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Kumagai Izumi  熊谷 泉

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KUMAGAI Izumi  熊谷 泉

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Researcher Number 10161689
Other IDs
External Links
Affiliation (Current) 2022: 東京農工大学, 工学(系)研究科(研究院), 客員教授
Affiliation (based on the past Project Information) *help 2019 – 2022: 東京農工大学, 工学(系)研究科(研究院), 客員教授
2013 – 2016: 東北大学, 大学院工学研究科, 名誉教授
2012: 東北大学, 大学院・工学研究科, 教授
2011 – 2012: 東北大学, 工学(系)研究科(研究院), 教授
1997 – 2010: TOHOKU UNIVERSITY,Faculty of Engineering, PROFESSOR, 大学院・工学研究科, 教授 … More
2007: Graduate School of Engineering, 大学院・工学研究科, Professor
2006: 東北大学, 大学院工学研究科, 教授
1995 – 1998: 東北大学, 工学部, 教授
1997: 東北大学, 大学院工学研究科, 教授
1993 – 1994: 東京大学, 工学部, 助教授
1992: 東京大学, 工学部
1989 – 1991: 東京大学, 工学部, 講師
1990: Univ. of Tokyo, Fac. of Engin., Ass. Professor, 工学部, 助教授
1990: 東京大学, 工学部・工業化学科, 助教授
1986 – 1988: 東京大学, 工学部, 助手
1986: 東大, 工学部, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Science and Engineering / Biofunction/Bioprocess / Molecular biology / Basic Section 50020:Tumor diagnostics and therapeutics-related / 物質生物化学 / 分子遺伝学・分子生理学 / Engineering / Laboratory medicine / 生物・生体工学 … More
Except Principal Investigator
… More Otorhinolaryngology / Biofunction/Bioprocess / 物質生物化学 / 結晶学 / Digestive surgery / Science and Engineering / 分子遺伝学・分子生理学 Less
Keywords
Principal Investigator
分子認識 / 抗体 / タンパク質工学 / 抗原抗体相互作用 / リゾチーム / α-ラクトアルブミン / X線結晶構造解析 / 結晶構造解析 / 二重特異性抗体 / 一本鎖抗体 … More / ANTIBODY / 遺伝子工学 / 構造解析 / 不溶性顆粒 / 巻き戻し系 / 熱力学的解析 / 蛋白質間相互作用 / 変異導入 / ファージ提示法 / 抗体工学 / ナノバイオ / 蛋白質 / バイオテクノロジー / タンパク質 / 繊維状ファージ / PROTEIN ENGINEERING / MOLECULAR RECOGNITION / αーラクトアルブミン / リゾチ-ム / 部位指定突然変異 / 機能性食品 / モノクローナル抗体 / 放線菌 / 放線菌スブチリシンインヒビター / 食品タンパク質 / キメラ受容体 / 細胞増殖 / 融合蛋白質 / 抗体-受容体キメラ蛋白質 / エリスロポエチン受容体 / 卷き戻し系 / TCR-HLA相互作用 / ILT-HLA相互作用 / 表面プラズモン共鳴 / 等温滴定型熱量測定 / 受容体 / 細胞性免疫 / 自然免疫 / T細胞受容体 / ヒト白血球抗原 / 抗原 / 特異性・親和性 / 熱力学 / 相補性 / バイオインターフェイス / ペプチド移植 / マテリアル認識抗体 / 酸化亜鉛認識抗体 / 金表面特異的抗体 / 高機能性非天然型抗体 / 無作為変異導入 / CDR移植 / マテリアル認識ペプチド / diabody / 非天然型組換え抗体 / ヒトFc受容体 / 親和性成熟 / 生細胞パニング / 非天然型抗体 / ナノ材料 / 細胞表面抗原 / Hot-Spot / ファージディスプレイ / EGFR / 低分子抗体 / 一本鎖体 / PEG化 / 多量体化 / 多価化 / 高機能性フォーマット / 化学修飾 / 酵母での分泌発現 / 生物機能工学 / FILAMENTOUS PHAGE / MORECULAR RECOGNITION / LYSOZYME / 一本抗体 / 血液検査 / 細胞凝集 / D抗原 / 多価 / 赤血球 / ヒト抗体 / ヒト赤血球 / 血液型 / 血球検査 / single-chain antibody / blood typing / agglutination / D antigen / multivalency / antibody engineering / red blood cell / human antibody / 無細胞生合成系 / 抗原特異性 / 蛋白質工学 / 進化工学 / 高原特異性 / CELL-FREE BIOSYNTHESIS SYSTEM / GENETIC ENGINEERING / ANTIGEN SPECIFICITY / EVOLUTIONARY ENGINEERING / 自己抗原 / 発現系 / 巻き戻しシステム / 蛋白性抗原 / 変異体 / 非共有結合 / PHAGE-DISPLAY SYSTEM / MUTAGENESIS / AUTOANTIGENS / CRYTAL STRUCTURE / EXPRESSION SYSTEM / REFOLDING SYSTEM / マルチスケール解析 / 次世代抗体設計 / クライオ電顕構造解析 / 構造モデリング … More
Except Principal Investigator
Prestin / 遺伝子工学 / コドン / 塩基組成 / 塩基置換 / 突然変異 / 遺伝暗号 / 変異圧 / 遺伝情報 / 膜タンパク質 / 原子間力顕微鏡 / メッセンジャーRNA(mRNA) / リボソーム / 遺伝子の情報発現 / 分子モータ / 国際研究者交流 / 耳科学 / タンパク質合成 / RNA / 転移RNA(tRNA) / 核酸の化学合成 / 蛋白工学 / プロテア-ゼ・インヒビタ- / Protein engineering / Protease inhibitor / タンパク質 / 立体構造 / 蛋白質 / Protein / SEA / Atomic force microscopy / 2次元結晶 / スイス / 抗体断片 / 金ナノ粒子 / センシング / アセンブリ / 遺伝性難聴 / ペンドリン / タンパク質フォールディング / Pendrin / リボ核酸 / タンパク質合成リボ核酸 / 酵素阻害剤 / 部位指定変異 / 放線菌 / 蛋白質の機能部位 / 蛋白質の構造 / Inhibitor / Site-directed mutagenesis / Streptomyces / Gene engineering / Active site of protein / Protein structure / プロテア-ゼ / 蛋白・蛋白相互作用 / 蛋白質工学 / X線解析 / 結晶構造 / 蛋白質の立体構造 / Protease / Protein-protein interaction / X-ray structure analysis / Crystal structure / Three-dimensional structure of Protein / 構築原理 / 構造比較 / 構造予測 / 立体構造基本型 / スレッディング / モジュール / スレッティング / 立体構造比較 / 立体構造予測 / ファージディスプレイ / キメラタンパク / リゾチウム / 構造分類 / モデリング / タンパク質デザイン / 相同蛋白質 / 膜蛋白質 / Three-dimensional structure / Principle of architecture / Structural comparison / Structural prediction / principal variety of protein folds / Threading / Module / タンパク質立体構造 / タンパク質の安定性 / タンパク質のダイナミックス / タンパク質の折れたたみ機構 / リゾチーム / カロリメトリー / X線結晶解析 / 安定性 / 折れたたみ機構 / 熱測定 / ダイナミックス / Protein Conformation / Stability of Protein / Dynamics of Protein / Protein Folding / Lysozyme / Calorimetry / X-ray crystal analyses / 養子免疫療法 / 胆管癌 / バイスペシフィク抗体 / MUC1 / MUSE11 / 一本鎖抗体 / MUC-1 / scFu / Bispecific抗体 / LAK細胞 / MVC1 / CD_3 / CD_<28> / Adoptive immunotherapy / Cholangiocarcinoma / Bispecific antibody / MUC 1 / MUSE 11 / single chain Fv / 外有毛細胞 / タンパク質モータ / 画像化 / Outer hari cell / Protein motor / Imaging / 精製 / 等温滴定カロリメトリー / 生物物理 / 走査プローブ顕微鏡 / パッチクランプ法 / 等温滴定型カロリメトリー / アメリカ / Otology / Molecular motor / Purification / Isothermal titration calorimetry / 真核細胞 / 遺伝情報発現の調節 / タンパク貭合成 / protein synthesis / messenger RNA (mRNA) / ribosome / gene expression / eukaryote Less
  • Research Projects

    (34 results)
  • Research Products

    (207 results)
  • Co-Researchers

    (69 People)
  •  高活性二重特異性抗体の創製に資する至適な抗原配置の先端的構造解析による描像Principal Investigator

    • Principal Investigator
      熊谷 泉
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Tokyo University of Agriculture and Technology
  •  Consideration on the high activation mechanism of bispecific antibodies by multi-scale analysis for the design of next-generation antibodiesPrincipal Investigator

    • Principal Investigator
      Kumagai Izumi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Tokyo University of Agriculture and Technology
  •  Bio-design for interface molecules in nano scalePrincipal Investigator

    • Principal Investigator
      KUMAGAI IZUMI
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Science and Engineering
      Engineering
    • Research Institution
      Tohoku University
  •  ナノ世界のインターフェイス構築へのタンパク質工学的デザイン学Principal Investigator

    • Principal Investigator
      熊谷 泉
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Biofunction/Bioprocess
    • Research Institution
      Tohoku University
  •  EGFR陽性がんの標的治療を目指す低分子抗体の創製Principal Investigator

    • Principal Investigator
      熊谷 泉
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Creation of a New Method to Refold the Membrane Protein Mutants for Curing of Hereditary Hearing Loss

    • Principal Investigator
      WADA Hiroshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tohoku University
  •  金材料特異的抗体から発想される革新的ワンポット蛋白質ネットワークアッセイ

    • Principal Investigator
      梅津 光央
    • Project Period (FY)
      2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biofunction/Bioprocess
    • Research Institution
      Tohoku University
  •  プレスチン結晶化の試み〜聴覚を鋭敏にしているモーター蛋白質の構造解明を目指して〜

    • Principal Investigator
      WADA Hiroshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tohoku University
  •  Structural and functional analysis of the motor protein prestin using purified protein

    • Principal Investigator
      WADA Hiroshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tohoku University
  •  抗原抗体反応における特異性・親和性創出と水分子との関連に関する実験的考察Principal Investigator

    • Principal Investigator
      熊谷 泉
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Tohoku University
  •  Protein Engineering for Construction of Bio-interfacesPrincipal Investigator

    • Principal Investigator
      KUMAGAI Izumi
    • Project Period (FY)
      2004 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Biofunction/Bioprocess
    • Research Institution
      Tohoku University
  •  Structural analysis of the motor protein prestin

    • Principal Investigator
      WADA Hiroshi
    • Project Period (FY)
      2003 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Tohoku University
  •  構造情報に基づく細胞性免疫システムにおける特異的分子認識機構の解明Principal Investigator

    • Principal Investigator
      熊谷 泉
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  GENERATION AND UTILIZATION OF NOVEL HUMAN ANTIBODY MOLECULES BASED ON GENETIC INFORMATIONPrincipal Investigator

    • Principal Investigator
      KUMAGAI Izumi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      生物・生体工学
    • Research Institution
      Tohoku University
  •  シグナル伝達機構解析を目指した抗体-受容体キメラ蛋白質の創製と構造解析Principal Investigator

    • Principal Investigator
      熊谷 泉
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  新機能抗体-受容体キメラ蛋白質の創製と細胞増殖制御機構解析への応用Principal Investigator

    • Principal Investigator
      熊谷 泉
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  CELL-FREE BIOSYNTHESIS SYSTEM OF NOVEL ANTIBODIESPrincipal Investigator

    • Principal Investigator
      KUMAGAI Izumi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Molecular biology
    • Research Institution
      TOHOKU UNIVERSITY
  •  Establishment of the adoptive anticancer immunotherapy for the unresectable cholangiocarcinoma using the bispecific antibody - Construction of bacterial expression system of bispecific antibodies

