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YOSHIDA Mituaki  吉田 光昭

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… Alternative Names

YOSHIDA Mitsuaki  吉田 光昭

吉田 光昭和

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Researcher Number 80012607
Affiliation (Current) 2022: 公益財団法人がん研究会, がん化学療法センター, 所長
Affiliation (based on the past Project Information) *help 2009: 東京大学, 大学院・新領域創成科学研究科, 教授
2000: Professor, The Institute for Medical Science, The Tokyo University, 医科学研究所, 教授
1999: 萬有製薬株式会社, つくば研究所, 所長
1989 – 1998: 東京大学, 医科学研究所, 教授
1996 – 1997: Institute of Medical Science, University of Tokyo, 医科学研究所, 所長 … More
1994 – 1995: 東京大学医科学研究所, 細胞化学研究部, 教授
1994: 東大, 医科研, 教授
1991: 東京大学医科学研究所, 教授
1989: (財)癌研究会, 癌研究所・ウイルス腫瘍部, 部長
1988: (財)癌研究会研究所, 部長
1987: (財)癌研究会, 癌研究所・ウイルス腫瘍部, 部長
1987: (財)癌研究会癌研究所, 部長
1986 – 1987: 癌研究会癌研究所, 部長
1986 – 1987: 癌研究所, 部長
1986: 癌研究会, その他, 研究員
1985: (財)癌研究会, その他, 研究員 Less
Review Section/Research Field
Except Principal Investigator
Molecular biology / Biological Sciences / Public health/Health science / Neurology
Keywords
Principal Investigator
ATL / HTLV-1 / 転写活性化 / 転写因子 / 成人T細胞白血病 / RNAプロセシング / 遺伝子発現 / ヒト白血病ウイルス / レトロウイルス / ヒト白血病ウィルス … More / ウイルス増殖 / 白血病 / 転写制御因子 / tax / rex / エンハンサ-結合蛋白 / HTLVー1 / ウィルス増殖 / エイズ / HIV / SIV / rex遺伝子 / Gag蛋白質 / Env蛋白質 / 進化速度 / キメラ粒子 / HTLV‐1 / ヒトT細胞白血病 / 転写調節 / 遺伝子発現活性化 / 転写制御 / ヒト白血病 / 細胞増殖 / 先端的研究 / 細胞接着 / がん遺伝子 / シグナル伝達 / 細胞死 / 腫瘍血管 / 薬剤耐性 / がん研究の推進 / 細胞周期 / 細胞周期阻害因子 / ウイルス発がん / 白血病ウイルス / レトロウィルス / 遺伝子発現の活性化 / 転写エンハンサー / HTLV / トランス活性化因子 / 発癌機構 / インターロイキン-2 / HTLV増殖機構 / HTLVワクチン / トランス作用 / インターロイキンー2受容体 … More
Except Principal Investigator
ゲノム構造解析 / ゲノム機能解析 / DNA解析技術 / がん / ヒト・ゲノム / cDNA / モデル生物 / 生物情報科学 / 塩基配列決定 / HIV / バイオサイエンス / 総括班 / エイズ / HAM / がん遺伝子 / がん抑制遺伝子 / Cancer / rev遺伝子 / HTLVーI / neurotropism / ATL / in situ hybridization / SIV / シンポジウム / 遺伝子 / レトロウイルス / ヒトゲノム / ウイルス発がん / 大腸がん / 口腔がん / Tsc-2 / 発がん / tat遺伝子 / vif遺伝子 / vpr遺伝子 / HIV様粒子 / CD_4 / 組換えワクチニア / gag蛋白質 / nef蛋白質 / CD4 / 血友病 / 免疫不全 / In situ hybridization / immunohistochemistry / Neurotropism / Polymelase chain reaction / 重点領域研究 / RNAレプリコン / 組織作り / ニュ-スレタ- / ポリオウイルス / インフルエンザウイルス / パラミキソウイルス / 文部省がん研究 / 成果とりまとめ / cancer research / steering / support / project / cohort / ヒトゲノム計画 / 情報科学 / シークエンス / 実験モデル生物 / 国際協力 / 疾患関連遺伝子 / ゲノムワイド関連解析 / ヒトゲノム配列再解析 / メディカルインフォマティクス / 微生物ゲノム / 産業微生物ゲノム / ゲノム / 臨床 / 微生物 / 社会医学 / 分子遺伝学 / 多型解析 / 有用微生物 / 病原微生物 / ゲノムインフォーマティック / 生命倫理 / 遺伝医学 / ゲノムインフォーマティックス / AIDS / HTLV-1 / IL-2受容体 / p40 / pX遺伝子 / STLV-1 / 多クローン性B細胞活性化 / ガン / バイオサインス / 調査研究 / cDNAプロジェクト / 大量情報処理 / ヒトゲノム研究 / ヒトゲノム解析 / cDNAライブラリ- / 大量生物遺伝情報の科学 / 各種生物ゲノム / 研究環境・研究体制 / 将来計画策定 / Human Genome / proposals / physical mapping / cDNA analyses / DNA technologies / informatics / co-ordination / 研究情報交換 / 発がんプロモーター / がん細胞 / 増殖制御 / 転写調節 / がん研究 / 研究交流 / 北米 / 研究室訪問 / 研究集会 / Information exchange / Oncogene / Tumor virus / Tumor promoter / Tumor suppressor gene / Cancer cells / Growth control / Transcriptional regulation / 物理的地図 / 遺伝的地図 / 国際学術 / 海外派遣 / 癌 / 細胞社会学 / シグナル伝達 / 細胞周期 / 薬品設計 / 遺伝子治療 / ウイルス発癌 / 細胞接着 / 癌治療 / 化学発癌 / 情報交換 / ドラッグデザイン / 癌遺伝子治療 / 癌化学療法 / 細胞増殖 / International Scientific Research / Information Exchange / Signal Transduction / Cell Cycle / Cell Adhesion / Drug Design / Gene Therapy / 胃がん / 食道がん / 肝がん / 皮膚がん / 中国 / 東南アジア / 中南米 / EBウイルス / フランス / ギリシャ / マレーシア / インドネシア / 肺がん / ホンコン / Stomach cancer / Esophageal cancer / Liver cancer / Skin cancer / China / South-East Asia / Central-South America / ゲノム安定性 / 細胞周期制御の破綻 / ヒストンアセチル化 / ヒストン脱アセチル化 / EBVと発がん / 可変型遺伝子トラップ法 / Cajal細胞 / がんの疫学 / 化学発がん / 放射線発がん / 発がん感受性 / 総括班会議 / 計画研究 / 進捗状況報告会 / 肝炎ウイルス検討会 / 研究(1) / 研究(2) / 検討班 / 「発がん」領域 / 重点シンポジウム / ワークショップ / 総合がん総括班 / 計画研究設定 / 留保金の使途 / 将来検討会 / genomic stability / dysregulation of cell cycle regulation / histone acetylation / histone deacetylation / EBV and gastric cancer / gene trap method / Cajal cell / ゲノム研究 / ゲノム情報解析 / 枯草菌ゲノム解析 / 酵母ゲノム / データベース / Genome research / Structural analyzes / Functional analysis / Genome informatics / Human genome / Analysis of B.subtilis / Yeast genome / Database / 肝内胆管癌 / ウェルナー症候群 / 血清エストロゲン値 / アジア / アメリカ / ウェルナ-症候群 / 東アジア / 南アジア / Cholangiocellular Carcinoma / Oral squarmous cell Carcinomas / Werner syndrome / Colorectal Cancer / Aerum estrogen / Asai / America / MS / HTLV-I / 多発性硬化症 / 脱髄性疾患 / 脊髄痙性痳痺 / Multiple sclerosis / HTLV-I associated myelopathy / ヒトレトロウイルス / ヒトがん遺伝子 / DNA修復 / サイトカイン / 増殖因子 / International Exchange Program / Human Gene Mapping / Oncogenes / Tumor Suppressor Genes / Cytokines / Growth Factors / French-Japanese collaborative programe in cancer research / German-Japanese collaborative program in cancer research Less
  • Research Projects

