Koseki Haruhiko 古関明彦

… Alternative Names

KOSEKI Haruhiko 古関明彦

古関明彦コセキハルヒコ

Less

Researcher Number	40225446
Other IDs
External Links
Affiliation (Current)	2022: 国立研究開発法人理化学研究所, 生命医科学研究センター, チームリーダー 2022: 千葉大学, 大学院医学研究院, 教授
Affiliation (based on the past Project Information) *help	2017 – 2022: 国立研究開発法人理化学研究所, 生命医科学研究センター, チームリーダー 2017: 国立研究開発法人理化学研究所, その他, 研究員 2015 – 2017: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, グループディレクター 2015: 国立研究開発法人理化学研究所, その他部局等, その他 2014: 独立行政法人理化学研究所, その他部局等, その他 … More 2014: 理化学研究所・統合生命医科学研究センター, 免疫器官形成研究グループ, グループディレクター 2013 – 2014: 独立行政法人理化学研究所, 統合生命医科学研究センター, グループディレクター 2004 – 2012: 独立行政法人理化学研究所, 免疫器官形成研究グループ, グループディレクター 2011: 独立行政法人理化学研究所, 免疫器官形成研究グループ, グループリーダー 2010: 理化学研究所, 免疫器官形成研究グループ, グループディレクター 2010: 理化学研究所, 免疫器官形成研究グループ・グループディレクター 2006: Niigata University, Graduate School of Medical and Dental Sciences, Professor, 免疫器官形成研究グループ, グループデイレクター 2001 – 2004: Chiba Univeiisity, Graduate School of Medicine, Molecular Embryology, professor, 大学院・医学研究院, 教授 2003: 千葉大学, 大学院・医学研究部, 教授 2002: 千葉大学, 大学院・医学研究科・発生生物学部門, 教授 1998 – 2000: 千葉大学, 大学院・医学研究科, 教授 1999: 千葉大学, 医学部, 教授 1997: 千葉大学, 医学部, 助教授 1996: Chiba University, School of Medicine, Assist. 1994 – 1996: 千葉大学, 医学部, 助手 1995: 千葉大学, 医科部, 助手 1991: 千葉大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / General medical chemistry / General anatomy (including Histology/Embryology) / Experimental pathology / General medical chemistry Except Principal Investigator Biological Sciences / Hematology / Developmental biology / Neuroscience in general / Pediatric surgery … More / Human genetics / Stem cell biology and medical science / Developmental biology / Genome biology / Immunology / Ophthalmology / Anesthesiology/Resuscitation studies / Cell biology / Pathological medical chemistry / Biomedical engineering/Biological material science / Laboratory animal science Less
Keywords	Principal Investigator ポリコーム群 / クロマチン / Hox / マウス / スプライセオソーム / Mel18 / Bmi1 / 哺乳類 / ポリコム群 / mel-18 … More / bmi-1 / ホメオボックス / Mph2 / Ring1 / CpGアイランド / 脊索 / 細胞死 / ノックアウトマウス / ヒストン / PRC1 / PRC2 / Pax-1 / p53 / Polycomb / Rnf2 / Edr1 / 脊椎形成 / ウズラPax-1 / スクレロトーム分化 / モノクローナル抗体 / ポリコ-ム遺伝子 / 欠失マウス / ホメオテイック変異 / IL-7 / リンパ球前駆細胞増殖 / 前後軸形成 / 細胞死抑制 / MPH2 / 尾芽 / Th2 / FKH6 / 腸管付随リンパ組織 / パイエル板 / リンホトキシン / Fkh6 / 胃 / 間充織 / 精子形成 / 減数分裂 / ヘテロクロマチン / セントロメア / ヒストン修飾 / 対合 / Epc1 / Tip60 / ヒストンアセチル化 / HP1γ / 精母細胞 / 性染色体不活性化 / エピジェネティック制御 / ヘテロクロマチ / HP1_γ / ヘテロクロマチンタンパク-1(HP1γ) / ES細胞 / 転写制御 / Oct3 / 4 / ユビキチン / CpG配列 / エピジェネティクス / CXXCモチーフ / SRAドメイン / Cxxc5 / Np95/UHRF1 / 脊椎骨 / 腹背軸 / 硬節 / 体節分化 / コラーゲン(α1) / vertebral column / dorsovental axis / sclerotome / notochord / ノックアウト / 細胞老化 / 翻訳制御 / Pcl2 / Ink4a / 胎児性繊維芽細胞 / Ring1B / X染色体 / ヒストンH2A / ユビキチン化 / MBLR / E2F6複合体 / ホメオプロテインインターラクティングキナーゼ / プログラム細胞死 / Mel-18 / 細胞死制御 / knockout / cellular senescence / translational regulation / Pc12 / Cbx2 / Edr2 / ヒストンH3 / Topors / DNAダメージ / Mouse / Histon H3 / DNMT1 / ポリコム群遺伝子 / NP95/UHRF1 / RNF20 / ゲノム / 発現制御 / 遺伝子発現 / 複製フォーク / クロマチン複製 / DNA複製 / DNAメチル化 … More Except Principal Investigator ポリコーム群 / クロマチン / 分子シャペロン / 転写因子 / Hox / ノックアウトマウス / ポリコーム / ヒストン修飾 / エピジェネティクス / 小胞体 / スプライセオソーム / Mel-18 / 幹細胞 / ES細胞 / 転写制御 / 分化 / 転写抑制 / 骨髄異形成症候群 / マウスモデル / 遺伝子変異 / NMR / Biosensor / SLE / AGM / HSP27 / VP22 / KDEL receptor / COPI / HPV / E6 / Rlp7p / PTFE / 腫瘍内T細胞レパトア / PCR / T細胞抗原受容体 / TCRV領域 / 蛋白質品質管理機構 / KDEL レセプター / COPI 小胞 / BCL6 / BAZF / トランスジェニックマウス / IL-5 / アポトーシス / 科学研究費補助金特定領域(B) / 企画・調査 / 分節パターン / 会議開催 / 情報収集 / 造血幹細胞 / c-fos / AP-1 / マクロファージ / NF-IL-6 / Mel18 / Bmi1 / DES / Th2分化 / 核マトリクス / リンパ球 / Th2細胞 / Ring1B / 核マトリックス / ホメオボックス / 染色体免疫沈降 / 発がん / 細胞死制御 / p53 / データベース / cDNA / 抗体 / 扁桃体 / 海馬 / 情動 / 微小管 / アミノ酸配列 / huntingtin / プログラム細胞死 / 肝細胞 / マイクロアレイ / 子宮内胎児移植 / 幹細胞移植 / 未分化 / ヒストン / ユビキチンライゲース / XY体 / パキテン期 / ポリコム群複合体 / メチル化ヒストンH3K9 / Scmh1 / ポリコム群 / SUMO / ゲノム刷り込み / 刷り込みドメイン / non-coding RNA / siRNAライブラリー / KIP2 / LIT1刷り込みドメイン / 転写 / 発生 / 胚性幹細胞 / 初期発生 / 細胞分化 / ユビキチン化ヒストンH2A / 神経幹細胞 / 大脳皮質発生 / 多分化能 / バイオテクノロジー / 部位特異的組み換え / 病態モデル動物 / 有用遺伝子探索 / 染色体工学 / 遺伝子改変動物 / ゲノム編集 / ゲノム操作技術 / 遺伝子 / 動物 / 機能ゲノム / 発生・分化 / 病態モデルマウス / ゲノム / 血液内科学 / 血液腫瘍学 / 二次性白血病 / スプライシング因子 / コヘシン / クローン進化 / ゲノムシーケンス / 分裂酵母 / Cre-IoxP / 形態形成 / 高等植物 / 遺伝子標的 / 分子相互作用 / バイオセンサー / 免疫系 / 免疫病 / ATPase / 温度感受性突然変異体 / 細胞周期 / DNA再複製 / バイオモニタリング / RNAプロセシング / 遺伝子ターゲティング / 蛋白高次機能構造 / 胚形成 / 植物 / Fission yeast / Cre-loxP / Morphogenesis / Higher plants / Gene targeting / Protein interaction / 自己免疫病 / Vα14NKT細胞 / 胎生初期分化 / invariant TCR / 胸腺外T細胞分化 / Vα14T細胞 / 胸腺外分化 / 均一な抗原受容体 / 胎児肝 / 受容体遺伝子再構成 / Autoimmune disease / Valpha14 NK T cells / Invariant Valpha14 / Extrathymic development / 網膜色素上皮細胞移植 / 網膜変性症 / 拒絶反応 / 網膜色素上皮移植 / retinal pigment epithelium transplantation / retinitis pigmentosa / rejection / electrophysiology / T細胞 / 免疫寛容 / B細胞 / 発生工学 / ポリコ-ム遺伝子 / 水晶体特異的遺伝子発現 / 有機リン系農薬センサー / T cell / Immunological tolerance / B cell / Transgenics / Polycomb genes / Crystallin gene / Transcriptional factor / ストレス蛋白 / heat shock protein / 酸化ストレス / 細胞保護 / 分泌 / stress protein / molecular chaperone / ゴルジ体 / CopI / Golgi / ER / chaperone / 足場依存性 / リボゾーム関連タンパク質 / anchorage dependence / ribosome related protein / 骨髄細胞 / CD34陽性細胞 / 末梢血単核球細胞 / 細胞増殖因子 / 人工細胞外マトリックス / フィブロネクチン / 組織工学 / VEGF / Bone Marrow Cell / CD34 positive cells / Peripheral Blood MNC / Growth Factor / Artificial ECM / Fibronectin / Tissue Engineering / ミュータジェネシス / マウス / 逆遺伝学 / ゲノム機能 / 遺伝子機能 / 突然変異誘発 / エチルニトロソウレア / モデル動物 / 標的遺伝子変異体 / mutagenesis / mouse / reverse genetics / genome function / gene function / induced mutation / ethyl nitrosourea / 急性骨髄性白血病 / 遺伝子改変マウス / 新規遺伝子変異 / DDX41 Less

ポリコム群による抑制ドメインの複製機構の解明Principal Investigator
- Principal Investigator
  
  古関明彦
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Institute of Physical and Chemical Research
Towards understanding the role for DNMT1 to establish Polycomb-mediated gene silencingPrincipal Investigator
- Principal Investigator
  
  Koseki Haruhiko
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Institute of Physical and Chemical Research
Biological characterization of DDX41 germline and somatic mutations in myeloid neoplasms
- Principal Investigator
  
  Kon Ayana
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
Molecular pathogenesis in myelodysplastic syndromes (MDS).
- Principal Investigator
  
  OGAWA SEISHI
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
New site-specific recombination systems for genome engineering, VCre/VloxP and SCre/SloxP
- Principal Investigator
  
  NAKAYAMA MANABU
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Genome biology
- Research Institution
  Kazusa DNA Research Institute
The role of CpG dinucleotides to generate PcG-repressive genomic domainsPrincipal Investigator
- Principal Investigator
  
  KOSEKI HARUHIKO
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Institute of Physical and Chemical Research
Epigenetic regulation of embryonic and somatic stem cells by Polycomb
- Principal Investigator
  
  ENDOH Mitsuhiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Stem cell biology and medical science
- Research Institution
  The Institute of Physical and Chemical Research
Temporal regulation of cortical neural precursor cell fate by polycomb group proteins
- Principal Investigator
  
  HIRABAYASHI Yusuke
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  The University of Tokyo
Epigenetic regulation of mammalian spermatogenesisPrincipal Investigator
- Principal Investigator
  
  KOSEKI Haruhiko
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Dissecting molecular mechanisms mediated by Polycomb group proteins in maintenance and differentiation of ES cellsPrincipal Investigator
- Principal Investigator
  
  KOSEKI HARUHIKO
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  The Institute of Physical and Chemical Research
Identification of regulatory factors for genomic imprinting using siRNA library
- Principal Investigator
  
  SOEJIMA Hidenobu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  Saga University
XY体形成過程におけるほ乳類ポリコム群の機能発現メカニズムの解明
- Principal Investigator
  
  TAKADA Yuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
哺乳類ポリコーム群遺伝子によるES細胞の未分化性維持・分化の制御機構の解明
- Principal Investigator
  
  MITSUHIRO Endoh
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Development of mutant mice carrying base-substitutions in target genes.
- Principal Investigator
  
  GONDO Yoichi
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  RIKEN
哺乳類ポリコーム群による細胞増殖と細胞死制御の分子機序
- Principal Investigator
  
  青江知彦
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
幹細胞移植による子宮内胎児治療法の確立に関する研究
- Principal Investigator
  
  鈴木盛一
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pediatric surgery
- Research Institution
  National Research Institute for Child Health and Development
Association of mammalian PcG multimeric protein complexes to Hoxb8 genePrincipal Investigator
- Principal Investigator
  
  KOSEKI Haruhiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Chiba University
The analysis of a novel gene E6DG1 function involving in anchorage dependency
- Principal Investigator
  
  SHIRASAWA Hiroshi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Chiba University
Bone Marrow Cell Culture for Producing Tissue Engineered Regenerative Blood Vessels as a Goal of Clinical Application
- Principal Investigator
  
  ISHIDA Atsushi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Chiba University
哺乳類ポリコーム群によるリンパ球機能のコントロール
- Principal Investigator
  
  青江知彦
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
哺乳類ポリコーム群が構成する核内機能ドメインの作用発現機序の解析
- Principal Investigator
  
  磯野協一
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
哺乳類ポリコーム群による細胞増殖と細胞死制御の分子機序
- Principal Investigator
  
  青江知彦
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
ヒト脳内長鎖cDNA解析データベースを基盤としたマウス扁桃体の情動神経機構の解明
- Principal Investigator
  
  湯浅茂樹
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neuroscience in general
- Research Institution
  National Center of Neurology and Psychiatry
  Chiba University
Molecular mechanisms that integrate 'cell death and cell cycle progression.Principal Investigator
- Principal Investigator
  
  KOSEKI Haruhiko
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  RIKEN
  Chiba University
脳のパターン形成と細胞死抑制の課程における哺乳類ポリコーム群の機能発現機序Principal Investigator
- Principal Investigator
  
  古関明彦
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
ポリコーム遺伝子Mel-18とBim-1の前後軸形成における機能Principal Investigator
- Principal Investigator
  
  古関明彦
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Chiba University
AP-1遺伝子群による造血制御
- Principal Investigator
  
  岡田誠治
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
免疫細胞の分化と増殖における哺乳類ポリコーム群の機能発現機序Principal Investigator
- Principal Investigator
  
  古関明彦
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
ポリコーム群が構成する核内機能ドメインの機能発現機序Principal Investigator
- Principal Investigator
  
  古関明彦
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
哺乳類ポリコーム群による細胞増殖と細胞死制御機序の解明Principal Investigator
- Principal Investigator
  
  古関明彦
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
内分泌かく乱物質による晩発障害発生の分子メカニズムの解析
- Principal Investigator
  
  赤坂武
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Institution
  Chiba University
胃機能発現の分子メカニズムの解析Principal Investigator
- Principal Investigator
  
  古関明彦
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Chiba University
The KDEL receptor and vesicular traffic
- Principal Investigator
  
  AOE Tomohiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  CHIBA UNIVERSITY
ポリコーム群遺伝子Mel-18とBmi-1の前後軸形成における機能Principal Investigator
- Principal Investigator
  
  古関明彦
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Chiba University
小胞体分子シャペロンによる細胞内蛋白質輸送の制御
- Principal Investigator
  
  AOE Tomohiko
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Chiba University
転写抑制因子(BCL6遺伝子群とポリコーム遺伝子群)による造血制御
- Principal Investigator
  
  岡田誠治
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
脊椎動物の分節性の分枝基盤とその進化
- Principal Investigator
  
  高橋淑子
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  Nara Institute of Science and Technology
A new approach for cellular injury
- Principal Investigator
  
  AOE Tomohiko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Chiba University
脊椎動物・ポリコーム遺伝子産物による前後軸形成のコントロールPrincipal Investigator
- Principal Investigator
  
  古関明彦
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Chiba University
ポリコ-ム遺伝子Mel-18とBmi-1の前後軸形成における機能Principal Investigator
- Principal Investigator
  
  古関明彦
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
Regulation of Gene Expression
- Principal Investigator
  
  TANIGUCHI Masaru
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Chiba University, School of Medicine
Research of inhibition in rejection of retinal pigment epithelium transplantation
- Principal Investigator
  
  ADACHI Emiko
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Chiba University
Functional analysis of roles of Pax-1 during vertebral column developmentPrincipal Investigator
- Principal Investigator
  
  KOSEKI Haruhiko
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Chiba University, School of Medicine
脊椎形成を統御する転写活性化因子Pax-1遺伝子の発現調節機構Principal Investigator
- Principal Investigator
  
  古関明彦
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Chiba University
胸腺外T細胞初期分化
- Principal Investigator
  
  TANIGUCHI Masaru
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Chiba University School of Medicine
Regulation of Gene Expression
- Principal Investigator
  
  TANIGUCHI Masaru
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Chiba University
がんの免疫系からのエスケ-プ機構
- Principal Investigator
  
  TANIGUCHI Masaru
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Chiba University

[Book] ヒストンH2Aのユビキチン化による遺伝子発現の制御生体の科学60巻2009
- Author(s)
  遠藤充浩、古関明彦
- Data Source
  KAKENHI-PROJECT-21602006
[Journal Article] Bivalent-histone-marked immediate-early gene regulation is vital for VEGF-responsive angiogenesis.2022
- Author(s)
  Kanki Yasuharu、Muramatsu Masashi、Miyamura Yuri、Kikuchi Kenta、Higashijima Yoshiki、Nakaki Ryo、Suehiro Jun-ichi、Sasaki Yuji、Kubota Yoshiaki、Koseki Haruhiko、Morioka Hiroshi、Kodama Tatsuhiko、Nakao Mitsuyoshi、Kurotaki Daisuke、Aburatani Hiroyuki、Minami Takashi
- Journal Title
  
  Cell Rep.
  
