Kakizuka Akira 垣塚彰

… Alternative Names

Researcher Number	80204329
Other IDs
External Links
Affiliation (Current)	2019: 京都大学, 生命科学研究科, 教授
Affiliation (based on the past Project Information) *help	2011 – 2019: 京都大学, 生命科学研究科, 教授 2014 – 2015: 京都大学, 大学院生命科学研究科, 教授 2009: Kyoto University, 大学院・生命科学研究科, 教授 2005 – 2009: 京都大学, 生命科学研究科, 教授 2002 – 2005: 京都大学, 大学院・生命科学研究科, 教授 … More
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Pathological medical chemistry / Biological Sciences / Basic Section 49010:Pathological biochemistry-related Except Principal Investigator Biological Sciences / Ophthalmology / Pathological medical chemistry / Urology / Dermatology
Keywords	Principal Investigator VCP / ポリグルタミン / AAA ATPase / アポトーシス / 細胞死 / 神経細胞死 / APL / アミノ酸修飾 / RAR / MJD … More Except Principal Investigator p97 / ポリグルタミン / VCP / 神経変性変異 / 分子シャペロン / 神経変性疾患 / レチノイン酸 / 急性前骨髄球性白血病 / 眼難治疾患 / Hsp104 / PCR / polyglutamine / 凝集体 / 前立腺癌 / 遺伝子機能 / 遺伝子治療 / FISH / 造血器腫瘍 / アポトーシス / 神経保護 / buthionine sulfoximine / 染色体異常 / アミロイド / AAA ATPase / TSTA system / PSA / 転座関連遺伝子 / 酵母 / GFP / レチノイン酸レセプター / IRF-1,-2 / 筋萎縮性側索硬化症 / ドミナント-ネガティブ / ポリグルタミン病 / keratosis / 機能ドメイン / プロスタグランジン受容体 / 凝集体形成 / Cell Cycle / AAA superfamily蛋白質 / アデノウイルス / G蛋白質 / レチノイン酸受容体 / 標的遺伝子 / ER stress / トロンボキサン受容体アイソフォーム / ドミナントナガティブ / 腎癌 / 細胞機能 / スクリーニング / 分化誘導療法 / AAA+ スーパーファミリー蛋白質 / トランスジェニックマウス / 細胞増殖・分化 / 化学発癌 / 変異マウス / MJD / 運動ニューロン / P19 CELLS / NAIP / 癌 / aggregates / コンフォーメーション病 / 細胞分化 / ポリグルタミン酸 / 脊髄 / SPINALOORD / 情報伝達 / トランスジェニックマウス / 角化症 / 転写因子ネットワーク / 体内分布 / プロスタグランジン受容体遺伝子 / 眼疾患 / 基本転写因子 / 構造変換 / トリブレットリピートインスタビリティー / ドミナント・ネガティブ / 細胞接着 / K14 promotor / molecular chaperone / ケラチン / CFTR / マシャドジュセフ病 / keratinocyte differentiation / 転写調節 / signal transduction / ダイナミックミューテーション / 転写因子 / 細胞内レチノイン酸結合蛋白 / Lewy body / 造血系 / 制御因子 / adenovirus vector / 細胞周期 / Alzheimer's disease / International Scientific Research / ligand binding / ブファリン / 細胞増殖 / 酵母プリオン / 国際学術 / target genes / Signal Transduction / 脳内分布 / DRPLA / Buthionine sulfooximine / 腺ガン / receptor isoform / 遺伝子欠損マウス / アポプトーシス / アンドロゲン反応性 / LNCaP細胞 / 特異的転写調節因子 / transcriptional mediators / トランスジェニック・マウス / 癌遺伝子治療 / 癌治療 / keratin / Retinoic acid / K14プロモーター / 表皮分化 / 転写因子復合体 / BCL2遺伝子 / 神経細胞死 / amyloid / 活性化酸素 / MOTOR NEURON / 創薬 / receptor abnormality / Cell Adhesion / 三酸化ヒ素 / トロンボキサン受容体異常症 / トリプレットリピートインスタビリティー / ウイルス発癌 / ミスセンス変異 / 転写調節因子 / Drug Design / プロスタノイド受容体分子進化 / P19細胞 / renal cancer / 癌化学療法 / プロスタサイクリン受容体体内分布 / 海外派遣 / prostate cancer / 歯状核赤核淡蒼球ルイ体萎縮症 / Am-80 / transcriptional control / prostaglandin / アデノウィルスベクター / HBP-1a / 受容体 / mutant mice / cross-seeding / gene receptor / 出芽酵母 / transcriptional regulator / androgen responsiveness / development / PML / レチノイド / トロンボキサン / ポリプレン酸 / ユビキチン・プロテアゾーム / プロスタグランジン / 胚発生 / 炎症性角化症 / IBMPFD / 受容体遺伝子 / gene therapy / ノックアウト・マウス / 細胞社会学 / DNA非結合型因子 / 分子医学 / INDUCTION / ラット脳EP_3受容体 / 細胞内情報伝達 / Cancer / レチノイドアンタゴニスト / 薬品設計 / 遺伝子特異的転写因子 / GCL6遺伝子 / 転写因子ファミリー / neuronal system / Transgenic mouse / Retinoic acid Receptor / 受容体アイソフォーム / 受容体リガンド結合 / 3酸化砒素 / 情報交換 / 分化 / MLL遺伝子 / Gene Therapy / 胸腺 / トロンボキサン受容体 / thromboxane receptor / LNCaP cell / フォルディング / parkinson's disease / Information Exchange / ubiquitin / 皮膚特異的発現 / AAA+ Superfamily蛋白質 / 分子誘導療法 / トリプレットリピート病 / Dominant-negative / neurodegerative disease / hematopoietic system / apoptosis / reactive oxveren species / 血小板異常症 / 転写活性化機構 / 誘導 / 小脳変性疾患 / 遺伝子 / LNCAP細胞 / ドラッグデザイン / GEP / 眼細胞生物学 / 細胞機能制御 / TRANSCRIPTION FACTORS / AML1遺伝子 / 脊髄性筋萎縮症 / 神経系 / TSTAsystem / 転写仲介因子 / Prostate cancer / コンフォーメーション / シグナル伝達 / ハンチントン病 / 発生 / AAA superfamily protein / Cdc48 / AAAスーパーファミリー蛋白質 / ノックアウトマウス / arsenic trioxide / receptor distribution / レイノイン酸レセプター / AMYOTOROPHICLATERAL SCLEROSIS Less

Elucidation of novel functions of VCP, a major ATPase in the cellPrincipal InvestigatorOngoing
- Principal Investigator
  
  垣塚彰
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kyoto University
Analyses on novel functions of VCP, a major ATPase in the cellPrincipal InvestigatorOngoing
- Principal Investigator
  
  垣塚彰
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
プロテアゾーム阻害下におけるユビキチン化蛋白質の除去機構の解明Principal Investigator
- Principal Investigator
  
  垣塚彰
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Development of neuroprotective drugs
- Principal Investigator
  
  Ikeda Hanako
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto University
Development of neuroprotective treatment for incurable ocular diseases
- Principal Investigator
  
  YOSHIMURA Nagahisa
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto University
Analyses of the function and regulation of VCP, a major ATPase in the cellsPrincipal Investigator
- Principal Investigator
  
  KAKIZUKA Akira
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
Mechanisms for the regulation of growth and cell death in cancer cellsPrincipal Investigator
- Principal Investigator
  
