MAKI Hisaji 真木寿治

Researcher Number	20199649
Other IDs
External Links
Affiliation (based on the past Project Information) *help	1994 – 2016: Nara Institute of Science and Technology, バイオサイエンス研究科, 教授 1999 – 2001: 奈良先端科学技術大学院大学, バイオ, 教授 1998: 奈良先端科学技術大学院大学バイオ, 教授 1997 – 1998: NARA INSTITUTE OF SCIENCE AND TECHNOLOGY,GRADUATE SCHOOL OF BIOSCIENCES,PROFESSO, バイオサイエンス研究所, 教授 1994 – 1998: 奈良先端科学技術大学院大学, 教授 … More 1996: 奈良先端科学技術大学院大学, バイオサイエンス, 教授 1996: NARA INSTIT.SCI.TECH,PROFESSOR, バイオサイエンス科, 教授 1993: Institute of Molecular and Cellular Bioscience University of Tokyo, 分子細胞生物学研究所, 助教授 1993: 東京大学, 応用微生物研究所, 助教授 1992: 東京大学応用微生物研究所, 助教授 1987 – 1991: 九州大学, 医学部, 助手 1988 – 1990: 九州大学, 医学部・生化学, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Molecular biology / Molecular biology / Genetics/Chromosome dynamics / Genetics/Genome dynamics Except Principal Investigator Molecular biology / Molecular biology / 環境影響評価(含放射線生物学) / 遺伝 / Cell biology
Keywords	Principal Investigator DNA複製 / 突然変異 / DNA修復 / 遺伝子 / DNAポリメラーゼ / DNA replication / 遺伝学 / 遺伝的不安定性 / 大腸菌 / ゲノム … More / ミューテーター / 分子生物学 / 酸素ラジカル / DNA repair / DNA polymerase / 染色体再編・維持 / 複製フォーク / ノックアウトマウス / 繰り返し配列 / フレームシフト / ミスマッチ修復 / DNA損傷 / mutation / genome / gene / genetics / frameshift / proofreading / DNA damage / KO mouse / mutator / 修復 / DNA報復 / 校正機能 / SOS repair / SOS response / Error-pronerepair / Mutagen / Carciniogen / SOS修復 / SOS応答 / 誤りがち修復 / 変異原 / 発がん物質 / Mismatch repair / Mutator / Molecular Biology / Esherichia coli / 進化 / 活性酸素 / 遺伝病 / がん / 自然突然変異 / がん遺伝子 / DNA組換え / DNA / 酵素ラジカル / 複製エラー / 生化学 / ミューテーター遺伝子 / DNA構造 / クロ-ニング / ミュ-テ-タ- / 老化 … More Except Principal Investigator 突然変異 / DNA修復 / DNA複製 / 遺伝情報 / がん遺伝子 / イニシエーション / 自然突然変異 / DNAポリメラーゼ / Cdc7 / 活性酸素 / 化学発癌 / 変異圧 / 遺伝暗号 / 遺伝子工学 / 塩基置換 / 塩基組成 / コドン / 細胞周期 / 前癌病変 / 転写調節 / DNA修復酵素 / 誘導突然変異 / アルキル化剤 / ミューテーター / DNA repair / RF-C複合体 / rpsL gene / 発がん / 遺伝病 / 相同的組換え / 組換え修復 / 除去修復 / DNA鋳型活性 / 細胞動態 / 発癌リスク / 宿主・臓器環境 / DNA付加体形成 / イニシエーター / 複製装置 / チェックポイント / レプリソーム / 分子マシナリー / DNA組み換え酵素 / DNA複製速度 / DNA複製フォーク / DNA組換え酵素 / DNAコーミング / 一分子解析 / SOS応答 / DNA損傷応答 / 複製フォーク / Spontaneous Mutation / DNA Polymerase / Transcriptional Control / Induced Mutation / Alkylating Agent / DNA Repair Enzyme / DNA合成酵素 / methyltransferase / induced mutation / spontaneous mutation / gene cloning / alkylating agent / DNA polymerase / replication fidelity / 発がんの抑制 / 遺伝子のクローニング / アルキル科剤 / メチルトランスフェラーゼ / メチルトランスフェラ-ゼ / 遺伝子クロ-ニング / DNAポリメラ-ゼ / 複製精度 / mutation spectra / spontaneous carcinogenesis / spontaneous mutagenesis / transgenic mice / DNA repair-deficient mouse / 8-oxo-guanine / oxidative DNA damage / 8-oxo-dGTPase / 酸化ストレス / 放射線誘発突然変異 / 変異スペクトラム / 自然発がん / 遺伝子操作マウス / DNA修復欠損 / 8-オキソグアニン / 酸化的DNA損傷 / Genetic disease / Carcinogenesis / Mutagenesis / Homologous recombination / Recombination repair / Nucleotide excision repair / 相同的組換之 / 組換之修復 / Checkpoint control / Dbf4 protein kinase / Mcm2-7 complex / DNA helicase / Lagging strand synthesis apparatus / Leading strand synthesis apparatus / Eukaryotic chromosomal DNA replication / 細胞周期チェックポイント / PCNA / Lagging鎖合成装置 / Leading鎖合成装置 / 真核生物染色体DNA複製 / Dbf4複合体 / Mcm蛋白複合体 / ヘリカーゼ / Bloom症候群原因遺伝子産物 / チェックポイント制御 / Dbf4プロテインキナーゼ / Mcm2-7蛋白複合体 / DNAヘリカーゼ / Lagging鎖複製装置 / Leading鎖複製装置 / 真核生物染色体複製機構 / DNA polymerase complex / RF-C complex / Dbf4 protein kinase complex / Budding yeast / Insect cells / Baculovirus expression vector / Expression vector / DNA Replication protein complex / RFC複合体 / Cdc7-Dbf4複合体 / YACベクター / バキュロウイルスベクター / DNAポリメラーゼ複合体 / Cdc7-Dbf4 protein kinase複合体 / 出芽酵母 / 昆虫細胞 / バキューロウイルスベクター / 多量発現ベクター / DNA複製複合体 / Shuttle vector / Mutagenicity test / Mutagen / Genotoxicity test / Tumorigenicity screening / Mutation ; in vivo / Transgenic mouse / rpsL遺伝子 / マウス / 分子遺伝学 / 突然変異検定 / ypsL / シャトルベクター / 変異原性試験 / 環境変異原 / 遺伝毒性検定 / 発がんリスク評価 / rpsL / トランスジェニックマウス / Cancer Metastasis / DNA Repair / Signal Transduction / Tumor Suppressor Genes / Oncogenes / German-Japanese Collaborative Program in Cancer Research / French-Japanese Collaborative Program in Cancer Research / International Exchange Program / がん抑制遣伝子 / がん遣伝子 / 2国間共同研究 / ヒトゲノム / がん転移 / がん細胞 / シグナル伝達 / がん抑制遺伝子 / 発癌の修飾 / 減数分裂 / 転写 / 組換え / 修復 / 複製 / 遺伝情報維持 / DNAトランスアクション / DNA付加体 / イニシエ-タ- / イニシエ-ション / DNAポリメラ-ゼIII / dGTPase / GC含量 / 大腸菌 / ミュ-テ-タ- Less