  Volume: 38 Pages: 110332-110332
- DOI
  10.1016/j.celrep.2022.110332
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0026, KAKENHI-PLANNED-19H05744, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-19H01031, KAKENHI-PROJECT-20H03432, KAKENHI-PROJECT-21H02686, KAKENHI-PROJECT-21H02917, KAKENHI-PROJECT-20KK0185
[Journal Article] Insufficiency of non-canonical PRC1 synergizes with JAK2V617F in the development of myelofibrosis.2022
- Author(s)
  Shinoda Daisuke、Nakajima-Takagi Yaeko、Oshima Motohiko、Koide Shuhei、Aoyama Kazumasa、Saraya Atsunori、Harada Hironori、Rahmutulla Bahityar、Kaneda Atsushi、Yamaguchi Kiyoshi、Furukawa Yoichi、Koseki Haruhiko、Shimoda Kazuya、Tanaka Tomoaki、Sashida Goro、Iwama Atsushi
- Journal Title
  
  Leukemia
  
  Volume: 36 Pages: 452-463
- DOI
  10.1038/s41375-021-01402-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08824, KAKENHI-PROJECT-20K21625, KAKENHI-PROJECT-20K17370, KAKENHI-PLANNED-19H05745, KAKENHI-PLANNED-19H05746, KAKENHI-PROJECT-19H05653, KAKENHI-PROJECT-19H03708, KAKENHI-PROJECT-20H03713, KAKENHI-PROJECT-21K08366, KAKENHI-PROJECT-21K19398
[Journal Article] Establishment of mouse stem cells that can recapitulate the developmental potential of primitive endoderm2022
- Author(s)
  Ohinata Yasuhide、Endo Takaho A.、Sugishita Hiroki、Watanabe Takashi、Iizuka Yusuke、Kawamoto Yurie、Saraya Atsunori、Kumon Mami、Koseki Yoko、Kondo Takashi、Ohara Osamu、Koseki Haruhiko
- Journal Title
  
  Science
  
  Volume: 375 Pages: 574-578
- DOI
  10.1126/science.aay3325
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19H05745, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-20K20375
[Journal Article] Eosinophils: Cells known for over 140 years with broad and new functions2021
- Author(s)
  Kiuchi Masahiro、Onodera Atsushi、Kokubo Kota、Ichikawa Tomomi、Morimoto Yuki、Kawakami Eiryo、Takayama Naoya、Eto Koji、Koseki Haruhiko、Hirahara Kiyoshi、Nakayama Toshinori
- Journal Title
  
  J Exp Med.
  
  Volume: 218 Pages: 3-8
- DOI
  10.1084/jem.20201690
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-19K16683, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03685, KAKENHI-PROJECT-18K07164, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-21K20754
[Journal Article] Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing2021
- Author(s)
  Mochizuki K, Sharif J, Shirane K, Uranishi K, Bogutz AB, Janssen SM, Suzuki A, Okuda A, Koseki H, Lorincz MC.
- Journal Title
  
  Nature Communications
  
  Volume: 12(1) Pages: 7020-7020
- DOI
  10.1038/s41467-021-27345-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16147, KAKENHI-PROJECT-17KK0185, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-19H03426, KAKENHI-PROJECT-21K06843
[Journal Article] H2AK119ub1 guides maternal inheritance and zygotic deposition of H3K27me3 in mouse embryos2021
- Author(s)
  Mei Hailiang、Kozuka Chisayo、Hayashi Ryoya、Kumon Mami、Koseki Haruhiko、Inoue Azusa
- Journal Title
  
  Nature Genetics
  
  Volume: 53 Pages: 539-550
- DOI
  10.1038/s41588-021-00820-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05754, KAKENHI-PROJECT-18H02359, KAKENHI-PROJECT-20J21541, KAKENHI-PROJECT-19K17971, KAKENHI-PLANNED-19H05745, KAKENHI-ORGANIZER-19H05749
[Journal Article] MORC3, a novel MIWI2 association partner, as an epigenetic regulator of piRNA dependent transposon silencing in male germ cells2021
- Author(s)
  Kojima-Kita Kanako、Kuramochi-Miyagawa Satomi、Nakayama Manabu、Miyata Haruhiko、Jacobsen Steven E.、Ikawa Masahito、Koseki Haruhiko、Nakano Toru
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Pages: 20472-20490
- DOI
  10.1038/s41598-021-98940-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-19H03421, KAKENHI-PROJECT-19K16141
[Journal Article] UV-induced reduction in Polycomb repression promotes epidermal pigmentation2021
- Author(s)
  Li Meng-Yen、Flora Pooja、Pu Hong、Bar Carmit、Silva Jose、Cohen Idan、Galbo Phillip M.、Liu Hequn、Yu Xufen、Jin Jian、Koseki Haruhiko、D’Orazio John A.、Zheng Deyou、Ezhkova Elena
- Journal Title
  
  Developmental Cell
  
  Volume: 56
- DOI
  10.1016/j.devcel.2021.08.006
- Data Source
  KAKENHI-PLANNED-19H05745
[Journal Article] Staphylococcus cohnii is a potentially biotherapeutic skin commensal alleviating skin inflammation2021
- Author(s)
  Ito Y, Sasaki T, Li Y, et al
- Journal Title
  
  Cell Reports
  
  Volume: 35 Pages: 109052-109052
- DOI
  10.1016/j.celrep.2021.109052
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-20H05627, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-20H00495, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-21K08308
[Journal Article] Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes2021
- Author(s)
  Sugishita Hiroki、Kondo Takashi、Ito Shinsuke、Nakayama Manabu、Yakushiji-Kaminatsui Nayuta、Kawakami Eiryo、Koseki Yoko、Ohinata Yasuhide、Sharif Jafar、Harachi Mio、Blackledge Neil P.、Klose Robert J.、Koseki Haruhiko
- Journal Title
  
  Nature Communications
  
  Volume: 12 Pages: 5341-5341
- DOI
  10.1038/s41467-021-24894-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06621, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-21K09784, KAKENHI-PROJECT-20K20375
[Journal Article] Maintenance DNA methylation in pre-meiotic germ cells regulates meiotic prophase by facilitating homologous chromosome pairing2021
- Author(s)
  Takada Yuki、Yaman-Deveci Ruken、Shirakawa Takayuki、Sharif Jafar、Tomizawa Shin-ichi、Miura Fumihito、Ito Takashi、Ono Michio、Nakajima Kuniko、Koseki Yoko、Shiotani Fuyuko、Ishiguro Kei-ichiro、Ohbo Kazuyuki、Koseki Haruhiko
- Journal Title
  
  Development
  
  Volume: 148
- DOI
  10.1242/dev.194605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06642, KAKENHI-PUBLICLY-20H05370, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-19K07250, KAKENHI-PROJECT-19KK0183
[Journal Article] Tet DNA demethylase is required for plasma cell differentiation by controlling expression levels of IRF42020
- Author(s)
  Fujii, K. Tanaka, S. Hasegawa, T. Narazaki, M. Kumanogoh, A. Koseki, H. Kurosaki, T. Ise, W.
- Journal Title
  
  International Immunology
  
  Volume: 32 Pages: 683-690
- DOI
  10.1093/intimm/dxaa042
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08883, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-17K10002, KAKENHI-PROJECT-20H03503
[Journal Article] CDCA7 and HELLS suppress DNA:RNA hybrid-associated DNA damage at pericentromeric repeats2020
- Author(s)
  Unoki Motoko、Sharif Jafar、Saito Yuichiro、Velasco Guillaume、Francastel Claire、Koseki Haruhiko、Sasaki Hiroyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Pages: 17865-17865
- DOI
  10.1038/s41598-020-74636-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05740, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-18K06961
[Journal Article] Effects of BMP7 produced by group 2 innate lymphoid cells on adipogenesis2020
- Author(s)
  Miyajima Yurina、Ealey Kafi N、Motomura Yasutaka、Mochizuki Miho、Takeno Natsuki、Yanagita Motoko、Economides Aris N、Nakayama Manabu、Koseki Haruhiko、Moro Kazuyo
- Journal Title
  
  International Immunology
  
  Volume: 32 Pages: 407-419
- DOI
  10.1093/intimm/dxaa013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-16H02622
[Journal Article] DNA methylation-based classification reveals difference between pediatric T-cell acute lymphoblastic leukemia and normal thymocytes.2020
- Author(s)
  Shrestha R, Sakata-Yanagimoto M, Maie K, Oshima M, Ishihara M, Suehara Y, Fukumoto K,1 Nakajima-Takagi Y, Matsui H, Kato T, Muto H, Sakamoto T, Kusakabe M, Nannya Y, Makishima H, Ueno H, Saiki R, Ogawa S, Chiba K, Shiraishi Y, Miyano S, Mouly E, Bernard OA, Inaba T, Koseki H, Iwama A, Chiba S
- Journal Title
  
  Blood Advances
  
  Volume: 4(5) Pages: 845-854
- DOI
  10.1182/bloodadvances.2019001324
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08334, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-18H02838, KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-20K08725, KAKENHI-PROJECT-19K23879, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-16H02622
[Journal Article] Pivotal role of CD103 in the development of psoriasiform dermatitis2020
- Author(s)
  Fukui Takehito、Fukaya Tomohiro、Uto Tomofumi、Takagi Hideaki、Nasu Junta、Miyanaga Noriaki、Nishikawa Yotaro、Koseki Haruhiko、Choijookhuu Narantsog、Hishikawa Yoshitaka、Yamashita Yoshihiro、Sato Katsuaki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Pages: 1-11
- DOI
  10.1038/s41598-020-65355-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-18K15194, KAKENHI-PROJECT-19K16477
[Journal Article] The Polycomb group protein Ringl regulates dorsoventral patterning of the mouse telencephalon2020
- Author(s)
  Hikaru Eto, Yusuke Kishi, Nayuta Yakushiji-Kaminatsui, Hiroki Sugishita, Shun Utsunomiya, Haruhiko Koseki, Yukiko Gotoh
- Journal Title
  
  Nature Communications
  
  Volume: 11 Pages: 5709-5709
- DOI
  10.1038/s41467-020-19556-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H05253, KAKENHI-PLANNED-19H05745, KAKENHI-PUBLICLY-20H05383, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-20J14522, KAKENHI-PROJECT-19K22695, KAKENHI-PROJECT-18K14622, KAKENHI-PROJECT-16H06279, KAKENHI-PLANNED-16H06481
[Journal Article] Human gain-of-function STAT1 mutation disturbs IL-17 immunity in mice2020
- Author(s)
  Tamaura Moe、Satoh-Takayama Naoko、Tsumura Miyuki、Sasaki Takaharu、Goda Satoshi、Kageyama Tomoko、Hayakawa Seiichi、Kimura Shunsuke、Asano Takaki、Nakayama Manabu、Koseki Haruhiko、Ohara Osamu、Okada Satoshi、Ohno Hiroshi、Kobayashi Masao
- Journal Title
  
  International Immunology
  
  Volume: － Pages: 259-272
- DOI
  10.1093/intimm/dxz079
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0228, KAKENHI-PROJECT-19H03620, KAKENHI-PROJECT-17K10112, KAKENHI-PROJECT-20K08158, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-18K07189, KAKENHI-PROJECT-18K07847
[Journal Article] Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity.2020
- Author(s)
  Tanaka, S. Ise, W. Inoue, T. Ito, A. Ono, C. Shima, Y. Sakakibara, S. Nakayama, M. Fujii, K. Miura, I. Sharif, J. Koseki, H. Koni, P. A. Raman, I. Li, Q. Z. Kubo, M. Fujiki, K. Nakato, R. Shirahige, K. Araki, H. Miura, F. Ito, T. Kawakami, E. Baba, Y. Kurosaki, T.
- Journal Title
  
  Nat. Immunol.
  
  Volume: 21 Pages: 950-961
- DOI
  10.1038/s41590-020-0700-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08883, KAKENHI-PROJECT-20K21384, KAKENHI-PLANNED-17H06331, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-18H02626, KAKENHI-PROJECT-19H03491, KAKENHI-PROJECT-19K22537, KAKENHI-PROJECT-20H03503
[Journal Article] Deep phenotyping of myalgic encephalomyelitis/chronic fatigue syndrome in Japanese population2020
- Author(s)
  Toshimori K, Fukuda S, et al.
- Journal Title
  
  Sci. Rep.
  
  Volume: 10 Pages: 19933-19933
- DOI
  10.1038/s41598-020-77105-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11521, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-18H02724
[Journal Article] Phc2 controls hematopoietic stem and progenitor cell mobilization from bone marrow by repressing Vcam1 expression2019
- Author(s)
  Bae Joonbeom、Choi Sang-Pil、Isono Kyoichi、Lee Ji Yoon、Park Si-Won、Choi Chang-Yong、Han Jihye、Kim Sang-Hoon、Lee Han-Hyoung、Park Kyungmin、Jin Hyun Yong、Lee Suk Jun、Park Chung-Gyu、Koseki Haruhiko、Lee Young Sik、Chun Taehoon
- Journal Title
  
  Nature Communications
  
  Volume: 10
- DOI
  10.1038/s41467-019-11386-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-16H02622
[Journal Article] Chromatin and epigenetics in development: a Special Issue2019
- Author(s)
  Bruneau Benoit G.、Koseki Haruhiko、Strome Susan、Torres-Padilla Maria-Elena
- Journal Title
  
  Development
  
  Volume: 146 Pages: 185025-185025
- DOI
  10.1242/dev.185025
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05745
[Journal Article] PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation2019
- Author(s)
  Healy Evan、Mucha Marlena、Glancy Eleanor、Fitzpatrick Darren J.、Conway Eric、Neikes Hannah K.、Monger Craig、Van Mierlo Guido、Baltissen Marijke P.、Koseki Yoko、Vermeulen Michiel、Koseki Haruhiko、Bracken Adrian P.
- Journal Title
  
  Molecular Cell
  
  Volume: 76
- DOI
  10.1016/j.molcel.2019.08.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-16H02622
[Journal Article] Np95/Uhrf1 regulates tumor suppressor gene expression of neural stem/precursor cells, contributing to neurogenesis in the adult mouse brain2019
- Author(s)
  Murao Naoya、Matsubara Shuzo、Matsuda Taito、Noguchi Hirofumi、Mutoh Tetsuji、Mutoh Masahiro、Koseki Haruhiko、Namihira Masakazu、Nakashima Kinichi
- Journal Title
  
  Neuroscience Research
  
  Volume: in press Pages: 31-43
- DOI
  10.1016/j.neures.2018.05.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14820, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-17K15624
[Journal Article] KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity2019
- Author(s)
  Turberfield Anne H、Kondo Takashi、Nakayama Manabu、Koseki Yoko、King Hamish W、Koseki Haruhiko、Klose Robert J
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 47 Pages: 9005-9023
- DOI
  10.1093/nar/gkz607
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-16H02622
[Journal Article] DNMTs and SETDB1 function as co-repressors in MAX-mediated repression of germ cell-related genes in mouse embryonic stem cells.2019
- Author(s)
  Tatsumi Daiki、Hayashi Yohei、Endo Mai、Kobayashi Hisato、Yoshioka Takumi、Kiso Kohei、Kanno Shinichiro、Nakai Yuji、Maeda Ikuma、Mochizuki Kentaro、Tachibana Makoto、Koseki Haruhiko、Okuda Akihiko、Yasui Akira、Kono Tomohiro、Matsui Yasuhisa
- Journal Title
  
  PLoS One.
  
