Nakayama Manabu 中山学

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NAKAYAMA Manabu 中山学

NAKAYAMA MANABU 中山学

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Researcher Number	30370927
Other IDs
Affiliation (Current)	2022: 公益財団法人かずさDNA研究所, 先端研究開発部, 主任研究員
Affiliation (based on the past Project Information) *help	2017 – 2021: 公益財団法人かずさDNA研究所, 先端研究開発部, 主任研究員 2016 – 2017: 公益財団法人かずさDNA研究所, 技術開発研究部, チーム長 2014: 公益財団法人かずさDNA研究所, 技術開発研究部, チーム長 2013: 公益財団法人かずさＤＮＡ研究所, ヒトゲノム研究部, 主任研究員 2012: 公益財団法人かずさDMA研究所, ヒトゲノム研究部, 主任研究員 … More 2009 – 2010: Kazusa DNA Research Institute, ヒトゲノム研究部・ヒト遺伝子応用技術研究室, 主任研究員 2008: Kazusa DNA Research Institute, ヒトゲノム研究部・ゲノム解析技術研究室, 主任研究員 2007: Kazusa DNA Research Institute, Department of Human Gene Research, Chief Research Scientist 2006: (財)かずさDNA研究所, ヒトゲノム研究部・ゲノム解析技術研究室, 主任研究員 2005: Kazusa DNA Research Institute, Department of Human Gene Research, Chief Research Scientist, ヒト遺伝子研究部, 主任研究員 2004: 財団法人かずさディー・エヌ・エー研究所, ヒト遺伝子研究部, 主任研究員 Less
Review Section/Research Field	Principal Investigator Applied genomics / Laboratory animal science / Genome biology / Genome biology / Basic Section 43050:Genome biology-related Except Principal Investigator Hematology / Basic Section 43010:Molecular biology-related
Keywords	Principal Investigator 遺伝子 / ゲノム / 動物 / 発生・分化 / バイオテクノロジー / 機能ゲノム / 病態モデル動物 / 部位特異的組み換え / KIAA / 脳・神経 … More / 巨大蛋白質 / comprehensive analysis / functional genomics / large protein / KO mice / human genome project / early development / ゲノムエンジニアリング / アポトーシス / 有用遺伝子探索 / 染色体工学 / 遺伝子改変動物 / ゲノム編集 / ゲノム操作技術 / 病態モデルマウス / 包括的機能解析 / ノックアウトマウス / ヒトゲノム / 脳特異的 / 初期発生 / brain specific expression / 蛋白質複合体 / protein complexes / ゲノム改変技術 / 部位特異的組み換え酵素 / VCre/VloxP / SCre/SloxP / エピジェネティックス / 修飾塩基 / エピジェネティクス / 発現制御 / モザイク変異 / 体細胞突然変異 / 疾患モデルマウス … More Except Principal Investigator 骨髄異形成症候群 / 急性骨髄性白血病 / 遺伝子改変マウス / 新規遺伝子変異 / DDX41 / マウスモデル / 遺伝子変異 / ヘテロクロマチン / ncRNA / メチル化 / Suv39h1 Less

体細胞モザイク変異疾患モデルマウスとLOH検出マウスの開発Principal Investigator
- Principal Investigator
  
  中山学
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Kazusa DNA Research Institute
Ectopic assembly of mammalian heterochromatin triggered by tandem repetitive DNA
- Principal Investigator
  
  Shirai Atsuko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Institute of Physical and Chemical Research
Biological characterization of DDX41 germline and somatic mutations in myeloid neoplasms
- Principal Investigator
  
  Kon Ayana
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
Development of a method to directly introduce a chemically modified DNA cassette into the target region of a genomePrincipal Investigator
- Principal Investigator
  
