukawa Y, Matsunaga Y, Ito M, Kurihara H, Kanno S, Igarashi H, Naito T, Adachi Y, Tachibana M, Tanuma T, Maguchi H, Shinohara T, Hasegawa T, Imamura M, Kimura Y, Hirata K, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y
    • Journal Title

      Oncotarget

    • Description
      【掲載確定】 in press
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Microsatellite instability:an update2015

    • Author(s)
      Yamamoto H, Imai K.
    • Journal Title

      Archives of Toxicology

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Journal Article] Association of microRNA-31-5p with clinical efficacy of anti-EGFR therapy in patients with metastatic colorectal cancer.2015

    • Author(s)
      Igarashi H, Kurihara H, Mitsuhashi K, Ito M, Okuda H, Kanno S, Naito T, Yoshii S, Takahashi H, Kusumi T, Hasegawa T, Sukawa Y, Adachi Y, Okita K, Hirata K, Imamura Y, Baba Y, Imai K, Suzuki H, Yamamoto H, Nosho K, Shinomura Y
    • Journal Title

      Annals of Surgical Oncology

      Volume: 14 Pages: 2640-2648

    • DOI

      10.1245/s10434-014-4264-7

    • Description
      Epub ahead of print
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25670371, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-26293290
  • [Journal Article] Panitumumab for locally advanced head and neck squamouse-cell carcinoma2015

    • Author(s)
      Ishiki H, Iwase S, Shimada N, Chiba T, Imai K.
    • Journal Title

      Lancet Oncology

      Volume: 16(4) Issue: 4

    • DOI

      10.1016/s1470-2045(15)70101-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
  • [Journal Article] Environmental carcinognensis-100th anniversary of creating cancer.2015

    • Author(s)
      Misa Imai, Okio Hino
    • Journal Title

      Cancer Science

      Volume: 106 Pages: 1483-1485

    • DOI

      10.1111/cas.12798

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26861341, KAKENHI-PROJECT-221S0001
  • [Journal Article] Conditioned mesenchymal stem cells produce pleiotropic gut trophic factors.2014

    • Author(s)
      Watanabe S, Arimura Y, Nagaishi K, Isshiki H, Onodera K, Nasuno M, Yamashita K, Idogawa M, Naishiro Y, Murata M, Adachi Y, Fujimiya M, Imai K, Shinomura Y
    • Journal Title

      Journal of Gastroenterology

      Volume: 49 Pages: 270-282

    • DOI

      10.1007/s00535-013-0901-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-24650632, KAKENHI-PROJECT-25460929, KAKENHI-PROJECT-25460954, KAKENHI-PROJECT-25460955
  • [Journal Article] MicroRNA-31 expression in relation to BRAF mutation, CpG island methylation and colorectal continuum in serrated lesions.2014

    • Author(s)
      Ito M, Mitsuhashi K, Igarashi H, Nosho K, Yamamoto H
    • Journal Title

      International Journal of Cancer

      Volume: (Epub ahead of print) Issue: 11 Pages: 2507-15

    • DOI

      10.1002/ijc.28920

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23300366, KAKENHI-PROJECT-23590920, KAKENHI-PUBLICLY-25134715, KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-25461705, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
  • [Journal Article] 大規模コホートを用いた大腸癌のノンコーディングRNA発現異常と生活習慣の分子疫学的解析2014

    • Author(s)
      能正勝彦, 五十嵐央祥, 伊藤美樹, 三橋慧, 栗原弘義, 菅野伸一, 内藤崇史, 須河安恭敬, 松永康孝, 足立靖, 野島正寛, 今井浩三, 丸山玲緒, 鈴木拓, 山本博幸, 篠村恭久
    • Journal Title

      日本癌病態治療研究会誌

      Volume: 20 Issue: 1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] The Use of Bone Marrow Stromal Cells (Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells) for Alveolar Bone Tissue Engineering : Basic Science to Clinical Translation2014

    • Author(s)
      Kagami H, Agata H, Inoue M, Asahina I, Tojo A, Yamashita N, Imai K.
    • Journal Title

      Tissue Engineering Part B : Reviews

      Volume: 20(3) Issue: 3 Pages: 229-232

    • DOI

      10.1089/ten.teb.2013.0578

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
  • [Journal Article] Rat strain differences in levels and effects of chronic inflammation due to intratracheal instillation of quartz on lung tumorigenesis induced by DHPN2014

    • Author(s)
      Nakano Y, Yokohira M, Hashimoto N, Yamakawa K, Kishi S, Ninomiya F, Kanie S, Saoo K, Imaida K
    • Journal Title

      Exp. Toxicol. Pathol

      Volume: 66

    • DOI

      10.1016/j.etp.2014.06.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] 総説 橋渡し研究の展開と我が国の医療2014

    • Author(s)
      今井浩三
    • Journal Title

      東京都病院薬剤師会雑誌

      Volume: 63(2) Pages: 5-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Journal Article] Analysis of DNA methylation in bowel lavage fluid for detection of colorectal cancer2014

    • Author(s)
      Harada T, Yamamoto E, Yamano HO, Nojima M, Maruyama R, Kumegawa K, Ashida M, Yoshikawa K, Kimura T, Harada E, Takagi R, Tanaka Y, Aoki H, Nishizono M, Nakaoka M, Tuyada A, Niinuma T, Kai M, Shimoda K, Shinomura Y, Sugai T, Imai K, Suzuki H.
    • Journal Title

      Cancer Prevention Research (Philadelphia, Pa.)

      Volume: 7(10) Issue: 10 Pages: 1002-10

    • DOI

      10.1158/1940-6207.capr-14-0162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461705, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
  • [Journal Article] Napsin A is possibly useful marker to predict the tumorigenic potential of lung bronchiolo-alveolar hyperplasia in F344 rats2014

    • Author(s)
      Yokohira M., Kishi S., Yamakawa K., Nakano Y., Ninomiya F., Kinouch S., Tanizawa J., Saoo K., Imaida K.
    • Journal Title

      Exp. Toxicol. Pathol

      Volume: 66 Pages: 117-23

    • DOI

      10.1016/j.etp.2013.11.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Overview and Future prospect of “Promotion plan for the platform of human resource development for cancer”2014

    • Author(s)
      Imai K.
    • Journal Title

      Juntendo Medical Journal

      Volume: 60 Issue: 3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] 人口動態に基づいた日本医療の未来予測-高齢多死社会の到来2014

    • Author(s)
      湯地晃一郎,井元清哉,山口類,宮野悟,上昌広,今井浩三
    • Journal Title

      南江堂臨床雑誌「外科」

      Volume: 76(5) Pages: 457-463

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Journal Article] Mesenchymal stem cells cancel azoxymethane-induced tumor initiation.2014

    • Author(s)
      Nasuno M, Arimura Y, Nagaishi K, Isshiki H, Onodera K, Nakagaki S, Watanabe S, Idogawa M, Yamashita K, Naishiro Y, Adachi Y, Suzuki H, Fujimiya M, Imai K, Shinomura Y
    • Journal Title

      STEM CELLS

      Volume: 32 Issue: 4 Pages: 913-25

    • DOI

      10.1002/stem.1594

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-24650632, KAKENHI-PROJECT-25460929, KAKENHI-PROJECT-25460954, KAKENHI-PROJECT-25460955, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
  • [Journal Article] Association of microRNA-31-5p with clinical efficacy of anti-EGFR therapy in patients with metastatic colorectal cancer2014

    • Author(s)
      Igarashi H, Kurihara H, Mitsuhashi K, Ito M, Okuda H, Kanno S, Naito T, Yoshii S, Takahashi H, Kusumi T, Hasegawa T, Sukawa Y, Adachi Y, Okita K, Hirata K, Imamura Y, Baba Y, Imai K, Suzuki H, Yamamoto H, Nosho K, Shinomura Y
    • Journal Title

      Annals of Surgical Oncology

    • Description
      Epub ahead of print
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Pharmaceutical and nutraceutical approaches for preventing liver carcinogenesis : chemoprevention of hepatocellular carcinoma using acyclic retinoid and branched-chain amino acids2014

    • Author(s)
      Shimizu M, Shirakami Y, Hanai T, Imai K, Suetsugu A, Takai K, Shiraki M, Moriwaki H.
    • Journal Title

      Mol Nutr Food Res

      Volume: 58 Pages: 124-135

    • DOI

      10.1002/mnfr.201300538

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24890081, KAKENHI-PROJECT-25460987, KAKENHI-PROJECT-25460988, KAKENHI-PROJECT-26460997, KAKENHI-PROJECT-26860498, KAKENHI-PROJECT-221S0001
  • [Journal Article] The effect of IGF-I receptor blockade for human esophageal squamous cell carcinoma and adenocarcinoma.2014

    • Author(s)
      Adachi Y, Ohashi H, Imsumran A, Yamamoto H, Matsunaga Y, Taniguchi H, Nosho K, Suzuki H, Sasaki Y, Arimura Y, Carbone DP, Imai K, Shinomura Y
    • Journal Title

      Tumor Biol

      Volume: 35 Issue: 2 Pages: 973-85

    • DOI

      10.1007/s13277-013-1131-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-24650632, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
  • [Journal Article] Association of microRNA-31-5p with clinical efficacy of anti-EGFR therapy in patients with metastatic colorectal cancer2014

    • Author(s)
      Igarashi H, Kurihara H, Mitsuhashi K, Ito M, Okuda H, Kanno S, Naito T, Yoshii S, Takahashi H, Kusumi T, Hasegawa T, Sukawa Y, Adachi Y, Okita K, Hirata K, Imamura Y, Baba Y, Imai K, Suzuki H, Yamamoto H, Nosho K, Shinomura Y.
    • Journal Title

      Annals of Surgical Oncology

      Volume: Epub ahead of print

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Journal Article] 人口動態に基づいた日本医療の未来予測-高齢多死社会の到来, 特集「超高齢者に対する外科治療の問題点」2014

    • Author(s)
      湯地晃一郎, 井元清哉, 山口類, 宮野悟, 上昌広, 今井浩三
    • Journal Title

      南江堂臨床雑誌「外科」

      Volume: 76 Issue: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Importance of the progesterone receptor (PR) and the epidermal growth factor receptor (EGFR), but not the estrogen receptor (ER), for chemically induced lung carcinogenesis in female A/J mice.2014

    • Author(s)
      Kishi S., Yokohira M., Yamakawa K., Saoo K., Imaida K.
    • Journal Title

      Oncol. Lett.

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] DNA synthesis inhibitors for the treatment of gastrointestinal cancer2014

    • Author(s)
      Yasui H, Tsurita G, Imai K
    • Journal Title

      Expert Opin Pharmacother

      Volume: 15 Issue: 16 Pages: 2361-2372

    • DOI

      10.1517/14656566.2014.958074

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591402, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
  • [Journal Article] Clinicopathological features and EGFR gene mutation status in elderly patients with resected non-small-cell lung cancer2014

    • Author(s)
      Nishii T, Yokose T, Miyagi Y, Daigo Y, Ito H, Isaka T, Imai K, Murakami S, Kondo T, Saito H, Oshita F, Yamada K, Matsukuma S, Tsuboi M, Nakayama H, Masuda M
    • Journal Title

      BMC Cancer

      Volume: 14 Pages: 610-610

    • DOI

      10.1186/1471-2407-14-610

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390145, KAKENHI-PROJECT-221S0001
  • [Journal Article] 総説 橋渡し研究の展開と我が国の医療2014

    • Author(s)
      今井浩三
    • Journal Title

      東京都病院薬剤師会雑誌

      Volume: 63 Issue: 2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Objectively measured physical activity and inflammatory cytokine levels in middle-aged Japanese people2014

    • Author(s)
      Nishida Y, Higaki Y, Taguchi N, Hara M, Nakamura K, Nanri H, Imaizumi T, Sakamoto T, Horita M, Shinchi K, Tanaka K.
    • Journal Title

      Prev Med

      Volume: 64 Pages: 81-87

    • DOI

      10.1016/j.ypmed.2014.04.004

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25870517, KAKENHI-PROJECT-26293141, KAKENHI-PROJECT-221S0001
  • [Journal Article] Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk2014

    • Author(s)
      Suzuki R, Yamamoto E, Nojima M, Maruyama R, Yamano HO, Yoshikawa K, Kimura T, Harada T, Ashida M, Niinuma T, Sato A, Nosho K, Yamamoto H, Kai M, Sugai T, Imai K, Suzuki H, Shinomura Y
    • Journal Title

      J Gastroenterol

      Volume: ([Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129
  • [Journal Article] がんエピゲノム異常を理解し、応用し、そして制御するために2014

    • Author(s)
      鈴木拓, 今井浩三
    • Journal Title

      実験医学

      Volume: 32 Issue: 19

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] The peroxisome proliferator-activated receptor(PPAR)a agonist fenofibrate suppresses chemically induced lung alveolar proliferative lesions in male obese hyperlipidemic mice2014

    • Author(s)
      Toshiya Kuno, Kazuya Hata, Manabu Takamatsu, Akira Hara, Yoshinobu Hirose, Satoru Takahashi, Katsumi Imaida, Takuji Tanaka
    • Journal Title

      Int. J. Mol. Sci

      Volume: 15 Pages: 9160-72

    • DOI

      10.3390/ijms15059160

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591159, KAKENHI-PROJECT-221S0001
  • [Journal Article] Gender-Specific Associations of Perceived Stress and Coping Strategies with C-Reactive Protein in Middle-Aged and Older Men and Women.2014

    • Author(s)
      Shimanoe C, Otsuka Y, Hara M, Nanri H, Nishida Y, Nakamura K, Higaki Y, Imaizumi T, Taguchi N, Sakamoto T, Horita M, Shinchi K, Tanaka K
    • Journal Title

      International journal of behavioral medicine

      Volume: 未定

    • DOI

      10.1007/s12529-013-9341-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460759, KAKENHI-PROJECT-25870517, KAKENHI-PROJECT-221S0001
  • [Journal Article] Asbestos-related mesothelioma : Prevention, early detection, treatment2014

    • Author(s)
      Imai, M. and Hino O.
    • Journal Title

      JSM Clinical Oncology and Research

      Volume: 2 Issue: 3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] がんエピゲノム異常を理解し、応用し、そして制御するために2014

    • Author(s)
      鈴木拓,今井浩三
    • Journal Title

      実験医学

      Volume: 32 Pages: 3024-3029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Journal Article] Overview and Future prospect of “Promotion plan for the platform of human resource development for cancer”2014

    • Author(s)
      Imai K.
    • Journal Title

      Juntendo Medical Journal

      Volume: 60(3) Pages: 234-237

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Journal Article] Significance of the progesterone receptor and epidermal growth factor receptor, but not the estrogen receptor, in chemically induced lung carcinogenesis in female A/J mice2014

    • Author(s)
      Kishi S, Yokohira M, Yamakawa K, Saoo K, Imaida K
    • Journal Title

      Oncol. Lett

      Volume: 8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions2014

    • Author(s)
      Naito T, Nosho K, Ito M, Igarashi H, Mitsuhashi K, Yoshii S, Aoki H, Nomura M, Sukawa Y, Yamamoto E, Adachi Y, Takahashi H, Hosokawa M, Fujita M, Takenouchi T, Maruyama R, Suzuki H, Baba Y, Imai K, Yamamoto H, Ogino S, Shinomura Y.
    • Journal Title

