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Honjo Tasuku  本庶 佑

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… Alternative Names

HONJO Tasuku  本庶 佑

本庄 祐  ホンジョウ タスク

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Researcher Number 80090504
Other IDs
External Links
Affiliation (Current) 2022: 京都大学, 高等研究院, 特別教授
2022: 京都大学, 医学研究科, 特任教授
Affiliation (based on the past Project Information) *help 2022: 京都大学, 医学(系)研究科(研究院), 教授
2022: 京都大学, 学内共同利用施設等, 教授
2020 – 2021: 京都大学, 医学研究科, 特任教授
2017 – 2021: 京都大学, 高等研究院, 特別教授
2013 – 2016: 京都大学, 医学研究科, 客員教授 … More
2015: 京都大学, 医学(系)研究科(研究院), 教授
2012: 京都大学, 医学(系)研究科(研究院), 客員教授
2007 – 2011: Kyoto University, 医学研究科, 客員教授
2006: 京都大学, 医学研究科, 寄附講座教員
2005: 京大, 医学(系)研究科(研究院), 教授
1995 – 2004: 京都大学, 医学研究科, 教授
2003: Kobe University, Graduate School of Medicine, Professor, 大学院・医学研究科, 教授
2002: 京都大学, 大学院・医学系研究科, 教授
1999 – 2000: 京都大学, 大学院・医学研究科, 教授
1999: 京都大学, 大学院・医学研究科・分子生体統御学講生分子生物学, 教授
1986 – 1998: 京都大学, 医学部, 教授
1996 – 1997: Kyoto University Dept. Of Medical Chemistry. Instructor, 大学院・医学研究科, 教授
1996: 京都大学, 医・医化学, 教授
1995: 京都大学, 大学院医学研究科, 教授
1994: 京大, 医学部, 教授
1991: Center for Molecular Biology and Genetics, Kyoto University, 遺伝子実験施設, 教授
1986: 京大, 医学部, 教授
1985: 京都大学, 医, 教授 Less
Review Section/Research Field
Principal Investigator
General medical chemistry / Biological Sciences / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Immunology / Immunology / General medical chemistry
Except Principal Investigator
内科学一般 / Anthropology / Pathological medical chemistry / Immunology … More / Biological Sciences / Basic Section 54010:Hematology and medical oncology-related / Immunology / 膠原病・アレルギー・感染症内科学 / General medical chemistry / 寄生虫学(含医用動物学) / Virology / Immunology / Basic Section 50020:Tumor diagnostics and therapeutics-related Less
Keywords
Principal Investigator
クラススイッチ / PD-1 / 体細胞突然変異 / RNA編集 / DNA結合タンパク質 / ショウジョウバエ / SーS組換え / AID / 環状DNA / 免疫グロブリン遺伝子 … More / DNA切断 / 組換え / 獲得免疫 / RBP-Jk / subtraction hybridization / fibrillin 1 / PD-L2 / SHP-2 / PD-L1 / Notch / RBP-J / Mint / VDJ組換え / 神経分化 / 突然変異 / PD-L / IMCT法 / LDL受容体 / グルタミン酸受容体 / SPA-1 / パーキンソン / 立体構造 / ウラシルDNAグリコシラーゼ / 免疫沈降法 / マイクロアレイ法 / 免役学 / 抗体 / ゲノム / 癌 / Bリンパ球 / VDJ組換 / 骨髄多分化能細胞 / ストロ-マ細胞 / リコンビナ-ゼ / 抗体遺伝子再構成 / cDNAクローニング / integrase family / transgenic mouse / double isotype expression / trans splicing / ヒト抗体V_H鎖遺伝子 / 骨髄細胞からのリンパ球への分化 / IgM^+IgG^+B細胞 / IL-2 / IL-2R / トランスジュニックマウス / NK細胞 / 抗体遺伝子D断片 / Bリンパ球の分化 / IL-4 / IL-2リセプター / トランスジェーニックマウス / 染色体マップ / IL-4遺伝子 / IL-5遺伝子 / リンフォカイン遺伝子 / 人工突然変異 / インターロイキン2の受容体 / インターロイキン5 / エンハンサー / クラススイッチ組換え / DNA修復 / 免疫帰国 / 大規模シークエンス / FACT複合体 / 抗体遺伝子 / 遺伝子組換え / germline転写物 / インタ-ロイキン4 / immunoglobulin gene / class switch / rearrangement / germline transcript / interleukin 4 / circular DNA / ES細胞 / 共生細胞 / 血球分化 / 細胞死 / RBP-Jκ / EBウイルス / 情報伝達 / 転写因子 / ミニ染色体 / CD40 / 遺伝子破壊マウス / Apoptosis / 計画的細胞死 / 自己免疫 / gene knock-out / クローン欠失 / conculture / ES cells / programd cell death / knock out / EBNA2 / S領域 / 培養細胞株 / 人工プラスミド / ジャーミナルセンター / 塩基配列 / B染色体 / PCR / sequencing / transfection / S-region / cultured cell line / artificial plasmid / germinal center / nucleotide sequence / 進行性全身性強皮症 / TSKマウス / fibrillin1 / 変異型fibrillin1 / 進行性全身強皮症 / 変異型fibrillin 1 / progressive systemic sclerosis / TSK mice / mutated fibrillin 1 / 自己免疫疾患 / DP-L1 / Autoimmunity / 細胞運命決定 / 細胞分化 / リンパ球分化 / 遺伝子欠損マウス / Cell fate decision / Cell differentiation / Lymphocyte development / Knockout mouse / ヒト【V_H】遺伝子 / endonulease-J / T細胞受容体遺伝子 / IL-2受容体遺伝子 / B細胞増殖因子(IL-4)遺伝子 / 免疫記憶 / 獲免免疫 / トポイソメラーゼ1 / トポイソメラーゼ 1 … More
Except Principal Investigator
自己免疫疾患 / シグナル伝達 / PD-1 / サイトカイン / 免疫寛容 / 免疫制御 / 自己免疫病 / Notch / 免疫グロブリン遺伝子 / トランスジェニックマウス / リンパ系腫瘍 / DNA診断 / cytokine / signal transduction / autoimmune disease / 免疫病 / 免疫表現型 / 免疫遺伝子型 / 二重遺伝子型 / 免疫関連遺伝子再構成 / 細胞産生因子遺伝子転写 / 産業経済 / 自然と人工 / 転写因子 / LPS / B70 / 免疫応答 / IL-10 / B細胞 / 発生工学 / PCR / DNA / CH12 / MHC / 免疫異常 / IAP / IRB / PD-L1 / シナプス伝達制御 / グルタミン酸受容体 / クラススイッチの分子機構 / PD-1による免疫制御 / 幹細胞ニッチ / ES細胞 / MAPキナーゼ / 高次脳機能 / 幹細胞の分化 / 初期発生 / 試験管内発生・分化制御 / MAPキナーゼファミリー / キナーゼカスケード / 記憶・学習 / 血球分化・増殖因子 / 抗体クラススイッチ / 受容体型チロシンキナーゼ / 細胞内シグナル伝達 / 細胞死 / AID / 免疫記憶 / Bリンパ球 / 胚中心 / processing / プロテアーゼ阻害剤 / MG132 / プロテアソーム 阻害剤 / Lactacystin / カルパイン / Delta / TSHレセプター / 抗TSHレセプター抗体 / バセドウ病 / トランスジェニツクマウス / レプチン / B-1細胞 / 胸腺細胞 / 膠原病学 / ループス腎炎 / トレランス / マイクロRNA / NZB / W F1 / ループス賢炎 / 分化抗原 / T細胞受容体遺伝子 / 免疫系遺伝子再編成 / 不死化;myc遺伝子 / ras遺伝子 / 初代細胞 / トランスホーメーション / 初期胎児組織 / ショウジョウバエの劣性腫瘍遺伝子 / IL-2レセプターの発現 / 人類の系統と起源 / 霊長類の系統と分類 / 分子生物学 / 行動 / 霊長類社会 / 遺伝学 / 運動様式 / ウィルス / T・B細胞分化 / 血球細胞分化 / プロB細胞 / プロT細胞 / DNAメチル化 / T細胞抗原受容体遺伝子 / リンパ球分化 / サイトカインレセプタ- / RAG1 / 抗体のプロセッシング / ス-パ-抗原 / Cytokine receptor / RAG 1 / Antigen processing / Superantigen / Autoimmune disease / 自然と人間生活 / 文化人類学 / 文化交流 / 学際研究 / 環境と資源問題 / 21世紀の都市のイメージ / EC統合 / 自然と人為 / 日伊関係 / 文学・芸術・生活 / ルネッサンス / クロスカルチャ- / Nature and human life / Industrial economics / Anthropology / Cross culture / Interdisciplinary research / Nature and artifact / Environmental and resources constraint / Image of cities in 21st century / リンパ球 / レセプター / 遺伝子発現 / 主要組織適合抗原 / lymphocytes / receptor / transcription factor / gene expression / autoimmune diseases / major histocompatibility antigen / 遺伝子導入マウス / CD5陽性B(B-1)細胞 / 溶血性貧血 / 腹腔B細胞 / 消化管免疫 / プログラム細胞死 / CD5陽性B細胞 / B細胞トレランス / 腸管内抗原 / Transgenic mouse / CD5^+ B cells (B-1 cells) / B cells in abdominal cavity / Auto-immune disease / Hemolytic anemia / Gastro-intestinal immunity / Programd cell death / 自己トレランス / アポプトーシス / CD5^+B細胞 / 接着分子 / MHC分子 / 抗原ペプチド / self-tolerance / apoptosis / CD5^+B cells / adhesion molecule / MHC molecule / antigenic peptide / 京都 / シエナシンポジウム / 自然科学部門 / 文学・芸術・人間学部門 / 法・経済学部門 / 岩倉使節団展 / 盆栽と写真展 / レオナルド以前展覧会 / レオナルド以前のレオナルド展覧会 / 学際領域研究 / 人間生活 / 人間学 / 異文化交流 / 文化交流人類学 / イメージ / Kyoto / Siena Symposium / Science Session / Humanity Session / Law / Economy Session Diplomatic Mission Exhibition / Bonsai and Artistic Photo Exhibition Prima di Leonardo Exhibition / Leonardo Prima di Leonardo Exhibition / 総括班 / 情報提供 / 情報交換 / 国際シンポジウム / ジーンノックアウトマウス / immune regulation / immune tolerance / group of generalization / providing information / information exchanges / international symposium / transgenic mouse / gene knockout mouse / alyマウス / 外分泌腺炎 / シェ-グレン症候群 / CD4陽性T細胞 / 動物モデル / 慢性膵炎 / 自己免疫 / aly mouse / exocrine organs / Sjogren's syndrome / CD4^+ T cells / animal model / chronic pancreatitis / 遺伝子クローニング / 造血細胞 / マウス / 分泌蛋白 / 造血 / cDNA cloning / hematopoiesis / mice / secretory proteins / T細胞 / ポリコ-ム遺伝子 / 水晶体特異的遺伝子発現 / 有機リン系農薬センサー / T cell / Immunological tolerance / B cell / Transgenics / Polycomb genes / Crystallin gene / Biosensor / Transcriptional factor / 免疫グロブリン / アイソタイプ / スイッチ / 組換え / スイッチ領域 / 抗体 / 遺伝子 / 組み換え / Immunoglobulin / Isotype / Switch / Recombination / S-region / CD40, CD40L / CD80, CD86 / HSI / CD95L / IL-6 / 脳性マラリア / 毛細血管閉塞 / 皮下組織 / 胃粘膜内pH / マラリアワークショップ / Quinghaosu / Artesnate / Deferoxamine Antagonism / Cerebral malaria / Deferoxamine / Antagonism / 胃粘膜 / 毛細血管 / cerebral malaria / sequestration / subcutaneous tissues / intra mucosa gastric pH / qinghaosue / deferoxamine / artesnate / レパートリー形成 / 免疫識別の多型性 / 免疫識別の多様性 / 情報伝達 / リンパ球の機能分化 / 免疫病とその修復 / 新しい診断法 / 免疫職別の多型性 / 免疫職別の多様性 / MHCと抗原ペプチド / 抗原レセプター / アレルギー / 免疫病の分子機構 / 自己認識 / 免疫不全 / Repertoire selection / Antigen receptor / Immunodiversity / Tyrosine kinase / Inflammation / Immunological disorders / Signal transduction / IL-5 / マウス乳癌ウイルス / ウイルス発癌 / 白血病 / マウス白血病ウイルス / notch / Mouse Mammary Tumor Virus / Viral Oncology / Lymphoma / Murine leukemia Virus / 抗原受容体 / 補助受容体 / 細胞分化 / 炎症疾患 / ノックアウトマウス / immune response / antigen receptor / co-receptor / cell differentiation / inflammation / 生殖細胞 / 哺乳類 / 生殖系列 / Germ cells / mammalian / embryo manipulation / germ lineage / 高度先端医療 / トランスレーショナル・リサーチ / 国立大学医学部 / 高度先端医療開発センター / 産官学連携体制 / 高度先進医療 / Evidence based medicine / マッチング機構 / Advanced Medical Development / Translational research / Medical school of national university / Advanced Medical development center / systems of joint industry-academia research / 抑制性レセプター / 自己抗体 / 自己抗原 / 拡張型心筋症 / Negative receptors / Autojmmune diseases / Autoantibody / Antoantigen / Dilated cardiomyopathy / PDリガンド / 関節リウマチ / 共刺激分子 / 滑膜細胞 / 関節炎 / 関節組織 / コラーゲン誘導関節炎 / 関節液 / PD ligand / rheumatoid arthritis / co-stimulatory molecule / synovial cell / arthritis / collagen-induced arthrits / ニホンザルの集団構造 / 遺伝的浮動 / テナガザルの系統分類 / DNA解析 / 二足走行 / 人種分化 / 歯の形態 / ヒト上科 / 二足歩行 / ヒト上科の遺伝的系統図 / 霊長類の遺伝子地図 / 霊長類の染色体 / population structure of Japanese macaque / genetic drift / phylogeny of gibons / DNA analysis / bipedalism / differentiation of human races / morphological character of tooth / hominoidea / cancer immunotherapy / PD-1 blockade Less
  • Research Projects