    • Principal Investigator
      SUZUKI Masanori
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      TOHOKU UNIVERSITY
  •  Protein structure, comparison, prediction, and design

    • Principal Investigator
      GO Nobuhiro, 野口 俊之
    • Project Period (FY)
      1995 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      KYOTO UNIVERSITY
      Nagoya University
  •  タンパク質立体構造の安定性・ダイナミックス・折れたたみ機構

    • Principal Investigator
      YUTANI Katsuhide
    • Project Period (FY)
      1995 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      OSAKA UNIVERSITY
  •  GENERATION OF HUMAN ANTIBODIES SPECIFIC FOR HUMAN CELL SURFACE ANTIGENS BY GENETIC ENGINEERINGPrincipal Investigator

    • Principal Investigator
      KUMAGAI Izumi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory medicine
    • Research Institution
      TOHOKU UNIVERSITY
  •  PROTEIN ENGINEERING OF ANTIBODIES FOR CREATING NOVEL MOLECULAR RECOGNITION PROPERTIES INTO AN ANTIBODYPrincipal Investigator

    • Principal Investigator
      KUMAGAI Izumi
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Molecular biology
    • Research Institution
      TOHOKU UNIVERSITY
      The University of Tokyo
  •  タンパク質工学による食品タンパク質の機能設計Principal Investigator

    • Principal Investigator
      熊谷 泉
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  タンパク質工学による食品タンパク質の機能設計Principal Investigator

    • Principal Investigator
      熊谷 泉
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  酵素機能実現を目指したαーラクトアルブミンの遺伝子工学的改変Principal Investigator

    • Principal Investigator
      熊谷 泉
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      物質生物化学
    • Research Institution
      The University of Tokyo
  •  コドン選択

    • Principal Investigator
      池村 淑道
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      National Institute of Genetics
  •  コドン選択

    • Principal Investigator
      池村 淑道
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      National Institute of Genetics
  •  コドン選択

    • Principal Investigator
      池村 淑道
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      National Institute of Genetics
  •  Alteration of Structure and Function of Protease Inhibitor SSI to Design a New Enzyme Inhibitor

    • Principal Investigator
      MIURA Kin-ichiro
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      The University of Tokyo
  •  Crystallographic Studies on Protease ー Substrate Interaction Using Genetically - Engineered Inhibitors.

    • Principal Investigator
      MITSUI Yukio
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      結晶学
    • Research Institution
      Nagaoka University of Technology
  •  人工的タンパク質合成系の研究

    • Principal Investigator
      MIURA Kin-ichiro
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      The University of Tokyo
  •  乳蛋白質,α-ラクトアルブミンの異種細胞での発現系の確立Principal Investigator

    • Principal Investigator
      熊谷 泉
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      分子遺伝学・分子生理学
    • Research Institution
      The University of Tokyo
  •  人工的タンパク質合成系の研究

    • Principal Investigator
      三浦 謹一郎
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      The University of Tokyo
  •  Relationship between efficiency of protein synthesis and structure of messenger RNA

    • Principal Investigator
      MIURA Kin-ichiro
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      分子遺伝学・分子生理学
    • Research Institution
      The University of Tokyo, Faculty of Engineering

All 2022 2021 2020 2019 2017 2016 2015 2014 2013 2012 2010 2009 2008 2007 2006 2005 2004

All Journal Article Presentation Book Patent

  • [Book] がん免疫療法への応用研究を目指した抗体-diabody-とシーズ2009

    • Author(s)
      浅野竜太郎, 熊谷泉
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Book] 抗体ドメインの積み木細工による高機能化と医用への展開, 抗体医薬の最前線2007

    • Author(s)
      熊谷泉, 浅野竜太郎, 中西猛
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Book] 抗体ドメインの積み木細工による高機能化と医用への展開(抗体医薬の最前線)2007

    • Author(s)
      熊谷 泉
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Book] 蛋白質科学(担当部分;抗体のファージディスプレイ・リボゾームディスプレイ)2005

    • Author(s)
      熊谷 泉
    • Total Pages
      579
    • Publisher
      化学同人
    • Data Source
      KAKENHI-PROJECT-16041204
  • [Book] 蛋白質科学(担当部分;抗体のファージディスプレイ・リボゾームディスプレイ)2005

    • Author(s)
      熊谷 泉
    • Total Pages
      579
    • Publisher
      化学同人
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] 低分子型二重特異性抗体の高機能化戦略2022

    • Author(s)
      浅野竜太郎, 熊谷 泉
    • Journal Title

      バイオサイエンスとインダストリー

      Volume: 80 (1) Pages: 40-41

    • Data Source
      KAKENHI-PROJECT-19H03511
  • [Journal Article] Evaluation of intercellular cross-linking abilities correlated with cytotoxicities of bispecific antibodies with domain rearrangements using AFM force-sensing2021

    • Author(s)
      Maejima A., Ishibashi K., Kim H., Kumagai I., Asano R.
    • Journal Title

      Biosensors and Bioelectronics

      Volume: 178 Pages: 113037-113037

    • DOI

      10.1016/j.bios.2021.113037

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03511, KAKENHI-PROJECT-21K18321, KAKENHI-PROJECT-19KK0194
  • [Journal Article] 二重特異性がん治療抗体の機能的な構造の理解に向けたあゆみ2021

    • Author(s)
      浅野竜太郎, 真壁幸樹, 田中良和, 熊谷 泉
    • Journal Title

      医学のあゆみ

      Volume: 278 (6) Pages: 617-622

    • Data Source
      KAKENHI-PROJECT-19H03511
  • [Journal Article] Anti-EGFR antibody 528 binds to domain III of EGFR at a site shifted from the cetuximab epitope2021

    • Author(s)
      Makabe Koki、Yokoyama Takeshi、Uehara Shiro、Uchikubo-Kamo Tomomi、Shirouzu Mikako、Kimura Kouki、Tsumoto Kouhei、Asano Ryutaro、Tanaka Yoshikazu、Kumagai Izumi
    • Journal Title

      Scientific Reports

      Volume: 11 Pages: 1-1

    • DOI

      10.1038/s41598-021-84171-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19KK0178, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-19H02519, KAKENHI-PROJECT-19H03511, KAKENHI-PROJECT-20H02534
  • [Journal Article] Functional Domain Order of an Anti-EGFR × Anti-CD16 Bispecific Diabody Involving NK Cell Activation2020

    • Author(s)
      Kuwahara Atsushi、Nagai Keisuke、Nakanishi Takeshi、Kumagai Izumi、Asano Ryutaro
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Pages: 8914-8914

    • DOI

      10.3390/ijms21238914

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19KK0194, KAKENHI-PROJECT-19H03511, KAKENHI-PROJECT-20H02534
  • [Journal Article] Construction of a circularly connected VHH bispecific antibody (cyclobody) for the desirable positioning of antigen-binding sites.2020

    • Author(s)
      Hemmi S, Asano R, Kimura K, Umetsu M, TNakanishi T, Kumagai I, Makabe K.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 523(1) Pages: 72-77

    • DOI

      10.1016/j.bbrc.2019.12.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19KK0194, KAKENHI-PROJECT-17K08368, KAKENHI-PROJECT-19H03511
  • [Journal Article] Association behavior and control of the quality of cancer therapeutic bispecific diabodies expressed in Escherichia coli2020

    • Author(s)
      Hikaru Nakazawa, Tomoko Onodera-Sugano, Aruto Sugiyama, Yoshikazu Tanaka, Takamitsu Hattori, Teppei Niide, Hiromi Ogata, Ryutaro Asano, Izumi Kumagai, Mitsuo Umetsu
    • Journal Title

      Biochemical Engineering Journal

      Volume: 160 Pages: 107636-107636

    • DOI

      10.1016/j.bej.2020.107636

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K04842, KAKENHI-PROJECT-18K14059, KAKENHI-PROJECT-19H03511, KAKENHI-PROJECT-20H02534
  • [Journal Article] Build-up functionalization of anti-EGFR × anti-CD3 bispecific diabodies by integrating high-affinity mutants and functional molecular formats.2020

    • Author(s)
      Asano R, Hosokawa K, Taki S, Konno S, Shimomura I, Ogata H, Okada M, Arai K, Nakanishi T, Onitsuka M, Omasa T, Umetsu M, Kumagai I.
    • Journal Title

      Scientific Reports

      Volume: 10(1) Pages: 4913-4913

    • DOI

      10.1038/s41598-020-61840-3

    • NAID

      120007141559

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19KK0194, KAKENHI-PROJECT-17K08368, KAKENHI-PROJECT-19H03511
  • [Journal Article] Chemically crosslinked bispecific antibodies for cancer therapy: Breaking from the structural restrictions of the genetic fusion approach.2020

    • Author(s)
      Ueda Asami, Umetsu Mitsuo, Nakanishi Takeshi, Hashikami Kentaro, Nakazawa Hikaru, Hattori Shuhei, Asano Ryutaro, Kumagai Izumi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Pages: 711-711

    • DOI

      10.3390/ijms21030711

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K04842, KAKENHI-PROJECT-17K08368, KAKENHI-PROJECT-19H03511
  • [Journal Article] A semi high-throughput method for screening small bispecific antibodies with high cytotoxicity2017

    • Author(s)
      Aruto Sugiyama, Mitsuo Umetsu, Hikaru Nakazawa, Teppei Niide, Tomoko Onodera, Katsuhiro Hosokawa, Shuhei Hattori, Ryutaro Asano, and Izumi Kumagai
    • Journal Title

      Scientific Reports

    • Description
      【掲載確定】 印刷中
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Journal Article] Generation of camelid VHH bispecific constructs via in-cell intein-mediated protein trans-splicing.2017

    • Author(s)
      Shibuya Y, Haga N, Asano R, Nakazawa H, Hattori T, Takeda D, Sugiyama A, Kurotani R, Kumagai I, Umetsu M, Makabe K.
    • Journal Title

      Protein Eng Des Sel.

      Volume: 30 Pages: 15-21

    • DOI

      10.1093/protein/gzw057

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16J04866, KAKENHI-PROJECT-16K14483, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-16K18296, KAKENHI-PROJECT-16H04570, KAKENHI-PROJECT-15K09208
  • [Journal Article] Anti-EGFR scFv tetramer (tetrabody) with a stable monodisperse structure, strong anticancer effect, and long in vivo half-life2016

    • Author(s)
      Ryutaro Asano, Noriaki Koyama, Yasuyo Hagiwara, Yosuke Masakari, Ryota Orimo, Kyoko Arai, Hitomi Ogata, Shozo Furumoto, Mitsuo Umetsu, and Izumi Kumagai
    • Journal Title

      FEBS Open Bio

      Volume: 6 Pages: 594-598

    • DOI

      10.1002/2211-5463.12073

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Journal Article] 人工改変を駆使した高機能性次世代がん治療抗体の開発2016

    • Author(s)
      浅野 竜太郎, 熊谷 泉
    • Journal Title

      ファインケミカル

      Volume: 46 Pages: 13-18

    • Data Source
      KAKENHI-PROJECT-24000011
  • [Journal Article] Zine Ion-binding Activity of an Anti-ZnO VHH Antibody, 4F22015

    • Author(s)
      Ryosuke Sasaki, Soichiro Kitazawa, Ryo Kitahara, Hikaru Nakazawa, Yoshikazu Tanaka, Izumi Kumagai, Mitsuo Umetsu, Koki Makabe
    • Journal Title

      Chemistry Letters

      Volume: 44 Issue: 10 Pages: 1309-1311

    • DOI

      10.1246/cl.150537

    • NAID

      130005101454

    • ISSN
      0366-7022, 1348-0715
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26670051, KAKENHI-PROJECT-25840025, KAKENHI-PROJECT-24000011
  • [Journal Article] Microtubule guiding in a multi-walled carbon nanotube circuit2015