      World J Gastroenterol

      Volume: 20(29) Issue: 29 Pages: 10050-61

    • DOI

      10.3748/wjg.v20.i29.10050

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
  • [Journal Article] 大規模コホートを用いた大腸癌のノンコーディングRNA発現異常と生活習慣の分子疫学的解析2014

    • Author(s)
      能正勝彦,五十嵐央祥,伊藤美樹,三橋 慧,栗原弘義,菅野伸一,内藤崇史,須河安恭敬,松永康孝,足立 靖,野島正寛,今井浩三,丸山玲緒,鈴木 拓,山本博幸,篠村恭久.
    • Journal Title

      日本癌病態治療研究会誌

      Volume: 20(1) Pages: 60-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Journal Article] Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk2013

    • Author(s)
      Suzuki R, Yamamoto E, Nojima M, Maruyama R, Yamano HO, Yoshikawa K, Kimura T, Harada T, Ashida M, Niinuma T, Sato A, Nosho K, Yamamoto H, Kai M, Sugai T, Imai K, Suzuki H, Shinomura Y
    • Journal Title

      J Gastroenterol

      Volume: (Epub ahead of print)

    • Data Source
      KAKENHI-PROJECT-24650632
  • [Journal Article] Characteristics of Japanese inflammatory bowel disease susceptibility loci2013

    • Author(s)
      Arimura Y, Isshiki H, Onodera K, Nagaishi K, Yamashita K, Sonoda T, Matsumoto T, Takahashi A, Takazoe M, Yamazaki K, Kubo M, Fujimiya M, Imai K, Shinomura Y
    • Journal Title

      J Gastroenterol Aug 13

      Volume: Epub ahead of print

    • Data Source
      KAKENHI-PROJECT-24650632
  • [Journal Article] Gender-dependent effects of gonadectomy on lung carcinogenesis by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in female and male A/J mice.2013

    • Author(s)
      Ninomiya F., Yokohira M., Kishi S., Nakano Y., Yamakawa K., Inoue T., Kuno T., Imaida K.
    • Journal Title

      Oncol Rep

      Volume: 30 Pages: 2632-2638

    • DOI

      10.3892/or.2013.2759

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk.2013

    • Author(s)
      Suzuki R, Yamamoto E, Nojima M, Maruyama R, Yamano HO, Yoshikawa K, Kimura T, Harada T, Ashida M, Niinuma T, Sato A, Nosho K, Yamamoto H, Kai M, Sugai T, Imai K, Suzuki H, Shinomura Y.
    • Journal Title

      J Gastroenterol

      Volume: Epub ahead of print

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24650632
  • [Journal Article] Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk.2013

    • Author(s)
      Suzuki R, Yamamoto E, Nojima M, Maruyama R, Yamano HO, Yoshikawa K, Kimura T, Harada T, Ashida M, Niinuma T, Sato A, Nosho K, Yamamoto H, Kai M, Sugai T, Imai K, Suzuki H, Shinomura Y.
    • Journal Title

      J Gastroenterol

      Volume: Epub ahead of print

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129
  • [Journal Article] Mode of action of ethyl tertiary-butyl ether hepatotumorigenicity in the rat: Evidence for a role of oxidative stress via activation of CAR, PXR and PPAR signaling pathways.2013

    • Author(s)
      Kakehashi A,Wei M(9人中7番目), et al
    • Journal Title

      Toxicol Appl Pharmacol

      Volume: 273(2) Pages: 390-400

    • DOI

      10.1016/j.taap.2013.09.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23501323, KAKENHI-PROJECT-25462499, KAKENHI-PROJECT-221S0001
  • [Journal Article] Possible involvement of Wnt11 in colorectal cancer progression.2013

    • Author(s)
      ishioka M, Ueno K, Hazama S, et al
    • Journal Title

      Mol Carcinog

      Volume: 10 Pages: 207-17

    • DOI

      10.1002/mc.21845

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591725, KAKENHI-PROJECT-23240129
  • [Journal Article] Characteristics of Japanese inflammatory bowel disease susceptibility loci.2013

    • Author(s)
      Arimura Y, Isshiki H, Onodera K, Nagaishi K, Yamashita K, Sonoda T, Matsumoto T, Takahashi A, Takazoe M, Yamazaki K, Kubo M, Fujimiya M, Imai K, Shinomura Y.
    • Journal Title

      J Gastroenterol

      Volume: Epub ahead of print

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129
  • [Journal Article] Human Tcell leukemia virus type 2 (HTLV-2)Tax2 has a dominant activity over HTLV-1 Tax1 to immortalize human CD4+ T cells2013

    • Author(s)
      Michitaka Imai
    • Journal Title

      Virus Genes.

      Volume: 46 Pages: 39-46

    • DOI

      10.1007/s11262-012-0831-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590537, KAKENHI-PROJECT-23591376, KAKENHI-PROJECT-23659395, KAKENHI-PROJECT-23790436, KAKENHI-PROJECT-23790498, KAKENHI-PROJECT-221S0001
  • [Journal Article] Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk.2013

    • Author(s)
      Suzuki R, Yamamoto E, Nojima M, Maruyama R, Yamano HO, Yoshikawa K, Kimura T, Harada T, Ashida M, Niinuma T, Sato A, Nosho K, Yamamoto H, Kai M, Sugai T, Imai K, Suzuki H, Shinomura Y.
    • Journal Title

      J Gastroenterol

      Volume: [Epub ahead of print]

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Cancer detection by ubiquitin carboxyl-terminal esterase L1 methylation in pancreatobiliary fluids.2013

    • Author(s)
      Kato N, Yamamoto H, Adachi Y, Ohashi H, Taniguchi H, Suzuki H, Nakazawa M, Kaneto H, Sasaki S, Imai K, Shinomura Y
    • Journal Title

      World Journal of Gastroenterology

      Volume: 19(11) Pages: 1718-1727

    • DOI

      10.3748/wjg.v19.i11.1718

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23659400, KAKENHI-PROJECT-24650632
  • [Journal Article] Characteristics of Japanese inflammatory bowel disease susceptibility loci2013

    • Author(s)
      Arimura Y, Isshiki H, Onodera K, Nagaishi K, Yamashita K, Sonoda T, Matsumoto T, Takahashi A, Takazoe M, Yamazaki K, Kubo M, Fujimiya M, Imai K, Shinomura Y
    • Journal Title

      J Gastroenterol

      Volume: (Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129
  • [Journal Article] Association between genomic alterations and metastatic behavior of colorectal cancer identified by array-based comparative genomic hybridization2013

    • Author(s)
      Sawada T, Yamamoto E, Suzuki H
    • Journal Title

      Genes Chromosomes Cancer.

      Volume: 52(2) Pages: 140-149

    • DOI

      10.1002/gcc.22013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590317, KAKENHI-PROJECT-22790655, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23300366, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-24650632, KAKENHI-PROJECT-25460420, KAKENHI-PROJECT-221S0001
  • [Journal Article] Strain differences in pleural mesothelial cell reactions induced by potassium octatitanate fibers (TISMO) infused directly into the thoracic cavity.2013

    • Author(s)
      Yokohira M., Nakano Y., Yamakawa K., Kishi S., Ninomiya F., Saoo K., Imaida K.
    • Journal Title

      Exp. Toxicol. Pathol.

      Volume: 65(6) Pages: 925-932

    • DOI

      10.1016/j.etp.2013.01.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Report of the Japan Diabetes Society/Japanese Cancer Association joint committee on diabetes and cancer.2013

    • Author(s)
      Kasuga M, Ueki K, Tajima N, Noda M, Ohashi K, Noto H, Goto A, Ogawa W, Sakai R, Tsugane S, Hamajima N, Nakagama H, Tajima K, Miyazono K, Imai K.
    • Journal Title

      Cancer Sci

      Volume: 104(7) Pages: 965-976

    • DOI

      10.1111/cas.12203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Methylation of a panel of microRNA genes is a novel biomarker for detection of bladder cancer.2013

    • Author(s)
      Shimizu T, Suzuki H, Nojima M, Kitamura H, Yamamoto E, Maruyama R, Ashida M, Hatahira T, Kai M, Masumori N, Tokino T, Imai K, Tsukamoto T, Toyota M
    • Journal Title

      European Urology

      Volume: 63 Pages: 91-100

    • DOI

      10.1016/j.eururo.2012.11.030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23659658, KAKENHI-PROJECT-24650632, KAKENHI-PUBLICLY-25134715, KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-221S0001
  • [Journal Article] Characteristics of Japanese inflammatory bowel disease susceptibility loci.2013

    • Author(s)
      Arimura Y, Isshiki H, Onodera K, Nagaishi K, Yamashita K, Sonoda T, Matsumoto T, Takahashi A, Takazoe M, Yamazaki K, Kubo M, Fujimiya M, Imai K, Shinomura Y.
    • Journal Title

      J Gastroenterol

      Volume: Epub ahead of print

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24650632
  • [Journal Article] Upregulation of miR-196α and HOTAIR drive malignant character in gastrointestinal stromal tumors2012

    • Author(s)
      Takeshi Niinuma
    • Journal Title

      Cancer Research

      Volume: 72 Pages: 1126-1136

    • DOI

      10.1158/0008-5472.can-11-1803

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790655, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23300366, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23659400, KAKENHI-PROJECT-23659658, KAKENHI-PROJECT-24650632
  • [Journal Article] Emerging links between epigenetic alterations and dysregulation of noncoding RNAs in cancer.2012

    • Author(s)
      Maruyama R, Suzuki H, Yamamoto E, Imai K, Shinomura Y
    • Journal Title

      Tumor Biol

      Volume: 33 Pages: 277-285

    • DOI

      10.1007/s13277-011-0308-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-24650632
  • [Journal Article] Toxicity of Nicotine by Repeated Intratracheal Instillation to F344 Rats2012

    • Author(s)
      Yokohira M, Nakano Y, Hashimoto N, Yamakawa K, Ninomiya F, Kishi S, Saoo K, Imaida K.
    • Journal Title

      J Toxicol Pathol

      Volume: 25 Issue: 4 Pages: 257-263

    • DOI

      10.1293/tox.25.257

    • NAID

      130002499152

    • ISSN
      0914-9198, 1881-915X
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Non-invasive X-ray micro-computed tomographic evaluation of indomethacin on urethane- induced lung carcinogenesis in mice.2012

    • Author(s)
      Ueno T, Imaida K, Yoshimoto M, Hayakawa T, Takahashi M, Imai T, Yanaka A, Tsuta K, Komiya M, Wakabayashi K and Mutoh M.
    • Journal Title

      Anticancer Res

      Volume: 32(11) Pages: 4773-80

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Silencing of KLF2 by the EZH2 in human cancer2012

    • Author(s)
      Taniguchi H, Jacinto F.V., Villanueva A, Fernandez AF, Yamamoto H, Carmona F.J, Puertas S, Marquez VE, Shinomura Y, Imai K, and Esteller M
    • Journal Title

      Oncogene

      Volume: 31 Pages: 1988-1994

    • DOI

      10.1038/onc.2011.387

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23701063, KAKENHI-PROJECT-24650632
  • [Journal Article] Molecular dissection of premalignant colorectal lesions reveals early onset of CpG island methylator phenotype2012

    • Author(s)
      Yamamoto E, Suzuki H, Yamano HO
    • Journal Title

      American Journal of Pathology

      Volume: 181(5) Pages: 1847-1861

    • DOI

      10.1016/j.ajpath.2012.08.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590317, KAKENHI-PROJECT-22790655, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658, KAKENHI-PROJECT-23791283, KAKENHI-PROJECT-24650632
  • [Journal Article] Genome-wide profiling of chromatin signatures reveals epigenetic regulation of microRNA genes in colorectal cancer.2012

    • Author(s)
      Suzuki H
    • Journal Title

      Cancer Research

      Volume: 71 Pages: 5646-5658

    • DOI

      10.1158/0008-5472.can-11-1076

    • NAID

      130004436468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300320, KAKENHI-PROJECT-22790655, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658
  • [Journal Article] Role of acyclic retinoid in the chemoprevention of hepatocellular carcinoma: basic aspects, clinical applications, and future prospects.2012

    • Author(s)
      Shimizu M, Imai K, Takai K, Moriwaki H.
    • Journal Title

      Curr Cancer Drug Targets

      Volume: 12 Pages: 1119-28

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Model of translational cancer research in multiple myeloma.2012

    • Author(s)
      Yasui H, Ishida T, Maruyama R, Nojima M, Ikeda H, Suzuki H, Hayashi T, Shinomura Y, Imai K.
    • Journal Title

      Cancer Sci

      Volume: 103 Pages: 1207-1212

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Epigenetic alteration of DNA in mucosal wash fluid predicts invasiveness of colorectal tumors.2012

    • Author(s)
      Seiko Kamimae
    • Journal Title

      Cancer Prev Res(Phila)

      Volume: 4 Pages: 674-683

    • DOI

      10.1158/1940-6207.capr-10-0214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790655, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658
  • [Journal Article] Insulin-like growth factor receptor expression is associated with aggressive phenotypes and has therapeutic activity in biliary tract cancers2012

    • Author(s)
      Ohashi H
    • Journal Title

      Cancer Sci

      Volume: 103 Pages: 252-261

    • DOI

      10.1111/j.1349-7006.2011.02138.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590703, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23659401, KAKENHI-PROJECT-23701063
  • [Journal Article] Lung tumorigenesis promoted by anti-apoptotic effects of cotinine, a nicotine metabolite through activation of PI3K/Akt pathway2012

    • Author(s)
      Nakada T, et al.
    • Journal Title

      J. Toxicol. Sci.

      Volume: 37 Issue: 3 Pages: 555-563

    • DOI

      10.2131/jts.37.555

    • NAID

      130004446976

    • ISSN
      0388-1350, 1880-3989
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24501342, KAKENHI-PROJECT-221S0001
  • [Journal Article] Upregulation of miR-196a and HOTAIR drive malignant character in gastrointestinal stromal tumors.2012

    • Author(s)
      Niinuma T, Suzuki H, Nojima M, Imai K et al.
    • Journal Title

      Cancer Res

      Volume: 72(5) Pages: 1126-1136

    • NAID

      10031131121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Model of translational cancer research in multiple myeloma.2012

    • Author(s)
      Yasui H, Ishida T, Maruyama R, Nojima M, Ikeda H, Suzuki H, Hayashi T, Shinomura Y, Imai K
    • Journal Title

      Cancer Sci.