    (55 results)
  • Research Products

    (125 results)
  • Co-Researchers

    (200 People)
  •  ワクチン接種による抗体産生に必須なAID-recombinosome形成機構解明Principal Investigator

    • Principal Investigator
      本庶 佑
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      Kyoto University
  •  EBV抗原発現調節による、EBV関連胃癌に対する効果的ながん免疫療法の開発Host Researcher

    • Host Researcher
      本庶 佑
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyoto University
  •  Mechanistic analysis of the PD-1 blockade combination cancer immunotherapy with BTK inhibitors.Host Researcher

    • Host Researcher
      本庶 佑
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Kyoto University
  •  BTK阻害剤とPD-1抗体のがん免疫併用治療における効果増強メカニズムの解析Host Researcher

    • Host Researcher
      本庶 佑
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Kyoto University
  •  AIDのRNA編集による抗体遺伝子多様化機構の解明Principal Investigator

    • Principal Investigator
      本庶 佑
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      Kyoto University
  •  Boosting PD-1 blockade cancer immunotherapy by modulating T cell metabolismHost Researcher

    • Host Researcher
      本庶 佑
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Immunology
    • Research Institution
      Kyoto University
  •  Regulatory mechanism of immunoglobulin diversification and genome instability through RNA-editing by AIDPrincipal Investigator

    • Principal Investigator
      Honjo Tasuku
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      General medical chemistry
    • Research Institution
      Kyoto University
  •  Mechanism for genome instability by activation induced cytidine deaminase induced-reduction of topoisomerase1Principal Investigator

    • Principal Investigator
      HONJO Tasuku
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  抗体産生免疫記憶細胞が生ずる分子機構の解明Host Researcher

    • Host Researcher
      本庶 佑
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Immunology
    • Research Institution
      Kyoto University
  •  MicroRNA profiling of human lupus nephritis and murine lupus-like nephritis.