DNA損傷部位で停止した転写装置が及ぼす複製フォークの進行阻害とその回復機構Principal Investigator
- Principal Investigator
  
  真木寿治
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
Molecular mechanisms of chromosomal rearrangement caused by topological changing of DNA.Principal Investigator
- Principal Investigator
  
  Maki Hisaji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Genetics/Chromosome dynamics
- Research Institution
  Nara Institute of Science and Technology
Study of mechanisms that decrease speed of replication fork progression in DNA damage response
- Principal Investigator
  
  Akiyama Masahiro
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Nara Institute of Science and Technology
ＤＮＡ損傷部位で停止した転写装置が及ぼす複製フォークの進行阻害とその回復機構Principal Investigator
- Principal Investigator
  
  真木寿治
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
Molecular mechanisms of recovery of stalled DNA replication forkPrincipal Investigator
- Principal Investigator
  
  MAKI Hisaji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Nara Institute of Science and Technology
Molecular mechanisms controlling spontaneous mutationsPrincipal Investigator
- Principal Investigator
  
  MAKI Hisaji
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
自然突然変異の原因としてのヌクレオチド除去修復の修復DNA合成エラーPrincipal Investigator
- Principal Investigator
  
  真木寿治
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  Nara Institute of Science and Technology
Molecular mechanisms of recovery of stalled DNA replication forkPrincipal Investigator
- Principal Investigator
  
