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Kiyono Hiroshi  清野 宏

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… Alternative Names

清野 宏  キヨノ ヒロシ

KIYONO Hiroshi  清野 宏

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Researcher Number 10271032
Affiliation (Current) 2019: 東京大学, 医科学研究所, 特任教授
Affiliation (based on the past Project Information) *help 2018 – 2019: 東京大学, 医科学研究所, 特任教授
2002 – 2016: The Institute of Medical Science The University of Tokyo, Professor, 医科学研究所, 教授
2007: 東大, 医科学研究所, 教授
2005: Tokyo University, Graduate School of Medicine, Professor, 医学研究科, 教授
2004 – 2005: 東京大学, 医学系研究科, 教授
1995 – 2003: 大阪大学, 微生物病研究所, 教授
1998 – 2002: 大阪大学, 微生物研究所, 教授
Review Section/Research Field
Principal Investigator
Biological Sciences / Immunology / Immunology / Medium-sized Section 53:Organ-based internal medicine and related fields / Broad Section I
Except Principal Investigator
Gastroenterology / 内科学一般 / Biological Sciences / Applied optics/Quantum optical engineering / Immunology … More / Immunology / Otorhinolaryngology / Human pathology / General surgery / Anesthesiology/Resuscitation studies / Gastroenterology / Digestive surgery / Digestive surgery Less
Keywords
Principal Investigator
粘膜免疫 / 粘膜ワクチン / IgA / 経鼻ワクチン / 分泌型IgA / 粘膜アジュバント / 経口ワクチン / 粘膜免疫調節因子 / AIDSワクチン / 経口免疫 … More / 粘膜免疫機構 / Th2型細胞 / HIVワクチン / 胚中心 / 共生細菌 / パイエル板 / フコシル化 / M細胞 / 上皮細胞 / 性感染症 / IL-12 / Mucosal immune system / 間葉系細胞 / 炎症性腸疾患 / 粘膜系Th1 / HIV / LT / 粘膜系Th1型 / Th2型 / AIDSと粘膜免疫 / キメラ型無毒化毒素 / 鼻咽腔関連リンパ組織 / バイエル板 / リンフォイドケモカイン / 原基 / Alcaligenes / 孤立リンパ濾胞 / Tfh細胞 / 腸管IgA / 濾胞性ヘルパーT細胞 / Foxp3+制御性T細胞 / PD-1 / 絨毛上皮細胞 / 自然免疫担当細胞 / 濾胞性樹状細胞 / レチノイン酸 / Alcaligrnes / 孤立性リンパ濾胞 / FoxP3^+制御性T細胞 / 樹状細胞 / 粘膜免役 / 抗原取り込み / UEA-1 / HSV2 / アジュバント / 生殖免疫 / ワクチン / ケモカイン / 細胞遊走 / 経鼻免疫 / 膣粘膜感染症 / 膣粘膜指向性関連分子 / エフェクターT細胞 / 経鼻・経鼻免疫 / 粘膜指向性 / Th1型細胞 / 無毒化リコンビナントサルモネラ菌 / IFN-γ遺伝子欠損マウス / Th1型 / Th2型応答 / レベル2 Th2型 / Mucosal Immune System / Mucosal Vaccine / Mucosal Intranet / Mucosal Modulator / Mucosal Adjuvant / Mucosal Th1 / Mucosal Th2 / CMIS / B-1細胞 / IL-5 / IL-15 / CMIS独立型 / 粘膜細胞イントラネット / 粘膜細胞間インターネット / 粘膜細胞間イントラネット / 粘膜誘導型寛容 / 経口免疫寛容 / 粘膜系γδT細胞 / TCRδ遺伝子欠損マウス / IL-10 / 上皮細胞間リンパ球 / コレラ毒素 / IL-7 / IL-7R / γδT細胞 / Mucosal intranet / Epithelial cell / Mucosal T cells / Peyer's patch / B-1 / B-2 cells / 粘膜免疫システム / 無毒化変異型CT / 粘膜アジュバンド / Mucosal vaccine / Secretory IgA / Mucosal adjuvant / mutant CT / Mucosal cytokine / 腸管粘膜 / パネート細胞 / 階層的粘膜支持連関システム / 臓器連関 / 蠕動運動 / 抗菌ペプチド … More
Except Principal Investigator
粘膜免疫 / サイトカイン / 炎症性腸疾患 / IL-7 / 免疫病 / T細胞 / 転写因子 / 食物アレルギー / inflammatory bowel disease / HIV / CXCR4 / CTL / アポトーシス / シグナル伝達 / 自然免疫 / 疫学 / 免疫学 / パイエル板 / ILISPOT / IDIP / 蛍光色素 / 粘膜免疫機構 / cytokine / Fluorescent dye / 免疫検査 / Immunoassay / HIV-1 / AIDS / mucosal immunity / NALT / IgA / mucosal immune system / food allergy / Bacteroides vulgatus / HVJ-liposome / 腸管免疫 / 再生医療 / 腸管上皮細胞 / 骨髄細胞 / 慢性大腸炎 / regenerative medicine / intestinal epithelial cell / bone marrow cell / FTY720 / IL-10^<- / ->マウス / Th1 / Atoh1 / Hath1 / Wnt / Notch / エイズ / CD26 / HHV8 / Fas / CXCR-4 / ヒト免疫不全ウイルス / 免疫不全 / 細胞傷害性T細胞 / インターロイキン2 / インターロイキン8 / エイズリンパ腫 / 自己免疫疾患 / 慢性炎症 / 原発性免疫不全症 / 免疫寛容の破綻 / チロシンキナーゼ / 免疫病の修復 / 免疫不全症 / 自己免疫症患 / ケモカイン / 自己抗原 / Btk / GPIアンカー / PIG-V / Sema4A / sema6D / TLR / MyD88非依存症性経路 / gH-gL-gO / LANA / 感染症 / ヒトヘルペスウイルス6 / セマフォリン / Toll様レセプター / インターロイキン6 / ヒトヘルペルウイルス6 / CD40 / ヒトヘルペスウイルス / 感染免疫 / ノックアウトマウス / 早期誘導反応 / 後期適応免疫 / Helicobacter pylori / 免疫 / 感染宿主 / 人種差 / 遺伝子型 / H.pylori / 病理 / 消化器病学 / 生体防御 / 免疫応答 / 生体恒常性 / 自己認識 / 免疫制御 / 胸腺 / 自己免疫病 / 炎症 / がん / 免疫系自己 / 自己識別 / 免疫病態 / 自己寛容 / 免疫組織 / がん免疫 / 獲得免疫 / 免疫老化 / 白血病 / アナジー / G蛋白 / 自己免疫 / 小腸粘膜傷害 / NSAID / 樹状細胞 / NSAID / 小腸粘膜障害 / NSAIDs / CD103陽性樹状細胞 / NSAIDs / 免疫検査法 / 自動化 / パターン認識 / レーザー / バイオメディカル / ILISPOT法 / 抗原特異抗体 / 免疫担当細胞 / immunoassay / automation / pattern recognition / laser / 免疫寛容 / B細胞 / 発生工学 / ポリコ-ム遺伝子 / 水晶体特異的遺伝子発現 / 有機リン系農薬センサー / T cell / Immunological tolerance / B cell / Transgenics / Polycomb genes / Crystallin gene / Biosensor / Transcriptional factor / 自動化細胞計測 / 画像処理 / 含フッ素化合物 / 白色光レーザ / Automated measurement of cell / Cytokin / Image processing / Fluorine-containing compound / White light laser / CCR5 / SDF-1 / dendritic cells / mucosol immunity / gp120 / V3ループ / エイズワクチン / Pathophysiology / Immune response / AIDS Control / Chemokine / Chemokine Receptor / ワクチン / 経鼻免疫 / インフルエンザ菌 / 肺炎球菌 / RSウイルス / 鼻粘膜 / 中耳粘膜 / マウス / CD4^+T細胞 / P6 / Intranasal immunization / vaccine / Mucosal immune system / Haemophilus influenzae / Streptococcus pneumoniae / RS virue / 経口免疫 / 神経内分泌系 / 食物アレルギーモデルマウス / 上皮細胞間リンパ球 / 鶏卵アレルギー / 神経ペプチド / クリプトパッチ / 消化管アレルギー / 炎症性腸管障害 / 卵白アルブミン / ニューロペプチド / 好中球 / CD4_+T細胞 / 消化管粘膜障害 / 炎症性粘膜障害 / 経口免疫寛容 / 粘膜ワクチン / トランスジェニックマウス / oral immunization / neuroendocrine system / animal model for food allergy / intraepithelial lymphocyte / egg white allergy / TCRα鎖欠損マウス / 食餌抗原 / 成分栄養 / 腸内細菌叢 / TCR α- / - mice / elemental diet / enteric flora / 含フッ素置換基 / カラーセンタレーザ / 赤外スペクトル / 赤外ラマン分光 / 赤外吸収 / 炭素-フッ素結合 / Fluorine-containing substituent / Color-center laser / Infrared spectrum / Infrared Raman spectroscopy / Infrared absorption / Carbon-fluorine bond / NF-kB / デコイ型核酸 / HVJ-liposome法 / 神経因性疼痛 / 遺伝子導入 / ベクター / デコイ / 疼痛過敏 / NF-κB / decoy / heuropathic pain / IL-7レセプター / 植物アレルギー / 粘膜リンパ球 / 骨髄幹細胞 / IL-7 receptor / mucosal jmmunity / chronic cohtis / IL-10遺伝子欠損マウス / 大腸粘膜固有層リンパ球 / 腸間膜リンパ節 / 粘膜固有層 / FK506 / Interleukin-10 gene-deficient mice / Colonic lamina propria lymphocyte / Peyer's patch / Mesenteric lymph node / Lamina propria / 腸上皮細胞 / 細胞分化 / 慢性腸炎 / 消化管粘膜免疫 / 粘膜IL-7 / IL-7レセプター機構 / 腸管上皮細胞分化 / Interferon Regulatory Factor (IRF) / 骨髄細胞transdifferentiation / Il-7レセプター / cell differentiation / chronic colitis / transcriptional factor / IL-10ノックアウトマウス / Bcl-2トランスジェニックマウス / 腸管上皮 / 消化管上皮 / Inflammatory Bowel Disease / IL-10 knock out mouse / Bcl transgenic mouse / Intestinal epithelium / apoptosis / 再生医学 / トランスレーショナルリサーチ / 発生・分化 / Wntシグナル / Notchシグナル / 細胞内シグナル伝達 / ユビキチン-プロテアソーム / 腸管分化 / Hath-1 / Differentiation / Regenerative medicine / Translational research / Signal transduction Less
  • Research Projects

    (40 results)
  • Research Products

    (266 results)
  • Co-Researchers

    (157 People)
  •  消化管の階層的粘膜支持連関システムによる粘膜防御機構の解明Principal InvestigatorOngoing

    • Principal Investigator
      清野 宏
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      The University of Tokyo
  •  Multi Regulatory System for Gut Homeostasis and InflammationPrincipal InvestigatorOngoing

    • Principal Investigator
      清野 宏
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section I
    • Research Institution
      The University of Tokyo
  •  Immunological crosstalk between nasal and reproductive mucosal tissuePrincipal Investigator

    • Principal Investigator
      Kiyono Hiroshi
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Immunology
    • Research Institution
      The University of Tokyo
  •  顎顔面免疫と生殖器免疫のクロストークPrincipal Investigator

    • Principal Investigator
      清野 宏
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      The University of Tokyo
  •  Investigation of the role of mucosal inductive site and indigenous bacteria on the NSAID-induced enteropathy

    • Principal Investigator
      IIJIMA Hideki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Osaka University
  •  Analysis of antigen-uptake network at mucosal epithelial layerPrincipal Investigator

    • Principal Investigator
      KIYONO Hiroshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      The University of Tokyo
  •  Mucosal Immunology and self‐discriminationPrincipal Investigator

    • Principal Investigator
      KIYONO Hiroshi
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Immunological Self Recognition and its Disorders

    • Principal Investigator
      MINATO Nagahiro
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  生体防御と免疫病制御の統合的パラダイム

    • Principal Investigator
      MINATO Nagahiro
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Kyoto University
  •  粘膜免疫監視の場としてのGALT・NALTを介した免疫制御誘導の解明Principal Investigator

    • Principal Investigator
      清野 宏
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Identification of the crosstalk between Notch signaling and Wnt signaling in the differentiation of the intestinal epithelial cells.

    • Principal Investigator
      WATANABE Mamoru
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  エイズ粘膜ワクチン開発へ向けて:HIV特異的分泌型IgA誘導システムの開発Principal Investigator

    • Principal Investigator
      清野 宏
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  粘膜免疫監視の場としてのGALT・NALTを介した免疫制御誘導の解明Principal Investigator

    • Principal Investigator
      清野 宏
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Regulation of Intestinal Mucosal Immunity in a Mouse Model on Inflammatory Bowel Disease

    • Principal Investigator
      ITO Toshinori
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Osaka University
  •  HIV特異的分泌型IgA誘導粘膜ワクチン開発へ向けての基礎研究Principal Investigator

    • Principal Investigator
      清野 宏
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Development of a novel therapy for the treatment of chronic colitis based on the manipulation of mucosal immune response and the clarification of tissue specific system for epithelial regeneration.

    • Principal Investigator
      WATANABE Mamoru
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  粘膜ワクチンへの基礎研究:HIV特異的分泌型IgA誘導システムの開発Principal Investigator

    • Principal Investigator
      清野 宏
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  粘膜ワクチンへの基礎研究:HIV特異的分泌型IgA誘導型アジュバント開発Principal Investigator

    • Principal Investigator
      清野 宏
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Elucidation of the mechanism for regurating mucosal immune response and application for the treatment of chronic colitis and food allergy.