    • Principal Investigator
      KAWANO Seiji
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Kobe University
  •  AID-dependent genetic alteration mechanism to generate antigen-specific antibodiesPrincipal Investigator

    • Principal Investigator
      HONJO Tasuku
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  AIDによるゲノム情報改編機構の研究Principal Investigator

    • Principal Investigator
      本庶 佑
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Kyoto University
  •  Regulation of lymphocyte development by Notch/RBP-J signalingPrincipal Investigator

    • Principal Investigator
      HONJO Tasuku
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      Kyoto University
  •  Role of PD-1/PD ligand system in the pathogenesis of rheumatoid arthritis

    • Principal Investigator
      KUMAGAI Shunichi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      Kobe University
  •  Mechanism for autoimmune dilated cardiomyopathy in PD-1-deficient mice

    • Principal Investigator
      MINATO Nagahiro
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      KYOTO UNIVERSITY
  •  獲得性生体情報の構築・応答ならびにその異常と病態の研究Principal Investigator

    • Principal Investigator
      本庶 佑
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for COE Research
    • Research Institution
      Kyoto University
  •  Isolation of PD-1 ligands and their application for immunosuppressionPrincipal Investigator

    • Principal Investigator
      HONJO Tasuku
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      KYOTO UNIVERSITY
  •  自己免疫病発症に関与するB-1細胞の発生分化活性化機構の解明

    • Principal Investigator
      村上 雅朗
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Research Institute for Production Development
  •  Regulatory mechanism of signal transduction in the immune system.

    • Principal Investigator
      HIRANO Toshio
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Regulative Mechanisms and Manipulation of the Germ Cell Lineage

    • Principal Investigator
      NAKATSUJI Norio
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      KYOTO UNIVERSITY
  •  Study for the ways to promote systematic, advanced medical research

    • Principal Investigator
      SUGIMACHI Keizou
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Special Purposes
    • Research Institution
      KYUSHU UNIVERSITY
  •  Notch細胞質領域のリガンド依存的な切断部位の特定、及びプロテアーゼの同定

    • Principal Investigator
      黒岡 尚徳
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyoto University
  •  免疫グロブリン遺伝子導入マウスを利用したヒト型高親和性抗体の作製と抗体遺伝子解析

    • Principal Investigator
      赤水 尚史
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      内科学一般
    • Research Institution
      Kyoto University
  •  Molecular analysis of TSK mouseas a model of sclerodermaPrincipal Investigator

    • Principal Investigator
      HONJO Tasuku
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General medical chemistry
    • Research Institution
      KYOTO UNIVERSITY
  •  Functional analysis of truncated Notch 1 gene products generated by insertions of mouse mammary tumor proviruses in development of mouse lymphomas.

    • Principal Investigator
      YANAGAWA Shin-ichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      KYOTO UNIVERSITY
  •  Regulation of Gene Expression

    • Principal Investigator
      TANIGUCHI Masaru
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University, School of Medicine
  •  Joint Project for the Investigation of Molecular Mechanism of Class Switch Recombination

    • Principal Investigator
      KONDOH Shigeru
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      KYOTO UNIVERSITY
  •  Immune regulation and signal tranduction

    • Principal Investigator
      OKUMURA Ko
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Juntendo University School of Medicine
  •  The Pathogenesis of Severe Malaria

    • Principal Investigator
      AIKAWA Masamichi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Tokai University
  •  Molecular Mechanisms and Intervention of Immunological Diseases.

    • Principal Investigator
      TAKATSU Kiyoshi
    • Project Period (FY)
      1996 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  高次生体システムの機能制御の研究.

    • Principal Investigator
      中西 重忠
    • Project Period (FY)
      1995 – 1999
    • Research Category
      Grant-in-Aid for COE Research
    • Research Institution
      Kyoto University
  •  Molecular Mechanism for the Class Switch Recombination of immunoglobulin GenePrincipal Investigator

    • Principal Investigator
      HONJO Tasuku
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      KYOTO UNIVERSITY
  •  Establishment of a spontaneous single gene model for Sjogren's syndrome

    • Principal Investigator
      TSUBATA Takeshi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      Tokyo Medical and Dental University
      Kyoto University
  •  Practical Improvement of Signal Sequence Trap Method

    • Principal Investigator
      NAKANO Toru
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
  •  Studies on molecular mechanisms of autoimmune diseases

    • Principal Investigator
      KISHIMOTO Tadamitsu
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University
  •  JAPAN-ITALY PROGRAM ON FRONTIER FIELDS -NATURE AND HUMAN LIFE-

    • Principal Investigator
      IMANISHI Yukio
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kyoto University
  •  Molecular mechanism of immune regulation and immune tolerance

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  免疫制御・寛容の分子機構

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Institution
      Kyushu University
  •  Studies on the regulation of gene expression in lymphoid cells.

    • Principal Investigator
      KISHIMOTO Tadamitsu
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University
  •  Mechanisn of lymphocyte differentiation, molecular mechanisms of gene rearrangement and clonal deletion by antigenesPrincipal Investigator

    • Principal Investigator
      HONJO Tasuku
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Research Institution
      KYOTO UNIVERSITY
  •  Development of a method for regulation of auto-reactive B cells using transgenic mouse carrying genes encoding an anti-self-erythrocyte antibody.

    • Principal Investigator
      SHIMIZU Akira
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      KYOTO UNIVERSITY
  •  Bリンパ球の運命づけの過程における抗体遺伝子の再構成の制御Principal Investigator

    • Principal Investigator
      本庶 佑
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Kyoto University
  •  Studies on the regulation of gene expression in lymphoid cells.

    • Principal Investigator
      KISHIMOTO Tadamitsu
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University
  •  Japan-Italy Program on Frontier Fields Nature and Human Life

    • Principal Investigator
      IMANISHI Yukio
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kyoto University
  •  Molecular mechanisms for immunoglobulin class switchingPrincipal Investigator

    • Principal Investigator
      HONJO Tasuku
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Center for Molecular Biology and Genetics, Kyoto University
  •  リンパ系腫瘍の免疫関連遺伝子および細胞産生因子遺伝子発現と病態に関する研究

    • Principal Investigator
      白川 茂
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Mie University
  •  リンパ球細胞のTーおよびBー細胞への分化決定機構の解明

    • Principal Investigator
      川市 正史
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Kyoto University
  •  Evolution of primate and origin of man.

    • Principal Investigator
      NOZAWA K.
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Anthropology
    • Research Institution
      KYOTO UNIVERSITY
  •  リンパ系腫瘍の免疫関連遺伝子および細胞産生因子遺伝子発現に関する研究

    • Principal Investigator
      白川 茂
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Mie University
  •  米国西海岸地域における分子免疫生物学の進捗に関する調査研究

    • Principal Investigator
      岸本 忠三
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Overseas Scientific Research
  •  リンパ系腫瘍の分化抗原発現と免疫グロブリン及びT細胞受容体遺伝子再編成の解析

    • Principal Investigator
      白川 茂
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Mie University
  •  細胞の不老不死と腫瘍遺伝子による試験管内発がんの関連

    • Principal Investigator
      近藤 宗平
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kinki University
  •  免疫系における多様性発現機構の分子遺伝学的研究Principal Investigator

    • Principal Investigator
      本庶 佑
    • Project Period (FY)
      1986 – 1990
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Research Institution
      Kyoto University
  •  人類の起源と系統をめぐる分子進化の研究推進

    • Principal Investigator
      EHARA A.
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Anthropology
    • Research Institution
      Kyoto University
  •  リンパ球分化過程における抗体遺伝子の再構成と情報発現調節機構Principal Investigator

    • Principal Investigator
      本庶 佑
    • Project Period (FY)
      1982 – 1985
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Research Institution
      Kyoto University
      Osaka University

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

  • [Book] ゲノムが語る生命像2012

    • Author(s)
      本庶 佑
    • Total Pages
      259
    • Publisher
      講談社
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Book] いのちとはなにか-幸福・ゲノム・病2009

    • Author(s)
      本庶佑
    • Total Pages
      154
    • Publisher
      岩波書店
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Book] Discovery of activation-induced cytidine deaminase, the engraver of antibody memory. Vol.942007

    • Author(s)
      Muramatsu, M., Nagaoka, H., Shinkura, R., Begum, N.A., Honjo, T.
    • Publisher
      ELSEVIER, Adv. Immunol.
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Book] Role of AID in tumorigenesis.,Vol.942007

    • Author(s)
      Okazaki, I., Kotani, A. Honjo, T.
    • Publisher
      ELSEVIER, Adv. Immunol.
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Journal Article] SAMHD1-mediated dNTP degradation is required for efficient DNA repair during antibody class switch recombination2020

    • Author(s)
      Husain Afzal、Xu Jianliang、Fujii Hodaka、Nakata Mikiyo、Kobayashi Maki、Wang Ji‐Yang、Rehwinkel Jan、Honjo Tasuku、Begum Nasim A
    • Journal Title

      EMBO J.