  Volume: 13
- DOI
  10.1371/journal.pone.0205969
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07726, KAKENHI-ORGANIZER-17H06423, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-16H05143, KAKENHI-PROJECT-18H02419, KAKENHI-PROJECT-15H05579, KAKENHI-PLANNED-17H06424, KAKENHI-PUBLICLY-18H04875
[Journal Article] Polycomb Repressive Complex 1 Controls Maintenance of Fungiform Papillae by Repressing Sonic Hedgehog Expression2019
- Author(s)
  Bar Carmit、Cohen Idan、Zhao Dejian、Pothula Venu、Litskevitch Anna、Koseki Haruhiko、Zheng Deyou、Ezhkova Elena
- Journal Title
  
  Cell Reports
  
  Volume: 28
- DOI
  10.1016/j.celrep.2019.06.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-16H02622
[Journal Article] Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression.2019
- Author(s)
  Fursova NA, Blackledge NP, Nakayama M, Ito S, Koseki Y, Farcas AM, King HW, Koseki H, Klose RJ.
- Journal Title
  
  Molecular Cell
  
  Volume: 印刷中 Pages: 1020-1036
- DOI
  10.1016/j.molcel.2019.03.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05602, KAKENHI-PROJECT-19K06621, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-16H02622
[Journal Article] KDM2B in polycomb repressive complex 1.1 functions as a tumor suppressor in the initiation of T-cell leukemogenesis2019
- Author(s)
  Isshiki Y, Nakajima-Takagi Y, Oshima M, Aoyama K, Rizk M, Kurosawa S, Saraya A, Kondo T, Sakaida E, Nakaseko C, Yokote K, Koseki H, Iwama A.
- Journal Title
  
  Blood Advances
  
  Volume: 3 Pages: 2537-2549
- DOI
  10.1182/bloodadvances.2018028522
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08348, KAKENHI-WRAPUP-19H05442, KAKENHI-PLANNED-19H05745, KAKENHI-PLANNED-19H05746, KAKENHI-PROJECT-19H05653, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-17H01558, KAKENHI-PROJECT-18K19555
[Journal Article] Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 Pathway2018
- Author(s)
  Jansz Natasha、Nesterova Tatyana、Keniry Andrew、Iminitoff Megan、Hickey Peter F.、Pintacuda Greta、Masui Osamu、Kobelke Simon、Geoghegan Niall、Breslin Kelsey A.、Willson Tracy A.、Rogers Kelly、Kay Graham F.、Fox Archa H.、Koseki Haruhiko、Brockdorff Neil、Murphy James M.、Blewitt Marnie E.
- Journal Title
  
  Cell Reports
  
  Volume: 25
- DOI
  10.1016/j.celrep.2018.10.044
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Journal Article] Pivotal role of IL-22 binding protein in the epithelial autoregulation of interleukin-22 signaling in the control of skin inflammation2018
- Author(s)
  Tomohiro Fukaya, Takehito Fukui, Tomofumi Uto, Hideaki Takagi, Junta Nasu, Noriaki, Miyanaga, Keiichi Arimura, Takeshi Nakamura, Haruhiko Koseki, Narantsog Choijookhuu, Yoshitaka Hishikawa, Katsuaki Sato
- Journal Title
  
  Front. Immunol.
  
  Volume: 9 Pages: 1-13
- DOI
  10.3389/fimmu.2018.01418
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15732, KAKENHI-PROJECT-18K15194, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-18H02670, KAKENHI-PROJECT-16K08471
[Journal Article] Physiological Srsf2 P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice.2018
- Author(s)
  Kon Ayana、Yamazaki Satoshi、Nannya Yasuhito、Kataoka Keisuke、Ota Yasunori、Nakagawa Masahiro Marshall、Yoshida Kenichi、Shiozawa Yusuke、Morita Maiko、Yoshizato Tetsuichi、Sanada Masashi、Nakayama Manabu、Koseki Haruhiko、Nakauchi Hiromitsu、Ogawa Seishi
- Journal Title
  
  Blood Adv
  
  Volume: 131 Pages: 621-635
- DOI
  10.1182/blood-2017-01-762393
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-17H05086, KAKENHI-PROJECT-16K19574
[Journal Article] Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome2018
- Author(s)
  Tara S, Isshiki Y, Nakajima-Takagi Y, Oshima M, Aoyama K, Tanaka T, Shinoda D, Koide S, Saraya A, Miyagi S, Manabe I, Matsui H, Koseki H, Bardwell VJ, Iwama A.
- Journal Title
  
  Blood
  
  Volume: 132(23) Pages: 2470-2483
- DOI
  10.1182/blood-2018-01-827964
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08348, KAKENHI-ORGANIZER-26115001, KAKENHI-PLANNED-26115002, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-16K09840, KAKENHI-INTERNATIONAL-15K21751
[Journal Article] Growing oocyte specific transcription-dependent de novo DNA methylation at the imprinted Zrsr1-DMR.2018
- Author(s)
  Joh K, Matsuhisa F, Kitajima S, Nishioka K, Higashimoto K, Yatsuki H, Kono T, Koseki H, Soejima H
- Journal Title
  
  Epigenetics Chromatin
  
  Volume: 11 Pages: 28-28
- DOI
  10.1186/s13072-018-0200-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07138, KAKENHI-PROJECT-17K08687, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-16K09970, KAKENHI-PROJECT-18H00338
[Journal Article] Ubiquitination-Independent Repression of PRC1 Targets during Neuronal Fate Restriction in the Developing Mouse Neocortex2018
- Author(s)
  Masafumi Tsuboi, Yusuke Kishi, Wakana Kyozuka, Haruhiko Koseki, Yusuke Hirabayashi, and Yukiko Gotoh*
- Journal Title
  
  Dev. Cell
  
  Volume: 47 Pages: 758-772
- DOI
  10.1016/j.devcel.2018.11.018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14622, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-15K06947, KAKENHI-PUBLICLY-16H01297, KAKENHI-PLANNED-16H06481, KAKENHI-PROJECT-15H05773
[Journal Article] Ring1A and Ring1B inhibit expression of Glis2 to maintain murineMOZ-TIF2AML stem cells2018
- Author(s)
  Haruko Shima、Emi Takamatsu-Ichihara、Mika Shino、Kazutsune Yamagata、Takuo Katsumoto、Yukiko Aikawa、Shuhei Fujita、Haruhiko Koseki、Issay Kitabayashi
- Journal Title
  
  Blood
  
  Volume: 131 Pages: 1833-1845
- DOI
  10.1182/blood-2017-05-787226
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21646, KAKENHI-PROJECT-16H02622
[Journal Article] PRC1 Fine-tunes Gene Repression and Activation to Safeguard Skin Development and Stem Cell Specification2018
- Author(s)
  Cohen Idan、Zhao Dejian、Bar Carmit、Valdes Victor J.、Dauber-Decker Katherine L.、Nguyen Minh Binh、Nakayama Manabu、Rendl Michael、Bickmore Wendy A.、Koseki Haruhiko、Zheng Deyou、Ezhkova Elena
- Journal Title
  
  Cell Stem Cell
  
  Volume: 22
- DOI
  10.1016/j.stem.2018.04.005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Journal Article] FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment2018
- Author(s)
  Dimitrova Emilia、Kondo Takashi、Feldmann Angelika、Nakayama Manabu、Koseki Yoko、Konietzny Rebecca、Kessler Benedikt M、Koseki Haruhiko、Klose Robert J
- Journal Title
  
  eLife
  
  Volume: 7
- DOI
  10.7554/elife.37084
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Journal Article] Variant PRC1 competes with retinoic acid-related signals to repress Meis2 in the mouse distal forelimb bud2018
- Author(s)
  Yakushiji-Kaminatsui Nayuta、Kondo Takashi、Hironaka Ken-ichi、Sharif Jafar、Endo Takaho A.、Nakayama Manabu、Masui Osamu、Koseki Yoko、Kondo Kaori、Ohara Osamu、Vidal Miguel、Morishita Yoshihiro、Koseki Haruhiko
- Journal Title
  
  Development
  
  Volume: 145
- DOI
  10.1242/dev.166348
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Journal Article] PRC1 preserves epidermal tissue integrity independently of PRC22018
- Author(s)
  Cohen Idan、Zhao Dejian、Menon Gopinathan、Nakayama Manabu、Koseki Haruhiko、Zheng Deyou、Ezhkova Elena
- Journal Title
  
  Genes & Development
  
  Volume: 33 Pages: 55-60
- DOI
  10.1101/gad.319939.118
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Journal Article] 1.PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes2017
- Author(s)
  Endoh M, Endo TA, Shinga J, Hayashi K, Farcas A, Ma KW, Ito S, Sharif J, Endoh T, Onaga N, Nakayama M, Ishikura T, Masui O, Kessler BM, Suda T, Ohara O, Okuda A, Klose RJ, Koseki H.
- Journal Title
  
  Elife.
  
  Volume: 6 Pages: 27970-27970
- DOI
  10.7554/elife.21064
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-15H05602, KAKENHI-PROJECT-16K07372, KAKENHI-PROJECT-16K14773, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-26221309
[Journal Article] Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells.2017
- Author(s)
  Choi J, Huebner AJ, Clement K, Walsh RM, Savol A, Lin K, Gu H, Di Stefano B, Brumbaugh J, Kim SY, Sharif J, Rose CM, Mohammad A, Odajima J, Charron J, Shioda T, Gnirke A, Gygi S, Koseki H, Sadreyev RI, Xiao A, Meissner A, Hochedlinger K.
- Journal Title
  
  Nature
  
  Volume: 548 Pages: 219-223
- DOI
  10.1038/nature23274
- Open Access
- Data Source
  KAKENHI-PROJECT-16H02622
[Journal Article] Internal deletion of BCOR reveals a tumor suppressor function for BCOR in T lymphocyte malignancies.2017
- Author(s)
  Tanaka Tomoyuki、Nakajima-Takagi Yaeko、Aoyama Kazumasa、Tara Shiro、Oshima Motohiko、Saraya Atsunori、Koide Shuhei、Si Sha、Manabe Ichiro、Sanada Masashi、Nakayama Manabu、Masuko Masayoshi、Sone Hirohito、Koseki Haruhiko、Iwama Atsushi
- Journal Title
  
  J. Exp. Med.
  
  Volume: 214 Pages: 2901-2913
- DOI
  10.1084/jem.20170167
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09868, KAKENHI-PROJECT-17K10136, KAKENHI-ORGANIZER-26115001, KAKENHI-PLANNED-26115002, KAKENHI-PROJECT-15H02544, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-16K15498, KAKENHI-PROJECT-16K19565, KAKENHI-PROJECT-16K20959
[Journal Article] PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation2017
- Author(s)
  Almeida M, Pintacuda G, Masui O, Koseki Y, Gdula M, Cerase A, Brown D, Mould A, Innocent C, Nakayama M, Schermelleh L, Nesterova TB, Koseki H, Brockdorff N.
- Journal Title
  
  Science
  
  Volume: 356 Pages: 1081-1084
- DOI
  10.1126/science.aal2512
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-16K14773
[Journal Article] Crosstalk between NRF2 and HIPK2 shapes cytoprotective responses.2017
- Author(s)
  Torrente L, Sanchez C, Moreno R, Chowdhry S, Cabello P, Isono K, Koseki H, Honda T, Hayes JD, Dinkova-Kostova AT, de la Vega L.
- Journal Title
  
  Oncogene
  
  Volume: 36 Pages: 6204-6212
- DOI
  10.1038/onc.2017.221
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Journal Article] Polycomb directs timely activation of germline genes in spermatogenesis2017
- Author(s)
  Maezawa S, Hasegawa K, Yukawa M, Sakashita A, Alavattam KG, Andreassen PR, Vidal M, Koseki H, Barski A, Namekawa SH.
- Journal Title
  
  Genes Dev
  
  Volume: 31 Pages: 1693-1703
- DOI
  10.1101/gad.302000.117
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Journal Article] EPC1/TIP60-mediated histone acetylation facilitates spermiogenesis in mice.2017
- Author(s)
  Dong Yixin、Isono Kyo-ichi、Ohbo Kazuyuki、Endo Takaho A.、Ohara Osamu、Maekawa Mamiko、Toyama Yoshiro、Ito Chizuru、Toshimori Kiyotaka、Helin Kristian、Ogonuki Narumi、Inoue Kimiko、Ogura Atsuo、Yamagata Kazutsune、Kitabayashi Issay、Koseki Haruhiko
- Journal Title
  
  Mol Cell Biol
  
  Volume: 37
- DOI
  10.1128/mcb.00082-17
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08156, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-15K10638
[Journal Article] CFC1 is a cancer stemness-regulating factor in neuroblastoma.2017
- Author(s)
  Chikaraishi Koji、Takenobu Hisanori、Sugino Ryuichi P.、Mukae Kyosuke、Akter Jesmin、Haruta Masayuki、Kurosumi Masafumi、Endo Takaho A.、Koseki Haruhiko、Shimojo Naoki、Ohira Miki、Kamijo Takehiko
- Journal Title
  
  Oncotarget
  
  Volume: 8 Pages: 45046-45059
- DOI
  10.18632/oncotarget.18464
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10051, KAKENHI-PROJECT-17K10131, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-17H01592, KAKENHI-PROJECT-17K19623
[Journal Article] An endosiRNA-Based Repression Mechanism Counteracts Transposon Activation during Global DNA Demethylation in Embryonic Stem Cells.2017
- Author(s)
  Berrens RV, Andrews S, Spensberger D, Santos F, Dean W, Gould P, Sharif J, Olova N, Chandra T, Koseki H, von Meyenn F, Reik W.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 21 Pages: 694-703
- DOI
  10.1016/j.stem.2017.10.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Journal Article] Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.2017
- Author(s)
  Graf U, Casanova EA, Wyck S, Dalcher D, Gatti M, Vollenweider E, Okoniewski MJ, Weber FA, Patel SS, Schmid MW, Li J, Sharif J, Wanner GA, Koseki H, Wong J, Pelczar P, Penengo L, Santoro R, Cinelli P.
- Journal Title
  
  Nat Cell Biol
  
  Volume: 19 Pages: 763-773
- DOI
  10.1038/ncb3554
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Journal Article] The SET1 Complex Selects Actively Transcribed Target Genes via Multivalent Interaction with CpG Island Chromatin2017
- Author(s)
  Brown DA, Di Cerbo V, Feldmann A, Ahn J, Ito S, Blackledge NP, Nakayama M, McClellan M, Dimitrova E, Turberfield AH, Long HK, King HW, Kriaucionis S, Schermelleh L, Kutateladze T, Koseki H, Klose RJ.
- Journal Title
  
  Cell Rep.
  
  Volume: 20 Pages: 2313-2327
- DOI
  10.1016/j.celrep.2017.08.030
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-15H05602
[Journal Article] Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos2017
- Author(s)
  Maenohara S, Unoki M, Toh H, Ohishi H, Sharif, J, Koseki, H, Sasaki H.
- Journal Title
  
  PLOS Genetics
  
  Volume: 13
- DOI
  10.1371/journal.pgen.1007042
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112010, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-15K06803
[Journal Article] No Winter Lasts Forever: Polycomb Complexes Convert Epigenetic Memory of Cold into Flowering2017
- Author(s)
  Sharif J, Koseki H.
- Journal Title
  
  Dev Cell
  
  Volume: 42 Pages: 563-564
- DOI
  10.1016/j.devcel.2017.09.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02622
[Journal Article] Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways.2017
- Author(s)
  Jullien J, Vodnala M, Pasque V, Oikawa M, Miyamoto K, Allen G, David SA, Brochard V, Wang S, Bradshaw C, Koseki H, Sartorelli V, Beaujean N, Gurdon　J
- Journal Title
  
  Mol Cell.
  
  Volume: 65 Pages: 873-884
- DOI
  10.1016/j.molcel.2017.01.030
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01321, KAKENHI-PROJECT-16H02622, KAKENHI-ORGANIZER-25112001, KAKENHI-PUBLICLY-16H01222, KAKENHI-INTERNATIONAL-15K21737
[Journal Article] Functional analysis of AEBP2, a PRC2 Polycomb protein, reveals a Trithorax phenotype in embryonic development and in ESCs.2016
- Author(s)
  Grijzenhout A, Godwin J, Koseki H, Gdula MR, Szumska D, McGouran JF, Bhattacharya S, Kessler BM, Brockdorff N, Cooper S
- Journal Title
  
  Development
  
  Volume: 143 Pages: 2716-2723
- DOI
  10.1242/dev.123935
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Journal Article] RING1 proteins contribute to early proximal-distal specification of the forelimb bud by restricting Meis2 expression2016
- Author(s)
  Yakushiji-Kaminatsui, N., Kondo, T., Endo, T.A., Koseki, Y., Kondo, K., Ohara, O., Vidal, M. and Koseki, H.
- Journal Title
  
  Development
  
  Volume: 143 Pages: 276-285
- DOI
  10.1242/dev.127506
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15076, KAKENHI-PROJECT-23249015
[Journal Article] Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of B lineage program.2016
- Author(s)
  Ikawa T, Masuda K, Endo TA, Endo M, Isono K, Koseki Y, Nakagawa R, Kometani K, Takano J, Agata Y, Katsura Y, Kurosaki T, Vidal M, Koseki H, Kawamoto H.
- Journal Title
  
  Genes & Development
  
  Volume: 30 Pages: 2475-2485
- DOI
  10.1101/gad.290593.116
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-15H04743, KAKENHI-PROJECT-26670136, KAKENHI-PROJECT-16K07372, KAKENHI-PROJECT-16K09870, KAKENHI-PROJECT-16K15289, KAKENHI-PROJECT-16K15215
[Journal Article] Loss of Pcgf5 Affects Global H2A Monoubiquitination but Not the Function of Hematopoietic Stem and Progenitor Cells.2016
- Author(s)
  Si S, Nakajima-Takagi Y, Aoyama K, Oshima M, Saraya A, Sugishita H, Nakayama M, Ishikura T, Koseki H, Iwama A
- Journal Title
  
  PLoS One.
  