    • Author(s)
      Aurélien Sikora, Javier Ramón-Azcón, Mustafa Sen, Kyongwan Kim, Hikaru Nakazawa, Mitsuo Umetsu, Izumi Kumagai, Hitoshi Shiku, Tomokazu Matsue, Winfried Teizer
    • Journal Title

      Biomedical Microdevices

      Volume: 17

    • DOI

      10.1007/s10544-015-9978-1

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25289290, KAKENHI-PROJECT-24000011
  • [Journal Article] Behavior of Kinesin Driven Quantum Dots Trapped in a Microtubule Loop2015

    • Author(s)
      Aurelien Sikora, Filippo Federici Canova, Kyongwan Kim, Hikaru Nakazawa, Mitsuo Umetsu, Izumi Kumagai, Tadafumi Adschiri, Wonmuk Hwang, Winfried Teizer
    • Journal Title

      ACS Nano

      Volume: 9 Pages: 11003-11013

    • DOI

      10.1021/acsnano.5b04348

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25289290, KAKENHI-PROJECT-24000011
  • [Journal Article] Organic crystal-binding peptide : Morphology control and one-pot formation of protein-displaying organic crystals2015

    • Author(s)
      Teppei Niide, Kyohei Ozawa, Hikaru Nakazawa, Oliveira Daniel, Hitoshi Kasai, Mari Onodera, Ryutaro Asano, Izumi Kumagai, Mitsuo Umetsu
    • Journal Title

      Nanoscale

      Volume: 7 Pages: 20155-20163

    • DOI

      10.1039/c5nr06471f

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25248044, KAKENHI-PROJECT-25289290, KAKENHI-PROJECT-24000011
  • [Journal Article] Glycosylation analysis of an aggregated antibody produced by Chinese hamster ovary cells in bioreactor culture2014

    • Author(s)
      Masayoshi Onitsuka, Akira Kawaguchi, Ryutaro Asano, Izumi Kumagai, Kohsuke Honda, Hisao Ohtake, Takeshi Omasa
    • Journal Title

      Journal of Bioscience and Bioengineering

      Volume: 117 Issue: 5 Pages: 639-644

    • DOI

      10.1016/j.jbiosc.2013.11.001

    • NAID

      110009823143

    • ISSN
      1389-1723
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25640085, KAKENHI-PROJECT-26249125
  • [Journal Article] タンパク質工学を駆使した高機能性二重特異性抗体の開発2014

    • Author(s)
      浅野竜太郎, 熊谷泉
    • Journal Title

      生化学

      Volume: 86 Pages: 469-473

    • NAID

      40020200967

    • Data Source
      KAKENHI-PROJECT-24000011
  • [Journal Article] Trehalose suppresses antibody aggregation during the culture of Chinese hamster ovary cells2014

    • Author(s)
      Masayoshi Onitsuka et al.
    • Journal Title

      Journal of Bioscience and Bioengineering

      Volume: 117 Issue: 5 Pages: 632-638

    • DOI

      10.1016/j.jbiosc.2013.10.022

    • NAID

      110009823142

    • ISSN
      1389-1723
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23686118, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25870476, KAKENHI-PROJECT-26630433
  • [Journal Article] Molecular Motor-Powered Shuttles along Multi-walled Carbon Nanotube Tracks2014

    • Author(s)
      Aurélien Sikora, Javier Ramón-Azcón, Kyongwan Kim, Kelley Reaves, Hikaru Nakazawa, Mitsuo Umetsu, Izumi Kumagai, Tadafumi Adschiri, Hitoshi Shiku, Tomokazu Matsue, Wonmuk Hwang, Winfried Teizer
    • Journal Title

      Nano Letters

      Volume: 14 Pages: 876-881

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Journal Article] Rearranging the domain order of a diabody-based IgG-like bispecificantibody enhances its antitumor activity and improves its degradation resistance and pharmacokinetics2014

    • Author(s)
      Ryutaro Asano et al.
    • Journal Title

      Mabs

      Volume: 6 Pages: 1243-1254

    • DOI

      10.4161/mabs.29445

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23686118, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25640085
  • [Journal Article] 新規巻き戻し法による標的タンパク質の調製―完全変性を経由しない巻き戻し法―2013

    • Author(s)
      梅津 光央、熊谷 泉
    • Journal Title

      BIO INDUSTRY

      Volume: 30 Pages: 29-39

    • Data Source
      KAKENHI-PROJECT-24000011
  • [Journal Article] Hybrid Nanocellulosome Design from Cellulase Modules on Nanoparticles: Synergistic Effect of Catalytically Divergent Cellulase Modules on Cellulose Degradation Activity2013

    • Author(s)
      Hikaru Nakazawa, Do-Myoung Kim, Takeshi Matsuyama, Nobuhiro Ishida, Akinori Ikeuchi, Yuri Ishigaki, Izumi Kumagai, Mitsuo Umetsu
    • Journal Title

      ACS Catalysis

      Volume: 3 Pages: 1342-1348

    • DOI

      10.1021/cs400012v

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-24656496, KAKENHI-PROJECT-25289290
  • [Journal Article] Development of an affinity-matured humanized anti-epidermal growth factor receptor antibody for cancer immunotherapy2013

    • Author(s)
      Takeshi Nakanishi, et al.
    • Journal Title

      Protein Engineering, Design & Selection

      Volume: 26 Pages: 113-122

    • DOI

      10.1093/protein/gzs088

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23686118, KAKENHI-PROJECT-23790136, KAKENHI-PROJECT-24000011
  • [Journal Article] Multimerization of anti-(epidermal growth factor receptor) IgG fragments induces an antitumor effect : the case for humanized 528 scFv multimers2013

    • Author(s)
      Ryutaro Asano, el al.
    • Journal Title

      FEBS Journal

      Volume: 280 Pages: 4816-4826

    • DOI

      10.1111/febs.12451

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23686118, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25640085
  • [Journal Article] Domain order of a bispecific diabody dramatically enhances its antitumor activity beyond structural format conversion: the case of the hEx3 diabody.2013

    • Author(s)
      Ryutaro Asano, el al.
    • Journal Title

      Protein Engineering Design and Selection

      Volume: 26 Pages: 359-367

    • DOI

      10.1093/protein/gzt009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23686118, KAKENHI-PROJECT-23791512, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25420836, KAKENHI-PROJECT-25640085
  • [Journal Article] In-one-pot-at-a-time Ligation for High-throughput Construction of a Protein Expression Vector Library2013

    • Author(s)
      Hikaru Nakazawa, Rui Todokoro, Yuri Ishigaki, Izumi Kumagai, Mitsuo Umetsu
    • Journal Title

      Chemistry letters

      Volume: 42 Pages: 424-426

    • NAID

      10031162195

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Journal Article] Application of 300× Enhanced Fluorescence on a Plasmonic Chip Modified with a Bispecific Antibody to a Sensitive Immunosensor2013

    • Author(s)
      Keiko Tawa, Mitsuo Umetsu, Hikaru Nakazawa, Takamitsu Hattori, Izumi Kumagai
    • Journal Title

      ACS Appl. Mater. Interfaces

      Volume: 5 Pages: 8628-8632

    • DOI

      10.1021/am402173y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-24656496, KAKENHI-PROJECT-25286032, KAKENHI-PROJECT-25289290
  • [Journal Article] Rapid and sensitive detection of brain-derived neurotrophic factor (BDNF) with a plasmonic chip2013

    • Author(s)
      Keiko Tawa, Mari Satoh, Koichi Uegaki, Tomoko Hara, Masami Kojima, Hiroyuki Aota, Yoshiki Yokota, Takahiko Nakaoki, Mitsuo Umetsu, Hikaru Nakazawa, Izumi Kumagai
    • Journal Title

      Jpn. J. Appl. Phys.

      Volume: 52 Issue: 6S Pages: 06GK01-06GK01

    • DOI

      10.7567/jjap.52.06gk01

    • NAID

      210000142391

    • ISSN
      0021-4922, 1347-4065
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-24656496, KAKENHI-PROJECT-25286032
  • [Journal Article] Biomass-binding peptides designed by molecular evolution for efficient degradation of cellulose in biomass by cellulase2013

    • Author(s)
      Hikaru Nakazawa, Akinori Ikeuchi, Do-Myoung Kim, Yuri Ishigaki, Hidetaka Asano, Katsunori Kouda, Izumi Kumagai, Mitsuo Umetsu
    • Journal Title

      Green Chemistry

      Volume: 15 Pages: 365-369

    • DOI

      10.1039/c2gc36914a

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-24656496, KAKENHI-PROJECT-25289290
  • [Journal Article] The assembly of kinesin-based nanotransport systems2012

    • Author(s)
      D. Oliveira, D.-M. Kim, M. Umetsu, I. Kumagai, T. Adschiri, W. Teizer
    • Journal Title

      Journal of Applied Physics

      Volume: 112

    • DOI

      10.1063/1.4769870

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12F02072, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-24656496
  • [Journal Article] ボトムアップな粒子アセンブリツールとしてのバイオ分子2012

    • Author(s)
      梅津 光央、熊谷 泉
    • Journal Title

      セラミックス

      Volume: 47 Pages: 616-619

    • NAID

      10031155593

    • Data Source
      KAKENHI-PROJECT-24000011
  • [Journal Article] A high-affinity gold-binding camel antibody: Antibody engineering2012

    • Author(s)
      Takamitsu Hattori, Mitsuo Umetsu, Takeshi Nakanishi, Satoko Sawai, Shinsuke Kikuchi, Ryutaro Asano, and Izumi Kumagai
    • Journal Title

      Bioconjugate Chemistry

      Volume: 23(9) Pages: 1934-1944

    • DOI

      10.1021/bc300316p

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310076, KAKENHI-PROJECT-23686118, KAKENHI-PROJECT-23790136, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-24656496
  • [Journal Article] ナノ材料も抗原?ポリマー・金属表面構造を識別できる抗体分子2010

    • Author(s)
      熊谷泉
    • Journal Title

      月刊「化学」

      Volume: 65 Pages: 66-67

    • Data Source
      KAKENHI-PROJECT-22226013
  • [Journal Article] Integration of PEGylation and refolding for renaturation of recombinant proteins from insoluble aggregates produced in bacteria-Application to a single-chain Fv fragment2010

    • Author(s)
      Izumi Kumagai
    • Journal Title

      Journal of Bioscience and Bioengineering (未定, 印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015004
  • [Journal Article] Salicylate-induced translocation of prestin having mutation in the GTSRH sequence to the plasma membrane2010

    • Author(s)
      Kumano S, Iida K, Ishihara K, Murakoshi M, Tsumoto K, Ikeda K, Kumagai I, Kobayashi T, Wada H
    • Journal Title

      FEBS Lett. 584

      Pages: 2327-2332

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390439
  • [Journal Article] Integration of PEGylation and refolding for renaturation of recombinant proteins from insoluble aggregates produced in bacteria--application to a single-chain Fv fragment2010

    • Author(s)
      Izumi Kumagai
    • Journal Title

      Journal of Bioscience and Bioengineering

      Volume: 109 Pages: 447-452

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22226013
  • [Journal Article] 次世代抗体医薬の分子設計2009

    • Author(s)
      熊谷泉, 浅野竜太郎
    • Journal Title

      ケミカルエンジニヤリング 54

      Pages: 65-71

    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] 次世代抗体医薬の分子設計2009

    • Author(s)
      熊谷泉
    • Journal Title

      ケミカルエンジニヤリング 54

      Pages: 65-71

    • Data Source
      KAKENHI-PROJECT-20015004
  • [Journal Article] 次世代抗体医薬の分子設計2009

    • Author(s)
      熊谷泉
    • Journal Title

      ケミカルエンジニヤリング 54

      Pages: 65-71

    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Human Anti-gold Antibodies : BIOFUNCTIONALIZATGOLD NANOPARTICLES AND SURFACES WITH ANTI-GOLD ANTIBODIES.2008

