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SHINADA Kazunori
島田 和典
Connect your ORCID iD
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Researcher Number
40037354
External Links
Affiliation (based on the past Project Information)
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1990 – 1999: 大阪大学, 微生物病研究所, 教授
1986 – 1989: 熊本大学, 医学部, 教授
Review Section/Research Field
Principal Investigator
Pathological medical chemistry
/
General medical chemistry
Except Principal Investigator
Human genetics
/
Biological Sciences
/
分子遺伝学・分子生理学
/
Laboratory animal science
Keywords
Principal Investigator
遺伝子標的組み込み / rae28遺伝子 / トランスサイレチン / ポリホメオティック遺伝子 / CATCH22症候群 / bmil / rae28 / neural crest / ノックアウトマウス / LD78
…
More
/ サイトカイン / 胚性幹細胞 / Gene targeting / Homologous recombination / ES細胞 / ジーンターゲティング / 神経堤細胞 / protein interactions / Polycomb group / Hox / segment specification / polyhomeotic / 疾患モデル / Hox遺伝子 / Nkx2.5 / Hand1 / ANF / rae28 gene / 発現調節 / Jurkat / K562 / プロモ-タ- / 偽遺伝子 / Actー2 / AT744 / 細胞増殖 / 炎症 / 走化性 / 発現誘導 / 相同DNA間組換え / 疾患モデルマウス / キメラマウス / プレアルブミン / アミロイド-シス / 遺伝性疾患 / Embryonic stem cell / Mouse model for human diseases / Chimeric mouse / Prealbumin / Amyloidosis / Hereditary diseases / アスパラギン酸ーリンゴ酸シャトル / アイソザイム / 細胞質型AspAT遺伝子 / ミトコンドリア型AspAT遺伝子 / 細胞質型MDH遺伝子 / ミトコンドリア型MDH遺伝子 / 遺伝子発現 / アスバラギン酸ーーリンゴ酸シャトル / GRE配列 / ミトコンドリア / マウス / 細胞質 / アスパラギン酸・リンゴ酸シャトル / トランスアミナ-ゼ / リンゴ酸脱水素酵素 / Malate-aspartate Shuttle / Isoenzyme / cAspAT / mAspAT / cMDH / mMDH / Gene Expression / 置換ベクター / ビタミンA / レチノール / レチノール結合タンパク質 / 甲状腺ホルモン / アミロイド / 血清アミロイドP成分 / ES / FAP / Transthyretin / TTR-deficient mouse / Retinol / RBP / Thyroid hormone / Replacement type vector / 相同組換え / F9細胞 / メチル化 / 遺伝病 / モデルマウス / 選択マーカー / 遺伝子標的組込み / Targeted integration / ES cell / F9 cell / Transthyretin. / Methylation / Inherited disease / 胚性腫瘍細胞 / 微小変異 / ral28遺伝子 / 臓器形成制御 / ショウジョウバエ / 臓器形成不全 / ファロ-の四徴 / polyomeotic / Pc-G遺伝子 / M33 / bmi1 / Polycomb / Pc-G遺伝子群 / polyhomeotic遺伝子 / Polycomb遺伝子 / M33遺伝子 / bmi-1遺伝子 / ポリコーム遺伝子群 / Scmh1遺伝子 / 造血幹細胞 / Hoxb3遺伝子 / 遺伝子発現維持 / レトロウイルス / Scmhl遺伝子 / Polycomb group of genes / Scmhl gene / hematopoietic stem cell / Hoxb3 gene / gene expression pattern / maintenance / retrovirus / 神経堤 / 先天性心疾患 / disease model mice / knockout mouse / Hox gene / Nkx2.5 gene / CATCH22 syndorme / congenital heart disease
…
More
Except Principal Investigator
トランスジェニックマウス / 部位特異的組換え / トランスポゾン / 血清アミロイドP成分 / 疾患モデルマウス / アミロイドーシス / 家族性アミロイドポリニューロパチー / RecA / ゲノム / 人工染色体 / 染色体地図 / ハンチントン舞踏病 / インタ-ロイキン / ミニサテライト / 動原体 / 抗原受容体遺伝子 / クラススイッチ組換え / DNA逆位 / DNAトポイソメラ-ゼ / 遺伝子の標的組込み / 家族性アミロイド-シス / TーDNA組込み / 免疫グロブリン遺伝子 / T細胞抗原レセプター遺伝子 / 非相同組換え / 標的遺伝子組換え / T-DNA / 遺伝子脆弱部位 / ポリコーム遺伝子群 / rae28遺伝子 / Scmhl遺伝子 / ノックアウトマウス / 造血前駆細胞 / 造血幹細胞 / 形質転換動物 / 実験医学 / 遺伝性疾患モデル動物作製 / 形質転換性病態モデル動物 / アミロイド-シス / プレアルブミン / アミロイド / 常染色体性優性遺伝病 / 急性期反応 / cDNA / 遺伝子DNA / ペントラキシン / 急性期蛋白 / C反応性蛋白質 / 発癌プロモーター / 遺伝子発現 / マウステラトカルシノーマ細胞 / F9 / cDNAクローニング / 遺伝的組換え / 遺伝子のターゲッティング / 大腸菌 / 哺乳動物 / 遺伝子の人工的改変 / 改変遺伝子の各種細胞への導入 / キメラ個体の作成 / エンハンサー / SV40 / 転写調節 / 相同組換え / 高等真核生物 / DNA修復 / モデル動物 / 実験動物 / Rad51 / マウス / 細胞周期 / 高頻度相同組え系 / 酸母 / RAD51 / RAD52 / Homologous recombination / Higher eukaryotes / DNA repair / Experimantal Model animals / トランスサイレチン / ジーンターゲッティング / 胚幹細胞 / トランスサイレチン(プレアルブミン) / ジーンターゲティング / amyloidosis / transthyretin / mouse model of human disease / familial amyloidotic polyneuropathy / gene targeting / embryonic Stem cells / serum amyloid P component / transgenic mouse / アスパラギン酸トランスアミナーゼ / 酵素の構造と機能相関 / 部位特異的突然変異 / リンゴ酸・アスパラギン酸シャトル / アイソザイム遺伝子 / アイソザイムの発現調節 / 酵素の機構と機能相関 / リンゴ酸アスパラギン酸シヤトル / アイソザイム遺伝子の比較 / 酵素前駆体のミトコンドリヤ移入シグナル / アイソザイムの発現調節機構 / 酵素の構造機能相関 / アスパラギン酸・リンゴ酸シャトル / 哺乳動物酵素の酵母による発現 / リンゴ酸脱水素酵素 / トランスアミナーゼ / 酵素の構造と機能 / 酵素の発現調節機構 / Aspartate aminotransferase / Malate dehydrogenase / Malate-aspartate shuttle / Enzyme structure-function / Site-directed mutagenesis / Isozyme genes
Less
Research Projects
(
22
results)
Co-Researchers
(
54
People)
Project Start Year (Newest)
Project Start Year (Oldest)
マウスポリコーム遺伝子群による造血の維持と制御の分子機構の研究
Principal Investigator
瀧原 義宏
Project Period (FY)
1998
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Review Section
Biological Sciences
Research Institution
Osaka University
Regulation of organogenesis and hematopoiesis in development
Principal Investigator
Principal Investigator
SHIMADA Kazunori
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
Pathological medical chemistry
