Uchiyama Takashi 内山卓

… Alternative Names

Researcher Number	80151900
External Links
Affiliation (Current)	2019: 京都大学, 医学研究科, 名誉教授
Affiliation (based on the past Project Information) *help	2005 – 2008: 京都大学, 医学研究科, 教授 1998 – 2003: 京都大学, 医学研究科, 教授 1998 – 1999: Graduate School of Medicine, Kyoto University, Professor, 大学院・医学研究科, 教授 1991 – 1997: 京都大学, ウイルス研究所, 教授 1996: 京都大学, ウイスル研究所, 教授 … More
Review Section/Research Field	Principal Investigator Hematology / Biological Sciences / Virology Except Principal Investigator Virology / Immunology / 内分泌・代謝学 / Hematology
Keywords	Principal Investigator ATL / OX40 / gp34 / HTLV-I / IL-2 / HIV / エイズ / HIV-1 / IL-2受容体 / インターロイキン2 … More Except Principal Investigator ATL / HIV / 遺伝子治療 / アデノウイルスベクター / HAM / 遺伝子導入 / 抗腫瘍免疫 / HTLV-I / HTLV-1 / RNA / 細胞移植 / がん / レトロウイルスベクター / SCIDマウス / SIV / Hypercalcemia in Malignancy / Cell Cycle / 癌化学療法 / FK506 / AIDS pathogenesis / IL-2受容体 / B Cell lymphoma / HIV replication / 化学発癌 / ワクチン / Ribozyme / 成人T細胞白血病 / 肝移植 / 癌 / Drug Design / ウイルスゲノム / エイズのウイルス学 / ヒトゲノム / Interleukin-10 / Tax / 国際学術 / ケモカイン受容体 / 悪性腫瘍 / 多クローン性B細胞活性化 / Thioredoxin / 宿主因子 / エイズ制御 / 遺伝子突然変異 / redox regulation / 動物モデル / 細胞周期 / ウィルス疾患 / pX遺伝子 / 細胞増殖 / Signal Transduction / 慢性関節リウマチ / HIV-1 / タイトレーションプレート / エイズの免疫学 / p40 / animal model / TRX / Parathyroid Hormone / Human genome / 癌遺伝子治療 / ドラッグデザイン / エイズ病態 / Epstein-Barr virus / マイクロウェル / リポソーム法 / OX40 / Cell Adhesion / インターロイキン2 / bispecific抗体 / ウイルス発癌 / 免疫細胞活性化 / anti HIV response / 転写活性化 / 海外派遣 / AIDS / トランスフォーメイション / 情報交換 / ウイルス病原性 / soluble CD23 / エイズ研究 / 多型性 / STLV-1 / 現状分析 / 高カルシウム血症 / AIDS病態 / 細胞侵入 / gp34 / 複製制御 / ADF / シグナル伝達 / Viral genome / 彷徨試験 / Th1 / 化学療法 / Cancer / 細胞接着 / 薬品設計 / HIV複製 / Gene Therapy / Th2 / NFーkB / ケモカイン / HTLVー1 / トランスジェニックラット / 癌治療 / Information Exchange / エイズ / リンパ芽球様細胞 / 免疫応答 / International Scientific Research / 抗HIV応答 / host factors / 抗ウイルス剤 / レトロウイルス / ウイルス疾患 / hPBL / リボザイム / 転写活性化因子 / antiviral drugs / 細胞社会学 / 転写活性因子 / EBV Less

Development of effective hematopoietic stem cell transplantation/cellular immunotherapy for adult T-cell leukemiaPrincipal Investigator
- Principal Investigator
  
  KADOWAKI Norimitsu, 内山卓
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Basic Research for AIDS controlPrincipal Investigator
- Principal Investigator
  
  UCHIYAMA Takashi
- Project Period (FY)
  2002
- Research Category
  
  特定領域研究
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Immunotherapy of hematological melignancies based on activation of innate immunity and costimulation through OX40/OX40LPrincipal Investigator
- Principal Investigator
  
