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KAGAMIYAMA Hiroynki  鏡山 博行

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KAGAMIYAMA Hiroyuki  鏡山 博行

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Researcher Number 80028555
External Links
Affiliation (based on the past Project Information) *help 2003: Osaka Med. Col., Dept. Biochemistry, Professor, 医学部, 教授
1989 – 1998: 大阪医科大学, 医学部, 教授
1990 – 1992: 大阪医科大学, 教授
1986 – 1988: 大阪医科大学, 教授
Review Section/Research Field
Principal Investigator
General medical chemistry / 物質生物化学
Except Principal Investigator
Science and Engineering
Keywords
Principal Investigator
アスパラギン酸アミノ基転移酵素 / アミノ基転移酵素 / Aminotransferase / Protein Engineering / Active Site / Enzyme Mechanism / Aspartate Aminotransferase / Transaminase / 基質認識 / 酵素の活性中心 … More / ピリドキサル燐酸 / 部位特異的突然変異 / 酵素活性中心 / 酵素反応機構 / 蛋白質工学 / DNA shuffing / X-ray crystallography / Substrate recognition / Tryptophanase / Amino acid decarboxylase / Enzyme mechanism / Pyridoxal enzymes / アミノ-芳香環相互作用 / シッフ塩基 / イミノ基転移反応 / 分枝アミノ酸アミノ基転移酵素 / ピリドキサールリン酸 / 基質認識機構 / 芳香族アミノ酸脱炭酸酵素 / 分岐鎖アミノ酸アミノ基転移酵素 / 芳香族アミノ酸アミノ基転移酵素 / DNAシャフリング / X線結晶解析 / トリプトファナーゼ / アミノ酸脱炭酸酵素 / 酵素の反応機構 / ピリドキサール酵素 / Structure-Function Relationship / Pyridoxal Enzyme / B_6酵素 / 酵素の構造と機能 / タンパク質工学 / トランスアミナーゼ / ピリドキサル酵素 / 構造と機能相関 / Pyridoxal Phosphate / Mutagenesis / 活性中心 / 部位特異性突然変異 / ピリドキサルリン酸 / トランスアミナ-ゼ … More
Except Principal Investigator
テレンセファリン / 長期増強現象 / シナプス / pKa / アミノ基転移酵素 / 細胞接着分子 / 樹状突起 / 終脳 / Isozyme genes / Site-directed mutagenesis / Enzyme structure-function / Malate-aspartate shuttle / Malate dehydrogenase / Aspartate aminotransferase / 酵素の発現調節機構 / 酵素の構造と機能 / トランスアミナーゼ / リンゴ酸脱水素酵素 / 哺乳動物酵素の酵母による発現 / アスパラギン酸・リンゴ酸シャトル / 酵素の構造機能相関 / アイソザイムの発現調節機構 / 酵素前駆体のミトコンドリヤ移入シグナル / アイソザイム遺伝子の比較 / リンゴ酸アスパラギン酸シヤトル / 酵素の機構と機能相関 / アイソザイムの発現調節 / アイソザイム遺伝子 / リンゴ酸・アスパラギン酸シャトル / 部位特異的突然変異 / 酵素の構造と機能相関 / アスパラギン酸トランスアミナーゼ / composite-biocatalyst / transferase / stereochemistry / induced-fit / free-energy / catalytic-mechanism / proton-transfer / 歪み / ピリドキサールリン酸 / スフィンゴ脂質 / コンフォメーション / コンポジット触媒 / 転移酵素 / 立体化学 / 誘導適合 / 自由エネルギー / 触媒反応機構 / プロトン移動 / X-ray crystallography / Structure and function relationship / Substrate specificity / Catalytic activity / Amino acid substitution / Genetic engineering / Pyridoxal / Aminotransferse / ビタミンB6 / 酵素構造 / ピリドキサ-ル / アスパラギン酸 / X線結晶解析 / 機能構造相関 / 基質特異性 / 触媒機能 / アミノ酸残基置換 / 遺伝子工学 / ピリドキサール / 9 Protein Recognition / Protein Structure / Proteins / Brain / Micromachine / Bioclectronics / Biocomputer / Biochip / Biosensor / マイクロマシン / バイオコンピュ-タ- / バイオエレクトロニクス / バイオチップ / バイオセンサ- / 分子認識 / 高次構造 / 蛋白質 / 神経突起伸張促進作用 / ミクログリア / LFA-1 / 遺伝子欠損マウス / 樹状突起性細胞接着分子 / 海馬 / 神経可塑性 Less
  • Research Projects