    • Principal Investigator
      WATANABE Mamoru
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  Study of mucosal immune response in the murine model of inflammatory bowel disease -Therapeutic effect of a new immunosuppressive reagent FTY720-

    • Principal Investigator
      ITO Toshinori
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Osaka University
  •  H.pylori感染者の病型決定因子に関する集学的研究

    • Principal Investigator
      若月 芳雄
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Kyoto University
  •  Therapy of neuropathic pain by using a gene-based approach of NF-κB decoy

    • Principal Investigator
      MASHIMO Takashi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Osaka University
  •  免疫病とその修復

    • Principal Investigator
      高津 聖志
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  Application of a color-center laser to an immunoassay using an IR-Raman spectroscopy technique.

    • Principal Investigator
      KAMEMARU Shun-ichi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Applied optics/Quantum optical engineering
    • Research Institution
      Kitami Institute of Technology
  •  感染免疫の分子基盤の新展開

    • Principal Investigator
      吉開 泰信
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Nagoya University
  •  H.pylori菌感染症の病型決定因子に関する集学的研究

    • Principal Investigator
      若月 芳雄
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Kyoto University
  •  Characterization of Novel Mucosal Modulator for IgAPrincipal Investigator

    • Principal Investigator
      KIYONO Hiroshi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  Basic Research for AIDS control A02 ; Pathophysiology and immunology of HIV-1 infection

    • Principal Investigator
      UCHIYAMA Takashi
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      KYOTO UNIVERSITY
  •  The mucosal immune system of the upper respiratory tract and development of nasal vaccine for upper respiratory tract infection

    • Principal Investigator
      MOGI Goro
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Oita Medical University
  •  Establishment of disease mechanism of inflammatory and allergic disorders in the intestinal mucosa from the mucosal immune system and development for their treatments

    • Principal Investigator
      NAGURA Hiroshi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Human pathology
    • Research Institution
      Tohoku University
  •  A study of the environmental factors for the development of inflammatory bowel disease

    • Principal Investigator
      INOUE Yoshifumi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Osaka University
  •  感染症と免疫病の分子生物学と医学

    • Principal Investigator
      山西 弘一, 岸本 忠三
    • Project Period (FY)
      1997 – 2003
    • Research Category
      Grant-in-Aid for COE Research
    • Research Institution
      Osaka University
  •  Application of a whitelight laser and dye to medical treatment.

    • Principal Investigator
      KAMEMARU Shun-ichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Applied optics/Quantum optical engineering
    • Research Institution
      Kitami Institute of Technology
  •  Characterization of mucosal intranet formed by γδ/αβ T cells and epithelial cellsPrincipal Investigator

    • Principal Investigator
      KIYONO Hiroshi
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  AIDS粘膜ワクチン:Th1/Th2型細胞によるHIV特異的粘膜免疫の誘導Principal Investigator

    • Principal Investigator
      清野 宏
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Regulation of Gene Expression

    • Principal Investigator
      TANIGUCHI Masaru
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University, School of Medicine
  •  Mucosal Vaccines : Vectors and Adjuvants for Novel Th1 and Th2 cellsPrincipal Investigator

    • Principal Investigator
      KIYONO Hiroshi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Immunology
    • Research Institution
      Osaka University
  •  エイズの病態と制御に関する基礎研究 柱3.病態の免疫学的基盤

    • Principal Investigator
      UCHIYAMA Takashi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  AIDS粘膜ワクチン:Th1/Th2型細胞によるHIV特異的粘膜免疫の誘導Principal Investigator

    • Principal Investigator
      清野 宏
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Visualized measurement of cell by laser and fluorescence dye, -Its application to immunology and cancer treatment-

    • Principal Investigator
      FUJII Kanichi
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Ibaraki University

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2005 2004 Other

All Journal Article Presentation Book

  • [Book] 次世代アジュバント開発のためのメカニズム解明と安全性評価2017

    • Author(s)
      清野宏、幸 義和、中橋 理佳、畔上 達彦
    • Total Pages
      354
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Book] リンパ学会誌2016

    • Author(s)
      Nakahashi, R., Nagatake, T. and Kiyono, H.
    • Publisher
      株式会社ライフメディコム
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Book] Medical Science Digest2016

    • Author(s)
      Azegami, T. and Kiyono, H.
    • Publisher
      New Science
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Book] 粘膜免疫の最新情報2016

    • Author(s)
      Yoshihara, S. and Kiyono, H.
    • Total Pages
      5
    • Publisher
      日本口腔・咽頭科学会 事務局
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Book] 実験医学2016

    • Author(s)
      Nakahashi, R. and Kiyono, H.
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Book] 歯界展望2017年特別号2016

    • Author(s)
      Kishikawa, S. and Kiyono, H.
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Book] 化学療法の領域2016

    • Author(s)
      Kashima, K., Takeyama, N., Yuki, Y. and Kiyono, H.
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Book] 細胞工学(粘膜免疫システム)2011

    • Author(s)
      清野宏
    • Publisher
      (株)秀潤社
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Book] 臨床粘膜免疫学2010

    • Author(s)
      清野宏
    • Total Pages
      722
    • Publisher
      株式会社シナジー
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Book] 臨床粘膜免疫学2010

    • Author(s)
      清野宏
    • Total Pages
      722
    • Publisher
      (株)シナジー
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Book] 臨床粘膜免疫学2010

    • Author(s)
      清野宏
    • Total Pages
      722
    • Publisher
      株式会社シナジー
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Book] 臨床粘膜免疫学

    • Author(s)
      清野宏
    • Publisher
      (株)シナジー
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Epithelial extracellular ATP: an initiator of immunity to parasitic infections. Immunology and Cell Biolog.2017

    • Author(s)
      Nelson, S., Kiyono, H. and Kurashima, Y.
    • Journal Title

      Immunology & Cell Biology

      Volume: 95 Pages: 117-8

    • DOI
      10.1038/icb.2016.106
    • Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] Allograft inflammatory factor 1 is a regulator of transcytosis in M cells2017

    • Author(s)
      Kishikawa, S., Sato, S., Kaneto, S. Uchino, S., Kohsaka, S., Nakamura, S. and Kiyono, H.
    • Journal Title

      Nat Commun

      Volume: 8 Pages: 14509-14509

    • DOI
      10.1038/ncomms14509
    • Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-16K08836, KAKENHI-PLANNED-25117009
  • [Journal Article] Mucosal Ecological Network of Epithelium and Immune Cells for Gut Homeostasis and Tissue Healing.2017

    • Author(s)
      Kurashima, Y. and Kiyono, H.
    • Journal Title

      Annual Review of Immunology

      Volume: - Pages: 51116-52424

    • DOI
      10.1146/annurev-immunol-051116-052424
    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] MicroRNA-mediated dynamic control of mucosal immunity.2017

    • Author(s)
      Park, EJ., Shimaoka, M. and Kiyono, H.
    • Journal Title

      Int Immunol

      Volume: - Pages: 157-163

    • DOI
      10.1093/intimm/dxx019
    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-16K08581, KAKENHI-PROJECT-16K15759
  • [Journal Article] Impaired airway mucociliary function reduces antigen-specific IgA immune response to immunization with a claudin-4-targeting nasal vaccine in mice.2017

    • Author(s)
      Kunisawa, J., Yagi, K., Ikegami, K., Hamazaki, Y., Suzuki, H., Nagatake, T., Kiyono, H., Kondoh, M., Nasu, A. and Setou, M.
    • Journal Title

      Journal of Controlled Release

      Volume: -

    • Acknowledgement Compliant / Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] The spleen is the site where mast cells are induced in the development of food allergy.2017

    • Author(s)
      Toyoshima, S., Wakamatsu, E., Ishida, Y., Obata, Y., Kurashima, Y., Kiyono, H. and Abe, R.
    • Journal Title

      International Immunology

      Volume: -

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] Seed Metabolome analysis of a transgenic rice line expressing cholera toxin B-subunit.2017

    • Author(s)
      Ogawa, T., Kashima, K., Yuki, Y., Mejima, M., Kurokawa, S., Okazawa, A., Kiyono, H. and Ohta, D.
    • Journal Title

      Science Reports

      Volume: -

    • Acknowledgement Compliant / Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] Critical role of TSLP-responsive mucosal dendritic cells in the induction of nasal antigen-specific IgA response2017

    • Author(s)
      Joo,S., Fukuyama, Y., Park,E-J., Yuki, Y., Kurashima, Y., Ziegler, S.F. and Kiyono,H.
    • Journal Title

      Mucosal Immunology

      Volume: - Pages: 901-911

    • DOI
      10.1038/mi.2016.103
    • Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-16K08581
  • [Journal Article] Nanogel-based nasal ghrelin vaccine prevents obesity.2017

    • Author(s)
      Azegami, T., Yuki, Y., Sawada, S,, Mejima, M., Ishige, K., Akiyoshi, K., Itoh, H. and Kiyono H.
    • Journal Title

      Mucosal Immunology

      Volume: -

    • DOI
      10.1038/mi.2016.137
    • Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] Critical role of interleukin-4 modulating regulatory T cells for desensitization, tolerance and inflammation of food allergy.2017

    • Author(s)
      Nakajima-Adachi, H., Shibahara, K., Fujimura, Y., Takeyama, J., Hiraide, E., Kikuchi, A., Murakami, H., Hosono, A., Nochi, T., Wakatsuki, Y., Shimojo, N., Kaminogawa, S., Sato, R., Kiyono, H. and Hachimura, S.
    • Journal Title

      PLoS ONE

      Volume: 12

    • DOI
      10.1371/journal.pone.0172795
    • Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-16H06207, KAKENHI-PROJECT-26292065, KAKENHI-PROJECT-26660245, KAKENHI-PROJECT-15K07443
  • [Journal Article] E-NPP3 controls plasmacytoid dendritic cell numbers in the small intestine.2017

    • Author(s)
      Furuta, Y., Tsai, S-H., Kinoshita, M., Fujimoto, K., Okumura, R., Umemoto, E., Kurashima, Y, Kiyono, H., Kayama, H., Takeda, K.
    • Journal Title

      PLoS One

      Volume: 12

    • DOI
      10.1371/journal.pone.0172509
    • Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-15H02511, KAKENHI-PROJECT-15K15152, KAKENHI-PROJECT-16K08838
  • [Journal Article] Differential analyses of major allergen proteins in wild-type rice and rice producing a fragment of anti-rotavirus antibody.2016

    • Author(s)
      Yuki Y, Kurokawa S, Kozuka-Hata H, Tokuhara D, Mejima M, Kuroda M, Oyama M, Nishimaki-Mogami T, Teshima R, Kiyono H.
    • Journal Title

      Regul Toxicol Pharmacol.

      Volume: 76 Pages: 128-136

    • DOI
      10.1016/j.yrtph.2016.01.023
    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26505001, KAKENHI-PROJECT-23229004, KAKENHI-PLANNED-16H06578
  • [Journal Article] ISH NIA OS-02 attenuation of hypertension by less-invasive intranasal vaccination against angiotensin II type 1 receptor in spontaneously hypertensive rats.2016

    • Author(s)
      Azegami, T., Yuki, Y., Hayashi, K., Nakamura, M., Hishikawa, A., Kiyono, H. and Itoh, H.
    • Journal Title

      Journal of Hypertension

      Volume: 1 Pages: 42-42

    • Acknowledgement Compliant / Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] Epithelial glycosylation in gut homeostasis and inflammation2016

    • Author(s)
      Goto, Y., Uematsu, S. and Kiyono, H.
    • Journal Title

      Nat Immunol.

      Volume: 17 Pages: 1244-1251

    • DOI
      10.1038/ni.3587
    • Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229004, KAKENHI-PUBLICLY-15H01367, KAKENHI-PROJECT-16H06229, KAKENHI-PROJECT-15K14404
  • [Journal Article] MicroRNA-orchestrated pathophysiologic control in gut homeostasis and inflammation.2016

    • Author(s)
      Lee, J., Park, E.J. and Kiyono H.
    • Journal Title

      BMB Reports

      Volume: 49 Pages: 263-9

    • Acknowledgement Compliant / Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] A Novel Transgenic Rice-based Vaccine:2015

    • Author(s)
      Azegami, T., Itoh, H., Kiyono, H. and Yuki, Y.
    • Journal Title

      Arch. Immunol. Ther. Ex

      Volume: 63(2) Pages: 87-99

    • DOI
      10.1007/s00005-014-0303-0
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-24659203
  • [Journal Article] Comparative whole-genome analyses of selection marker–free rice-based cholera toxin B-subunit vaccine lines with wild-type lines.2015

    • Author(s)
      Kashima, K., Mejima, M., Kurokawa, S., Kuroda, M., Kiyono, H. and Yuki, Y.
    • Journal Title

      BMCGgenomics

      Volume: 48 Pages: 48-48

    • DOI
      10.1186/s12864-015-1285-y
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-24659203
  • [Journal Article] 腸管バリアとしての糖鎖修飾とその制御2015

    • Author(s)
      後藤義幸、清野宏
    • Journal Title

      実験医学

      Volume: 33(4) Pages: 544-549

    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] Nanogel-based pneumococcal surface protein A nasal vaccine induces microRNA-associated Th17 cell responses with neutralizing antibodies against Streptococcus pneumonia in macaques.2015

    • Author(s)
      Fukuyama, Y., Yuki, Y., Katakai, Y., Harada, N., Takahashi, H., Takeda, S., Mejima, M., Joo, S., Kurokawa, S., Sawada, S., Shibata, H., Park, EJ., Fujihashi., K, Briles, D., Yasutomi, Y., Tsukada, H., Akiyoshi, K., Kiyono, H.
    • Journal Title

      Mucosal Immunology

      Volume: -

    • DOI
      10.1038/mi.2015.5
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-24659203, KAKENHI-PROJECT-25670225
  • [Journal Article] Negative regulation of DSS-induced experimental colitis by PILRα2015

    • Author(s)
      Kishida, K., Kohyama, M., Kurashima, Y., Kogure, Y., Wang, J., Hirayasu, K., Suenaga, T., Kiyono, H., Kunisawa, J. and Arase, H.
    • Journal Title

      International immunology

      Volume: - Pages: 307-314

    • DOI
      10.1093/intimm/dxv004
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-23390112, KAKENHI-PLANNED-24115005, KAKENHI-PROJECT-24590584, KAKENHI-PUBLICLY-25133705, KAKENHI-PROJECT-25460565, KAKENHI-PROJECT-25670143, KAKENHI-PROJECT-26870334, KAKENHI-PROJECT-26893047
  • [Journal Article] レチノイン酸代謝による皮膚バリアの恒常性維持-線維芽細胞によるマスト細胞調節機構-2015

    • Author(s)
      佐藤健、倉島洋介、國澤純、清野宏
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 63(2) Pages: 139-145

    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] Loss of Lymph Node Fibroblastic Reticular Cells and High Endothelial Cells Is Associated with Humoral Immunodeficiency in Mouse Graft-versus-Host Disease.2015

    • Author(s)
      Suenaga, F., Ueha, S., Abe, J., Kosugi-Kanaya, M., Wang, Y., Yokoyama, A., Shono, Y., Shand, F. H., Morishita, Y., Kunisawa, J., Sato, S., Kiyono, H. and Matsushima, K.
    • Journal Title

      J Immunol.