  UCHIYAMA Takashi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  KYOTO UNIVERSITY
Development of novel therapies of hematologic malignancies based on the functional modulation of the OX40/gp34 systemPrincipal Investigator
- Principal Investigator
  
  UCHIYAMA Takashi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  KYOTO UNIVERSITY
Basic Research for AIDS control A02 ; Pathophysiology and immunology of HIV-1 infectionPrincipal Investigator
- Principal Investigator
  
  UCHIYAMA Takashi
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  KYOTO UNIVERSITY
Analysis of signal transduction of OX40/gp34 and its role in pathogenesis of hematologic diseasesPrincipal Investigator
- Principal Investigator
  
  UCHIYAMA Takashi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  KYOTO UNIVERSITY
ATL細胞に発現するT細胞活性化抗原OX40の病態生理学的意義
- Principal Investigator
  
  堀利行
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
エイズの基礎研究の動向調査と将来展望Principal Investigator
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kyoto University
ROLR OF OX40 IN IN VIVO CELL GROWTH AND ORGAN INFILTRATION OF ATL CELLSPrincipal Investigator
- Principal Investigator
  
  UCHIYAMA Takashi
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  KYOTO UNIVERSITY
エイズの病態と制御に関する基礎研究柱3.病態の免疫学的基盤Principal Investigator
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Pathogenesis and Control of AIDS
- Principal Investigator
  
  NAGAI Yoshiyuki
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Evaluation and application of activities of anti-HIV・1 ribozyme
- Principal Investigator
  
  HATTORI Toshio
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  KYOTO UNIVERSITY
HIV感染によるIL-2シグナル伝達異常Principal Investigator
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
造血幹細胞の自己複製を支持する新しい因子の同定と単離Principal Investigator
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
HTLV-1による細胞がん化の分子機構
- Principal Investigator
  
  菅村和夫
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
エイズ研究の現状と展望
- Principal Investigator
  
  NAGAI Yoshiyuki
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
Information Exchange on Cancer Research with North American
- Principal Investigator
  
  YAMAMOTO Tadashi
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  The University of Tokyo
Studies on the mechanism of cell growth of ATL cellsPrincipal Investigator
- Principal Investigator
  
  UCHIYAMA Takashi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  KYOTO UNIVERSITY
がんに対する細胞移植/遺伝子治療の基礎的研究
- Principal Investigator
  
  浅野茂隆
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
Scid miceを用いたB細胞リンパ腫の発症機構の解析と治療法の開発
- Principal Investigator
  
  稲本俊
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
HTLV-I感染細胞の造腫瘍性に必要な因子の解析Principal Investigator
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
HIV感染によるインターロイキン2受容体の変化Principal Investigator
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
がんに対する細胞移植/遺伝子治療の基礎的研究
- Principal Investigator
  
  浅野茂隆
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
リンパ球に発現している新しい接着因子の同定と解析Principal Investigator
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
ウィルス疾患における免疫細胞活性化異常に関する総合研究
- Principal Investigator
  
  淀井淳司
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
ILー2およびエリスロポエチンに共通するシグナル伝達機構の検索Principal Investigator
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
SCIDマウスを利用したATL細胞のin vivo増殖モデルの作製Principal Investigator
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
血球の増殖と機能分化におけるILー2とその受容体の役割Principal Investigator
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
IL-2受容体抗体を用いた免疫抑制剤の開発Principal Investigator
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
ATLにおけるIL-2受容体発現異常の研究Principal Investigator
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
ATLにおけるIL-2受容体発現異常の研究Principal Investigator
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
ATLにおけるIL-2受容体発現異常の研究Principal Investigator
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Study of T cell activation mechanismPrincipal Investigator
- Principal Investigator
  