    • Author(s)
      Watanabe H., Nakanishi T., Umetsu M., Kumagai I.
    • Journal Title

      J. Biol. Chem., 283

      Pages: 36031-36038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Critical Contribution of VH-VL Interaction to Reshaping of an Antibody : The case of humanization of anti-lysozyme antibody, HyHEL-102008

    • Author(s)
      Nakanishi T., Tsumoto K., Yokota A., Kondo H., Kumagai I.
    • Journal Title

      Protein Sci. 17

      Pages: 261-270

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Critical contribution of aromatic rings to specific recognition of polyether rings. The case of ciguatoxin CTX3C-ABC and its specific antibody 1C492008

    • Author(s)
      Tsumoto K., Yokota A., Tanaka Y., Ui M., Tsumuraya T., Fujii I., Kumagai I., Nagumo Y., Oguri H., Inoue M., Hirama M.
    • Journal Title

      J. Biol. Chem. 283

      Pages: 12259-12266

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Grafting of material-binding function into antibodies Functionalization by peptide grafting2008

    • Author(s)
      Hattori T., Umetsu M., Nakanishi T., Tsumoto K., Ohara S., Abe H., Naito M.,Asano R., Adschiri T., Kumagai I.
    • Journal Title

      Biochem. Biophys. Res. Commun. 365

      Pages: 751-757

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Diabody-based recombinant formats of humanized IgG-like bispecific antibody with effective retargeting of lymphocytes to tumor cells2008

    • Author(s)
      Asano R., Kawaguchi H., Watanabe Y., Nakanishi T., Umetsu M., Hayashi H., Katayose Y., Unno M., Kudo T., Kumagai I.
    • Journal Title

      J. Immunother. 31

      Pages: 752-761

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] リンパ球とがん細胞を認識するヒト型二重特異性抗体2008

    • Author(s)
      熊谷泉
    • Journal Title

      Drug Delivery System 23

      Pages: 518-525

    • NAID

      10024309899

    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Purification of the motor protein prestin from Chinese hamster ovary cells stably expressing prestin2008

    • Author(s)
      Iida K, Murakoshi M, Kumano S, Tsumoto K, Ikeda K, Kobayashi T, Kumagai I, Wada H
    • Journal Title

      J.Biomech.Sci.Eng. 3

      Pages: 221-234

    • NAID

      130000079464

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390439
  • [Journal Article] Thermodynamic consequences of mutations in Vernier zone residues of a humanized anti-human epidermal growth factor receptor (EGFR) murine antibody, 5282008

    • Author(s)
      Makabe K., Nakanishi T., Tsumoto K., Tanaka Y., Kondo H., Umetsu M., Sone Y., Asano R., Kumagai I.
    • Journal Title

      J. Biol. Chem. 283

      Pages: 1156-1166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Functional expression of prestin, the outer hair cell motor protein, using the baculovirus/insect cell system2008

    • Author(s)
      Tadenuma T, Iida K, Murakoshi M, Kumano S, Tsumoto K, Ikeda K, Kobayashi T, Kumagai I, Wada H
    • Journal Title

      J.Biomech.Sci.Eng. 3

      Pages: 287-298

    • NAID

      130000079459

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390439
  • [Journal Article] リンパ球とがん細胞を認識するヒト型二重特異性抗体2008

    • Author(s)
      熊谷泉
    • Journal Title

      Drug Delivery System 23

      Pages: 518-525

    • NAID

      10024309899

    • Data Source
      KAKENHI-PROJECT-20015004
  • [Journal Article] Nanoparticles withfor biopolymer - Bioassisted room-temperature selective multistacking of inorganic particles on biopolymer film -2008

    • Author(s)
      Umetsu M., Hattori T., Kikuchi S., Muto I., Nakanishi T., Watanabe H., Kumagai I.
    • Journal Title

      J. Mater. Res. 23

      Pages: 3241-3246

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Preferential heterodimerization of a bispecific diabody based on a humanized anti-EGFR antibody 5282008

    • Author(s)
      Asano R. Sone Y., Ikoma K. Hayashi H., Nakanishi T., Umetsu M., Katayose Y., Unno M., Kudo T., Kumagai I.
    • Journal Title

      Protein Eng. Des. Sel. 10

      Pages: 597-603

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] リンパ球とがん細胞を認識するヒト型化二重特異性抗体2008

    • Author(s)
      熊谷泉, 浅野竜太郎
    • Journal Title

      Drug Delivery System 23

      Pages: 518-525

    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] 抗体ライブラリー技術の現状と今後の展望2007

    • Author(s)
      中西猛, 熊谷泉
    • Journal Title

      細胞工学 26

      Pages: 254-257

    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Highly effective recombinant format of a humanized IgG-like bispecific antibody for cancer immunotherapy with retargeting of lymphocytes to tumor cells2007

    • Author(s)
      Asano R., Watanabe Y., Kawaguchi H., Fukazawa H., Nakanishi T., Umetsu M., Hayashi H., Katayose Y., Unno M., Kudo T., Kumagai I.
    • Journal Title

      J. Biol. Chem. 282

      Pages: 27659-27665

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Structural consequences of mutaof a protein antigen-antibody complex. The case of HyHEL-10-HEL2007

    • Author(s)
      Shiroishi M., Tsumoto K., Tanaka Y., Yokota A., Nakanishi T., Kondo H., Kumagai I.
    • Journal Title

      J. Biol. Chem. 282

      Pages: 6783-6791

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] A Human antibody fragment with high affinity for biodegradable polymer film2007

    • Author(s)
      Watanabe H., Tsumoto K., Taguchi S., Yamashita K., Doi Y., Nishimiya Y., Kondo H., Umetsu M., Kumagai I.
    • Journal Title

      Bioconjug. Chem. 18

      Pages: 645-651

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Efficient leIg-like receptor signaling and crystal structure of disulfide-linked HLA-G dimer2006

    • Author(s)
      Shiroishi M., Kuroki K., Ose T., Rasubala L., Shiratori I., Arase H., Tsumoto K., Kumagai I., Kohda D., Maenaka K.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 10439-10447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] 抗 EGF レセプター・抗 CD3二重特異性抗体の抗腫瘍作用2006

    • Author(s)
      熊谷泉, 林洋毅, 浅野竜太郎
    • Journal Title

      臨床免疫 45

      Pages: 497-502

    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Structural basis for reon of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d)2006

    • Author(s)
      Shiroishi M., Kuroki K., Rasubala L., Tsumoto K., Kumagai I., Kurimoto E., Kato K., Kohda D., Maenaka K.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 103

      Pages: 16412-16417

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Humanization of the bispecific epidermal growth or receptor x CD3 diabody and its efficacy as a potential clinical reagent,2006

    • Author(s)
      Asano R., Sone Y., Makabe K., Tsumoto K., Hayashi H., Katayose Y., Unno M., Kudo T., Kumagai I.
    • Journal Title

      Clin. Cancer Res. 12

      Pages: 4036-4042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] 抗EGFレセプター・抗CD3二重特異性抗体の抗腫瘍作用2006

    • Author(s)
      熊谷 泉, ら
    • Journal Title

      臨床免疫 45

      Pages: 497-502

    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Tumor-directed lymphocyte-activating cytokines : refolding-based preparation of recombinant human interleukin-12 and an antibody variable domain-fused protein by additive-intoduced stepwise dialysis2005

    • Author(s)
      Makabe K., Asano R., Ito T., Tsumoto K., Kudo T., Kumagai I.
    • Journal Title

      Biochem. Biophys. Res. Commun. 328

      Pages: 98-105

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Bioassisted room-temperature immobilization and mineralization of zinc oxide -The structural ordering of ZnO nanoparticles into a flower-type morphorogy2005

    • Author(s)
      Umetsu M., Mizuta M., Tsumoto K., Ohara S., Takami S., Watanabe H., Kumagai I., Adschiri T.
    • Journal Title

      Adv. Mater. 17

      Pages: 2571-2575

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Nondenaturing solubilization of beta2 microglobulin from inclusion bodies by L-arginine2005

    • Author(s)
      Umetsu M., Tsumoto K., Nitta S., Adschiri T., Ejima D., Arakawa T., Kumagai I.
    • Journal Title

      Biochem. Biophys. Res. Commun. 328

      Pages: 189-197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] 巻頭言「産総研バイオ研究への期待」2005

    • Author(s)
      熊谷 泉
    • Journal Title

      AIST Today 5

      Pages: 3-3

    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Glorioso J.C., Herpes simplex virus targeting to the EGF receptor by a gD-specific soluble bridging molecule2005

    • Author(s)
      Nakano K., Asano R., Tsumoto K., Kwon H., Goins W.F., Kumagai I., Cohen J.B.
    • Journal Title

      Mol. Ther. 11

      Pages: 617-626

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Pathway to insoluble aggregates on the refolding of a single-chain Fv antibody: morphological changes of aggregated protein onrefolding2004

    • Author(s)
      Umetsu M., Ashish K., Tsumoto K., Kumagai I.
    • Journal Title

      Chem. Lett. (Jpn.) 33

      Pages: 1600-1601

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Phage-display selection of antibodies to the left end of CTX3C using synthetic fragments,2004

    • Author(s)
      Nagumo Y., Oguri H., Tsumoto K., Shindo Y., Hirama M., Tsumuraya T., Fujii I., Tomioka Y., Mizugaki M., Kumagai I.
    • Journal Title

      J. Immunol. Meth. 289

      Pages: 137-146

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] Fucose depletion from human IgG1 oligosaccharide enhancbinding enthalpy and association rate between IgG1 and FcγRIIIa2004

    • Author(s)
      Okazaki A., Shoji-Hosaka E., Nakamura K., Wakitani M., Uchida K., Kakita S., Tsumoto K., Kumagai I., Shitara K.
    • Journal Title

      J. Mol. Biol. 336

      Pages: 1239-1249

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Journal Article] A highly effectivbispecific diabody for cancer immunotherapy : cure of xenografted tumors by bispecific diabody and T-LAK cells2004

    • Author(s)
      Hayashi H., Asano R., Tsumoto K., Katayose Y., Suzuki M., Unno M., Kodama H., Takemura S., Yoshida H., Makabe K., Imai K., Matsuno S., Kumagai I., Kudo T.
    • Journal Title

      Cancer Immunol. Immunother. 53

      Pages: 497-509

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Patent] ヒト上皮増殖因子受容体を標的とした二重特異性抗体2014

    • Inventor(s)
      熊谷 泉, 浅野竜太郎, 梅津光央
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-03-26
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Patent] 高機能性lgG2型二重特異性抗体2014

    • Inventor(s)
      熊谷 泉, 浅野竜太郎, 梅津光央
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-03-25
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Patent] 剛直なヘリックス構造を有するオリゴペプチドが導入された二重特異性抗体2014

    • Inventor(s)
      熊谷 泉, 浅野竜太郎, 梅津光央
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-02-25
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Patent] ヒト型化抗EGFR抗体リジン置換可変領域断片及びその利用2010

    • Inventor(s)
      熊谷泉, 中西猛, 真田英明, 浅野竜太郎, 梅津光央
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Industrial Property Number
      2010-180693
    • Filing Date
      2010-08-12
    • Data Source
      KAKENHI-PROJECT-22226013
  • [Patent] ヒト型化抗EGFR抗体可変領域の高機能性変異体2009

    • Inventor(s)
      熊谷泉, 中西猛, 浅野竜太郎, 梅津光央
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Industrial Property Number
      2009-263147
    • Filing Date
      2009-12-18
    • Data Source
      KAKENHI-PROJECT-20015004
  • [Patent] 多量体化低分子抗体2008

    • Inventor(s)
      熊谷泉, 浅野竜太郎, 梅津光央
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Industrial Property Number
      2008-292894
    • Filing Date
      2008-11-17
    • Data Source
      KAKENHI-PROJECT-20015004
  • [Patent] 多量体化低分子抗体2008