      Volume: 39

    • DOI

      10.15252/embj.2019102931

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07547, KAKENHI-PROJECT-19H01027
  • [Journal Article] Antibody class switch recombination requires SAMHD1-mediated dNTP degradation to promote DNA repair2020

    • Author(s)
      Afzal Husain, Jiangling Xu, Hodaka Fuji, Mikiyo Nakata, Kobayashi Maki, Ji- Yang Wang, Jan Rehwinkel, Tasuku Honjo, Nasim A. Begum
    • Journal Title

      EMBO J.

      Volume: under revision

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H01027
  • [Journal Article] RNA-binding motifs of hnRNP K are critical for induction of antibody diversification by activation-induced cytidine deaminase2020

    • Author(s)
      Ziwei Yina, Maki Kobayashi, Wenjun Hu, Koichi, Higashi, Nasim A. Begum, Ken Kurokawa and Tasuku Honjo
    • Journal Title

      PNAS

      Volume: in press Pages: 11624-11635

    • DOI

      10.1073/pnas.1921115117

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06485, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-19H01027
  • [Journal Article] Apurinic/apyrimidinic endonuclease 1 (APE1) is dispensable for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation in the immunoglobulin gene.2019

    • Author(s)
      Helena Islam, Maki Kobayashi and Tasuku Honjo.
    • Journal Title

      International Immunology

      Volume: --

    • DOI

      10.1093/intimm/dxz028

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05784, KAKENHI-PROJECT-16K07251
  • [Journal Article] PPAR-induced fatty acid oxidation in T cells ameliorates the antitumor activity of PD-1 blockade by increasing the number of tumor-reactive CD8+ T cells2018

    • Author(s)
      Chowdhury, P. S., Chamoto, K., Kumar. A., Honjo, T
    • Journal Title

      Cancer Immunology Research

      Volume: 6 Pages: 1375-1387

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17119
  • [Journal Article] Depletion of recombination-specific cofactors by the C-terminal mutant of the activation-induced cytidine deaminase causes the dominant negative effect on class switch recombination2017

    • Author(s)
      Al Ismail, A., Husain, A., Kobayashi, M., Honjo, T., Begum, N. A.
    • Journal Title

      International Immunology

      Volume: 29 Pages: 525-537

    • DOI

      10.1093/intimm/dxx061

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07214, KAKENHI-PROJECT-15H05784, KAKENHI-PROJECT-16K07251
  • [Journal Article] Chromatin remodeler SMARCA4 recruits topoisomerase I and suppresses transcription associated genomic instability.2016

    • Author(s)
      Husain, A. Begum, N. A., Kobayashi, M. and Honjo, T.
    • Journal Title

      Nature Communication

      Volume: 7 Pages: 00-00

    • DOI

      10.1038/ncomms10549

    • NAID

      120005745627

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25440007, KAKENHI-PROJECT-22000015, KAKENHI-PROJECT-16K07214
  • [Journal Article] Chromatin remodeler SMARCA4 recruits topoisomerase 1 and suppresses transcription associated genomic instability.2016

    • Author(s)
      Husain, A. Begum, N. A., Kobayashi, M. and Honjo, T.
    • Journal Title

      Nature Communications

      Volume: なし Pages: 1-15

    • NAID

      120005745627

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Journal Article] Functional requirements of AID's higher-order structure and interaction with RNA-binding proteins.2016

    • Author(s)
      Mondal, S., Begum, N. A., Hu, W. and Honjo, T.
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: early edition Pages: 1545-1554

    • DOI

      10.1073/pnas.1601678113

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22000015, KAKENHI-PROJECT-15H05784, KAKENHI-PROJECT-16K07214
  • [Journal Article] Identification of DNA cleavage- and recombination-specific hnRNP co-factors for Activation-induced cytidine deaminase2015

    • Author(s)
      Hu W, Begum NA, Mondal S, Stanlie A and Honjo T
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: in press Pages: 5791-5796

    • DOI

      10.1073/pnas.1506167112

    • Description
      【掲載確定】 in press
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590352, KAKENHI-PROJECT-22000015, KAKENHI-PROJECT-15H05784
  • [Journal Article] Identification of DNA cleavage- and recombination-specific hnRNP co-factors for Activation-induced cytidine deaminase.2015

    • Author(s)
      Hu, W., Begum, N. A., Mondal, S., Stanlie, A. and Honjo, T.
    • Journal Title

      Proc. Nat1. Acad. Sci. USA

      Volume: 112 Pages: 5791-5796

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Journal Article] ) C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion.2014

    • Author(s)
      Sabouri S, Kobayashi M, Begum NA, Xu J, Hirota K, Honjo T
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 111 Pages: 2253-2258

    • DOI

      10.1073/pnas.1324057111

    • NAID

      120005395696

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23221005, KAKENHI-PUBLICLY-24114509, KAKENHI-PROJECT-24590352, KAKENHI-PROJECT-25281021, KAKENHI-PROJECT-25440007, KAKENHI-PROJECT-22000015
  • [Journal Article] APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination2014

    • Author(s)
      Jianliang Xu, Afzal Husain, Wenjun Hu, Tasuku Honjo and Maki Kobayashi.
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 111 Pages: 17242-17247

    • DOI

      10.1073/pnas.1420221111

    • Description
      【掲載確定】
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25440007, KAKENHI-PROJECT-22000015
  • [Journal Article] Activation-induced cytidine deaminase is dispensable for virus-mediated liver and skin tumor development in mouse models2014

    • Author(s)
      Nguyen T, Xu J, Chikuma S, Hiai H, Kinoshita K, Moriya K, Koike K, Marcuzzi GP, Pfister H, Honjo T, Kobayashi M.
    • Journal Title

      Int. Immunol.

      Volume: 26 Pages: 397-406

    • DOI

      10.1093/intimm/dxu040

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390183, KAKENHI-PROJECT-25440007, KAKENHI-PROJECT-25460363, KAKENHI-PROJECT-22000015
  • [Journal Article] Chromatin Reader Brd4 Functions in Ig Class Switching as a Repair Complex Adaptor of Nonhomologous End-Joining2014

    • Author(s)
      Stanlie A, Yousif AS, Akiyama H, Honjo T and Begum NA.
    • Journal Title

      Mol. Cell

      Volume: 55(1) Pages: 97-110

    • DOI

      10.1016/j.molcel.2014.05.018

    • Description
      【掲載確定】
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590352, KAKENHI-PROJECT-22000015
  • [Journal Article] Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase.2014

    • Author(s)
      Yousif AS, Stanlie A, Mondal S, Honjo T, Begum NA.
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 111

    • DOI

      10.1073/pnas.1402391111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590352, KAKENHI-PROJECT-22000015
  • [Journal Article] Opinion : uracil DNA glycosylase(UNG)plays distinct and non-canonical roles in somatic hypermutation and class switch recombination2014

    • Author(s)
      Yousif AS, Stanlie A, Begum NA and Honjo T
    • Journal Title

      Int. Immunol.

      Volume: 26(10) Pages: 575-578

    • DOI

      10.1093/intimm/dxu071

    • Description
      【掲載確定】
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590352, KAKENHI-PROJECT-22000015
  • [Journal Article] The AID Dilemma : Infection, or Cancer?2013

    • Author(s)
      Tasuku Honjo, Maki Kobayashi, Nasim Begum, Ai Kotani, Somayeh Sabour and Hitoshi Nagaoka
    • Journal Title

      Adv.Cancer Res.