  UCHIYAMA Takashi
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
IL-2・IL-2受容体を介するT細胞増殖機構の解析Principal Investigator
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
ヒト・リンパ球の遺伝子突然変異を指標とする変異原の検出
- Principal Investigator
  
  巽紘一
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Environmental Science
- Research Institution
  Kyoto University
抗Tac抗体を用いた成人T細胞白血病治療法の開発Principal Investigator
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
成人T細胞白血病細胞の腫瘍増殖におけるIL-2レセプターの役割Principal Investigator
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1985
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
Investigation for factors inducing hypercalcemia in malignancy
- Principal Investigator
  
  YAMAMOTO Itsuo
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Kyoto University
The function of interleukin-2 and its receptor in B cell growth and differentiationPrincipal Investigator
- Principal Investigator
  
  UCHIYAMA Takashi
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
ヒトレトロウイルス感染リンパ球の遺伝子表現と宿主の免疫異常に関する基礎的研究
- Principal Investigator
  
  白井俊一
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Juntendo University

All 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

[Book] 最新医学別冊新しい診断と治療のABC、潜伏感染ウイルスによる血液疾患ATLの発見とその後の展開.2007
- Author(s)
  内山卓、菱澤方勝
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-17016034
[Book] NIMA and NIPA in haploidentical related transplantation: The Kyoto Experience.(Immunobiology of the human MHC: Proceedings of the 13th International Histocompatibility Workshop and Conference., Volume I)2006
- Author(s)
  Ichinohe T, Uchiyama T, 他4名.
- Publisher
  International Histocompatibility Working Group Press.
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Optimal stimulation for CD70 induction on human monocyte-derived dendritic cells and the importance of CD70 in naive CD4^+ T cell differentiation2010
- Author(s)
  Arimoto-Miyamoto K, Kadowald N, Uchiyama T, et al.
- Journal Title
  
  Immunology 130
  
  Pages: 137-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Optimal stimulation for CD70 induction on human monocyte-derived dendritic cells and the importance of CD70 in naive CD4+ T cell differentiation.2010
- Author(s)
  Arimoto-Miyamoto K, Kadowaki N, Uchiyama T, 他3名.
- Journal Title
  
  Immunology 130
  
  Pages: 137-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Clinical significance of serum hepcidin levels on early infectious complications in allogeneic hematopoietic stem cell transplantation.2009
- Author(s)
  Kanda J, Ichinohe T, Ishikawa T, Uchiyama T, 他7名
- Journal Title
  
  Biol Blood Marrow Transplant 15
  
  Pages: 956-962
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Impact of ABO mismatching on the outcomes of allogeneic related and unrelated blood and marrow stem cell transplantations for hematologic malignancies: IPD-based meta-analysis of cohort studies.2009
- Author(s)
  Kanda J, Ichinohe T, Uchiyama T, 他7名
- Journal Title
  
  Transfusion 49
  
  Pages: 624-635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Successful treatment with intravenous colistin for sinusitis, orbital cellulites, and pneumonia caused by multidrug-resistant metallo-beta-lactamase-producing Pseudomonas aeruginosa in a patient with acute myeloid leukemia2009
- Author(s)
  Saito T, Ichinohe T, Ishikawa T, Uchiyama T, et al.
- Journal Title
  
  Int J Hematol 89
  
  Pages: 689-692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] 成人T細胞白血病2009
- Author(s)
  菱澤方勝、内山卓
- Journal Title
  
  医学と薬学 61
  
  Pages: 163-1691
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] The CD70-CD27 interaction during the stimulation with dendritic cells. promotes naive CD4^+ T cells to develop into T cell sproducing a broad array of immunost imulatory cytokines in humans2009
- Author(s)
  Hashimoto-Okada M, Kadowaki N, Uchiyama T, et al.
- Journal Title
  
  Int Immunol 21
  
  Pages: 891-904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Clinical significance of serum hepcidin levels on early infectious complications in allogeneic hematopoietic stem cell transplantation2009
- Author(s)
  Kanda J, Ichinohe T, Ishikawa T, Uchiyama T, et al.
- Journal Title
  