    • Inventor(s)
      熊谷泉, 浅野竜太郎, 梅津光央
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Industrial Property Number
      2008-292894
    • Filing Date
      2008-11-17
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Patent] T細胞受容体を模倣する抗体断片及びその製造方法2008

    • Inventor(s)
      熊谷泉, 梅津光央, 渡邊秀樹, 上野貴将, 本園千尋
    • Industrial Property Rights Holder
      国立大学法人東北大学, 国立大学法人熊本大学
    • Industrial Property Number
      2008-135007
    • Filing Date
      2008-05-23
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Patent] 組換え型ポリペプチドの製造方法2008

    • Inventor(s)
      熊谷泉, 浅野竜太郎, 中西猛, 梅津光央
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Industrial Property Number
      2008-126612
    • Filing Date
      2008-05-14
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Patent] 酸化亜鉛結合性タンパク質及びその用途2008

    • Inventor(s)
      梅津光央, 熊谷泉, 浅野竜太郎, 中西猛
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Filing Date
      2008-02-14
    • Overseas
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Patent] 高機能性二重特異性抗体2006

    • Inventor(s)
      熊谷泉, 浅野竜太郎
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Filing Date
      2006-10-16
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Patent] 高機能性二重特異性抗体2006

    • Inventor(s)
      熊谷 泉, 浅野竜太郎
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Filing Date
      2006-10-16
    • Overseas
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Patent] 新規なダイアボディ型二重特異性抗体2006

    • Inventor(s)
      熊谷泉, 工藤俊雄, 津本浩平, 浅野竜太郎
    • Industrial Property Rights Holder
      東北テクノアーチ
    • Filing Date
      2006-05-19
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Patent] 金結合性タンパク質及びその用途2005

    • Inventor(s)
      塩塚秀則, 今村剛士, 熊谷泉
    • Industrial Property Rights Holder
      キャノン株式会社
    • Industrial Property Number
      2005-105155
    • Filing Date
      2005-03-31
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Patent] 金結合性タンパク質及びその用途2005

    • Inventor(s)
      塩塚 秀則, 今村 剛士, 熊谷 泉
    • Industrial Property Rights Holder
      キヤノン株式会社
    • Filing Date
      2005-03-31
    • Acquisition Date
      2005-11-10
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Patent] 構造体及び該構造体からの物質の放出方法2005

    • Inventor(s)
      塩塚 秀則, 今村 剛士, 熊谷 泉
    • Industrial Property Rights Holder
      キヤノン株式会社
    • Filing Date
      2005-03-31
    • Acquisition Date
      2005-11-10
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Presentation] 配向性の異なる二重特異性抗体の原子間力顕微鏡を用いた細胞間架橋能評価2021

    • Author(s)
      前島 敦, 石橋健太, 金賢徹, 熊谷 泉, 浅野竜太郎
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19H03511
  • [Presentation] インターロイキン2 (IL-2) の融合による二重特異性がん治療抗体の高機能化2021

    • Author(s)
      廣野琳子, 浅野竜太郎, 熊谷泉, 池袋一典
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19H03511
  • [Presentation] Development of novel quantitative method to evaluate cross-linking ability of bispecific antibodies using atomic force microscopy.2020

    • Author(s)
      Atsushi Maejima, Kenta Ishibashi, Hyonchol Kim, Kazunori Ikebukuro, Izumi Kumagai, Ryutaro Asano,
    • Organizer
      第20回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-19H03511
  • [Presentation] Development Of Novel Preparation Method For Bispecific Antibody Using Dimerizing Motif And Refolding Procedure2020

    • Author(s)
      Linko Hirono, Kazunori Ikebukuro, Izumi Kumagai, Ryutaro Asano
    • Organizer
      第20回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-19H03511
  • [Presentation] 原子間力顕微鏡を用いたがん細胞傷害活性の異なる二重特異性抗体の細胞間架橋能評価2020

    • Author(s)
      前島 敦, 石橋健太, 池袋一典, 金 賢徹, 熊谷 泉, 浅野竜太郎
    • Organizer
      日本化学会第101回春季年会
    • Data Source
      KAKENHI-PROJECT-19H03511
  • [Presentation] Characterization of circularly connected VHH bispecific antibody, Cyclobody2019

    • Author(s)
      逸見早紀、浅野竜太郎、木村昂稀、梅津光央、中西猛、熊谷泉、真壁幸樹
    • Organizer
      2019年化学系学協会東北大会
    • Data Source
      KAKENHI-PROJECT-19H03511
  • [Presentation] 材料表面特異的抗体から発想するプラズモニック膜と多孔質膜のボトムアップ作製プロセス2017

    • Author(s)
      二井手 哲平, 真鍋 法義, 中澤 光, 服部 峰充, 熊谷 泉, 梅津 光央
    • Organizer
      化学工学会第82回年会
    • Place of Presentation
      芝浦工業大学(東京)
    • Year and Date
      2017-03-06
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 抗体の足場構造への変異導入が特異的に与える影響2016

    • Author(s)
      中山 純一, 服部 峰光, 中澤 光, 金子 美華, 加藤 幸成, 熊谷 泉, 梅津 光央
    • Organizer
      第68回日本生物工学会大会
    • Place of Presentation
      富山国際会議場(富山)
    • Year and Date
      2016-09-29
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 二重特異性材料認識抗体を利用したナノ材料ペアリング2016

    • Author(s)
      二井手 哲平, 真鍋 法義, 中澤 光, 熊谷 泉, 梅津 光央
    • Organizer
      第10回バイオ関連化学シンポジウム
    • Place of Presentation
      金沢駅東もてなしドーム地下イベント広場(金沢市)
    • Year and Date
      2016-09-07
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Recombinant small antibody design for plasmonic biosensor using camel antibody with affinity for target inorganic material2016

    • Author(s)
      Takuma Sujino, Hikaru Nakazawa, Keiko Tawa, Ryutaro Asano, Izumi Kumagai and Mitsuo Umetsu
    • Organizer
      Biosensors 2016, 26th Anniversary World Congress on Biosensors
    • Place of Presentation
      Gothenburg (Sweden)
    • Year and Date
      2016-05-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Rare residues mutation approach for changing specificity of antibody2016

    • Author(s)
      Junichi Nakayama, Takamitsu Hattori, Hikaru Nakazawa, Mika K. Kaneko, Yukinari Kato, Izumi Kumagai, Mitsuo Umetsu
    • Organizer
      2016 AIChE Annual Meeting
    • Place of Presentation
      San Francisco (USA)
    • Year and Date
      2016-11-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 精製プロセスを伴わない低分子抗体の定量的薬効・蛋白質間相互作用スクリーニング2016

    • Author(s)
      杉山 在生人, 梅津 光央, 中澤 光, 浅野 竜太郎, 二井手 哲平, 服部 峰充, 熊谷 泉
    • Organizer
      第68回日本生物工学会大会
    • Place of Presentation
      富山国際会議場(富山)
    • Year and Date
      2016-09-30
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] ファージ提示法を利用した有機結晶認識ペプチドの取得とその機能評価2016

    • Author(s)
      二井手哲平, 小澤恭平, 中澤光, 笠井均, 熊谷泉, 梅津光央
    • Organizer
      第4回バイオ関連化学シンポジウム若手フォーラム
    • Place of Presentation
      金沢駅東もてなしドーム地下イベント広場(金沢市)
    • Year and Date
      2016-09-06
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Bottom-up Formation of Nanoporous Membrane from Nanoparticles via Anti-inorganic Antibody2016

    • Author(s)
      Teppei Niide, Noriyoshi Manabe, Hikaru Nakazawa, Izumi Kumagai, and Mitsuo Umetsu
    • Organizer
      Young Asian Biological Engineers' Community 2016
    • Place of Presentation
      シーガイアコンベンションセンター(宮崎市)
    • Year and Date
      2016-10-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] ラクダ可変領域を利用した自発的多重多価化抗体の提案2016

    • Author(s)
      藤井 滉人, 田中 良和, 浅野 竜太郎, 熊谷 泉, 梅津 光央
    • Organizer
      化学工学会第48回秋季大会
    • Place of Presentation
      徳島大学(徳島市)
    • Year and Date
      2016-09-06
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Silkworm Expression System Suitable for High-Throughput Screening of Antibody Fragment2016

    • Author(s)
      Mami Shibata, Hikaru Nakazawa, Masahiko Kato, Hidekazu Nagaya, Hideaki Sanada, Izumi Kumagai, Mitsuo Umetsu
    • Organizer
      2016 AIChE Annual Meeting
    • Place of Presentation
      San Francisco (USA)
    • Year and Date
      2016-11-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Domain library approach for designing therapeutic small antibody with high cytotoxicity for tumor cells2016

    • Author(s)
      Aruto Sugiyama, Mitsuo Umetsu, Katsuhiro Hosokawa, Ryutaro Asano, and Izumi Kumagai
    • Organizer
      2016 AIChE Annual Meeting
    • Place of Presentation
      San Francisco (USA)
    • Year and Date
      2016-11-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Selection of CDR-Mimic Peptide By Using Phage Display Method2016

    • Author(s)
      Miki Yanagisawa, Teppei Niide, Takamitsu Hattori, Hikaru Nakazawa, Izumi Kumagai and Mitsuo Umetsu
    • Organizer
      2016 AIChE Annual Meeting
    • Place of Presentation
      San Francisco (USA)
    • Year and Date
      2016-11-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Peptide with affinity for organic crystals : peptide selection, affinity analysis, and formation of protein-organic crystals2016

    • Author(s)
      Teppei Niide, Kyohei Ozawa, Hikaru Nakazawa, Izumi Kumagai, Mitsuo Umetsu
    • Organizer
      17th European congress on biotechnology
    • Place of Presentation
      Krakow(Poland)
    • Year and Date
      2016-07-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] ELISA法との組合せによる未精製抗体の定量的薬効・蛋白質間相互作用スクリーニング2016

    • Author(s)
      杉山 在生人, 梅津 光央, 中澤 光, 浅野 竜太郎, 二井手 哲平, 服部 峰充, 熊谷 泉
    • Organizer
      第16回日本蛋白質科学会年会
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Year and Date
      2016-06-08
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] ファージ提示法を利用したCDR模倣ペプチドライブラリーの構築2016

    • Author(s)
      柳沢 美貴, 二井手 哲平, 服部 峰充, 中澤 光, 熊谷 泉, 梅津 光央
    • Organizer
      第68回日本生物工学会大会
    • Place of Presentation
      富山国際会議場(富山)
    • Year and Date
      2016-09-29
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Quantitative screening for highly cytotoxic bispecific antibody without purification process2016

    • Author(s)
      Aruto Sugiyama, Hikaru Nakazawa, Ryutaro Asano, Teppei Niide, Izumi Kumagai and Mitsuo Umetsu
    • Organizer
      Protein Therapeutics Summit
    • Place of Presentation
      San Francisco (USA)
    • Year and Date
      2016-06-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 抗体の足場構造への変異導入による新規の分子認識能改変手法の開発2016

    • Author(s)
      中山 純一, 服部 峰光, 中澤 光, 金子 美華, 加藤 幸成, 熊谷 泉, 梅津 光央
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] アミノ酸配列の相同性から考察するDiabody型二重特異性抗体の構造均一性2015

    • Author(s)
      小野寺朋子、梅津光央、杉山在生人、田中良和、中澤光、服部峰充、浅野竜太郎、熊谷泉
    • Organizer
      第67回日本生物工学会大会
    • Place of Presentation
      城山観光ホテル(鹿児島市)
    • Year and Date
      2015-10-26
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 蛋白質の分子認識を利用したプラズモニック膜と多孔質膜のボトムアップ作製プロセス2015