      Volume: 194(1) Pages: 398-406

    • DOI
      10.4049/jimmunol.1401022
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-25293113, KAKENHI-PROJECT-25460491, KAKENHI-PROJECT-25860353
  • [Journal Article] The Ectoenzyme E-NPP3 Negatively Regulates ATP-Dependent Chronic Allergic Responses by Basophils and Mast Cells.2015

    • Author(s)
      Tsai, S-H., Kinoshita, M., Kusu, T., Kayama, H., Okumura, R., Ikeda, K., Shimada, Y., Takeda, A., Yoshikawa, S., Obata-Ninomiya, K., Kurashima, Y., Sato, S., Umemoto, E., Kiyono, H., Karasuyama, H. and Takeda, K.
    • Journal Title

      Immunity

      Volume: 42(2) Pages: 279-293

    • DOI
      10.1016/j.immuni.2015.01.015
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23229004, KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-24390093, KAKENHI-PROJECT-24390120, KAKENHI-PROJECT-24590252, KAKENHI-PROJECT-25860353, KAKENHI-PROJECT-26870172, KAKENHI-PROJECT-26893047
  • [Journal Article] Development of selection marker-free rice-based oral cholera toxin B-subunit vaccine and characterization of location and structure of transgene by using whole genome resequencing analysis.2015

    • Author(s)
      Mejima, M., Kashima, K., Kuroda, M., Takeyama, N., Kurokawa S., Fukuyama Y., Kiyono H., Itoh, K., Mitsui, T., and Yuki, Y.
    • Journal Title

      Plant Cell Tiss. Org. Cult.

      Volume: 120 Pages: 35-48

    • DOI
      10.1007/s11240-014-0575-4
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-24659203
  • [Journal Article] Vitamins mediate immunological homeostasis and diseases at the surface of the body.2015

    • Author(s)
      Kunisawa J. and Kiyono H.
    • Journal Title

      Endocr. Metab. Immune Disord. Drug Targets

      Volume: 15(1) Pages: 25-30

    • DOI
      10.2174/1871530314666141021114651
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] Mucosal immunosenescence in the gastrointestinal tract: A mini-review.2015

    • Author(s)
      Sato, S., Kiyono, H. and Fujihashi, K.
    • Journal Title

      Gerontology

      Volume: -

    • DOI
      10.1159/000368897
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] Vaginal memory T cells induced by intranasal vaccination are critical for protective T cell recruitment and prevention of genital HSV-2 disease.2014

    • Author(s)
      Sato, A., Suwanto, A., Okabe, M., Sato, S., Nochi, T., Imai, T., Koyanagi, N., Kunisawa, J., Kawaguchi, Y. and Kiyono, H.
    • Journal Title

      J. Virol.

      Volume: 88(23) Pages: 13699-13708

    • DOI
      10.1128/jvi.02279-14
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-25860353, KAKENHI-PROJECT-26660245
  • [Journal Article] 自然リンパ球による腸管上皮細胞の糖鎖修飾誘導・制御システム2014

    • Author(s)
      後藤義幸、清野宏
    • Journal Title

      分子消化器病

      Volume: 11(4) Pages: 86-88

    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] Skin-barrier homeostasis through Cyp26b1-mediated inhibition of ATP-dependent mast-cell activation by fibroblasts2014

    • Author(s)
      Kurashima Y, Amiya T, Fjisawa K, Shibata N, Suzuki Y, Kogure Y, Hashimoto E, Otsuka A, Kabashima K, Sato S, Sato T, Kubo M, Akira S, Miyake K, Kunisawa J, Kiyono H.
    • Journal Title

      Immunity

      Volume: 40 Pages: 530-41

    • DOI
      10.1016/j.immuni.2014.01.014
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-11J04859, KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-24249058, KAKENHI-PROJECT-24659217, KAKENHI-PUBLICLY-25116706, KAKENHI-PROJECT-25860353, KAKENHI-PROJECT-26293111, KAKENHI-PROJECT-26670241, KAKENHI-PROJECT-26893047
  • [Journal Article] 細胞外核酸を介したマスト細胞の活性化と炎症性腸疾患2014

    • Author(s)
      倉島洋介、清野宏、國澤純
    • Journal Title

      生化学

      Volume: 86(6) Pages: 798-802

    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] Mucosal adjuvants for vaccines to control upper respiratory infections in the elderly.2014

    • Author(s)
      Fujihashi, K., Sato S., and Kiyono, H.
    • Journal Title

      Experimental Gerontology

      Volume: 54 Pages: 21-26

    • DOI
      10.1016/j.exger.2014.01.006
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-25860353
  • [Journal Article] New era for mucosal mast cells: their roles in inflammation, allergic immune responses and adjuvant development.2014

    • Author(s)
      Kurashima Y, Kiyono H.
    • Journal Title

      Exp. Mol. Med.

      Volume: 46

    • DOI
      10.1038/emm.2014.7
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-11J04859, KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-26893047
  • [Journal Article] Regulation of intestinal IgA responses by dietary palmitic acid and its metabolism2014

    • Author(s)
      Kunisawa J, Hashimoto E, Inoue A, Nagasawa R, Suzuki Y, Ishikawa I, Shikata S, Arita M, Aoki J, Kiyono H.
    • Journal Title

      J Immunol

      Volume: 193 Pages: 1666-1671

    • DOI
      10.4049/jimmunol.1302944
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116006, KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-24659217, KAKENHI-PUBLICLY-25116706, KAKENHI-PROJECT-26293111, KAKENHI-PROJECT-26670241
  • [Journal Article] The mucosal immune system for vaccine development.2014

    • Author(s)
      Lamichhane, A., Azegami, T. and Kiyono, H.
    • Journal Title

      Vaccine

      Volume: 32(49) Pages: 6711-6723

    • DOI
      10.1016/j.vaccine.2014.08.089
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] 次世代ワクチン開発への課題と挑戦-経口ワクチン-2014

    • Author(s)
      鹿島光司、幸義和、清野宏
    • Journal Title

      BIO INDUSTRY

      Volume: 31(6) Pages: 4-10

    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] Runx2-I Isoform Contributes to Fetal Bone Formation Even in the Absence of Specific N-Terminal Amino Acids.2014

    • Author(s)
      Nakajima-Adachi, H., Kikuchi, A., Fujimura, Y., Shibahara, K., Makino, T., Goseki-Sone, M., Kihara-Fujioka, M., Nochi, T., Kurashima, Y., Igarashi, O., Yamamoto, M., Kunisawa, J., Toda, M., Kaminogawa, S., Sato, R., Kiyono, H., and Hachimura, S.
    • Journal Title

      PLoS One

      Volume: 9 Pages: 108294-108294

    • DOI
      10.1371/journal.pone.0108294
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-24390412, KAKENHI-PROJECT-25670773, KAKENHI-PROJECT-25860353
  • [Journal Article] Peyer's patches play a protective role in nonsteroidal anti-inflammatory drug-induced enteropathy in mice2014

    • Author(s)
      Hiyama S, Iijima H, Shinzaki S, Inoue T, Shiraishi E, Kawai S, Araki M, Kato M, Hayashi Y, Nishida T, Fujii H, Mukai A, Shibata N, Sato S, Kiyono H, Gotoh K, Motooka D, Nakamura S, Iida T, Tsujii M, Takehara T.
    • Journal Title

      Inflammatory Bowel Diseases

      Volume: 5 Pages: 790-799

    • DOI
      10.1097/mib.0000000000000017
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-14J08881, KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-23590941, KAKENHI-PROJECT-24390188, KAKENHI-PROJECT-25860353, KAKENHI-PROJECT-26460969
  • [Journal Article] Innate lymphoid cells regulate intestinal epithelial cell glycosylation.2014

    • Author(s)
      Goto, Y., Obata, T., Kunisawa, J., Sato, S., Ivanov, I., Lamichhane, A., Takeyama, N., Kamioka, M., Sakamoto, M., Matsuki, T., Setoyama, H., Imaoka, A., Uematsu, S., Akira, S., Domino, S., Kulig, P., Becher, B., Renauld, J-C., Sasakawa, C., Umesaki, Y., Benno, Y. and Kiyono, H.
    • Journal Title

      Science

      Volume: 345(6202) Pages: 1254009-1254009

    • Acknowledgement Compliant / Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] Challenge in mucosal vaccines for the control of infectious diseases.2014

    • Author(s)
      Azegami, T., Yuki, Y., and Kiyono, H.
    • Journal Title

      Int. Immunol.

      Volume: 26 Pages: 517-528

    • DOI
      10.1093/intimm/dxu063
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] 粘膜ワクチンを基盤とした次世代ワクチンの開発2014

    • Author(s)
      福山賀子、清野宏
    • Journal Title

      最新医学

      Volume: 69(4) Pages: 62-69

    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] Specific Expression of Apolipoprotein A-IV in the Follicle-Associated Epithelium of the Small Intestine2014

    • Author(s)
      Tokuhara, D., Nochi, T., Matsumura, A., Mejima, M., Takahashi, Y., Kurokawa, S., Kiyono, H. and Yuki Y.
    • Journal Title

      Dig Dis Sci.

      Volume: 59 Pages: 2682-2692

    • DOI
      10.1007/s10620-014-3203-6
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-24659203, KAKENHI-PROJECT-26660245
  • [Journal Article] Generation of colonic IgA-secreting cells in the caecal patch.2014

    • Author(s)
      Masahata, K., Umemoto, E., Kayama, H., Kotani, M., Nakamura, S., Kurakawa, T., Kikuta, J., Gotoh, K., Motooka, D., Sato, S., Higuchi, T., Baba, Y., Kurosaki, T., Kinoshita, M., Shimada, Y., Kimura, T., Okumura, R., Takeda, A., Tajima, M., Yoshie, O., Fukuzawa, M., Kiyono, H., Fagarasan, S., Iida, T., Ishii, M., Takeda, K
    • Journal Title

      Nature Comm.

      Volume: 5 Pages: 1-13

    • DOI
      10.1038/ncomms4704
    • Peer Reviewed / Open Access / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-21229007, KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-23501273, KAKENHI-PROJECT-23591632, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-24390120, KAKENHI-PROJECT-24590252, KAKENHI-PROJECT-24689023, KAKENHI-PROJECT-25670272, KAKENHI-PROJECT-25860353, KAKENHI-PROJECT-25893117, KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-26460582, KAKENHI-PROJECT-26461437
  • [Journal Article] A rice-based soluble form of a murine TNF -specific llama variable domain of heavy-chain antibody suppresses collagen -induced arthritis in mice.2014

    • Author(s)
      Abe, M., Yuki, Y., Kurokawa, S., Mejima, M., Kuroda, M., Park, E.J., Scheller, J. Nakanishi, U. and Kiyono, H.
    • Journal Title

      J. Biotechnol.

      Volume: 10:175 Pages: 45-52

    • DOI
      10.1016/j.jbiotec.2014.02.005
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] 抑制型免疫システムを応用した次世代型抗アレルギーワクチンの開発2014

    • Author(s)
      高里良宏、倉島洋介、清野宏、國澤純
    • Journal Title

      BIO INDUSTRY

      Volume: 31(6) Pages: 55-60

    • Data Source
      KAKENHI-PROJECT-23229004
  • [Journal Article] Epithelial barrier: an interface for the cross-communication between gut flora and immune system.2012

    • Author(s)
      Goto, Y., Kiyono, H.
    • Journal Title

      Immunol Rev.

      Volume: 245 Pages: 147-163

    • DOI
      10.1111/j.1600-065x.2011.01078.x
    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-19059009, KAKENHI-PROJECT-23229004
  • [Journal Article] Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors2012

    • Author(s)
      Kurashima Y, Amiya T, Nochi T, Fujisawa K, Haraguchi T, Iba H, Tsutsui H, Sato S, Nakajima S, Iijima H, Kubo M, Kunisawa J, Kiyono H
    • Journal Title

      Nat Commun

      Volume: 3 Pages: 1034-1034

    • Data Source
      KAKENHI-PROJECT-23590941
  • [Journal Article] Distinct fucosylation of M cells and epithelial cells by Fut1 and Fut2, respectively, in response to intestinal environmental stress2011

    • Author(s)
      Terahara, K., Nochi, T., Yoshida, M., Takahashi, Y., Goto, Y., Hatai, H., Kurokawa, S., Jang, H-M., Kweon, M-N, Domino, SE., Hiroi, T., Yuki, Y., Tsunetsugu-Yokota, Y., Kobayashi, K., and Kiyono, H
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 404 Pages: 822-828

    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] The airway antigen sampling system: Respiratory M cells as an alternative gateway for inhaled antigens2011

    • Author(s)
      Kim, D-Y., Sato, A., Fukuyama, S., Sagara, H, Nagatake, T., Kong, IG., Goda, K., Nochi, T., Kunisawa, J., Sato, S., Yokota, Y., Lee, CH., and Kiyono, H
    • Journal Title

      J. Immunol

      Volume: 186 Pages: 4253-4262

    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Peaceful mutualism in the gut : revealing key commensal bacteria for the creation and maintenance of immunological homeostasis.2011

    • Author(s)
      Kunisawa J, Kiyono H.
    • Journal Title

      Cell Host Microbe.

