YUASA Shigeki 湯浅茂樹

Researcher Number	70127596
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2009: National Center of Neurology and Psychiatry, 神経研究所微細構造研究部, 部長 2007 – 2008: 国立精神・神経センター, 神経研究所微細構造研究部, 部長 2006 – 2008: 国立精神・神経センター, 神経研究所・微細構造研究部, 部長 2006: National Institute of Neuroscience, Department of Ultrastructural Research, Director, 神経研究所微細構造研究部, 部長 2005: 国立精神・神経センター, 微細構造研究部, 部長 … More 2002: 国立精神・神経センター, 微細構造研究部, 部長 2001: 千葉大学, 大学院・医学研究院, 教授 1996 – 2000: 千葉大学, 医学部, 教授 1994 – 1995: 岡崎国立共同研究機構, 生理学研究所, 助教授 1992 – 1993: 慶應義塾大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Pediatrics / Embryonic/Neonatal medicine / Neuroscience in general / Cerebral neurosurgery Except Principal Investigator Cerebral neurosurgery / 応用微生物学・応用生物化学 / Neurology / Biological Sciences / Neuroscience in general
Keywords	Principal Investigator 扁桃体 / アストログリア / Fynチロシンキナーゼ / NMDA受容体 / 海馬 / リーラーミュータントマウス / プルキンエ細胞 / 小脳発生 / 神経細胞移動 / Tenascin … More / 記憶の消去 / 文脈的記憶 / 恐怖条件付け / 情動記憶 / Fyn チロシンキナーゼ / 情動 / 細胞移動 / tenascin / Bergmannグリア / cDNA array / in utero electroporation / NMDA receptor / emotion / striatum / amygdala / neuronal migration / Fyn tyrosine kinase / エレクトロポレーション / マイクロダイセクション / 神経新生 / cDNAマイクロアレイ / 子宮内エレクトロポレーション / 線条体 / Bergmann glia / Cell adhesion molecule / Neuronal migration / Contact guidance / Reeler / Radial glia / In situ hybridization / in situ hybridization / 細胞接着因子 / bromodeoxyuridine / GFAP / 放射状グリア / リーラーマウス / 細胞内情報伝達 / 脱リン酸化酵素 / 消去 / ドーパミン神経伝達 / 細胞内シグナル伝達 / プロテオミクス / PTSD / huntingtin / アミノ酸配列 / 微小管 / ノックアウトマウス / 抗体 / cDNA / データベース / 遺伝子発現 / プロモーター / 神経移植 / 神経損傷 / ヘルペスチミジンキナーゼ / 転写調節 / 遺伝子導入 / 移植 / 神経再生 / テネイシン / DiI / 顆粒細胞 / 蝸牛神経背側核 / rhombotin / 帯状構造 … More Except Principal Investigator PSA-NCAM / Bromodeoxyuridine / Neurogenesis / Kindling / c-fos / 海馬 / Vestibular stimulation / Tyrosine hydroxylase / Immediate early genes / Neurotoxin / Quinolonic acid / E1 mice / Epilepsy / 前庭刺激 / チロシンヒドロキシラーゼ / 初期遺伝子 / ELマウス / 神経毒 / キノリン酸 / てんかん / Mouse / Granule cell / Hippocampus / Purkinje cells / Cerebellum / Oncogene / Immortalized cell / Neural transplantation / 神経栄養因子 / 温度感受性発癌遺伝子 / 神経成長栄養因子 / 細胞移動 / 遺伝子導入 / 神経分化 / 可塑性 / 神経修復 / マウス / 顆粒細胞 / プルキンエ細胞 / 小脳 / 発癌遺伝子 / 不死化細胞株 / 神経移植 / プロテアーぜ / アミロイド / プロテアーゼ / 認知症 / アルツハイマー病 / 細胞死 / ホメオボックス / bmi-1 / mel-18 / 哺乳類 / MPH2 / Bmi1 / Mel18 / Hox / スプライセオソーム / クロマチン / ポリコーム群 / 躁うつ病 / 精神分裂病 / 扁桃体 / 意欲 / 情動 Less

遺伝子改変動物を用いた恐怖情動記憶消去の分子神経機構の解明Principal Investigator
- Principal Investigator
  
  湯浅茂樹
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Center of Neurology and Psychiatry
Elucidation of the regulation mechanisms of activity, expression and cellular localization of β-secretase in neuronal cells
- Principal Investigator
  
