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MORISHIMA Isao  森島 績

ORCIDConnect your ORCID iD *help
… Alternative Names

森島 積  モリシマ イサオ

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Researcher Number 50026093
Affiliation (based on the past Project Information) *help 1995 – 2003: 京都大学, 工学研究科, 教授
1989 – 2000: 京都大学, 工学部, 教授
1999: 京都大学, 大学院・工学研究所, 教授
1999: 京都大学, 大学院・工学研究科, 教授
1996: Kyoto University, Engineering, Professor, 大学院・工学研究科, 教授 … More
1996: 京都大学大学院, 工学研究科, 教授
1994: 京都大学, 大学院・工学研究科, 教授
1994: 京都大学, 大学院・工学部, 教授
1994: Kyoto University, Faculty of Engineering.Professor, 工学研究科, 教授
1990: Graduate School of Engineering, Kyoto University, 工学部, 助教授
1986 – 1988: 京都大学, 工学部, 助教授
1986: 京大, 工学部, 助教授 Less
Review Section/Research Field
Principal Investigator
物理化学一般 / 広領域 / Biophysics / Inorganic chemistry / Chemistry / Structural biochemistry / 工業物理化学
Except Principal Investigator
Biophysics / 代謝生物化学 / Physical chemistry … More / 無機工業化学 / 無機・錯塩・放射化学 / 広領域 / Inorganic chemistry Less
Keywords
Principal Investigator
ヘム蛋白質 / 活性化体積 / ペルオキシターゼ / フェレドキシン / 亜硫酸還元酵素 / チトクロムP450 / モジュール / ミオグロビン / 高圧NMR / ヘムタンパク質 … More / 金属置換ミオグロビン / 光誘起電子移動 / アミノ酸置換蛋白質 / 配位子結合反応 / 酸素添加反応 / 電子伝達ヘム蛋白質 / チトクロームP450モデル / チトクロームP450変異体 / モジュール置換ヘモグロビン / チトクロームC3のミクロ構造 / 鉄イオウ蛋白質のモデル錯体 / パルスラジオリシス / 電子移動過程 / チトクロームC2の結晶構造 / 軸配位子置換 / P-450 / チトクロムc2 / チトクロムc3 / 鉄-硫黄蛋白質 / 鉄5価ポルフィリン / 金属蛋白質 / モジュール置換 / 電子移動 / 亜鉛置換ミオグロビン / レーザーフラッシュフォトリシス / チトクロムb5 / 電子移動複合体 / 揺らぎ / 高圧レーザーフラッシュフォトリシス / 高速混合装置 / 西洋ワサビペルオキシターゼ / Compound I / Compound 0 / 鉄オキソポルフィリンπカチオンラジカル / 蛋白質工学 / 生物物理学 / 生体分子 / 酵素 / 生物物理化学 / 分子設計 / アロステリック蛋白質 / カルシウム結合ループ / 酸素結合能 / モジュールライゲーション / ペプチドライゲーション / タンパク質分子設計 / ヘム交換反応 / ヘム反転反応 / NH / ND交換の圧力依存性 / 高圧レ-ザ-フォトリシス / 高圧分子分光法 / 高圧レーザーフォトリシス / 高圧下レーザーフラッシュフォトリシス / ヘモグロビン / 電子伝達 / レ-ザ-フォトリシス / Myoglobin / Hemoglobin / High-Pressure Kinetics / Laser Photolysis / Activation Volume / Ligand Binding / Electron Transfer / CO Rebinding / 亜硝酸還元酵素 / 蛋白質内電子伝達 / 酸素センサーFixL / チトクロム酸化酵素 / Peroxidase / Ferredoxin / Nitrite Reductase / Oxgen Snsor Fix L / Cytochrome c Oxidase / Cytochrome P450 / エクソンシャフリング / グロビン蛋白質 / エクソンジャフリング / Module / Exon Shaffling / Globin / 高圧多次元NMR / 高圧下フラッシュホトリシス / 蛋白質内電子伝達反応 / High Pressure Muiti-Nuclear NMR / High Presure Flash Photolysis / Hemoproteins / Electron Transfer in Proteins / 金属置換ヘムタンパク質 / モリブデン / タングステン置換ヘムタンパク質 / ニッケル置換ミオグロビン / ルテンウム置換ヘモグロビン / グリーンヘムタンパク質 / クロクン含有ヘムタンパク質 / 金属置換ヘム / ルテニウムヘム / モリブデンヘム / グリーンヘム蛋白 / 機能制御 / 分子工学 / Metal-substituted Hemoproteins / Molybdenum and Tungusten-substituted Hemoproteins … More
Except Principal Investigator