Research Institution
Osaka University
Study of CATCH22 syndorme using disease model mice
Principal Investigator
Principal Investigator
SHIMADA Kazunori
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Pathological medical chemistry
Research Institution
Osaka University
REGULATION OF MORPHOGENESIS IN EARLY MOUSE DEVELOPMENT
Principal Investigator
Principal Investigator
SHIMADA Kazunori
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for international Scientific Research
Research Field
General medical chemistry
Research Institution
Osaka University
Molecular Approach to an Amyloidosis by Using Gene Targeting
Principal Investigator
MAEDA Shuichiro
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
Yamanashi Medical University
GENERATION OF MOUSE MODELS FOR HUMAN GENETIC DISEASESTHROUGH GENE TARGETING
Principal Investigator
Principal Investigator
SHIMADA Kazunori
Project Period (FY)
1995 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Pathological medical chemistry
Research Institution
Osaka University
生理機能の発現と組換え機構
Principal Investigator
池田 日出男
Project Period (FY)
1993
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokyo
Use of embryonic stem cells to introduce mutations into mice
Principal Investigator
Principal Investigator
SHIMADA Kazunori
Project Period (FY)
1992 – 1994
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
Research Institute for Microbial Diseases, Osaka University
Construction of mouse model of human diseases by gene targeting
Principal Investigator
Principal Investigator
SHIMADA Kazunori
Project Period (FY)
1992 – 1994
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Pathological medical chemistry
Research Institution
Osaka University
細胞増殖を制御する新しいサイトカインLD78α、β、γの遺伝子構造と作用機構の研究
Principal Investigator
Principal Investigator
島田 和典
Project Period (FY)
1991
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Osaka University
染色体編成と人工染色体
Principal Investigator
柳田 充弘
Project Period (FY)
1991
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kyoto University
生理機能の発現と組換え機構
Principal Investigator
池田 日出男
Project Period (FY)
1991
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokyo
Establishiment of systems to produce experimental model animals using highly efficient homologous recombination
Principal Investigator
MATSUSHIRO Aizo
Project Period (FY)
1991 – 1993
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Laboratory animal science
Research Institution
Kinki University
Osaka University
細胞増殖に関与する新しいサイトカインLD78の分子生物学的研究
Principal Investigator
Principal Investigator
島田 和典
Project Period (FY)
1990
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Osaka University
Use of embryonic stem cell system to construct mouse model for human diseases
Principal Investigator
Principal Investigator
SHINADA Kazunori
Project Period (FY)
1989 – 1991
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
Osaka University
Kumamoto University
Regulatory expression of the mitochondrial and cytosolic isoenzyme genes participating in the malate-aspartate shuttle
Principal Investigator
Principal Investigator
SHIMADA Kazunori
Project Period (FY)
1989 – 1991
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
General medical chemistry
Research Institution
Osaka University
Kumamoto University
発癌プロモーターの刺激応答に関する分子生物学的研究
Principal Investigator
瀬戸山 千秋
Project Period (FY)
1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Kumamoto University
遺伝子の再編とその制御に関する基礎及び応用的研究
Principal Investigator
池田 日出男
Project Period (FY)
1988
Research Category
Grant-in-Aid for Co-operative Research (B)
Research Field
分子遺伝学・分子生理学
Research Institution
The University of Tokyo
Simian viras40ウィルスエンハンサーの活性調節機構
Principal Investigator
野見山 尚之
Project Period (FY)
1988
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kumamoto University
アミロイド-シスの発症機構と血清アミロイドP成分の関与に関する分子遺伝学的研究
Principal Investigator
MAEDA Shuichiro
Project Period (FY)
1987 – 1989
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Human genetics
Research Institution
Kumamoto University
実験医学領域における形質転換動物の応用
Principal Investigator
荻田 善一
Project Period (FY)
1986
Research Category
Grant-in-Aid for Co-operative Research (B)
Research Field
Human genetics
Research Institution
Toyama Medical and Pharmaceutical University
Molecular biology of aspartate aminotransferase isoenzymes and metabolically related enzymes in higher animals: Molecular basis of catalytic competence and regulatory mechanism of gene expression