  HISAJI Maki
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Nara Institute of Science and Technology
Molecular mechanisms generating and suppressing spontaneous mutationsPrincipal Investigator
- Principal Investigator
  
  MAKI Hisaji
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
Development of the evaluation system for mutagenesis using DNA repair-deficient mice
- Principal Investigator
  
  TSUZUKI Teruhisa
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Kyushu University
Molecular mechanisms of mutagenesis caused by transletion DNA synthesisPrincipal Investigator
- Principal Investigator
  
  MAKI Hisaji
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Molecular biology
- Research Institution
  Nara Institute of Science and Technology
突然変異の分子病態Principal Investigator
- Principal Investigator
  
  真木寿治
- Project Period (FY)
  1996 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nara Institute of Science and Technology
Molecular Mechanism of Chromosomal DNA Replication Apparatus
- Principal Investigator
  
  SUGINO Akio
- Project Period (FY)
  1996 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Research Institute for Microbial Diseases, Osaka University
Molecular Mechanisms of Genomic Instability and DNA Repair
- Principal Investigator
  
  HANAOKA Fumio
- Project Period (FY)
  1996 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
DNA修復欠損の分子病態
- Principal Investigator
  
  花岡文雄
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Osaka University
Studies of Somatic Mutation Frequencies and Spectra with a Sensitive and Efficient Detection Method by Using Transgenic Mice.
- Principal Investigator
  
  GONDO Yoichi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  遺伝
- Research Institution
  TOKAI UNIVERSITY
EXPRESSION OF EUKARYOTIC DNA REPLICATION PROTEIN COMPLEXS AND THEIR SIMPLE PURIFICATION METHOD
- Principal Investigator
  
  SUGINO Akio
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Molecular biology
- Research Institution
  Osaka University
自然突然変異の発生と抑制の制御機構Principal Investigator
- Principal Investigator
  
  真木寿治
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nara Institute of Science and Technology
DNAトランスアクションと遺伝情報の安定性
- Principal Investigator
  
  HANAOKA Fumio
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Osaka University
宿主・臓器環境とイニシエーションリスクの変動
- Principal Investigator
  
  石川隆俊
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
強力な変異原性ヌクレオチド8-OH-dGTPを特異的に分解するヒト細胞由来の酵素Principal Investigator
- Principal Investigator
  
  真木寿治
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
アルキル化剤による変異誘発とその抑制機構に及ぼす標的遺伝子の転写の影響Principal Investigator
- Principal Investigator
  
  真木寿治
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Molecular Mechanisms of Spontaneous Mutagenesis Caused by Oxygen RadicalsPrincipal Investigator
- Principal Investigator
  
  HISAJI Maki
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Nara Institute of Science and Technology
  The University of Tokyo
宿主・臓器環境とイニシエーションリスクの変動
- Principal Investigator
  
  石川隆俊
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
Cooperation and information exchange with European countries.
- Principal Investigator
  
  KUROKI Toshio
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  University of Tokyo
化学発癌におけるイニシエ-ション機構の解析
- Principal Investigator
  
  石川隆俊
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
染色体GC含量を制御するミュ-テ-タ-遺伝子(mut T)の分子遺伝学的研究
- Principal Investigator
  
  堀内嵩
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
コドン選択
- Principal Investigator
  
  池村淑道
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Genetics
コドン選択
- Principal Investigator
  
  池村淑道
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Genetics
コドン選択
- Principal Investigator
  
  池村淑道
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Genetics
化学発癌におけるイニシエーション機構の解析
- Principal Investigator
  
  ISHIKAWA Takatoshi
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
化学発癌におけるイニシエーション機構の解析
- Principal Investigator
  
  石川隆俊
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Japanese Foundation For Cancer Research
大腸菌染色体複製における忠実度制御の分子機構の研究Principal Investigator
- Principal Investigator
  
  真木寿治
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Mechanisms for induction and suppression of spontaneous and induced mutations
- Principal Investigator
  
  SEKIGUCHI Mutsuo
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Overseas Scientific Survey.
- Research Institution
  Kyushu University
Maintenance of Genetic Information and Mutagenesis Mechanisms
- Principal Investigator
  
  SEKIGUCHI Mutsuo
- Project Period (FY)
  1986 – 1990
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Research Institution
  Kyushu University