      Volume: 103 Pages: 1907-1912

    • DOI

      10.1111/j.1349-7006.2012.02384.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23591399, KAKENHI-PROJECT-24650632
  • [Journal Article] Genome-wide analysis of DNA methylation identifies novel cancer-related genes in hepatocellular carcinoma2012

    • Author(s)
      Shitani M, Sasaki S, Akutsu N, Takagi H, Suzuki H, Nojima M, Yamamoto H, Tokino T, Hirata K, Imai K, Toyota M, Shinomura Y
    • Journal Title

      Tumor Biol

      Volume: 33 Pages: 1307-1317

    • DOI

      10.1007/s13277-012-0378-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23659658
  • [Journal Article] A novel pit pattern identifies the precursor of colorectal cancer derived from sessile serrated adenoma2012

    • Author(s)
      Kimura T, Yamamoto E, Yamano HO.
    • Journal Title

      Am J Gastroenterol

      Volume: 107(3) Pages: 460-469

    • DOI

      10.1038/ajg.2011.457

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590317, KAKENHI-PROJECT-22790655, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23501261
  • [Journal Article] Aberrant methylation of RASGRF1 is associated with an epigenetic field defect and increased risk of gastric cancer2012

    • Author(s)
      Takamaru H, Yamamoto E, Suzuki H.
    • Journal Title

      Cancer Prev Ther (Phila)

      Volume: 5(10) Pages: 1203-12

    • DOI

      10.1158/1940-6207.capr-12-0056

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590317, KAKENHI-PROJECT-22790655, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23300366, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23659400, KAKENHI-PROJECT-23659658, KAKENHI-PROJECT-24650632
  • [Journal Article] Interferon-α/βand anti-fibroblast growth factor receptor 1 monoclonal antibody suppress hepatic cancer cells in vitro and in vivo2011

    • Author(s)
      Sasaki S., et al
    • Journal Title

      PLoS ONE

      Volume: 6

    • DOI

      10.1371/journal.pone.0019618

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590853, KAKENHI-PROJECT-22790917, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23591399
  • [Journal Article] Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis.2011

    • Author(s)
      Hizaki K, Yamamoto H, Taniguchi H, Adachi Y, Nakazawa M, Tanuma T, Kato N, Sukawa Y, Sanchez JV, Suzuki H, Sasaki S, Imai K, Shinomura Y
    • Journal Title

      Modern Pathology

      Volume: 24 Pages: 876-884

    • DOI

      10.1038/modpathol.2011.10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23300366, KAKENHI-PROJECT-23390200, KAKENHI-PROJECT-23659400
  • [Journal Article] Co-expression of laminin β3 and γ2 chains and epigenetic inactivation of laminin α3 chain in gastric cancer2011

    • Author(s)
      Ii M, Yamamoto H, Taniguchi H, Adachi Y, Nakazawa M, Ohashi H, Tanuma T, Sukawa Y, Suzuki H, Sasaki S, Imai K, Shinomura Y
    • Journal Title

      Int J Oncol

      Volume: 39 Pages: 593-599

    • Data Source
      KAKENHI-PROJECT-23240129
  • [Journal Article] The efficacy of IGF-I receptor monoclonal antibody against human gastrointestinal carcinomas is independent of k-ras mutation status.2011

    • Author(s)
      Ii M, Li H, Adachi Y, Yamamoto H, Ohashi H, Taniguchi H, Arimura Y, Carbone DP, Imai K, Shinomura Y
    • Journal Title

      Clin Cancer Res

      Volume: 17 Pages: 5048-5059

    • DOI

      10.1158/1078-0432.ccr-10-3131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23240129
  • [Journal Article] Interferon-α/βand anti-fibroblast growth factor receptor 1 monoclonal antibody suppress hepatic cancer cells in vitro and in vivo2011

    • Author(s)
      Sasaki S, Ishida T, Toyota M, Ota A, Suzuki H, Takaoka A, Yasui H, Yamamoto H, Takagi H, Maeda M, Seito T, Tsujisaki M, Shinomura Y, Imai K
    • Journal Title

      PLoS One

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590853
  • [Journal Article] Instulin resistance raises the risk for recurrence of stage I hepatocellular carcinoma after curative radiofrequency ablation in hepatitis C virus-positive patients : A prospective, case series study2010

    • Author(s)
      Imai, K., et al
    • Journal Title

      Hepatol Res

      Volume: 40 Pages: 376-382

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] IGFBP7 is p53 responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype.2010

    • Author(s)
      Suzuki H, Igarashi S, Nojima M, Maruyama R, Yamamoto E, Kai M, Akashi H, Watanabe Y, Yamamoto H, Sasaki Y, Itoh F, Imai K, Sugai T, Shen L, Issa JPJ, Shinomura Y, Tokino T, Toyota M
    • Journal Title

      Carcinogenesis 31

      Pages: 342-349

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype.2010

    • Author(s)
      Suzuki H, Igarashi S, Nojima M, Maruyama R, Yamamoto E, Kai M, Akashi H, Watanabe Y, Yamamoto H, Sasaki Y, Itoh F, Imai K, Sugai T, Shen L, Issa JP, Shinomura Y, Tokino T, Toyota M
    • Journal Title

      Carcinogenesis Vol.31

      Pages: 342-349

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016060
  • [Journal Article] p53 family members regulate the expression of the apolipoprotein D gene.2009

    • Author(s)
      Sasaki Y, Negishi H, Koyama R, Anbo N, Ohori K, Idogawa M, Mita H, Toyota M, Imai K, Shinomura Y, Tokino T
    • Journal Title

      J Biol Chem 284

      Pages: 872-883

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Preventing oxidative stress: A new role for XBP12009

    • Author(s)
      Liu Y, Adachi M, Zhao S, Hareyama M, Koong AC, Luo D, Rando TA, Imai K and Shinomura Y
    • Journal Title

      Cell Death Diff (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590566
  • [Journal Article] Genomic Screening for Genes Silenced by DNA Methylation Revealed an Association between RASD1 Inactivation and Dexamethasone Resistance in Multiple Myeloma.2009

    • Author(s)
      Nojima M, Maruyama R, Yasui H, Suzuki H, Maruyama Y, Tarasawa I, Sasaki Y, Asaoku H, Sakai H, Hayashi T, Mori M, Imai K, Tokino T, Ishida T, Toyota M, Shinomura Y
    • Journal Title

      Clin Cancer Res 15

      Pages: 4356-4364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Epigenetic inactivation of the circadian clock gene BMAL1 in hematologic malignancies.2009

    • Author(s)
      Taniguchi H, Fernandez AF, Setien F, Ropero S, Ballestar E, Villanueva A, Yamamoto H, Imai K, Shinomura Y, Esteller M
    • Journal Title

      Cancer Res Vol.69

      Pages: 8447-8454

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016060
  • [Journal Article] Integrated analysis of genetic and epigenetic alterations in cancer.2009

    • Author(s)
      Toyota M, Suzuki H, Yamamoto E, Yamano H, Imai K, Shinomura Y
    • Journal Title

      Epigenomics 1

      Pages: 291-299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Cancer Epigenomics : Implications of DNA methylation in personalized therapy.2009

    • Author(s)
      Toyota M, Suzuki H, Yamashita T, Hirata K, Shinomura Y, Tokino T, Imai K
    • Journal Title

      Cancer Sci 100

      Pages: 787-791

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] A single recombinant adenovirus expressing p53 and p21-targeting artificial microRNAs efficiently induces apoptosis in human cancer cells.2009

    • Author(s)
      Idogawa M, Sasaki Y, Suzuki H, Mita H, Imai K, Shinomura Y, Tokino T
    • Journal Title

      Clin Cancer Res Vol.15

      Pages: 3725-3732

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016060
  • [Journal Article] Epigenetic inactivation of the circadian clock gene BMAL1 in hematological malignancies.2009

    • Author(s)
      Taniguchi H, Fernandez AF, Setien F, Ropero S, Ballestar E, Villanueva A, Yamamoto H, Imai K, Shinomura Y, Esteller M
    • Journal Title

      Cancer Res 69

      Pages: 8447-8454

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] A requirement for DICER to maintain full promoter CpG Island hypermethylation in human cancer cells.2008

    • Author(s)
      Ting A, Suzuki H, Cope L, Schuebel K, Lee B, Toyota M, Imai K, Shinomura Y, Tokino T, Baylin SB
    • Journal Title

      Cancer Res 68

      Pages: 2570-2575

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer.2008

    • Author(s)
      Maruyama R, Akino K, Toyota M, Suzuki H, Imai T, Ohe-Toyota M, Yamamoto E, Nojima M, Fujikane T, Sasaki Y, Yamashita T, Watanabe Y, Hiratsuka Y, Hirata K, Itoh F, Imai K, Shinomura Y, Tokino T
    • Journal Title

      Carcinogenesis 29

      Pages: 1312-1318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma.2008

    • Author(s)
      Imai T, Toyota M, Suzuki H, Akino K, Ogi K, Sogabe Y, Kashima L, Maruyama R, Nojima M, Mita H, Sasaki Y, Itoh F, Imai K, Shinomura Y, Hiratsuka H, Tokino T
    • Journal Title

      Cancer Sci 99

      Pages: 958-966

    • NAID

      10024006089

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] DNA methylation and cancer pathways in gastrointestinal tumors.2008

    • Author(s)
      Suzuki H, Tokino T, Shinomura Y, Imai K, Toyota M
    • Journal Title

      Pharmacogenomics 9

      Pages: 1917-1928

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Carcinogenesis and microsatellite instability: the interrelationship between genetics and epigenetics.2008

    • Author(s)
      Imai K, Yamamoto H
    • Journal Title

      Carcinogenesis Vol.29

      Pages: 673-680

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016060
  • [Journal Article] Carcinogenesis and microsatellite instability : the interrelationship between genetics and epigenetics.2008

    • Author(s)
      Imai K., et al.
    • Journal Title

      Carcinogenesis 29

      Pages: 673-680

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Epigenetic silencing of microRNA-34b/c and BTG4 is associated with CpG island methylation in colorectal cancer.2008

    • Author(s)
      Toyota M, Suzuki H, Sasaki Y, Maruyama R, Imai K, Shinomura Y, Tokino T
    • Journal Title

      Cancer Res 68

      Pages: 4123-4132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma.2008

    • Author(s)
      Takagi H, Sasaki S, Suzuki H, Toyota M, Maruyama R, Nojima M, Yamamoto H, Omata M, Tokino T, Imai K, Shinomura Y
    • Journal Title

      J. Gastroenterol 43

      Pages: 378-389

    • NAID

      10021268741

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Carcinogenesis and microsatellite instability:the interrelationship between genetics and epigenetics2008

    • Author(s)
      Imai K
    • Journal Title

      Carcinogenesis 29

      Pages: 673-680

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016060
  • [Journal Article] Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer.2008

    • Author(s)
      Maruyama R, Akino K, Toyota M, Suzuki H, Imai T, Ohe-Toyota M, Yamamoto E, Nojima M, Fujikane T, Sasaki Y, Yamashita T, Watanabe Y, Hiratsuka H, Hirata K, Itoh F, Imai K, Shinomura Y, Tokino T
    • Journal Title

      Carcinogenesis Vol.29

      Pages: 1312-1318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016060
  • [Journal Article] DNA hypermethylation contributes incomplete synthesis of carbohydrate determinants in gastrointestinal cancer.2008

    • Author(s)
      Kawamura YI, Toyota M, Kawashima R, Hagiwara T, Suzuki H, Imai K, Shinomura Y, Tokino T, Kannagi R, Dohi T
    • Journal Title

      Gastroenterol 135

      Pages: 142-151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Identification of flotillin-2, a major protein on lipid rafths, as a novel target of the p53 family members.2008

    • Author(s)
      Sasaki Y, Ohshima Y, Koyama R, Maruyama R, Akashi H, Mita H, Toyota M, Shinomura Y, Imai K, Tokino T
    • Journal Title

      Mol Cancer Res 6

      Pages: 395-406

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer.2008

    • Author(s)
      Suzuki H, Toyota M, Caraway H, Gabrielson E, Ohmura T, Fujikane T, Nishikawa N, Sogabe Y, Nojima M, Sonoda T, Mori M, Hirata K, Imai K, Shinomura Y, Baylin SB, Tokino T
    • Journal Title

      British J Cancer 98

      Pages: 1147-1156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma.2008

    • Author(s)
      Imai T, et. al.
    • Journal Title

      Cancer Sci 99(In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] DNA hypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer.2008

    • Author(s)
      Kawamura YI, Toyota M, Kawashima R, Hagiwara T, Suzuki H, Imai K, Shinomura Y, Tokino T, Kannagi R, Dohi T
    • Journal Title

      Gastroenterology Vol.135

      Pages: 142-151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016060
  • [Journal Article] Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma.2008

    • Author(s)
      Imai T., et al.
    • Journal Title

      Cancer Sci. 99

      Pages: 958-966

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer.2008

    • Author(s)
      Toyota M, Suzuki H, Sasaki Y, Maruyama R, Imai K, Shinomura Y, Tokino T
    • Journal Title

      Cancer Res Vol.68

      Pages: 4123-4132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016060
  • [Journal Article] LINE-1 hypomethylation is associated with increased CpG island methylation in helicobactor pylori-related enlarged fold gastritis.2008

    • Author(s)
      Yamamoto E, Toyota M, Suzuki H, Kondo Y, Imai K, Sanomura T, Murayama Y, Ohe-Toyota M, Maruyama R, Nojima M, Ashida M, Fujii K, Sasaki Y, Hayashi N, Mori M, Imai K, Tokino T, Shinomura Y
    • Journal Title

      Cancer Epidemiol Biomarkers Prev 17

      Pages: 2555-2564

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Novel molecular-targeted therapeutics for the treatment of cancer.2008

    • Author(s)
      Yasui H, Imai K
    • Journal Title

      Anticancer Agents Med Chem Vol.8

      Pages: 470-480

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016060
  • [Journal Article] Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma2008

    • Author(s)
      Imai T
    • Journal Title

      Cancer Sci 99

      Pages: 958-966

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016060
  • [Journal Article] The hsitone deacetylase inhibitor FK288 enhances adenovirus-mediated p53 family gene therapy in cancer models.2008

    • Author(s)
      Sasaki Y, Negishi H, Idogawa M, Suzuki H, Mita H, Toyota M, Shinomura Y, Imai K, Tokino T
    • Journal Title

      Mol Cancer Ther 7

      Pages: 779-787

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Nonsteroidal anti-inflammatory drugs and oxidative stress in cancer cells.2007

    • Author(s)
      Adachi M, Sakamoto H, Kawamura R, Wang W, Imai K, Shinomura Y.
    • Journal Title

      Histol Histopathol. 22

      Pages: 437-442

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590273
  • [Journal Article] Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer.2007

    • Author(s)
      Nojima M, Suzuki H, Toyota M, Watanabe Y, Maruyama R, Sasaki S, Sasaki Y, Mita H, Nishikawa N, Yamaguchi K, Hirata K, Itoh F, Tokino T, Mori M, Imai K, Shinomura Y
    • Journal Title

      Oncogene 26

      Pages: 4699-4713

    • NAID

      130004927598

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors.2007

    • Author(s)
      Sato H, Suzuki H, Toyota M, Nojima M, Maruyama R, Sasaki S, Takagi H, Sogabe Y, Sasaki Y, Idogawa M, Sonoda T, Mori M, Imai K, Tokino T, Shinomura Y
    • Journal Title

      Carcinogenesis 28

      Pages: 2459-2466

    • NAID

      130004436413

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Gene amplification and overexpression of PRDM14 in breast cancer2007

    • Author(s)
      Nishikawa N, Toyota M, Suzuki H, Homma T, Fujikane T, Ohmura T, Nishidate T, Ohe-Toyota M, Maruyama R, Sonoda T, Sasaki Y, Urano T, Imai K, Hirata K, Tokino T
    • Journal Title