  Biol Blood Marrow Tmsplant 15
  
  Pages: 956-962
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Long-term survival after HLA-haploidentical SCT from noninherited maternal antigen-mismatched family donors: impact of chronic GVHD.2009
- Author(s)
  Kanda J, Ichinohe T, Uchiyama T, 他16名
- Journal Title
  
  Bone Marrow Transplant 44
  
  Pages: 327-329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] The CD70-CD27 interaction during the stimulation with dendritic cells promotes naive CD4+ T cells to develop into T cells producing a broad array of immunostimulatory cytokines in humans.2009
- Author(s)
  Hashimoto-Okada M, Kadowaki N, Uchiyama T, 他4名.
- Journal Title
  
  Int Immunol 21
  
  Pages: 891-904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Long-term survival after HLA-haploidentical SCT from noninherited maternal antigen-mismatched family donors : impact of chronic GVHD2009
- Author(s)
  Kanda J, Ichinohe T, Uchiyama T, et al.
- Journal Title
  
  Bone Marrow Transplant 44
  
  Pages: 327-329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Impact of ABO mismatching on the outcomes of allogeneic related and unrelated blood and marrow stem cell transplantation for hematologic malignancies : IPD-based meta-analysis of cohort studies2009
- Author(s)
  Kanda J, Ichinohe T, Uchiyama T, et al.
- Journal Title
  
  Transfusion 49
  
  Pages: 624-635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Mycophenolate mofetil combined with tacrolimus and minidose methotrexate after unrelated donor bone marrow transplantation with reduced-intensity conditioning.2009
- Author(s)
  Mizumoto C, Ichinohe T, Ishikawa T, Kadowaki N, Imada K, Hishizawa M, Hori T, Uchiyama T, 他6名.
- Journal Title
  
  Int J Hematol 89
  
  Pages: 538-545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Growth and differentiation advantages of CD4+ OX40+ T cells from allogeneic hematopoietic stem cell transplantation recipients.2008
- Author(s)
  Shindo T, Ishikawa T, Fukunaga A, Hori T, Uchiyama T.
- Journal Title
  
  Biol Blood Marrow Transplant 14
  
  Pages: 268-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Potential of dendritic cell immunotherapy for relapse after allogeneic hematopoietic stem cell transplantation, shown by WT1 peptide- and keyhole limpet hemocyanin-pulsed, donor-derived dendritic cell vaccine for acute myeloid leukemia2008
- Author(s)
  Kitawaki T, Kadowaki N, Ishikawa T. Ichinohe T, Uchiyama T, et.al.
- Journal Title
  
  Am J Hematol 83
  
  Pages: 315-317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Potential of dendritic cell immunotherapy for relapse after allogeneic hematopoietic stem cell transplantation, shown by WT1 peptide- and keyhole limpet hemocyanin-pulsed, donor-derived dendritic cell vaccine for acute myeloid leukemia.2008
- Author(s)
  Kitawaki T, Kadowaki N, Ishikawa T, Ichinohe T, Uchiyama T, 他5名
- Journal Title
  
  Am J Hematol 83
  
  Pages: 315-317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Altered homeostasis of CD4 memory T cells in allogeneic hematopoietic stem cell transplant recipients: chronic graft-versus-host disease enhances T cell differentiation and exhausts central memory T cell pool.2007
- Author(s)
  Fukunaga A, Ishikawa T, Uchiyama T, 他3名
- Journal Title
  
  Biol Blood Marrow Transplant 13
  
  Pages: 1176-1184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Cyclin-dependent kinase-like 5 is a novel target of immunotherapy in adult T cell leukemia.2007
- Author(s)
  Kawahara M, Hori T, Matsubara Y, Okawa K, Uchiyama T
- Journal Title
  