金属タンパク質 / Pー450_<14DM> / 生物無機化学 / 多重相互作用 / 生体関連金属錯体 / 金属酵素 / 蛋白質 / チトクロームPー450 / 部位特異的変異 / Pー450_<11β> / Pー450_<aldo> / 金属酵素モデル / 銅酵素 / 光合成系マンガン錯体 / 二酸化炭素固定 / NO合成酵素 / グアニレートシクラーゼ / 立体構造予測 / ダイナミックス / 生体エネルギー変換 / 生体情報変換 / プラチナ / 分子認識 / Proteins / タンパク質 / 人工変異タンパク質 / compound I / heme / cytochrome d / 固体触媒作用 / 半導体触媒 / 酸化物触媒 / 理論 / 電子状態 / ZnO / 吸着 / マデルングポテンシャル / P45011β / Pー450aldo / 副腎ミトコンドリア / Pー450cam / チトクロ-ムPー450 / 副腎皮質ミトコンドリア / Pー450_<cam> / 時間分解分光法 / 生体内反応の精密モデル化 / 学際的共同研究 / 反応速度制御 / ヘムタンパク質 / 酸素 / 酸素の活性化 / 活性酸素 / 酸素毒性 / チトクロムcオキシダ-ゼ / オキシゲナ-ゼ / チトクロムPー450 / ス-パ-オキシドアニオン / X線結晶構造解析 / ラウエ法 / 時間分割解析 / 蛋白質の構造 / 蛋白質の動的構造 / NMR分光法 / 緩和時間測定 / ケージ化合物 / NO-ヘム / チトクロムP-450 / 一酸化窒素 / 立体構造比較分類 / デザイン / 立体構造安定性 / 折れたたみ / 安定性 / チトクロム酸化酵素 / ペルオキシターゼ / 遺伝子発現制御 / 無機材料 / 電子論 / 触媒理論 / ダングリンボンド / 化学シフト / 生体系金属イオン / 配位環境 / 生体系モデル錯体 / 金属イオンの生理活性 / 機能性錯体 / 表面 / 化学吸着 / 触媒作用 / 銀 / Pー450 / Pー450_<C21> / Pー450_<17α、lyase> / アロマターゼ反応 / 高次構造 / バイオセンサ- / バイオチップ / バイオエレクトロニクス / バイオコンピュ-タ- / マイクロマシン / Biosensor / Biochip / Biocomputer / Bioclectronics / Micromachine / Brain / Protein Structure / 9 Protein Recognition / バイオマシン / 分光学 / MO計算 / 量子生物学 / 生体分子分光学 / 時間分解分光学 / Biomachine / Spectroscopy / MO calculation / Protein dynamics / 生体内反応過程 / 分子認識系 / 酸素運搬体 / 電子移動反応系 / 国際シンポジウム / DNA塩基認識 / 人工変異ヘムタンパク質 / Biological metal complex / Multiple interaction / Biological reaction process / Metalloenzyme model / Molecular recognition system / Oxygen carrier / Election transfer pathway / クロリン / カチオンラジカル / Cytochrome d / Compound I / 鉄クロリン錯体 / 酵素モデル / 酸素活性化 / 反応機構 / chlorin / cation radical / 進化分子工学 / 実験分子進化 / 試験管内分子進化 / 配列空間 / 適応歩行 / 適応度の地形 / モジュールシャフリング / 耐熱性酵素 / 競争的共存 / モジュールシャクリング / 耐熱化酵素 / 配列空間の適応歩行 / ウイルス型対応づけ / 高分子工学 / 階層的分子進化 / エクソンシャフリング / 耐熱静翼酵素 / キメラ蛋白 / EVOLUTIONARY MOLECULAR ENGINEERING / EXPERIMENTAL EVOLUTION / IN VITRO EVOLUTION / SEQUENCE SPACE / ADAPTIVE WALK / FITNESS LANDSCAPE / MODULE SHUFFLING / THERMOSTABILIZED ENZYME / 立体構造 / 構築原理 / 構造比較 / 構造予測 / 立体構造基本型 / スレッディング / モジュール / スレッティング / 立体構造比較 / 膜タンパク質 / ファージディスプレイ / キメラタンパク / リゾチウム / 構造分類 / モデリング / タンパク質デザイン / 相同蛋白質 / 膜蛋白質 / Protein / Three-dimensional structure / Principle of architecture / Structural comparison / Structural prediction / principal variety of protein folds / Threading / Module / 酸素結合蛋白質 / ヘモグロビン / ミオグロビン / 人工変異 / 分子分光学 / 分子進化 / 分子動力学 / Oxygen binding proteins / Hemoglobin / Myoglobin / Artificial mutation / Molecular spectroscopy / Molecular evolution / Molecular dynamics / 金属タンパク / 金属核酸錯体 / 小分子の活性化 / 光合成 / 生体分子科学 / 構造生物学 / 分子生物学 / 金属核酸 / 生体金属 / 生体エネルギー / 生体情報伝達 / 小分子活性化 / 生体無機化学 / Metallo-proteins / Metallo-nuclic acid / biometals / gene control / heme proteins / cytochromes / cytochrome oxidase / oxygen activation Less
  • Research Projects