      Cancer Res 67

      Pages: 9649-9657

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Nonsteroidal anti-inflammatory drugs and oxidative stress in cancer cells2007

    • Author(s)
      Adachi M, Sakamoto H, Kawamura R, Wang W, Imai K, Shinomura Y
    • Journal Title

      Histol Histopathol 22

      Pages: 437-442

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590566
  • [Journal Article] Transcriptional silencing of hedgehog-interacting protein by CpG hypermethylation and chromatic structure in human gastrointestinal cancer.2007

    • Author(s)
      Taniguchi H, Yamamoto H, Akutsu N, Nosho K, Adachi Y, Imai K, Shinomura Y
    • Journal Title

      J Pathol Vol.213

      Pages: 131-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016060
  • [Journal Article] Comparing the DNA hypermethylation with gene mutations in human colorectal cancer.2007

    • Author(s)
      Schuebel KE, Chen E, Cope Lm Glockner SC, Suzuki H, Yi JM, Chan TA, Van Neste L, Van Criekinge W, van den Bosch S, van Engeland M, Ting AH, Jair K, Yu W, Toyota M, Imai K, Ahuja N, Herman JG, Baylin SB
    • Journal Title

      Plos Genet 3

      Pages: 1709-1723

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Expression profiling of PRDM family genes identified PRDM5 as a target of epigenetic silencing in colorectal and gastric cancer.2007

    • Author(s)
      Watanabe Y, Toyota M, Kondo Y, Suzuki H, Imai T, Ohe-Toyota M, Maruyama R, Nojima M, Sasaki Y, Sekido Y, Hiratsuka H, Shinomura Y, Imai K, Itoh F, Tokino T
    • Journal Title

      Clin Cancer Res 13

      Pages: 4786-4794

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer.2007

    • Author(s)
      Nojima M, Suzuki H, Toyota M, Watanabe Y, Maruyama R, Sasaki S, Sasaki Y, Mita H, Nishikawa N, Yamaguchi K, Hirata K, Itoh F, Tokino T, Mori M, Imai K, Shinomura Y
    • Journal Title

      Oncogene Vol.26

      Pages: 4699-4713

    • NAID

      130004927598

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016060
  • [Journal Article] Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer.2007

    • Author(s)
      Akino K, Toyota M, Suzuki H, Imai T, Maruyama R, Kusano M, Nishikawa N, Watanabe Y, Sasaki Y, Abe T, Yamamoto E, Tarasawa I, Sonoda T, Mori M, Imai K, Shinomura Y, Tokino T
    • Journal Title

      Cancer Sci 98

      Pages: 88-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Comparative genome analysis identifies the vitamin D receptor gene as a direct target of p53-mediated transcriptional activation.2006

    • Author(s)
      Maruyama R, Aoki F, Toyota M, Sasaki Y, Akashi H, Mita H, Suzuki H, Akino K, Ohe-Toyota M, Maruyama Y, Tatsumi H, Imai K, Shinomura Y, Tokino T
    • Journal Title

      Cancer Res Vol.66

      Pages: 4574-4583

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016060
  • [Journal Article] Histone deacetylase inhibitors enhance phosphorylation of histone H2AX after ionizing radiation.2006

    • Author(s)
      Zhang Y, Adachi M, Zou H, Hareyama M, Imai K, Shinomura Y.
    • Journal Title

      Int J Radiat Oncol Biol Phys 65

      Pages: 859-866

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590273
  • [Journal Article] Bmf is a possible mediator in histone deacetylase inhibitors FK228 and CBHA-induced apoptosis.2006

    • Author(s)
      Zhang YB, Adachi M, Kawamura R, Imai K.
    • Journal Title

      Cell Death and Differ. 133

      Pages: 129-240

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590273
  • [Journal Article] Comparing antibody and small-molecule therapies for cancer.2006

    • Author(s)
      Imai, K., et al.
    • Journal Title

      Nature Rev Cancer 6(9)

      Pages: 714-727

    • Data Source
      KAKENHI-PROJECT-16062101
  • [Journal Article] Comparing antibody and small-molecule therapies for cancer.2006

    • Author(s)
      Imai K, Takaoka A
    • Journal Title

      Nat Rev Cancer 6・9

      Pages: 714-727

    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Parthenolide-induced apoptosis in multiple myeloma cells involves reactive oxygen species generation and cell sensitivity depends on catalase activity.2006

    • Author(s)
      Wang W, Adachi M, Kawamura R, Sakamoto H, Hayashi T, Ishida T, Imai K, Shinomura Y.
    • Journal Title

      Apoptosis 11

      Pages: 2225-2235

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590273
  • [Journal Article] Comparative genome analysis identified the vitamin D receptor gene as a direct target of p53-mediated transcriptional activation.2006

    • Author(s)
      Maruyama R, Aoki F, Toyota M, Sasaki Y, Akashi H, Mita H, Suzuki H, Akino K, Ohe-Toyota M, Maruyama Y, Tatsumi H, Imai K, Shinomura Y, Tokino T
    • Journal Title

      Cancer Res 66

      Pages: 4574-4583

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Bmf contributes to histone deacetylase inhibitor-mediated enhancing effects on apoptosis after ionizing radiation.2006

    • Author(s)
      Zhang Y, Adachi M, Kawamura R, Zou HC, Imai K, Hareyama M, Shinomura Y.
    • Journal Title

      Apoptosis 11

      Pages: 1349-1357

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590273
  • [Journal Article] 2-Methoxyestradiol, an Endogenous Mammalian Metabolite, Radiosensitizes Colon Carcinoma Cells through c-Jun N- Terminal Kinase Activation.2006

    • Author(s)
      HuiChao Zou, Masaaki Adachi, Kohzoh Imai, Masato Hareyama, Katsuji Yoshioka, Shiguang Zhao, Yasuhisa Shinomura
    • Journal Title

      Clin Cancer Res 12

      Pages: 6532-6539

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590273
  • [Journal Article] Comparing antibody and small-molecule therapies for cancer2006

    • Author(s)
      Imai K
    • Journal Title

      Nat Rev Cancer 6

      Pages: 714-727

    • Data Source
      KAKENHI-PROJECT-17016060
  • [Journal Article] Comparing antibody and small-molecule therapies for cancer.2006

    • Author(s)
      Imai K, Takaoka A
    • Journal Title

      Nat Rev Cancer Vol.6

      Pages: 714-727

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016060
  • [Journal Article] Genetic, epigenetic and clinicopathological features of gastric cancers with CpG island methylator phenotype and an association with Epstein-Barr virus.2006

    • Author(s)
      Kusano M, Toyota M, Suzuki H, Akino K, Aoki F, Fujita M, Hosokawa M, Shinomura Y, Imai K, Tokino T
    • Journal Title

      Cancer 106

      Pages: 1467-1479

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Tumour matrilysin expression predicts metastatic potential of stage I (pT1) colon and rectal cancers.2005

    • Author(s)
      Kurokawa S, Arimura Y, Yamamoto H, Adachi Y, Endo T, Sato T, Suga T, Hosokawa M, Shinomura Y, Imai K
    • Journal Title

      Gut Vol.54

      Pages: 1751-1758

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016060
  • [Journal Article] The RAS effector RASSF2 is a novel tumor suppressor in colorectal cancer.2005

    • Author(s)
      Akino K, Toyota M, Suzuki H, Mita H, Sasaki Y, Ohe-Toyota M, Issa JP, Hinoda Y, Imai K, Tokino T
    • Journal Title

      Gastroenterol 129

      Pages: 156-169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Genetic polymorphism in cytochrome P450 (CYP) 7A1 and risk of colorectal cancer : The Fukuoka Colorectal Cancer Study.2005

    • Author(s)
      Hagiwara, T., Kono.S., Yin, G., Toyomura, K., Hagiwara, T., Nagano, J., Mizoue, T., Mibu, R., Tanaka, M., Kakeji, Y., Maehara, Y., Okamura, T., Ikejiri, K., Futami, K., Yasunami, Y., Maekawa, T., Takenaka, K., Ichimiya, H., Imaizumi, N.
    • Journal Title

      Cancer Res. 65

      Pages: 2979-2982

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Insulin-like growth factor-I receptor blockade anhanceschemotherapy and radiation responses and inhibits tumour growth in human gastric cancer xenografts.2005

    • Author(s)
      Min, Y., Adachi, Y., Yamamoto.H., Imsumran, A., Arimura, Y., Endo, T., Hinoda, Y., Lee, C.-T., Nadaf, S., Carbone, D.P., Imai, K.
    • Journal Title

      Gut 54

      Pages: 591-600

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Nomenclature of dynein light chain-linked BH3-only protein Bim isoforms.2005

    • Author(s)
      Adachi M, Zhao X, Imai K.
    • Journal Title

      Cell Death Differ. 12

      Pages: 192-193

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590273
  • [Journal Article] Relationship between CDX2 gene methylation and dietary factors in gastric cancer patients.2005

    • Author(s)
      Yuasa.Y., Nagasaki, H., Akiyama, Y., Sakai, H., Nakajima, T., Ohkura; Y., Takizawa, T., Koike, M., Tani, M., Iwai, T., Sugihara, K., Imai, K., Nakachi, K.
    • Journal Title

      Carcinogenesis 26

      Pages: 193-200

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Aberrant methylation and silencing of the BNIP3 gene in colorectal and gastric cancer.2005

    • Author(s)
      Murai M, Toyota M, Suzuki H, Satoh A, Akino K, Mita H, Tokino T, Imai K
    • Journal Title

      Clin Cancer Res 11

      Pages: 1021-1027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Sulindac Enhances the Proteasome Inhibitor Bortezomib-Mediated Oxidative Stress and Anticancer Activity.2005

    • Author(s)
      Minami T, Adachi M, Kawamura R, Zhang YB, Shinomura, Y, Imai K.
    • Journal Title

      Clin. Cancer Res. 11

      Pages: 5248-5256

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590273
  • [Journal Article] Adenovirus-mediated gene transfer of caspase-8 sensitizes human adenocarcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand2005

    • Author(s)
      Yasui H, Adachi M, Hamada H, Imai K.
    • Journal Title

      Int J Oncol. 26

      Pages: 537-544

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15603004
  • [Journal Article] Poly(ADP-ribose) polymerase-1 (PARP-1) is a component of the oncogenic T-cell factor-4 (TCF-4)β-catenin complex2005

    • Author(s)
      Idogawa M, Imai K et al.
    • Journal Title

      Gastroenterology 128(In press)

    • Data Source
      KAKENHI-PROJECT-15659238
  • [Journal Article] MUC4 expression is a novel prognostic factor in patients with invasive ductal carcinoma of the pancreas.2005

    • Author(s)
      Saitou, M., Goto, M., Horinouchi, M., Tamada, S., Nagata, K., Hamada, T., Osako, M., Takao, S., Batra, S.K., Aikou, T., Imai.K., Yonezawa.S.
    • Journal Title

      J.Clin.Pathol. 58

      Pages: 845-852

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Poly(ADP-ribose) polymerase-1 (PARP-1) is a component of the oncogenic T-cell factor-4 (TCF-4)/β-catenin complex2005

    • Author(s)
      Idogawa M, Imai K et al.
    • Journal Title

      Gastroenterology 128(In press)

    • Data Source
      KAKENHI-PROJECT-12218234
  • [Journal Article] Adenovirus-mediated gene transfer of caspase-8 sensitizes human adenocarcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand.2005

    • Author(s)
      Yasui H, Adachi M, Hamada H, Imai K.
    • Journal Title

      Int J Oncol. 26

      Pages: 537-544

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590273
  • [Journal Article] Aberrant methylation and silencing of the BNIP3 gene in hematopietic tumors.2005

    • Author(s)
      Murai M, Toyota M, Satoh A, Suzuki H, Akino K, Mita H, Ishida T, Tokino T, Imai K
    • Journal Title

      British J Cancer 92

      Pages: 1165-1172

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Nomenclature of dynein light chain-linked BH3-only protein Bim isoforms2005

    • Author(s)
      Adachi M, Zhao X, Imai K.
    • Journal Title

      Cell Death Differ. 12

      Pages: 192-193

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15603004
  • [Journal Article] Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumors.2005

    • Author(s)
      Alazzouzi, H., Imai, K., et al.
    • Journal Title

      Cancer Res. 65

      Pages: 10170-10173

    • Data Source
      KAKENHI-PROJECT-16062101
  • [Journal Article] Poly(ADP-ribose) polymerase-1 (PARP-1) is a component of the oncogenic T-cell factor-4 (TCF-4)/β-catenin complex2005

    • Author(s)
      Idogawa M, Imai K et al.
    • Journal Title

      Gastroenterology 128(In press)

    • Data Source
      KAKENHI-PROJECT-13854016
  • [Journal Article] Epigenetic inactivation of SFRP's complements genetic alterations to allow constitutive Wnt pathway signaling in human colorectal cancer.2004

    • Author(s)
      Suzuki H, Toyota M, Imai K et al.
    • Journal Title

      Nat.Genet. 36

      Pages: 417-422

    • NAID

      130004436353

    • Data Source
      KAKENHI-PROJECT-13854016
  • [Journal Article] Synergistic effect of histone deacetylase inhibitors FK228 and m-carboxycinnamic acid bis-hydroxamide with proteasome inhibitors PSI and PS-341 against gastrointestinal adenocarcinoma cells.2004

    • Author(s)
      Adachi K, Imai K et al.
    • Journal Title

      Clin Cancer Res. 10

      Pages: 3853-3862

    • Data Source
      KAKENHI-PROJECT-15659238
  • [Journal Article] MUC4 is a novel prognostic factor of intrahepatic cholangiocarcinoma-mass forming type.2004

    • Author(s)
      Shibahara, H., Tamada, S., Higashi, M., Goto, M., Batra, S.K., Hollingsworth, M.A., Imai, K., Yonezawa.S.
    • Journal Title

      Hepatology 39

      Pages: 220-229

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Synergistic effect of histone deacetylase inhibitors FK228 and m-carboxycinnamic acid bis-hydroxamide with proteasome inhibitors PSI and PS-341 against gastrointestinal adenocarcinoma cells.2004

    • Author(s)
      Adachi K, Imai K et al.
    • Journal Title

      Clin Cancer Res. 10

      Pages: 3853-3862

    • Data Source
      KAKENHI-PROJECT-12218234
  • [Journal Article] Expression of ets-related transcriptional factor E1AF is associated with tumor progression and overexpression of matrilysin in human gastric cancer.2004

    • Author(s)
      Yamamoto, H., Horiuchi, S., Adachi, Y., Taniguchi, H., Nosho, K., Min, Y., Imai.K.
    • Journal Title

      Carcinogenesis 25

      Pages: 325-332

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Association of matrilysin-2 (MMP-26) expression with tumor progression and activation of MMP-9 in esophageal squamous cell carcinoma.2004

    • Author(s)
      Yamamoto.H., Vinitketkumnuen, A., Adachi, Y., Taniguchi, H., Hirata, T., Miyamoto, M., Nosho, K., Imsumran, A., Fujita, M., Hosokawa, M., Hinoda, Y., Imai, K.
    • Journal Title