      Volume: 17 Pages: 83-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Distinct fucosylation of M cells and epithelial cells by Fut1 and Fut2, respectively, in response to intestinal environmental stress.2011

    • Author(s)
      Terahara K, Nochi T, Yoshida M, Takahashi Y, Goto Y, Hatai H, Kurokawa S, Jang MH, Kweon MN, Domino SE, Hiroi T, Yuki Y, Tsunetsugu-Yokota Y, Kobayashi K, Kiyono H.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 404 Pages: 822-828

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] Epithelial cell microRNAs in gut immunity.2011

    • Author(s)
      Goto Y, Kiyono H.
    • Journal Title

      Nat Immunol.

      Volume: 12 Pages: 195-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Distinct fucosylation of M cells and epithelial cells by Fut1 and Fut2, respectively, in response to intestinal environmental stress.2011

    • Author(s)
      Terahara K, Nochi T, Yoshida M, Takahashi Y, Goto Y, Hatai H, Kurokawa S, Jang MH, Kweon MN, Domino SE, Hiroi T, Yuki Y, Tsunetsugu-Yokota Y, Kobayashi K, Kiyono H.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 404 Pages: 822-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Peaceful mutualism in the gut: revealing key commensal bacteria for the creation and maintenance of immunological homeostasis2011

    • Author(s)
      Kunisawa, J., and Kiyono, H
    • Journal Title

      Cell Host Microbe

      Volume: 9 Pages: 83-84

    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Epithelial cell microRNAs in gut immunity2011

    • Author(s)
      Goto, Y., and Kiyono, H
    • Journal Title

      Nat Immunol

      Volume: 12 Pages: 195-197

    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Mucosal regulatory cells in the gastrointestinal tract and periodontium.2010

    • Author(s)
      Takahashi I, Fujihashi K, Kiyono H.
    • Journal Title

      Periodontol

      Volume: 54 Pages: 247-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Secretory IgA-mediated protection against V.cholerae and heat-labileenterotoxin-producing enterotoxigenic Escherichia coli by rice-based vaccine.2010

    • Author(s)
      Tokuhara D, Yuki Y, Nochi T, Kodama T, Mejima M, Kurokawa S, Takahashi Y, Nanno M, Nakanishi U, Takaiwa F, Honda T, Kiyono H.
    • Journal Title

      Proc Natl Acad Sci USA.

      Volume: 107 Pages: 8794-8799

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] In vivo molecular imaging analysis of a nasal vaccine that induces protective immunity against botulism in nonhuman primates.2010

    • Author(s)
      Yuki Y, Nochi T, Harada N, Katakai Y, Shibata H, Mejima M, Kohda T, Tokuhara D, Kurokawa S, Takahashi Y, Ono F, Kozaki S, Terao K, Tsukada H, Kiyono H.
    • Journal Title

      J Immunol.

      Volume: 185 Pages: 5436-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines2010

    • Author(s)
      Nochi, T., Yuki, Y., Takahashi, H., Sawada, SI., Mejima, M., Kohda, T., Harada, N., Kong, IG., Sato, A., Kataoka, N., Tokuhara, D., Kurokawa, S., Takahashi, Y., Tsukada, H., Kozaki, S., Akiyoshi, K., and Kiyono, H
    • Journal Title

      Nature Mater

      Volume: 9 Pages: 572-578

    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] IL-15 triggers an antiapoptotic pathway in human intraepithelial lymphocytes that is a potential new target in celiac disease-associated inflammation and lymphomagenesis.2010

    • Author(s)
      Malamut G, El Machhour R, Montcuquet N, Martin-Lanneree S, Dusanter-Fourt I, Verkarre V, Mention JJ, Rahmi G, Kiyono H, Butz EA, Brousse N, Cellier C, Cerf-Bensussan N, Meresse B.
    • Journal Title

      J Clin Invest.

      Volume: 120 Pages: 2131-2143

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] Secretory IgA-mediated protection against V.cholerae and heat-labile enterotoxin-producing enterotoxigenic Escherichia coli by rice-based vaccine.2010

    • Author(s)
      Tokuhara D, Yuki Y, Nochi T, Kodama T, Mejima M, Kurokawa S, Takahashi Y, Nanno M, Nakanishi U, Takaiwa F, Honda T, Kiyono H.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 107 Pages: 8794-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Indigenous opportunistic bacteria inhabit mammalian gut-associated lymphoid tissues and share a mucosal antibody-mediated symbiosis2010

    • Author(s)
      Obata, T., Goto, Y., Kunisawa, J., Sato, S., Sakamoto, M., Setoyama, H., Matsuki, T., Nonaka, K., Shibata, N., Gohda, M., Kagiyama, Y., Nochi, T., Yuki, Y., Fukuyama, Y., Mukai, A., Shinzaki, S., Fujihashi, K., Sasakawa, C., Iijima, H., Goto, M., Umesaki, Y., Benno, Y., and Kiyono, H
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 107 Pages: 7419-7424

    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Aberrant interaction of the gut immune system with environmentalfactors in the development of food allergies.2010

    • Author(s)
      Kunisawa J, Kiyono H.
    • Journal Title

      Curr Allergy Asthma Rep.

      Volume: 10 Pages: 215-221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] Aberrant interaction of the gut immune system with environmental factors in the development of food allergies.2010

    • Author(s)
      Kunisawa J, Kiyono H.
    • Journal Title

      Curr Allergy Asthma Rep.

      Volume: 10 Pages: 215-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Antigen-sampling cells in the salmonid intestinal epithelium.2010

    • Author(s)
      Fuglem B, Jirillo E, Bjerkas I, Kiyono H, Nochi T, Yuki Y, Raida M, Fischer U, Koppang EO.
    • Journal Title

      Dev Comp Immunol.

      Volume: 34 Pages: 768-774

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] Aberrant interaction of the gut immune system with environmental factors in the development of food allergies.2010

    • Author(s)
      Kunisawa J, Kiyono H.
    • Journal Title

      Curr Allergy Asthma Rep. 10

      Pages: 215-221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus.2010

    • Author(s)
      Kayamuro H, Yoshioka Y, Abe Y, Arita S, Katayama K, Nomura T, Yoshikawa T, Kubota-Koketsu R, Ikuta K, Okamoto S, Mori Y, Kunisawa J, Kiyono H, Itoh N, Nagano K, Kamada H, Tsutsumi Y, Tsunoda S.
    • Journal Title

      J Vjrol.

      Volume: 84 Pages: 12703-12712

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] High affinity of interaction between superantigen and T cell receptor Vbeta molecules induces a high level and prolonged expansion of superantigen-reactive CD4+ T cells.2010

    • Author(s)
      Omoe K, Nunomura W, Kato H, Li ZJ, Igarashi O, Araake M, Sano K, Ono HK, Abe Y, Hu DL, Nakane A, Kiyono H, Takakuwa Y, Shinagawa K, Uchiyama T, Imanishi K.
    • Journal Title

      J Biol Chem.

      Volume: 285 Pages: 30427-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] IL-15 triggers an antiapoptotic pathway in human intraepithelial lymphocytes that is a potential new target in celiac disease-associated inflammation and lymphomagenesis.2010

    • Author(s)
      Malamut G, El Machhour R, Montcuquet N, Martin-Lanneree S, Dusanter-Fourt I, Verkarre V, Mention JJ, Rahmi G, Kiyono H, Butz EA, Brousse N, Cellier C, Cerf-Bensussan N, Meresse B.
    • Journal Title

      J Clin Invest.

      Volume: 120 Pages: 2131-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines.2010

    • Author(s)
      Nochi T, Yuki Y, Takahashi H, Sawada S, Mejima M, Kohda T, Harada N, Kong IG, Sato A, Kataoka N, Tokuhara D, Kurokawa S, Takahashi Y, Tsukada H, Kozaki S, Akiyoshi K, Kiyono H.
    • Journal Title

      Nat Mater.

      Volume: 9 Pages: 572-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Mucosal regulatory cells in the gastrointestinal tract and periodontium.2010

    • Author(s)
      Takahashi I, Fujihashi K, Kiyono H.
    • Journal Title

      Periodontol

      Volume: 54 Pages: 247-256

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] In vivo molecular imaging analysis of a nasal vaccine that induces protective immunity against botulism in nonhuman primates.2010

    • Author(s)
      Yuki Y, Nochi T, Harada N, Katakai Y, Shibata H, Mejima M, Kohda T, Tokuhara D, Kurokawa S, Takahashi Y, Ono F, Kozaki S, Terao K, Tsukada H, Kiyono H.
    • Journal Title

      JImmunol.

      Volume: 185 Pages: 5436-5443

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] Indigenous opportunistic bacteria inhabit mammalian gut-associated lymphoid tissues and share a mucosal antibody-mediated symbiosis.2010

    • Author(s)
      Obata T, Goto Y, Kunisawa J, Sato S, Sakamoto M, Setoyama H, Matsuki T, Nonaka K, Shibata N, Gohda M, Kagiyama Y, Nochi T, Yuki Y, Fukuyama Y, Mukai A, Shinzaki S, Fujihashi K, Sasakawa C, Iijima H, Goto M, Umesaki Y, Benno Y, Kiyono H.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 107 Pages: 7419-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines.2010

    • Author(s)
      Nochi T, Yuki Y, Takahashi H, Sawada S, Mejima M, Kohda T, Harada N, Kong IG, Sato A, Kataoka N, Tokuhara D, Kurokawa S, Takahashi Y, Tsukada H, Kozaki S, Akiyoshi K, Kiyono H.
    • Journal Title

      Nat Mater.

      Volume: 9 Pages: 572-578

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus.2010

    • Author(s)
      Kayamuro H, Yoshioka Y, Abe Y, Arita S, Katayama K, Nomura T, Yoshikawa T, Kubota-Koketsu R, Ikuta K, Okamoto S, Mori Y, Kunisawa J, Kiyono H, Itoh N, Nagano K, Kamada H, Tsutsumi Y, Tsunoda S.
    • Journal Title

      J Virol.

      Volume: 84 Pages: 12703-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Indigenous opportunistic bacteria inhabit mammalian gut-associatedlymphoid tissues and share a mucosal antibody-mediated symbiosis.2010

    • Author(s)
      Obata T, Goto Y, Kunisawa J, Sato S, Sakamoto M, Setoyama H, Matsuki T, Nonaka K, Shibata N, Gohda M, Kagiyama Y, Nochi T, Yuki Y, Fukuyama Y, Mukai A, Shinzaki S, Fujihashi K, Sasakawa C, Iijima H, Goto M, Umesaki Y, Benno Y, Kiyono H.
    • Journal Title

      Proc Natl Acad Sci USA.

      Volume: 107 Pages: 7419-7424

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] Secretory IgA-mediated protection against V. cholerae and heat-labile enterotoxin-producing enterotoxigenic Escherichia coli by rice-based vaccine2010

    • Author(s)
      Tokuhara, D., Yuki, Y., Nochi, T., Kodama, T., Mejima, M., Kurokawa, S., Takahashi, Y., Nanno, M., Nakanishi, U., Takaiwa, F., Honda, T., and Kiyono, H
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 107 Pages: 8794-8799

    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response2009

    • Author(s)
      Hase, K., Kawano, K., Nochi, T., Pontes, GS., Fukuda, S., Ebisawa, M., Kadokura, K., Tobe, T., Fujimura, Y., Kawano, S., Yabashi, A., Waguri, S., Nakato, G., Kimura, S., Murakami, T., Iimura, M., Hamura, K., Fukuoka, S., Lowe, AW., Itoh, K., Kiyono, H., and Ohno, H
    • Journal Title

      Nature

      Volume: 462 Pages: 226-230

    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Id2-, RORγt-, and LTβR-independent lymphoid organogenesis in ocular immunity2009

    • Author(s)
      Nagatake, T., Fukuyama, S, Kim. D-Y., Goda, K., Igarashi.O., Sato,S., Nochi, T., Sagara, H.,Yokota, Y., Jetten, AM., Kaisho, T., Akira, A., Mimuro, H., Sasakawa, C., Fukui, Y., Fujihashi, K., Akiyama, T., Inoue, J., Penninger, J.M., Kunisawa, J., and Kiyono, H
    • Journal Title

      J. Exp. Med

      Volume: 206 Pages: 2351-2364

    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] RANKL is necessary and sufficient to initiate development of antigen-sampling M cells in the intestinal epithelium2009

    • Author(s)
      Knoop, KA., Kumar, N., Butler, BR., Sakthivel, SK., Taylor, RT., Nochi, T., Akiba, H., Yagita, H., Kiyono, H., and Williams, IR
    • Journal Title

      J. Immunol

      Volume: 183 Pages: 5738-5747

    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Mucosal immunosenescence : New developments and vaccines to contr-olinfectious diseases2009

    • Author(s)
      Fujihashi, K., Kiyono, H.
    • Journal Title

      Trends Immunol 30

      Pages: 334-343

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Mucosal vaccines : novel advances in technology and delivery2009

    • Author(s)
      Yuki, Y., Kiyono, H.
    • Journal Title

      Expert Rev Vaccines 8

      Pages: 1083-1097

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Expression of newly identified secretory CEACAM1(a) isoforms in the intestional epithelium2009

    • Author(s)
      Terahara, K., Yoshida, M., Taguchi, F., Igarashi, O., Nochi, T., Gotoh, Y., Yamamoto, T., Tsunetsugu-Yokota, Y., Beauchemin, N., and Kiyono, H
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 383 Pages: 340-346

    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] A Rice-based oral cholera vaccine induces macaque-specific systemic neutralizing Abs but does not influence pre-existing intestinal immunity2009