      Volume: vol.113 Pages: 1-44

    • DOI

      10.1016/b978-0-12-394280-7.00001-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570169, KAKENHI-PUBLICLY-23118513, KAKENHI-PROJECT-23659151, KAKENHI-PROJECT-24590352, KAKENHI-PROJECT-22000015
  • [Journal Article] FACT and H3.3 : New markers for the somatic hypermutation.2013

    • Author(s)
      Aida M, Hamad N, Stanlie A, Begum NA, Honjo T.
    • Journal Title

      Cell Cycle

      Volume: 110 Pages: 2923-2924

    • DOI

      10.1073/pnas.1305859110

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590352, KAKENHI-PROJECT-22000015
  • [Journal Article] Evolutionary comparison of the mechanism of DNA cleavage with respect to immune diversity and genomic instability.2012

    • Author(s)
      Begum, N.A. and Honjo, T.
    • Journal Title

      Biochemistry

      Volume: 51 Pages: 5243-5256

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Journal Article] B cell-specific and stimulation-responsive enhancers derepress the Aicda gene by overcoming the effects of silencers.2010

    • Author(s)
      Tran, T., Nakata, M., Suzuki, K., Begum, N.A., Shinkura, R., Fagarasan, S., Honjo, T., Nagaoka, H.
    • Journal Title

      Nature Immunol. 11

      Pages: 148-154

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Journal Article] AID-induced T-lymphoma or B-leukemia/lymphoma in a mouse BMT model.2010

    • Author(s)
      Komeno, Y., Kitaura, J., Watanabe-Okochi, N., Kato, N., Oki, T., Nakahara, F., Harada, Y., Harada, H., Shinkura, R., Nagaoka, H., Hayashi, Y., Honjo, T., Kitamura, T.
    • Journal Title

      Leukemia 24

      Pages: 1018-1024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Journal Article] Apex2 is required for efficient somatic hypermutation but not for class switch recombination of immunoglobilin genes.2009

    • Author(s)
      Sabouri, Z., Okazaki, I., Shinkura, R., Begum, N.A., Nagaoka, H., Tsuchimoto, D., Nakabeppu, Y., Honjo, T.
    • Journal Title

      Int.Immunol. 21

      Pages: 947-955

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Journal Article] The C-terminal region of AID is responsible for a novel function other than DNA cleavage in class switch recombination.2009

    • Author(s)
      Doi, T., Kato, L., Ito, S., Shinkura, R., Wei, M., Nagaoka, H., Wang, J., Honjo, T.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 106

      Pages: 2758-2763

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Journal Article] Carboxy-terminal domain of AID required for its mRNA complex formation in vivo.2009

    • Author(s)
      Nonaka, T., Doi, T., Toyoshima, T., Muramatsu, M., Honjo, T., Kinoshita, K.
    • Journal Title

      Natl.Acad.Sci.USA 106

      Pages: 2747-2751

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Journal Article] AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination.2009

    • Author(s)
      Kobayashi, M., Aida, M., Nagaoka, H., Begum, N.A., Kitawaki, Y., Nakata, M., Stanlie, A., Doi, T., Kato, L., Okazaki, I., Shinkura R., Muramatsu, M., Kinoshita, K., Honjo, T.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 106

      Pages: 22375-22380

    • NAID

      120001749564

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Journal Article] Further evidence for involvement of a non-canonical function of uracil DNA glycosylase in class switch recombination.2009

    • Author(s)
      Begum, N.A., Stanlie, A., Doi, T., Sasaki, Y., Jin, H.W., Kim, Y.S., Nagaoka, H., Honjo, T.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 106

      Pages: 2752-2757

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Journal Article] Dissociation of in vitro DNA deamination activity and physiological functions of AID mutants.2008

    • Author(s)
      Shivarov, V., Shinkura, R., Honjo, T.
    • Journal Title

      Proc.Natl.Acad.Sci.USA. 105

      Pages: 15866-15871

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Journal Article] Morse, HC 3rd, Nussenzweig, MC and Dalla-Favera, R.AID is required for germinal center-derived lymphomagenesis.2008

    • Author(s)
      Pasqualucci, L., Bhagat, G., Jankovic, M., Compagno, M., Smith, P., Muramatsu, M., Honjo, T.
    • Journal Title

      Nat.Genet. 40

      Pages: 108-112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Journal Article] Nature Immunol.A memoir of AID, which engraves antibody memory on DNA.2008

    • Author(s)
      Honjo, T.
    • Journal Title

      Nature Immunol. 9

      Pages: 335-337

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Journal Article] A memoir on AID, which engraves antibody memory on DNA.2008

    • Author(s)
      Honjo, T.
    • Journal Title

      Nature Immunol. 9

      Pages: 335-337

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Journal Article] A memoir of AID, which engraves antibody memory on DNA.2008

    • Author(s)
      Honjo, T.
    • Journal Title

      Nature Immunol. 9

      Pages: 335-337

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Journal Article] Requirement of non-canonical activity of uracil DNA glycosylase for class switch recombination.2007

    • Author(s)
      Begum, N.A., Izumi, N., Nishikori, M., Nagaoka, H., Shinkura, R., Honjo, T.
    • Journal Title

      J.Biol.Chem. 282

      Pages: 731-742

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Journal Article] Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium.2007

    • Author(s)
      Matsumoto, Y., Marusawa, H., Kinoshita, K., Endo, Y., Kou, T., Morisawa, T., Azuma, T., Okazaki, I., Honjo, T., Chiba, T.
    • Journal Title

      Nature Medicine 13

      Pages: 470-476

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Journal Article] Discovery of activation-induced cytidine deaminase, the engraver of antibody memory.2007

    • Author(s)
      Muramatsu, M., Nagaoka, H., Shinkura, R., Begum, N.A., Honjo, T.
    • Journal Title

      Adv.Immunol. 94

      Pages: 1-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Journal Article] Role of AID in tumorigenesis.2007

    • Author(s)
      Okazaki, I., Kotani, A., Honjo, T.
    • Journal Title

      Adv.Immunol. 94

      Pages: 245-273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Journal Article] AID to overcome the limitations of genomic information.2005

    • Author(s)
      Honjo, T., Nagaoka, H., Shinkura, R., Muramatsu, M.
    • Journal Title

      Nature Immunol. 6

      Pages: 655-661

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Journal Article] AID : how does it aid antibody diversity?2004

    • Author(s)
      Honjo, T.
    • Journal Title

      Immunity 20

      Pages: 707-712

    • Data Source
      KAKENHI-PROJECT-12CE2006
  • [Presentation] Serendipities of acquired immunity2019

    • Author(s)
      本庶 佑
    • Organizer
      第119回日本外科学会定期学術集会 特別講演
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01027
  • [Presentation] 獲得免疫の驚くべき幸運(Serendipities of acquired immunity)2019

    • Author(s)
      本庶 佑
    • Organizer
      第78回日本癌学会学術総会コアシンポジウム講演
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01027
  • [Presentation] 獲得免疫の驚くべき幸運2019

    • Author(s)
      本庶 佑
    • Organizer
      第52回日本薬剤師会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01027
  • [Presentation] DNAトポイソメラーゼ1は免疫グロブリン遺伝子組換え(多様化)に際してAIDに制御されDNA切断に働く2019

    • Author(s)
      小林 牧、本庶 佑
    • Organizer
      第42回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01027
  • [Presentation] Serendipities of acquired immunity2019

    • Author(s)
      Tasuku Honjo
    • Organizer
      IUIS 2019 (17th International Conference of Immunology)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01027
  • [Presentation] Histone Acetyl Reader BRD2 promotes AID–induced Genomic Instability.2018

    • Author(s)
      Santosh Kumar Gothwal, Nasim Begum and Tasuku Honjo.
    • Organizer
      2nd International Symposium of Radiation Therapeutics and Biology, Kyoto, Japan.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] Apurinic/apyrimidinic endonuclease 1 (APE1) is dispensable for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation in the immunoglobulin gene.2018

    • Author(s)
      Helena Islam, Maki Kobayashi and Tasuku Honjo.
    • Organizer
      2nd International Symposium of Radiation Therapeutics and Biology, Kyoto, Japan.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] IgH遺伝子多様化におけるノンコーディング germline transcriptの機能。2018

    • Author(s)
      小林 牧、本庶 佑。
    • Organizer
      第41回日本分子生物学会年会、横浜
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] RNA-binding motifs of AID cofactor hnRNP K are necessary for inducing DNA breaks in IgH locus.2018