    (10 results)
  • Co-Researchers

    (50 People)
  •  Designing composite biocatalysts by analysis of the proton-transfer process in pyridoxal enzymes

    • Principal Investigator
      HAYASHI Hideyuki
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Osaka Medical College
  •  終脳特異的樹状突起性細胞接着分子テレンセファリンのシナプス可塑性における役割

    • Principal Investigator
      吉原 良浩
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The Institute of Physical and Chemical Research
  •  終脳特異的樹状突起性細胞接着分子テレンセファリンのシナプス可塑性における役割

    • Principal Investigator
      吉原 良浩
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka Medical College
  •  終脳特異的樹状突起性細胞接着分子テレンセファリンのシナプス可塑性における役割

    • Principal Investigator
      吉原 良浩
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka Medical College
  •  Elucidation of mechanism for catalytic action of pyridoxal enzymesPrincipal Investigator

    • Principal Investigator
      KAGAMIYAMA Hiroyuki
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Osaka Medical College
  •  Studies on the mechanisms of substrate recognition and enzyme action in aspartate aminotransferasePrincipal Investigator

    • Principal Investigator
      KAGAMIYAMA Hiroyuki
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Osaka Medical College
  •  Japan-Germany/Japan-U. K. Cooperative Project on Bioscience with Special Reference to Protein Recognition

    • Principal Investigator
      TANIGUCHI Masaru
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  Structure and Function of Aspartate Aminotransferase

    • Principal Investigator
      MORINO Yoshimasa
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  Studies on Active Site of Transaminase by Site-Directed MutagenesisPrincipal Investigator

    • Principal Investigator
      KAGAMIYAMA Hiroyuki
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      Osaka Medical College
  •  Molecular biology of aspartate aminotransferase isoenzymes and metabolically related enzymes in higher animals: Molecular basis of catalytic competence and regulatory mechanism of gene expression

    • Principal Investigator
      MORINO Yoshimasa
    • Project Period (FY)
      1985 – 1988
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Research Institution
      Kumamoto University
  • 1.  吉原 良浩 (20220717)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  森 憲作 (60008563)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  MORINO Yoshimasa (30028352)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  YANO Takato (40239827)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  HAYASHI Hideyuki (00183913)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  KURAMITSU Seiki (60153368)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  KIRSCH J.F.
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  TANIGUCHI Masaru (80110310)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  WATANABE Takeshi (40028684)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ARATA Yoji (40011499)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  WAKABAYASHI Takeyuki (90011717)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  MORISHIMA Isao (50026093)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KAINOSHO Masatsune (20137029)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TAMIYA Eiichi (60179893)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KUBO Izumi (40214986)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  TOTANI Masayuki (70163988)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  UMEZAWA Yoshio (80011724)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  OSA Tetsuo (10010753)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  WATANABE Tadashi (70092385)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  SENDA Mitsugi (90026419)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  AIZAWA Masuto (00016742)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  SUZUKI Koichi (80011948)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  SUZUKI Akinori (90011907)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  KYOGOKU Yoshimasa (90012632)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  OHTSUKA Eiko (80028836)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  MATSUOKA Hideaki (10143653)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  KARUBE Isao (50089827)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  MATSUNAGA Tadashi (10134834)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  HIROTSU Ken (10047269)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  TANASE Sumio (20112401)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  MIZUGUCHI Hiroyuki (40247838)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  SHIMADA Kazunori (40037354)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  大井 龍夫 (00027012)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  渡辺 格 (10050858)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  二井 光将 (50012646)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  佐藤 生男 (20148125)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  伊藤 要 (50024196)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  米山 宏 (80029082)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  七里 元亮 (00028515)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  内山 俊一 (80129163)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  別府 輝彦 (80011873)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  山田 康之 (50026415)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  松原 謙一 (20037394)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  原田 宏 (90015991)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  樋口 泰一 (40046868)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  石井 誠志 (10247851)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  ARNONE A.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  METZLER D.E.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  TABATA Masayoshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  FUTAI Masamitsu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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