    • Author(s)
      Nochi, T., Yuki,Y., Katakai, Y., Shibata, H., Tokuhara,D., Mejima, M., Kurokawa,S., Takahashi,Y., Nakanishi, U., Ono, F., Mimuro, H., Sasakawa, S., Takaiwa, F., Terao, K., and Kiyono, H
    • Journal Title

      J. Immunol

      Volume: 183 Pages: 6538-6544

    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Mucosal immunosenescence : New developments and vaccines to contr-ol infectious diseases.2009

    • Author(s)
      Fujihashi, K., Kiyono, H.
    • Journal Title

      Trends Immunol. 30

      Pages: 334-343

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] Mucosal immunosenescence : New developments and vaccines to control infectious diseases2009

    • Author(s)
      Fujihashi, K. and Kiyono, H
    • Journal Title

      Trends Immunol

      Volume: 30 Pages: 334-343

    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Mucosal vaccines : novel advances in technology and delivery.2009

    • Author(s)
      Yuki, Y., Kiyono, H.
    • Journal Title

      Expert Rev Vaccines. 8

      Pages: 1083-1097

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] Peyer's patches are required for intestinal IgA responses to Salmonella.2008

    • Author(s)
      Hashizume, T., Togawa, A., Nochi, T., Igarashi, O., Kweon, M. N. , Kiyono, H. and Yamamoto, M.
    • Journal Title

      Infect Immun. 76

      Pages: 927-934

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] Comprehensive gene expression analysis among peyer's patch M cells, villous M cells and intestinal epithelial cells by DNA microarray analysis.2008

    • Author(s)
      Terahara, T., Igarashi, O., Yoshida, M., Nochi, T., Kurokawa, S., Takayama, N., Yuki, Y., Low, AW. and Kiyono, H.
    • Journal Title

      J. Immunol. 180

      Pages: 7840-7846

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Immunological commonalities and distinctions between airway and digestive immunity.2008

    • Author(s)
      Kunisawa, J., Nochi, T. and Kiyono, H.
    • Journal Title

      Trends Immunol. 29

      Pages: 505-513

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Sphingosine 1-phosphate-dependent trafficking of peritoneal B cells requires functional NFκB-inducing kinase in stromal cells.2008

    • Author(s)
      Kunisawa, J., Gohda, M., Kurashima, Y., Ishikawa, I., Higuchi, M. and Kiyono, H.
    • Journal Title

      Blood. 111

      Pages: 4646-4652

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Colonic patches direct the cross-talk between systemic compartments and large intestine independently of innate immunity2008

    • Author(s)
      Chang, SY., Cha, HR., Uematsu, S., Akira, S., Igarashi, O., Kiyono, H., and Kweon, M-N
    • Journal Title

      J. Immunol

      Volume: 180 Pages: 1609-18

    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Immunological commonalities and distinctions between airway and digestive immunity.2008

    • Author(s)
      Kunisawa, J., Nochi, T. and Kiyono, H.
    • Journal Title

      Trends Immunol. 29

      Pages: 505-513

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] Sphingosine 1-phosphate regulates the egress of IgA plasmablasts from Peyer's patches for intestinal IgA responses.2008

    • Author(s)
      Gohda, M., Kunisawa, J., Miura, F., Kagiyama, Y., Kurashima, Y., Higuchi, M., Ishika wa, I., Ogahara, I. and Kiyono, H.
    • Journal Title

      J. Immunol. 180

      Pages: 5335-5343

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Sphingosine 1-phosphate-dependent trafficking of peritoneal B cells requires functional NFkB-inducing kinase in stromal cells.2008

    • Author(s)
      Kunisawa, J., Gohda, M., Kurashima, Y., Ishikawa, I., Higuchi, M . and Kiyono, H.
    • Journal Title

      Blood. 111

      Pages: 4646-4652

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] Nasal Vaccination with the 40-Kilodalton outer membrane protein of Porphyromonas gingivalis and a nontoxic chimeric enterotoxin adjuvant induces lomg-term protective immunity with reduced levels of immunoglobulin E antibodies.2008

    • Author(s)
      Momoi, F., Hashizume, T., Kurita-Ochiai, T., Yuki, Y., Kiyono, H ., and Yamamoto, M.
    • Journal Title

      Infect Immun. 76

      Pages: 7840-7846

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] The mucosa : at the frontlines of immunity.2008

    • Author(s)
      Fehervaril, Z., and Kiyono, H.
    • Journal Title

      Trends Immunol 29

      Pages: 503-504

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Nasal Vaccination with the 40-Kilodalton outer membrane protein of Porphyromonas gingivalis and a nontoxic chimeric enterotoxin adjuvant induces lomg-term protective immunity with reduced levels of immunoglobulin E antibodies.2008

    • Author(s)
      Momoi, F., Hashizume, T., Kurita-Ochiai, T., Yuki, Y., Kiyono, H., and Yamamoto, M.
    • Journal Title

      Infect Immun. 76

      Pages: 7840-7846

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Tonic B cell activation by radioprotective105/MD-1 promotes diseaseprogression in MRL/lpr mice.2008

    • Author(s)
      Kobayashi T, Takahashi K, Nagai Y, Shibata T, Otani M, Izui S, Akira S, Gotoh Y, Kiyono H, and Miyake K.
    • Journal Title

      Int Immunol. 20

      Pages: 881-891

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Comprehensive gene expression analysis among Peyer's patch M cells, villous M cells and intestinal epithelial cells by DNA microarray analysis2008

    • Author(s)
      Terahara, K., Yoshida, M., Igarashi, O., Nochi, T., Pontes, GS., Hase, K., Ohno, H., Kurokawa, S., Mejima, M., Takayama, N., Yuki, Y., Lowe, AW. and Kiyono, H
    • Journal Title

      J. Immunol

      Volume: 180 Pages: 7840-7846

    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] The mucosa: at the frontlines of immunity2008

    • Author(s)
      Fehervari1, Z., and Kiyono, H
    • Journal Title

      Trends Immunol

      Volume: 29 Pages: 503-504

    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Peyer's patches are required for intestinal IgA responses to Salmonella.2008

    • Author(s)
      Hashizume, T., Togawa, A., Nochi, T., Igarashi, O., Kweon, M.N., Kiyono, H. and Yamamoto, M.
    • Journal Title

      Infect Immun. 76

      Pages: 927-934

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 52008

    • Author(s)
      Uematsu, S., Fujimoto, K., Jang, MH., Yang, BG., Jung, YJ., Nishiyama, M., Sato, S., Tsujimura, T., Yamamoto, M., Yokota, Y., Kiyono, H., Miyasaka, M., Ishii, KJ., and Akira, S
    • Journal Title

      Nature Immunol

      Volume: 9 Pages: 769-776

    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Cutting edge : Langerin+ dendritic cells in the mesenteric lymph node set the stage for skin and gut immune system cross-talk.2008

    • Author(s)
      Chang, SY., Cha, HR., Igarashi, O., Rennert, PD., Kissenpfennig, A., Malissen, B., Nanno, M., Kiyono, H., and Kweon, MN.
    • Journal Title

      J. Immunol. 180

      Pages: 4361-4365

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Comprehensive gene expression analysis among peyer's patch M cells, villous M cells and intestinal epithelial cells by DNA microarray analysis.2008

    • Author(s)
      Terahara, T., Igarashi, O., Yoshid a, M., Nochi, T., Kurokawa, S.,Takayama, N., Yuki, Y., Low, A W. and Kiyono, H.
    • Journal Title

      J. Immunol. 180

      Pages: 7840-7846

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] Peyer's patches are required for intestinal IgA responses to Salmonella2008

    • Author(s)
      Hashizume, T., Togawa, A., Nochi, T., Igarashi, O., Kweon, MN., Kiyono, H. and Yamamoto, M
    • Journal Title

      Infect. Immun

      Volume: 76 Pages: 927-934

    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Sphingosine 1-phosphate regulates the egress of IgA plasmablasts from Peyer's patches for intestinal IgA responses.2008

    • Author(s)
      Gohda, M., Kunisawa, J., Miura, F., Kagiyama, Y., Kurashima, Y. , Higuchi, M., Ishikawa, I., Ogahara, I. and Kiyono, H.
    • Journal Title

      J. Immunol. 180

      Pages: 5335-5343

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] Colonic patches direct the cross-talk between systemic compartments and large intestine independently of innate immunity.2008

    • Author(s)
      Sun-Young Chang, Hye-Ran Cha, Uematsu, S., Akira, S., Igarashi, 0., Kiyono, H., and Mi-Na Kweon
    • Journal Title

      J. Immunol. 180

      Pages: 1609-1618

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5.2008

    • Author(s)
      Uematsu, S., Fujimoto, K., Jang, MH., Yang, BG., Jung, YJ., Nishiyama, M., Sato, S., Tsujimura, T., Yamamoto, M., Yokota, Y., Kiyono, H., Miyasaka, M., Ishii, KJ., Akira, S.
    • Journal Title

      Nat Immunol 9

      Pages: 769-776

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Journal Article] Colonic patches direct the cross-talk between systemic compartments and large intestine independently of innate immunity.2008

    • Author(s)
      Sun-Young Chang, Hye-Ran Cha, Uematsu, S., Akira, S., Igaras hi, O., Kiyono, H.,and Mi-Na Kweon
    • Journal Title

      J. Immunol 180

      Pages: 1609-1618

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Journal Article] Therapeutic effects of roxithromycin in Interleukin-10-deficient colitis.2007

    • Author(s)
      H.Tamagawa, T.Hiroi, T.Mizushima, T.Ito, H.Matsuda, H.Kiyono
    • Journal Title

      Inflamm Bowel Dis (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591311
  • [Journal Article] Therapeutic effects of roxithromycin in Interleukin-10-deficient colitis2007

    • Author(s)
      H.Tamagawa, T.Hiroi, T.Mizushima, T.Ito, H.Matsuda, H.Kiyono
    • Journal Title

      Inflamm Bowel Dis (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591311
  • [Journal Article] Colitis in mice lacking the common cytokine receptor gamma chain is mediated by IL-6-producing CD4+T cells.2005

    • Author(s)
      Kai, Y., Takahashi, I., Ishikawa, H., Hiroi, T., Mizushima, T., Matsuda, C., Kishi, D., Hamada, H., Tamagawa, H., Ito, T., Yoshizaki, K., Kishimoto, T., Matsuda, H., Kiyono, H.
    • Journal Title

      Gastroenterology. 128

      Pages: 922-934

    • Data Source
      KAKENHI-PROJECT-16017230
  • [Journal Article] A rice-based edible vaccine expressing multiple T cell epitopes induces oral tolerance for inhibition of Th-2 mediated IgE responses.2005

    • Author(s)
      Takagi, H., Hiroi, H., Yang, L., Tada, Y., Yuki, Y., Takamura, K., Ishimitsu, R., Kawauchi, H., Kiyono, H., Takaiwa, F.
    • Journal Title

      Proc.Nat.Acad.Sci.USA. 102

      Pages: 17525-17530

    • Data Source
      KAKENHI-PROJECT-16017230
  • [Journal Article] Prenatal blockage of lymphotoxin beta receptor and TNF receptor p55 signaling cascade resulted in the acceleration of tissue genesis for isolated lymphoid follicles in the large intestine.2005

    • Author(s)
      Kweon, M.N., Yamamoto, M., Rennert, P.D., Park, E.J., Lee, A.Y., Chang, S.Y., Hiroi, T., Nanno, M., Kiyono, H
    • Journal Title

      J.Immunol. 174

      Pages: 4365-4372

    • Data Source
      KAKENHI-PROJECT-16017230
  • [Journal Article] Production of a recombinant cholera toxin B subunit-insulin B chain peptide hybrid protein by Brevibacillus choshinensis expression system as a nasal vaccine against autoimmune diabetes.2005

    • Author(s)
      Yuki, Y., Hara-Yakoyama, C., Guadiz, AA., Udak, S., Kiyono, H.
    • Journal Title

      Biotechnol.Bioeng. 92

      Pages: 803-809

    • Data Source
      KAKENHI-PROJECT-17047009
  • [Journal Article] A marvel of mucosal T cells and secretory antibodies for the creation of first lines of defense.2005

    • Author(s)
      Kunisawa, J., Kiyono, H.
    • Journal Title

      Cell Mol.Life Sci 62

      Pages: 1308-1321

    • Data Source
      KAKENHI-PROJECT-16017230
  • [Journal Article] Intestinal gamma delta T cells develop in mice lacking thymus, all lymph nodes, Peyer's patches, and isolated lymphoid follicles.2005

    • Author(s)
      Nonaka, S., Naito, T., Chen, H., Yamamoto, M., Moro, K., Kiyono, H.
    • Journal Title

      J.Immunol. 174

      Pages: 1906-1912

    • Data Source
      KAKENHI-PROJECT-16017230
  • [Journal Article] Prenatal blockage of lymphotoxin beta receptor and TNF receptor p55 signaling cascade resulted in the acceleration of tissue genesis for isolated lymphoid follicles in the large intestine.2005

    • Author(s)
      Kweon, M.N., Yamamoto, M., Rennert, P.D., Park, E.J., Lee, A.Y., Chang, S.Y., Hiroi, T., Nanno, M., Kiyono, H
    • Journal Title

      J.Immunol. 174

      Pages: 4365-4372

    • Data Source
      KAKENHI-PROJECT-17047009
  • [Journal Article] Mucosa-associated lymphoid tissues in the aerodigestive tract : their shared and divergent traits and their importance to the orchestration of the mucosal immune system.2005

    • Author(s)
      Kunisaw, J., Fukuyama, S., Kiyono, H.
    • Journal Title

      Curr.Mol.Med. 5

      Pages: 557-572

    • Data Source
      KAKENHI-PROJECT-16017230
  • [Journal Article] A marvel of mucosal T cells and secretory antibodies for the creation of first lines of defense.2005

