KAWAICHI Masashi 川市正史

… Alternative Names

川市正史カワイチマサシ

Less

Researcher Number	00195041
Affiliation (based on the past Project Information) *help	2004 – 2007: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 教授 2000 – 2001: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 教授 1996: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 教授 1993 – 1994: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 教授 1993: 奈良先端科学技術大学院大学, 教授 … More 1988 – 1992: 京都大学, 医学部, 助教授 1988: 京都大学, 医学部医化学第1講座, 助教授 1987: 京都大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator General medical chemistry / General medical chemistry / Pathological medical chemistry Except Principal Investigator Pathological medical chemistry
Keywords	Principal Investigator HtrA1 / 遺伝子破壊マウス / コラーゲン / 認識DNA配列 / Suppressor of Hairless / 末梢神経系発生 / ショウジョウバエ / Hypertrophic chondrocvte / Calcification / Osteocalcine … More / Bone density / C-pronentide / Collagens / Osteoarthritis / 骨芽細胞 / 肥大軟骨 / TGF-β / プロテオグリカン / 細胞外基質 / 骨芽細胞分化 / 軟骨分化 / bFGF / 加齢黄斑変性症 / 関節炎 / HtrAセリンプロテアーゼ / 肥大軟骨細胞 / 石灰化 / オステオカルシン / 骨密度 / C-プロペプチド / コラーゲン分泌 / 変形性関節炎 / HtrAl / リンパ球分化 / T細胞抗原受容体遺伝子 / 免疫グロブリン遺伝子 / DNAメチル化 / プロT細胞 / プロB細胞 / アミロイドβ / NPXYモチーフ / PICK1 / JNKスカフォールド / LRP1B / MAPキナーゼカスケード / グルタミン酸受容体 / 細胞内取り込み / 晩発性アルツハイマー病 / JNK / JIP-1 / PICK-1 / LDL受容体ファミリー / 蛋白質分解酵素阻害剤 / セリン蛋白質分解酵素 / フォリスタチン様ドメイン / 軟骨細胞 / 関節炎モデル動物 / フォリスタチン様蛋白質 / 細胞外期質 / 変形性骨関節炎 / TGF-βファミリー / セリンプロテアーゼ / シャトルベクター / 酵母内反応 / 2重鎖DNA切断反応 / V(D)J組換え / RAG-2 / RAG-1 / transcriputional regulation / Su(H)recognition motif / promotor / Lateral inhibition / Drosophila / Hairless gene / DNA結合ドメイン / 転写調節 / Neurogenic Genes / Enhancer of Split / RBP-J_K遺伝子 / ランダムオリゴマー / コア認識配列 / ゲルシフトアッセイ / 転写因子 / E(spl)遺伝子 / NF-kB認識配列 / VDJ-組換えシグナル / RBP-Jk蛋白質 / DNA結合蛋白質 / RBP-Jκ遺伝子 / VDJ-組換え … More Except Principal Investigator TGF-β / ショウジョウバエ / 免疫グロブリン遺伝子 / 部位特異的組換え / knockout mouse / hypertrophic chondrocyte / serine protease / HtrA1 / arthritis / 骨分化 / collagen / GFG / コラーゲン / HtrA1セリンプロテアーゼ / ノックアウトマウス / 肥大化軟骨 / セリンプロテアーゼ / HtrAl / 関節炎 / Transcriptional regulator / Development / Embryonic lethal / Homologous recombination / Gene targeting / 遺伝子組換え / 末梢神経 / 胚性幹細胞 / 転写制御因子 / 胎生期致死 / 発生 / 相同遺伝子組替え / 遺伝子破壊 / 髄膜腫 / 胃癌 / loss of beterozygosity / RFLPs / 連鎖分析 / 多内分泌腫瘍症2A型(MEN2A) / エンハンサー / インターロイキン5 / インターロイキン2の受容体 / 人工突然変異 / リンフォカイン遺伝子 / IL-5遺伝子 / IL-4遺伝子 / 染色体マップ / トランスジェーニックマウス / IL-2リセプター / IL-4 / Bリンパ球の分化 / 抗体遺伝子D断片 / NK細胞 / トランスジュニックマウス / IL-2R / IL-2 / IgM^+IgG^+B細胞 / クラススイッチ / 骨髄細胞からのリンパ球への分化 / ヒト抗体V_H鎖遺伝子 / trans splicing / double isotype expression / transgenic mouse / integrase family / cDNAクローニング / DNA結合タンパク質 / 抗体遺伝子再構成 / 環状DNA / SーS組換え / リコンビナ-ゼ / ストロ-マ細胞 / 骨髄多分化能細胞 / VDJ組換 / Bリンパ球 / 遺伝子脆弱部位 / T-DNA / トランスポゾン / 標的遺伝子組換え / 非相同組換え / T細胞抗原レセプター遺伝子 / TーDNA組込み / 家族性アミロイド-シス / 遺伝子の標的組込み / DNAトポイソメラ-ゼ / DNA逆位 / クラススイッチ組換え / 抗原受容体遺伝子 / rasオンコジン / Loss of heterozygosity / 副腎褐色細胞腫 / 甲状腺髄様癌 / MEN2A / 遺伝性腫瘍 Less