    • Author(s)
      二井手 哲平, 真鍋 法義, 中澤 光, 服部 峰充, 熊谷 泉, 梅津 光央
    • Organizer
      化学工学会群馬大会
    • Place of Presentation
      市民文化会館(桐生市)
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] がん細胞成長阻害活性を有する四量体化抗EGFR一本鎖抗体の調製と機能評価2015

    • Author(s)
      浅野 竜太郎, 小山 典明, 鉞陽 介, 古本 祥三, 荒井 杏子, 尾形 裕未, 梅津 光央, 熊谷 泉
    • Organizer
      第15回日本蛋白質科学会年会
    • Place of Presentation
      あわぎんホール(徳島市)
    • Year and Date
      2015-06-24
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] ドメインライブラリー的発想によるがん治療二重特異性抗体の高活性ルール抽出2015

    • Author(s)
      杉山在生人, 中澤光, 浅野竜太郎, 熊谷泉, 梅津光央
    • Organizer
      化学工学会第79年会
    • Place of Presentation
      芝浦工業大学(東京都)
    • Year and Date
      2015-03-21
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] がん治療低分子抗体の迅速スクリーニングを利用した高活性ルールの抽出2015

    • Author(s)
      杉山 在生人, 梅津 光央, 中澤 光, 浅野 竜太郎, 熊谷 泉
    • Organizer
      第67回日本生物工学会大会
    • Place of Presentation
      城山観光ホテル(鹿児島市)
    • Year and Date
      2015-10-26
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Protein design for interface molecule between nanomaterials : Buildup from nanoparticles to porous metal materials2015

    • Author(s)
      Mitsuo Umetsu, Noriyoshi Manabe, Hikaru Nakazawa, Izumi Kumagai
    • Organizer
      2nd International Conference on Bioinspired and Biobased Chemistry & Materials
    • Place of Presentation
      Nice (France)
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 最適な二重特異性低分子抗体を構成する抗体断片の迅速スクリーニング2015

    • Author(s)
      杉山 在生人、梅津 光央、中澤 光、細川 勝洸、浅野 竜太郎、熊谷 泉
    • Organizer
      第15回日本蛋白質科学会年会
    • Place of Presentation
      あわぎんホール(徳島市)
    • Year and Date
      2015-06-25
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Highly Cytotoxic Therapeutic Antibody Identified from High Throughput Screening2015

    • Author(s)
      Aruto Sugiyama, Hikaru Nakazawa, Ryutaro Asano, Izumi Kumagai, Mitsuo Umetsu
    • Organizer
      2015 International Symposium on Chemical and Polyscale Technologies for Biomedical Application and Environmental Sustainability
    • Place of Presentation
      Taipei (Taiwan)
    • Year and Date
      2015-09-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] High throughput screening of cancer therapeutic small antibody designed from domain library2015

    • Author(s)
      Aruto Sugiyama, Mitsuo Umetsu, Hikaru Nakazawa, Hosokawa, Katsuhiro, Ryutaro Asano, Izumi Kumagai
    • Organizer
      Pacifichem2015
    • Place of Presentation
      Honolulu (USA)
    • Year and Date
      2015-12-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] ドメインライブラリー的発想によるがん治療スマート抗体の迅速設計スクリーニング2015

    • Author(s)
      杉山在生人, 中澤光, 浅野竜太郎, 熊谷泉, 梅津光央
    • Organizer
      日本化学会第95春季年会
    • Place of Presentation
      日本大学(舟橋市)
    • Year and Date
      2015-03-26
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] シングルドメインを利用した二重二価がん治療抗体BibiAnの会合特性と機能評価2015

    • Author(s)
      藤井 滉人、田中 良和、中澤 光、浅野 竜太郎、熊谷 泉、梅津 光央
    • Organizer
      第15回日本蛋白質科学会年会
    • Place of Presentation
      あわぎんホール(徳島市)
    • Year and Date
      2015-06-25
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] ドメインライブラリーを利用した低分子抗体の迅速スクリーニングから見える活性ルール2015

    • Author(s)
      杉山 在生人, 梅津 光央, 中澤 光, 浅野 竜太郎, 熊谷 泉
    • Organizer
      第38回分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド(神戸市)
    • Year and Date
      2015-12-03
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Structural control and visualization of a smart bispecific and bivalent antibody2015

    • Author(s)
      Hiroto Fujii, Yoshikazu Tanaka, Hikaru Nakazawa, Ryutaro Asano, Izumi Kumagai, Mitsuo Umetsu
    • Organizer
      Pacifichem2015
    • Place of Presentation
      Honolulu (USA)
    • Year and Date
      2015-12-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Diabody型二重特異性抗体の構築におけるアミノ酸配列相同性の影響2015

    • Author(s)
      菅野 朋子, 梅津 光央, 杉山 在生人, 田中 良和, 中澤 光, 服部 峰充, 浅野 竜太郎, 熊谷 泉
    • Organizer
      第38回分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド(神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Recombinant small antibody design for plasmonic biosensor using camel antibody with affinity for target inorganic material2015

    • Author(s)
      Takuma Sujino, Hikaru Nakazawa, Keiko Tawa, Ryutaro Asano, Izumi Kumagai, Mitsuo Umetsu
    • Organizer
      Pacifichem2015
    • Place of Presentation
      Honolulu (USA)
    • Year and Date
      2015-12-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Nanoporous gold membrane from ZnO-Au nanoparticle assembly induced by material-binding bispecific antibodies2015

    • Author(s)
      Mitsuo Umetsu, Teppei Niide, Noriyoshi Manabe, Hikaru Nakazawa, Izumi Kumagai
    • Organizer
      Hybrid Materials 2015
    • Place of Presentation
      Sites (Spain)
    • Year and Date
      2015-03-12
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Organic crystal-binding peptide : crystal growth control and immobilization of functional protein on organic crystals2015

    • Author(s)
      Teppei Niide, Kyohei Ozawa, Hikaru Nakazawa, Daniel Oliveira, Hitoshi Kasai, Mari Onodera, Ryutaro Asano, Izumi Kumagai, Mitsuo Umetsu
    • Organizer
      The 22nd Symposium of Young Asian Biochemical Engineers' Community 2015
    • Place of Presentation
      Chuncheon (Korea)
    • Year and Date
      2015-10-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Bio-fabrication of Nanoporous Gold Membrane with Anti-inorganic Bispecific Nanobody2015

    • Author(s)
      Teppei Niide, Manabe Noriyoshi, Hikaru Nakazawa, Izumi Kumagai, Mitsuo Umetsu
    • Organizer
      Pacifichem2015
    • Place of Presentation
      Honolulu (USA)
    • Year and Date
      2015-12-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Design of smart antibody with bispecific and bivalent function by fusing single camel antigen-binding fragment onto dimerized single-chain Fv2014

    • Author(s)
      Hiroto Fujii, Takuma Sujino, Hikaru Nakazawa, Noriyoshi Manabe, Ryutaro Asano, Izumi Kumagai, Mitsuo Umetsu
    • Organizer
      248th ACS National Meeting & Exposition Submission Confirmation
    • Place of Presentation
      San Francisco (USA)
    • Year and Date
      2014-08-12
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Find out the most effective bispecific antibody for cancer therapy by High throughput screening methodology2014

    • Author(s)
      Aruto Sugiyama, Mitsuo Umetsu, Hikaru Nakazawa, Ryutaro Asano, Izumi Kumagai
    • Organizer
      Tohoku University's chemistry Summer School 2014
    • Place of Presentation
      東北大学(仙台)
    • Year and Date
      2014-08-25
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 二重特異性抗体のタンパク質工学を駆使した高機能化2014

    • Author(s)
      浅野 竜太郎, 熊谷 泉
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学(熊本)
    • Year and Date
      2014-03-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 低分子二重特異性がん治療抗体のドメイン組換えによるin vivo抗腫瘍効果の増強2014

    • Author(s)
      浅野 竜太郎, 熊谷 崇, 瀧 慎太郎, 尾形 裕未, 岡田 麻衣, 荒井 杏子, 梅津 光央, 熊谷 泉
    • Organizer
      平成25年度「個体レベルでのがん研究支援活動」ワークショップ
    • Place of Presentation
      琵琶湖ホテル(滋賀県大津市)
    • Year and Date
      2014-02-18
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] がん治療スマート抗体の迅速設計を指向したスクリーニング法開発と活性ルール抽出2014

    • Author(s)
      杉山在生人, 梅津光央, 中澤光, 浅野竜太郎, 熊谷泉
    • Organizer
      第37回分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-11-25
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 二重特異性抗体の配向性の違いがおよぼすFc融合体の機能への影響2014

    • Author(s)
      浅野竜太郎, 今野翔太, 下村一平, 梅津光央, 熊谷泉
    • Organizer
      GE Life Sciences Day 2014
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-08-01
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] High throughput screening of the effective bispecific antibodies for cancer2014

    • Author(s)
      Aruto Sugiyama, Mitsuo Umetsu, Hikaru Nakazawa, Ryutaro Asano, Izumi Kumagai
    • Organizer
      248th ACS National Meeting & Exposition Submission Confirmation
    • Place of Presentation
      San Francisco (USA)
    • Year and Date
      2014-08-12
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Porous membrane design from nanoparticles by using the material-binding bispecific antibodies2014

    • Author(s)
      Mitsuo Umetsu, Noriyoshi Manabe, Hikaru Nakazawa, Izumi Kumagai
    • Organizer
      2014 E-MRS
    • Place of Presentation
      Lille (France)
    • Year and Date
      2014-05-26
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] スマート二重二価抗体 : 抗体可変領域からの新規デザイン2014

    • Author(s)
      藤井滉入, 筋野拓馬, 中澤光, 真鍋法義, 浅野竜太郎, 熊谷泉, 梅津光央
    • Organizer
      第8回バイオ関連シンポジウム
    • Place of Presentation
      岡山大学(岡山)
    • Year and Date
      2014-09-11
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 一本鎖抗体の自己会合特性を活かした多価・多重特異性抗体設計2014

    • Author(s)
      梅津 光央, 藤井 滉人, 筋野 拓馬, 真鍋 法義, 中澤 光, 田中 良和, 浅野 竜太郎, 熊谷 泉
    • Organizer
      化学工学会第79年会
    • Place of Presentation
      岐阜大学(岐阜市)
    • Year and Date
      2014-03-20
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 低分子二重特異性がん治療抗体の機能的な構造形態に関する実験的考察2014

    • Author(s)
      浅野竜太郎, 永井圭佑, 瀧慎太郎, 梅津光央, 熊谷泉
    • Organizer
      第41回生体分子化学討論会
    • Place of Presentation
      九州大学西新プラザ(福岡市)
    • Year and Date
      2014-06-06
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 抗体断片群からの迅速な二重特異性低分子抗体の調製と活性ルール抽出2014

    • Author(s)
      杉山在生人, 中澤光, 細川勝洸, 浅野竜太郎, 熊谷泉, 梅津光央
    • Organizer
      第66回日本生物工学会大会
    • Place of Presentation
      札幌コンベンションセンター(札幌)
    • Year and Date
      2014-09-11
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 水和ZmOナノクラスタへのヒスチジン吸着の第一原理分子動力学計算2014

    • Author(s)
      加藤幸一郎, 福澤薫, 熊谷泉, 梅津光央
    • Organizer
      第61回応用物理学会春季学術講演会
    • Place of Presentation
      青山学院大学(神奈川県相模原市)
    • Year and Date
      2014-03-18
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Fc融合二重特異性抗体のドメイン組換えによるin vivo抗腫瘍効果の増強2014

    • Author(s)
      浅野竜太郎, 今野翔太, 下村一平, 尾形裕未, 岡田麻衣, 荒井杏子, 梅津光央, 熊谷泉
    • Organizer
      平成26年度「個体レベルでのがん研究支援活動」ワークショップ
    • Place of Presentation
      琵琶湖ホテル(大津市)
    • Year and Date
      2014-02-06
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 低分子二重特異性二価抗体(BibiAn)のin vivo抗腫瘍効果2014