    (41 results)
  • Research Products

    (2 results)
  • Co-Researchers

    (190 People)
  •  Applied Genomics

    • Principal Investigator
      TSUJI Shoji
    • Project Period (FY)
      2004 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  がん研究の総合的推進に係る研究

    • Principal Investigator
      KITAGAWA Tomoyuki
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Japanese Foundation For Cancer Research
  •  がんの戦略的先端研究Principal Investigator

    • Principal Investigator
      渋谷 正史, 吉田 光昭
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  HTLV-1による遺伝子発現と細胞増殖の脱制御の研究Principal Investigator

    • Principal Investigator
      吉田 光昭
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  Planning-Coordination Committe on Special Cancer Research

    • Principal Investigator
      OHNO Yoshiyuki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Public health/Health science
    • Research Institution
      NAGOYA UNIVERSITY
  •  ヒト・ゲノム解析の新しい戦略に関する総合研究

    • Principal Investigator
      榊 佳之
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Molecular biology
    • Research Institution
      The University of Tokyo
  •  Japan-French Joint Research on Genome

    • Principal Investigator
      MATSUBARA Kenichi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Molecular biology
    • Research Institution
      International Institute for Advanced Studies
      Osaka University
  •  Information Exchange on Cancer Research with North American

    • Principal Investigator
      YAMAMOTO Tadashi
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      The University of Tokyo
  •  General Studies on Special Cancer Research

    • Principal Investigator
      TOMINAGA Suketami
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Aichi Cancer Center Research Institute
  •  Basic Research of carcinogenesis and cancer prevention (carcinogenesis)

    • Principal Investigator
      ITO Yoshiaki
    • Project Period (FY)
      1994 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Institute for Virus Research, Kyoto University
  •  ヒト白血病ウイルスを用いた遺伝子の発現制御とATL発症機構の研究Principal Investigator

    • Principal Investigator
      吉田 光昭
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  エイズの総合的基礎研究 柱1.HIVの構造と機能に関する研究Principal Investigator

    • Principal Investigator
      吉田 光昭
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  ヒト白血病ウイルスを用いた遺伝子の発現制御とATL発症機構の研究Principal Investigator

    • Principal Investigator
      吉田 光昭
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  RNAレプリコン

    • Principal Investigator
      野本 明男
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Institution
      The University of Tokyo
  •  ヒト・ゲノム解析研究

    • Principal Investigator
      MATSUBARA Kenichi
    • Project Period (FY)
      1991 – 1995
    • Research Category
      Grant-in-Aid for Creative Basic Research
    • Research Institution
      Osaka University
  •  ヒト・ゲノム解析研究

    • Principal Investigator
      松原 謙一
    • Project Period (FY)
      1991 – 1995
    • Research Category
      Grant-in-Aid for Creative Basic Research
    • Research Institution
      Osaka University
  •  ヒト・ゲノム解析研究

    • Principal Investigator
      松原 謙一
    • Project Period (FY)
      1991 – 1995
    • Research Category
      Grant-in-Aid for Creative Basic Research
    • Research Institution
      Osaka University
  •  Information Exchange on Cancer Research with North American Countries.

    • Principal Investigator
      YAMAGUCHI Nobuo
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Institute of Medical Science, University of Tokyo
  •  ヒト・ゲノム解析研究

    • Principal Investigator
      松原 謙一
    • Project Period (FY)
      1991 – 1995
    • Research Category
      Grant-in-Aid for Creative Basic Research
    • Research Institution
      Osaka University
  •  ヒト・ゲノム解析研究

    • Principal Investigator
      松原 謙一
    • Project Period (FY)
      1991 – 1995
    • Research Category
      Grant-in-Aid for Creative Basic Research
    • Research Institution
      Osaka University
  •  HTLVーIのneurotropismに関する研究(特にATLとHAMの病理組織をもちいたin situ hybridizationによるvirusの検索)

    • Principal Investigator
      OSAME Mitsuhiro
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kagoshima University
  •  エイズの総合的基礎研究 柱1.HIVの構造と機能に関する研究

    • Principal Investigator
      渋田 博
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  エイズの総合的基礎研究

    • Principal Investigator
      TAKATSUKI Kiyoshi
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  バイオサイエンスの進展に基づくがんの重点研究

    • Principal Investigator
      豊島 久真男
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  ヒト白血病ウィルスを用いた遺伝子の発現制御とATL発症機構の研究Principal Investigator

    • Principal Investigator
      吉田 光昭
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  HTLV-Iのneurotropismに関する研究(特にATLとHAMの病態組織をもちいたin situ liybridization によるvirusの検索)

    • Principal Investigator
      納 光弘
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kagoshima University
  •  バイオサイエンスの進展に基づくがんの重点研究

    • Principal Investigator
      豊島 久真男
    • Project Period (FY)
      1990 – 1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  バイオサイエンスの進展に基づくがんの重点研究

    • Principal Investigator
      豊島 久真男
    • Project Period (FY)
      1990 – 1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  バイオサイエンスの進展に基づくがんの重点研究