Study on HtrA Serine Protea we Family Proteins Which Inhibit Signaling of TGF-βsPrincipal Investigator
- Principal Investigator
  
  KAWAICHI Masashi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nara Institute of Science and Technology
How HtrA1 serine protease inhibit TGF-β signal and is involved in arthritis ?
- Principal Investigator
  
  OKA Chio
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nara Institute of Science and Technology (NAIST)
新しいアルツハイマー病関連遺伝子LRP1Bの研究Principal Investigator
- Principal Investigator
  
  川市正史
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nara Institute of Science and Technology
セリンプロテアーゼ、S8の阻害による関節炎発症抑制の検討Principal Investigator
- Principal Investigator
  
  川市正史
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Nara Institute of Science and Technology
酵母を利用したV(D)J組換え機構の解析Principal Investigator
- Principal Investigator
  
  川市正史
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Nara Institute of Science and Technology
Hairless遺伝子の解析Principal Investigator
- Principal Investigator
  
  川市正史
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nara Institute of Science and Technology
生理機能の発現と組換え機構
- Principal Investigator
  
  池田日出男
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ショウジョウバエにおけるRBP-Jk遺伝子の機能の解析Principal Investigator
- Principal Investigator
  
  川市正史
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nara Institute of Science and Technology
ショウジョウバエにおけるRBP-JK遺伝子の機能の解析Principal Investigator
- Principal Investigator
  
  川市正史
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
抗原受容体遺伝子の組換え認識配列に結合するRBP-Jk蛋白質の特異性の研究Principal Investigator
- Principal Investigator
  
  川市正史
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Nara Institute of Science and Technology
  Kyoto University
Study on recombination signal binding protein ; RBP-Jkappa
- Principal Investigator
  
  NAKANO Toru
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kyoto University, Faculty of Medicine
生理機能の発現と組換え機構
- Principal Investigator
  
  池田日出男
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
リンパ球細胞のTーおよびBー細胞への分化決定機構の解明Principal Investigator
- Principal Investigator
  
  川市正史
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
DNA塩基配列の多型性を利用した遺伝子腫瘍の研究
- Principal Investigator
  
  高井新一郎
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
DNA塩基配列の多型性を利用した遺伝性腫瘍の研究
- Principal Investigator
  
  高井新一郎
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
免疫系における多様性発現機構の分子遺伝学的研究
- Principal Investigator
  
  本庶佑
- Project Period (FY)
  1986 – 1990
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Research Institution
  Kyoto University

All 2006 2005

All Journal Article Presentation

[Journal Article] Expression of mouse HtrA1 serine protease in normal bone and cartilage and its upregulation in joint cartilage damaged by experimental arthritis2005
- Author(s)
  Tsuchiya, A., Yano, M., Tocharus, J., Kojima, H., Fukumoto, M., Kawaichi, M., Oka, C
- Journal Title
  
  Bone 37
  
  Pages: 323-336
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390079
[Journal Article] Expression of mouse HtrA1 serine protease in normal bone and cartilage and its upregulation in joint cartilage damaged by experimental arthritis.2005
- Author(s)
  Tsuchiya, A., Yano, M., Tocharus, J., Kojima, H., Fukumoto, M., Kawaichi, M., Oka, C.
- Journal Title
  