  Volume: 11
- DOI
  10.1371/journal.pone.0154561
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-14J40042, KAKENHI-PROJECT-15K19544, KAKENHI-PROJECT-16K19565, KAKENHI-PROJECT-16K20959
[Journal Article] ThPOK represses CXXC5, which induces methylation of histone H3 lysine 9 in Cd40lg promoter by association with SUV39H1: implications in repression of CD40L expression in CD8+ cytotoxic T cells.2016
- Author(s)
  Tsuchiya Y, Naito T, Tenno M, Maruyama M, Koseki H, Taniuchi I, Naoe Y.
- Journal Title
  
  J Leukoc Biol
  
  Volume: 印刷中 Pages: 327-338
- DOI
  10.1189/jlb.1a0915-396rr
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26114720, KAKENHI-PROJECT-26293109, KAKENHI-PROJECT-16H02622
[Journal Article] De novo DNA methylation drives 5hmC accumulation in mouse zygotes2016
- Author(s)
  Amouroux R, Nashun B, Shirane K, Nakagawa S, Hill PW, D'Souza Z, Nakayama M, Matsuda M, Turp A, Ndjetehe E, Encheva V, Kudo NR, Koseki H, Sasaki H, Hajkova P.
- Journal Title
  
  Nature Cell Biology
  
  Volume: 18 Pages: 225-233
- DOI
  10.1038/ncb3296
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21737, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112010, KAKENHI-PROJECT-23249015, KAKENHI-PROJECT-14J04310
[Journal Article] Activation of Endogenous Retroviruses in Dnmt1-/-ESCs Involves Disruption of SETDB1-Mediated Repression by NP95 Binding to Hemimethylated DNA2016
- Author(s)
  Sharif J, Endo TA, Nakayama M, Karimi MM, Shimada M, Katsuyama K, Goyal P, Brind'Amour J, Sun MA, Sun Z, Ishikura T, Mizutani-Koseki Y, Ohara O, Shinkai Y, Nakanishi M, Xie H, Lorincz MC, Koseki H.
- Journal Title
  
  Cell Stem Cell.
  
  Volume: Epub ahead of print Pages: 81-81
- DOI
  10.1016/j.stem.2016.03.013
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870847, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-15K08280, KAKENHI-PROJECT-16K15239, KAKENHI-PROJECT-26250027
[Journal Article] Histone H2A T120 phosphorylation promotes oncogenic transformation via upregulation of cyclin D1.2016
- Author(s)
  Aihara H
- Journal Title
  
  Mol Cell.
  
  Volume: 64 Pages: 176-188
- DOI
  10.1016/j.molcel.2016.09.012
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01307, KAKENHI-PLANNED-24118003, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-26281020, KAKENHI-PROJECT-15K12203, KAKENHI-PROJECT-15K15353, KAKENHI-PROJECT-16K07201, KAKENHI-PROJECT-15K15581, KAKENHI-PROJECT-16K19040
[Journal Article] Polycomb Complex PRC1 Preserves Intestinal Stem Cell Identity by Sustaining Wnt/β-Catenin Transcriptional Activity2015
- Author(s)
  Chiacchiera F, Rossi A, Jammula S, Piunti A, Scelfo A, Ordóñez-Morán P, Huelsken J, Koseki H, Pasini D
- Journal Title
  
  Cell Stem Cell
  
  Volume: 18 Pages: 91-103
- DOI
  10.1016/j.stem.2015.09.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23249015
[Journal Article] Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome2015
- Author(s)
  Schoenfelder S, Sugar R, Dimond A, Javierre BM, Armstrong H, Mifsud B, Dimitrova E, Matheson L, Tavares-Cadete F, Furlan-Magaril M, Segonds-Pichon A, Jurkowski W, Wingett SW, Tabbada K, Andrews S, Herman B, LeProust E, Osborne CS, Koseki H, Fraser P, Luscombe NM, Elderkin S
- Journal Title
  
  Nat Genet.
  
  Volume: 47 Pages: 1179-86
- DOI
  10.1038/ng.3393
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23249015
[Journal Article] Nuclear transcriptome profiling of induced pluripotent stem cells and embryonic stem cells identify non-coding loci resistant to reprogramming2015
- Author(s)
  Fort A, Yamada D, Hashimoto K, Koseki H, Carninci P
- Journal Title
  
  Cell Cycle
  
  Volume: 14 Pages: 1148-55
- DOI
  10.4161/15384101.2014.988031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23249015
[Journal Article] Generating a transgenic mouse line stably expressing human MHC surface antigen from a HAC carrying multiple genomic BACs.2015
- Author(s)
  Hasegawa Y, Ishikura T, Hasegawa T, Watanabe T, Suzuki J, Nakayama M, Okamura Y, Okazaki T, Koseki H, Ohara O, Ikeno M, and Masumoto H
- Journal Title
  
  Chromosoma
  
  Volume: 124(1) Pages: 107-118
- DOI
  10.1007/s00412-014-0488-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23114008, KAKENHI-PROJECT-24310143
[Journal Article] A novel de novo point mutation of OCT-binding site in the IGF2/H19-imprinting control region in a patient with Beckwith-Wiedemann syndrome2014
- Author(s)
  Higashimoto K, Jozaki K, Kosho T, Matsubara K, Sato T, Yamada D, Yatsuki H, Maeda T, Ohtsuka Y, Nishioka K, Joh K, Koseki H, Ogata T, SoejimaH*
- Journal Title
  
  Clin Genet.
  
  Volume: in press Pages: 539-44
- DOI
  10.1111/cge.12318
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22132004, KAKENHI-PROJECT-22227002, KAKENHI-PROJECT-23249015, KAKENHI-PROJECT-23659181, KAKENHI-PROJECT-25253023, KAKENHI-PROJECT-25461554, KAKENHI-PROJECT-25461648, KAKENHI-PROJECT-25860898, KAKENHI-PROJECT-26670169
[Journal Article] Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment2014
- Author(s)
  Cooper S, Dienstbier M, Hassan R, Schermelleh L, Sharif J, Blackledge NP, De Marco V, Elderkin S, Koseki H, Klose R, Heger A, Brockdorff N
- Journal Title
  
  Cell Reports
  
  Volume: 7 Pages: 1456-70
- DOI
  10.1016/j.celrep.2014.04.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23249015
[Journal Article] Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication.2014
- Author(s)
  Nishiyama, A
- Journal Title
  
  Nature.
  
  Volume: 502 Pages: 249-253
- DOI
  10.1038/nature12488
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118003, KAKENHI-PROJECT-23240124, KAKENHI-PROJECT-23249015, KAKENHI-PUBLICLY-24113711, KAKENHI-PROJECT-24659137, KAKENHI-PROJECT-24790290, KAKENHI-PUBLICLY-25131717, KAKENHI-PROJECT-25461659
[Journal Article] The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells.2014
- Author(s)
  Yuuki Obata*, Yukihiro Furusawa*, Takaho A. Endo, Jafar Sharif, Daisuke Takahashi, Koji Atarashi, Manabu Nakayama, Satoshi Onawa, Yumiko Fujimura, Masumi Takahashi, Tomokatsu Ikawa, Takeshi Otsubo, Yuki I. Kawamura, Taeko Dohi, Shoji Tajima, Osamu Ohara, Kenya Honda, Shohei Hori, Hiroshi Ohno, Haruhiko Koseki and Koji Hase. 【* : 筆頭筆者】
- Journal Title
  
  Nat. Immunol.
  
  Volume: 15 Pages: 571-579
- DOI
  10.1038/ni.2886
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J02667, KAKENHI-PLANNED-23114008, KAKENHI-PROJECT-23247030, KAKENHI-PROJECT-23249015, KAKENHI-PUBLICLY-24117723, KAKENHI-PROJECT-24689042, KAKENHI-PROJECT-24890293, KAKENHI-PUBLICLY-25118732, KAKENHI-PUBLICLY-25118733, KAKENHI-PROJECT-25291025, KAKENHI-PROJECT-25293114, KAKENHI-PROJECT-25460965, KAKENHI-PUBLICLY-26116709, KAKENHI-PROJECT-26293229, KAKENHI-PROJECT-26670472
[Journal Article] Stem cell epigenetics: looking forward2014
- Author(s)
  Benitah SA, Bracken A, Dou Y, Huangfu D, Ivanova N, Koseki H, Laurent L, Lim DA, Meshorer E, Pombo A, Sander M, Xu GL
- Journal Title
  
  Cell Stem Cell
  
  Volume: 14 Pages: 706-9
- DOI
  10.1016/j.stem.2014.05.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23249015
[Journal Article] Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation2014
- Author(s)
  Blackledge NP, Farcas AM, Kondo T, King HW, McGouran JF, Hanssen LL, Ito S, Cooper S, Kondo K, Koseki Y, Ishikura T, Long HK, Sheahan TW, Brockdorff N, Kessler BM, Koseki H, Klose RJ
- Journal Title
  
  Cell
  
  Volume: 157 Pages: 1445-59
- DOI
  10.1016/j.cell.2014.05.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23249015
[Journal Article] Haploinsufficiency of Sf3b1 leads to compromised stem cell function but not to myelodysplasia2014
- Author(s)
  Matsunawa M, Yoshida K
- Journal Title
  
  Leukemia.
  
  Volume: (Epub ahead of print) Pages: 1844-1850
- DOI
  10.1038/leu.2014.73
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J04216, KAKENHI-PLANNED-22134006, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23249052, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24390242, KAKENHI-PROJECT-24659458, KAKENHI-PROJECT-25670152, KAKENHI-PROJECT-25670446, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-26640075, KAKENHI-PROJECT-26890016
[Journal Article] Deep transcriptome profiling of mammalian stem cells supports a regulatory role for retrotransposons in pluripotency maintenance2014
- Author(s)
  Fort A, Hashimoto K, Yamada D, Salimullah M, Keya CA, Saxena A, Bonetti A, Voineagu I, Bertin N, Kratz A, Noro Y, Wong CH, de Hoon M, Andersson R, Sandelin A, Suzuki H, Wei CL, Koseki H; FANTOM Consortium, Hasegawa Y, Forrest AR, Carninci P
- Journal Title
  
  Nature Genetics
  
  Volume: 46 Pages: 558-66
- DOI
  10.1038/ng.2965
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23249015
[Journal Article] The Polycomb Potentiates Meis2 Activation in Midbrain by Mediating Interaction of the Promoter with a Tissue-Specific Enhancer.2014
- Author(s)
  Kondo T., Isono K, Kondo K, Endo TA, Itohara S, Vidal M, and Koseki H.
- Journal Title
  
  Dev Cell.
  
  Volume: 28 Pages: 94-101
- DOI
  10.1016/j.devcel.2013.11.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249015
[Journal Article] Generation of rejuvenated antigen-specific T cells by pluripotency reprogramming and redifferentiation.2013
- Author(s)
  Nishimura T, Koseki H, Nakauchi H.　他
- Journal Title
  
  Cell StemCell.
  
  Volume: 12 Pages: 114-126
- DOI
  10.1016/j.stem.2012.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249015, KAKENHI-PROJECT-23591413, KAKENHI-PROJECT-23592022, KAKENHI-PROJECT-23650622, KAKENHI-PROJECT-23791154, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-24390257, KAKENHI-PLANNED-23106004
[Journal Article] KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands2013
- Author(s)
  Farcas AM
- Journal Title
  
  elife.
  
  Volume: 1
- DOI
  10.7554/elife.00205
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062014, KAKENHI-PROJECT-23249015
[Journal Article] Repression of Bach2 contributes to predisposition of IgG1 memory B cells toward plasma cell differentiation.2013
- Author(s)
  Kometani K, Nakagawa R, Shinnakasu R, Kaji T, Rybouchkin A, Moriyama S, Furukawa K, Koseki H, Takemori T, Kurosaki T.
- Journal Title
  
  Immunity
  
  Volume: 39 Pages: 136-147
- DOI
  10.1016/j.immuni.2013.06.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249015, KAKENHI-PROJECT-24790487
[Journal Article] An epigenetic switch is crucial for spermatogonia to exit the undifferentiated state toward a Kit-positive identity.2013
- Author(s)
  Shirakawa, T., Yaman-Deveci, R., Tomizawa, S., Kamizato, Y., Nakajima, K., Sone, H., Sato, Y., Sharif, J., Yamashita, A., Takada-Horisawa, Y., Yoshida, S., Ura, K., Muto, M., Koseki, H., Suda, T., and Ohbo, K.
- Journal Title
  
  Development.
  
  Volume: 140 Pages: 3565-3576
- DOI
  10.1242/dev.094045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11J09354, KAKENHI-PLANNED-20116004, KAKENHI-PLANNED-21115004, KAKENHI-PLANNED-22131003, KAKENHI-PROJECT-23249015, KAKENHI-PROJECT-23687025, KAKENHI-PROJECT-24247041, KAKENHI-PLANNED-25114004, KAKENHI-PROJECT-25670097
[Journal Article] Dependence receptor UNC5D mediates nerve growth factor depletion-induced neruoblastoma regression.2013
- Author(s)
  Zhu Y, Li Y, Haraguchi S, Yu M, Ohira M, Ozaki T, Nakagawa A, Ushijima T, Isogai E, Koseki H, Nakamura Y, Kong C, Mehlen P, Arakawa H, Nakagawara A.
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 123 Pages: 2935-2947
- DOI
  10.1172/jci65988
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249015, KAKENHI-PROJECT-23501278, KAKENHI-PROJECT-23591562, KAKENHI-PROJECT-24249061, KAKENHI-PROJECT-24591566, KAKENHI-PROJECT-24592703, KAKENHI-PROJECT-25670169
[Journal Article] Regeneration of Human Tumor Antigen-Specific T Cells from iPSCs Derived from Mature CD8(+) T Cells.2013
- Author(s)
  Vizcardo, R
- Journal Title
  
  Blood
  
  Volume: 12 Pages: 31-36
- DOI
  10.1016/j.stem.2012.12.006
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22118001, KAKENHI-PROJECT-23249015, KAKENHI-PROJECT-23380186, KAKENHI-PROJECT-24249057, KAKENHI-PROJECT-24689042, KAKENHI-PROJECT-24790486, KAKENHI-PLANNED-22118004
[Journal Article] SAM domain polymerization links subnuclear clustering of PRC1 to gene silencing.2013
- Author(s)
  Isono K, Endo TA, Ku M, Yamada D, Suzuki R, Sharif J, Ishikura T, Toyoda T, Bernstein BE, Koseki H.
- Journal Title
  
  Developmental Cell
  
  Volume: 26 Pages: 565-577
- DOI
  10.1016/j.devcel.2013.08.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249015, KAKENHI-PROJECT-25670152
[Journal Article] Is there a role for endogenous retroviruses to mediate long-term adaptive phenotypic response upon environmental inputs?2013
- Author(s)
  Sharif J
- Journal Title
  
  Philos Trans R Soc Lond B Biol Sci.
  
  Volume: 368
- DOI
  10.1098/rstb.2011.0340
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062014, KAKENHI-PROJECT-23249015
[Journal Article] Role of SOX17 in hematopoietic development from human embryonic stem cells2013
- Author(s)
  Nakajima-Takagi Y, Osawa M, Oshima M, Takagi H, Miyagi S, Endoh M, Endo TA, Takayama N, Eto K, Toyoda T, Koseki H, Nakauchi H, Iwama A.
- Journal Title
  
  Blood
  
  Volume: 121 Pages: 447-458
- DOI
  10.1182/blood-2012-05-431403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249015, KAKENHI-PROJECT-23650622, KAKENHI-PROJECT-23791071, KAKENHI-PROJECT-23791154, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-24591381, KAKENHI-PLANNED-23106004, KAKENHI-PUBLICLY-23130502, KAKENHI-PUBLICLY-24116711
[Journal Article] CCN3 protein participates in bone regeneration as an inhibitory factor2013
- Author(s)
  Matsushita Y, Sakamoto K, Tamamura Y, Shibata Y, Minamizato T, Kihara T, Ito M, Katsube K, Hiraoka S, Koseki H, Harada K, Yamaguchi A.
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Pages: 19973-19985
- DOI
  10.1074/jbc.m113.454652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390428, KAKENHI-PROJECT-23249015, KAKENHI-PROJECT-23592696, KAKENHI-PROJECT-25253098, KAKENHI-PROJECT-25462915, KAKENHI-PROJECT-25670170
[Journal Article] UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9.2013
- Author(s)
  Liu X, Gao Q, Li P, Zhao Q, Zhang J, Li J, Koseki H, Wong J.
- Journal Title
  
  Nat Commun.
  