All 2016 2015 2014 2013 2012 2010 2009 2008 2007 2006 2005 2002 Other

All Journal Article Presentation Book

[Book] DNA Polymerase III, Bacterial. In: Lennarz W.J. and Lane M.D. (eds.) The Encyclopedia of Biological Chemistry, vol. 22013
- Author(s)
  Hisaji Maki
- Total Pages
  3
- Publisher
  Academic Press
- Data Source
  KAKENHI-PUBLICLY-23131518
[Book] バイオインフォマティクス辞典2006
- Author(s)
  真木寿治, 他
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-17013060
[Book] バイオインフォマティクス辞典2006
- Author(s)
  真木寿治
- Publisher
  共立出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17370063
[Book] 遺伝子から生命をみる-分子生物学の誕生と発展-2006
- Author(s)
  真木寿治
- Publisher
  共立出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17370063
[Book] 遺伝子から生命をみる-分子生物学の誕生と発展-2006
- Author(s)
  真木寿治, 他
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-17013060
[Journal Article] Replication fork progression is paused in two large chromosomal zones flanking the DNA replication origin in Escherichia coli2016
- Author(s)
  Masahiro Tatsumi Akiyama, Taku Oshima, Onuma Chumsakul, Shu Ishikawa and Hisaji Mak
- Journal Title
  
  Genes to Cells
  
  Volume: 21 Issue: 8 Pages: 907-914
- DOI
  10.1111/gtc.12388
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25440009, KAKENHI-PROJECT-26450090
[Journal Article] Long inverted repeat transiently stalls DNA replication by forming hairpin structures on both leading and lagging strands2016
- Author(s)
  Lai P.J., Lim C.T., Le H.P., Katayama T., Leach D.R.F, Furukohri A＊., Maki H.
- Journal Title
  
  Genes to Cells
  
  Volume: 21 Issue: 2 Pages: 136-145
- DOI
  10.1111/gtc.12326
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25840009, KAKENHI-PROJECT-25291077
[Journal Article] A novel mode of nuclease action is revealed by the bacterial Mre11/Rad50 complex2015
- Author(s)
  Lim C.T., Lai P.J., Leach D.R.F, Maki H., Furukohri A
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 43 Pages: 9804-9816
- DOI
  10.1093/nar/gkv855
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25840009, KAKENHI-PROJECT-25291077
[Journal Article] Recombinase and translesion DNA polymerase decrease the speed of replication fork progression during the DNA damage response in Escherichia coli cells.2015
- Author(s)
  Tan K.W., Pham M.T., Furukohri A, Maki H. and Akiyama T.M.
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 43 Issue: 3 Pages: 1715-1725
- DOI
  10.1093/nar/gkv044
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25131713, KAKENHI-PROJECT-25291077, KAKENHI-PROJECT-25440009, KAKENHI-PROJECT-25840009
[Journal Article] Short CCG repeat in huntingtin gene is an obstacle for replicative DNA polymerases, potentially hampering progression of replication fork.2015
- Author(s)
  Le HP, Masuda Y, Tsurimoto T, Maki S, Katayama T, Furukohri A, Maki H.
- Journal Title
  
  Genes Cells.
  
  Volume: 10 Issue: 10 Pages: 817-833
- DOI
  10.1111/gtc.12275
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25440011, KAKENHI-PUBLICLY-26114714, KAKENHI-PROJECT-15H02818, KAKENHI-PROJECT-25840009, KAKENHI-PROJECT-25291077
[Journal Article] DNA polymeraes IV mediates efficient and quick recovery at N2-dG adducts.2014
- Author(s)
  Ikeda M, Furukohri A, Philippin G, Loechler E, Akiyama MT, Katayama T, Fuchs RP, Maki H.
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 42 Issue: 13 Pages: 8461-8472
- DOI
  10.1093/nar/gku547
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25131713, KAKENHI-PROJECT-25291077, KAKENHI-PROJECT-25440009, KAKENHI-PROJECT-25840009
[Journal Article] A single-molecule approach to DNA replication in Escherichia coli cells demonstrated that DNA polymerase III is a major determinant of fork speed.2013
- Author(s)
  Pham M.T., Tan K.W., Sakumura Y., Okumura K., Maki H. and Akiyama T.M.
- Journal Title
  