      Carcinogenesis 25

      Pages: 2353-2360

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer.2004

    • Author(s)
      Suzuki, H., Watkins, D.N., Jair, K.-W., Schuebel, K.E., Markowitz, S.D., Chen, W.-D., Pretlow, T.P., Yang, B., AMyama, Y., Engeland, M., Toyota, M., Tokino, T., Hirioda, Y., Imai.K.Herman, J.G., Baylin, S.B.
    • Journal Title

      Nature Genet 36(4)

      Pages: 417-422

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and colorectal cancer : The Fukuoka Colorectal Cancer Study.2004

    • Author(s)
      Yin, G., Kono.S., Toyomura, K., Hagiwara, T., Nagano, J., Mizoue, T., Mibu, R., Tanaka, M., Kakeji, Y., Maehara, Y., Okamura, T., Ikejiri, K., Futami, K., Yasunami, Y., Maekawa, T., Takenaka, K., Ichimiya, H., Imaizumi, N.
    • Journal Title

      Cancer Sci. 95

      Pages: 908-913

    • NAID

      10014197896

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Epigenetic inactivation of class II transactivator (CIITA) is associated with absence of imterferon-γ induced HLA-DR expression in colorectal and gastric cancer cells.2004

    • Author(s)
      Satoh A, Toyota M, Imai K et al.
    • Journal Title

      Oncogene 23

      Pages: 8876-8886

    • Data Source
      KAKENHI-PROJECT-12218234
  • [Journal Article] Synergistic effect of histone deacetylase inhibitors FK228 and m-Carboxycinnamic Acid Bis-Hydroxamide with proteasome inhibitors PSI and PS-341 against gastrointestinal adenocarcinoma cell2004

    • Author(s)
      Adachi M, Zhang YB, Zhao XD, Minami T, Kawamura R, Hinoda Y, Imai K.
    • Journal Title

      Clin. Cancer Res. 10

      Pages: 3853-3862

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15603004
  • [Journal Article] Histone deacetylase inhibitors FK228, N- (2-aminophenyl)-4-[N-(pyridin-3-yl-methoxycarbonyl)aminomethyl] benzamide and M-carboxycinnamic Acid Bis-hydroxamide augment radiation-induced cell death in gastrointestinal adenocarcinoma cells2004

    • Author(s)
      Zhang YB, Adachi M, Zhao X., Kawamura R, Imai K.
    • Journal Title

      Int. J. Cancer 110

      Pages: 301-308

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15603004
  • [Journal Article] Synergistic effect of histone deacetylase inhibitors FK228 and m-carboxycinnamic acid bis-hydroxamide with proteasome inhibitors PSI and PS-341 against gastrointestinal adenocarcinoma cells.2004

    • Author(s)
      Adachi K, Imai K et al.
    • Journal Title

      Clin Cancer Res. 10

      Pages: 3853-3862

    • Data Source
      KAKENHI-PROJECT-13854016
  • [Journal Article] Epigenetic inactivation of SFRP's complements genetic alterations to allow constitutive Wnt pathway signaling in human colorectal cancer.2004

    • Author(s)
      Suzuki H, Toyota M, Imai K et al.
    • Journal Title

      Nat.Genet. 36

      Pages: 417-422

    • NAID

      130004436353

    • Data Source
      KAKENHI-PROJECT-12218234
  • [Journal Article] Perspectives on cancer immuno-epidemiology.2004

    • Author(s)
      Nakachi.K., Hayashi, T., Imai, K., Kusunoki, Y.
    • Journal Title

      Cancer Sci. 95

      Pages: 921-929

    • NAID

      10014260327

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Hofstra RMW. Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLHl methylation status.2004

    • Author(s)
      Oliveira, C, Yamamoto, H., Aaltonen, L.A., Seruca, R., Imai.K.
    • Journal Title

      Hum.Mol.Genet. 13

      Pages: 2303-2311

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Synergistic effect of histone deacetylase inhibitors FK228 and m-carboxycinnamic acid bis-hydroxamide with proteasome inhibitors PSI and PS-341 against gastrointestinal adenocarcinoma cells.2004

    • Author(s)
      Adachi, M., Imai, K.et al.
    • Journal Title

      Clin.Cancer Res. 10

      Pages: 3853-3862

    • Data Source
      KAKENHI-PROJECT-16062101
  • [Journal Article] Epigenetic inactivation of SFRP's complements genetic alterations to allow constitutive Wnt pathway signaling in human colorectal cancer.2004

    • Author(s)
      Suzuki H, Toyota M, Imai K et al.
    • Journal Title

      Nat.Genet. 36

      Pages: 417-422

    • NAID

      130004436353

    • Data Source
      KAKENHI-PROJECT-15659238
  • [Journal Article] Epigenetic inactivation of class II transactivator (CIITA) is associated with absence of interferon-γ induced HLA-DR expression in colorectal and gastric cancer cells.2004

    • Author(s)
      Satoh A, Toyota M, Imai K et al.
    • Journal Title

      Oncogene 23

      Pages: 8876-8886

    • Data Source
      KAKENHI-PROJECT-15659238
  • [Journal Article] Epigenetic inactivation of class II transactivator (CIITA) is associated with absence of interferon-γ induced HLA-DR expression in colorectal and gastric cancer cells.2004

    • Author(s)
      Satoh A, Toyota M, Imai K et al.
    • Journal Title

      Oncogene 23

      Pages: 8876-8886

    • Data Source
      KAKENHI-PROJECT-13854016
  • [Journal Article] Integration of interferon-α/β signalling to p53 responses in tumor suppression and antiviral defence.2003

    • Author(s)
      Takaoka, A., Hayakawa, S., Yanai, H., Stoiber, D., Negishi, H., Kikuchi, H., Sasaki, S., Imai.K., Shibue, T., Honda, K., Taniguchi, T.
    • Journal Title

      Nature 424

      Pages: 516-523

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Mutation of BAD within the BH3 domain impairs its phosphorylation-mediated regulation2003

    • Author(s)
      Adachi M, Zhang YB, Imai K.
    • Journal Title

      FEBS Letters 551

      Pages: 147-152

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15603004
  • [Journal Article] Epigenetic inactivation of CHFR in human tumors.2003

    • Author(s)
      Toyota, M., Sasaki, Y., Satoh, A., Ogi, K., Kikuchi, T., Suzuki, H., Mita, H., Tanaka, N., Itoh, F., Issa, J.P., Jair, K.W., Schuebel, K.E., Tokino, T., Imai.K.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 100

      Pages: 7818-7823

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Detection of anti-Human T-lymphotropic virus type I antibody in whole blood by a novel counting immunoassay.2003

    • Author(s)
      Hinoda, Y., Ikematsu, Y., Horinouchi, M., Sato, S., Yamamoto, K., Nakano, T., Fukui, M., Suehiro, Y., Hamanaka, Y., Nishikawa, Y., Kida, H., Waki, S., Oka, M., Imai, K., Yamaguchi.K., Yonemura, Y., Okabe, H., Takahama, Y., Nagai, S., Yamaguchi, H., Hirai, K.
    • Journal Title

      Clin.Chem. 49

      Pages: 275-280

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Differential involvement of the hypermethylator phenotype in hereditary and sporadic colorectal cancers with high-frequency microsatellite instability.2002

    • Author(s)
      Yamamoto.H, Min, Y., Itoh, F., Imsumran, A., Horiuchi, S., Yoshida, M., Iku, S., Fukushima, H., Imai, K.
    • Journal Title

      Genes Chromosomes Cancer 33

      Pages: 322-325

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Smad-dependent GADD45beta expression mediates delayed activation of p38 MAP kinase by TGF-beta.2002

    • Author(s)
      Takekawa, M., Takebayashi, K., Itoh, F., Adachi, M., Saito, H., Imai.K.
    • Journal Title

      EMBO J. 21

      Pages: 6473-6482

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Green tea : Cancer preventive beverage and/or drug.2002

    • Author(s)
      Fujiki, H., Suganuma, M., Imai, K., Nakachi.K.
    • Journal Title

      Cancer Lett. 188

      Pages: 9-13

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] New classification of pancreatic intraductal papillary-mucinous tumour by mucin expression : Its relationship with potentialfor malignancy.2002

    • Author(s)
      Nakamura, A., Horinouchi, M., Goto, M., Nagata, K., Sakoda, K., Takao, S., Imai, K., Kim, Y.S., Sato, E., Yonezawa.S.
    • Journal Title

      J.Pathol. 197

      Pages: 201-210

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Differential involvement of the hypermethylator phenotype in hereditary and sporadic colorectal cancers with high-frequency microsatellite instability.2002

    • Author(s)
      Yamamoto.H., Min, Y., Itoh, F., Imsumran, A., Horiuchi, S., Yoshida, M., Iku, S., Fukushima, H., Imai.K
    • Journal Title

      Genes Chromosomes Cancer 33

      Pages: 322-325

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Personality types, lifestyle, and sensitivity to mental stress in association with NK activity. Int. J.2001

    • Author(s)
      Imai, K., Nakachi, K.
    • Journal Title

      Hygiene Environ. 203

      Pages: 1-7

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Personality types, lifestyle, and sensitivity to mental stress in association with NK activity.2001

    • Author(s)
      Imai, K.
    • Journal Title

      Int.J.Hygiene Environ. 203

      Pages: 1-7

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Expression of matrix metalloproteinases and tissue inhibitors of metallo-proteinases in human pancreatic adenocarcinomas : Clinicopathologic and prognostic significance of matrilysin expresssion.2001

    • Author(s)
      Yamamoto, H., Itoh, F., Iku, S., Adachi, Y., Fukushima, H., Sasaki, S., Mukaiya, M., Hirata, K., Imai.K.
    • Journal Title

      J.Clin.Oncol. 19

      Pages: 1118-1127

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Genetic and clinical features of human pancreatic ductal adenocarcinomas with widespread microsatellite instability.2001

    • Author(s)
      Yamamoto, H., Itoh, F., Fukushima, H., Sasaki, S., Perucho, M., Imai.K.
    • Journal Title

      Cancer Res. 61

      Pages: 3139-3144

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence an 11-year follow-up study of a general population.2000

    • Author(s)
      Imai, K., Matsuyama, S., Miyake, S., Suga, K., Nakachi.K
    • Journal Title

      Lancet 356

      Pages: 1795-1799

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence an 11-year follow-up study of a general population.2000

    • Author(s)
      Imai, K.
    • Journal Title

      Lancet 356

      Pages: 1795-1799

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Frequent hyper-methylation of CpG islands and loss of expression of the 14.3-3 sigma gene in human hepatocellular carcinoma.2000

    • Author(s)
      Iwata, N., Yamamoto, H., Sasaki, S., Itoh, F., Suzuki, H., Kikuchi, T., Kaneto, H., Iku, S., Ozeki, I., Endo, T., Imai.K.
    • Journal Title

      Oncogene 19

      Pages: 5298-5302

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Comparing antibody and small molecule therapies for cancer

    • Author(s)
      Imai K
    • Journal Title

      Nature Rev Cancer (In press)

    • Data Source
      KAKENHI-PROJECT-11181101
  • [Journal Article] Epigenetic inactivation of interferon regulatory factor genes in gastric cancer.

    • Author(s)
      Yamashita M, Toyota M, Suzuki H, Nojima M, Yamamoto E, Kamimae S, Watanabe Y, Kai M, Akashi H, Maruyama R, Sasaki Y, Yamano H, Sugai T, Shinomura Y, Imai K, Tokino T, Itoh F
    • Journal Title

      Cancer Sci (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Journal Article] Bmf is a possible mediator in histone deacetylase inhibitors FK228 and CBHA-induced apoptosis

    • Author(s)
      Zhang YB, Adachi M, Kawamura R, Imai K.
    • Journal Title

      Cell Death and Differ. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15603004
  • [Journal Article] Sulindac Enhances the Proteasome Inhibitor Bortezomib-Mediated Oxidative Stress and Anticancer Activity

    • Author(s)
      Minami T, Adachi M, Kawamura R, Zhang YB, Shinomura, Y, Imai K.
    • Journal Title

      Clin. Cancer Res. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15603004
  • [Patent] 前立腺癌の骨転移判定方法2018

    • Inventor(s)
      今井祐記、雑賀隆史、菊川忠彦、沢田雄一郎
    • Industrial Property Rights Holder
      株式会社プラスパプレインズ、今井祐記
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-198404
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Patent] 生体用微小神経電極針及び生体用微小神経電極針体の製造方法2018

    • Inventor(s)
      古澤義人、松坂義哉、中島敏、虫明元、小林弘、中台康紀、高橋善和
    • Industrial Property Rights Holder
      古澤義人、松坂義哉、中島敏、虫明元、小林弘、中台康紀、高橋善和
    • Industrial Property Rights Type
      特許
    • Acquisition Date
      2018
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Patent] 膜型ムチン様タンパク質の認識とその医療応用2017

    • Inventor(s)
      辻祥太郎,影山泰平,鷲見公太,辻真紀子,今井浩三ほか
    • Industrial Property Rights Holder
      地方独立行政法人神奈川県立病院機構, 国立大学法人東京大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017-01-16
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26460692
  • [Patent] 膜型ムチン様タンパク質の認識とその医療応用2016

    • Inventor(s)
      辻祥太郎、今井浩三、ほか
    • Industrial Property Rights Holder
      辻祥太郎、今井浩三、ほか
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-025689
    • Filing Date
      2016-02-15
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Patent] 膜型ムチン様タンパク質の認識とその医療応用2016

    • Inventor(s)
      辻祥太郎、今井浩三、ほか
    • Industrial Property Rights Holder
      辻祥太郎、今井浩三、ほか
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-025689
    • Filing Date
      2016-02-15
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Patent] 結合体及びその使用2015

    • Inventor(s)
      辻祥太郎、今井浩三
    • Industrial Property Rights Holder
      辻祥太郎、今井浩三
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-03-05
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Patent] がん幹細胞分子マーカー2014

    • Inventor(s)
      谷口博昭、今井浩三、片岡一則、西山伸宏、宮田完二郎、前田芳周
    • Industrial Property Rights Holder
      谷口博昭、今井浩三、片岡一則、西山伸宏、宮田完二郎、前田芳周
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-07-09
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Patent] 新規PIポリアミド2012

    • Inventor(s)
      大日方大亮、高橋悟、福田昇、藤原恭子
    • Industrial Property Rights Holder
      日本大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-05-08
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Patent] 新規遺伝子ACMG1のメチル化を指標とする胃癌の診断方法2009

    • Inventor(s)
      豊田実、今井浩三、株式会社ジェネティックラボ
    • Industrial Property Rights Holder
      豊田実、株式会社ジェネティックラボ
    • Acquisition Date
      2009-12-18
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Patent] Method for detection of diseases using colonic mucosa2009

    • Inventor(s)
      豊田実, 今井浩三
    • Industrial Property Rights Holder
      札幌医科大学
    • Filing Date
      2009-08-28
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Patent] 癌の検出方法および検出用キット、ならびに癌治療剤2008