  J.Immunother. (in press)
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Cyclin-dependent kinase-like 5 is a novel target of immunotherapy in adult T cell leukemia.2007
- Author(s)
  Kawahara M, Hori T, Matsubara Y, Okawa K, Uchiyama T.
- Journal Title
  
  J Immunother 30
  
  Pages: 499-405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Involvement of 0X40 ligand+ mast cells in chronic GVHD after allogeneic hematopoietic stem cell transplantation.2007
- Author(s)
  Kotani A, Hori T, Fujita T, Kambe N, Matsumura Y, Ishikawa T, Miyachi Y, Nagai K, Tanaka Y, Uchiyama T
- Journal Title
  
  Bone Marrow Transpl. 39 (6)
  
  Pages: 373-375
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Virus-stimulated plasmacytoid dendritic cells induce CD4+ cytotoxic regulatory T cells.2006
- Author(s)
  Kawamura K, Kadowaki N, Kitawaki T, Uchiyama T
- Journal Title
  
  Blood 107
  
  Pages: 1031-1038
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Antibody responses associated with the graft-versus-leukemia effect in adult T-cell leukemia.2006
- Author(s)
  Hishizawa M, Ishikawa T, Uchiyama T, 他5名
- Journal Title
  
  Int J Hematol 83
  
  Pages: 351-355
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Virus-stimulated plasmacytoid dendritic cells induce CD4+ cytotoxic regulatory T cells.2006
- Author(s)
  Kawamura K, Kadowaki N, Kitawaki T, Uchiyama T
- Journal Title
  
  Blood 107 (3)
  
  Pages: 1031-1038
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Dendritic cells that endocytosed antigen-containing IgG-liposomes elicit effective anti-tumor immunity.2006
- Author(s)
  Kawamura K, Kadowaki N, Uchiyama T, 他8名
- Journal Title
  
  J Immunother 29
  
  Pages: 165-174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Dendritic cells that endocytosed antigen-containing IgG-liposomes elicit effective anti-tumor immunity.2006
- Author(s)
  Kawamura K, Kadowaki N, Suzuki R, Udagawa S, Kasaoka S, Utoguchi N, Kitawaki T, Sigimoto N, Okada N, Maruyama K, Uchiyama
- Journal Title
  
  J.Immunother. 29 (2)
  
  Pages: 165-174
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Evaluation of the function of human invariant NKT cells from cancer patients using α-galactosylceramide-loaded murine dendritic cells.2006
- Author(s)
  Shimizu K, Hidaka M, Kadowaki N, Makita N, Konishi N, Fujimoto K, Uchiyama T, Kawano F, Taniguchi M, Fuii S
- Journal Title
  
  J.Immunol. 177 (5)
  
  Pages: 3484-3492
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Dendritic cells that endocytosed antigen-containing IgG-liposomes elicit effective anti-tumor immunity.2006
- Author(s)
  Kawamura K, Kadowaki N, Suzuki R, Udagawa S, Kasaoka S, Utoguchi N, Kitawaki T, Sugimoto N, Okada N, Maruyama K, Uchiyama K.
- Journal Title
  
  J.Immunother. 29
  
  Pages: 165-174
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Virus-stimulated plasmacytoid dendritic cells induce CD4+ cytotoxic regulatory T cells.2006
- Author(s)
  Kawamura K, Kadowaki N, Kitawaki T, Uchiyama T.
- Journal Title
  
  Blood 107
  
  Pages: 1031-1038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Identification of HLA class I-restricted tumor-associated antigens in adult T cell leukemia cells by mass spectrometric analysis.2006
- Author(s)
  Kawahara M, Hori T, Matsubara Y, Okawa K, Uchiyama T.
- Journal Title
  
  Exp Hematol 34
  
  Pages: 512-518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Identification of HLA class I-restricted tumor-associated antigens in adult T cell leukemia cells by mass spectrometric analysis.2006
- Author(s)
  Kawahara M, Hori T, Matsubara Y, Okawa K, Uchiyama T
- Journal Title
  