  Volume: 4 Pages: 1563-1563
- DOI
  10.1038/ncomms2562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249015
[Journal Article] WIP1, a homeostatic regulator of the DNA damage response, is targeted by HIPK2 for phosphorylation and degradation.2013
- Author(s)
  Choi DW, Na W, Kabir MH, Yi E, Kwon S, Yeom J, Ahn JW, Choi HH, Lee Y, Seo KW, Shin MK, Park SH, Yoo HY, Isono K, Koseki H, Kim ST, Lee C, Kwon YK, Choi CY.
- Journal Title
  
  Mol Cell.
  
  Volume: 51 Pages: 374-85
- DOI
  10.1016/j.molcel.2013.06.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249015
[Journal Article] RYBP represses endogenous retroviruses and preimplantation- and germ line-specific genes in mouse embryonic stem cells.2012
- Author(s)
  Hisada K, Sanchez C, Endo TA, Endoh M, Roman-Trufero M, Sharif J, Koseki H, Vidal M.
- Journal Title
  
  Mol Cell Biol.
  
  Volume: 32 Pages: 1139-49
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062014
[Journal Article] RYBP represses endogenous retroviruses, preimplantation-and germline-specific genes in mouse embryonic stem cells2012
- Author(s)
  Hisada K, Sanchez C, Endo T, Endoh M, Roman-Trufero M, Sharif J, Koseki H, Vidal M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 32 Pages: 1139-1149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21602006
[Journal Article] Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity2012
- Author(s)
  Endoh M, Endo TA, Endoh T, Isono K, Sharif J, Ohara O, Toyoda T, Ito T, Eskeland R, Bickmore WA, Vidal M, Bernstein BE, Koseki H.
- Journal Title
  
  PLoS Genetics
  
  Volume: 8
- DOI
  10.1371/journal.pgen.1002774
- NAID
  120006985569
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062014, KAKENHI-PROJECT-22590278, KAKENHI-PUBLICLY-23131510, KAKENHI-PROJECT-23249015, KAKENHI-PLANNED-24118003, KAKENHI-PUBLICLY-24116711, KAKENHI-ORGANIZER-24118001
[Journal Article] H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions.2012
- Author(s)
  Ku M, Jaffe JD, Koche RP, Rheinbay E, Endoh M, Koseki H, Carr SA, Bernstein BE.
- Journal Title
  
  Genome Biol.
  
  Volume: 13
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062014
[Journal Article] HP1γ links histone methylation marks to meiotic synapsis in mice.2011
- Author(s)
  Takada Y, Naruse C, Costa Y, Shirakawa T, Tachibana M, Sharif J, Kezuka-Shiotani F, Kakiuchi D, Masumoto H, Shinkai Y, Ohbo K, Peters AH, Turner JM, Asano M, Koseki H.
- Journal Title
  
  Development
  
  Volume: 138 Pages: 4207-17
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062014
[Journal Article] Mammalian Polycomblike Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate Polycomb activity at both the Hox gene cluster and at Cdkn2a genes.2011
- Author(s)
  Li X, Isono KI, Yamada D, Endo TA, Endoh M, Shinga J, Mizutani-Koseki Y, Otte AP, Casanova M, Kitamura H, Kamijo T, Sharif J, Ohara O, Toyada T, Bernstein BE, Brockdorff N, Koseki H.
- Journal Title
  
  Mol Cell Biol.
  
  Volume: 31 Pages: 351-364
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062014
[Journal Article] Genome-wide analysis of target genes regulated by HoxB4 in hematopoietic stem and progenitor cells developing from embryonic stem cells2011
- Author(s)
  Oshima M, Endoh M, Endo TA, Toyoda T, Nakajima-Takagi Y, Sugiyama F, Koseki H, Kyba M, Iwama A, Osawa M
- Journal Title
  
  Blood
  
  Volume: 117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21602006
[Journal Article] Epigenetic memory meets G2/M : to remember or to forget2011
- Author(s)
  Sharif J, Endoh M, Koseki H
- Journal Title
  
  Dev Cell
  
  Volume: 20 Pages: 5-6
- Data Source
  KAKENHI-PROJECT-21602006
[Journal Article] Mammalian Polycomblike Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate Polycomb activity at both the Hox gene cluster and at Cdkn2a genes2011
- Author(s)
  Li X, Isono KI, Yamada D, Endo TA, Endoh M, Shinga J, Mizutani-Koseki Y, Otte AP, Casanova M, Kitamura H, Kamijo T, Sharif J, Ohara O, Toyada T, Bernstein BE, Brockdorff N, Koseki H
- Journal Title
  
  Mol Cell Biol.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390088
[Journal Article] Polycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells.2011
- Author(s)
  Casanova M, Preissner T, Cerase A, Poot R, Yamada D, Li X, Appanah R, Bezstarosti K, Demmers J, Koseki H, Brockdorff N.
- Journal Title
  
  Development
  
  Volume: 138 Pages: 1471-82
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062014
[Journal Article] The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis2011
- Author(s)
  Mishima Y, Miyagi S, Saraya A, Negishi M, Endoh M, Endo TA, Toyoda T, Shinga J, Katsumoto T, Chiba T, Yamaguchi N, Kitabayashi I, Koseki H, Iwama A
- Journal Title
  
  Blood
  
  Volume: 118 Pages: 2443-2453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21602006
[Journal Article] Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes2011
- Author(s)
  Li X, Isono K, Yamada D, Endo TA, Endoh M, Shinga J, Mizutani-Koseki Y, Otte AP, Casanova M, Kitamura H, Kamijo T, Sharif J, Ohara O, Toyada T, Bernstein BE, Brockdorff N, Koseki H
- Journal Title
  
  Mol Cell Biol
  
  Volume: 31 Pages: 351-364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21602006
[Journal Article] Reproductive isolation in hybrid mice due to spermatogenesis defects at three meiotic stages. Spermatogenic Disruptions at Three Meiotic Stages in Hybrid Males Between House Mouse Subspecies or Species.2010
- Author(s)
  Oka A, Mita A, Takada Y, Koseki H, Shiroishi T.
- Journal Title
  
  Genetics
  
  Volume: 186 Pages: 339-351
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062014
[Journal Article] ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency2010
- Author(s)
  Pereira CF, Piccolo FM, Tsubouchi T, Sauer S, Ryan NK, Bruno L, Landeira D, Santos J, Banito A, Gil J, Koseki H, Merkenschlager M, Fisher AG
- Journal Title
  
  Cell Stem Cell. 6
  
  Pages: 547-556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390088
[Journal Article] ESCs require PRC2 to direct the successful reprog ramming of differentiated cells toward pluripotency2010
- Author(s)
  Pereira CF, Piccolo FM, Tsubouchi T, Sauer S, Ryan NK, Bruno L, Landeira D, Santos J, Banito A, Gil J, Koseki H, Merkenschlager M, Fisher AG.
- Journal Title
  
  Cell Stem Cell 6
  
  Pages: 547-556
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062014
[Journal Article] Mammalian Polycomblike Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate Polycomb activity at both the Hox gene cluster and at Cdkn2a genes2010
- Author(s)
  Li X, Isono KI, Yamada D, Endo TA, Endoh M, Shinga J, Mizutani-Koseki Y, Otte AP, Casanova M, Kitamura H, Kamijo T, Sharif J, Ohara O, Toyada T, Bernstein BE, Brockdorff N, Koseki H.
- Journal Title
  
  Mol Cell Biol
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062014
[Journal Article] Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells.2010
- Author(s)
  Majewski IJ, Ritchie ME, Phipson B, Corbin J, Pakusch M, Ebert A, Busslinger M, Koseki H, Hu Y, Smyth GK, Alexander WS, Hilton DJ, Blewitt ME.
- Journal Title
  
  Blood.
  
  Volume: 116 Pages: 731-739
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062014
[Journal Article] ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency.2010
- Author(s)
  Pereira CF, Piccolo FM, Tsubouchi T, Sauer S, Ryan NK, Bruno L, Landeira D, Santos J, Banito A, Gil J, Koseki H, Merkenschlager M, Fisher AG.
- Journal Title
  
  Cell Stem Cell.
  
  Volume: 6 Pages: 547-556
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062014
[Journal Article] ヒストンH2Aのユビキチン化による遺伝子発現の制御2009
- Author(s)
  遠藤充浩、古関明彦
- Journal Title
  
  生体の科学
  
  Volume: 60巻 Pages: 533-540
- Data Source
  KAKENHI-PROJECT-21602006
[Journal Article] Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition.2009
- Author(s)
  Yusuke Hirabayashi, Nao Suzki, Masafumi Tsuboi, Takaho A Endo, Tetsuro Toyoda, Jun Shinga, Haruhiko Koseki, Miguel Vidal, Yukiko Gotoh
- Journal Title
  
  Neuron 63(5)
  
  Pages: 600-613
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770231
[Journal Article] Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition2009
- Author(s)
  Hirabayashi Y, Suzki N, Tsuboi M, Endo TA, Toyoda T, Shinga J, Koseki H, Vidal M, Gotoh Y
- Journal Title
  
  Neuron 63
  
  Pages: 600-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21770231
[Journal Article] Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity2008
- Author(s)
  Endoh M., Endo T.A., Endoh T., Fujimura Y., Ohara O., Toyoda T., Otte A.P., Okano M., Brockdorff N., Vidal M., Koseki H.
- Journal Title
  
  Development 135
  
  Pages: 1513-1524
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062014
[Journal Article] Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity2008
- Author(s)
  Endoh M., Endo T.A., Endoh T., Fujimura Y., Ohara O., Toyoda T., Otte A.P., Okano M., Brockdorff N., Vidal M., Koseki H.
- Journal Title
  
  Development 135
  
  Pages: 1513-1524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390088
[Journal Article] PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos.2008
- Author(s)
  Puschendorf M, Terranova R, Boutsma E, Mao X, Isono K, Brykczynska U, Kolb C, Otte AP, Koseki H, Orkin SH, van Lohuizen M, Peters AH.
- Journal Title
  
  Nat Genet.
  
  Volume: 40 Pages: 411-20
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062014
[Journal Article] Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains2008
- Author(s)
  Ku M, Koche RP, Rheinbay E, Mendenhall EM, Endoh M, Mikkelsen TS, Presser A, Nusbaum C, Xie X, Chi AS, Adli M, Kasif S, Ptaszek LM, Cowan CA, Lander ES, Koseki H, Bernstein BE
- Journal Title
  
  PLoS Genet. 4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390088
[Journal Article] Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains2008
- Author(s)
  Ku M, Koche RP, Rheinbay E, Mendenhall EM, Endoh M, Mikkelsen TS, Presser A, Nusbaum C, Xie X, Chi AS, Adli M, Kasif S, Ptaszek LM, Cowan CA, Lander ES, Koseki H, Bernstein BE.
- Journal Title
  
  PLoS Genet 4
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20062014
[Journal Article] 生殖細胞の発生分化のエピジェネティクス2007
- Author(s)
  高田幸、古関明彦
- Journal Title
  
  蛋白質核酸酵素 52
  
  Pages: 2163-2169
- Data Source
  KAKENHI-PROJECT-18051019
[Journal Article] Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes2007
- Author(s)
  Y.Takada, Isono, K., Shinga, J., Turner, J.M.A, Kitamura, H., Ohara, 0., Watanabe, G, Singh, P.B, Kamijo, T., Jenuwein, T., Burgoyne, P.S, Koseki, H
- Journal Title
  
  Development 134.3
  
  Pages: 579-590
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15200032
[Journal Article] Control of developmental regulators by Polycomb in human embryonic stem cells2006
- Author(s)
  T.I.Lee, Jenner, R.G., Boyer, L.A., Guenther, M.G., Levine, S.S., Kumar, R.M., Chevalier, B., Johnstone, S.E., Cole, M.F., Isono, K, Koseki, H., Fuchikami, T., Abe, K., Murray, H.L, Zucker, J.P., Yuan, B., Bell, G.W., Herbolsheimer, E., Hannett, N.M., Sun, K., Odom, D.T., Otte, A.P., Volkert, T.L, Bartel, D.P., Melton, D.A., Gifford, D.K., Jaenisch, R., Young, R.A.
- Journal Title
  
  Cell 125
  
  Pages: 301-313
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15200032
[Journal Article] Overlapping roles for homeodomain-interacting protein kinases Hipkl and Hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals.2006
- Author(s)
  Isono, K., Nemoto, K., Li, Y., Takada, Y., Suzuki, R., Katsuki, M., Nakagawara, A., Koseki, H.
- Journal Title
  
  Molecular and Cellular Biology. 26(7)
  
  Pages: 2758-71
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13043003
[Journal Article] Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells2006
- Author(s)
  Lee T.I., Jenner R.G.., Boyer L.A., Guenther M.G.., Levine S.S., Kumar R.M., Chevalier B, Johnstone S.E., Cole M.F., Isono K, Koseki H, Fuchikami T, Abe K, Murray H.L.Zucker J.P., Yuan B, Bell G.W., Herbolsheimer E, Hannett N.M., Sun K, Odom D.T., Volkert T.L., Bartel D.P, Melton D.A., Gifford D.K., Jaenisch R, Young R.A.
- Journal Title
  
  Cell 125(2)
  
  Pages: 301-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13043003
[Journal Article] Distinct roles of Polycomb group gene products between transcriptionally repressed and active domains of Hoxb8.2006
- Author(s)
  Y.Fujimura, Isono, K, Vidal, M., Endoh, M., Kajita, H., Mizutani-Koseki, Y., Takihara, Y., van Lohuizen, M., Otte, A., Jenuwein, T., Deschamps, J., Koseki, H.
- Journal Title
  
  Development 133.12
  
  Pages: 2371-2381
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15200032
[Journal Article] Mammalian Polycomb-mediated repression of Hox genes requires the essential spliceosomal protein sf3b1.2005
- Author(s)
  Isono K, Mizutani-Koseki Y, Komori T, Schmidt-Zachmann M.S, Koseki H.
- Journal Title
  
  Gene Dev. 19(5)
  
  Pages: 536-41
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13043003
[Journal Article] Mammalian polyhomeotic homologues Phc2 and Phc 1 act in synergy to mediate Polycomb-repression of Hox genes.2005
- Author(s)
  Isono K, Fujimura Y, Shinga J, Yamaki M, 0-Wang J, Takihara Y, Murahashi Y, Takada Y, Mizutani-Koseki Y, Koseki H.
- Journal Title
  
  Molecular and Cellular Biology. 25(15)
  
  Pages: 6694-706
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13043003
[Journal Article] Polycomb-group proteins RinglA/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation.2004
- Author(s)
  Napoles M, Mermoud J, Wakao R, Tang Y.A, Endoh M, Appanah R, Nesterova T, Silva J, Otte A.P, Vidal M, KosekiH, Brockdorff N.
- Journal Title
  
  Dev. Cell 7(5)
  
  Pages: 663-76
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13043003
[Journal Article] Randomly inserted and targeted Hox/reporter fusions transcriptionally silenced in Polycomb mutants.2003
- Author(s)
  d Graaff W, Tomotsune D, Oosterveen T, Takihara Y, Koseki H, Deschamps J.
- Journal Title
  
  Pmc Natl Acad Sci U S A.1l 100(23)
  
  Pages: 13362-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13043003
[Journal Article] Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice.2002
- Author(s)
  Suzuki, M., Mizutani-Koseki, Y., Fujimura, Y., Miyagishima, H.Kaneko, T., Takada, Y., Akasaka, T., Tanzawa, H., Taldhara, Y., Nakano, M., Masumoto, H., Vidal, M., Isono K.Koseki, H.
- Journal Title
  
  Development 129
  
  Pages: 4171-4183
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13043003
[Journal Article] The role of Presenilin1 during somite segmentation.2001
- Author(s)
  Koizumi, K., Nakajima, M., Yuasa, S., Saga, Y., Sakai, T., Kuriyama, T., Shirasawa, T., Koseki,H.
- Journal Title
  
  Development 128
  
  Pages: 1391-1402
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13043003
[Journal Article] Mice doubly deficient for the Polycomb-Groupe genes Me118 and Bmil reveal synergy and requirement for maintenance but not initiation of Hox gene expression.2001
- Author(s)
  Akasaka, T., van Lohuizen, M.van der Lugt, N., Mizutani-Koseki, Y., Kanno, M., Taniguchi, M., Vidal, M., Alkema, M., Berns, A., Koseki,H.
- Journal Title
  
  Development. 128
  
  Pages: 1587-1597
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13043003
[Journal Article] Distinct roles of Polycomb group gene products between transcriptionally repressed and active domains of Hoxb8.2000
- Author(s)
  Fujimura Y, Isono K, Vidal M, Endoh M, Kajita H, Mizutani-Koseki Y, Takihara Y, van Lohuizen M, Otte A, Jenuwein T, Deschamps J, Koseki H
- Journal Title
  
  Development 133(12)
  