  KAKIZUKA Akira
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
異常蛋白質が引き起こす空胞形成の分子解析
- Principal Investigator
  
  堀清次
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
VCPのATPase活性を阻害する物質の検索Principal Investigator
- Principal Investigator
  
  垣塚彰
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
ポリグルタミンの凝集体形成、細胞障害におけるストレス蛋白質の役割
- Principal Investigator
  
  木村洋子
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Functional analyses of VCP protein in neuronal cell deathPrincipal Investigator
- Principal Investigator
  
  KAKIZUKA Akira
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
ポリグルタミンの凝集体形成、細胞障害におけるストレス蛋白質の役割
- Principal Investigator
  
  KIMURA Yoko
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
異常蛋白質が引き起こす空胞形成の分子解析
- Principal Investigator
  
  堀清次
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Molecular analyses of cell death and vacuole formation that are induced by abnormal protein accumulationPrincipal Investigator
- Principal Investigator
  
  KAKIZUKA Akira
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KYOTO UNIVERSITY
Development of As203-besed new chemotherapy for advanced prostate cancer
- Principal Investigator
  
  KAKEHI Yoshiyuki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  KAGAWA UNIVERSITY(FACULTY OF MEDICINE)
The Role of stress proteins in the aggregation and cytotoxicity of polyglutamine
- Principal Investigator
  
  KIMURA Yoko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
単一遺伝子異常による神経細胞死
- Principal Investigator
  
  池田穣衛
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tokai University
がん細胞におけるアポトーシスの分子解析Principal Investigator
- Principal Investigator
  
  垣塚彰
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
  Osaka Bioscience Institute
Molecular analysis on nqurodegenerationPrincipal Investigator
- Principal Investigator
  
  KAKIZUKA Akira
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  OSAKA BIOSCIENCE INSTITUTE(OBI)
THE ANALYSIS OF PATHOGENESIS OF AMYOTROPHIC LATERAL SCLEROSIS BASED ON THE ESTABLISHMENT OF IN VITRO MOTOR NEURONAL CELL LINES
- Principal Investigator
  
  TANABE Yasuto
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka Bioscience Institute
アポトーシスの分子解析とその癌治療への応用Principal Investigator
- Principal Investigator
  
  垣塚彰
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka Bioscience Institute
A novel gene transfer method for prostate-specific and potent expression and its utilization in gene therapy
- Principal Investigator
  
  KAKEHI Yoshiyuki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  KYOTO UNIVERSITY
ホルモン依存性プログラム細胞死の癌治療への応用Principal Investigator
- Principal Investigator
  
  垣塚彰
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka Bioscience Institute
  Kyoto University
Target genes and biological role of transcription factors in animal
- Principal Investigator
  
  ISHII Shunsuke
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  RIKEN INSTITUTE
Identification and analysis of the genes responsible for inherited neurodegenerative disordersPrincipal Investigator
- Principal Investigator
  
  KAKIZUKA Akira
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka Bioscience Institute
遺伝性神経変性症の原因遺伝子の同定と解析Principal Investigator
- Principal Investigator
  
  垣塚彰
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
急性前骨髄球性白血病の発症及び寛解機構の解析Principal Investigator
- Principal Investigator
  
  垣塚彰
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
遺伝性神経変性疾患の分子機構の解析Principal Investigator
- Principal Investigator
  
  垣塚彰
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
がん細胞分化機構の分子生物学的解明と分化誘導療法の臨床応用に関する基礎的研究
- Principal Investigator
  
  大野竜三
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hamamatsu University School of Medicine
ホルモン依存性プログラム細胞死の分子機構解析とその応用Principal Investigator
- Principal Investigator
  
  垣塚彰
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
rho p21 in Neural Development and PlasticityPrincipal Investigator
- Principal Investigator
  
  KAKIZUKA Akira, 成宮周
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  KYOTO UNIVERSITY
An animal model for keratosis
- Principal Investigator
  
  TANAKA Toshihiro, 今村貞夫
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Dermatology
- Research Institution
  KYOTO UNIVERSITY
急性前骨髄球性白血病の発症及び寛解機構の解析Principal Investigator
- Principal Investigator
  
  垣塚彰
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
がん細胞分化機構の分子生物学的の解明と分化誘導療法の臨床応用に関する基礎的研究
- Principal Investigator
  
  大野竜三
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hamamatsu University School of Medicine
造血器腫瘍における転座関連遺伝子の機能とその臨床応用
- Principal Investigator
  
  鎌田七男
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hiroshima University
ホルモン依存性プログラム細胞死の開発と応用Principal Investigator
- Principal Investigator
  
  垣塚彰
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
Information Exchange on Cancer Research with North American
- Principal Investigator
  
  YAMAMOTO Tadashi
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  The University of Tokyo
造血器腫瘍における転座関連遺伝子の機能とその臨床応用
- Principal Investigator
  
  鎌田七男
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hiroshima University
細胞の機能分化に関わる遺伝子制御ネッドワーク-遺伝子の階層的制御システム-
- Principal Investigator
  
  岩渕雅樹
- Project Period (FY)
  1993 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
急性前骨髄球性白血病の発症及び寛解機構の解析Principal Investigator
- Principal Investigator
  
  垣塚彰
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
ホルモン依存性プログラム細胞死の開発と応用Principal Investigator
- Principal Investigator
  
  垣塚彰
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyoto University
Structures and functions of the Prostanoid Receptors
- Principal Investigator
  
  NARUMIYA Shuh
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KYOTO UNIVERSITY

[Book] Innovative Medicine: Basic research and develpoment2015
- Author(s)
  Kakizuka, A.
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-15H01181
[Book] Annual Review神経　タンパク質の品質管理と神経変性2014
- Author(s)
  木村洋子、垣塚　彰　編集：鈴木則宏、祖父江元、荒木信夫、宇川義一、川原信隆
- Total Pages
  290
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-23249016
[Book] ヒトの分子生物学(分子生物学第2版(編集:柳田光弘、西田栄介、野田亮))2009
- Author(s)
  垣塚彰
- Publisher
  東京科学同人
- Data Source
  KAKENHI-PROJECT-17014043
[Book] 脳神経科学イラストレイテッド改訂第2版(第7章-6 ポリグルタミン病)2006
- Author(s)
  垣塚彰他(編集:森寿, 真鍋俊也, 渡辺雅彦, 岡野栄之, 宮川剛)
- Total Pages
  372
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-16390092
[Book] ポリグルタミン病(脳神経科学イラストレイテッド改訂第2版(編集:森寿、真鍋俊也、渡辺雅彦、岡野栄之、宮川剛))2006
- Author(s)
  垣塚彰
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17014043
[Book] 脳神経科学イラストレイテッド改訂第2版(第7章-6 ポリグルタミン病)2006
- Author(s)
  垣塚彰他(編集:森寿, 真鍋俊也, 渡辺雅彦, 岡野栄之, 宮川剛)
- Total Pages
  372
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17028028
[Book] 脳神経科学イラストレイテッド改訂第2版(第7章-6ポリグルタミン病)2006
- Author(s)
  垣塚彰, 他(編集森寿, 真鍋俊也, 渡辺雅彦, 岡野栄之, 宮川剛)
- Total Pages
  372
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Book] 脳神経科学イラストレイテッド改訂第2版(第7章-6 ポリグルタミン病)2006
- Author(s)
  垣塚彰他(編集:森寿, 真鍋俊也, 渡辺雅彦, 岡野栄之, 宮川剛)
- Total Pages
  372
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17014043
[Book] ゲノムと疾患(第7章ゲノムの不安定性と神経系疾患)2004
- Author(s)
  垣塚彰, 他(編集村松正實)
- Total Pages
  214
- Publisher
  南山堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] KUS121, a VCP modulator, attenuates ischemic retinal cell death viasuppressing endoplasmic reticulum stress.2017
- Author(s)
  Hata, M., Yoshimura, N., et al.
- Journal Title
  