    • Inventor(s)
      今井浩三
    • Industrial Property Rights Holder
      札幌医科大学
    • Industrial Property Number
      2008-121671
    • Filing Date
      2008-05-07
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Patent] 癌の検出方法および検出用キット、ならびに癌治療剤.2008

    • Inventor(s)
      鈴木 拓, 豊田 実, 今井浩三, 他2名
    • Industrial Property Rights Holder
      札幌医科大学
    • Industrial Property Number
      2008-121671
    • Filing Date
      2008-05-07
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Patent] 癌治療剤及び癌の治療方法2008

    • Inventor(s)
      今井浩三、佐々木茂、清藤勉
    • Industrial Property Rights Holder
      北海道公立大学法人札幌医科大学、株式会社免疫生物研究所
    • Filing Date
      2008-05-29
    • Data Source
      KAKENHI-PROJECT-17016060
  • [Patent] 肝癌治療剤および肝癌の治療法2007

    • Inventor(s)
      今井浩三、佐々木茂、清藤勉
    • Industrial Property Rights Holder
      北海道公立大学法人札幌医科大学、株式会社免疫生物研究所
    • Industrial Property Number
      2007-142308
    • Filing Date
      2007-05-29
    • Data Source
      KAKENHI-PROJECT-17016060
  • [Patent] 胃粘膜洗浄液を利用した疾患関連マーカー検出法2006

    • Inventor(s)
      今井浩三
    • Industrial Property Rights Holder
      札幌医科大学
    • Industrial Property Number
      2006-134878
    • Acquisition Date
      2006-05-12
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Patent] 胃粘膜洗浄液を利用した疾患関連マーカー検出法2006

    • Inventor(s)
      今井浩三, 豊田実他
    • Industrial Property Rights Holder
      北海道聖マリアンナ医科大学
    • Industrial Property Number
      2006-134878
    • Filing Date
      2006-05-15
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Patent] ACMG1のメチル化を指標とする胃癌の診断方法2005

    • Inventor(s)
      今井 浩三
    • Industrial Property Rights Holder
      札幌医科大学
    • Industrial Property Number
      2005-220779
    • Filing Date
      2005-07-29
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Patent] NSAIDを利用した癌治療用組成物2004

    • Inventor(s)
      安達正晃, 今井浩三
    • Industrial Property Rights Holder
      科技庁
    • Filing Date
      2004-03-08
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590273
  • [Presentation] GPRC5Aは前立腺癌の細胞増殖および骨転移を制御する2019

    • Author(s)
      沢田雄一郎, 菊川忠彦, 飯尾浩之, 榊原伊織, 吉田周平, 池戸葵, 柳原裕太, 佐伯法学, Balázs Gyōrffy, 岸田健, 大久保陽一郎, 中村圭靖, 宮城洋平, 雑賀隆史, 今井祐記
    • Organizer
      第28回泌尿器科分子・細胞研究会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] GPRC5A facilitates cell proliferation and bone metastasis of prostate cancer2019

    • Author(s)
      Sawada Y, Kikugawa T, Iio H, Yanagihara Y, Saeki N, Sakakibara I, Gyōrffy B, Kishida T, Miyagi Y, Saika T, Imai Y
    • Organizer
      the 34th Annual The European Association of Urology Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 先天的腓骨神経欠損マウスの原因遺伝子の同定2019

    • Author(s)
      桝和子、加藤千賀、三谷優太、石井万由子、林康紀、村谷匡史、水野聖哉、杉山文博、高橋智、加藤秀樹、桝正幸
    • Organizer
      先端モデル動物支援プラットフォーム 成果発表会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] 前立腺がん骨転移制御分子の解析2019

    • Author(s)
      沢田雄一郎, 菊川忠彦, 飯尾浩之, 榊原伊織, 吉田周平, 池戸葵, 柳原裕太, 佐伯法学, Balázs Gyōrffy, 岸田健, 大久保陽一郎, 中村圭靖, 宮城洋平, 雑賀隆史, 今井祐記
    • Organizer
      第9回Orthopaedic Research Club
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] MDGAファミリー分子群の欠失が引き起こすE/Iバランス偏移に伴う認知・行動異常の解析2019

    • Author(s)
      Razib Hossain, 多田 篤史, 黒川 直弘, 長澤 研, 琢磨 和晃, 尾嶋 大喜, 高橋 弘雄, 岸本泰司, 山本 融
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] Increased level of maternal RORγt enhances effect of poly(I : C) to induce fetal loss2019

    • Author(s)
      當銘幸貴、永田怜、佐々木哲也、高橋智、武井陽介
    • Organizer
      4th Annual Anatomy Group Meeting
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] ローズマリーの加熱処理によって生成された新規化合物の構造解析と生理活性について2019

    • Author(s)
      酒見裕香、Bu-chin Yu, 濱島留梨子、森岡優子、山中大介、伯野史彦、高橋伸一郎、新藤一敏
    • Organizer
      2019年度農芸化学会大会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] 自然免疫制御に関わる新規RING型E3(RNF126)の同定と機能解析2018

    • Author(s)
      阿部貴則、及川大輔、寺脇正剛、後藤栄治、高橋宏隆、大竹史明、川原裕之、堀居拓郎、畑田出穂、佐伯泰、田中啓二、澤崎達也、徳永文稔
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] HEGI is a novel mucin-like membrane protein that is useful for the diagnosis of malignant mesothelioma.2018

    • Author(s)
      Hiroshima K, Miyagi Y, Tsuji S, Imai K.
    • Organizer
      USCAP 2018 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] エビ・カニアレルギーに関する日本人のゲノムワイド関連解析2018

    • Author(s)
      賈 慧娟、野川 駿、高橋 祥子、斉藤 憲司、加藤 久典
    • Organizer
      第72回日本栄養・食糧学会大会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] HEGI is a novel mucin-like membrane protein that is useful for the diagnosis of malignant mesothelioma.2018

    • Author(s)
      Hiroshima K, Miyagi Y, Tsuji S, Imai K.
    • Organizer
      USCAP 2018 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 髄液代謝異常症とトランスフェリン糖鎖異性体2018

    • Author(s)
      村上友太、高橋浩一、星 京香、伊藤浩美、不破尚志、菅野真由美、山口芳樹、宮嶋雅一、新井 一、美馬達夫、本多たかし、齋藤 清、橋本康弘
    • Organizer
      第37回日本糖質学会年会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 新しい髄液代謝マーカー : 髄液過剰による認知症及び髄液漏出症の診断2018

    • Author(s)
      村上友太、高橋浩一、星 京香、伊藤浩美、齋藤 清、山口芳樹、宮嶋雅一、新井 一、美馬達夫、橋本康弘
    • Organizer
      BIO tech 2018
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] Functional analysis of the novel WASP mutation resulting in X-linked congenital neutropenia2018

    • Author(s)
      Masayuki Kobayashi, Chanda Bidisha, Muneyoshi Futami., Mizuho Yamashita, Mitsuhiro Hirano, Kazuaki Yokoyama, Yoichi Imai, Eigo Yusa, Rui Yamaguchi, Seiya Imoto, Satoru Miyano, Arinobu Tojo
    • Organizer
      80th annual meeting of the JSH
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] 自然免疫制御に関わる新規RING型E3(RNF126)の同定と機能解析2018

    • Author(s)
      阿部貴則、及川大輔、寺脇正剛、後藤栄治、高橋宏隆、大竹史明、川原裕之、堀居拓郎、畑田出穂、佐伯泰、田中啓二、澤崎達也、徳永文稔
    • Organizer
      第41回日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] Design and Modular De Novo Synthesis of 6-Aza-artemisinins2018

    • Author(s)
      高橋紀人
    • Organizer
      JSPS日中韓フォーサイト事業「A3アジア化学プロープ研究拠点事業若手研究者ミーティング」
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] Molecular analysis of the mutant gene for the peroneal muscular atrophy mouse先天的腓骨神経欠損マウスの原因遺伝子の同定2018

    • Author(s)
      桝和子, 加藤千賀, 三谷優太, 林康紀, 村谷匡史, 水野聖哉, 高橋智, 加藤秀樹, 桝正幸
    • Organizer
      第41回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] 早期乳がん予後予測バイオマーカーTP53 signatureの簡易測定法の開発と分子生物学的意義2018

    • Author(s)
      山口 茂夫、高橋 信、石田 孝宜、角川 陽一郎、野水 整、大内 憲明、加藤 俊介、石岡 千加史
    • Organizer
      第26回日本乳癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 脳脊髄液減少症における髄液バイオマーカー2018

    • Author(s)
      村上友太、星 京香、伊藤浩美、齋藤 清、宮嶋雅一、新井 一、高橋浩一、美馬達夫、光藤 尚、荒木信夫、橋本康弘
    • Organizer
      第71回日本自律神経学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 髄液糖鎖マーカーとしての脳型トランスフェリン2018

    • Author(s)
      村上友太、星 京香、伊藤浩美、不破尚志、安部英理子、齋藤 清、宮嶋雅一、新井 一、光藤 尚、荒木信夫、高橋浩一、美馬達夫、橋本康弘
    • Organizer
      第12回東北糖鎖研究会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] HEG1 is a Novel Mucin-like Membrane Protein That is Useful for the Diagnosis of Malignant Mesothelioma.2018

    • Author(s)
      Hiroshima K, Miyagi Y, Tsuji S, Imai K.
    • Organizer
      USCAP 2018 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06297
  • [Presentation] 細胞内領域によるDectin-1の種特異的リガンドスペクトラム調節機構2018

    • Author(s)
      本園 千尋、高野 智嗣、今井 崇史、園田 康平、山崎 晶
    • Organizer
      第91回日本生化学学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] 統合失調症脳における慢性炎症関連分子のジェネティックニューロパソロジー2018

    • Author(s)
      和田明、國井泰人、日野瑞城、松本純弥、長岡敦子、丹羽真一、竹島明、高橋均、那波宏之、柿田明美、笠井清登、矢部博興
    • Organizer
      第13回日本統合失調症学会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 6-アザーアルテミシニン群の設計とモジュラ一式迅速合成プロセスの開発2018

    • Author(s)
      高橋紀人、Bonepally Karunakar Reddy、松岡直弥、岩月正人、石山亜紀、穂苅玲、乙黒一彦、大村智、大栗博毅
    • Organizer
      第60回天然有機化合物討論会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] 新しい脳脊髄液代謝マーカーによる脳脊髄液漏出症の診断2018

    • Author(s)
      村上友太、高橋浩一、星 京香、伊藤浩美、齋藤 清、山口芳樹、宮嶋雅一、新井 一、美馬達夫、橋本康弘
    • Organizer
      BIO Japan 2018
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 髄液産生マーカーとしてのトランスフェリン2018

    • Author(s)
      村上友太、高橋浩一、星 京香、伊藤浩美、宮嶋雅一、新井 一、美馬達夫、本多たかし、齋藤 清、橋本康弘
    • Organizer
      京都髄液フォーラム2018
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] コムギ無細胞系を用いて作製した脱ユビキチン化酵素(DUB)プロテインアレイによるポリユビキチン鎖基質特異性とDUB阻害剤の選択性評価2018

    • Author(s)
      高橋宏隆、山中聡士、桒田翔平、後藤栄治、今井賢一郎、富井健太郎、佐藤裕介、深井周也、徳永文稔、澤崎達也
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] 短期間で学習可能なマウス用オペラント学習装置の開発とその評価2017

    • Author(s)
      外川龍之介, 高橋優斗, 奥畑大悟, 虫明元, 中尾光之, 片山統裕
    • Organizer
      文部科学省新学術領域研究 学術研究支援基盤形成 先端モデル動物支援プラットフォーム若手支援技術講習会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] 精神症状と顕著な姿勢反射障害を呈した、過去5年の進行性核上性麻痺の一解剖例(P-1-D09)2017

    • Author(s)
      佐野輝典, 川添僚也, 塚本忠, 杉山淳比古, 佐藤典子, 高橋祐二, 村田美穂, 齊藤祐子
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] インターロイキン-17Aの一塩基多型と痛み関連表現型との関連解析2017

    • Author(s)
      大岡静衣, 西澤大輔, 長谷川準子, 高橋香央里, 中山京子, 江畑裕子, 福田謙一, 池田和隆
    • Organizer
      第39回日本生物学的精神医学会・第47回日本神経精神薬理学会 合同年会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] 美原記念病院ブレインバンクからの年次報告(2016年)2017

    • Author(s)
      田野光敏、田村未来、佐藤愛海、青柳真一、飯島仁美、谷津隆之、諏訪部 桂、木村浩晃、高橋陽子、相沢勝健、赤津裕康、村山繁雄、高尾昌樹、美原 盤、美原恵里、美原 樹
    • Organizer
      第58回日本神経病理学会学術研究会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 外側視床下部脳内自己刺激におけるオピオイド神経とドパミン神経系の役割2017

    • Author(s)
      井手聡一郎, 高橋雄大, 高松幸雄, Uh1 GR, 曽良一郎, 池田和隆
    • Organizer
      第37回鎮痛薬・オピオイドベブチドシンポジウム
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] 死後脳内において高頻度にコピー数多型(CNV)が観察された統合失調症3症例の臨床的特徴について2017

    • Author(s)
      長岡敦子、國井泰人、松本純弥、和田明、日野瑞城、丹羽真一、那波宏之、高橋 均、柿田明美、赤津裕康、橋詰良夫、山本左近、尾関祐二、矢部博興
    • Organizer
      第12回日本統合失調症学会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 美原記念病院ブレインバンクからの年次報告2017

    • Author(s)
      田野光俊, 田村未来, 佐藤愛美, 青柳真一, 飯島仁美, 谷津隆之, 諏訪部桂, 木村浩晃, 高橋陽子, 相澤勝健, 赤津祐康, 村山繁雄, 高尾昌樹, 美原盤, 美原恵理, 美原樹
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 受容体型チロシンキナーゼRORIによる生存シグナル維持の分子基盤2017

    • Author(s)
      高橋隆
    • Organizer
      第21回日本がん分子標的治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 盗汗で発症し、治療後再発に至った中枢神経浸潤を伴うBurkitt Lymphomaの78歳男性の1解剖例(P-1-H04)2017

    • Author(s)
      永迫友規, 藤野悟央, 内尾直裕, 平賢一郎, 那須涼, 寺尾安生, 清水潤, 辻省次, 國松聡, 高橋美和子, 百瀬敏光, 池村雅子, 村山繁雄, 齊藤祐子
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] Oroxin modulates behavioral fear expression through noradrenergic neurons in the locus cooruleus2017

    • Author(s)
      高橋 徹、征矢 晋吾、Thomas J Mchugh、前島 隆、阿部 学、崎村 建司、櫻井 武
    • Organizer
      第40回日本神経科学大会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] 死後脳内において高頻度にコピー数多型(CNV)が観察された統合失調症3症例の臨床的特徴について2017

    • Author(s)
      長岡敦子, 國井泰人, 松本純弥, 和田明, 日野瑞城, 丹羽真一, 那波宏之, 高橋均, 柿田明美, 赤津裕康, 橋詰良夫, 山本左近, 尾関祐二, 矢部博興
    • Organizer
      第12回日本統合失調症学会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 転写因子ATF5の欠損は行動異常を引き起こす2017