  Pages: 2371-2381
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13043003
[Patent] ES細胞の製造方法2011
- Inventor(s)
  古関明彦
- Industrial Property Rights Holder
  独立行政法人理化学研究所
- Filing Date
  2011-04-01
- Data Source
  KAKENHI-PLANNED-20062014
[Patent] ES細胞の製造方法2011
- Inventor(s)
  古関明彦
- Industrial Property Rights Holder
  独立行政法人理化学研究所
- Filing Date
  2011-04-01
- Overseas
- Data Source
  KAKENHI-PROJECT-20390088
[Patent] 変異体FGF2008
- Inventor(s)
  古関明彦
- Industrial Property Rights Holder
  国立大学法人千葉大学、独立行政法人理化学研究所
- Industrial Property Number
  2008-081826
- Filing Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-20390088
[Patent] 変異体FGF2008
- Inventor(s)
  古関明彦
- Industrial Property Rights Holder
  独立行政法人理化学研究所、国立大学法人千葉大学
- Industrial Property Number
  2008-081826
- Filing Date
  2008-03-26
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] ポリコム群による抑制ドメインの複製機構の解明2020
- Author(s)
  古関　明彦
- Organizer
  第１回新学術領域「非ゲノム情報複製」領域会議
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Proteasomal regulation of variant PCGF1-PRC1 contributes to activation of Polycomb target genes via self-ubiquitination2020
- Author(s)
  Haruhiko Koseki
- Organizer
  U Tokyo's LSBM Symposium 2020 in Hakone
- Data Source
  KAKENHI-PLANNED-19H05745
[Presentation] Polycomb in haematipoietic differentiation2020
- Author(s)
  古関　明彦
- Organizer
  The Chromatin and Epigenetics biweekly virtual seminar series, Tsinghua University
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Polycomb in haematipoietic differentiation2020
- Author(s)
  古関　明彦
- Organizer
  The Chromatin and Epigenetics biweekly virtual seminar series, Tsinghua University
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05745
[Presentation] ポリコム群による抑制ドメインの複製機構の解明2020
- Author(s)
  古関　明彦
- Organizer
  第１回新学術領域「非ゲノム情報複製」領域会議
- Data Source
  KAKENHI-PLANNED-19H05745
[Presentation] 哺乳類ポリコム群による発生過程の制御　Variant PRC1 in cellular differentiation2019
- Author(s)
  Haruhiko Koseki
- Organizer
  日本遺伝学会第91回大会
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Variant PRC1 in cellular differentiation2019
- Author(s)
  Haruhiko Koseki
- Organizer
  Friedrich Miescher Institute for Biomedical Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05745
[Presentation] Variant PRC1 in cellular differentiation2019
- Author(s)
  Haruhiko Koseki
- Organizer
  Keble College
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] ポリコム、分化、複製2019
- Author(s)
  Haruhiko Koseki
- Organizer
  新学術領域「多様かつ堅牢な細胞形質をさせる非ゲノム情報複製機構」第1回領域会議
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] 哺乳類ポリコム群による発生過程の制御　Variant PRC1 in cellular differentiation2019
- Author(s)
  Haruhiko Koseki
- Organizer
  日本遺伝学会第91回大会
- Data Source
  KAKENHI-PLANNED-19H05745
[Presentation] 疾患生物学：マウスからヒトへどう読み替えるか？2019
- Author(s)
  Haruhiko Koseki
- Organizer
  千葉大学消化器内科セミナー
- Invited
- Data Source
  KAKENHI-PLANNED-19H05745
[Presentation] Variant PRC1 in cellular differentiation2019
- Author(s)
  Haruhiko Koseki
- Organizer
  Friedrich Miescher Institute for Biomedical Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] ポリコム、分化、複製2019
- Author(s)
  Haruhiko Koseki
- Organizer
  新学術領域「多様かつ堅牢な細胞形質をさせる非ゲノム情報複製機構」第1回領域会議
- Data Source
  KAKENHI-PLANNED-19H05745
[Presentation] Variant PRC1 in cellular differentiation2019
- Author(s)
  Haruhiko Koseki
- Organizer
  Keble College
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05745
[Presentation] The role for enhancer of polycomb in chromatin replication and epigenetic inheritance2019
- Author(s)
  Haruhiko Koseki
- Organizer
  3rd RIKEN IMS-Stanford ISCBRM Joint Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Variant PCGF1-PRC1 is linked to proteasomal pathway to activate Polycomb target genes during development2019
- Author(s)
  Haruhiko Koseki
- Organizer
  Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Variant PCGF1-PRC1 is linked to proteasomal pathway to activate Polycomb target genes during development2019
- Author(s)
  Haruhiko Koseki
- Organizer
  Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05745
[Presentation] The role for enhancer of polycomb in chromatin replication and epigenetic inheritance2019
- Author(s)
  Haruhiko Koseki
- Organizer
  3rd RIKEN IMS-Stanford ISCBRM Joint Symposium
- Invited
- Data Source
  KAKENHI-PLANNED-19H05745
[Presentation] Polycomb in development2018
- Author(s)
  Haruhiko Koseki
- Organizer
  Shandong University School of Life ScienceJinan, China
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Functional analysis of DDX41 germline and somatic mutations in myeloid neoplasms.2018
- Author(s)
  Ayana Kon, June Takeda, Keisuke Kataoka, Kenichi Yoshida, Masahiro Marshall Nakagawa, Tetsuichi Yoshizato, Manabu Nakayama, Haruhiko Koseki, Hideki Makishima, Seishi Ogawa
- Organizer
  The 80th Annual Meeting of the Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-26221308
[Presentation] Variant PRC1 in gene activation and inactivation2018
- Author(s)
  Haruhiko Koseki
- Organizer
  Curie Institute
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Polycomb in development2018
- Author(s)
  Haruhiko Koseki
- Organizer
  Shandong University School of Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Functional analysis of DDX41 germline and somatic mutations in myeloid neoplasms.2018
- Author(s)
  Ayana Kon, June Takeda, Keisuke Kataoka, Kenichi Yoshida, Masahiro Marshall Nakagawa, Tetsuichi Yoshizato, Manabu Nakayama, Haruhiko Koseki, Hideki Makishima, Seishi Ogawa
- Organizer
  77th Anulal Meeeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-26221308
[Presentation] variant PRC1.1 in transcriptional phase transition2018
- Author(s)
  Haruhiko Koseki
- Organizer
  Friedrich Miescher Institute for Biomedical Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Polycomb in development2018
- Author(s)
  Haruhiko Koseki
- Organizer
  Cold Spring Harbor Asia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Stag2 regulates hematopoietic differentiation and self-renewal2018
- Author(s)
  Yotaro Ochi, Ayana Kon, Masahiro Marshall Nakagawa, Keisuke Kataoka, Kenichi Yoshida, Haruhiko Koseki, Manabu Nakayama, Akinori Yoda, Hideki Makishima, Akifumi Takaori-Kondo2, and Seishi Ogawa
- Organizer
  23rd Congress of European Hematology Association (EHA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221308
[Presentation] Induced activation of Polycomb-repressed　genes in mice2018
- Author(s)
  Haruhiko Koseki
- Organizer
  The European Molecular Biology Laboratory (EMBL)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Variant PRC1 in gene activation and inactivation2018
- Author(s)
  Haruhiko Koseki
- Organizer
  Keble College
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Meis2 activation by Kdm2b-containing complexesThe Babraham Institute2017
- Author(s)
  Koseki H
- Organizer
  The Babraham Institute
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Biological characterization of DDX41 germline and somatic mutations in myeloid neoplasms.2017
- Author(s)
  Ayana Kon, Keisuke Kataoka, Hideki Makishima, June Takeda, Tetsuichi Yoshizato, Masahiro Nakagawa, Yasunori Kogure, Kenichi Yoshida, Manabu Nakayama, Haruhiko Koseki, Seishi Ogawa
- Organizer
  日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19574
[Presentation] Gene regulation by Polycomb variants2017
- Author(s)
  Koseki H
- Organizer
  RIKEN-McGill Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Stag2 regulates Hematopoietic Differentiation and Self-Renewal2017
- Author(s)
  Yotaro Ochi, Ayana Kon, Kenichi Yoshida, Keisuke Kataoka, Masahiro Marshall Nakagawa, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Akifumi Takaori-Kondo, and Seishi Ogawa
- Organizer
  The 59th American Society of Hematology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221308
[Presentation] Cohesin subunit Stag2 regulates Hematopoietic Differentiation and Self-Renewal2017
- Author(s)
  Yotaro Ochi, Ayana Kon, Kenichi Yoshida, Keisuke Kataoka, Masahiro Marshall Nakagawa, Manabu Nakayama, Haruhiko Koseki, Akifumi Takaori-Kondo, and Seishi Ogawa
- Organizer
  The 79th Annual Meeting of the Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-26221308
[Presentation] Biological characterization of DDX41 germline and somatic mutations in myeloid neoplasms.2017
- Author(s)
  Ayana Kon, Keisuke Kataoka, June Takeda, Tetsuichi Yoshizato, Masahiro Nakagawa, Yasunori Kogure, Kenichi Yoshida, Manabu Nakayama, Haruhiko Koseki, Hideki Makishima, Seishi Ogawa
- Organizer
  日本癌学会総会
- Data Source
  KAKENHI-PROJECT-16K19574
[Presentation] Biological characterization of DDX41 germline and somatic mutations in myeloid neoplasms.2017
- Author(s)
  Ayana Kon, Keisuke Kataoka, Hideki Makishima, June Takeda, Tetsuichi Yoshizato, Masahiro Nakagawa, Yasunori Kogure, Kenichi Yoshida, Manabu Nakayama, Haruhiko Koseki, Seishi Ogawa
- Organizer
  The 79th Annual Meeting of the Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-26221308
[Presentation] Meis2 activation by Kdm2b-containing complexesOxford University2017
- Author(s)
  Koseki H
- Organizer
  Oxford University
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] 「iPS 細胞由来NKT 細胞によるがん治療技術の開発」 Development of adoptive immunotherapy for cancer using iPS-derived NKT cells2017
- Author(s)
  Koseki H
- Organizer
  第21回日本がん免疫学会総会 The 21st Annual Meeting of Japanese Association of Cancer Immunology
- Invited
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Meis2 regulation by Kdm2b complexes in developing midbrain2017
- Author(s)
  Koseki H
- Organizer
  Biotech Research & Innovation Centre (BRIC) University of Copenhagen
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Polycomb-mediated regulation of transition of transcriptional status2017
- Author(s)
  Koseki H
- Organizer
  第69回日本細胞生物学会大会 The 69th Annual Meeting of the Japan Sciety for Cell Biology
- Invited
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Clinical potential of iPS cell-derived invariant NKT cells2017
- Author(s)
  Koseki H
- Organizer
  Stanford ISCBRM-RIKEN IMS Joint Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Meis2 activation by Kdm2b-containing complexes2017
- Author(s)
  Koseki H
- Organizer
  Smurfit Institute of Genetics, Trinity College Dublin
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Activating Polycomb-repressed genes in mammals2017
- Author(s)
  Koseki H
- Organizer
  France-Japan Epigenetics Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Meis2 regulation by Kdm2b complexes in developing midbrain2017
- Author(s)
  Koseki H
- Organizer
  Friedrich Miescher Institute for Biomedical Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Cohesin subunit Stag2 regulates Hematopoietic Differentiation and Self-Renewal2017
- Author(s)
  Yotaro Ochi, Ayana Kon, Kenichi Yoshida, Keisuke Kataoka, Masahiro Marshall Nakagawa, Manabu Nakayama, Haruhiko Koseki, Akifumi Takaori-Kondo, and Seishi Ogawa
- Organizer
  The 76th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-26221308
[Presentation] Biological characterization of DDX41 germline and somatic mutations in myeloid neoplasms.2017
- Author(s)
  Ayana Kon, Keisuke Kataoka, June Takeda, Tetsuichi Yoshizato, Masahiro Nakagawa, Yasunori Kogure, Kenichi Yoshida, Manabu Nakayama, Haruhiko Koseki, Hideki Makishima, Seishi Ogawa
- Organizer
  The 76th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-26221308
[Presentation] PCGF6-PRC1 to suppress premature activation of meiosis/germ cell related genes in ES cells2016
- Author(s)
  古関　明彦
- Organizer
  Trinity College, Oxford University
- Place of Presentation
  Oxford, UK
- Year and Date
  2016-06-27
- Invited
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] The biological characterization of Srsf2 P95H mutation in the pathogenesis of myelodysplasia2016
- Author(s)
  Ayana Kon, Satoshi Yamazaki, Yusuke Shiozawa, Keisuke Kataoka, Yasunori Ota, Maiko Morita, Tetsuichi Yoshizato, Masashi Sanada, Kenichi Yoshida, Hideki Makisima, Yasuhito Nanya, Shinichi Kotani, June Takeda, Yosaku Watatani, Yotaro Ochi, Manabu Nakayama, Haruhiko Koseki, Hiromitsu Nakauchi, Seishi Ogawa
- Organizer
  The 78th Annual Meeting of the Japanese Society of Hematology
- Place of Presentation
  Yokohama, Kanagawa, Japan
- Data Source
  KAKENHI-PROJECT-16K19574
[Presentation] Protoracted NP95 binding to hemimethlated 1 DNA disrupts SETB1-mediated proviral silencing2016
- Author(s)
  古関明彦
- Organizer
  International Symposium on "Chromosome Orchestration System", Osaka University
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県淡路市）
- Year and Date
  2016-03-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] Regulation of promoter/enhancer interaction of Meis2 by KDM2B2016
- Author(s)
  古関　明彦
- Organizer
  Centro de investigaciones Biológicas (CSIC)
- Place of Presentation
  Madrid, Spain
- Year and Date
  2016-11-07
- Invited
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] The role of PRC1 variants during activation of Meis22016
- Author(s)
  古関　明彦
- Organizer
  Max-Planck Institute of Immunobiology and Epigenetics
- Place of Presentation
  Freiburg, Germany
- Year and Date
  2016-11-11
- Invited
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] PCGF6-PRC1 to suppress premature activation of meiosis/germ cell related genes in ES cells2016
- Author(s)
  古関　明彦
- Organizer
  Basel Stem Cell Network, Freidrich Miescher Institute
- Place of Presentation
  Basel, Switzerland
- Year and Date
  2016-06-23
- Invited
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] The biological characterization of Srsf2 P95H mutation in the pathogenesis of myelodysplasia2016
- Author(s)
  Ayana Kon, Satoshi Yamazaki, Yusuke Shiozawa, Keisuke Kataoka, Yasunori Ota, Maiko Morita, Tetsuichi Yoshizato, Masashi Sanada, Kenichi Yoshida, Hideki Makisima, Yasuhito Nanya, Shinichi Kotani, June Takeda, Yosaku Watatani, Yotaro Ochi, Manabu Nakayama, Haruhiko Koseki, Hiromitsu Nakauchi, Seishi Ogawa
- Organizer
  The 78th Annual Meeting of the Japanese Society of Hematology
- Place of Presentation
  Yokohama,Japan
- Data Source
  KAKENHI-PROJECT-26221308
[Presentation] 形態形成のエピジェネティック制御2016
- Author(s)
  古関　明彦
- Organizer
  秋田大学大学院医学系研究科・医学部
- Place of Presentation
  Madrid, Spain
- Year and Date
  2016-06-07
- Invited
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Polycomb in transcriptional phase transition of developmental genes2016
- Author(s)
  古関　明彦
- Organizer
  Mini Symposium, Genetic Control of Mouse embryonic Development at Hubrecht Institute
- Place of Presentation
  Utrecht, the Netherlands
- Year and Date
  2016-06-30
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02622
[Presentation] Protracted NP95 binding to hemimethylated DNA disrupts proviral silencing2015
- Author(s)
  古関明彦
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-04
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] 形態形成のエピジェネティック制御2015
- Author(s)
  古関明彦
- Organizer
  大阪大学蛋白質研究所セミナー　エピジェネティクス－分子機構から高次機能まで－
- Place of Presentation
  大阪大学蛋白質研究所1階講堂（大阪府吹田市）
- Year and Date
  2015-12-11
- Invited
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] Coordination of heterochromatin byNp95/Uhrf12014
- Author(s)
  Koseki H
- Organizer
  Seminar at University of Oxford
- Place of Presentation
  Oxford, UK
- Year and Date
  2014-09-23
- Invited
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] Activation of polycomb-repressed genes2014
- Author(s)
  Koseki H.
- Organizer
  Trinity College Seminar Series
- Place of Presentation
  Dublin, Ireland
- Invited
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] Activation of polycomb-repressed genes2014
- Author(s)
  Koseki H.
- Organizer
  Seminar at Ecole polytechnique federale de Lausanne
- Place of Presentation
  Lausanne, Switzerland
- Invited
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] Coordination of heterochromatin byNp95/Uhrf12014
- Author(s)
  Koseki H
- Organizer
  Seminar at MRC Clinical Sciences Centre, Imperial College London
- Place of Presentation
  London, UK
- Year and Date
  2014-09-22
- Invited
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] Coordination of heterochromatin byNp95/Uhrf12014
- Author(s)
  Koseki H
- Organizer
  Seminar at Biotech Research and Innovation Centre, University of Copenhagen
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2014-09-29
- Invited
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] iPS細胞技術を介したNKT細胞療法の開発2014
- Author(s)
  古関明彦
- Organizer
  第35回日本炎症・再生医学会シンポジウム6 「未来の再生医療」
- Place of Presentation
  沖縄県名護市　万国津梁館
- Year and Date
  2014-07-03
- Invited
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] Activation of polycomb-repressed genes2013
- Author(s)
  Koseki H.
- Organizer
  第42回日本免疫学会総会・学術集会
- Place of Presentation
  Chiba, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] Activation of polycomb-repressed genes2013
- Author(s)
  Koseki H.
- Organizer
  Mouse Molecular Genetics Conference
- Place of Presentation
  Cambridge, UK
- Invited
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] DNA methylation in T cells and gut immune homeostasis2013
- Author(s)
  Koseki H.
- Organizer
  3rd McGill-RIKEN Workshop
- Place of Presentation
  Montreal, Canada
- Invited
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] Polycomb potentiates Meis2 activation in midbrain by mediating precursory interaction of promoter with tissue-specific enhance2013
- Author(s)
  古関明彦
- Organizer
  RCAI-Michigan Joint Workshop
- Place of Presentation
  米国、アナーバー
- Year and Date
  2013-01-16
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] Epigetic regulation of spermiogenesis2013
- Author(s)
  Koseki H.
- Organizer
  The 10th Annual Meeting of Asian Reproductive Biotechnology Society
- Place of Presentation
  Phan Thiet, Vietnam
- Invited
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] Polycomb potentiates Meis2 activation in midbrain by mediating precursory interaction of promoter with tissue-specific enhance2013
- Author(s)
  Koseki H
- Organizer
  RCAI-Michigan Joint Workshop
- Place of Presentation
  米国、アナーバー(招待講演)
- Year and Date
  2013-01-16
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] Mechanisms underlying Polycomb repression2012
- Author(s)
  Koseki H
- Organizer
  文部科学省新学術領域「細胞運命制御」
- Place of Presentation
  日本、京都(招待講演)
- Year and Date
  2012-11-06
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] Mechanisms underlying Polycomb repression2012
- Author(s)
  古関明彦
- Organizer
  文部科学省新学術領域細胞運命制御
- Place of Presentation
  日本、京都
- Year and Date
  2012-11-06
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] ポリコーム群Ring1A/BによるヒストンH2Aユビキチン化のES細胞における局在と役割2012
- Author(s)
  遠藤充浩、遠藤高帆、磯野協一、古関明彦
- Organizer
  第6回エピジェネティクス研究会
- Place of Presentation
  東京一ツ橋学術総合センター
- Data Source
  KAKENHI-PROJECT-21602006
[Presentation] ポリコム群の機能発現メカニズム2012
- Author(s)
  Koseki H
- Organizer
  第4回シグナルネットワーク研究会
- Place of Presentation
  日本、大阪(招待講演)
- Year and Date
  2012-05-18
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] ポリコム群の機能発現メカニズム2012
- Author(s)
  古関明彦
- Organizer
  第4回シグナルネットワーク研究会
- Place of Presentation
  日本、大阪
- Year and Date
  2012-05-18
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] Temporal Regulation of Cortical Neural Precursor Cell Fate by Polycomb Group Proteins2011
- Author(s)
  Yusuke Hirabayashi, Nao Suzki, Masafumi Tsuboi, Miguel Vidal, Haruhiko Koseki, Yukiko Gotoh
- Organizer
  CDB Symposium 2011
- Place of Presentation
  理化学研究所発生・再生科学総合研究センター(神戸市)
- Year and Date
  2011-03-15
- Data Source
  KAKENHI-PROJECT-21770231
[Presentation] Application of iPS Cell Technology for NKT Cell-targeted Adjuvant Therapy for Tumors in Mice2011
- Author(s)
  Koseki H
- Organizer
  14th US-Japan Cellular and Gene Therapy Confe rence
- Place of Presentation
  米国、ベセスダ
- Year and Date
  2011-02-24
- Invited
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] SAM domain-mediated polymerization of mammalian polyhomeotic homologues mediates recruitment of PRC1 to Polycomb target genes and their condensation2011
- Author(s)
  古関明彦
- Organizer
  3rd X-inactivation meeting
- Place of Presentation
  英国、オックスフォード
- Year and Date
  2011-07-23
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] SAM domain-mediated polymerization of mammalian polyhomeotic homologues mediates recruitment of PRC1 to Polycomb target genes and their condensation2011
- Author(s)
  Koseki H
- Organizer
  3rd X-inactivation meeting
- Place of Presentation
  英国、オックスフォード(招待講演)
- Year and Date
  2011-07-23
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] H2A ubiquitination is an essential step to mediate PRC1 Polycomb silencing of differentiation genes in ES cells2011
- Author(s)
  Endoh M and Koseki H
- Organizer
  第9回幹細胞シンポジウム
- Place of Presentation
  泉ガーデンギャラリー、東京
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-21602006
[Presentation] Polycomb-dependent regulation for differentiation programs of stem cells and progenitors2011
- Author(s)
  Koseki H
- Organizer
  アジアエピゲノムワークショップ/第五回日本エピジェネティクス研究会
- Place of Presentation
  日本、熊本市(招待講演)
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] Temporal regulation of cortical neural precursor cell fate by polycomb group proteins2011
- Author(s)
  Yusuke Hirabayashi, Nao Suzki, Masafumi Tsuboi, Miguel Vidal, Haruhiko Koseki, Yukiko Gotoh
- Organizer
  CDB Symposium
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21770231
[Presentation] SAM domain-mediated polymerization of mammalian polyhomeotic homologues mediates recruitment of PRC1 to Polycomb target genes and their condensation2011
- Author(s)
  Koseki H
- Organizer
  3rd X-inactivation meeting
- Place of Presentation
  英国、オックスフォード(招待講演)
- Year and Date
  2011-07-23
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] Application of iPS Cell Technology for NKT Cell-targeted Adjuvant Therapy for Tumors in Mice2011
- Author(s)
  Koseki H
- Organizer
  14th US-Japan Cellular and Gene Therapy Conference
- Place of Presentation
  米国、ベセスダ(招待講演)
- Year and Date
  2011-02-24
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] Polycomb-dependent regulation for differentiation programs of stem cells and progenitors2011
- Author(s)
  Koseki H
- Organizer
  アジアエピゲノムワークショップ/第五回日本エピジェネティクス研究会
- Place of Presentation
  日本、熊本市(招待講演)
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] Polycomb-dependent regulation for differentiation programs of stem cells and progenitors2011
- Author(s)
  古関明彦
- Organizer
  アジアエピゲノムワークショップ/ 第五回日本エピジェネティクス研究会
- Place of Presentation
  日本、熊本市
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] ユビキチン化ヒストンH2AのES細胞における局在と役割2011
- Author(s)
  遠藤充浩、遠藤高帆、磯野協一、古関明彦
- Organizer
  第5回エピジェネティクス研究会
- Place of Presentation
  KKRホテル熊本
- Data Source
  KAKENHI-PROJECT-21602006
[Presentation] 遺伝現象におけるエピジェネティック制御とリプログラミング2010
- Author(s)
  Koseki H
- Organizer
  第62回日本細胞生物学会大会
- Place of Presentation
  日本、大阪市
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-20390088
[Presentation] 遺伝現象におけるエピジェネティック制御とリプログラミング2010
- Author(s)
  Koseki H
- Organizer
  第62回日本細胞生物学会大会
- Place of Presentation
  大阪,日本
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-20390088
[Presentation] Temporal regulation of cortical neural precursor cell fate by polycomb group proteins2010
- Author(s)
  Yusuke Hirabayashi, Nao Suzki, Masafumi Tsuboi, Miguel Vidal, Haruhiko Koseki, Yukiko Gotoh
- Organizer
  Keystone Symposium-Dynamics of Eukaryotic Transcription during Development
- Place of Presentation
  BIg Sky, USA
- Year and Date
  2010-04-08
- Data Source
  KAKENHI-PROJECT-21770231
[Presentation] The role of Polycomb body to mediate Hox repression2010
- Author(s)
  Koseki H
- Organizer
  東京大学分子細胞生物学研究所核内情報研究分野シンポジウム
- Place of Presentation
  日本、東京都
- Year and Date
  2010-11-02
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] 遺伝現象におけるエピジェネティック制御とリプログラミング2010
- Author(s)
  古関明彦
- Organizer
  第62回日本細胞生物学会大会
- Place of Presentation
  日本、大阪市
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] The role of Polycomb body to mediate Hox repression2010
- Author(s)
  Koseki H
- Organizer
  東京大学分子細胞生物学研究所核内情報研究分野シンポジウム
- Place of Presentation
  東京、日本
- Year and Date
  2010-11-02
- Data Source
  KAKENHI-PROJECT-20390088
[Presentation] Polycomb-dependent regulation for differentiation programs of stem cells and progenitors2010
- Author(s)
  古関明彦
- Organizer
  第16回国際分化学会国際会議
- Place of Presentation
  日本、奈良市
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] プロモーターアレイを用いたポリコーム群によるES細胞維持メカニズムの解析2010
- Author(s)
  Koseki H
- Organizer
  日本エピジェネティクス研究会第4回年会
- Place of Presentation
  日本、米子市
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] プロモーターアレイを用いたポリコーム群によるES細胞維持メカニズムの解析2010
- Author(s)
  Koseki H
- Organizer
  日本エピジェネティクス研究会第4回年会
- Place of Presentation
  米子,日本
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-20390088
[Presentation] Temporal regulation of cortical neural precursor cell fate by polycomb group proteins2010
- Author(s)
  Yusuke Hirabayashi, Nao Suzki, Masafumi Tsuboi, Miguel Vidal, Haruhiko Koseki, Yukiko Gotoh
- Organizer
  Minisymposium on Developmental Neurobiology
- Place of Presentation
  San Diego, CA
- Data Source
  KAKENHI-PROJECT-21770231
[Presentation] プロモーターアレイを用いたポリコーム群によるES細胞維持メカニズムの解析2010
- Author(s)
  Koseki H
- Organizer
  日本エピジェネティクス研究会第4回年会
- Place of Presentation
  日本、米子市
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-20390088
[Presentation] Temporal regulation of cortical neural precursor cell fate by polycomb group proteins2010
- Author(s)
  Yusuke Hirabayashi, Nao Suzki, Masafumi Tsuboi, Miguel Vidal, Haruhiko Koseki, Yukiko Gotoh
- Organizer
  2nd German-Japanese Neurogenesis Meeting 2010
- Place of Presentation
  Spreewald, Germany
- Data Source
  KAKENHI-PROJECT-21770231
[Presentation] The role of Polycomb body to mediate Hox repression2010
- Author(s)
  Koseki H
- Organizer
  東京大学分子細胞生物学研究所核内情報研究分野
- Place of Presentation
  日本、東京都(シンポジウム)
- Year and Date
  2010-11-02
- Data Source
  KAKENHI-PROJECT-20390088
[Presentation] The role of Polycomb body to mediate Hox repression2010
- Author(s)
  古関明彦
- Organizer
  東京大学分子細胞生物学研究所核内情報研究分野シンポジウム
- Place of Presentation
  日本、東京都
- Year and Date
  2010-11-02
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] Polycomb temporally regulates trophoblast development by promoting stem cell differentiation2010
- Author(s)
  Endoh M, Endo TA, and Koseki H
- Organizer
  第8回幹細胞シンポジウム
- Place of Presentation
  淡路夢舞台国際会議場
- Data Source
  KAKENHI-PROJECT-21602006
[Presentation] ポリコーム群とコアな転写因子のクロストークによる栄養芽幹細胞の分化制御2010
- Author(s)
  遠藤充浩、遠藤高帆、古関明彦
- Organizer
  第4回日本エピジェネティクス研究会
- Place of Presentation
  米子市文化ホール
- Data Source
  KAKENHI-PROJECT-21602006
[Presentation] ポリコーム群は転写因子の抑制を介して栄養芽幹細胞の分化を促進する2010
- Author(s)
  遠藤充浩、遠藤高帆、古関明彦
- Organizer
  第43回日本発生生物学会
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-21602006
[Presentation] Polycomb-dependent regulation for differentiation programs of stem cells and progenitors2010
- Author(s)
  Koseki H
- Organizer
  第16回国際分化学会国際会議
- Place of Presentation
  奈良、日本
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-20390088
[Presentation] Polycomb-dependent regulation for differentiation programs of stem cells and progenitors2010
- Author(s)
  Koseki H
- Organizer
  第16回国際分化学会国際会議
- Place of Presentation
  日本、奈良市
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-20390088
[Presentation] ポリコーム群タンパク質による大脳皮質神経系前駆細胞の分化運命制御2009
- Author(s)
  平林祐介、鈴木菜央、壷井將史、Miguel Vidal, 古関明彦, 後藤由季子
- Organizer
  第82回日本生化学会大会(口頭発表)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21770231
[Presentation] PRC1 suppresses ES cell differentiation programs through PRC2-dependent and PRC2-independent mechanisms2009
- Author(s)
  遠藤充浩、遠藤高帆、古関明彦
- Organizer
  第19回日本数理生物学会年会
- Place of Presentation
  東京大学駒場キャンパス
- Data Source
  KAKENHI-PROJECT-21602006
[Presentation] Temporal regulation of cortical neural precursor cell fate by polycomb group proteins2009
- Author(s)
  Yusuke Hirabayashi, Nao Suzki, Masafumi Tsuboi, Miguel Vidal, Haruhiko Koseki, Yukiko Gotoh
- Organizer
  EuroEpiStem--2009 Meeting
- Place of Presentation
  Cambridge, UK
- Data Source
  KAKENHI-PROJECT-21770231
[Presentation] ポリコーム群タンパク質による大脳皮質神経系前駆細胞の分化運命制御2009
- Author(s)
  Yusuke Hirabayashi, Nao Suzki, Masafumi Tsuboi, Miguel Vidal, Haruhiko Koseki, Yukiko Gotoh
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21770231
[Presentation] ES細胞におけるポリコーム群の動き2009
- Author(s)
  Koseki H
- Organizer
  第42回日本発生生物学会年会
- Place of Presentation
  京都、日本
- Year and Date
  2009-05-29
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] PRC1 suppresses ES cell differentiation programs through PRC2-dependent and PRC2-independent mechanisms2009
- Author(s)
  Endoh M, Endo TA, Endoh T, Vidal M, and Koseki H
- Organizer
  Cold Spring Harbor Laboratory Meeting
- Place of Presentation
  Cambridge, UK
- Data Source
  KAKENHI-PROJECT-21602006
[Presentation] HP1g links histone H3K9 methylation to homologus chromosome pairing during melotic prophase2009
- Author(s)
  Koseki H
- Organizer
  he Epigenetics 2009 Australian Scientific Conference@Epigenetics and Development
- Place of Presentation
  Brisbane, Australia
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20390088
[Presentation] ES細胞におけるポリコーム群の動き2009
- Author(s)
  Koseki H
- Organizer
  第42回日本発生生物学会年会
- Place of Presentation
  京都、日本
- Year and Date
  2009-05-29
- Data Source
  KAKENHI-PROJECT-20390088
[Presentation] HP1g links histone H3K9 methylation to homologus chromosome pairing during melotic prophase2009
- Author(s)
  古関明彦
- Organizer
  The Epigenetics 2009 Australian Scientific Conference@Epigenetics and Development
- Place of Presentation
  オーストラリア、ブリスベン
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] ポリコーム群Ring1A/Bによるヒストン修飾を介した幹細胞制御2009
- Author(s)
  遠藤充浩、遠藤高帆、古関明彦
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-21602006
[Presentation] Temporal regulation of cortical neural precursor cell fate by polycomb group proteins2009
- Author(s)
  Yusuke Hirabayashi, Nao Suzki, Masafumi Tsuboi, Miguel Vidal, Haruhiko Koseki, Yukiko Gotoh
- Organizer
  EuroEpiStem-2009 Meeting
- Place of Presentation
  Cambridge, UK
- Year and Date
  2009-11-04
- Data Source
  KAKENHI-PROJECT-21770231
[Presentation] Temporal regulation of cortical neural precursor cell fate by polycomb group proteins2009
- Author(s)
  Yusuke Hirabayashi, Nao Suzki, Masafumi Tsuboi, Miguel Vidal, Haruhiko Koseki, Yukiko Gotoh
- Organizer
  ISSCR 8th Annual Meeting
- Place of Presentation
  (Barcelona, Spain) Poster presentation
- Data Source
  KAKENHI-PROJECT-21770231
[Presentation] ポリコーム群Ring1A/Bによるヒストン修飾を介した幹細胞制御2009
- Author(s)
  遠藤充浩、遠藤高帆、古関明彦
- Organizer
  第3回日本エピジェネティクス研究会年会
- Place of Presentation
  東京一ツ橋学術総合センター
- Data Source
  KAKENHI-PROJECT-21602006
[Presentation] Roles of Polycomb group proteins Ring1A/B in mouse ES cells and TS cells2009
- Author(s)
  遠藤充浩、古関明彦
- Organizer
  第7回幹細胞シンポジウム
- Place of Presentation
  学術総合センター
- Data Source
  KAKENHI-PROJECT-21602006
[Presentation] ES細胞におけるポリコーム群の動き2009
- Author(s)
  古関明彦
- Organizer
  第42回日本発生生物学会年会
- Place of Presentation
  日本、京都
- Year and Date
  2009-05-29
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition2009
- Author(s)
  Yusuke Hirabayashi, Nao Suzki, Masafumi Tsuboi, Miguel Vidal, Haruhiko Koseki, Yukiko Gotoh
- Organizer
  Keystone Symposia-Chromatin Dynamics and Higher Order Organization
- Place of Presentation
  (Coeurd'Alene, ID) Poster presentation
- Data Source
  KAKENHI-PROJECT-21770231
[Presentation] HP1g links histone H3K9 methylation to homologus chromosome pairing during melotic prophase2009
- Author(s)
  Koseki H
- Organizer
  The Epigenetics 2009 Australian Scientific Conference@Epigenetics and Development
- Place of Presentation
  ブリスベン、豪州
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] HP1g links histone H3K9 methylation to homologus chromosome pairing during melotic prophase2009
- Author(s)
  Koseki H
- Organizer
  The Epigenetics 2009 Australian Scientific Conference@Epigenetics and Development
- Place of Presentation
  ブリスベン、豪州
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20390088
[Presentation] Temporal regulation of cortical neural precursor cell fate by polycomb group proteins2009
- Author(s)
  Yusuke Hirabayashi, Nao Suzki, Masafumi Tsuboi, Miguel Vidal, Haruhiko Koseki, Yukiko Gotoh
- Organizer
  ISSCR 8th Annual Meeting
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2009-07-09
- Data Source
  KAKENHI-PROJECT-21770231
[Presentation] Polycom repression mediates mediates pluripotency of ES cells2008
- Author(s)
  Koseki H
- Organizer
  Cold Spring Harbor Laboratory,
- Place of Presentation
  New York, U.S.A
- Year and Date
  2008-10-31
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] Mouse development: embryogenesis2008
- Author(s)
  古関明彦
- Organizer
  EMBO Practical Course on Anatomy and Embryology of the Mouse
- Place of Presentation
  クロアチア、ザグレブ
- Year and Date
  2008-09-06
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] Histone H2A ubiquitinylation subdivides bivalent genes into PRC1-dependent and independent domains in ES cells2008
- Author(s)
  Koseki H
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会、合同大会
- Place of Presentation
  神戸, 日本
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] Polycom repression mediates pluripotency of ES cells2008
- Author(s)
  古関明彦
- Organizer
  Cold Spring Harbor Laboratory
- Place of Presentation
  アメリカ、ニューヨーク
- Year and Date
  2008-10-31
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] Polycom repression mediates pluripotency of ES cells2008
- Author(s)
  Koseki H
- Organizer
  Cold Spring Harbor Laboratory
- Place of Presentation
  New York, U.S.A.
- Year and Date
  2008-10-31
- Data Source
  KAKENHI-PROJECT-20390088
[Presentation] Mouse development : embryogenesis2008
- Author(s)
  Koseki H
- Organizer
  EMBO Practical Course on Anatomy and Embryology of the Mouse
- Place of Presentation
  Zagreb, Croatia
- Year and Date
  2008-09-06
- Data Source
  KAKENHI-PROJECT-20390088
[Presentation] Histone H2A ubiquitinylation subdivides bivalent genes into PRC1-dependent and -independent domains in ES cells2008
- Author(s)
  Koseki H
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会、合同大会
- Place of Presentation
  神戸,日本
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-20390088
[Presentation] Polycomb group proteins Ring1A/B are functionally linked to the coretranscriptional regulatory circuitry to maintain ES cell identity2008
- Author(s)
  Koseki H
- Organizer
  Shanghai Cancer Institute
- Place of Presentation
  Shanghai, China
- Year and Date
  2008-07-03
- Data Source
  KAKENHI-PROJECT-20390088
[Presentation] Histone H2A ubiquitinylation subdivides bivalent genes into PRC1-dependent and-independent domains in ES cells2008
- Author(s)
  Koseki H
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会、合同大会
- Place of Presentation
  神戸,日本
- Data Source
  KAKENHI-PROJECT-20390088
[Presentation] Polycomb group proteins Ring1A/B are functionally linked to the coretranscriptional regulatory circuitry to maintain ES cell identity2008
- Author(s)
  Koseki H
- Organizer
  Shanghai Cancer Institute
- Place of Presentation
  Shanghai, China
- Year and Date
  2008-07-03
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] Histone H2A ubiquitinylation subdivides bivalent genes into PRC1-dependent and -independent domains in ES cells2008
- Author(s)
  古関明彦
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会、合同大会
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] Mouse development : embryogenesis2008
- Author(s)
  Koseki H
- Organizer
  EMBO Practical Course on Anatomy and Embryology of the Mouse
- Place of Presentation
  Zagreb, Croatia
- Year and Date
  2008-09-06
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] Polycomb group proteins Ring1A/B are functionally linked to the coretranscriptional regulatory circuitry to maintain ES cell identity2008
- Author(s)
  古関明彦
- Organizer
  Shanghai Cancer Institute
- Place of Presentation
  中国、上海
- Year and Date
  2008-07-03
- Data Source
  KAKENHI-PLANNED-20062014
[Presentation] 精子形成過程におけるポリコームScmh1の機能解析2007
- Author(s)
  高田幸、古関明彦
- Organizer
  第40回日本発生生物学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-18051019
[Presentation] Np95/UHRF1を介したエピジェネチック制御メカニズム
- Author(s)
  古関明彦
- Organizer
  福島医学会学術研究集会シンポジウム
- Place of Presentation
  福島
- Invited
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] ポリコム群抑制ドメイン形成メカニズム
- Author(s)
  古関明彦
- Organizer
  国立遺伝学研究所研究会2012/2012 Research Conference of National Institute of Genetics
- Place of Presentation
  静岡
- Invited
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] ポリコム群の機能発現メカニズム
- Author(s)
  古関明彦
- Organizer
  第4回シグナルネットワーク研究会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] Polycomb potentiates Meis2 activation in midbrain by mediating precursory interaction of promoter with tissue-specific enhancer
- Author(s)
  古関明彦
- Organizer
  RCAI-Michigan Joint Workshop
- Place of Presentation
  米国ミシガン州
- Invited
- Data Source
  KAKENHI-PROJECT-23249015
[Presentation] Mechanisms underlying Polycomb repression
- Author(s)
  古関明彦
- Organizer
  文部科学省新学術領域「細胞運命制御」
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-23249015