    • Author(s)
      Ziwei Yin, Maki Kobayashi, Wenjun Hu, Nasim A. Begum, Tasuku Honjo.
    • Organizer
      The Keystone Symposia meeting on B Cells: Mechanisms in Immunity and Autoimmunity, 2018. Dresden, Germany.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] hnRNP KのRNA結合モチーフはAIDによる免疫グロブリン遺伝子多様化に必須である。2018

    • Author(s)
      Ziwei Yin, Maki Kobayashi, Wenjun Hu, Nasim A. Begum, Tasuku Honjo.
    • Organizer
      第41回日本分子生物学会年会、横浜
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] Function of Sμ-germline transcripts in activation-induced cytidine deaminase (AID)-induced DNA breaks.2018

    • Author(s)
      Maki Kobayashi, Misao Takemoto, Nasim A. Begum and Tasuku Honjo.
    • Organizer
      The Keystone Symposia meeting on B Cells: Mechanisms in Immunity and Autoimmunity, 2018. Dresden, Germany.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] Serendipities of acquired immunity2017

    • Author(s)
      Tasuku Honjo
    • Organizer
      Kyoto Prize Symposium in Oxford
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] Serendipities of acquired immunity2017

    • Author(s)
      Tasuku Honjo
    • Organizer
      IASLC 18th World Conference on Lung Cancer (WCLC 2017)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] Apurinic/Apyrimidinic endonuclease 1 (APE1)'s enrollment in activation induced cytidine deaminase (AID)-dependent IgH gene diversification2017

    • Author(s)
      Helena Islam、Maki Kobayashi、Tasuku Honjo
    • Organizer
      生命科学系学会合同年次大会 Conbio2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] Topoisomerase 1 enrolls in diversification of Ig gene under the regulation of activation-induced cytidine deaminase (AID).2017

    • Author(s)
      Kobayashi, M and Honjo, T.
    • Organizer
      International Symposium on Immune Diversity and Cancer Therapy Kobe 2017.
    • Place of Presentation
      神戸ポートピアホテル
    • Year and Date
      2017-01-26
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] Amazing Power of the Immune System2017

    • Author(s)
      Tasuku Honjo
    • Organizer
      2017年度生命科学系学会合同年次大会(ConBio2017)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] クラススイッチ組換えにおけるメチルトランスフェラーゼFBLの役割2017

    • Author(s)
      森脇 隆仁、Afzal Husain、小林 牧、本庶 佑
    • Organizer
      生命科学系学会合同年次大会 Conbio2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] Chromatin remodeler SMARCA4 recruits topoisomerase 1 and suppresses transcription associated genomic instability.2017

    • Author(s)
      Husain A., Honjo, T.
    • Organizer
      International Symposium on Immune Diversity and Cancer Therapy Kobe 2017.
    • Place of Presentation
      神戸ポートピアホテル
    • Year and Date
      2017-01-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] 獲得免疫が寿命を決める2017

    • Author(s)
      本庶 佑
    • Organizer
      第41回日本頭頸部癌学会 特別講演
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] Serendipities of acquired immunity2017

    • Author(s)
      Tasuku Honjo
    • Organizer
      Kyoto Prize Symposium in San Diego
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] 獲得免疫の驚くべき幸運2016

    • Author(s)
      本庶 佑
    • Organizer
      京都賞記念講演会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2016-11-11
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] Activation-induced cytidine deaminase (AID) diversifies immunoglobulin gene by regulating topoisomerase 1 (Top1).2016

    • Author(s)
      Kobayashi, M and Honjo, T.
    • Organizer
      分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-11-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] 獲得免疫の驚くべき幸運2016

    • Author(s)
      本庶 佑
    • Organizer
      京都賞記念鹿児島講演会
    • Place of Presentation
      鹿児島市民文化ホール
    • Year and Date
      2016-11-16
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] トポイソメラーゼⅠを介したAIDによる免疫グロブリン遺伝子の多様化2015

    • Author(s)
      小林 牧、本庶 佑
    • Organizer
      第17回 RNA meeting
    • Place of Presentation
      札幌パークホテル
    • Year and Date
      2015-07-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] Antibody Maturation and Class Switch2015

    • Author(s)
      本庶佑
    • Organizer
      Keystone Symposia on HIV Vaccines/The Golden Anniversary of B Cells "Antibody Maturation and Class Switch" session(Chair person /Symposium speaker)
    • Place of Presentation
      Banff, Canada
    • Year and Date
      2015-03-25
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] Immunoglobulin gene diversification by activation-Induced cytidine deaminase 8AID) through Topoisimerase1(Top1).2015

    • Author(s)
      Maki Kobayashi, Hiroyuki Wakaguri, Masakazu Shimizu, Koh-ichiro Higasa, Fumihiko Matsuda and Tasuku Honjo
    • Organizer
      The 2nd IFOM-Kyoto Univerity Joint Symposium
    • Place of Presentation
      京都大学芝蘭会館
    • Year and Date
      2015-10-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] トポイソメラーゼ1を介したAIDによる免疫グロブリン遺伝子の多様化2015

    • Author(s)
      小林 牧、本庶 佑
    • Organizer
      第17回 RNA meeting
    • Place of Presentation
      札幌パークホテル
    • Year and Date
      2015-07-15
    • Data Source
      KAKENHI-PROJECT-15H05784
  • [Presentation] Acetylated Histone Reader Brd4 Functions as a Repair Adaptor in Immunoglobulin Class Switch Recombination2014

    • Author(s)
      本庶佑
    • Organizer
      2014 Genomic Instability Gordon Research Conference(Symposium speaker)
    • Place of Presentation
      Hong Kong
    • Year and Date
      2014-07-09
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] AID's function in DNA cleavage and recombination of the immunoglobulin gene2014

    • Author(s)
      本庶佑
    • Organizer
      “Frontiers in immunology - from molecules to disease” at Nobel Forum(Symposium speaker)
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2014-06-13
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] Common features in the immune diversification and genome instability2013

    • Author(s)
      本庶 佑
    • Organizer
      The joint conference of Human Genome Meeting 2003 and 21st International Congress of Genetics
    • Place of Presentation
      Singapore
    • Year and Date
      2013-04-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] Molecular mechanism for antibody memory generation2013

    • Author(s)
      本庶 佑
    • Organizer
      15th ICI Milan 2013
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2013-08-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] Non canonical function of UNG regulates AID-dependent antibody memory2013

    • Author(s)
      本庶 佑
    • Organizer
      Charles A. Janeway Jr. Memorial Symposium
    • Place of Presentation
      New Haven, USA
    • Year and Date
      2013-06-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] Common mechanisms for immune diversity and genome instability2012

    • Author(s)
      本庶佑
    • Organizer
      The 2012 Gordon Research Conference on DNA Damage, Mutation and Cancer
    • Place of Presentation
      California, USA
    • Year and Date
      2012-03-27
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] An evolutionary view of the mechanism for immune and genome diversity2012

    • Author(s)
      本庶佑
    • Organizer
      Keystone Symposia : Mutation, Malignancy and Memory-Antibodies and Immunity
    • Place of Presentation
      Boston, USA
    • Year and Date
      2012-03-19
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] RNA editing hypothesis for antibody memory generation2011

    • Author(s)
      本庶佑
    • Organizer
      The 2011 Gordon Research Conference on RNA Editing
    • Place of Presentation
      Texas, USA
    • Year and Date
      2011-01-10
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] Dilemma of AID : infection or cancer2011

    • Author(s)
      本庶佑
    • Organizer
      The 2011 Spring Conference of the Korean Association of Immunologists
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2011-06-04
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] Dilemma of AID : infection or cancer2011

    • Author(s)
      本庶佑
    • Organizer
      JSPSフォーラム2011
    • Place of Presentation
      Washington, D.C., USA
    • Year and Date
      2011-06-21
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] Dilemma of AID : infection or cancer2011

    • Author(s)
      本庶佑
    • Organizer
      Bob Smith Lecture at MD Anderson Cancer Center
    • Place of Presentation
      Texas, USA
    • Year and Date
      2011-01-12
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] Dilemma of AID : immunity or tumor2011