Principal Investigator
MORINO Yoshimasa
Project Period (FY)
1985 – 1988
Research Category
Grant-in-Aid for Specially Promoted Research
Research Institution
Kumamoto University
# of Projects (Dsc)
# of Projects (Asc)
1.
TAKIHARA Yoshihiro
(60226967)
# of Collaborated Projects:
10 results
# of Collaborated Products:
0 results
2.
MAEDA Shuichiro
(10117244)
# of Collaborated Projects:
6 results
# of Collaborated Products:
0 results
3.
NISHIGUCHI Seiji
(90237686)
# of Collaborated Projects:
6 results
# of Collaborated Products:
0 results
4.
TOMOTSUNE Daihachiro
(80283802)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
5.
SETOYAMA Chiaki
(60040250)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
6.
NOMIYAMA Hisayuki
(00156225)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
7.
池田 日出男
(10012775)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
8.
大石 道夫
(00126004)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
9.
HIGASINAKAGAWA Toru
(70131935)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
10.
NOMURA Midori
(60263315)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
11.
駒野 照弥
(00087131)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
12.
川市 正史
(00195041)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
13.
續 輝久
(40155429)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
14.
GOTTESMAN Max E.
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
15.
BROCK Hugh W
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
16.
COSTANTINI F
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
17.
MATSUSHIRO Aizo
(00029753)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
MORITA Takashi
(70150349)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
JOH Tadashi
(50243259)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
SHIRAI Manabu
(70294121)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
MORINO Yoshimasa
(30028352)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
KAGAMIYAMA Hiroyuki
(80028555)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
柳田 充弘
(80025428)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
城石 俊彦
(90171058)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
榊 佳之
(10112327)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
大木 操
(00158792)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
山岸 秀夫
(90025429)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
28.
小林 泰夫
(10013319)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
29.
荻田 善一
(40109111)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
30.
松田 一郎
(10000986)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
31.
相沢 慎一
(60073011)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
32.
御子柴 克彦
(30051840)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
33.
山村 研一
(90115197)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
34.
大坪 英一
(10158800)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
35.
柴田 武彦
(70087550)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
36.
小川 英行
(70028207)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
37.
EPISKOPOU Vasso
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
38.
SARAIVA Maria.J.M
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
39.
HONDA Barry M
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
40.
池田 穰衛
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
41.
ROBERTSON El
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
42.
ROBERTSON Elizabeth
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
43.
COSTANTINI Franklin d.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
44.
CONSTANTINI エフ.ディー.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
45.
ROBERTSON E.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
46.
F D Constant
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
47.
E J Robertso
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
48.
MAX E Gottes
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
49.
BUXBAUM J.N.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
50.
GOTTESMAN M.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
51.
GOTTESMAN Max E
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
52.
COSTANTINI Franklin D
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
53.
BUXBAUM Joel N
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
54.
HODGSON Jaco
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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