  Nakayama Manabu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Genome biology
- Research Institution
  Kazusa DNA Research Institute
New site-specific recombination systems for genome engineering, VCre/VloxP and SCre/SloxPPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA MANABU
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Genome biology
- Research Institution
  Kazusa DNA Research Institute
Improvement of high-throughput method to generate the knock-in ESPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Manabu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied genomics
- Research Institution
  Kazusa DNA Research Institute
アポトーシス誘導活性増強システムを用いたミクログリア欠損マウスの作製と解析Principal Investigator
- Principal Investigator
  
  中山学
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Kazusa DNA Research Institute
Functional characterization of KIAA genes by gene-targeted disruption and identification of biological protein complexes containing the large proteinsPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Manabu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied genomics
- Research Institution
  Kazusa DNA Research Institute
A gene-targeting approach for functional characterization of KIAA genes encoding extremely large proteinsPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Manabu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied genomics
- Research Institution
  Kazusa DNA Research Institute

[Journal Article] H3K14 ubiquitylation promotes H3K9 methylation for heterochromatin assembly2019
- Author(s)
  Oya Eriko、Nakagawa Reiko、Yoshimura Yuriko、Tanaka Mayo、Nishibuchi Gohei、Machida Shinichi、Shirai Atsuko、Ekwall Karl、Kurumizaka Hitoshi、Tagami Hideaki、Nakayama Jun‐ichi
- Journal Title
  
  EMBO reports
  
  Volume: 20
- DOI
  10.15252/embr.201948111
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06071, KAKENHI-PLANNED-18H05532, KAKENHI-PLANNED-18H05534, KAKENHI-PROJECT-17H03713
[Journal Article] Physiological Srsf2 P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice.2018
- Author(s)
  Kon Ayana、Yamazaki Satoshi、Nannya Yasuhito、Kataoka Keisuke、Ota Yasunori、Nakagawa Masahiro Marshall、Yoshida Kenichi、Shiozawa Yusuke、Morita Maiko、Yoshizato Tetsuichi、Sanada Masashi、Nakayama Manabu、Koseki Haruhiko、Nakauchi Hiromitsu、Ogawa Seishi
- Journal Title
  
  Blood Adv
  
  Volume: 131 Pages: 621-635
- DOI
  10.1182/blood-2017-01-762393
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-17H05086, KAKENHI-PROJECT-16K19574
[Journal Article] Novel reporter and deleter mouse strains generated using VCre/VloxP and SCre/SloxP systems, and their system specificity in mice2018
- Author(s)
  Yoshimura Y, Ida-Tanaka M, Hiramaki T, Goto M, Kamisako T, Eto T, Yagoto M, Kawai K, Takahashi T, Nakayama M, Ito M.
- Journal Title
  
  Transgenic Research
  
  Volume: 27 Pages: 193-201
- DOI
  10.1007/s11248-018-0067-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07208
[Journal Article] Generating a transgenic mouse line stably expressing human MHC surface antigen from a HAC carrying multiple genomic BACs.2015
- Author(s)
  Hasegawa Y, Ishikura T, Hasegawa T, Watanabe T, Suzuki J, Nakayama M, Okamura Y, Okazaki T, Koseki H, Ohara O, Ikeno M, and Masumoto H
- Journal Title
  
  Chromosoma
  
  Volume: 124(1) Pages: 107-118
- DOI
  10.1007/s00412-014-0488-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23114008, KAKENHI-PROJECT-24310143
[Journal Article] VCre/VloxP and SCre/SloxP : new site-specific recombination systems for genome engineering.2011
- Author(s)
  Suzuki E., Nakayama M.
- Journal Title
  
  Nucleic Acids Res. Vol.39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310123
[Journal Article] Recombinase-mediated cassette exchange (RMCE) and BAC engineering via VCre/VloxP and SCre/SloxP systems.2011
- Author(s)
  Minorikawa S., Nakayama M.
- Journal Title
  