  Scientific reports
  
  Volume: - Pages: 44873-44873
- DOI
  10.1038/srep44873
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K20255, KAKENHI-PROJECT-16K11285, KAKENHI-PROJECT-16H05151, KAKENHI-PROJECT-16K20316, KAKENHI-PROJECT-24249082, KAKENHI-PUBLICLY-16H01359
[Journal Article] Neurprotective efficacies by KUS121, a VCP modulator, on animal models of retinal degeneration.2016
- Author(s)
  Hasegawa, T. Yoshimura, N., et al.
- Journal Title
  
  Scientific reports
  
  Volume: 6 Pages: 31184-31184
- DOI
  10.1038/srep31184
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04994, KAKENHI-PROJECT-16K11285, KAKENHI-PROJECT-16H05151, KAKENHI-PROJECT-24249082, KAKENHI-PUBLICLY-16H01359
[Journal Article] Neuroprotective effects of VCP modulators in mouse models of glaucoma.2016
- Author(s)
  Nakano, N., Yoshimura, N., et al.
- Journal Title
  
  Heliyon
  
  Volume: 2 Pages: 96-96
- DOI
  10.1016/j.heliyon.2016.e00096
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01181, KAKENHI-PROJECT-15K15633, KAKENHI-PROJECT-16K11285, KAKENHI-PROJECT-16H05151, KAKENHI-PROJECT-24249082, KAKENHI-PUBLICLY-16H01359
[Journal Article] BTeam: A novel BRET-based biosensor for the accurate quantification of ATP concentration within living cells.2016
- Author(s)
  Yoshida T, Kakizuka A, Imamura H.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Pages: 39618-39618
- DOI
  10.1038/srep39618
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01181, KAKENHI-PUBLICLY-15H01401, KAKENHI-PROJECT-26291027, KAKENHI-PROJECT-16K14709
[Journal Article] VCP/Cdc48 rescues the growth defect of a GPI10 mutant in yeast.2016
- Author(s)
  Ohnuma, Y., Takata, T., Kawawaki, J., Yasuda, K., Tanaka, K., Kimura Y., and Kakizuka, A.
- Journal Title
  
  FEBS Letters
  
  Volume: 589 Pages: 576-580
- DOI
  10.1016/j.febslet.2015.01.017
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000014, KAKENHI-PROJECT-24249082, KAKENHI-PROJECT-26440070
[Journal Article] Coordinated Regulation of TIP60 and Poly(ADP-Ribose) Polymerase 1 in Damaged-Chromatin Dynamics.2016
- Author(s)
  Ikura M
- Journal Title
  
  Mol. Cel. Biol.
  
  Volume: Epub ahead of print Pages: 1595-1607
- DOI
  10.1128/mcb.01085-15
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K12203, KAKENHI-PUBLICLY-15H01181, KAKENHI-PROJECT-23221006, KAKENHI-PROJECT-26550028, KAKENHI-PROJECT-26281020
[Journal Article] Glucose-stimulated single pancreatic islets sustain increased cytosolic ATP levels during initial Ca2+ influx and subsequent Ca2+ oscillations2014
- Author(s)
  Tanaka T, Nagashima K, Inagaki N, Kioka H, Takashima S, Fukuoka H, Noji H, Kakizuka A, Imamura H.
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Pages: 2205-16
- DOI
  10.1074/jbc.m113.499111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249016, KAKENHI-PROJECT-24657101, KAKENHI-PROJECT-25461346, KAKENHI-PLANNED-26111004, KAKENHI-PLANNED-23115002, KAKENHI-PROJECT-25251016
[Journal Article] Diversity in ATP concentrations in a single bacterial cell population revealed by quantitative single-cell imaging.2014
- Author(s)
  Hideyuki Yaginuma, Shinnosuke Kawai, Kazuhito V. Tabata, Keisuke Tomiyama, Akira Kakizuka, Tamiki Komatsuzaki, Hiroyuki Noji, and Hiromi Imamura
- Journal Title
  
  Science Report
  
  Volume: 4 Pages: 6522-6522
- DOI
  10.1038/srep06522
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23115002, KAKENHI-PLANNED-23115007, KAKENHI-PROJECT-24249082, KAKENHI-PROJECT-25251016, KAKENHI-PROJECT-25287105, KAKENHI-PROJECT-25650044, KAKENHI-PROJECT-26291027, KAKENHI-PROJECT-26252064
[Journal Article] Novel vcp modulators mitigate major pathologies of rd10, a mouse model of retinitis pigmentosa.2014
- Author(s)
  Ikeda, H. O., Sasaoka, N., Koike, M., Nakano, N., Muraoka, Y., Toda, Y., Fuchigami, T., Shudo, T., Iwata, A., Hori, S., Yoshimura, N. & Kakizuka, A.
- Journal Title
  
  Sci Rep
  
  Volume: 4 Pages: 5970-5970
- DOI
  10.1038/srep05970
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249082
[Journal Article] Long-term oral administration of hop flower extracts mitigates Alzheimer phenotypes in mice.2014
- Author(s)
  Sasaoka N, Sakamoto M, Kanemori S, Kan M, Tsukano C, Takemoto Y, Kakizuka A.
- Journal Title
  
  PLoS One
  
  Volume: 9
- DOI
  10.1371/journal.pone.0087185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249016
[Journal Article] In vivo fluorescent ATP imaging of Drosophila melanogaster and Caenorhabditis elegans by using a genetically encoded fluorescent ATP biosensor optimized for low temperature2013
- Author(s)
  Tsuyama, Taiichi; Kishikawa, Jun-ichi; Han, Yong-Woon; Harada, Yoshie; Tsubouchi, Asako; Noji, Hiroyuki; Kakizuka, Akira; Yokoyama, Ken; Uemura, Tadashi; Imamura, Hiromi.
- Journal Title
  
  Anal Chem.
  
  Volume: 85(16) Pages: 7889-7896
- DOI
  10.1021/ac4015325
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22115006, KAKENHI-PLANNED-23115002, KAKENHI-PROJECT-23249016, KAKENHI-PROJECT-24657101, KAKENHI-PROJECT-25251016, KAKENHI-PROJECT-25440008
[Journal Article] VCP Is an Integral Component of a Novel Feedback Mechanism that Controls Intracellular Localization of Catalase and H2O2 Levels.2013
- Author(s)
  Murakami K, Ichinohe Y, Koike M, Sasaoka N, Iemura S, Natsume T, Kakizuka A.
- Journal Title
  
  PLoS One
  
  Volume: 8
- DOI
  10.1371/journal.pone.0056012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249016
[Journal Article] Prostaglandin E receptor EP1 forms a complex with dopamine D1 receptor and directs D1-induced cAMP production to adenylyl cyclase 7 through mobilizing Gβγ subunits in human embryonic kidney 293T cells.2013
- Author(s)
  Ehrlich AT, Furuyashiki T, Kitaoka S, Kakizuka A, Narumiya S.
- Journal Title
  
  Molecular Pharmacology
  
  Volume: 84 Pages: 476-486
- DOI
  10.1124/mol.113.087288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249016, KAKENHI-PROJECT-24689015, KAKENHI-PUBLICLY-25116517, KAKENHI-PUBLICLY-25116715
[Journal Article] Different dynamic movements of wild-type and pathogenic VCPs and their cofactors to damaged mitochondria in a Parkin-mediated mitochondrial quality control system.2013
- Author(s)
  Yoko Kimura, Junpei Fukushi, Seiji Hori, Noriyuki Matsuda, Kei Okatsu, Yukie Kakiyama, Junko Kawawaki, Akira Kakizuka, Keiji Tanaka
- Journal Title
  
  Genes Cells.
  