  Bone 37
  
  Pages: 323-336
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590268
[Journal Article] Expression of mouse HtrA1 serine protease in normal bone and cartilage and its upregulation in joint cartilage damaged by experimental arthritis.2005
- Author(s)
  Tsuchiya, A., Yano, M., Tocharus, J., Kojima, H., Fukumoto, M., Kawaichi, M., Oka, C
- Journal Title
  
  Bone 37
  
  Pages: 323-336
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590268
[Journal Article] Expression of mouse HtrAl serine protease in normal bone and cartilage and its upregulation in joint cartilage damaged by experimental arthritis2005
- Author(s)
  Tsuchiya, A., Yano, M., Tocharus, J., Kojima, H., Fukumoto, M., Kawaichi, M. and Oka, C.
- Journal Title
  
  Bone 37
  
  Pages: 323-336
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390079
[Presentation] Roles of mouse HtrA1 serine protease in bone development and pathogenesis of osteoarthritis2006
- Author(s)
  Hisae, Kojima, Akiho, Tsuchiya, Masashi, Kawaichi, Chio, Oka
- Organizer
  20th IUBMB International Congress
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390079
[Presentation] Mammalian HtrAl is a highly regulated serine protease2006
- Author(s)
  Chio Oka, Murwantoko, Masato Yano, Yoshifumi Ueta, Hisae Kojima, Akiho Tsuchiya, Masashi Kawaichi
- Organizer
  20th IUBMB International Congress.
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390079
[Presentation] Roles of mouse HtrAl serine protease in bone development and pathogenesis of osteoarthritis2006
- Author(s)
  Hisae Kojima, Akiho Tsuchiya, Masashi Kawaichi, Chio Oka
- Organizer
  20th IUBMB International Congress.
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390079
[Presentation] Mammalian HtrA1 is a highly regulated serine protease2006
- Author(s)
  Chio, Oka, Murwantoko, Masato, Yano, Yoshifumi, Ueta, Hisae, Kojima, Akiho, Tsuchiya, Masashi, Kawaichi
- Organizer
  20th IUBMB International Congress
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390079

1. OKA Chio (30263445)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
2. TSUBATA Takeshi (80197756)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 高井新一郎 (80028513)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 三木哲郎 (00174003)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 池田日出男 (10012775)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 島田和典 (40037354)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 駒野照弥 (00087131)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 大石道夫 (00126004)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 本庶佑 (80090504)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 清水章 (00162694)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. NAKANO Toru (00172370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 小林哲郎 (40162002)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 山岸秀夫 (90025429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 小林泰夫 (10013319)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 佐辺寿孝 (40187282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 松浪伯禎 (40192752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 木梨達雄 (30202039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 川上敏明 (60143418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 野間隆文 (40189428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 武田俊一 (60188191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 元村和由

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. ASHBURNER Michael

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. MAK Tak W.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KAWAICHI Masashi 川市 正史

川市 正史 カワイチ マサシ

Research Projects

Research Products

Co-Researchers

Study on HtrA Serine Protea we Family Proteins Which Inhibit Signaling of TGF-βsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

How HtrA1 serine protease inhibit TGF-β signal and is involved in arthritis ?

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新しいアルツハイマー病関連遺伝子LRP1Bの研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

セリンプロテアーゼ、S8の阻害による関節炎発症抑制の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

酵母を利用したV(D)J組換え機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Hairless遺伝子の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

生理機能の発現と組換え機構

Principal Investigator

Project Period (FY)

Research Category

Research Institution

ショウジョウバエにおけるRBP-Jk遺伝子の機能の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

ショウジョウバエにおけるRBP-JK遺伝子の機能の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

抗原受容体遺伝子の組換え認識配列に結合するRBP-Jk蛋白質の特異性の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on recombination signal binding protein ; RBP-Jkappa

Principal Investigator

Project Period (FY)

Research Category

Research Institution

生理機能の発現と組換え機構

Principal Investigator

Project Period (FY)

Research Category

Research Institution

リンパ球細胞のTーおよびBー細胞への分化決定機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DNA塩基配列の多型性を利用した遺伝子腫瘍の研究

Principal Investigator

Project Period (FY)

KAWAICHI Masashi 川市正史

川市正史カワイチマサシ