    (36 results)
  • Co-Researchers

    (111 People)
  •  構造及び機能単位としてのモジュールを組み合わせた新規蛋白質の分子設計と創製Principal Investigator

    • Principal Investigator
      森島 績
    • Project Period (FY)
      2000 – 2003
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Chemistry
    • Research Institution
      Kyoto University
  •  生体金属による小分子の活性化Principal Investigator

    • Principal Investigator
      森島 績
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyoto University
  •  蛋白質構造の「揺らぎ」による電子移動過程の制御Principal Investigator

    • Principal Investigator
      森島 績
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biophysics
    • Research Institution
      Kyoto University
  •  金属酵素の不安定中間体を観測するための高速溶液混合実験システムの開発Principal Investigator

    • Principal Investigator
      森島 績
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Inorganic chemistry
    • Research Institution
      Kyoto University
  •  Molecular Science on the Specific Roles of Metal Ions in Biological Functions.

    • Principal Investigator
      KITAGAWA Teizo
    • Project Period (FY)
      1996 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okazaki National Research Institutes
  •  生体機能における金属イオンの特異的作用の分子科学

    • Principal Investigator
      北川 禎三
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Physical chemistry
    • Research Institution
      Okazaki National Research Institutes
  •  Protein structure, comparison, prediction, and design

    • Principal Investigator
      GO Nobuhiro, 野口 俊之
    • Project Period (FY)
      1995 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      KYOTO UNIVERSITY
      Nagoya University
  •  Molecular manipulation of oxygen binding proteins and new development of precise structure-function studies on them

    • Principal Investigator
      IMAI Kiyohiro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biophysics
    • Research Institution
      Osaka University
  •  Structural Regulation Mechanism for Reactivity in MetalloproteinsPrincipal Investigator

    • Principal Investigator
      MORISHIMA Isao
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      広領域
    • Research Institution
      KYOTO UNIVERSITY
  •  Protein Engineering for New Functional Hemoproteins Based on Module SubstitutionPrincipal Investigator

    • Principal Investigator
      MORISHIMA Isao
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      広領域
    • Research Institution
      KYOTO UNIVERSITY
  •  Developement and Application of High Pressure Multi-Dimensional NMR SpectroscopyPrincipal Investigator

    • Principal Investigator
      MORISHIMA Isao
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      KYOTO UNIVERSITY
  •  生体系におけるNOの合成と反応及びその検出

    • Principal Investigator
      北川 禎三
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Biophysics
    • Research Institution
      Okazaki National Research Institutes
  •  タンパク質立体構造の構築原理

    • Principal Investigator
      GO Nobuhiro
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Biophysics
    • Research Institution
      Kyoto University
  •  Studies on Structures and Specific Functions in Bioinoganic Chemistry

    • Principal Investigator
      YAMAUCHI Osamu
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  Adaptive design of biopolymers by evolutionary molecular engineering

    • Principal Investigator
      HUSIMI Yuzuru
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biophysics
    • Research Institution
      Saitama University
  •  金属蛋白質の多元的構造と反応過程制御Principal Investigator

    • Principal Investigator
      森島 績
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  時間分割ラウエ法利用研究

    • Principal Investigator
      三井 幸雄
    • Project Period (FY)
      1993 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagaoka University of Technology
  •  MECHANISM OF OXYGEN ACTIVATION BY IRON-CHLORIN COMPLEXES AND THEIR REACTIVITIES.