    • Author(s)
      Kunisawa, J., Kiyono, H.
    • Journal Title

      Cell Mol.Life Sci 62

      Pages: 1308-1321

    • Data Source
      KAKENHI-PROJECT-17047009
  • [Journal Article] Nontoxic Shiga toxin derivatives from Escherichia coli possess adjuvant activity for the augmentation of antigen-specific immune responses via dendritic cell activation.2005

    • Author(s)
      Ohmura, M., Yamamoto, M., Tomiyama-Miyaji, C., Yuki, Y., Takeda, Y., Kiyono, H.
    • Journal Title

      Infect.Immun. 73

      Pages: 4088-4097

    • Data Source
      KAKENHI-PROJECT-16017230
  • [Journal Article] Colitis in mice lacking the common cytokine receptor gamma chain is mediated by IL-6-producing CD4+ T cells.2005

    • Author(s)
      Kai, Y., Takahashi, I., Ishikawa, H., Hiroi, T., Mizushima, T., Matsuda, C., Kishi, D., Hamada, H., Tamagawa, H., Ito, T., Yoshizaki, K., Kishimoto, T., Matsuda, H., Kiyono, H.
    • Journal Title

      Gastroenterology. 128

      Pages: 922-934

    • Data Source
      KAKENHI-PROJECT-17047009
  • [Journal Article] A novel neurotoxoid vaccine prevents mucosal botulism.2005

    • Author(s)
      Kobayashi, R., Kohda, T., Kataoka, K., Ihara, H., Kozaki, S., Pascual, DW., Staats, HF., Kiyono, H., McGhee, JR., Fujihashi, K.
    • Journal Title

      J.Immunol. 174

      Pages: 2190-2195

    • Data Source
      KAKENHI-PROJECT-16017230
  • [Journal Article] Intestinal gamma delta T cells develop in mice lacking thymus, all lymph nodes, Peyer's patches, and isolated lymphoid follicles.2005

    • Author(s)
      Nonaka, S., Naito, T., Chen, H., Yamamoto, M., Moro, K., Kiyono, H.
    • Journal Title

      J.Immunol. 174

      Pages: 1906-1912

    • Data Source
      KAKENHI-PROJECT-17047009
  • [Journal Article] Production of a recombinant cholera toxin B subunit-insulin B chain peptide hybrid protein by Brevibacillus choshinensis expression system as a nasal vaccine against autoimmune diabetes.2005

    • Author(s)
      Yuki, Y., Hara-Yakoyama, C., Guadiz, AA., Udak, S., Kiyono, H.
    • Journal Title

      Biotechnol.Bioeng. 92

      Pages: 803-809

    • Data Source
      KAKENHI-PROJECT-16017230
  • [Journal Article] Nontoxic Shiga toxin derivatives from Escherichia coli possess adjuvant activity for the augmentation of antigen-specific immune responses via dendritic cell activation.2005

    • Author(s)
      Ohmura, M., Yamamoto, M., Tomiyama -Miyaji, C., Yuki, Y., Takeda, Y., Kiyono, H.
    • Journal Title

      Infect.Immun. 73

      Pages: 4088-4097

    • Data Source
      KAKENHI-PROJECT-17047009
  • [Journal Article] A novel neurotoxoid vaccine prevents mucosal botulism.2005

    • Author(s)
      Kobayashi, R., Kohda, T., Kataoka, K., Ihara, H., Kozaki, S., Pascual, DW., Staats, HF., Kiyono, H., McGhee, JR., Fujihashi K.
    • Journal Title

      J.Immunol. 174

      Pages: 2190-2195

    • Data Source
      KAKENHI-PROJECT-17047009
  • [Journal Article] Mucosa-associated lymphoid tissues in the aerodigestive tract : their shared and divergent traits and their importance to the orchestration of the mucosal immune system.2005

    • Author(s)
      Kunisaw, J., Fukuyama, S., Kiyono, H.
    • Journal Title

      Curr.Mol.Med. 5

      Pages: 557-572

    • Data Source
      KAKENHI-PROJECT-17047009
  • [Journal Article] Triggering of TLR3 by polyI:C in human corneal epithelial cells to induce inflammatory cytokines.2005

    • Author(s)
      Ueta, M., Hamuro, J., Kiyono, H., Kinoshita, S.
    • Journal Title

      Biochem.Biophys.Res.Commun. 331

      Pages: 285-294

    • Data Source
      KAKENHI-PROJECT-16017230
  • [Journal Article] A rice-based edible vaccine expressing multiple T cell epitopes induces oral tolerance for inhibition of Th-2 mediated IgE responses.2005

    • Author(s)
      Takagi, H., Hiroi, H., Yang, L., Tada, Y., Yuki, Y., Takamura, K., Ishimitsu, R., Kawauchi, H., Kiyono, H., Takaiwa, F.
    • Journal Title

      Proc.Nat.Acad.Sci.USA. 102

      Pages: 17525-17530

    • Data Source
      KAKENHI-PROJECT-17047009
  • [Journal Article] Triggering of TLR3 by polyI:C in human corneal epithelial cells to induce inflammatory cytokines.2005

    • Author(s)
      Ueta, M., Hamuro, J., Kiyono, H., Kinoshita, S.
    • Journal Title

      Biochem.Biophys.Res.Commun. 331

      Pages: 285-294

    • Data Source
      KAKENHI-PROJECT-17047009
  • [Journal Article] Nalt-versus peyer' s patch-mediated mucosal imunity.2004

    • Author(s)
      Kiyono, H., Fukuyama S.
    • Journal Title

      Nature Reviews Immunology 4

      Pages: 699-710

    • Data Source
      KAKENHI-PROJECT-16017230
  • [Journal Article] Nalt-versus peyer' s-patch-mediated mucosal immunity2004

    • Author(s)
      Kiyono, H., Fukuyama, S.
    • Journal Title

      Nature Reviews Immunology 4

      Pages: 699-710

    • Data Source
      KAKENHI-PROJECT-16043214
  • [Journal Article] Peyer's patches play a protective role in non-steroidal anti-inflammatory drug-induced enteropathy in mice

    • Author(s)
      Hiyama S, Iijima H, Shinzaki S, Inoue T, Shiraishi E, Kawai S, Araki M, Kato M, Hayashi Y, Nishida T, Fujii H, Mukai A, Shibata N, Sato S, Kiyono H, Gotoh K, Motooka D, Nakamura S, Iida T, Tsujii M, Takehara T
    • Journal Title

      Inflamm Bowel Dis

      Volume: (In press)

    • Data Source
      KAKENHI-PROJECT-23590941
  • [Presentation] コメ型経口ワクチンMucoRice開発プロジェクト2017

    • Author(s)
      Kiyono H.
    • Organizer
      Joint Symposium of The University of Tokyo and Institute of Industrial Science, Activities lead by NY Office,
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2017-01-20
    • Int'l Joint Research / Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] 腸管マルチエコシステムによる炎症制御2017

    • Author(s)
      Kiyono, H.
    • Organizer
      The 17th Symposium on Japanese Society for Pediatoric Inflammatory Bowel Disease
    • Place of Presentation
      Osaka, Japan
    • Year and Date
      2017-02-05
    • Int'l Joint Research / Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] ガーナにおける感染症サーベイランス体制強化とコレラ菌・HIVなどの腸管粘膜感染防御に関する研究2016

    • Author(s)
      Kiyono H.
    • Organizer
      Japan Agency for Medical Research and Development’s 革新的医療技術創出拠点project Symposium
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2016-12-19
    • Int'l Joint Research / Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] MucoRice and NanoGel: New Generation of Mucosal Vaccines for Aero-digestive Infectious Diseases2016

    • Author(s)
      Kiyono H.
    • Organizer
      HWASUN International Vaccine Forum
    • Place of Presentation
      Hwasun, Korea
    • Year and Date
      2016-06-10
    • Int'l Joint Research / Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Epithlial Cells-Innate Lymphoid Cells-T Cells Trio-regulation for Gut homeostasis and Inflammation2016

    • Author(s)
      Kiyono H.
    • Organizer
      International Cytokine & Interferon Society, ICIS Cytokines 2016
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2016-10-18
    • Int'l Joint Research / Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Epithelial Cells-Innate Lymphoid Cells-Th Cells Trio-regulation for Gut Homeostasis and Inflammation2016

    • Author(s)
      Kiyono H.
    • Organizer
      The 4th Annual Meeting of the International Cytokine and Interferon Society
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2016-10-18
    • Int'l Joint Research / Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Regulation of Epithelial Clycosylation by Mucosal Immunity and Gut Microbiota2016

    • Author(s)
      Kiyono H.
    • Organizer
      The 23rd General meeting of the Japanese Association for Dental Science
    • Place of Presentation
      Fukuoka, Japan
    • Year and Date
      2016-10-23
    • Int'l Joint Research / Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Intenstinal M cells contribute to maintenance of gut immune homeostasis2016

    • Author(s)
      Kiyono H.
    • Organizer
      The 45th Annual Meeting of The Japanese Society for Immunology
    • Place of Presentation
      Okinawa, Japan
    • Year and Date
      2016-12-05
    • Int'l Joint Research / Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] カチオン化ナノゲルデリバリーシステムを用いた次世代型経鼻ワクチンの開発2016

    • Author(s)
      Kiyono H.
    • Organizer
      The 20th Annual meeting of the Japanese Society for Vaccinology
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2016-10-22
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] 粘膜免疫の最新情報と炎症性疾患の制御に向けた経粘膜治療戦略2016

    • Author(s)
      Kiyono H.
    • Organizer
      The 29th Annual Meeting of Japan Society of Stomata-pharyngology
    • Place of Presentation
      Matsue-shi, Shimane-ken
    • Year and Date
      2016-09-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Mucosal Multi-ecosystem for the Induction and Regulation of Symbiosis and Protection2016

    • Author(s)
      Kiyono H.
    • Organizer
      The 60th Annual General Assembly and Scientific Meeting of the Japan Colleage of Rheumatology.
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2016-04-23
    • Int'l Joint Research / Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Cutting Edge of Mucosal Immunology and Its Clinical Application2016

    • Author(s)
      Kiyono H.
    • Organizer
      International Symposium on Recent Advances in Rhinosinusitis and Nasal Polyposis
    • Place of Presentation
      Kuara Lumpur, Malaysia
    • Year and Date
      2016-11-21
    • Int'l Joint Research / Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Innate lymphoid cell and T cell synchronously regulate gut epithelial cell fucosylation2016

    • Author(s)
      Kiyono H.
    • Organizer
      The 10th International Symposium on Glycosyltransferases
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2016-06-19
    • Int'l Joint Research / Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Uniqueness of Mucosa-associated Lymphoid Tissues for Clinical Application2016

    • Author(s)
      Kiyono H.
    • Organizer
      The 40th Annual Meeting of the Japanese Society of Lymphology
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2016-06-25
    • Int'l Joint Research / Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] “The Mucosal Immune System for Symbiosis and Elimination”2015

    • Author(s)
      Kiyono, H.
    • Organizer
      The 34th Shirokane Symposium, The 50th Anniversary of Founding of the Kitasato University School of pharmacy
    • Place of Presentation
      Tokyo, Japan.
    • Year and Date
      2015-02-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] “Advancing the Knowledge of Immunology for Disease Treatments.”2015

    • Author(s)
      Kiyono, H.
    • Organizer
      Science Council of Japan and The Pharmaceutical Society of Japan Symposium
    • Place of Presentation
      Tokyo, Japan.
    • Year and Date
      2015-01-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] “Mucosal Immunity: The Adaptation of oral-Digestive Immune System for Vaccine Development”2015

    • Author(s)
      Kiyono, H.
    • Organizer
      The 3rd Medical Advisor Workshop, The Academy of Clinical Dentistry
    • Place of Presentation
      Tokyo, Japan.
    • Year and Date
      2015-02-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] “Mucosal Innate Lymphoid Cells and Mast Cells for the Regulation of Symbiosis and Inflammation”2015

    • Author(s)
      Kiyono, H.
    • Organizer
      World Immune Regulation Meeting IX
    • Place of Presentation
      Davos, Switzerland.
    • Year and Date
      2015-03-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] “Innovative Oral Vaccine:MucoRice”2015

    • Author(s)
      Kiyono, H.
    • Organizer
      “2015 Seminar for the Quality and Safety Improvements of Dental Practice” Kanagawa Dental Association
    • Place of Presentation
      Kanagawa, Japan.
    • Year and Date
      2015-03-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] “Mucosal Innate Immune System and Vaccine Development”2014

    • Author(s)
      Kiyono, H.
    • Organizer
      The 1st International Symposium on Mucosal Immunity and Vaccine Development 2014.
    • Place of Presentation
      Tokyo, Japan.
    • Year and Date
      2014-10-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] “Cross-talk between the Mucosal Immune System and Environmental Factors”2014

    • Author(s)
      Kiyono, H.
    • Organizer
      11th Nestl&eacute; International Nutrition Symposium on “Nutrition and the Human Gut Microbiome”
    • Place of Presentation
      Lausanne, Switzerland.
    • Year and Date
      2014-10-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] "Mucosal Connections Between Airway and Reproductive Immunity"2014

    • Author(s)
      Kiyono, H.
    • Organizer
      10th Research Symposium on Human Natural Defense System in Conjunction with PRAMS 2014 in Commemoration of the 10th Anniversary of The Airway Mucus Institute
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2014-10-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] “Oral Vaccine, MucoRice Fighting against the Diarrhea”2014

    • Author(s)
      Kiyono, H.
    • Organizer
      JSI organized Public Lecture Series Meneki Fushigi Mirai 2014.
    • Place of Presentation
      Tokyo, Japan.
    • Year and Date
      2014-08-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] “Mucosal Links between Innate-epithelial Cells and Commensal Flora for the Development of New Immune-prevention and -therapy”2014

    • Author(s)
      Kiyono, H.
    • Organizer
      2nd Novo Nordisk Innovation Summit 2014
    • Place of Presentation
      Tokyo, Japan.
    • Year and Date
      2014-10-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] “Microbial Molding of Mucosal Immunity”2014