  BioTechniques Vol.50
  
  Pages: 235-246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310123
[Journal Article] Homologous recombination in human iPS and ES cells for use in gene correction therapy.2010
- Author(s)
  Nakayama M.
- Journal Title
  
  Drug Discov.Today Vol.15
  
  Pages: 198-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310123
[Journal Article] Extracellular Calcium Controls Background Current and Neuronal Excitability via an UNC79-UNC80-NALCN Cation Channel Complex.2010
- Author(s)
  Lu B., Zhang Q., Wang H., Wang Y., Nakayama M., Ren D.
- Journal Title
  
  Neuron Vol.68
  
  Pages: 488-499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310123
[Journal Article] Homologous recombination in human iPS and ES cells for use in gene correction therapy2010
- Author(s)
  Nakayama M.
- Journal Title
  
  Drug Discov.Today 15
  
  Pages: 198-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310123
[Journal Article] Defining the immunological phenotype of Fc receptor-like B (FcRLB) deficient mice : confounding role of the inhibitory Fc γ RIIb.2010
- Author(s)
  Masuda K., Mori H., Ohara O., Nakayama M., Wang J., Burrows P.
- Journal Title
  
  Cellular Immunology Vol.266
  
  Pages: 24-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310123
[Journal Article] Eliminating target cells by inducing apoptosis-related factors using hTERT promoter.2010
- Author(s)
  Takashina T., Nakayama M.
- Journal Title
  
  Open Biotechnol J Vol.4
  
  Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310123
[Journal Article] Cell therapy using induced pluripotent stem (iPS) cells meets next-next generation DNA sequencing technology.2009
- Author(s)
  Nakayama M.
- Journal Title
  
  Curr.Genomics Vol.10
  
  Pages: 303-305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310123
[Journal Article] Requirement of MARCH-I-mediated MHC II ubiquitination for the maintenance of conventional dendritic cells.2009
- Author(s)
  Ohmura-Hoshino M, Matsuki Y, Mito-Yoshida M, Goto E, Aoki-Kawasumi M, Nakayama M, Ohara O, Ishido S
- Journal Title
  
  J Immunol. Vol.11
  
  Pages: 6893-6897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310123
[Journal Article] Engineered FADD induces apoptosis via an artificial death-inducing signaling complex (DISC).2009
- Author(s)
  Suzuki E, Takashina T., Nakayama M.
- Journal Title
  
  Int J Biomed Sci. Vol.5
  
  Pages: 237-245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310123
[Journal Article] Cell therapy using induced pluripotent stem(iPS)cells meets next-next generation DNA sequencing technology2009
- Author(s)
  Nakayama M.
- Journal Title
  
  Current Genomics 10
  
  Pages: 303-305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310123
[Journal Article] The zinc transporter SLC39A13/ZIP13 is required for connective tissue development ; its involvement in BMP/TGF-beta signaling pathways.2008
- Author(s)
  Fukada T, Civic N, Furuichi T, Shimoda S, Mishima K, Higashiyama H, Idaira Y, Asada Y, Kitamura H, Yamasaki S, Hojyo S, Nakayama M, Ohara O, Koseki H, Dos Santos HG, Bonafe L, Ha-Vinh R, Zankl A, Unger S, Kraenzlin ME, Beckmann JS, Saito I, Rivolta C, Ikegawa S, Superti-Furga A, Hirano T
- Journal Title
  
  PLoS ONE. Vol.3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310123
[Journal Article] Rapid single-tube method for small-scale affinity purification of polyclonal antibodies using Halo Tagtrade mark Technology2007
- Author(s)
  Hata T, Nakayama M.
- Journal Title
  
  J Biochem Biophys Methods 70
  
  Pages: 679-682
- Data Source
  KAKENHI-PROJECT-18310137
[Journal Article] MEGF10 is a mammalian ortholog of CED-1 that interacts with clathrin assembly protein complex 2 medium chain and induces large vacuole formation.2007
- Author(s)
  Suzuki E., Nakayama M
- Journal Title
  