  ARAKI Wataru
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  National Center of Neurology and Psychiatry
遺伝子改変マウスを用いた情動記憶消去の分子神経機構の解明Principal Investigator
- Principal Investigator
  
  湯浅茂樹
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Center of Neurology and Psychiatry
Analysis of the molecular bases on the stress sensitivity and abnormal emotional function in the developmental process of Fyn-deficient mice.Principal Investigator
- Principal Investigator
  
  YUASA Shigeki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  National Center of Neurology and Psychiatry
ヒト脳内長鎖cDNA解析データベースを基盤としたマウス扁桃体の情動神経機構の解明Principal Investigator
- Principal Investigator
  
  湯浅茂樹
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neuroscience in general
- Research Institution
  National Center of Neurology and Psychiatry
  Chiba University
脳のパターン形成と細胞死抑制の課程における哺乳類ポリコーム群の機能発現機序
- Principal Investigator
  
  古関明彦
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
The expression of apoptosis neurogenesis and axonal sprouting in epileptitogenic focus
- Principal Investigator
  
  MINE Seiichiro
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Chiba University
情動・意欲の神経機構と病態のメカニズム
- Principal Investigator
  
  KAWAMURA Koki
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  Keio University
アストログリア-サブセットの分子細胞工学的選別と移植による損傷中枢神経の再生促進Principal Investigator
- Principal Investigator
  
  湯浅茂樹
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Chiba University
Hyper Sensitivity of the Brain of Epileptogenic E1 Mice to Vestibular Neuronal Stimulation
- Principal Investigator
  
  NAKANO Kiwao
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Nagoya University
小脳神経回路形成における標的認識の分子機構Principal Investigator
- Principal Investigator
  
  湯浅茂樹
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Chiba University
小脳求心性投射の形成と安定化の分子機構Principal Investigator
- Principal Investigator
  
  湯浅茂樹
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okazaki National Research Institutes
Molecular mechanisms of defective cortical histogenesis in the cerebellar development.Principal Investigator
- Principal Investigator
  
  YUASA Shigeki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Okazaki National Research Institutes
Reconstruction of neural tissue by means of transplantation of immortalized cell line generated by transfer of oncogene (tsA58)
- Principal Investigator
  
  KAWAMURA Koki
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Keio University, School of Medicine

All 2010 2009 2007 2006

All Journal Article Book

[Book] 先進脳・神経科学(高坂新一監修,中村俊編著) Part1.4 細胞内シグナル伝達系-高次脳機能の制御2006
- Author(s)
  湯浅茂樹, 服部功太郎その他
- Total Pages
  193
- Publisher
  培風館
- Data Source
  KAKENHI-PROJECT-17591130
[Book] 先進脳・神経科学(Part 1. 4細胞内シグナル伝達系-高次脳機能の制御)(高坂新一監修,中村俊編著)2006
- Author(s)
  湯浅茂樹, 服部功太郎その他
- Total Pages
  193
- Publisher
  培風館
- Data Source
  KAKENHI-PROJECT-18019044
[Book] 脳神経外科学体系第1巻神経科学中枢神経発生分化のメカニズム2006
- Author(s)
  湯浅茂樹, 中平英子(分担執筆)
- Total Pages
  386
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-17591130
[Book] 先進脳・神経科学細胞内シグナル伝達系-高次脳機能の制御.(pp.53-72)(高坂新- 監修,中村俊編著)2006
- Author(s)
  湯浅茂樹, 服部功太郎, 甲斐信行, 中平英子, 伊早坂智子, 八木健
- Total Pages
  193
- Publisher
  培風館
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591130
[Journal Article] Hippocampal SH2-containing protein-tyrosine phosphatases are involved in extinction of contextual fear.2010
- Author(s)
  Isosaka T, Yuasa S
- Journal Title
  
  Neuroreport 21
  
  Pages: 554-558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20019040
[Journal Article] 扁桃体機能におけるsomatotopy-情動発現の機構から2009
- Author(s)
  湯浅茂樹
- Journal Title
  
  Brain and Nerve 61
  
  Pages: 1395-1404
- Data Source
  KAKENHI-PROJECT-20019040
[Journal Article] Hippocampal Fyn activity regulates extinction of contextual fear.2009
- Author(s)
  Isosaka T, Kida S, Kohno T, Hattori K, Yuasa S
- Journal Title
  