  Volume: 18 Pages: 1131-1143
- DOI
  10.1111/gtc.12103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06061, KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-23249016, KAKENHI-PROJECT-23570184
[Journal Article] Mdm20 Stimulates PolyQ Aggregation via Inhibiting Autophagy Through Akt-Ser473 Phosphorylation.2013
- Author(s)
  Yasuda K, Ohyama K, Onga K, Kakizuka A, Mori N
- Journal Title
  
  PLoS One.
  
  Volume: 16;8(12):e82523 Pages: 1-15
- DOI
  10.1371/journal.pone.0082523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300121, KAKENHI-PROJECT-23249016, KAKENHI-PROJECT-24650200
[Journal Article] 神経変性と細胞死2013
- Author(s)
  垣塚　彰
- Journal Title
  
  医学のあゆみ
  
  Volume: 246 Pages: 449-454
- Data Source
  KAKENHI-PROJECT-23249016
[Journal Article] Real-Time Imaging of Rabbit Retina with Retinal Degeneration by using Spectral-Domain Optical Coherence Tomography.2012
- Author(s)
  Muraoka Y et al.
- Journal Title
  
  PLoS ONE
  
  Volume: 7
- DOI
  10.1371/journal.pone.0036135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249016, KAKENHI-PROJECT-23390401, KAKENHI-PROJECT-23592603, KAKENHI-PROJECT-24249082, KAKENHI-PROJECT-24791850
[Journal Article] Maintaining ATP levels via the suppression of PERK-mediated rRNA synthesis at ER stress.2010
- Author(s)
  Okamoto, A., Koike, M., Yasuda, K., Kakizuka A.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Pages: 42-47
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] Valosin-containing protein (VCP) in novel feedback machinery between abnormal protein accumulation and transcriptional suppression.2010
- Author(s)
  Koike M, Fukushi J, Ichinohe Y, Higashimae N, Fujishiro M, Sasaki C, Yamaguchi M, Uchihara T, Yagishita S, Ohizumi H, Hori S, Kakizuka A.
- Journal Title
  
  J Biol Chem. (In press)
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] Glucosamine induces autophagy via an mTOR-independent pathway.2010
- Author(s)
  Shintani, T., Yamazaki, F., Katoh, T., Umekawa, M., Matahira, Y., Hori, S., Kakizuka, A., Totani, K., Yamamoto, K., Ashida, H.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 391
  
  Pages: 1775-1779
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] Enhanced ATPase activities as a primary defect of mutant valosin-containing proteins (VCPs) that cause inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia (IBMPFD).2010
- Author(s)
  Manno, A., Noguchi, M., Fukushi, J., Motohashi, Y., Kakizuka, A.
- Journal Title
  
  Genes Cells (in press)
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] 神経変性疾患とVCP2009
- Author(s)
  垣塚彰
- Journal Title
  
  Clinical Neuroscience 27
  
  Pages: 964-965
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] p97/valosine- containing protein (VCP) is highly modulated by phosphorylation and acetylation.2009
- Author(s)
  Mori-Konya, C., Kato, N., Maeda, R., Yasuda, K., Higashimae, N., Noguchi, M., Koike, M., Kimura, Y., Ohizumi, H., Hori, S., Kakizuka, A.
- Journal Title
  
  Genes Cells 14
  
  Pages: 483-497
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] An inhibitor of a deubiquitingating enzyme regulates ubiquitin homeostasis.2009
- Author(s)
  Kimura Y, Yashiroda H, Kudo T, Koitabashi S, Murata S, Kakizuka A, Tanaka K.
- Journal Title
  
  Cell 137
  
  Pages: 549-559
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] 神経変性疾患における異常タンパク質の凝集と除去に関与するVCP2009
- Author(s)
  垣塚彰
- Journal Title
  
  生体の科学 60
  
  Pages: 579-581
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] ヒトの分子生物学2009
- Author(s)
  垣塚彰
- Journal Title
  
  分子生物学第2版(編集:柳田光弘、西田栄介、野田亮)
  
  Pages: 261-273
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] Listeria monocytogenes ActA-mediated escape from autophagic recognition.2009
- Author(s)
  Yoshikawa, Y., Ogawa, M., Hain T., Yoshida, M., Fukumatsu, M., Kim, M., Mimuro, H., Nakagawa, I., Yanagawa, T., Ishii, T., Kakizuka, A., Sztul, E., Chakraborty, T., Sasakawa, C.
- Journal Title
  
  Nat Cell Biol.
  
  Pages: 1233-1240
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] Roles of VCP in human neurodegenerative disorders.2008
- Author(s)
  Kakizuka A.
- Journal Title
  
  Biochem. Soc. Trans. 36
  
  Pages: 105-10
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] Roles of VCP in human neurodegenerative disorders.2008
- Author(s)
  Kakizuka A.
- Journal Title
  
  Biochem Soc Trans. 36
  
  Pages: 105-108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] Direct detection of the interaction between recombinant soluble extracellular regions in the heterodimeric metabotropic gamma- aminobutyric acid receptor.2008
- Author(s)
  Nomura, R., Suzuki, Y., Kakizuka, A., Jingami, H.
- Journal Title
  
  J Biol Chem. 283
  
  Pages: 4665-4673
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] Direct detection of the interaction between recombinantsoluble extracellular regions in the heterodimeric metabotropic gamma-aminobutyric acid receptor.2008
- Author(s)
  Nomura R, Suzuki Y, Kakizuka A, Jingami H.
- Journal Title
  
  J Biol Chem. 283
  
  Pages: 4665-4673
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] 神経変性疾患に関わる蛋白質の種々の修飾2007
- Author(s)
  垣塚彰
- Journal Title
  
  蛋白質・核酸・酵素 (印刷中)
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] Involvement of valosin-containing protein(VCP)/p97 in the formation and clearance of abnormal protein aggregates.2007
- Author(s)
  Kobayashi T, Manno A, Kakizuka A.
- Journal Title
  
  Genes Cells 12
  
  Pages: 889-901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] 神経変性疾患に関わる蛋白質の種々の修飾2007
- Author(s)
  垣塚彰
- Journal Title
  
  蛋白質・核酸・酵素 (印刷中)
- Data Source
  KAKENHI-PROJECT-17028028
[Journal Article] Involvement of valosin-containing protein (VCP)/p97 in the formation and clearance of abnormal protein aggregates.2007
- Author(s)
  Kobayashi, T., Manno, A., Kakizuka, A.
- Journal Title
  
  Genes Cells. 12
  
  Pages: 889-901
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] 神経変性疾患にかかわる蛋白質の種々の修飾2007
- Author(s)
  垣塚彰、小池雅昭
- Journal Title
  