  Exp. Cell Res. 313
  
  Pages: 3729-3742
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18310137
[Journal Article] The mammalian Ced-1 ortholog MEGF10/KIAA1780 displays a novel adhesion pattern2007
- Author(s)
  Suzuki E, Nakayama M.
- Journal Title
  
  EXP.Cell Res. in press
- Data Source
  KAKENHI-PROJECT-18310137
[Journal Article] Targeted disruption of the murine large nuclear KIAA1440/Ints1 protein causes growth arrest in early blastocyst stage embryos and eventual apoptotic cell death2007
- Author(s)
  Hata T, Nakayama M
- Journal Title
  
  Biochimica et Biophysica Acta(BBA)-Molecular Cell Research in press
- Data Source
  KAKENHI-PROJECT-18310137
[Journal Article] The mammalian Ced-1 ortholog MEGF10/KIAA1780 displays a novel adhesion pattern.2007
- Author(s)
  Suzuki E. Nakayama M
- Journal Title
  
  Exp. Cell Res.(peer-reviewed) 313
  
  Pages: 2451-2464
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18310137
[Journal Article] Targeted disruption of the murine large nuclear KLAA1440/Intsl protein causes growth arrest in early blastocyst stage embryos and eventual apoptotic cell death.2007
- Author(s)
  Hata T. Nakayama M
- Journal Title
  
  Biochimica et Biophysica Acta(BBA) Molecular Cell Research 1773
  
  Pages: 1039-1051
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18310137
[Journal Article] Rapid single-tube method for small-scale affinity purification of polyclonal antibodies using HaloTag Technology.2007
- Author(s)
  Hata T. Nakayama M
- Journal Title
  
  J Biochem Biophys Methods(peer-reviewed) 70
  
  Pages: 679-682
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18310137
[Journal Article] A gene-targeting approach for functional characterization of KIAA genes encoding extremely large proteins2006
- Author(s)
  Nakayama, M.
- Journal Title
  
  FASEB J. 20
  
  Pages: 1718-1720
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310137
[Journal Article] A gene-targeting approach for function characterization of KIAA genes encoding extremely large proteins2006
- Author(s)
  Nakayama, M. et al.
- Journal Title
  
  FASEB J 20
  
  Pages: 1718-1720
- Data Source
  KAKENHI-PROJECT-18310137
[Journal Article] A gene-targeting approach for functional characterization of KIAA genes encoding extremely large proteins2006
- Author(s)
  Nakayama, M
- Journal Title
  
  FASWB J. In press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310141
[Journal Article] Agene-targeting approach for functional characterization of KLAA genes encoding extremely large proteins.2006
- Author(s)
  Nakayama, M., Iida, M., Koseki, H., Ohara, O
- Journal Title
  
  FASEB J.(peer-reviewed) 20
  
  Pages: 1718-1920
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18310137
[Journal Article] A gene-targeting approach for functional characterization of KIAA genes encoding extremely large proteins2006
- Author(s)
  Nakayama, M.
- Journal Title
  
  FASEB J. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310141
[Journal Article] A gene-targeting approach for functional characterization of KIAA genes encoding extremely large proteins2006
- Author(s)
  Nakayama, M
- Journal Title
  
  FASEB J. (In press)
- Data Source
  KAKENHI-PROJECT-16310141
[Journal Article] Improvement of recombination efficienc by mutation of red proteins2005
- Author(s)
  Nakayama, M.
- Journal Title
  
  Biotechniques Vol38
  
  Pages: 917-924
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310141
[Journal Article] Improvement of recombination efficiency by mutation of red proteins2005
- Author(s)
  Nakayama, M.
- Journal Title
  
  Biotechniques 38
  
  Pages: 917-924
- Data Source
  KAKENHI-PROJECT-16310141
[Journal Article] Inprovement of recombination efficiency by mutation of red proteins2005
- Author(s)
  Nakayama, M.
- Journal Title
  