    • Author(s)
      本庶佑
    • Organizer
      Qilu International Conference on Infection and Immunity & 2nd CMI Symposium on Immunology
    • Place of Presentation
      Jinan, China
    • Year and Date
      2011-10-11
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] Common properties between class switch and meiotic homologous recombination.2010

    • Author(s)
      本庶佑
    • Organizer
      Cold Spring Harbor Laboratory Meeting on "Gene Expression and Signaling in the Immune System"
    • Place of Presentation
      New York, USA
    • Year and Date
      2010-04-24
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] Common properties between class switch and meiotic homologous recombination2010

    • Author(s)
      本庶佑
    • Organizer
      Cold Spring Harbor Laboratory Meeting on "Gene Expression and Signaling in the Immune System"
    • Place of Presentation
      New York, USA
    • Year and Date
      2010-04-24
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] Epigenetic regulation of S region chromatin is essential to AID-induced S region DNA cleavage by topoisomerase 12010

    • Author(s)
      本庶佑
    • Organizer
      International AID workshop : From Immune Diversification to Cancer, a Marcus Wallenberg Symposium
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2010-06-03
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] Evolutional origin of class switch recombination2010

    • Author(s)
      本庶佑
    • Organizer
      The 14th International Congress of Immunology (ICI2010)
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2010-08-25
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] Conserved mechanism for immune and genomic diversit2010

    • Author(s)
      本庶佑
    • Organizer
      Symposium des Treilles "Break down of tolerance to self : from innate immunity to auto-immune diseases"
    • Place of Presentation
      Draguignan, France
    • Year and Date
      2010-07-27
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] AID-mediated antibody memory generation and genomic instability2010

    • Author(s)
      本庶佑
    • Organizer
      The 18th Symposium on Recent Advances in Cellular and Molecular Biology細胞及び分子生物学学会
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2010-01-21
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] Epigenetic regulation of S region chromatin is essential to AID-induced Sregion DNA cleavage by topoisomerase 12010

    • Author(s)
      本庶佑
    • Organizer
      International AID workshop : From Immune Diversification to Cancer, a Marcus Wallenberg Symposium
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2010-06-03
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] Knock-in mice carrying a somatic hypermutation-defective Aicda mutation have impaired gut homeostasis and compromised mucosal defense2010

    • Author(s)
      本庶佑
    • Organizer
      The 4th International Conference on "B cells and Autoimmunity" (BCAI 2010)
    • Place of Presentation
      Nara, Japan
    • Year and Date
      2010-08-20
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] Conserved mechanism for immune and genomic diversit2010

    • Author(s)
      本庶佑
    • Organizer
      Symposium des Treilles "Break down of tolerance to self : from innate immunity to auto-immune diseases"
    • Place of Presentation
      Draguignan, France
    • Year and Date
      2010-07-27
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] Evolutional origin of class switch recombination2010

    • Author(s)
      本庶佑
    • Organizer
      The 14th International Congress of Immunology (ICI2010)
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2010-08-25
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] Role of AID in vaccination2010

    • Author(s)
      本庶佑
    • Organizer
      The 3rd International Symposium : Regulators and Adaptive Immunity
    • Place of Presentation
      Erlangen, German
    • Year and Date
      2010-10-15
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] Common properties between class switch and meiotic homologous recombination2010

    • Author(s)
      本庶佑
    • Organizer
      Cold Spring Harbor Laboratory Meeting on "Gene Expression and Signaling in the Immune System"
    • Place of Presentation
      New York, USA
    • Year and Date
      2010-04-24
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] Role of AID in vaccination2010

    • Author(s)
      本庶佑
    • Organizer
      The 3rd International Symposium : Regulators and Adaptive Immunity
    • Place of Presentation
      Erlangen, German
    • Year and Date
      2010-10-15
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] Knock-in mice carrying a somatic hypermutation-defective Aicda mutation have impaired gut homeostasis and compromised mucosal defense2010

    • Author(s)
      本庶佑
    • Organizer
      The 4th International Conference on "B cells and Autoimmunity" (BCAI 2010)
    • Place of Presentation
      Nara, Japan
    • Year and Date
      2010-08-20
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] Molecular studies on generation of antibody memory2009

    • Author(s)
      本庶佑
    • Organizer
      The International Symposium on Genomics and Medicine, The Fondation Jean Dausset-Centre d'Etude du Polymorphisme Humain (CEPH)
    • Place of Presentation
      Paris, France
    • Year and Date
      2009-03-23
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] 抗体記憶をゲノムに刻むAID2009

    • Author(s)
      本庶佑
    • Organizer
      第59回日本アレルギー学会
    • Place of Presentation
      Akita, Japan
    • Year and Date
      2009-10-31
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] The molecular mechanism for generation of antibody memory2009

    • Author(s)
      本庶佑
    • Organizer
      The 2009 Keystone Symposium on Human Immunology and Immunodeficiencies
    • Place of Presentation
      Beijing, China
    • Year and Date
      2009-05-13
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] Involvement of topoisomerase 1 in AID-mediated antibody memory generation and genomic instability2009

    • Author(s)
      本庶佑
    • Organizer
      The Annual Meeting of the Korean Society for Molecular and Cellular Biology
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2009-10-15
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] ワクチンによる抗体記憶形成のメカニズム、またはMolecular mechanism of generation of antibody memory by vaccination2009

    • Author(s)
      本庶佑
    • Organizer
      日本消化器病学会
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2009-10-16
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] AID as the engraver of antibody memory and inducer of genome instability2009

    • Author(s)
      本庶佑
    • Organizer
      The First International Kishimoto Foundation Symposium : "Immune Regulation : Present and Future"
    • Place of Presentation
      Osaka, Japan
    • Year and Date
      2009-05-25
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] Molecular studies on generation of antibody memory.2009

    • Author(s)
      本庶佑
    • Organizer
      The International Symposium on Genomics and Medicine, The Fondation Jean Dausset-Centre d'Etude du Polymorphisme Humain (CEPH)
    • Place of Presentation
      Paris, France
    • Year and Date
      2009-03-23
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination.2009

    • Author(s)
      本庶佑
    • Organizer
      Seminar at NIMR, MRC
    • Place of Presentation
      London, UK
    • Year and Date
      2009-12-03
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] Dissociation of in vitro DNA deamination activity and physiological functions by AID mutants2008

    • Author(s)
      本庶佑
    • Organizer
      Workshop on AUD Biology and Disease
    • Place of Presentation
      North Carolina, USA
    • Year and Date
      2008-09-23
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] Molecular mechanism for generation of antibody memory2008

    • Author(s)
      本庶 佑
    • Organizer
      第38回日本免疫学会学術集会
    • Place of Presentation
      京都、日本
    • Year and Date
      2008-12-01
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] Molecular mechanism for generation of antibody memory2008

    • Author(s)
      本庶佑
    • Organizer
      2008 Leskowitz Memorial Lecture at Tufts University School of Medicine
    • Place of Presentation
      Boston, USA
    • Year and Date
      2008-09-26
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] The role of PD-1/PD-L in the pathogenesis of nephritis of NZB/W F1 mice2008

    • Author(s)
      Kasagi S, Kawano S, Morinobu A, Tanaka Y, Okazaki T, Minato N, Honjo T, and Kumagai S
    • Organizer
      第11回京都免疫ワークショップ
    • Place of Presentation
      京都
    • Year and Date
      2008-03-22
    • Data Source
      KAKENHI-PROJECT-19591167
  • [Presentation] Molecular mechanism for generation of antibody memory2008

    • Author(s)
      本庶佑
    • Organizer
      FIMSA 2008
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2008-10-17
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] Involvement of IFN-g producing CD4+PD-1+ T cells in lupus-prone NZB/W F1 mice2008

    • Author(s)
      Kasagi S, Kawano S, Morinobu A, Hatachi S, Simatani K, Tanaka Y, Minato N, Okazaki T, Honjo T, and Kumagai S
    • Organizer
      American College of Rheumatology, Annual Scientific Meeting
    • Place of Presentation
      at San Francisco
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-19591167
  • [Presentation] Molecular mechanism for generation of antibody memory.2008

    • Author(s)
      本庶佑
    • Organizer
      2008 Leskowitz Memorial Lecture at Tufts University School of Medicine
    • Place of Presentation
      Boston, USA
    • Year and Date
      2008-09-24
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation]2008