  蛋白質・核酸・酵素 52
  
  Pages: 768-773
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] In vivo analysis of the role of aberrant histone deacetylase recruitment and RAR alpha blockade in the pathogenesis of acute promyelocytic leukemia.2006
- Author(s)
  Matsushita, H., Scaglioni, P.P., Bhaumik, M., Rego, E.M., Cai, L. F, Majid, S.M., Miyachi, H., Kakizuka, A., Miller, W.H. Jr., Pandolfi, P.P.
- Journal Title
  
  J Exp Med. 203
  
  Pages: 821-828
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] Dominant-negative effect of mutant valosin-containing protein in aggresome formation.2006
- Author(s)
  Kitami, M.I., Kitami, T., Nagahama, M., Tagaya, M., Hori, S., Kakizuka, A., Mizuno, Y., Hattori, N.
- Journal Title
  
  FEBS Lett. 580
  
  Pages: 474-478
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] 神経変性疾患と小胞体ストレス2006
- Author(s)
  野口昌克, 垣塚彰
- Journal Title
  
  医学のあゆみ vol.216
  
  Pages: 4033-4039
- Data Source
  KAKENHI-PROJECT-17028028
[Journal Article] 神経変性疾患と小胞体ストレス2006
- Author(s)
  野口昌克, 垣塚彰
- Journal Title
  
  医学のあゆみ vol.216
  
  Pages: 4033-4039
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] Dominant-negative effect of mutation valosin-containing protein in aggresome formation.2006
- Author(s)
  Kitami, MI., Kitami, T., Nagahama, M., Tagaya, M., Hori, S., Kakizuka, A., Mizuno, Y., Hattori, N.
- Journal Title
  
  FEBS Lett. 580
  
  Pages: 474-478
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] PGC 1ファミリーと糖・脂質代謝2006
- Author(s)
  大泉宏, 垣塚彰
- Journal Title
  
  内分泌・糖尿病科 23
  
  Pages: 40-47
- Data Source
  KAKENHI-PROJECT-17028028
[Journal Article] 神経変性疾患と小胞体ストレス2006
- Author(s)
  野口昌克, 垣塚彰
- Journal Title
  
  医学のあゆみ 216
  
  Pages: 4033-4039
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] 神経変性疾患と核2006
- Author(s)
  垣塚彰
- Journal Title
  
  蛋白質・核酸・酵素 51
  
  Pages: 2269-2273
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] 神経変性疾患と小胞体ストレス2006
- Author(s)
  野口昌克, 垣塚彰
- Journal Title
  
  医学のあゆみ vol.216
  
  Pages: 4033-4039
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] PGC 1ファミリーと糖・脂質代謝2006
- Author(s)
  大泉宏, 垣塚彰
- Journal Title
  
  内分泌・糖尿病科 23
  
  Pages: 40-47
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] 神経変性疾患と核2006
- Author(s)
  垣塚彰
- Journal Title
  
  蛋白質・核酸・酵素 51
  
  Pages: 2269-2273
- Data Source
  KAKENHI-PROJECT-17028028
[Journal Article] Polyglutamine-expanded ataxin-3 activates mitochondrial apoptotic pathway by upregulating Bax and downregulating Bcl-xL.2006
- Author(s)
  Chou, A.H., Yeh, T.H., Kuo, Y.L., Kao, Y.C., Jou, M.J., Hsu, C.Y., Tsai, S.R., Kakizuka, A., Wang, H.L.
- Journal Title
  
  Neurobiol Dis. 21
  
  Pages: 333-345
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] In vivo analysis of the role of aberrant histone deacetylase recruitment and RARα blockade in the pathogenesis of acute promyelocytic leukemia.2006
- Author(s)
  Matsushita, H., Scaglioni, P.P., Bhaumik, M., Rego, E.M/, Cai, L.F., Majid, S.M., Miyachi, H., Kakizuka, A., Miller, W.H.Jr., Pandolfi, P.P.
- Journal Title
  
  J.ExP.Med. 203
  
  Pages: 821-828
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] ポリグルタミン病2005
- Author(s)
  垣塚彰
- Journal Title
  
  脳神経外科速報 15
  
  Pages: 543-549
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] Retinoid signaling competence and RARbeta-mediated gene regulation in the developing mammalian telencephalon.2005
- Author(s)
  Liao, W.L., Wang, H.F., Tsai, H.C., Chambon, P., Wagner, M., Kakizuka, A., Liu, F.C.
- Journal Title
  
  Dev Dyn. 232
  
  Pages: 887-900
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] - alpha, beta -unsaturated ketone is a core moiety of natural ligands for covalent binding to peroxisome proliferator-activated receptor gamma.2005
- Author(s)
  Shiraki, T., Kamiya, N., Shiki, S., Kodama, T.S., Kakizuka, A., Jingami, H.
- Journal Title
  
  J. Biol. Chem. 279
  
  Pages: 51376-51385
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] ATPase activity of Valosin-containing protein (VCP) is regulated by oxidative modification of the evolutionally conserved 522nd cysteine residue in Walker A motif.2005
- Author(s)
  Noguchi, M., Takata, T. Kimura, Y., Manno, A., Murakami, K., Koike, M., Ohizumi, H., Hori, S., Kakizuka A.
- Journal Title
  
  J. Biol. Chem. 280
  
  Pages: 41332-41341
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] Retinoid signaling competence and RARbeta-mediated gene regulation in the developing mammalian telencephalon.2005
- Author(s)
  Liao, W.L., Wang, H.F., Tsai, H.C., Chambon, P., Wagner, M., Kakizuka, A., Liu, F.C.
- Journal Title
  
  Dev. Dyn. 232
  
  Pages: 887-900
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] ポリグルタミン病2005
- Author(s)
  垣塚彰
- Journal Title
  
  脳神経外科速報 vol.15
  
  Pages: 543-549
- Data Source
  KAKENHI-PROJECT-17028028
[Journal Article] α, β-unsaturated ketone is a core moiety of natural ligands for covalent binding to peroxisome proliferator-activated receptor γ.2005
- Author(s)
  Shiraki, T., Kamiya, N., Shiki, S., Kodama, T.S., Kakizuka, A., Jingami, H.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 51376-51385
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] Induction of murine leukemia and lymphoma by dominant negative retinoic acid receptor α.2005
- Author(s)
  Wang, Y.A., Sheng, K., Ishida, Y., Wang, Y., Kakizuka, A., Brooks, S.C.
- Journal Title
  
  Mol.Carcinog. 44
  
  Pages: 252-261
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] ポリグルタミン病2005
- Author(s)
  垣塚彰
- Journal Title
  
  脳神経外科速報 vol.15
  
  Pages: 543-549
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] ATPase activity of p97/Valosin-containing protein (VCP) is regulated by oxidative modification of the evolutionally conserved cysteine 522 residue in Walker A motif.2005
- Author(s)
  Noguchi, M., Takata, T., Kimura, Y., Manno, A., Murakami, K., Koike, M., Ohizumi, H., Hori, S., Kakizuka A.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 41332-41341
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] ポリグルタミン病2005
- Author(s)
  垣塚彰
- Journal Title
  
  脳神経外科速報 vol.15
  
  Pages: 543-549
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] Induction of murine leukemia and lymphoma by dominant negative retinoic acid receptor alpha.2005
- Author(s)
  Wang, Y.A., Shen, K., Ishida, Y., Wang, Y., Kakizuka, A., Brooks, S.C.
- Journal Title
  