    • Author(s)
      Kiyono, H.
    • Organizer
      ACR/ARHP Annual Meeting
    • Place of Presentation
      Boston, USA.
    • Year and Date
      2014-11-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] “Rice Protein Body and Cationic Nanogel as Antigen Delivery Vehicle for Mucosal Vaccines”2014

    • Author(s)
      Kiyono, H.
    • Organizer
      8th International Symposium on Nanomedicine (ISNM2014)
    • Place of Presentation
      Matsuyama, Ehime.
    • Year and Date
      2014-12-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] ”Fusion of Medical, Plant and Engineering Science Led to the Creation of Rice-based Vaccine, MucoRice”2014

    • Author(s)
      Kiyono, H.
    • Organizer
      SKIL Future Forum -Science Leads to Safe Life-
    • Place of Presentation
      Tokyo, Japan.
    • Year and Date
      2014-04-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] “Innate Lymphoid Cells Regulate Intestinal Epithelial Cell Fucosylation for Symbiosis and Elimination”2014

    • Author(s)
      Kiyono, H.
    • Organizer
      The 26th Symposium on Microbial Sciences ~The Symphony of Microbial Science and Medical care~
    • Place of Presentation
      Tokyo, Japan.
    • Year and Date
      2014-09-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] “Trends in Immunological Memory and Vaccine Development”, Organizer and Speaker, “Mucosal Immunity and Vaccine Development”2014

    • Author(s)
      Kiyono, H.
    • Organizer
      The 2nd Symposium of International Immunological Memory and Vaccine Forum, (IIMVF)
    • Place of Presentation
      La Jolla, USA.
    • Year and Date
      2014-08-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] “Development of Next Generation Vaccine based on Mucosal Immunology~Future of Mucosal Vaccine”2014

    • Author(s)
      Kiyono, H.
    • Organizer
      The 65th Kanto Region Otorhinolaryngology Allergy Discussion Group
    • Place of Presentation
      Tokyo, Japan.
    • Year and Date
      2014-09-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] “Development of Mucosal Immunology Driven Rice-based Vaccine “MucoRice” by the Fusion Research of Medical, Agricultural and Engineering Sciences”2014

    • Author(s)
      Kiyono, H.
    • Organizer
      The 13th Shikoku Immunology Forum 2014
    • Place of Presentation
      Tokushima, Japan.
    • Year and Date
      2014-06-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] “Can We Prevent Infectious Diseases by Rice?”2014

    • Author(s)
      Kiyono, H.
    • Organizer
      Seminar for Knowledge of Hub, National University Joint Usage-Research Center
    • Place of Presentation
      Tokyo, Japan.
    • Year and Date
      2014-04-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] “Rice-based Oral Vaccine “MucoRice” for the Control of Enteric Diarrheal Disease”2014

    • Author(s)
      Kiyono, H.
    • Organizer
      The 62nd Annual Meeting of the Japanese Society for Virology
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2014-11-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] “Mucosal Connections between Microbial Ecology and Immunity for the Homeostasis and Inflammatory Responses”2014

    • Author(s)
      Kiyono, H.
    • Organizer
      7th International Immunonutrition Workshop -Eating for Preventing-
    • Place of Presentation
      Carovigno, Italy.
    • Year and Date
      2014-05-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] The Mucosal immune system for New Generation of Prophylaxis and Therapeutic Nasal and Oral vaccines2013

    • Author(s)
      Kiyono, H.
    • Organizer
      The 7th International Symposium on Recent Advances in Rhinosinusitis and Nasal Polyposis
    • Place of Presentation
      Shimane, Japan.
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Reverse Control of ATP-P2X7-dependent Mast Cells in Mucosa and Skin for Inflammation2013

    • Author(s)
      Kiyono, H.
    • Organizer
      Annual Meeting of the French Society for Immunology
    • Place of Presentation
      Paris, France.
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Peyer's patches play a protective role in NSAIDs-induced small bowel injury2013

    • Author(s)
      Hiyama, S., Iijima, H., Shinzaki, S., Shibata, N., Sato S., Tsujii, M., Kiyono, H., Takehara, T
    • Organizer
      第42回日本免疫学会
    • Place of Presentation
      幕張メッセ
    • Data Source
      KAKENHI-PROJECT-23590941
  • [Presentation] The Intestinal Microbiota for Mucosal Decision of Immunity and Tolerance2013

    • Author(s)
      Kiyono, H.
    • Organizer
      International Yakult Symposium 2013 on “The Intestinal Microbiota and Probiotics: Exploiting Their Influence on Health”
    • Place of Presentation
      London, UK.
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] The Intestinal Immune System for Mucosal Connections of Immunity, Commensal Microbiota and Vaccine2013

    • Author(s)
      Kiyono, H.
    • Organizer
      2013 Joint Meeting of the 13th Aaian Pan-pacific Society for Pediatric Gastroenterology, Hepatology and Nuritutionand the 40th Japanese Society for Pediatric Gastroenterology, Hepatology and Nutrition
    • Place of Presentation
      Tokyo, Japan.
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Immunological Interventions and Vaccine Development for the Elderly2013

    • Author(s)
      Kiyono, H.
    • Organizer
      ICI 15th Satellite Symposium “Aging and the Immune System”
    • Place of Presentation
      Milan, Italy.
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] MucoRice System for New Generation of Prophylaxis and Therapeutic Oral Vaccine2013

    • Author(s)
      Kiyono, H.
    • Organizer
      The 7th Vaccine & ISV Congress
    • Place of Presentation
      Barcelona, Spain.
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Immune Regulation and Monitoring at the Epithelial Surface of the Intestine2013

    • Author(s)
      Kiyono, H.
    • Organizer
      Fondation M&eacute;rieux: Targeting Commensal Flora to Better Shape Protective Immune Responses for Better Disease Prevention and Therapy
    • Place of Presentation
      Annucy, France.
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Mucosal Connection for Immunity, Tolerance and Commensal Microbiota2013

    • Author(s)
      Kiyono, H.
    • Organizer
      JSPS: France-Japan Joint Forum “Frontiers inInnate Immunity”
    • Place of Presentation
      Strasbourg, France.
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Chaperon-Like Antigen Presentaion by Nanogel-Based Vaccine at Nasal Epithelium2011

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      Avison Biomedical Symposium 2011
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2011-02-25
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] Chaperon-Like Antigen Presentaion by Nanogel-Based Vaccine at Nasal Epithelium2011

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      Avison Biomedical Symposium 2011
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2011-02-25
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Chaperon-Like Antigen Presentaion by Nanogel-Based Vaccine at Nasal Epithelium.2011

    • Author(s)
      KIYONO H.
    • Organizer
      Avison Biomedical Symposium 2011
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2011-02-25
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Craniofacial Mucosal Immune Sysem : Uniqueness of lymphoid Organogenesis and Immunological Function for NALT and TALT2010

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      The 7^<th> Intenational Symposium on Tonsils and Mucosal Barriers of the Upper Airways
    • Place of Presentation
      Asahikawa, Hokkaido旭川グランドホテル
    • Year and Date
      2010-07-08
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] Mucosal Nanogel-based Chaperon Vaccine for the induction of protective immunity2010

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      4^<th> Vaccine and ISV Annual Global Congres
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2010-10-04
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Mucosal Immunity in the Control of Infectious Diseases2010

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      Pasteur-Areva Course Anti-Viral Imjmunity
    • Place of Presentation
      Shanghai, China
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] Novel Strategy for Mucosal Vaccine Development : MucoRice and MucoNanogel2010

    • Author(s)
      清野宏
    • Organizer
      Adaptive and Innate Immune Resposes to Neglected Tropical Disease Conference
    • Place of Presentation
      SanDiego, USA
    • Year and Date
      2010-01-10
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Intra-tissue habitation of intestinal opportunistic bacteria in mammalian gut-associated lymphoid tissues for the creation of a mucosal antibody-mediated symiosis2010

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      40^<th> Annual Meeting DGFI German Society for Immunology
    • Place of Presentation
      Leipzig, Germany
    • Year and Date
      2010-09-26
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Mucosal Immunity in the Control of Infectious Diseases2010

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      Pasteur-Areva Course Anti-Viral Imjmunity
    • Place of Presentation
      Shanghai, China
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Mucosal Nanogel-based Chaperon Vaccine for the induction of protective immunity2010

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      4^<th> Vaccine and ISV Annuals Global Congress
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2010-10-04
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] New Prospects on the Aerodigestive Immunity for Mucosal Vaccine Development2010

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      Prato Conference on the Pathogenesis of Bacterial Diseases of Animals
    • Place of Presentation
      Prato, Italy
    • Year and Date
      2010-10-09
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] Intra-Tissue habitation of commensal bacteria in Peyer's patches for gut immunity2010

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      8^<th> German-Japanease Symposium, Regulation of immune response and diseases
    • Place of Presentation
      Cuxhahen, Germany.
    • Year and Date
      2010-09-27
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] Basic principals of immune responces : innate versus adaptive immunity2010

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      The 10^<th> International Advanced Course on Vaccinology in Asia Pacific Region
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2010-05-10
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] Role of Intestinal Glycosylation for the Mucosal Immne System and Mucosal Vaccine Development2010

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      1^<st> Asia Pacific Workshop on Neurovirology Seoul 2010
    • Place of Presentation
      Seoul, Korea.
    • Year and Date
      2010-07-16
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] Intra-Tissue habitation of commensal bacteria in Peyer's patches for gut immunity.2010

    • Author(s)
      KIYONO H.
    • Organizer
      8^<th> German-Japanease Symposium, Regulation of immune response and diseases.
    • Place of Presentation
      Cuxhahen, Germany
    • Year and Date
      2010-09-27
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Role of Intestinal Glycosylation for the Mucosal Immne System and Mucosal Vaccine Development.2010

    • Author(s)
      KIYONO H.
    • Organizer
      1^<st> Asia Pacific Workshop on Neurovirology Seoul 2010
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2010-07-16
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Basic principals of immune responces : innate versus adaptive immunity2010

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      The 10^<th> International Advanced Course on Vaccinology in Asia Pacific Region
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2010-05-10
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Craniofacial Mucosal Immune Sysem : Uniqueness of lymphoid Organogenesis and Immunological Function for NALT and TALT.2010

    • Author(s)
      KIYONO H.
    • Organizer
      The 7^<th> Intenational Symposium on Tonsils and Mucosal Barriers of the Upper Airways
    • Place of Presentation
      Asahikawa., Hokkaido
    • Year and Date
      2010-07-08
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Intra-tissue habitation of intestinal opportunistic bacteria in mammalian gut-associated lymphoid tissues for the creation of a mucosal antibody-mediated symbiosis.2010

    • Author(s)
      KIYONO H.
    • Organizer
      40^<th> Annual Meeting DGFI German Society for Immunology.
    • Place of Presentation
      Leipzig, Germany
    • Year and Date
      2010-09-26
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] New Prospects on the Aerodigestive Immunity for Mucosal Vaccine Development.2010

    • Author(s)
      KIYONO H.
    • Organizer
      Prato Conference on the Pathogenesis of Bacterial Diseasesof Animals.
    • Place of Presentation
      Prato, Italy
    • Year and Date
      2010-10-09
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Mucosal Immunity in the Control of Infectious Diseases.2010

    • Author(s)
      KIYONO H
    • Organizer
      Pasteur-Areva Course Anti-Viral Imjmunity
    • Place of Presentation
      Shanghai., China
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Mucosal chaperoning nanogel vaccine for the induction of protective immunity2010

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      The 10^<th> Awaji Inteertional Forum on Infection and Immunity (United states-Japan Cooperative Medical Science Program 23^<rd> Joint Meeting of the AIDS Panels
    • Place of Presentation
      Awaji, 淡路夢舞台国際会議場
    • Year and Date
      2010-09-08
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Mucosal chaperoning nanogel vaccine for the induction of protective immunity.2010

    • Author(s)
      KIYONO H.
    • Organizer
      The 10^<th> Awaji International Forum on Infection and Immunity (United states-Japan Cooperative Medical Science Program 23rd Joint Meeting of the AIDS Panels.
    • Place of Presentation
      Awaji, Japan
    • Year and Date
      2010-09-08
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Mucosal chaperoning nanogel vaccine for the induction of protective immunity2010

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      The 10^<th> Awaji International Forum on Infection and Immunity (United states-Japan Cooperative Medical Science Program 23^<rd> Joint Meeting of the AIDS Panels
    • Place of Presentation
      Awaji, Japan.淡路夢舞台国際会議場
    • Year and Date
      2010-09-08
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] New Prospect for Mucosal Vaccine Development : MucoRiceTM for Refrigeration-and Needle/Shiringe-free vaccine.2010

    • Author(s)
      清野宏
    • Organizer
      The 2nd International Symposium of Innovative Bioproduction Kobe (iBioK)
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2010-01-22
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] New Prospect for Mucosal Vaccine Development : MucoRiceTM for Refrigeration-and Needle/Shiringe-free vaccine2010

    • Author(s)
      清野宏
    • Organizer
      The 2nd International Symposium of Innovative B-ioproduction Kobe(iBioK)
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2010-01-22
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] Craniofacial Mucosal Immune Sysem : Uniqueness of lymphoid Organogenesis and Immunological Function for NALT and TALT2010

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      The 7^<th> Intenational Symposium on Tonsilsand Mucosal Barriers of the Upper Airways
    • Place of Presentation
      Asahikawa Grand Hotel
    • Year and Date
      2010-07-08
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Mucosal Nanogel-based Chaperon Vaccine for the induction of protective immunity.2010

    • Author(s)
      KIYONO H.
    • Organizer
      4^<th> Vaccine and ISV Annual Global Congress.
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2010-10-04
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Role of Intestinal Glycosylation for the Mucosal Immne System and Mucosal Vaccine Development2010

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      1^<st> Asia Pacific Workshop on Neurovirology Seoul 2010
    • Place of Presentation
      Seoul, Korea.
    • Year and Date
      2010-07-16
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Intra-Tissue habitation of commensal bacteria in Peyer's patches for gut immunity2010