1. AOE Tomohiko (90311612)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. TANIGUCHI Masaru (80110310)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. MITSUHIRO Endoh (40391883)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
4. NAKAYAMA MANABU (30370927)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
5. YASUDA Kunio (30025473)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TAKADA Yuki (40392013)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. TAKAHO Endoh (40384862)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
8. OGAWA SEISHI (60292900)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
9. KAMADA Hiroshi (00169608)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. SASAZUKI Takehiko (50014121)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. KISHIMOTO Tadamitsu (10093402)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. OKUMURA Ko (50009700)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. SHIMADA Kazuo (70196476)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. HORINOUCHI Sueharu (80143410)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. SHIMURA Yoshiro (60025426)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. YAMADA Yasuyuki (50026415)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. KARUBE Isao (50089827)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. BEPPU Teruhiko (80011873)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. KIKUTANI Hitoshi (80161412)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. SAITO Takashi (50205655)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. WATANABE Takeshi (40028684)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
22. KANNO Masamoto (40161393)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
23. 岡田誠治 (50282455)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
24. 幡野雅彦 (20208523)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
25. 徳久剛史 (20134364)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
26. 湯浅茂樹 (70127596)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
27. SHIBAHARA Kei-ichi (20263098)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. JUN Shinga (20334211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. FUJIMURA Yu-Ichi (60392099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
30. SOEJIMA Hidenobu (30304885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
31. JOH Keiichiro (90124809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. HIGASHIMOTO Ken (30346887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
33. KUGOH Hiroyuki (40225131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. HIRABAYASHI Yusuke (80447391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
35. GOTOH Yukiko (70252525)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
36. KYO Masaharu (70195395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. WATANABE Masao (90240522)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. OKADA Kiyotaka (50101093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. KOMEDA Yoshifumi (10124215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. KATO Koichi (20211849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. MURAKAMI Yuji (70272995)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. YOSHIDA Minoru (80191617)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. ISOGAI Akira (20011992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. WAKASUGI Hiro (10112632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. SHINOZAKI Kazuo (20124216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. FUJII Tadashi (20011611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. YAMADA Tetsuji (00191320)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. DOKE Noriyuki (80023472)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. TANAKA Keiji (10108871)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. SAKAI Shingo (60033388)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. URANO Naoto (90262336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. MATSUBARA Ken-ichi (20037394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
53. ADACHI Emiko (60009496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
54. MIZOTA Atsushi (10239262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
55. SANO Nobuaki (80196302)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
56. KUZUYAMA Tomohisa (30280952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
57. YOKOYAMA Kenji (80242121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
58. KAMII Takehiko (90262708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
59. SHIRASAWA Hiroshi (00216194)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
60. ISHIDA Atsushi (70334183)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
61. MIYAZAKI Masaru (70166156)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
62. GONDO Yoichi (40225678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
63. AIBA Atsu (20271116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
64. UENO Naoto (40221105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
65. KOMINAMI Ryo (40133615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
66. NISHIDA Keigo (80360618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
67. Kon Ayana (20772403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
68. 高橋淑子 (10183857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
69. 赤坂甲治 (60150968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
70. 相賀裕美子 (50221271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
71. 倉谷滋 (00178089)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
72. 高田慎治 (60206753)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
73. 赤坂武 (40311609)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
74. 磯野協一 (90323435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
75. 鈴木盛一 (00111386)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
76. 絵野沢伸 (40232962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
77. 梨井康 (60321890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
78. 中世古幸信 (30231468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
79. 原田宏 (90015991)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
80. 鈴木正康 (70226554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
81. 長田重一 (70114428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
82. 菅村和夫 (20117360)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
83. 西川伸一 (60127115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
84. 平野俊夫 (40136718)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
85. 木下タロウ (10153165)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
86. 勝木元也 (20051732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
87. 荒田洋治 (40011499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
88. 中村祐輔 (70217909)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
89. 河原井昌裕 (60234142)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
90. 早出広司 (10187883)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
91. 野村港二 (00183905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
92. 大野睦人 (80201979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
93. 小林悟 (90225508)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
94. 志田壽利 (00144395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
95. 坂本博 (00187048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
96. 横山茂之 (00159229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
97. 井上丹 (40114855)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
98. 高網陽子 (60261913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
99. 村山耕一郎 (00219891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
100. 本庶佑 (80090504)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
101. 坂口志文 (30280770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
102. 阪口薫雄 (70192086)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
103. 清野宏 (10271032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
104. 阿部訓也 (40240915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
105. 山田源 (80174712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
106. 菅原稔 (20311558)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
107. YATSUKI Hitomi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
108. Sanada Masashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
109. Sato Aiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
110. Makishima Hideki