  Biotechniques 38
  
  Pages: 917-924
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310141
[Journal Article] Cell therapy using induced pluripotent stem (iPS) cells meets next-next generation DNA sequencing technology
- Author(s)
  M. Nakayama
- Journal Title
  
  Current Genomics (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310123
[Patent] 新規な部位特異的組換え酵素とその認識配列を用いた部位特異的組換え方法2009
- Inventor(s)
  中山学
- Industrial Property Rights Holder
  かずさDNA研究所
- Industrial Property Number
  2009-136830
- Filing Date
  2009-06-08
- Data Source
  KAKENHI-PROJECT-20310123
[Patent] 新規な部位特異的組換え酵素とその認識配列を用いた部位特異的組換え方法2009
- Inventor(s)
  中山学
- Industrial Property Rights Holder
  かずさDNA研究所
- Filing Date
  2009-10-29
- Data Source
  KAKENHI-PROJECT-20310123
[Presentation] 反復配列に引き起こされる哺乳類異所的高次クロマチン形成系の構築と解析2021
- Author(s)
  白井　温子、大関淳一郎、舛本寛、中山学、眞貝洋一
- Organizer
  第14回日本エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-18K06071
[Presentation] 反復配列に引き起こされる哺乳類異所的高次クロマチン形成系の構築と解析2021
- Author(s)
  白井　温子、大関淳一郎、舛本寛、中山学、眞貝洋一
- Organizer
  第38 回染色体ワークショップ第19 回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-18K06071
[Presentation] Ectopic assembly of mammalian heterochromatin triggered by tandem repetitive DNA2019
- Author(s)
  白井温子、大関淳一郎、舛本寛、中山学、眞貝洋一
- Organizer
  RIKEN Epigenetics in Wako
- Data Source
  KAKENHI-PROJECT-18K06071
[Presentation] 哺乳類異所的高次クロマチン形成系の構築と解析2019
- Author(s)
  白井温子、大関淳一郎、舛本寛、中山学、眞貝洋一
- Organizer
  第 36 回染色体ワークショップ
- Data Source
  KAKENHI-PROJECT-18K06071
[Presentation] Biological characterization of DDX41 germline and somatic mutations in myeloid neoplasms.2017
- Author(s)
  Ayana Kon, Keisuke Kataoka, June Takeda, Tetsuichi Yoshizato, Masahiro Nakagawa, Yasunori Kogure, Kenichi Yoshida, Manabu Nakayama, Haruhiko Koseki, Hideki Makishima, Seishi Ogawa
- Organizer
  日本癌学会総会
- Data Source
  KAKENHI-PROJECT-16K19574
[Presentation] Biological characterization of DDX41 germline and somatic mutations in myeloid neoplasms.2017
- Author(s)
  Ayana Kon, Keisuke Kataoka, Hideki Makishima, June Takeda, Tetsuichi Yoshizato, Masahiro Nakagawa, Yasunori Kogure, Kenichi Yoshida, Manabu Nakayama, Haruhiko Koseki, Seishi Ogawa
- Organizer
  日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19574
[Presentation] The biological characterization of Srsf2 P95H mutation in the pathogenesis of myelodysplasia2016
- Author(s)
  Ayana Kon, Satoshi Yamazaki, Yusuke Shiozawa, Keisuke Kataoka, Yasunori Ota, Maiko Morita, Tetsuichi Yoshizato, Masashi Sanada, Kenichi Yoshida, Hideki Makisima, Yasuhito Nanya, Shinichi Kotani, June Takeda, Yosaku Watatani, Yotaro Ochi, Manabu Nakayama, Haruhiko Koseki, Hiromitsu Nakauchi, Seishi Ogawa
- Organizer
  The 78th Annual Meeting of the Japanese Society of Hematology
- Place of Presentation
  Yokohama, Kanagawa, Japan
- Data Source
  KAKENHI-PROJECT-16K19574
[Presentation] 次世代シーケンサー(MiSeq)を用いた原発性免疫不全症の遺伝子解析2015
- Author(s)
  中山　学, 小田紘嗣, 八角高裕, 西小森隆太, 平家俊男, 小原　收
- Organizer
  第8回日本免疫不全症研究会
- Place of Presentation
  東京
- Year and Date
  2015-01-24
- Data Source
  KAKENHI-PROJECT-24310143
[Presentation] 新規部位特異的組み換えシステム（VCre/VloxP・SCre/SloxP）を用いたゲノム改変技術の開発と応用2013
- Author(s)
  御法川さち子、中山学
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートランド
- Data Source
  KAKENHI-PROJECT-24310143
[Presentation] 新しい部位特異的組み換えシステム(VCreyVloxP・SCre/SloxP)を用いたゲノム改変技術の開発2012
- Author(s)
  中山学
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-24310143
[Presentation] 新規部位特異的組み換えシステムを用いたゲノム改変技術の開発2010
- Author(s)
  中山学
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-20310123
[Presentation] ノックイン胚性幹細胞作製の迅速化と新規ゲノム改変技術の開発2009
- Author(s)
  中山学
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-20310123
[Presentation] 包括的機能研究のためのノックイン胚性幹細胞作製の迅速化と解析2008
- Author(s)
  中山学
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20310123
[Presentation] 包括的機能研究のためのノックイン胚性幹細胞作製の迅速化と解析2008
- Author(s)
  中山学
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20310123
[Presentation] Functional analysis of large nuclear KIAA1440/Ints1 protein involved in development and survival of mouse early embryo2007
- Author(s)
  Hata T. Nakayama M.
- Organizer
  Biochemistry and Molecular Biology
- Place of Presentation
  Yokahama
- Year and Date
  2007-12-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18310137