    • Principal Investigator
      WATANABE Yoshihito
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Inorganic chemistry
    • Research Institution
      OKAZAKI NATIONAL RESEARCH INSTITUTES
      Kyoto University
  •  生物無機化学における構造と特異機能の研究

    • Principal Investigator
      山内 脩
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  金属蛋白質の多元的構造と反応過程制御Principal Investigator

    • Principal Investigator
      森島 績
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  生体系における酸素活性化とその制御の分子機構

    • Principal Investigator
      石村 巽
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      代謝生物化学
    • Research Institution
      Keio University
  •  Structural and Functional Analysis of Hemoproteins Under High Pressure by Las Photolysis MeasurementsPrincipal Investigator

    • Principal Investigator
      MORISHIMA Isao
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物理化学一般
    • Research Institution
      KYOTO UNIVERSITY
  •  チトクロ-ムPー450の分子生物学・機能の分子機構

    • Principal Investigator
      石村 巽
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Keio University
  •  色素置換ヘム蛋白質における光電子移動反応の動的制御Principal Investigator

    • Principal Investigator
      森島 績
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  生物無機化学における構造と特異機能の研究

    • Principal Investigator
      YAMAUCHI Osamu
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Institution
      Nagoya University
  •  Japan-Germany/Japan-U. K. Cooperative Project on Bioscience with Special Reference to Protein Recognition

    • Principal Investigator
      TANIGUCHI Masaru
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  Quantum Theory and Spectroscopy of Proteins as Biomachines

    • Principal Investigator
      KITAGAWA Teizo
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      広領域
    • Research Institution
      Okazaki National Research Institutes, Institute for Molecular Science
  •  表面-分子相互作用系の電子状態とメカニズム解析

    • Principal Investigator
      中辻 博
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  チトクロームPー450の分子生物学:機能の分子機構

    • Principal Investigator
      石村 巽
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Keio University
  •  生体系金属イオンの配位環境と生理活性

    • Principal Investigator
      山内 脩
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      無機・錯塩・放射化学
    • Research Institution
      Nagoya University
  •  表面-分子相互作用系の電子状態とメカニズム解析

    • Principal Investigator
      中辻 博
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  チトクロームPー450の分子生物学:機能の分子機構

    • Principal Investigator
      石村 巽
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Keio University
  •  高圧NMR法によるタンパク質の動的構造の研究Principal Investigator

    • Principal Investigator
      森島 績
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Kyoto University
  •  高圧下におけるNMR、分子分光併用測定法の開発とその応用Principal Investigator

    • Principal Investigator
      森島 績
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      物理化学一般
    • Research Institution
      Kyoto University
  •  無機材料設計のための電子論

    • Principal Investigator
      YONEZAWA Teijiro
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      無機工業化学
    • Research Institution
      Kyoto University
  •  Studies on the Molecular Engineering of Functional Regulations of Synthetic Pigment Substituted HemoproteinsPrincipal Investigator

    • Principal Investigator
      MORISHIMA Isao
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      工業物理化学
    • Research Institution
      Kyoto University
  • 1.  KITAGAWA Teizo (40029955)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 2.  ISHIMORI Koichiro (20192487)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 3.  石村 巽 (40025599)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  NISHINO Takeshi (40094312)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  WATANABE Yoshihito (10201245)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  TAKAHASHI Satoshi (30283641)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 7.  YAMAUCHI Osamu (70029643)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 8.  SUZUKI Shinichiro (70116052)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 9.  GO Nobuhiro (50011549)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 10.  TANAKA Koji (00029274)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  MIKI Kunio (10116105)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  AKUTSU Hideo (60029965)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  中辻 博 (90026211)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
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  • 111.  FUTAI Masamitsu
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