    • Principal Investigator
      TOYOSHIMA Kumao
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  ヒト白血病ウイルスの遺伝子発現と成人T細胞白血病の発症機構Principal Investigator

    • Principal Investigator
      吉田 光昭
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research
  •  エイズの総合的基礎研究 柱1、HIVの構造と機能に関する研究

    • Principal Investigator
      渋田 博
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Studies with Promotion of Human Genome Programe

    • Principal Investigator
      MATSUBARA Kenichi
    • Project Period (FY)
      1989 – 1990
    • Research Institution
      Osaka University
  •  バイオサイエンスの進展に基づくがんの充填研究(総括班)

    • Principal Investigator
      豊島 久真男
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Cooperation and Information Exchange with European Countries

    • Principal Investigator
      KUROKI Toshio
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Institute of Medical Science, University of Tokyo
  •  バイオサイエンスの進展に基づくがんの重点研究

    • Principal Investigator
      豊島 久真男
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  ヒト白血病ウイルスの遺伝子発現と成人T細胞白血病の発症機構Principal Investigator

    • Principal Investigator
      吉田 光昭
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research
  •  アメリカ大陸を中心としてがん研究先進グループとの研究交流

    • Principal Investigator
      河井 貞明
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Overseas Scientific Research
    • Research Institution
      The University of Tokyo
  •  On the etiology of multiple sclerosis;Search for retroviruses as a causative agent.

    • Principal Investigator
      IWASAKI Yuzo
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Neurology
    • Research Institution
      TOHOKU UNIVERSITY
  •  ヒト白血病ウイルス(HTLV)の発癌機構及び感染の診断予防に関する基礎的研究Principal Investigator

    • Principal Investigator
      吉田 光昭
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  ヒトレトロウイルス感染リンパ球の遺伝子表現と宿主の免疫異常に関する基礎的研究

    • Principal Investigator
      白井 俊一
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Juntendo University
  •  ヒト白血病ウイルスの発癌機構および感染の診断・予防に関する基礎的研究Principal Investigator

    • Principal Investigator
      吉田 光昭
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Japanese Foundation For Cancer Research

All 2009 2007

All Journal Article

  • [Journal Article] Familial Ischemic Cerebral Small-Vessel Disease, Alopecia, and Spondylosis Caused by Mutations in the HTRA1 Gene2009

    • Author(s)
      Hara K, Shiga A, Fukutake T, Nozaki H, Miyashita A, Yokoseki A, Kawata H, Koyama A, Arima K, Takahashi T, Ikeda M, Shiota H, Tamura M, Shimoe Y, Hirayama M, Arisato T, Yanagawa S, Tanaka A, Nakano I, Ikeda S, Yoshida Y, Yamamoto T, Ikeuchi T, Kuwano R, Nishizawa M, Tsuji S, Onodera O.
    • Journal Title

      New Engl J Med 360

      Pages: 1729-1739

    • Data Source
      KAKENHI-PROJECT-16065101
  • [Journal Article] Aprataxin, causative gene product for EAOH/AOA1, repairs DNA single-strand breaks with 3 f-phosphate and 3 f-phosphoglycolate ends.2007

    • Author(s)
      Takahashi T, Tada M, Igarashi S, Koyama A, Date H, Yokoseki A, Shiga A, Yoshida Y, Tsuji S, Nishizawa M. *Onodera O.
    • Journal Title

      Nucleic Acids Res. 35

      Pages: 3797-3809

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16065101
  • 1.  NAKAMURA Yusuke (70217909)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 0 results
  • 2.  SAKAKI Yoshiyuki (10112327)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 3.  MATSUBARA Kenichi (20037394)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 4.  FUJISAWA Jun-ichi (40181341)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 5.  TOYOSHIMA Kumao (90029760)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 6.  大木 操 (00158792)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 7.  SIBUYA Masabumi (10107427)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 8.  YOSHIKAWA Hiroshi (70019876)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
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    # of Collaborated Products: 0 results
  • 181.  SAIDA Takahiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 182.  伊藤 道恭
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 183.  GUELLAEN GEO
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 184.  JORDAN BERTR
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 185.  DUJON BERNAR
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 186.  ROIZES GERAR
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 187.  DANCHIN ANTO
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 188.  DELABAR JEAN
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 189.  GALIBERT FRA
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 190.  SLONIMSKI PI
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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