    • Author(s)
      藤井滉人, 筋野拓馬, 中澤光, 真鍋法義, 浅野竜太郎, 熊谷泉, 梅津光央
    • Organizer
      平成26年度「個体レベルでのがん研究支援活動」ワークショップ
    • Place of Presentation
      琵琶湖ホテル(大津市)
    • Year and Date
      2014-02-06
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] がん治療スマート抗体の迅速設計を目指したスクリーニング法の開発2014

    • Author(s)
      杉山在生人, 中澤光, 細川勝洸, 浅野竜太郎, 熊谷泉, 梅津光央
    • Organizer
      平成26年度がん若手研究者ワークショップ
    • Place of Presentation
      蓼科グランドホテル(長野)
    • Year and Date
      2014-09-05
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 高親和性化低分子二重特異性がん治療抗体のin vivo抗腫瘍効果2014

    • Author(s)
      細川 勝洸, 浅野 竜太郎, 瀧 慎太郎, 梅津 光央, 熊谷 泉
    • Organizer
      平成25年度「個体レベルでのがん研究支援活動」ワークショップ
    • Place of Presentation
      琵琶湖ホテル(滋賀県大津市)
    • Year and Date
      2014-02-18
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 一本鎖抗体の自発的二量体化から発想するラクダ可変領域シングルドメインを利用した多重特異性多価抗体2014

    • Author(s)
      藤井 滉人, 筋野 拓馬, 中澤 光, 真鍋 法義, 浅野 竜太郎, 熊谷 泉, 梅津 光央
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学(名古屋市)
    • Year and Date
      2014-03-27
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] バイオインターフェイス分子を使ったナノ粒子アセンブリからの金属多孔質膜作製2014

    • Author(s)
      真鍋法義, 二井出哲平, 中澤光, 熊谷泉, 梅津光央
    • Organizer
      「プロセスインテグレーションによる次世代ナノシステムの創製」3研究領域合同第3回公開シンポジウム
    • Place of Presentation
      コクヨホール(東京)
    • Year and Date
      2014-10-01
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 抗体可変領域断片の会合特性から発想する天然型よりスマートかつ高機能な抗体設計2014

    • Author(s)
      藤井滉人, 筋野拓馬, 中澤光, 真鍋法義, 浅野竜太郎, 熊谷泉, 梅津光央
    • Organizer
      生体機能関連化学部会若手の会 第26回サマースクール
    • Place of Presentation
      ラフォーレ蔵王(刈田郡蔵王町)
    • Year and Date
      2014-07-25
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Cytotoxic enhancement of a bispecific diabody with specificity for EGFR and CD3 by rearranging a domain order2014

    • Author(s)
      Ryutaro Asano, Takashi Kumagai, Keisuke Nagai, Shintaro Taki, Mitsuo Umetsu, Izumi Kumagai
    • Organizer
      FEBS-EMBO 2014
    • Place of Presentation
      Paris (France)
    • Year and Date
      2014-09-01
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 最適な二重特異性低分子抗体を構成する抗体断片の迅速スクリーニング2014

    • Author(s)
      杉山在生人、梅津光央、中澤光、浅野竜太郎、熊谷泉
    • Organizer
      第14回日本蛋白質科学会年会
    • Place of Presentation
      横浜産貿ホールマリネリア(横浜市)
    • Year and Date
      2014-06-25
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] ヒト上皮増殖因子受容体を標的とした多価抗体の開発2014

    • Author(s)
      浅野竜太郎, 小山典明, 古本祥三, 荒井杏子, 尾形裕未, 梅津光央, 熊谷泉
    • Organizer
      化学療法基盤支援活動第3回シンポジウム
    • Place of Presentation
      万国津梁館(名護市)
    • Year and Date
      2014-05-12
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] scFv二価設計にラクダ由来VHHシングルドメイン構造をかけ合わせたスマート二重二価抗体 : BibiAn2014

    • Author(s)
      藤井滉人, 筋野拓馬, 中澤光, 真鍋法義, 浅野竜太郎, 熊谷泉, 梅津光央
    • Organizer
      第37回分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-11-25
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 低分子二重特異性抗体の配向性の違いがもたらすFc融合体の機能への影響2014

    • Author(s)
      浅野竜太郎, 今野翔太, 下村一平, 梅津光央, 熊谷泉
    • Organizer
      第14回日本蛋白質科学会年会
    • Place of Presentation
      横浜産貿ホールマリネリア(横浜市)
    • Year and Date
      2014-06-25
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] がん細胞成長阻害活性を有する多量体化抗EGFR一本鎖抗体の精密機能解析2014

    • Author(s)
      浅野竜太郎, 小山典明, 鉞陽介, 古本祥三, 荒井杏子, 尾形裕未, 梅津光央, 熊谷泉
    • Organizer
      第66回日本生物工学会大会
    • Place of Presentation
      札幌コンベンションセンター(札幌)
    • Year and Date
      2014-09-11
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Nanobiotechnology for building up porous metal membrane from nanoparticles2014

    • Author(s)
      Mitsuo Umetsu, Noriyoshi Manabe, Hikaru Nakazawa, Izumi Kumagai
    • Organizer
      4th International Solvothermal and Hydrothermal Association Conference
    • Place of Presentation
      Bordeaux(France)
    • Year and Date
      2014-10-28
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 低分子二重特異性がん治療抗体の網羅的な作製と機能評価2014

    • Author(s)
      杉山 在生人, 浅野 竜太郎, 中澤 光, 梅津 光央, 熊谷 泉
    • Organizer
      平成25年度「個体レベルでのがん研究支援活動」ワークショップ
    • Place of Presentation
      琵琶湖ホテル(滋賀県大津市)
    • Year and Date
      2014-02-18
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 一本鎖抗体の自発的二量体化から発想するラクダ可変領域シングルドメインを利用した多重多価抗体2014

    • Author(s)
      藤井滉入, 筋野拓馬, 中澤光, 真鍋法義, 浅野竜太郎, 熊谷泉, 梅津光央
    • Organizer
      第14回日本蛋白質科学会年会
    • Place of Presentation
      横浜産貿ホールマリネリア(横浜市)
    • Year and Date
      2014-06-25
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 異なる抗体クローン用いて作製した低分子二重特異性抗体の比較検討2014

    • Author(s)
      浅野竜太郎, 永井圭佑, 梅津光央, 熊谷泉
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Year and Date
      2014-10-18
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Effective Engineered Antibody Formats2014

    • Author(s)
      Izumi Kumagai
    • Organizer
      CMC Strategy Forum Japan 2014
    • Place of Presentation
      ホテルオークラ東京(東京)
    • Year and Date
      2014-12-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Cytotoxic enhancement of a small bispecific antibody with specificity for EGFR and CD3 by rearranging a domain order2013

    • Author(s)
      Ryutaro Asano, Takahashi Kumagai, Keisuke Nagai, Shintaro Taki, Mitsuo Umetsu, Izumi Kumagai
    • Organizer
      International Conference on Structural Genomics 2013
    • Place of Presentation
      京王プラザホテル札幌(札幌)
    • Year and Date
      2013-07-31
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Novel design with multimeric proteins for multivalent antibodies expressed in E. coli2013

    • Author(s)
      Rui Todokoro, Hikaru Nakazawa, Ryutaro Asano, Izumi Kumagai, Mitsuo Umetsu
    • Organizer
      International Conference on Structural Genomics 2013
    • Place of Presentation
      京王プラザホテル札幌(札幌)
    • Year and Date
      2013-07-30
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Design of interface molecules for biosensor using camel antibody with affinity for target inorganic material2013

    • Author(s)
      Takuma Sujino, Hikaru Nakazawa, Ryutaro Asano, Izumi Kumagai, Mitsuo Umetsu
    • Organizer
      International Conference on Structural Genomics 2013
    • Place of Presentation
      京王プラザホテル札幌(札幌)
    • Year and Date
      2013-07-30
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Construction of small bispecific antibody mutants with enhanced anti-tumor activity2013

    • Author(s)
      Katsuhiro Hosokawa, Ryutaro Asano, Shintaro Taki, Mitsuo Umetsu, and Izumi Kumagai
    • Organizer
      International Symposium of Chemical-Environmental-Biomedical Technology 2013
    • Place of Presentation
      グリーンピア岩沼(宮城県岩沼市)
    • Year and Date
      2013-09-09
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] In vivo assembly design : multivalent antibody generation2013

    • Author(s)
      Rui Todokoro, Hikaru Nakazawa, Ryutaro Asano, Izumi Kumagai, and Mitsuo Umetsu
    • Organizer
      International Symposium of Chemical-Environmental-Biomedical Technology 2013
    • Place of Presentation
      グリーンピア岩沼(宮城県岩沼市)
    • Year and Date
      2013-09-09
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Functional enhancement of a small bispecific antibody using high affinity Fv mutants isolated by phage display2013

    • Author(s)
      Katsuhiro Hosokawa, Ryutaro Asano, Shintaro Taki, Mitsuo Umetsu, Izumi Kumagai
    • Organizer
      International Conference on Structural Genomics 2013
    • Place of Presentation
      京王プラザホテル札幌(札幌)
    • Year and Date
      2013-07-31
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] EGFRとCD16を標的としたヒト型化低分子二重特異性抗体の巻き戻し法を用いた開発2013

    • Author(s)
      浅野 竜太郎, 中山 真, 梅津 光央, 熊谷 泉
    • Organizer
      第13回日本蛋白質科学会年会
    • Place of Presentation
      とりぎん文化会館(鳥取市)
    • Year and Date
      2013-06-14
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Protein engineering for site-specific bioconjugation chemistry : Construction of multiple functional low-molecular antibodies2013

    • Author(s)
      Mitsuo Umetsu, Asami Ueda, Takeshi Nakanishi, Kentaro Hashikami, Ryutaro Asano, Izumi Kumagai
    • Organizer
      Antibody Engineering & Therapeutics
    • Place of Presentation
      Huntington Beach (USA)
    • Year and Date
      2013-12-09
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Protein Engineering for assembling inorganic nanomaterials2013

    • Author(s)
      Mitsuo Umetsu, Takamitsu Hattori, Takanari Togashi, Izumi Kumagai
    • Organizer
      Third International Conference on Multifunctional, Hybrid and Nanomaterials
    • Place of Presentation
      Sorrento (Italy)
    • Year and Date
      2013-03-05
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 無機材料標的ラクダ抗体を錨としたバイオセンサー指向インターフェイス設計2013

    • Author(s)
      梅津 光央, 筋野 拓馬, 中澤光, 浅野 竜太郎, 熊谷 泉
    • Organizer
      第13回日本蛋白質科学会年会
    • Place of Presentation
      とりぎん文化会館(鳥取市)
    • Year and Date
      2013-06-12
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Self-assembly system in E. coli for generating multivalent antibody2013

    • Author(s)
      Rui Todokoro, Hikaru Nakazawa, Ryutaro Asano, Izumi Kumagai, Mitsuo Umetsu
    • Organizer
      Antibody Engineering & Therapeutics
    • Place of Presentation
      Huntington Beach (USA)
    • Year and Date
      2013-12-09
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Fc融合二重特異性がん治療抗体の配向性の検討と親和性向上による高機能化2013

    • Author(s)
      浅野 竜太郎, 今野 翔太, 下村 一平, 梅津 光央, 熊谷 泉
    • Organizer
      第65回日本生物工学会大会
    • Place of Presentation
      広島国際会議場(広島市)
    • Year and Date
      2013-09-20
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Design of bispecific interface molecules for biosensor using camel antibody with affinity for target inorganic material2013