  Mol Carcinog. 44
  
  Pages: 252-261
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] Polyglutamine-expanded ataxin-3 activates mitochondrial apoptotic pathway by upregulating Bax and downregulating Bcl-x(L).2005
- Author(s)
  Chou, A.H., Yeh, T.H., Kuo, Y.L., Kao, Y.C., Jou, M.J., Hsu, C, Y., Tsai, S.R., Kakizuka, A., Wang, H.L.
- Journal Title
  
  Neurobiol Dis. 21
  
  Pages: 333-345
- Data Source
  KAKENHI-PROJECT-17014043
[Journal Article] The role of preexisting aggregates in Hsp104-dependent polyglutamine aggregate formation and epifenetic change of yeast prion2004
- Author(s)
  Kimura, Y., Koitabshi, S., Kakizuka, A., Fujita, T.
- Journal Title
  
  Genes to Cells 9
  
  Pages: 685-696
- Data Source
  KAKENHI-PROJECT-16015338
[Journal Article] A mutant ataxin-3 putative-cleavage fragment in brain of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration.2004
- Author(s)
  Goti, D., Katzen S.M., Mez, J., Kurtis, N., Kiluk, J., Ben-Haiem, L., Jenkins, N.A, Copeland, N.G., Kakizuka, A., Sharp, A.H., Ross, C.A., Mouton, P.R., Colmer V.
- Journal Title
  
  J.Neuroscience 24
  
  Pages: 10266-10279
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] Molecular clearance of ataxin-3 is regulated by a mammalian E4.2004
- Author(s)
  Matsumoto, M., Yada, M., Hatakeyama, H., Ishimoto, H., Tanimura, T., Tsuji, S., Kakizuka, A., Kitagawa, M., Nakayama, K.I.
- Journal Title
  
  EMBO J. 23
  
  Pages: 659-669
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] 肥満のモデル動物-新たな抗肥満モデル,ERRL1マウス2004
- Author(s)
  亀井康富, 垣塚彰
- Journal Title
  
  現代医療 36
  
  Pages: 99-104
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] Effective treatment of advanced solid tumors by the combination of Arsenic Trioxide and L-Buthionine-Sulfoximine.2004
- Author(s)
  Maeda, H., Hori, S., Ohizumi, H., Segawa, T., Kakehi, Y., Ogawa, O., Kakizuka, A.
- Journal Title
  
  Cell Death Differ. 7
  
  Pages: 737-746
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] Alteration in the cellular response to retinoic acid of a human acute promyelocytic leukemia cell line, UF-1, carrying a patient-derived mutant PML-RARα chimeric gene.2004
- Author(s)
  Sato, A., Imaizumi, M., Hoshi, Y., Rikiishi, T., Fujii, K., Kizaki, M., Kagechika, H., Kakizuka, A., Hayashi, Y., Iinuma K.
- Journal Title
  
  Leukemia Res. 9
  
  Pages: 959-967
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] コンフォメーション病2004
- Author(s)
  垣塚彰
- Journal Title
  
  細胞工学 23
  
  Pages: 1394-1399
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] ポリグルタミン病における創薬標的2004
- Author(s)
  堀清次, 垣塚彰
- Journal Title
  
  蛋白質・核酸・酵素 49
  
  Pages: 1118-1121
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] フォールディング病としての神経変性疾患とオルガネラ病2004
- Author(s)
  垣塚彰, 森正敏
- Journal Title
  
  蛋白質・核酸・酵素 49
  
  Pages: 1077-1085
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] 神経変性疾患と細胞死2004
- Author(s)
  垣塚彰
- Journal Title
  
  実験医学 22
  
  Pages: 134-139
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] The role of pre-existing aggregates in Hsp 104-dependent polyglutamine aggregate formation and epigenetic change of yeast prions.2004
- Author(s)
  Kimura, Y., Koitabashi, S., Kakizuka, A., Fujita, T.
- Journal Title
  
  Genes Cells 8
  
  Pages: 685-696
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] Physical and functional interaction between dorfin and valosin-containing protein that are colocalized in ubiquitylated inclusions in neurodegenerative disorders.2004
- Author(s)
  Ishigaki, S., Hishikawa, N., Niwa, J., Iemura, S., Natsume, T., Hori, S., Kakizuka, A., Tanaka, K., Sobue, G.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 51376-51385
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] 小胞体ストレスと神経変性疾患2004
- Author(s)
  野口昌克, 垣塚彰
- Journal Title
  
  Clinical Neurosicence 月刊臨床神経科学 22
  
  Pages: 1046-1051
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390092
[Journal Article] Polyglutamine diseases and molecular chaperones.2003
- Author(s)
  Kimura, Kakizuka.
- Journal Title
  