    • Author(s)
      Kasagi S, Kawano S, Morinobu A, Hatachi S, Okazaki T, Tanaka Y, Minato N, Honjo T, and Kumagai S
    • Organizer
      Kasagi S, Kawano S, Morinobu A, Hatachi S, Okazaki T, Tanaka Y, Minato N, Honjo T, and Kumagai S
    • Place of Presentation
      京都
    • Year and Date
      2008-12-03
    • Data Source
      KAKENHI-PROJECT-19591167
  • [Presentation] AID, the engraver of antibody memory2008

    • Author(s)
      本庶佑
    • Organizer
      Seminar at Seoul National University
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2008-07-18
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] Molecular mechanism for generation of antibody memory2008

    • Author(s)
      本庶佑
    • Organizer
      第38回日本免疫学会学術集会
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2008-12-01
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] ゲノムに刻む抗体記憶/AID, the engraver of antibody m2008

    • Author(s)
      本庶 佑
    • Organizer
      Japan-German Immunology Seminar 2008 : Immune Regulation in Health and Disease
    • Place of Presentation
      福岡、日本
    • Year and Date
      2008-11-03
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] Somatic hypermutation and class switch recombination2008

    • Author(s)
      本庶佑
    • Organizer
      The International Ataxia-Telangiectasia Workshop 2008
    • Place of Presentation
      Shiga, Japan
    • Year and Date
      2008-04-26
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] Dissociation of in vitro DNA deamination activity and physiological functions by AID mutants2008

    • Author(s)
      本庶佑
    • Organizer
      The Royal Society Discussion Meeting on DNA deamination in immunity, virology, and cancer
    • Place of Presentation
      London, UK
    • Year and Date
      2008-06-09
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] ゲノムに刻む抗体記憶/AID, the engraver of antibody memory2008

    • Author(s)
      本庶佑
    • Organizer
      Japan-German Immunology Seminar 2008 : Immune Regulation in Health and Disease
    • Place of Presentation
      Fukuoka, Japan
    • Year and Date
      2008-11-04
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] Molecular mechanism for antibody memory.The Heidelberger-Kabat Lecture2007

    • Author(s)
      本庶佑
    • Organizer
      the Dean's Lecture Series 2006-2007, Columbia University Medical Center
    • Place of Presentation
      New York, USA
    • Year and Date
      2007-02-15
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] Expression of PD-1/PD-L1 in the development of lupus-like nephritis in NZB/W F1 mice2007

    • Author(s)
      Kasagi S, Kawano S, Morinobu A, Hatachi S, Tanaka Y, Okazaki T, Minato N, Honjo T, and Kumagai S
    • Organizer
      第37回日本免疫学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-20
    • Data Source
      KAKENHI-PROJECT-19591167
  • [Presentation] AID for generation of antigen-induced immune diversity.2006

    • Author(s)
      本庶佑
    • Organizer
      Paul E. Lacy Lecturer at Washington University in St. Louis
    • Place of Presentation
      Louis, USA
    • Year and Date
      2006-05-01
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] AID, a central molecule of immune diversity.2005

    • Author(s)
      本庶佑
    • Organizer
      日独免疫セミナー
    • Place of Presentation
      Potsdam, Germany
    • Year and Date
      2005-09-18
    • Data Source
      KAKENHI-PROJECT-17002015
  • [Presentation] Acquired immunity, genome instability, cancer

    • Author(s)
      本庶 佑
    • Organizer
      Robert Koch Lecture
    • Place of Presentation
      Berlin, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] Evolution of immune diversity from genome instability

    • Author(s)
      本庶 佑
    • Organizer
      2012 French-Japanese Meeting "Immune Defenses in Humans and in Model Organisms"
    • Place of Presentation
      Tokyo, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] An evolutionary view of the mechanism for immune and genome diversity

    • Author(s)
      本庶 佑
    • Organizer
      Max-Planck Institute of Immunobiology and Epigenetics Special Guest Series
    • Place of Presentation
      Freiburg, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-22000015
  • [Presentation] Acquired immunity, genome instability, and cancer

    • Author(s)
      本庶 佑
    • Organizer
      Keystone Symposia: B Cell Development and Function
    • Place of Presentation
      Colorado, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-22000015
  • 1.  SASAZUKI Takehiko (50014121)
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  • 121.  嶋田 一夫 (70196476)
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  • 122.  堀之内 末治 (80143410)
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  • 123.  志村 令郎 (60025426)
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  • 124.  鎌田 博 (00169608)
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  • 125.  山田 康之 (50026415)
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  • 126.  軽部 征夫 (50089827)
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  • 127.  別府 輝彦 (80011873)
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  • 128.  斉藤 隆 (50205655)
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  • 129.  白井 俊一 (30115860)
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  • 130.  翠川 裕 (10209819)
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  • 131.  堤 寛 (80138643)
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  • 132.  金田 良雅 (60051471)
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  • 133.  長田 重一 (70114428)
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  • 134.  帯刀 益夫 (10099971)
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  • 135.  郡司 俊秋 (80250207)
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  • 136.  大江 和彦 (40221121)
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  • 137.  平井 百樹 (60156635)
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  • 138.  木村 賛 (20161565)
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  • 139.  DAVIS M.
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  • 140.  REINHARZ E.
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  • 141.  KIYONO H.
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  • 142.  LOH D.
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  • 143.  MARCHIANO Grazia
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  • 144.  MIYAWAKI Shigeki
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  • 145.  ISHIDA Hiroshi
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  • 146.  SHIBAYAMA Shiro
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  • 147.  FUKUSHIMA Daikichi
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  • 148.  COHN Melvin
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  • 149.  NUSSENZWEIK Ruth
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  • 150.  Nasim Begam A.
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  • 151.  Iwata So
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  • 152.  セベリンソン エバ
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  • 153.  SEVERINSON Eva
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  • 154.  エバ セベリンソン
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  • 155.  LIONELLO F.P
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  • 156.  ELENA BUSI
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  • 157.  BUSI Elena
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    # of Collaborated Products: 0 results
  • 158.  MRCHIANO Grazia
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    # of Collaborated Products: 0 results
  • 159.  PUNZO Lionello F.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 160.  SANDRO Brioc
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  • 161.  KINCADE Paul
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    # of Collaborated Products: 0 results
  • 162.  BALTIMORE Da
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  • 163.  SERCARZ Eli
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  • 164.  MCDEVITT Hug
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  • 165.  PAUL W. Kincade
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  • 166.  DAVID Baltimore
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  • 167.  ELI Sercarz
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  • 168.  HUGH O. McDevitt
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  • 169.  FRANCO Punzo
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  • 170.  PUNZO Lionello farnco
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  • 171.  LIONELLO Fra
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  • 172.  MATHIS D.
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  • 173.  BENOIST C
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  • 174.  PIATIGORSKY ジェイ
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  • 175.  MARTY J.L.
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  • 176.  THOMPSON C.
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  • 177.  GOSSLER A
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  • 178.  VAN Snick J.
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  • 179.  MITCHISON N.
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  • 180.  BORNKAMM G.W
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  • 181.  CHEIN K.R.
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  • 182.  HERZENBERG L
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  • 183.  LOOARESSUWAN ソンチャイ
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  • 184.  LOOAREESUWAN Sorchai
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  • 185.  LOOAREESUWAN ソンチャイ
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    # of Collaborated Products: 0 results
  • 186.  PONGPONRATN イー
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    # of Collaborated Products: 0 results
  • 187.  LOOARESUWAN エス
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  • 188.  CHEONGSUPHA ティー
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  • 189.  NUSSENZWEIG アール
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  • 190.  CONSTANTIN A. Bona
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    # of Collaborated Products: 0 results
  • 191.  CONSTANTIN A
    # of Collaborated Projects: 1 results
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  • 192.  CHOWDHURY PARTHA
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    # of Collaborated Products: 2 results
  • 193.  LEONG MAN LONG
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  • 194.  廣田 耕志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 195.  新蔵 礼子
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    # of Collaborated Products: 10 results
  • 196.  王 継揚
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    # of Collaborated Products: 1 results
  • 197.  森屋 恭爾
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 198.  小池 和彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 199.  竹馬 俊介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 200.  黒川 顕
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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