    • Author(s)
      梅村真理子, 小倉多恵, 金子泰之, 中野春男, 高橋 滋, 高雄啓三, 宮川 剛, 高橋勇二
    • Organizer
      第40回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] Association between objectively measured physical activity and methylation of PYCARD gene in the Japanese general population2017

    • Author(s)
      Yuichiro Nishida, Yasuki Higaki, Naoto Taguchi, Megumi Hara, Kazuyo Nakamura, Hinako Nanri, Takeshi Imaizumi, Tatsuhiko Sakamoto Mikako Horita, Koichi Shinchi, Chisato Shimanoe, Ken Higashimoto, Hidenobu Soejima, and Keitaro Tanaka
    • Organizer
      The 21st International Epidemiological Association (IEA) World Congress of Epidemiology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 美原記念病院ブレインバンクからの年次報告(2016年度)2017

    • Author(s)
      田野光敏, 田村未来, 佐藤愛海, 青柳真一, 飯島仁美, 谷津隆之, 諏訪部 桂, 木村浩晃, 高橋陽子, 相澤勝健, 赤津裕康, 村山繁雄, 高尾樹, 美原 盤, 美原恵里, 美原 樹
    • Organizer
      第58回日本神経病理学会総会学術研究会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] CRISPR/Cas9による遺伝子改変マウス作製の実際2017

    • Author(s)
      高橋 智、水野聖哉、杉山文博
    • Organizer
      第2回日本ゲノム編集学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06276
  • [Presentation] 成人T細胞白血病リンパ腫に合併した急性骨髄性白血病治療中のウィルス感染症の発症2017

    • Author(s)
      神保光児、今井陽一、小川弥穂、平野光人、越智清純、川俣豊隆、横山和明、安井寛、大野伸広、内丸薫、東條有伸
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] GIRK2コンデイショナルKOマウスの作成とそのうつ様行動の解析:うつ様行動としての無動におけるGIRK2チャネルの役割2016

    • Author(s)
      本多幾多郎、荒木喜美、本田宗吉、高橋大貴、副田二三夫、三隅将吾、山村研一、高濱和夫
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 極めて優れた特異度と感度をしめす新規中皮腫マーカー分子の同定2016

    • Author(s)
      辻 祥太郎, 今井 浩三
    • Organizer
      第36回日本分子腫瘍マーカー研究会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Data Source
      KAKENHI-PROJECT-26460692
  • [Presentation] 新規中皮腫マーカー分子の同定2016

    • Author(s)
      辻 祥太郎, 松浦 利絵子, 今井 浩三
    • Organizer
      第7回Japan Mesothelioma Interest Group研究会
    • Place of Presentation
      JPタワー名古屋ホール&カンファランス(愛知県名古屋市)
    • Data Source
      KAKENHI-PROJECT-26460692
  • [Presentation] A new approach to the tumor suppression by an anti-erbB-2 trifunctional antibody. Poster Session2016

    • Author(s)
      Kato Y, Hirata H, Tsujisaki M, Matsune T, Adachi Y, Hinoda Y, Sasaki S, Imai K.
    • Organizer
      10th Joint Conference of the American Association for Cancer Research(AACR)and the Japanese Cancer Association(JCA)
    • Place of Presentation
      Maui, Hawaii, U.S.A.
    • Year and Date
      2016-02-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Serum biomarker screening for BRCTF1-targeted therapy. Poster Session2016

    • Author(s)
      Gunji H, Taniguchi H, Imai K, Kutomi G, Shima H, Miyagi Y, Zembutsu H.
    • Organizer
      10th Joint Conference of the American Association for Cancer Research(AACR)and the Japanese Cancer Association(JCA)
    • Place of Presentation
      Maui, Hawaii, U.S.A.
    • Year and Date
      2016-02-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Serum biomarker screening for BRCTF1-targeted therapy. Poster Session2016

    • Author(s)
      Gunji H, Taniguchi H, Imai K, Kutomi G, Shima H, Miyagi Y, Zembutsu H.
    • Organizer
      10th Joint Conference of the American Association for Cancer Research(AACR)and the Japanese Cancer Association(JCA)
    • Place of Presentation
      Maui, Hawaii, U.S.A.
    • Year and Date
      2016-02-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Presentation] A new approach to the tumor suppression by an anti-erbB-2 trifunctional antibody. Poster Session2016

    • Author(s)
      Kato Y, Hirata H, Tsujisaki M, Matsune T, Adachi Y, Hinoda Y, Sasaki S, Imai K.
    • Organizer
      10th Joint Conference of the American Association for Cancer Research(AACR)and the Japanese Cancer Association(JCA)
    • Place of Presentation
      Maui, Hawaii, U.S.A.
    • Year and Date
      2016-02-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Presentation] 熊本大学CARDにおけるマウス生殖工学技術-精巣上体尾部の冷蔵保存-2015

    • Author(s)
      梅野智子、福本紀代子、春口幸恵、近藤朋子、竹下由美、中牟田裕子、宮川あい、岩本まり、高橋 郁、土山修治、竹尾 透、中潟直己
    • Organizer
      第62回日本実験動物学会総会
    • Place of Presentation
      京都テルサ(京都府京都市)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 熊本大学CARDにおけるマウス生殖工学技術-体外受精-2015

    • Author(s)
      中牟田裕子、福本紀代子、春口幸恵、近藤朋子、竹下由美、梅野智子、宮川あい、岩本まり、高橋 郁、土山修治、竹尾 透、中潟直己
    • Organizer
      第62回日本実験動物学会総会
    • Place of Presentation
      京都テルサ(京都府京都市)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 今後の余生を如何にして健康に暮らすか2015

    • Author(s)
      今井浩三
    • Organizer
      東京いそ会15周年特別講演
    • Place of Presentation
      東京IVYホール(東京都渋谷区)
    • Year and Date
      2015-12-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Presentation] がん治療認定医の到達点と今後2015

    • Author(s)
      今井浩三
    • Organizer
      朝日がん大賞受賞講演
    • Place of Presentation
      前橋市市民文化会館(群馬県前橋市)
    • Year and Date
      2015-09-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Presentation] がんの新規分子診断・治療を目指したトランスレーショナル研究の展開 (口頭)2015

    • Author(s)
      今井浩三
    • Organizer
      日本癌学会・長與賞受賞記念講演
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] がん治療認定医の到達点と今後2015

    • Author(s)
      今井浩三
    • Organizer
      朝日がん大賞受賞講演
    • Place of Presentation
      前橋市市民文化会館(群馬県前橋市)
    • Year and Date
      2015-09-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 熊本大学CARDにおけるマウス生殖工学技術-精子凍結保存-2015

    • Author(s)
      福本紀代子、春口幸恵、近藤朋子、竹下由美、中牟田裕子、梅野智子、宮川あい、岩本まり、高橋 郁、土山修治、竹尾 透、中潟直己
    • Organizer
      第62回日本実験動物学会総会
    • Place of Presentation
      京都テルサ(京都府京都市)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 熊本大学CARDにおけるマウス生殖工学技術-胚移植-2015

    • Author(s)
      竹下由美、福本紀代子、春口幸恵、近藤朋子、中牟田裕子、梅野智子、宮川あい、岩本まり、高橋 郁、土山修治、竹尾 透、中潟直己
    • Organizer
      第62回日本実験動物学会総会
    • Place of Presentation
      京都テルサ(京都府京都市)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] がんの新規分子診断・治療を目指したトランスレーショナル研究の展開 (口頭)2015

    • Author(s)
      今井浩三
    • Organizer
      日本癌学会・長與賞受賞記念講演
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Presentation] 熊本大学CARDマウスバンクの活用2015

    • Author(s)
      岩本まり、福本紀代子、春口幸恵、近藤朋子、竹下由美、中牟田裕子、梅野智子、高橋 郁、土山修治、竹尾 透、中潟直己
    • Organizer
      第62回日本実験動物学会総会
    • Place of Presentation
      京都テルサ(京都府京都市)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 熊本大学CARDにおけるマウス生殖工学技術-胚の凍結保存-2015

    • Author(s)
      近藤朋子、福本紀代子、春口幸恵、竹下由美、中牟田裕子、梅野智子、宮川 あい、岩本まり、高橋 郁、土山修治、竹尾 透、中潟直己
    • Organizer
      第62回日本実験動物学会総会
    • Place of Presentation
      京都テルサ(京都府京都市)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 今後の余生を如何にして健康に暮らすか2015

    • Author(s)
      今井浩三
    • Organizer
      東京いその会15周年特別講演
    • Place of Presentation
      東京IVYホール(東京都渋谷区)
    • Year and Date
      2015-12-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 熊本大学CARDマウスバンクにおける寄託システムの効率化2015

    • Author(s)
      高橋郁、岩本まり、福本紀代子、春口幸恵、近藤朋子、竹下由美、中牟田裕子、梅野智子、宮川あい、土山修治、竹尾 透、中潟直己
    • Organizer
      第62回日本実験動物学会総会
    • Place of Presentation
      京都テルサ(京都府京都市)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 熊本大学CARD主催によるマウス生殖工学技術研修会2015

    • Author(s)
      春口幸恵、福本紀代子、近藤朋子、竹下由美、中牟田裕子、梅野智子、宮川あい、岩本まり、高橋 郁、土山修治、竹尾 透、中潟直己
    • Organizer
      第62回日本実験動物学会総会
    • Place of Presentation
      京都テルサ(京都府京都市)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 抗HTLV-1gp46中和ADCC抗体によるin vivo HTLV-1感染制御2014

    • Author(s)
      藤猪英樹, 清水衡, 高橋良明, 田中礼子, 田中勇悦
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所1号館講堂(東京)
    • Year and Date
      2014-08-24
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] HTLV-1gp46、OX40およびCD25を標的としたモノクローナル抗体によるHTLV-1感染細胞の制御2014

    • Author(s)
      高橋良明, 清水衡, 呂城拓也, 田中礼子, 國廣真里枝, 藤猪英樹, 田中勇悦
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-11
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] HTLV-1 Tax抗原はT細胞表面にCD83を誘導する : Tax陽性細胞のlive cell sorting2014

    • Author(s)
      藤猪英樹, 高橋良明, 田中礼子, 福島卓也, 友寄毅昭, 水口真理子, 中村正孝, 田中勇悦
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-11
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] がん分子標的創薬を指向した低酸素誘導因子(HIF)阻害剤の探索・開発研究2014

    • Author(s)
      嶋田清香、吉村彩、安田順信、高橋伸明、西村慎一、服部明、掛谷秀昭
    • Organizer
      文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
    • Place of Presentation
      万国津梁館(沖縄県・名護市)
    • Year and Date
      2014-05-12
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] アルツハイマー患者における血漿中マイクロRNAの解析と診断への応用, Analysis of circulating miRNAs in plasma from patients with Alzheimer's disease toward application for the diagnosis2014

    • Author(s)
      二瀬由宇、岡田沙矢香、竹田育子、高橋哲也、松本昌泰、田原栄俊
    • Organizer
      第37回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-26
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] アルツハイマー患者における血漿中マイクロRNAの解析と診断への応用, Analysis of plasma miRNAs in patients with Alzheimer's disease as applied to the diagnosis2014

    • Author(s)
      二瀬由宇、岡田沙矢香、竹田育子、高橋哲也、松本昌泰、田原栄俊
    • Organizer
      第6回日本RNAi研究会
    • Place of Presentation
      グランドプリンスホテル広島(広島県・広島市)
    • Year and Date
      2014-08-28
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] HTLV-1 Tax抗原はT細胞表面にCD83を誘導する : Tax陽性細胞のlive cell sorting2014

    • Author(s)
      藤猪英樹, 高橋良明, 田中礼子, 福島卓也, 友寄毅昭, 水口真理子, 中村正孝, 田中勇悦
    • Organizer
      第51回日本ウイルス学会九州支部総会
    • Place of Presentation
      城山観光ホテル(鹿児島県・鹿児島市)
    • Year and Date
      2014-09-05
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Heat-ShockによるHTLV-1 Taxおよびgp46タンパクの発現増強と感染促進2014

    • Author(s)
      國廣真里枝, 藤猪英樹, 西連寺剛, 高橋良明, 田中礼子, 田中勇悦
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-11
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 成人T細胞白血病ウイルス(HTLV-I)の感染予防ワクチン : ヒト化感染中和抗体2014

    • Author(s)
      田中勇悦, 清水衡, 高橋良明, 藤猪英樹, 田中礼子
    • Organizer
      第51回日本ウイルス学会九州支部総会
    • Place of Presentation
      城山観光ホテル(鹿児島県・鹿児島市)
    • Year and Date
      2014-09-06
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] A combination of the anti-fibroblast growth factor receptor 1 monoclonal antibody and interferon-a/b supresses human hepatic cancer cells in vitro and in vivo2014

    • Author(s)
      Kato Y, Hiromi H, Tujisaki M, Matsune T, Sasaki S, Hinoda Y, Shinomura Y, Imai K
    • Organizer
      41 Congress of the International Society of Oncology and Biomarkers
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 神奈川県立がんセンターにおけるがん関連試料の収集と提供2014

    • Author(s)
      宮城洋平, 今井浩三
    • Organizer
      第73回日本癌学会学術総会シンポジウム
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-26
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] HTLV-1感染者の新鮮及び培養PBMCのTax抗原発現 : Tax抗原簡便フローサイトメトリー(Tax-FCM)を用いた解析2014

    • Author(s)
      田中勇悦, 高橋良明, 藤猪英樹, 宮城拓也, 田中礼子, 友寄毅昭, 福島卓也
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所1号館講堂(東京)
    • Year and Date
      2014-08-23
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得2013

    • Author(s)
      谷口博昭、山本博幸、越川直彦、清木元治、今井浩三
    • Organizer
      第22回日本がん転移学会学術集会
    • Place of Presentation
      ホテルブエナビスタ松本(長野県松本市)
    • Year and Date
      2013-07-11
    • Data Source
      KAKENHI-PROJECT-24650632
  • [Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得2013

    • Author(s)
      谷口博昭、山本博幸、越川直彦、清木元治、今井浩三
    • Organizer
      第22回日本がん転移学会学術集会
    • Place of Presentation
      ホテルブエナビスタ松本
    • Data Source
      KAKENHI-PROJECT-23240129
  • [Presentation] Dysregulation of noncoding RNA genes and its clinical application.2013

    • Author(s)
      Suzuki H, Yamamoto E, Shinomura Y and Imai K.
    • Organizer
      Ninth AACR-Japanese Cancer Association Joint Conference “Breakthroughs in Basic and Translational Cancer Research”
    • Place of Presentation
      the Hyatt Regency Maui, Maui, HI, USA.
    • Year and Date
      2013-02-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] マイクロRNA遺伝子のエピジェネティクス異常と臨床応用2013

    • Author(s)
      鈴木 拓、丸山玲緒、鈴木 亮、清水 崇、原田 拓、山野泰穂、野島正寛、高塚伸太朗、新沼 猛、甲斐正広、篠村恭久、今井浩三
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23240129
  • [Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得とその臨床応用2013

    • Author(s)
      谷口博昭、山本博幸、伊東文生、今井浩三
    • Organizer
      第33回日本分子腫瘍マーカー研究会
    • Place of Presentation
      横浜市
    • Year and Date
      2013-10-02
    • Data Source
      KAKENHI-PROJECT-23240129
  • [Presentation] マイクロRNA 遺伝子のエピジェネティクス異常と臨床応用2013