  Neuroreport 20
  
  Pages: 1461-1465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20019040
[Journal Article] Mice lacking α1, 3-fucosyltransferase IX demonstrate disappearance of Lewis x structure in brain and increased anxiety-like behaviors.2007
- Author(s)
  Kudo T., Yuasa S., Narimatsu H.et al.
- Journal Title
  
  Glycobiology 17
  
  Pages: 1-9
- Data Source
  KAKENHI-PROJECT-17591130
[Journal Article] Loss of alpha-tubulin polyglutamy lation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulate synaptic function.2007
- Author(s)
  Ikegami K., Yuasa S., Setou M.et al.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA. 104
  
  Pages: 3213-3218
- Data Source
  KAKENHI-PROJECT-18019044
[Journal Article] Constitutive activation of neuronal Src causes aberrant dendritic morphogenesis in mouse cerebellar Purkinje cells.2007
- Author(s)
  Kotani T., Yuasa S., Okada M.et al.
- Journal Title
  
  Neuroscience Research 57
  
  Pages: 210-219
- NAID
  10021188766
- Data Source
  KAKENHI-PROJECT-18019044
[Journal Article] Constitutive activation of neuronal Src causes aberrant dendritic morphogenesis in mouse cerebellar Purkinje cells.2007
- Author(s)
  Kotani T., Yuasa S., Okada M.et al.
- Journal Title
  
  Neuroscience Research 57
  
  Pages: 210-219
- NAID
  10021188766
- Data Source
  KAKENHI-PROJECT-17591130
[Journal Article] Loss of alpha-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulate synaptic function.2007
- Author(s)
  Ikegami K., Yuasa S., Setou M.et al.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA. 104
  
  Pages: 3213-3218
- Data Source
  KAKENHI-PROJECT-17591130
[Journal Article] Mice lacking α1, 3-fucosyltransferase IX demonstrate disappearance of Lewis x structure in brain and increased anxiety-like behaviors.2007
- Author(s)
  Kudo T., Yuasa S., Narimatsu H.et al.
- Journal Title
  
  Glycobiology 17
  
  Pages: 1-9
- Data Source
  KAKENHI-PROJECT-18019044
[Journal Article] 情動・記憶の分子基盤2006
- Author(s)
  湯浅茂樹, 甲斐信行, 相馬美歩
- Journal Title
  
  神経研究の進歩 50・1
  
  Pages: 25-37
- Data Source
  KAKENHI-PROJECT-17591130
[Journal Article] Fyn activation is required for haloperidol-induced catalepsy in mice.2006
- Author(s)
  Hattori K, Uchino S, Isosaka T, Maekawa M, Iyo M, Sato T, Kohsaka S, Yagi T, Yuasa S.
- Journal Title
  
  Journal of Biological Chemistry 281(11)
  
  Pages: 7129-7135
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591130
[Journal Article] Fyn activation is required for haloperidol-induced catalepsy in mice.2006
- Author(s)
  Hattori K, Uchino S, Isosaka T, Maekawa M, Iyo M, Sato T, Kohsaka S, Yagi T, Yuasa S
- Journal Title
  
  Journal of Biological Chemistry 281(11)
  
  Pages: 7129-7135
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591130
[Journal Article] 発達障害仮説における大脳皮質形成関連遺伝子の意義2006
- Author(s)
  服部功太郎, 伊早坂智子, 湯浅茂樹, 八木健
- Journal Title
  
  脳と精神の医学 17(1)
  
  Pages: 65-72
- NAID
  10029852944
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591130
[Journal Article] 情動・記憶の分子基盤2006
- Author(s)
  湯浅茂樹, 甲斐信行, 相馬美歩
- Journal Title
  
  神経研究の進歩 50(1)
  
  Pages: 25-37
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591130
[Journal Article] Altered gene expression in the subdivisions of the amygdala of Fyn-deficient mice as revealed by laser capture microdissection and mKIAA cDNA array analysis.2006
- Author(s)
  Kai N, Iwase K, Imai K, Nakahira E, Soma M, Ohtsuka S, Yagi T, Kobayashi K, Koga H, Takiguchi M, Yuasa S.
- Journal Title
  
  Brain Research 1073-1074
  
  Pages: 60-70
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591130
[Journal Article] Three-dimensional reconstruction of the membrane skeleton at the plasma membrane interface by electron tomnpraghy.2006
- Author(s)
  Morone N., Yuasa S., Kusumi A.et al.
- Journal Title
  