  IUBMB Life. 55
  
  Pages: 337-345
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13210155
[Presentation] ATP制御による難治性疾患の予防・治療戦略2016
- Author(s)
  垣塚　彰
- Organizer
  第38回日本生物学的精神医学会・第59回日本神経化学会大会合同年会
- Place of Presentation
  福岡国際会議場（福岡市）
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01181
[Presentation] プロテアゾーム阻害下におけるユヒキチン化蛋白質の消失機構の解析2016
- Author(s)
  垣塚　彰
- Organizer
  平成 28 年度科学研究費補助金新学術領域研究「ユヒキチンネオバイオロジー」班会議
- Place of Presentation
  シャトレーゼ　ガトーキングダムサッポロ（札幌市）
- Data Source
  KAKENHI-PUBLICLY-15H01181
[Presentation] ATP制御による難治性疾患の予防・治療戦略2016
- Author(s)
  垣塚　彰
- Organizer
  第38回日本生物学的精神医学会・第59回日本神経化学会大会合同年会
- Place of Presentation
  福岡国際会議場（福岡市）
- Invited
- Data Source
  KAKENHI-PROJECT-16H05151
[Presentation] プロテアゾーム阻害下におけるユビキチン化蛋白質の除去機構の解析2015
- Author(s)
  垣塚彰
- Organizer
  新学術領域「ユビキチンネオバイオロジー」平成27年度領域班会議
- Place of Presentation
  南房総富浦ロイヤルホテル（千葉県・南房総市）
- Year and Date
  2015-12-18
- Data Source
  KAKENHI-PUBLICLY-15H01181
[Presentation] VCP modulatorのCCR2欠損マウスにおけるドルーゼン抑制の機序2015
- Author(s)
  飯田悠人、池田華子、吉川宗光、畑匡侑、長谷川智子、村岡勇貴、垣塚彰、吉村長久
- Organizer
  119回日本眼科学会総会
- Place of Presentation
  ロイトン札幌ほか(札幌市）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-15K15633
[Presentation] プロテアゾーム阻害下におけるユビキチン化蛋白質の除去機構の解明に向けて2015
- Author(s)
  垣塚彰
- Organizer
  新学術領域「ユビキチンネオバイオロジー」平成27年度若手ワークショップ・第一回領域会議
- Place of Presentation
  アピカルイン京都（京都府・京都市）
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PUBLICLY-15H01181
[Presentation] ATP制御による難治性疾患の病態とゲノムストレスの軽減の可能性2015
- Author(s)
  垣塚彰
- Organizer
  BMB2015
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2015-12-04
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01181
[Presentation] Neuroprotective effect of a valosin-containing-protein ATPase inhibitor on late-stage retinal degeneration in a mouse model.2014
- Author(s)
  Tomoko Hasegawa, Hanako O. Ikeda, Yuki Muraoka1,Akira Kakizuka,Nagahisa Yoshimura.
- Organizer
  World Ophthalmology Congress
- Place of Presentation
  Japan, Tokyo
- Year and Date
  2014-04-05
- Data Source
  KAKENHI-PROJECT-24249082
[Presentation] Optical coherence tomography, electroretinography, and histological analysis of mouse models for retinal degeneration2013
- Author(s)
  Tomoko HasegawaHanako Ohashi Ikeda,1 Noriko Nakano,1 Yuki Muraoka,1 Akira Kakizuka,4 Nagahisa Yoshimura1
- Organizer
  ARVO 2013
- Place of Presentation
  Seattle
- Data Source
  KAKENHI-PROJECT-24249082
[Presentation] Novel VCP inhibitors mitigate major pathologies in mouse models of glaucoma and retinitis pigmentosa by their neuroprotective effects.2013
- Author(s)
  Akira Kakizuka
- Organizer
  EMBO workshop “AAA+ proteins: from mechanism and disease targets”
- Place of Presentation
  Neuss (Germanry)
- Invited
- Data Source
  KAKENHI-PROJECT-23249016
[Presentation] VCP 阻害剤によるＣＣＲ２欠損マウスのドルーゼン抑制効果の検討2013
- Author(s)
  村岡勇貴、池田華子、中野紀子、長谷川智子、垣塚彰、吉村長久
- Organizer
  日本眼科学会１１7回
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24249082
[Presentation] 新規創薬標的としての細胞内主要ATPase、VCP2013
- Author(s)
  垣塚　彰
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-23249016
[Presentation] VCP阻害剤による網膜神経保護効果のメカニズム2013
- Author(s)
  池田華子、中野紀子、村岡勇貴、長谷川智子、垣塚彰、吉村長久
- Organizer
  日本眼科学会１１7回
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24249082
[Presentation] VCP阻害剤によるグラスト欠損マウスにおける神経保護効果の検討2013
- Author(s)
  中野紀子、池田華子、村岡勇貴、板谷正紀、垣塚彰、吉村長久
- Organizer
  日本眼科学会１１7回
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24249082
[Presentation] 新規神経保護創薬標的としての細胞内主要ATPase、VCP2013
- Author(s)
  垣塚　彰
- Organizer
  「病態に根ざしたALSの新規治療法開発」分科班平成25年度ワークショップ
- Place of Presentation
  都市センターホテル
- Invited
- Data Source
  KAKENHI-PROJECT-23249016
[Presentation] A Novel Valosin-Containing Protein Inhibitor Suppresses Photoreceptor Degeneration in a Rabbit Model of Retinitis Pigmentosa2013
- Author(s)
  Yuki Muraoka,1 Hanako Ohashi Ikeda,1 Noriko Nakano,1 Tomoko Hasegawa,1 Kondo Mineo,2 Hiroko Terasaki,3 Akira Kakizuka,4 Nagahisa Yoshimura1
- Organizer
  ARVO 2013
- Place of Presentation
  Seattle
- Data Source
  KAKENHI-PROJECT-24249082
[Presentation] Neuroprotective effect of valosin-containing protein inhibitors on mice models of glaucoma2013
- Author(s)
  Hanako Ohashi Ikeda、Noriko Nakano,Yuki Muraoka, Masanori Hangai, Akira Kakizuka, Nagahisa Yoshimura
- Organizer
  ARVO 2013
- Place of Presentation
  Seattle
- Data Source
  KAKENHI-PROJECT-24249082
[Presentation] 新規創薬標的としての細胞内主要ATPase、VCP2013
- Author(s)
  垣塚　彰
- Organizer
  第22回日本Cell Death学会学術集会
- Place of Presentation
  京都大学
- Invited
- Data Source
  KAKENHI-PROJECT-23249016
[Presentation] Trials for the prevention of incurable disease models by the regulation of ATP2013
- Author(s)
  垣塚　彰
- Organizer
  京都大学生命科学研究科シンポジウム
- Place of Presentation
  京都大学
- Invited
- Data Source
  KAKENHI-PROJECT-23249016
[Presentation] 新規創薬標的としての細胞内主要ATPase、VCP2013
- Author(s)
  垣塚　彰
- Organizer
  上原記念生命科学財団特定研究助成　革新的医療を創生する医学研究
- Place of Presentation
  下田セントラルホテル
- Invited
- Data Source
  KAKENHI-PROJECT-23249016
[Presentation] VCP as a novel drug target for currently non-curable eye disorders2013
- Author(s)
  Akira Kakizuka
- Organizer
  BioJapan 2013
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-23249016
[Presentation] 新規神経保護薬の開発とその緑内障動物モデルに対する応用2012
- Author(s)
  垣塚　彰
- Organizer
  第２３回日本緑内障学会
- Place of Presentation
  石川県立音楽堂
- Invited
- Data Source
  KAKENHI-PROJECT-23249016
[Presentation] Roles of VCP in neurodegenerative disorders2012
- Author(s)
  Akira Kakizuka
- Organizer
  The 10th NTU-Japan International mini-symposium on Molecular and Cell biology & Promotion of Academic Exchange and Collaborations for NTU-Japan
- Place of Presentation
  Taiwan National University (Taiwan)(招待講演)
- Year and Date
  2012-01-08
- Data Source
  KAKENHI-PROJECT-23249016
[Presentation] 神経変性疾患およびストレス応答におけるVCPの役割2011
- Author(s)
  垣塚彰
- Organizer
  第20回日本Cell Death学会
- Place of Presentation
  東京大学薬学講堂(東京)(招待講演)
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PROJECT-23249016
[Presentation] VCPが関わる異常蛋白質に対するストレス応答機構とATP制御機構2011
- Author(s)
  垣塚彰
- Organizer
  第84回日本生化学会大会シンポジウム(2S2a)ストレスシグナル研究の最前線
- Place of Presentation
  京都国際会議場(京都)(招待講演)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23249016
[Presentation] Roles of VCP in polyglutamine diseases2011
- Author(s)
  Akira Kakizuka
- Organizer
  Asian Aging Core for Longevity-Nagasaki Symposium Asian Aging 2011
- Place of Presentation
  Nagasaki University (Japan)(招待講演)
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-23249016
[Presentation] Roles of VCP in abnormal phospholipid metabolisms in polyglutamine disease models2011
- Author(s)
  Akira Kakizuka
- Organizer
  9th International conference on AAA proteins
- Place of Presentation
  Kumamoto City International Center (Japan)(招待講演)
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-23249016
[Presentation] 細胞内ATPの制御機構2011
- Author(s)
  垣塚彰
- Organizer
  第13回京都大学生命科学研究科シンポジウム
- Place of Presentation
  芝蘭会館(京都)(招待講演)
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-23249016
[Presentation] Roles of VCP in human neurodegenerative disorders2011
- Author(s)
  Akira Kakizuka
- Organizer
  Kyoto University day in Nanjing