    • Author(s)
      鈴木拓,山本英一郎,丸山玲緒,鈴木 亮,清水崇,原田拓,山野泰穂,野島正寛,高塚伸太朗,新沼猛、甲斐正広,篠村恭久,今井浩三
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-23240129
  • [Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得とその臨床応用2013

    • Author(s)
      谷口博昭、山本博幸、伊東文生、今井浩三
    • Organizer
      第33回日本分子腫瘍マーカー研究会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2013-10-02
    • Data Source
      KAKENHI-PROJECT-24650632
  • [Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得2013

    • Author(s)
      谷口博昭、山本博幸、今井浩三
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2013-10-04
    • Data Source
      KAKENHI-PROJECT-24650632
  • [Presentation] ウィルス複製を有利にするHTLV-1 Rexの新たな機能の可能性と宿主細胞への影響2013

    • Author(s)
      中野和民、安東友美、山岸誠、横山弘一、唐澤伸明、橋爪大明、高橋隆太郎、高橋碧、石田尚臣、大杉剛生、田中勇悦、David W. Brighty、渡邉俊樹
    • Organizer
      第2回ATLシンポジウム、第6回HTLV-1研究会・シンポジウム
    • Place of Presentation
      東京大学医科学研究所
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得とその臨床応用2013

    • Author(s)
      谷口博昭、山本博幸、伊東文生、今井浩三
    • Organizer
      第33回日本分子腫瘍マーカー研究会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23240129
  • [Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得2013

    • Author(s)
      谷口博昭、山本博幸、越川直彦、清木元治、今井浩三
    • Organizer
      第22回日本がん転移学会学術集会
    • Place of Presentation
      松本市
    • Data Source
      KAKENHI-PROJECT-24650632
  • [Presentation] 膵内分泌細胞の発生分化における大Maf群転写因子の役割2013

    • Author(s)
      大石久史、工藤崇、高橋智
    • Organizer
      第118回日本解剖学会
    • Place of Presentation
      香川
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得2013

    • Author(s)
      谷口博昭、山本博幸、越川直彦、清木元治、今井浩三
    • Organizer
      第22回日本がん転移学会学術集会
    • Place of Presentation
      松本市
    • Year and Date
      2013-07-11
    • Data Source
      KAKENHI-PROJECT-23240129
  • [Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得2013

    • Author(s)
      谷口博昭、山本博幸、今井浩三
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23240129
  • [Presentation] ヒストンメチル化酵素分子の発現亢進による乳癌細胞の悪性形質獲得2012

    • Author(s)
      谷口博昭,山本博幸,今井浩三
    • Organizer
      72回日本癌学会学術総会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-23240129
  • [Presentation] ターゲッティングのための抗体医薬による新治療戦略.2012

    • Author(s)
      今井浩三、佐々木茂、安井寛、谷口博昭
    • Organizer
      第28回日本DDS学会総会・シンポジウム「ターゲッティング」
    • Place of Presentation
      札幌
    • Year and Date
      2012-07-03
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] ピロール・イミダゾール(PI)ポリアミドを用いた前立腺癌に関連する融合遺伝子発現抑制の検討.2012

    • Author(s)
      大日方大亮,藤原恭子,伊藤亜希子,村田保貴,高山賢一,浦野友彦,福田 昇,相馬正義,永瀬浩喜,井上 聡,高橋 悟
    • Organizer
      第100回日本泌尿器科学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2012-04-21
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] miRNA alterations in cancer development2010

    • Author(s)
      高橋隆
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2010-09-23
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Colorectal Cancer Epigenetics2009

    • Author(s)
      Toyota M., Imai K.
    • Organizer
      International Society for Oncology and Biomarkers 37^<Th> Meeting
    • Place of Presentation
      Amsterdam, Netherlands
    • Year and Date
      2009-09-29
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Presentation] The role of epigenetic changes in cancer immunothelapy.2009

    • Author(s)
      Toyota M, Imai K
    • Organizer
      US-Japan Workshop on Immunological Molecular Markers in Oncology
    • Place of Presentation
      Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Presentation] Preventing oxidative stress : A new role for XBP1 and its candidate as a molecular target for cancer2008

    • Author(s)
      Adachi M, Liu Y, Zhao S, Hareyama M, Koong A, Imai K and Shinomura Y
    • Organizer
      The 6^<th> International Symposium on cancer research and therapy
    • Place of Presentation
      Tokyo
    • Year and Date
      2008-11-22
    • Data Source
      KAKENHI-PROJECT-19590566
  • [Presentation]2008

    • Author(s)
      安達正晃、劉耀華、Koong Albert, 今井浩三、篠村泰久
    • Organizer
      第17回日本癌病態治療研究会
    • Place of Presentation
      京都
    • Year and Date
      2008-06-26
    • Data Source
      KAKENHI-PROJECT-19590566
  • [Presentation] Epigenetic gene silencing and microRNA in human colon cancer. Symposium2008

    • Author(s)
      Toyota M, Imai K
    • Organizer
      36th Congress of the International Society for Oncodevelopmental Biology and Medicine
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Presentation] The role of DNA methylation changes in signaling pathway.2008

    • Author(s)
      Toyota M, Imai K
    • Organizer
      AACR Special Conference on Cancer Research: Cancer Epigenetics
    • Place of Presentation
      Boston, USA
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Presentation] XBP1の新しい機能 : 酸化ストレス応答への関与2008

    • Author(s)
      安達正晃、劉耀華、趙世光、Koong Albert, Rando Thomas, Dan Ruo, 今井浩三、篠村泰久
    • Organizer
      日本分子生物学会年会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-19590566
  • [Presentation] Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer.2007

    • Author(s)
      Toyota M, Suzuki H, Maruyama R, Akino K, Watanabe Y, Sasaki Y, Imai K, Tokino T, Shinomura Y
    • Organizer
      98th Annual Meeting of American Association for Cancer Research.
    • Place of Presentation
      Los Angeles
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Presentation] Epigenetic silencing of genes involved in signaling pathway. Symposium2007

    • Author(s)
      Toyota M, Suzuki H, Shinomura Y, Tokino T, Imai K
    • Organizer
      The 7th Joint Conference of the American Association for Cancer Research and the Japanese Cancer Association
    • Place of Presentation
      Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Presentation] 内在性ホルモンを利用した新たな放射線感受性亢進療法の開発2007

    • Author(s)
      安達正晃、今井浩三、晴山雅人、篠村恭久
    • Organizer
      第16回日本癌病態治療研究会
    • Place of Presentation
      東京
    • Year and Date
      2007-06-28
    • Data Source
      KAKENHI-PROJECT-19590566
  • [Presentation] IL-2シグナルと小胞体ストレスシグナル2007

    • Author(s)
      安達正晃, 劉耀華、今井浩三、篠村泰久
    • Organizer
      日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-14
    • Data Source
      KAKENHI-PROJECT-19590566
  • [Presentation] Frequent epigenetic inactivation of DICKKOPF family genes in gastrointestinal tumors.2007

    • Author(s)
      Suzuki H, Toyota M, Maruyama R, Imai K, Shinomura Y
    • Organizer
      35th Congress of the International Society for Oncodevelopmental Biology and Medicine
    • Place of Presentation
      Plaque, Czech Republic
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Presentation] Epigenetic silencing of genes involved in signaling pathways in gastric cancer. Symposium2007

    • Author(s)
      Toyota M, Imai K
    • Organizer
      5th Congress of the International Society for Oncodevelopmental Biology and Medicine
    • Place of Presentation
      Plaque, Czech Republic
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Presentation] Epigenetic inactivation of TCF2 in human tumors2006

    • Author(s)
      Toyota M, Terasawa K, Sagae S, Ogi K, Suzuki H, Maruyama R, Shinomura Y, Saito T, Imai K, Tokino T
    • Organizer
      97th Annual Meeting of American Association for Cancer Research
    • Place of Presentation
      Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Presentation] DNA methylation changes in cancer: application to diagnosis and therapy. Symposium2006

    • Author(s)
      Toyota M, Suzuki H, Shinomura Y, Imai K
    • Organizer
      34th Congress of the International Society for Oncodevelopmental Biology and Medicine
    • Place of Presentation
      Pasadena, USA
    • Data Source
      KAKENHI-PROJECT-17109008
  • [Presentation] 前立腺癌特異的融合遺伝子TMPRSS2-ERG の生成を抑制するピロール・イミダゾール(PI)ポリアミドの開発

    • Author(s)
      大日方大亮,藤原恭子,高山賢一,浦野友彦,永瀬浩喜,相馬正義,井上 聡,高橋 悟
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 東大医科研における橋渡し研究とその発展

    • Author(s)
      今井浩三
    • Organizer
      第103回日本病理学会総会
    • Place of Presentation
      広島国際会議場
    • Year and Date
      2014-04-24 – 2014-04-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Presentation] ピロール・イミダゾール(PI)ポリアミドを用いた、前立腺癌新規遺伝子治療薬の開発

    • Author(s)
      大日方大亮,藤原恭子,伊藤亜希子,村田保貴,芦苅大作,山口健哉,高山賢一,浦野友彦,藤村哲也,福田 昇,永瀬浩喜, 相馬正義,井上 聡,高橋 悟
    • Organizer
      第14回ホルモンと癌研究会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] マウス精巣上体尾部冷蔵保存液の開発

    • Author(s)
      土山修治、福本紀代子、春口幸恵、近藤朋子、竹下由美、中牟田裕子、梅野智子、高橋郁、古波蔵恵里、竹尾透、Ming-Wen Li、Kristy Kinchen、Jadine Vallelunga、K.C. Kent Lloyd、清水範彦、中潟直己
    • Organizer
      日本実験動物科学技術2014
    • Place of Presentation
      札幌コンベンションセンター(北海道・札幌市)
    • Year and Date
      2014-05-15 – 2014-05-17
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] デュタステリド投与中のPSA管理に関する考察~5ARIはPCaの診断に影響を及ぼすのか~

    • Author(s)
      高橋 悟
    • Organizer
      第65回西日本泌尿器科学会総会
    • Place of Presentation
      佐賀
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Significant interaction between ADIPOQ gene and higher BMI on HbAlc levels in a Japanese general population

    • Author(s)
      Shimanoe C, Higaki Y, Nishida Y, Hara M, Nanri H, Nakamura K, Imaizumi T, Sakamoto T, Taguchi N, Horita M, Shinchi K, Tanaka K, J-MICC Study Group
    • Organizer
      第25回日本疫学会学術総会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2015-01-21 – 2015-01-23
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 肺発がんの発育進展に関与する発がん促進・抑制作用について

    • Author(s)
      今井田克己
    • Organizer
      平成26年度「個体レベルでのがん研究支援活動」ワークショップ
    • Place of Presentation
      琵琶湖ホテル(大津市・滋賀県)
    • Year and Date
      2015-02-05 – 2015-02-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 東京大学医科学研究所におけるTRの現状と展望. シンポジウム2「我が国におけるトランスレーショナルリサーチの現状とこれからの展望」

    • Author(s)
      今井浩三
    • Organizer
      第51回日本臨床分子医学会学術集会
    • Place of Presentation
      東京国際フォーラム(東京)
    • Year and Date
      2014-04-11 – 2014-04-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] MSM/Ms由来ES細胞を用いたc-MafトランスジェニックMSM/Msマウスラインの作出と解析

    • Author(s)
      昇地高雅, 舘山浩紀, 山村研一, 高橋智, 荒木喜美
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] State-of-the-art lecture「proPSA:新規腫瘍マーカーとしての臨床応用への期待(座長)

    • Author(s)
      高橋 悟
    • Organizer
      第21回日本がん検診・診断学会
    • Place of Presentation
      前橋
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Interaction between interleukin1-β gene polymorphism and cigarette smoking on HbA1c in a Japanese general population

    • Author(s)
      Nishida Y, Hara M, Nanri H, Nakamura K, Imaizumi T, Sakamoto T, Higaki Y, Taguchi N, Horita M, Shinchi K, Tanaka K
    • Organizer
      20th IEA World Congress of Epidemiology
    • Place of Presentation
      Anchorage, U.S.A.
    • Year and Date
      2014-08-17 – 2014-08-21
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Association between objectively measured physical activity and serum adiponectin in the middle-agedpopulation

    • Author(s)
      Nishida Y, Higaki Y, Taguchi N, Hara M, Nakamura K, Nanri H, Imaizumi T, Sakamoto T, Shimanoe C, Horita M, Shinchi K, Tanaka K
    • Organizer
      第25回日本疫学会学術総会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2015-01-21 – 2015-01-23
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 我が国におけるトランスレーショナルリサーチの現状とこれからの展望

    • Author(s)
      今井浩三
    • Organizer
      第51回日本臨床分子医学会学術集会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2014-04-11 – 2014-04-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Presentation] Perceived stress and coping strategies in relation to body mass index : cross-sectional study of 12,045 Japanese men and women

    • Author(s)
      Shimanoe C, Hara M, Nishida Y, Nanri H, Otsuka Y, Nakamura K, Higaki Y, Imaizumi T, Taguchi N, Sakamoto T, Horita M, Shinchi K, Tanaka K
    • Organizer
      20th IEA World Congress of Epidemiology
    • Place of Presentation
      Anchorage, U.S.A.
    • Year and Date
      2014-08-17 – 2014-08-21
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 東大医科研における橋渡し研究とその発展

    • Author(s)
      今井浩三
    • Organizer
      第103回日本病理学会総会 特別企画
    • Place of Presentation
      広島国際会議場フェニックスホール(広島県・広島市)
    • Year and Date
      2014-04-24 – 2014-04-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 環境発がんのリスク評価における病理学の貢献

    • Author(s)
      今井田克己
    • Organizer
      第60回日本病理学会秋期特別集会シンポジウム1
    • Place of Presentation
      国立劇場おきなわ(沖縄県・那覇市)
    • Year and Date
      2014-11-20 – 2014-11-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 遺伝子改変マウス凍結精子とC57BL/6J凍結未受精卵子間での体外受精

    • Author(s)
      梅野智子、福本紀代子、春口幸恵、近藤朋子、竹下由美、中牟田裕子、岩本まり、高橋郁、古波蔵恵里、土山修治、竹尾透、中潟直己
    • Organizer
      日本実験動物科学技術2014
    • Place of Presentation
      札幌コンベンションセンター(北海道・札幌市)
    • Year and Date
      2014-05-15 – 2014-05-17
    • Data Source
      KAKENHI-PROJECT-221S0001
  • 1.  YACHI Akira (50045324)
    # of Collaborated Projects: 21 results
    # of Collaborated Products: 0 results
  • 2.  HINODA Yuji (10165128)
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  • 19.  森 武貞 (60028496)
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  • 20.  松岡 雄治 (70078773)
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  • 30.  葛巻 暹 (80091445)
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  • 31.  八木田 秀雄 (30182306)
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  • 34.  葛西 正孝 (10142134)
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  • 38.  UEDA Ryuzo (20142169)
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  • 44.  TOYOKUNI Shinya (90252460)
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  • 46.  YAMADA Yasuhiro (70313872)
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