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
111. Kataoka Keisuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
112. Miyazaki Yasushi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
113. Chiba Shigeru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
114. Nakao Shinji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
115. Nakauchi Hiromitsu

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
116. OHARA Osamu

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
117. 小原収

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
118. 奥山虎之

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
119. 藤野真之

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
120. マリセン B.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
121. バーリング R.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
122. マティス D.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
123. ベノワ C.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
124. クーパー J.A.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
125. ハーガン I.M.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
126. ラジャウスキー K.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
127. シラー F.W.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
128. デュマ C.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
129. ツジイ F.I.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
130. ロバーツ G.C.K.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
131. デルセニー M.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
132. フォルセン K.S.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
133. TSUJI Federick

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
134. FORSEN Karl

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
135. COOPER Jonathan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
136. HAGAN Iain

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
137. ROBERTS Gordon

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
138. NAKASEKO Nobuyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
139. DUMAS C.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
140. SCHELLER Frieder

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
141. DELSENY Michel

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
142. MATHIS Diane

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
143. BENOIST Christophe

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
144. MALISSEN Bernard

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
145. BALLING Rudolf

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
146. RAJEWSKY Klaus

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
147. 和田雅人

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
148. スレイマン C.W.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
149. ラスキー R.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
150. シュミット R.D.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
151. マリッセン B.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
152. MATHIS D.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
153. BENOIST C

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
154. PIATIGORSKY ジェイ

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
155. MARTY J.L.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
156. THOMPSON C.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
157. GOSSLER A

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
158. KANEKO Shin

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
159. MASUI Osamu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
160. OHSHIMA Motohiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
161. HISHIKAWA Yoshitaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
162. NARAZAKI Masashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
163. OGATA Tsutomu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
164. MATSUBARA Keiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
165. UNOKI Motoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
166. KANKI Yasuharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
167. HARADA Yuka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
168. KANEDA Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
169. NANYA Yasuhito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
170. Kawamoto Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
171. LI Yuanyuan

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
172. ITO Chizuru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
173. IKAWA Tomokatsu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
174. FURUSAWA Yukihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
175. OKADA Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
176. TSUMURA Miyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
177. FUJII Shinーichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
178. TAKENOBU Hisanori

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
179. SHIMADA Midori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
180. NAKAI Yuji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
181. KOBAYASHI Hisato

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
182. HAYASHI Yohei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
183. NAKATO Ryuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
184. BABA Yoshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
185. FUKUDA Sanae

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
186. OSAWA Mitsujiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
187. HIRAOKA Shuichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
188. TAMAMURA Yoshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
189. MAENOHARA Shoji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
190. TAKAYAMA Kenichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
191. 植村靖史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
192. 江藤浩之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
193. 高山直也

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
194. 伊藤伸介

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
195. 須田年生

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
196. 増子正義

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
197. 岩間厚志

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
198. 青山和正

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
199. 中山俊憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
200. 木内政宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
201. 平原潔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
202. 小野寺淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
203. 深谷知宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
204. 高木秀明

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
205. 佐藤克明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
206. チョウジョウフナランツオツク

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
207. 山崎聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
208. 田中伸弥

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
209. 伊勢渉

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
210. 近藤隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
211. 大塚泰史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
212. 藤泰子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
213. 南敬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
214. 油谷浩幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
215. 中尾光善

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
216. 原田浩徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
217. 小出周平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
218. 田中知明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
219. 下田和哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
220. 宮城聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
221. 米谷耕平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
222. 松井啓隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
223. 稲葉俊哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
224. 日下部学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
225. 末原泰人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
226. 篠原隆司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
227. 大日向康秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
228. 中西真

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
229. 有田恭平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
230. 西山敦哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
231. 中西圭子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
232. 北嶋修司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
233. 松久葉一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
234. 黒崎知博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
235. 縣保年

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
236. 増田喬子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
237. 吉田松生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
238. 山下暁朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
239. 青田聖恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
240. 大保和之

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
241. 中島やえ子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
242. 尾崎俊文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
243. 市川美紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
244. 中川原章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
245. 中村洋子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
246. 岸雄介

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
247. 浦西洸介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
248. 望月研太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
249. 鈴木歩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
250. 奥田晶彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
251. 年森清隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
252. 高松絵美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
253. 藥師寺那由他

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
254. 舛本寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
255. 堀昌平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
256. 田嶋正二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
257. 河村由紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
258. 谷内一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
259. 井上梓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
260. 小塚智沙代

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
261. 佐藤尚子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
262. 小林正夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
263. 清水佳奈子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
264. Jesmin Akter

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
265. 松田泰斗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
266. 村尾直哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
267. 岡崎孝映

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
268. 佐々木裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
269. SHARIF JAFAR

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
270. 立花誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
271. 藤木克則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
272. 久保允人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
273. 仲野徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
274. 伊藤敬

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
275. 岩倉洋一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
276. Li Youxian

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
277. 本田賢也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
278. 有田誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
279. 片岡洋祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
280. 坂本啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
281. 山口朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
282. 勝部憲一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
283. 吉田健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
284. 富澤信一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
285. 尾野道男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
286. 横手幸太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
287. 宮本圭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
288. 伊川正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
289. 井上聰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
290. 今村優子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Koseki Haruhiko 古関 明彦

KOSEKI Haruhiko 古関 明彦

古関 明彦 コセキ ハルヒコ

Research Projects

Research Products

Co-Researchers

ポリコム群による抑制ドメインの複製機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Towards understanding the role for DNMT1 to establish Polycomb-mediated gene silencingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of CpG dinucleotides to generate PcG-repressive genomic domainsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Epigenetic regulation of mammalian spermatogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Dissecting molecular mechanisms mediated by Polycomb group proteins in maintenance and differentiation of ES cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Koseki Haruhiko 古関明彦

KOSEKI Haruhiko 古関明彦

古関明彦コセキハルヒコ