  Exp.Hematol. 34 (11)
  
  Pages: 512-518
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Serological identification of adult T-cell leukaemia (ATL)-associated antigens.2005
- Author(s)
  Hishizawa M, Imada K, Sakai T, Ueda M, Hori T, Uchiyama T
- Journal Title
  
  Br J Haematol 130
  
  Pages: 382-390
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Introduction of OX40 ligand into lymphoma cells elicits anti-lymphoma immunity in vivo.2005
- Author(s)
  Kaneko H, Hori T Yanagita S, Kadowaki N, Uchiyama T
- Journal Title
  
  Exp Hematol 33
  
  Pages: 336-343
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Phenotypic and functional relationship between adult T cell leukemia cells and regulatory T cells.2005
- Author(s)
  Matsubara Y, Hori T, Morita R, Sakaguchi S, Uchiyama T
- Journal Title
  
  Leukemia 19
  
  Pages: 482-483
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Distribution and kinetics of SR PSOX/CXCL16 and CXCR6 expression on human dendritic cell subsets and CD4+ T cells.2005
- Author(s)
  Tabata S, Kadowaki N, Kitawaki T, Shimaoka T, Yonehara S, Yoshie O, Uchiyama T.
- Journal Title
  
  J Leukoc Biol 77
  
  Pages: 777-786
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Serological identification of adult T-cell leukaemia (ATL)-associated antigens.2005
- Author(s)
  Hishizawa M, Imada K, Sakai T, Ueda M, Hori T, Uchiyama T.
- Journal Title
  
  Br J Haematol 130
  
  Pages: 382-390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Phenotypic and functional relationship between adult T cell leukemia cells and regulatory T cells.2005
- Author(s)
  Matsubara Y, Hori T, Morita R, Sakaguchi S, Uchiyama T.
- Journal Title
  
  Leukemia 19
  
  Pages: 482-483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Impact of discontinuing fluoroquinolone prophylaxis after allogeneic marrow or peripheral blood SCT with myeloablative conditioning
- Author(s)
  Kanda J, Ichinohe T, Ishikawa T, Uchiyama T, et al.
- Journal Title
  
  Bone Marrow Trnsplant (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Pretransplant serum ferritin and C-reactive protein as predictive factors for early bacterial infection after allogeneic hematopoietic cell transplantation
- Author(s)
  Kanda J, Ichinohe T, Uchiyama T, Ishikawa T, et al.
- Journal Title
  
  Bone Marrow Trnsplant (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Impact of discontinuing fluoroquinolone prophylaxis after allogeneic marrow or peripheral blood SCT with myeloablative conditioning.
- Author(s)
  Kanda J, Ichinohe T, Ishikawa T, Uchiyama T, 他4名
- Journal Title
  
  Bone Marrow Transplant (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Pretransplant serum ferritin and C-reactive protein as predictive factors for early bacterial infection after allogeneic hematopoietic cell transplantation.
- Author(s)
  Kanda J, Ichinohe T, Uchiyama T, Ishikawa T, 他7名
- Journal Title
  
  Bone Marrow Transplant (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Transplantation of allogeneic hematopoietic stem cells for adult T-cell leukemia: a nationwide retrospective study.
- Author(s)
  Hishizawa M, Kanda J, Ichinohe T, Uchiyama T, 他21名.
- Journal Title
  