1. KOSEKI Haruhiko (40225446)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. Kon Ayana (20772403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. OGAWA Seishi (60292900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. Shirai Atsuko (60525575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. SANADA Masashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. Kataoka Keisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 岡崎孝映

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 舛本寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 中内啓光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 山崎聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 中山潤一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 胡桃坂仁志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakayama Manabu 中山 学

NAKAYAMA Manabu 中山 学

NAKAYAMA MANABU 中山 学

Research Projects

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Co-Researchers

体細胞モザイク変異疾患モデルマウスとLOH検出マウスの開発Principal Investigator

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Ectopic assembly of mammalian heterochromatin triggered by tandem repetitive DNA

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Biological characterization of DDX41 germline and somatic mutations in myeloid neoplasms

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Development of a method to directly introduce a chemically modified DNA cassette into the target region of a genomePrincipal Investigator

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New site-specific recombination systems for genome engineering, VCre/VloxP and SCre/SloxPPrincipal Investigator

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Improvement of high-throughput method to generate the knock-in ESPrincipal Investigator

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アポトーシス誘導活性増強システムを用いたミクログリア欠損マウスの作製と解析Principal Investigator

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Functional characterization of KIAA genes by gene-targeted disruption and identification of biological protein complexes containing the large proteinsPrincipal Investigator

Principal Investigator

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A gene-targeting approach for functional characterization of KIAA genes encoding extremely large proteinsPrincipal Investigator

Principal Investigator

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[Journal Article] H3K14 ubiquitylation promotes H3K9 methylation for heterochromatin assembly2019

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[Journal Article] Physiological Srsf2 P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice.2018

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[Journal Article] Novel reporter and deleter mouse strains generated using VCre/VloxP and SCre/SloxP systems, and their system specificity in mice2018

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[Journal Article] Generating a transgenic mouse line stably expressing human MHC surface antigen from a HAC carrying multiple genomic BACs.2015

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Nakayama Manabu 中山学

NAKAYAMA Manabu 中山学

NAKAYAMA MANABU 中山学