- Place of Presentation
  Nanjing University (China)(招待講演)
- Year and Date
  2011-12-02
- Data Source
  KAKENHI-PROJECT-23249016
[Presentation] ストレス応答におけるVCP蛋白質の役割2009
- Author(s)
  垣塚彰
- Organizer
  第82回日本生化学会シンポジウム「ストレス応答の新機軸」
- Place of Presentation
  神戸国際会議場
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] A novel feedback machinery between abnormal protein accumulation and transcriptional suppression.2009
- Author(s)
  Akira Kakizuka
- Organizer
  The 5th NTU-Kyoto-U mini-symposium on molecular and cellular biology.
- Place of Presentation
  Raku-yu Kaikan, Kyoto, Japan.
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] 細胞周期におけるVCP/p97のリン酸化の役割の解析: Roles of VCP phosphorylation in cell cycle progression2009
- Author(s)
  加藤成芳、村上克洋、紺谷千穂、堀清次、垣塚彰
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] 細胞機能におけるVCP蛋白質の役割2009
- Author(s)
  垣塚彰
- Organizer
  第10回京都大学生命科学研究科シンポジウム
- Place of Presentation
  芝蘭会館
- Year and Date
  2009-07-02
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] 癌ってどうゆうもの?2009
- Author(s)
  垣塚彰
- Organizer
  膳所高等学校・京都大学公開講義
- Place of Presentation
  京都大学
- Year and Date
  2009-05-08
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] 酵母のGP110温度感受性変異株で見られる出芽阻害とDNA過剰複製: Budding defect and DNA over-replication in a yeast GP110 temperature-sensitive mutant2009
- Author(s)
  大沼洋平、高田尚寛、安田邦彦、垣塚彰
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] p97/VCPのATPase活性に作用する新規翻訳後修飾の同定: Identification of novel post-translational modifications which affect the ATPase activity of p97/VCP2009
- Author(s)
  紺谷千穂、加藤成芳、前田良太、小池雅昭、安田邦彦、野口昌克、東前直樹、木村洋子、大泉宏、堀清次、垣塚彰
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] ストレス応答におけるVCP蛋白質の役割, ストレス応答の新機軸2009
- Author(s)
  垣塚彰
- Organizer
  第82回日本生化学会シンポジウム
- Place of Presentation
  神戸国際会議場
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] 分子が織りなす生命の不思議-どうして病気になるの? 運動しても肥満は防げない? がん・神経難病、肥満・糖尿病をめぐって-2008
- Author(s)
  垣塚彰
- Organizer
  徳島県立総合大学校まなーびあ徳島開校記念講演
- Place of Presentation
  徳島県立総合教育センター(徳島県板野郡)
- Year and Date
  2008-06-08
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] VCPはペルオキシソームマトリックスタンパク質の輸送と分解に関与する : VCP is involved in peroxisomal matrix protein import and degradation2008
- Author(s)
  村上克洋、垣塚彰
- Organizer
  BMB2008
- Place of Presentation
  神戸国際会議場
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] ヒト子宮頸癌及び食道癌におけるVCP co-factor p47の発現上昇による浸潤能の獲得 : Overexpression of p47, a VCP co-factor, in potential acquisition of invasion activities in human esophageal and cervical cancer2008
- Author(s)
  一戸勇弦、東前直樹、大泉宏、垣塚彰
- Organizer
  BMB2008
- Place of Presentation
  神戸国際会議場
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] 小胞体ストレスに対する新規応答機構 : Inhibition of rRNA synthesis in response to ER stress2008
- Author(s)
  岡本暁彦、安田邦彦、垣塚彰
- Organizer
  BMB2008
- Place of Presentation
  神戸国際会議場
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] 異常蛋白質の蓄積がもたらすフィードバック機構2008
- Author(s)
  垣塚彰
- Organizer
  第9回京都大学生命科学研究科シンポジウム
- Place of Presentation
  京大会館
- Year and Date
  2008-06-26
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] 分子が織りなす生命の不思議-どうして病気になるの? 運動しても肥満は防げない? がん・神経難病、肥満・糖尿病をめぐって-2008
- Author(s)
  垣塚彰
- Organizer
  徳島県立総合大学校まな-びあ徳島開校記念講演
- Place of Presentation
  徳島県立総合教育センター
- Year and Date
  2008-06-08
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] 癌ってどうゆうもの2007
- Author(s)
  垣塚彰
- Organizer
  膳所高等学校・京都大学公開講義
- Place of Presentation
  京都大学
- Year and Date
  2007-04-27
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] Roles of VCP in human neurodegenerative disorders2007
- Author(s)
  Kakizuka A.
- Organizer
  7th international conference on AAA proteins
- Place of Presentation
  Royal Agricultural College, Cirencester(England)
- Year and Date
  2007-09-11
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] Roles of VCP in human neurodegenerative disorders2007
- Author(s)
  Akira Kakizuka
- Organizer
  7th international conference on AAA proteins.
- Place of Presentation
  Royal Agricultural College, Cirencester (England)
- Year and Date
  2007-09-11
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] VCP蛋白質の機能解析, 細胞死研究の新たな展開と関連する素過程2006
- Author(s)
  垣塚彰
- Organizer
  平成18年度生理学研究所研究会
- Place of Presentation
  生理学研究所
- Year and Date
  2006-10-31
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] 「癌ってどういうもの?」文部科学省科学研究費補助金特定領域研究「がん特定」公開シンポジウム「高校生の諸君に伝えたい、がん研究の今!」2006
- Author(s)
  垣塚彰
- Organizer
  第3回出前授業
- Place of Presentation
  徳島県立城南高等学校
- Year and Date
  2006-11-20
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] ATPase activity of Valosin-containing protein (VCP) is regulated by oxidative modification of the evolutionally conserved 522nd cysteine residue in Walker A motif2005
- Author(s)
  Akira Kakizuka
- Organizer
  6th international conference on AAA proteins.
- Place of Presentation
  Schloss Seggau, Austria
- Year and Date
  2005-09-15
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] 細胞周期におけるVCP蛋白質の機能解析2005
- Author(s)
  垣塚彰
- Organizer
  第78回日本生化学会大会ランチョンセミナー
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2005-10-20
- Data Source
  KAKENHI-PROJECT-17014043
[Presentation] Neuroprotective effects of a VCP modulator on rat models of ischemia and reperfusion-induced retinal degeneration
- Author(s)
  Masayuki Hata, Hanako O. Ikeda, Tomoko Hasegawa, Noriko Nakano, Yuki Muraoka, Akira Kakizuka, Nagahisa Yoshimura
- Organizer
  ARVO2014
- Place of Presentation
  Orland, Fla., USA
- Year and Date
  2014-05-04 – 2014-05-08
- Data Source
  KAKENHI-PROJECT-24249082
[Presentation] 網膜虚血再灌流ラットモデルにおけるvalosin-containing protein modifierの神経保護効果の検討
- Author(s)
  畑匡侑、池田華子、飯田悠人、吉川宗光、長谷川智子、村岡勇貴、垣塚彰、吉村長久
- Organizer
  ５３回日本網膜硝子体学会総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-11-28 – 2014-11-30
- Data Source
  KAKENHI-PROJECT-24249082

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Kakizuka Akira 垣塚 彰

KAKIZUKA Akira 垣塚 彰

Research Projects

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Co-Researchers

Elucidation of novel functions of VCP, a major ATPase in the cellPrincipal InvestigatorOngoing

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Analyses on novel functions of VCP, a major ATPase in the cellPrincipal InvestigatorOngoing

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プロテアゾーム阻害下におけるユビキチン化蛋白質の除去機構の解明Principal Investigator

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Analyses of the function and regulation of VCP, a major ATPase in the cellsPrincipal Investigator

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Mechanisms for the regulation of growth and cell death in cancer cellsPrincipal Investigator

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VCPのATPase活性を阻害する物質の検索Principal Investigator

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Functional analyses of VCP protein in neuronal cell deathPrincipal Investigator

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Molecular analyses of cell death and vacuole formation that are induced by abnormal protein accumulationPrincipal Investigator

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Kakizuka Akira 垣塚彰

KAKIZUKA Akira 垣塚彰