  Blood (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] 高齢者AMLに対する樹状細胞を用いた細胞免疫療法の臨床試験2010
- Author(s)
  北脇年雄, 門脇則光, 石川隆之, 内山卓, 他
- Organizer
  第32回日本造血細胞移植学会総会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] 同種造血幹細胞移植後早期における一般細菌感染症の危険因子の検討.2010
- Author(s)
  諫田淳也、一戸辰夫、内山卓、石川隆之, 他7名
- Organizer
  第32回日本造血細胞移植学会総会.
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] 高齢者AMLに対する樹状細胞を用いた細胞免疫療法の臨床試験.2010
- Author(s)
  北脇年雄, 門脇則光, 石川隆之, 内山卓, 他12名
- Organizer
  第32回日本造血細胞移植学会総会.
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] アポトーシス誘導自己白血病細胞を貪食させた樹状細胞を用いた高齢者急性骨髄性白血病に対する細胞免疫療法の第I/IIa相臨床試験2009
- Author(s)
  北脇年雄, 門脇則光, 石川隆之, 内山卓, 他
- Organizer
  第13回日本がん免疫学会総会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] 当院における成人T細胞白血病症例の後方視的解析2009
- Author(s)
  内山達樹、菱澤方勝、一戸辰夫、門脇則光、石川隆之、内山卓, 他7名
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] アポトーシス誘導自己白血病細胞を食食させた樹状細胞による高齢者AMLに対する細胞免疫療法の臨床試験2009
- Author(s)
  北脇年雄, 門脇則光, 石川隆之, 内山卓, 他
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] 骨髄破壊的前処置を用いた同種骨髄・末梢血幹細胞移植における抗菌薬予防投与の再評価.2009
- Author(s)
  諫田淳也、一戸辰夫、石川隆之、内山卓, 他4名
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] プロテアソーム阻害薬ボルテゾミブによるヒト樹状細胞における核酸認識TLRシグナルの抑制機構2009
- Author(s)
  平井麻起子、門脇則光、内山卓, 他
- Organizer
  第13回日本がん免疫学会総会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] Clinical Significance of Severity and Subcategory of Chronic GVHD Evaluated by NIH Consensus Criteria2009
- Author(s)
  Sato T, Ichinohe T, Ishikawa T, Uchiyama T, et al.
- Organizer
  51th American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] Activated CD4+ T cells are protected from NK cell-mediated cytolysis through the induction of HLA-E.2009
- Author(s)
  鷹尾珠美子、石川隆之、山下浩平、内山卓
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] Reappraisal of bacterial prophylaxis in allogeneic marrow or peripheral blood stem cell transplantation after myeloablative conditionings.2009
- Author(s)
  Kanda J, Ichinohe T, Ishikawa T, Uchiyama T, 他4名
- Organizer
  35th Annual Meeting of the European Group for Blood and Marrow Transplantation
- Place of Presentation
  Goteborg, Sweden
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] アポトーシス誘導自己白血病細胞を貪食させた樹状細胞による高齢者急性骨髄性白血病に対する細胞免疫療法の臨床試験.2009
- Author(s)
  北脇年雄, 門脇則光, 石川隆之, 内山卓, 他9名
- Organizer
  第39回日本免疫学会学術集会.
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] プロテアソーム阻害薬ボルテゾミプによる核酸認識TLRシグナルの抑制機構2009
- Author(s)
  平井麻起子、門脇則光、内山卓, 他
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] プロテアソーム阻害薬ボルテゾミブのヒト樹状細胞における核酸認謝Toll様受容体シグナルに対する抑制機構2009
- Author(s)
  平井麻起子、門脇則光、北脇年雄、内山卓
- Organizer
  第39回日本免疫学会学術集会
- Place of Presentation
  大坂
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] アポトーシス誘導自己白血病細胞を貪食させた樹状細胞による高齢者急性骨髄性白血病に対する細胞免疫療法の臨床試験2009
- Author(s)
  北脇年雄, 門脇則光, 石川隆之, 内山卓, 他
- Organizer
  第39回日本免疫学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] Clinical Significance of Severity and Subcategory of Chronic GVHD Evaluated by NIH Consensus Criteria.2009
- Author(s)
  Sato T, Ichinohe T, Ishikawa T, Uchiyama T, 他3名
- Organizer
  1th American Society of Hematology Annual Meeting and Exposition.
- Place of Presentation
  New Orleans, USA.
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] 自己白血病細胞を貧食した樹状細胞による高齢者AMLに対する細胞免疫療法2008
- Author(s)
  北脇年雄, 門脇則光, 石川隆之, 内山卓、他
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] 自己白血病細胞を貪食した樹状細胞による高齢者AMLに対する細胞免疫療法.2008
- Author(s)
  北脇年雄, 門脇則光, 石川隆之, 内山卓, 他9名
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] 成人T細胞白血病/リンパ腫に対する同種造血幹細胞移植～幹細胞源による比較.2008
- Author(s)
  諫田淳也、菱澤方勝、内山卓, 他17名
- Organizer
  第30回日本造血細胞移植学会総会.
- Place of Presentation
  大阪
- Year and Date
  2008-03-01
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] A proteasome inhibitor bortezomib suppresses the immunostimulatory activity of human plasmacytoid and myeloid dendritic cells2008
- Author(s)
  Hirai M, Kadowaki N, Uchiyama T, et.al.
- Organizer
  The 10th International Symposium on Dendritic Cells
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] Reactivation of human herpes virus 6 (HHV6) during hematopoietic stem cell transplantation: risk factor analysis of HHV6 encephalitis and survival.2008
- Author(s)
  Shimazu Y, Ishikawa T, Ichinohe T, Uchiyama T, 他3名
- Organizer
  50th Annual Meeting of the American Society of Hematology
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] Allografting for Adult T-Cell Leukemia/Lymphoma: a Nationwide Retrospective Analysis.2007
- Author(s)
  Hishizawa M, Uchiyama T, 他21名.
- Organizer
  Forty-ninth Annual Meeting of American Society of Hematology
- Place of Presentation
  Atlanta, USA.
- Year and Date
  2007-12-10
- Data Source
  KAKENHI-PROJECT-17016034
[Presentation] 同種造血幹細胞移植後の急性骨髄性白血病再発に対するWT1ペプチドパルス・ドナー由来樹状細胞療法。2006
- Author(s)
  北脇年雄, 門脇則光, 石川隆之, 一戸辰夫, 内山卓, 他5名
- Organizer
  第68回日本血液学会・第48回日本臨床血液学会合同総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-17016034