    • Author(s)
      Takuma Sujino, Hikaru Nakazawa, Ryutaro Asano, Izumi Kumagai, Mitsuo Umetsu
    • Organizer
      International Symposium of Chemical-Environmental-Biomedical Technology 2013
    • Place of Presentation
      グリーンピア岩沼(宮城県岩沼市)
    • Year and Date
      2013-09-09
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Development of a screeing method for optimal antibody fragment pairs to construct effective small bispecific antibodies2013

    • Author(s)
      Aruto Sugiyama, Ryutaro Asano, Hikaru Nakazawa, Mitsuo Umetsu, Izumi Kumagai
    • Organizer
      International Conference on Structural Genomics 2013
    • Place of Presentation
      京王プラザホテル札幌(札幌)
    • Year and Date
      2013-07-31
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 高親和性変異の導入による低分子型二重特異性がん治療抗体の高機能化2013

    • Author(s)
      細川 勝洸, 浅野 竜太郎, 瀧慎 太郎, 梅津 光央, 熊谷 泉
    • Organizer
      がん若手研究者ワークショップ
    • Place of Presentation
      蓼科グランドホテル滝の湯(長野県茅野市)
    • Year and Date
      2013-09-05
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Small bispecific antibodies built from high affinity Fv mutants for founctional enhancement2013

    • Author(s)
      Katsuhiro Hosokawa, Ryutaro Asano, Shintaro Taki, Mitsuo Umetsu, Izumi Kumagai
    • Organizer
      Antibody Engineering & Therapeutics
    • Place of Presentation
      Huntington Beach (USA)
    • Year and Date
      2013-12-09
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Material-binding antibody as an interface tool for manipulating nano-materials2013

    • Author(s)
      Mitsuo Umetsu, Takamitsu Hattori, Takeshi Nakanishi, Izumi Kumagai
    • Organizer
      2013 Materisl Research Society Spring Meeting
    • Place of Presentation
      San Francisco (USA)
    • Year and Date
      2013-04-02
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Generation of the antibodies with high affinity for inorganic nanomaterials by peptide-grafting and molecular evolutionary methods2013

    • Author(s)
      Mitsuo Umetsu, Takamitsu Hattori, Satoshi Ohara, Takeshi Nakanishi, Izumi Kumagai
    • Organizer
      27th Annual Symposium of the Protein Society
    • Place of Presentation
      Boston (USA)
    • Year and Date
      2013-07-22
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Restructure of Sequential CDR Walking Approach in CAnIGET Method2012

    • Author(s)
      Yasuko Seta, Mitsuo Umetsu, Hikaru Nakazawa, Seiichi Takami, Izumi Kumagai
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場 (福岡市)
    • Year and Date
      2012-12-12
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Protein engineering for site-specific bioconjugation chemistry: Construction of multiple functional lowmolecular antibodies2012

    • Author(s)
      Mitsuo Umetsu, Asami Ueda, Takeshi Nakanishi, Kentaro Hashikami, Ryutaro Asano, Izumi Kumagai
    • Organizer
      第50回日本生物物理学会年会
    • Place of Presentation
      名古屋大学 (名古屋市)
    • Year and Date
      2012-09-22
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] LEGO design for multivalent antibodies expressed in E.coli2012

    • Author(s)
      Rui Todokoro, Hikaru Nakazawa, Ryutaro Asano, Mitsuo Umetsu, Izumi Kumagai
    • Organizer
      The 19th Symposium of Young Asian Biochemical Engineers' Community 2012
    • Place of Presentation
      徳島大学 (徳島市)
    • Year and Date
      2012-10-27
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Detailed Analysis on an Effective Multimeric Molecule of Small Recombinant Bispecific Antibody2012

    • Author(s)
      Ryutaro Asano, Shintaro Taki, Keiko Ikoma, Mitsuo Umetsu, Izumi Kumagai
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場 (福岡市)
    • Year and Date
      2012-12-14
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Experimental Study on Functional Domain Order of a Small Bispecific Antibody2012

    • Author(s)
      Keisuke Nagai, Ryutaro Asano, Hideaki Sanada, Mitsuo Umetsu, Izumi Kumagai
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場 (福岡市)
    • Year and Date
      2012-12-14
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Build up Design for Multivalent Antibodies on Multimeric Protein Platform2012

    • Author(s)
      Shota Konno, Ryutaro Asano, Ippei Shimomura, Mitsuo Umetsu, Izumi Kumagai
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場 (福岡市)
    • Year and Date
      2012-12-12
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] Functional enhancement of a small recombinant bispecific antibody by introduction of mutations for cancer immunotherapy2012

    • Author(s)
      Katsuhiro Hosokawa, Ryutaro Asano, Shintaro Taki, Mitsuo Umetsu, Izumi Kumagai
    • Organizer
      The 19th Symposium of Young Asian Biochemical Engineers' Community 2012
    • Place of Presentation
      徳島大学 (徳島市)
    • Year and Date
      2012-10-27
    • Data Source
      KAKENHI-PROJECT-24000011
  • [Presentation] 次世代抗体医薬開発のフロンティア2010

    • Author(s)
      熊谷泉
    • Organizer
      第313回CBI学会研究講演会
    • Place of Presentation
      東京(依頼講演)
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-22226013
  • [Presentation] ピンポイント化学接合が可能なタンパク質工学的抗体デザイン2010

    • Author(s)
      熊谷泉
    • Organizer
      BMB2010第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-22226013
  • [Presentation] フォールドに基づくタンパク質工学 -次世代抗体医薬への展開-2009

    • Author(s)
      熊谷泉
    • Organizer
      第8回医薬・バイオセミナー
    • Place of Presentation
      東京
    • Year and Date
      2009-06-30
    • Data Source
      KAKENHI-PROJECT-20015004
  • [Presentation] The design of PEGylated multivalent antibodies for convenient preparation from insoluble aggregates produced in bacteria2009

    • Author(s)
      熊谷泉
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-20015004
  • [Presentation] ピンポイントPEG化修飾操作を導入した二重特異性抗体巻き戻し技法2009

    • Author(s)
      熊谷泉
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-20015004
  • [Presentation] タンパク質フォールドの組換えと次世代抗体医薬2009

    • Author(s)
      熊谷泉
    • Organizer
      NMR構造生物学研究会第38回ワークショップ
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-06
    • Data Source
      KAKENHI-PROJECT-20015004
  • [Presentation] 低分子抗体巻き戻しプロセスへのPEG修飾操作の導入 : 効率的巻き戻し・タンパク質安定化・体内動態向上を骨指して2008

    • Author(s)
      熊谷泉
    • Organizer
      BMB2008(第31回日本分子生物学会年会ら第81回日本生化学会大会合同大会)
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Presentation] 次世代抗体創薬のバイオ工学を目指して2008

    • Author(s)
      熊谷泉
    • Organizer
      第11回シンポジウム ゲノム創薬フォーラム
    • Place of Presentation
      東京
    • Year and Date
      2008-11-07
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Presentation] 低分子抗体の巻き戻し中間体におけるPEG修飾2008

    • Author(s)
      熊谷泉
    • Organizer
      第8回日本蛋白質科学会年会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-12
    • Data Source
      KAKENHI-PROJECT-20015004
  • [Presentation] 低分子抗体の巻き戻し中間体におけるPEG修飾2008

    • Author(s)
      熊谷泉
    • Organizer
      第8回日本蛋白質科学会年会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-12
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Presentation] 低分子抗体巻き戻しプロセスへのPEG修飾操作の導入 : 効率的巻き戻し・タンパク質安定化・体内動態向上を目指して2008

    • Author(s)
      熊谷泉
    • Organizer
      BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-20015004
  • [Presentation] 次世代抗体医薬の分子設計2008

    • Author(s)
      熊谷泉
    • Organizer
      化学工学会第40回秋季大会
    • Place of Presentation
      仙台
    • Year and Date
      2008-09-25
    • Data Source
      KAKENHI-PROJECT-20015004
  • [Presentation] 次世代抗体創薬のバイオ工学を目指して2008

    • Author(s)
      熊谷泉
    • Organizer
      ゲノム創薬フォーラム第11回シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2008-11-07
    • Data Source
      KAKENHI-PROJECT-20015004
  • [Presentation] 次世代抗体創薬のバイオ工学を骨指して2008

    • Author(s)
      熊谷泉
    • Organizer
      ゲノム創薬フォーラム第11回シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2008-11-07
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Presentation] 次世代抗体医薬の分子設計2008

    • Author(s)
      熊谷泉
    • Organizer
      化学工学会第40回秋季大会
    • Place of Presentation
      仙台
    • Year and Date
      2008-09-25
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Presentation] アカデミアからの蛋白質製造の技術移管と効率的プロセス開発2007

    • Author(s)
      熊谷泉
    • Organizer
      第5回トランスレーショナルリサーチ研修会
    • Place of Presentation
      神戸
    • Year and Date
      2007-03-02
    • Data Source
      KAKENHI-PROJECT-16106011
  • [Presentation] 抗体分子からバイオインターフェイスへの展開2006

    • Author(s)
      熊谷泉
    • Organizer
      Bio Japan 2006
    • Place of Presentation
      大阪
    • Year and Date
      2006-09-15
    • Data Source
      KAKENHI-PROJECT-16106011
  • 1.  TSUMOTO Kouhei (90271866)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 18 results
  • 2.  ASANO Ryutaro (80323103)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 110 results
  • 3.  UMETSU Mitsuo (70333846)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 121 results
  • 4.  WADA Hiroshi (30111264)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 3 results
  • 5.  TANAKA YOSHIKAZU (20374225)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 10 results
  • 6.  MAKABE KOKI (20508072)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 7.  MIURA Kin-ichiro (30000227)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 8.  武藤 あきら (80034635)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  KOBAYASHI Toshimitsu (80133958)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 10.  HIRAO Ichiro (50173216)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  池村 淑道 (50025475)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  真木 寿治 (20199649)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  MITSUI Yukio (40012637)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  GO Nobuhiro (50011549)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  KIDERA Akinori (00186280)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  IKEDA Katsuhisa (70159614)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  三田 和英 (30159165)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  五條堀 孝 (50162136)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  渡辺 公綱 (00134502)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 20.  USAMI Shinichi (10184996)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  ISHIHARA Kenji (00312596)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 22.  YURA Kei (50252226)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  NISHIKAWA Ken (10093288)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  WAKO Hiroshi (60158607)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  YOMO Tetsuya (00222399)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  ISHIMORI Koichiro (20192487)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  YUTANI Katsuhide (90089889)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  KATAOKA Mikio (30150254)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  KUSHIDA Takashi (00013516)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  YAMAGATA Yuriko (40183678)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  SUZUKI Masanori (70206530)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  ENDO Kojin (70292315)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  UNNO Michiaki (70282043)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  小笠原 直毅 (10110553)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  和田 昭允 (10011462)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  村越 道生 (70570901)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 37.  小山 眞 (10465487)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  浜名 洋 (90551549)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  飯田 浩司 (00451534)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  野口 俊之 (90172775)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  美宅 茂樹 (10107542)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  森島 績 (50026093)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  梅山 秀明 (20050619)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  諏訪 牧子 (30242241)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  伊倉 貞吉 (50251393)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  北尾 彰朗 (30252422)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  後藤 祐児 (40153770)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  KIDOKORO Shunichi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  UCHIKAWA Makoto
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  VOLKER Erdma
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 51.  ERDMANN Volker A.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 52.  ERDMANN Volk
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 53.  HIROKI Hayashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 54.  TAWA Keiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 55.  SHIRAI Akihiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 56.  ONITSUKA Masayoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 57.  ABE Hiroyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 58.  KUROTANI Reiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 59.  中西 猛
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 60.  北原 亮
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 61.  OLIVEIRA Daniel
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 62.  阿尻 雅文
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 63.  大政 健史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 64.  中澤 光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 65.  二井手 哲平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 66.  安部 聡
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 67.  笠井 均
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 68.  中澤 徹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 69.  高見 誠一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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