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      8^<th> German-Japanease Symposium, Regulation of immune response and diseases
    • Place of Presentation
      Cuxhahen, Germany
    • Year and Date
      2010-09-27
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] New Prospects on the Aerodigestive Immunity for Mucosal Vactine Development2010

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      Prato Conference on the Pathogenesis of Bacterial Diseasesof Animals
    • Place of Presentation
      Prato, Italy
    • Year and Date
      2010-10-09
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Basic principals of immune responces: innate versus adaptive immunity.2010

    • Author(s)
      KIYONO H.
    • Organizer
      The 10^<th> International Advanced Course on Vaccinology in Asia Pacific Region.
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2010-05-10
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Novel Strategy for Mucosal Vaccine Development : MucoRice and MucoNanogel2010

    • Author(s)
      清野宏
    • Organizer
      Adaptive and Innate Immune Resposes to Neglected Tropical Disease Conference
    • Place of Presentation
      SanDiego, USA
    • Year and Date
      2010-01-10
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] Intra-tissue habitation of intestinal opportunistic bacteria in mammalian gut-associated lymphoid tissues for the creation of a mucosal antibody-mediated symiosis2010

    • Author(s)
      HIROSHI KIYONO
    • Organizer
      40^<th> Annual Meeting DGFI German Society for Immunology
    • Place of Presentation
      Leipzig, Germany
    • Year and Date
      2010-09-26
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] The Craniofacial and Mucosal Immune System2009

    • Author(s)
      清野宏
    • Organizer
      Japanese Journal of Rhinology
    • Place of Presentation
      島根, 日本
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] New Prospect for Vaccine Development : MucoRice and MucoNanogel2009

    • Author(s)
      清野宏
    • Organizer
      3rd Vaccine Global Congress
    • Place of Presentation
      Singapore Singapore
    • Year and Date
      2009-10-04
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] New Prospect for Vaccine Development : MucoRice and MucoNanogel2009

    • Author(s)
      清野宏
    • Organizer
      3rd Vaccine Global Congress
    • Place of Presentation
      Singapore
    • Year and Date
      2009-10-04
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] 粘膜免疫による腸内細菌共生機構の構築2009

    • Author(s)
      清野宏
    • Organizer
      第63回日本細菌学会東北支部総会
    • Place of Presentation
      盛岡, 日本
    • Year and Date
      2009-08-20
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] Mucosal Decision of Immunity and Tolerance for Creation of Symbiosis2009

    • Author(s)
      清野宏
    • Organizer
      The 6th Extraordinary International Symposium on Recent Advances in Otitis Media
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-05-06
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] Mucosal Immunity : A Driving Force for the Development of New Generation of Oral Vaccine2009

    • Author(s)
      清野宏
    • Organizer
      The 13th International Conference on Emerging Infection Dieseases of the Pacific Rum : Focus on Enteric Diseases.
    • Place of Presentation
      Kolkata, India.
    • Year and Date
      2009-04-06
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Mucosal Harmony for Immunity and Tolerance in Vaccine Development2009

    • Author(s)
      清野宏
    • Organizer
      2nd European Congress of Immunology
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2009-09-14
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] MucoRice : New Horizon for the Development of Oral Vaccine2009

    • Author(s)
      清野宏
    • Organizer
      12th Asia Pacific-International Molecular Biology Network(A-IMBN)Symposium
    • Place of Presentation
      Penang, Malaysia
    • Year and Date
      2009-10-27
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] The Craniofacial and Mucosal Immune System2009

    • Author(s)
      清野宏
    • Organizer
      Japanese Journal of Rhinology
    • Place of Presentation
      島根,日本
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Mucosal Harmony for Immunity and Tolerance in Vaccine Development2009

    • Author(s)
      清野宏
    • Organizer
      2nd European Congress of Immunology
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2009-09-14
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Sessionl "Id2, RORgt, and LTbR independent initiation of TALT genesis in ocular immunity." and Sessionl "Indigenous opportunistic bacteria inhabit mammalian gut associated lymphoid tissues for gut immunity."2009

    • Author(s)
      清野宏
    • Organizer
      Mucosal immunology Workshop at Trudeau Institute
    • Place of Presentation
      New York, USA
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] Rice-Based Vaccine : New Generation of Mucosal Vacine2009

    • Author(s)
      清野宏
    • Organizer
      14th International Congress of Mucosal Immunology
    • Place of Presentation
      Boston, USA
    • Year and Date
      2009-07-08
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Mucosal Decision of Immunity and Tolerance for Creation of Symbiosis2009

    • Author(s)
      清野宏
    • Organizer
      The 6th Extraordinary International Symposium on Recent Advances in Otitis Media
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-05-06
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] 粘膜免疫による腸内細菌共生の構築2009

    • Author(s)
      清野宏
    • Organizer
      第91回日本消化器病学会 中国支部例会
    • Place of Presentation
      岡山,日本
    • Year and Date
      2009-06-13
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] 粘膜免疫による腸内細菌共生の構築2009

    • Author(s)
      清野宏
    • Organizer
      第91回日本消化器病学会中国支部例会
    • Place of Presentation
      岡山, 日本
    • Year and Date
      2009-06-13
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] Session1"Id2, RORgt, and LTbR independent initiation of TALT genesis in ocular immunity."and Session2"Indigenous opportunistic bacteria inhabit mammalian gut associated lymphoid tissues for gut immunity."2009

    • Author(s)
      清野宏
    • Organizer
      Mucosal immunology Workshop at Trudeau Institute
    • Place of Presentation
      New York, USA
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] MucoRice : New Horizon for the Development of Oral Vaccine2009

    • Author(s)
      清野宏
    • Organizer
      12th Asia Pacific-International Molecular Biology Network (A-IMBN) Symposium
    • Place of Presentation
      Penang, Malaysia
    • Year and Date
      2009-10-27
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Rice-Based Vaccine : New Generation of Mucosal Vacine2009

    • Author(s)
      清野宏
    • Organizer
      14th International Congress of Mucosal Immunol-ogy
    • Place of Presentation
      Boston, USA.
    • Year and Date
      2009-07-08
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] 粘膜免疫による腸内細菌共生機構の構築2009

    • Author(s)
      清野宏
    • Organizer
      第63回日本細菌学会 東北支部総会
    • Place of Presentation
      盛岡,日本
    • Year and Date
      2009-08-20
    • Data Source
      KAKENHI-PROJECT-20249028
  • [Presentation] Mucosal Immunity : A Driving Force for the Development of New Generation of Oral Vaccine2009

    • Author(s)
      清野宏
    • Organizer
      The 13th International Conference on Emerging In fection Dieseases of the Pacific Rum : Focus on Enteric Diseases
    • Place of Presentation
      Kolkata, India
    • Year and Date
      2009-04-06
    • Data Source
      KAKENHI-PLANNED-19059003
  • [Presentation] MucoRice: Fusion of Mucosal immunology and plant biology ked to the development of rice-based oral vaccine

    • Author(s)
      Kiyono, H
    • Organizer
      The 10th International Congress on Plant Molecular Biology
    • Place of Presentation
      Jeju , Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Vaginal resident memory T cells induced by intranasal vaccination are critical for early clearance of genital HSV-2 infection.

    • Author(s)
      Suwanto, A., Sato A., Sato S., Nochi, T., Kunisawa, J. and Kiyono, H.
    • Organizer
      The 43rd Annual Meeting of The Japanese Society for Immunology
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] “Reciprocal Cooperation of Intra-tissue Commensal Bacteria, Innate Lymphoid Cells and Mast Cells for the Integrated Mucosal Immunoregulation”

    • Author(s)
      Kiyono, H.
    • Organizer
      The 38th Aso Symposium 2014.
    • Place of Presentation
      Kumamoto, Japan.
    • Year and Date
      2014-07-25 – 2014-07-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Spick-and-Span for the Development of Transgenic-Rice (MucoRice) based Oral Vaccine

    • Author(s)
      Kiyono, H
    • Organizer
      International Union of Microbiological Societies 2011
    • Place of Presentation
      札幌、札幌コンベンションセンター
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Spick-and-Span for the Development of MucoRice and Nanoantibody for the Control of Viral and Bacterial Infection

    • Author(s)
      Kiyono, H
    • Organizer
      25th Annual Meeting of the Japanese Society for AIDS Research, International Symposium on “HIV and Mucosal Immunity”
    • Place of Presentation
      東京、ハイアットリージェンシー東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Loss of lymph node fibroblastic reticular cells and high endothelial cells underlies humoral immunodeficiency in mouse GVHD.

    • Author(s)
      Ueha, S., Suenaga, F., Abe, J., Kosugi, M., Shono, Y., Kunisawa, J., Sato S., Kiyono, H. and Matsushima, K.
    • Organizer
      The 43rd Annual Meeting of The Japanese Society for Immunology
    • Place of Presentation
      Kyoto, Japan.
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Mucosal Chaperoning Vaccines for Upper Respiratory Tract Infections

    • Author(s)
      Kiyono, H
    • Organizer
      The 14th International Rhinologic Society and 30th International Symposium on Infection and Allergy of the Nose
    • Place of Presentation
      東京、ANAインターコンチネンタル東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Mucosal Innate Immune System for Mutalisum, Inflammation and Elimination

    • Author(s)
      Kiyono, H
    • Organizer
      The 4th Microbial Pathogenesis & Immunity Symposium
    • Place of Presentation
      Seoul, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Critical role of TSLP-TSLPR interaction in inducing secretory IgA responses after mucosal immunizations.

    • Author(s)
      Joo, S., Fukuyama, Y., Yuki Y., Kurashima, Y., Ziegler, S.F., Park E-J. and Kiyono, H.
    • Organizer
      The 43rd Annual Meeting of The Japanese Society for Immunology
    • Place of Presentation
      Kyoto, Japan.
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Mucosal Integration of Mutualism and Elimination for Surface barrier System

    • Author(s)
      Kiyono, H
    • Organizer
      International Meeting of the Microbioligical Society of Korea
    • Place of Presentation
      Seoul, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] The Mucosal Gateway System for Antigen-sampling and Homestatic Niche.

    • Author(s)
      Kiyono, H
    • Organizer
      The 15th International Congress of Mucosal Immunology
    • Place of Presentation
      Paris, France
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Mucosal Vaccine for the Control of Infectious Diseases

    • Author(s)
      Kiyono, H
    • Organizer
      STS International Forum 9th Annual Meeting
    • Place of Presentation
      京都、国立京都国際会館
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Spick-and-Span in Mucosal Immunity: From Homeostasis to Vaccine Development

    • Author(s)
      Kiyono, H
    • Organizer
      Todai International Forum 2011 System Biology and Genomic Medicine Forum
    • Place of Presentation
      Paris, France
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Spick and Span in Intestional Immunity: From Mucosal Homeostasis to Vaccine Development

    • Author(s)
      Kiyono, H
    • Organizer
      The 35th General Meeting of Turkish Society of Microbiology
    • Place of Presentation
      Izmir, Turkey
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Mucosal integrated immunological seesaw between mutualization and elimination in the intestine

    • Author(s)
      Kiyono, H
    • Organizer
      The 19th East Asia Joint Symposium on Biomedical Research "Moleculer Understanding for Physiology and Pathology."
    • Place of Presentation
      Seoul, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Gut Microflora Influences Pathology in the Kawasaki Disease (KD) VasculitisMouse Model

    • Author(s)
      Wakita, D., Kurashima, Y., Takasato, Y., Lee, Y., Shimada, K., Chen, S., Crother, T. R., Fishbein, M. C., Lehman, T.J.A., Kiyono, H., and Arditi , M.
    • Organizer
      International Kawasaki Disease Symposium
    • Place of Presentation
      Hawaii, USA.
    • Year and Date
      2015-02-03 – 2015-02-06
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Mucosal Decisions of Mutualisum and Elimination for Surface barrier system

    • Author(s)
      Kiyono, H
    • Organizer
      The 6th Annual International Symposium in Institute of Dermatological Science(IDS)
    • Place of Presentation
      Seoul, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] MucoRice: Rice-based Oral Vaccine Development

    • Author(s)
      Kiyono, H
    • Organizer
      Molecular Immunology & Immunogenetics Congress 2012
    • Place of Presentation
      Antalya, Turkey
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Mucosal integreated immunological seesaw between physiological and pathological inflammation

    • Author(s)
      Kiyono, H
    • Organizer
      IEIIS 2012 Homeostatic Inflammation Symposium
    • Place of Presentation
      東京、一橋記念講堂
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Spick-and-span in mucosal vaccine development

    • Author(s)
      Kiyono, H
    • Organizer
      The 34th Naito Conference on Infection, Immunity and their Contral for Health: Mucosal Barrier, Pathogen and Vaccine
    • Place of Presentation
      札幌、シャトレーゼ ガトーキングダムサッポロ
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Resistance to helminthic infection is dependent on mast cell activation mediated by ATP in Spi-B-deficient mice.

    • Author(s)
      Shimokawa, C., Kanaya, T., Ishikawa, K., Kurashima Y., Kiyono, H., Kaisho T. and Ohno, H.
    • Organizer
      The 43rd Annual Meeting of The Japanese Society for Immunology, Kyoto
    • Place of Presentation
      Kyoto, Japan.
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] E-NPP3 (CD203c) negatively regulates ATP-dependent allergic responses by basophils and mast cells.

    • Author(s)
      Tsai, S-H., Kinoshita, M., Kayama, H., Okuma, R., Kiyono, H., Karasuyama, H. and Takeda, K.
    • Organizer
      The 43rd Annual Meeting of The Japanese Society for Immunology
    • Place of Presentation
      Kyoto, Japan.
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-23229004
  • [Presentation] Spick-and-span in Mucosal Immunity: From Intestional Homeostasis to Vaccine Develipment

    • Author(s)
      Kiyono, H
    • Organizer
      A-IMBN Symposium
    • Place of Presentation
      Jeju , Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229004
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  • 2.  TAKAHASHI Ichiro (20206791)
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  • 157.  菊田 順一
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