1. HORI Toshiyuki (70243102)

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73. 永田宏次 (30280788)

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74. 中畑龍俊 (20110744)

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75. 千田和広 (00192188)

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Uchiyama Takashi 内山 卓

内山 卓 ウチヤマ タカシ

UCHIYAMA Takashi 内山 卓

Research Projects

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Development of effective hematopoietic stem cell transplantation/cellular immunotherapy for adult T-cell leukemiaPrincipal Investigator

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Basic Research for AIDS controlPrincipal Investigator

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Immunotherapy of hematological melignancies based on activation of innate immunity and costimulation through OX40/OX40LPrincipal Investigator

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Development of novel therapies of hematologic malignancies based on the functional modulation of the OX40/gp34 systemPrincipal Investigator

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Basic Research for AIDS control A02 ; Pathophysiology and immunology of HIV-1 infectionPrincipal Investigator

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Analysis of signal transduction of OX40/gp34 and its role in pathogenesis of hematologic diseasesPrincipal Investigator

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エイズの基礎研究の動向調査と将来展望Principal Investigator

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ROLR OF OX40 IN IN VIVO CELL GROWTH AND ORGAN INFILTRATION OF ATL CELLSPrincipal Investigator

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エイズの病態と制御に関する基礎研究 柱3.病態の免疫学的基盤Principal Investigator

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HIV感染によるIL-2シグナル伝達異常Principal Investigator

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造血幹細胞の自己複製を支持する新しい因子の同定と単離Principal Investigator

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Uchiyama Takashi 内山卓

内山卓ウチヤマタカシ

UCHIYAMA Takashi 内山卓

エイズの病態と制御に関する基礎研究柱3.病態の免疫学的基盤Principal Investigator