  Journal of Cell Biology 174
  
  Pages: 851-862
- Data Source
  KAKENHI-PROJECT-18019044
[Journal Article] Altered gene expression in the subdivisions of the amygdala of Fyn-deficient mice as revealed by laser capture microdissection and mKIAA cDNA array analysis.2006
- Author(s)
  Kai N, Iwase K, Imai K, Nakahira E, Soma M, Ohtsuka S, Yagi T, Kobayashi K, Koga H, Takiguchi M, Yuasa S
- Journal Title
  
  Brain Research 1073-1074
  
  Pages: 60-70
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591130
[Journal Article] Altered gene expression in the subdivision of the amygdala of Fyn-deficient mice as revealed by laser capture microdissection and mKIAA cDNA array analysis.2006
- Author(s)
  Kai, N., Iwase, K., Imai, K., Nakahira, E., Soma, M., 他5名, Yuasa, S.
- Journal Title
  
  Brain Research 1073-1074
  
  Pages: 60-70
- Data Source
  KAKENHI-PROJECT-17591130
[Journal Article] Three-dimensional reconstruction of the membrane skeleton at the plasma membrane interface by electron tomography.2006
- Author(s)
  Morone N., Yuasa S., Kusumi A.et al.
- Journal Title
  
  Journal of Cell Biology 174
  
  Pages: 851-862
- Data Source
  KAKENHI-PROJECT-17591130
[Journal Article] Fyn is required for haloperidol-induced catalepsy in mice.2006
- Author(s)
  Hattori, K., Uchino, S., Isosaka, T, 他3名, Kohsaka, S., Yagi, T., Yuasa, S.
- Journal Title
  
  Journal of Biological Chemistry 281・11
  
  Pages: 7129-7135
- Data Source
  KAKENHI-PROJECT-17591130

1. KAWAMURA Koki (40048286)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. HATTORI Kotaro (50415569)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. SOMA Miho (70328756)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. KAMETANI Fuyuki (70186013)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KONISHI Yoshihiro (90170290)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. ITOH Masayuki (50243407)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 古関明彦 (40225446)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. ARAKI Wataru (60311429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NAKANO Kiwao (10023433)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KITOH Junzoh (60022802)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MINE Seiichiro (70190709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MURAI Hisayuki (80241967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YAMAURA Akira (40009717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NAKAHIRA Eiko (10392432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
15. 西川徹 (00198441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 神庭重信 (50195187)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 小幡邦彦 (60013976)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 岡戸信男 (50060140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 加藤怜子 (00392431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 前川素子 (50435731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 岩佐博人 (60203361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KUME Hideaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. TAMAOKA Akira

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. ODA Akiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. OGINO Koichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 小原收

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 小原収

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YUASA Shigeki 湯浅 茂樹

Research Projects

Research Products

Co-Researchers

遺伝子改変動物を用いた恐怖情動記憶消去の分子神経機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the regulation mechanisms of activity, expression and cellular localization of β-secretase in neuronal cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

遺伝子改変マウスを用いた情動記憶消去の分子神経機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the molecular bases on the stress sensitivity and abnormal emotional function in the developmental process of Fyn-deficient mice.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト脳内長鎖cDNA解析データベースを基盤としたマウス扁桃体の情動神経機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脳のパターン形成と細胞死抑制の課程における哺乳類ポリコーム群の機能発現機序

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The expression of apoptosis neurogenesis and axonal sprouting in epileptitogenic focus

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

情動・意欲の神経機構と病態のメカニズム

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アストログリア-サブセットの分子細胞工学的選別と移植による損傷中枢神経の再生促進Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Hyper Sensitivity of the Brain of Epileptogenic E1 Mice to Vestibular Neuronal Stimulation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

小脳神経回路形成における標的認識の分子機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

小脳求心性投射の形成と安定化の分子機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Molecular mechanisms of defective cortical histogenesis in the cerebellar development.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

YUASA Shigeki 湯浅茂樹

[Book] 先進脳・神経科学(高坂新一監修,中村俊編著) Part1.4 細胞内シグナル伝達系-高次脳機能の制御2006

[Book] 先進脳・神経科学(Part 1. 4細胞内シグナル伝達系-高次脳機能の制御)(高坂新一監修,中村俊編著)2006

[Book] 脳神経外科学体系第1巻神経科学中枢神経発生分化のメカニズム2006

[Book] 先進脳・神経科学細胞内シグナル伝達系-高次脳機能の制御.(pp.53-72)(高坂新- 監修,中村俊編著)2006