  Molecular Microbiology
  
  Volume: 90 Issue: 3 Pages: 584-596
- DOI
  10.1111/mmi.12386
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25131713, KAKENHI-PROJECT-25291077, KAKENHI-PROJECT-25440009
[Journal Article] Near-full-length REV3L appears to be a scarce maternal factor in Xenopus laevis eggs that changes qualitatively in early embryonic development.2010
- Author(s)
  Ogawara D., Muroya T., Yamauchi K., Iwamoto TA., Yagi Y., Yamashita Y., Waga S., Akiyama M., Maki H.
- Journal Title
  
  DNA Repair(Amst)誌 9巻1号
  
  Pages: 90-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013060
[Journal Article] Near-full-length REV3L appears to be a scarce maternal factor in Xenopus laevis eggs that changes qualitatively in early embryonic development.2010
- Author(s)
  Ogawara D., Muroya T., Yamauchi K., Iwamoto TA., Yagi Y., Yamashita Y., Waga S., Akiyama M., Maki H.
- Journal Title
  
  DNA Repair(Amst)誌 9巻1号
  
  Pages: 90-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370068
[Journal Article] Abundance ofribosomal RNA gene copies maintains genome integrity.2010
- Author(s)
  Ide S., Miyazaki T., Maki H., Kobayashi T.
- Journal Title
  
  Science誌 327巻
  
  Pages: 693-696
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370068
[Journal Article] Abundance of ribosomal RNA gene copies maintains genome integrity.2010
- Author(s)
  Ide S., Miyazaki T., Maki H., Kobayashi T.
- Journal Title
  
  Science誌 327巻
  
  Pages: 693-696
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013060
[Journal Article] Overproduction of Escherichia coli DNA polymerase Ding (Pol IV)inhibits replication fork progression and is lethal.2008
- Author(s)
  Uchida K., Fumkohri A., Shinozaki Y., Mori T.,Ogawara D., Kanaya S., Nohmi T., Maki H., Akiyama M.
- Journal Title
  
  Molecular Microbiology誌 70巻3号
  
  Pages: 608-622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370068
[Journal Article] Spontaneous Mutagenesis Associated with Nucleotide Excision Repair in Escherichia coli.2008
- Author(s)
  Hasegawa K., Yoshiyama K., Maki H.
- Journal Title
  
  Genes to Cells誌 13巻
  
  Pages: 459-469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013060
[Journal Article] Overproduction of Escherichia coli DNA polymerase DinB (Pol IV) inhibits replication fork progression and is lethal.2008
- Author(s)
  Uchida K., Furukohri A., Shinozaki Y., Mori T., Ogawara D., Kanaya S., Nohmi T., Maki H., Akiyama M.
- Journal Title
  
  Molecular Microbiology誌 70巻3号
  
  Pages: 608-622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013060
[Journal Article] Spontaneous Mutagenesis Associated with Nucleotide Excision Repair in Escherichia coli.2008
- Author(s)
  Hasegawa K., Yoshiyama K., Maki H.
- Journal Title
  
  Genes to Cells誌 13巻
  
  Pages: 459-469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370068
[Journal Article] A dynamic polymerase exchange with Escherichia coli pol IV replacing pol III on the sliding clamp.2008
- Author(s)
  Furukohri A., Goodman M.F., Maki H.
- Journal Title
  
  J Biol Chem誌 283巻17号
  
  Pages: 11260-11269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013060
[Journal Article] A dynamic polymerase exchange with Escherichia coli pol IV replacing pol III on the sliding clamp.2008
- Author(s)
  Furukohri A., Goodman M.F., Maki H.
- Journal Title
  
  J Biol Chem誌 283巻17号
  
  Pages: 11260-11269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370068
[Journal Article] MUTYH-null mice are susceptible to spontaneous and oxidative-stress-induced intestinal tumorigenesis.2007
- Author(s)
  Sakamoto K., Tominaga Y., Yamauchi K., Nakatsu Y., Sakumi K., Yoshiyama K., Egashira A., Kura S., Yao T., Tsuneyoshi M., Maki H., Nakabeppu Y., Tsuzuki, T.
- Journal Title
  
  Cancer Research誌 67巻14号
  
  Pages: 6599-6604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013060
[Journal Article] Abnormality in initiation program of DNA replication is monitored by the highly repetitive rDNA array on chromosome XII in budding yeast.2007
- Author(s)
  Ide, S., Watanabe, K., Watanabe, H., Shirahige, K., Kobayashi, T., Maki, H.
- Journal Title
  
  Mol Cell Biol誌 27巻
  
  Pages: 568-578
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013060
[Journal Article] Roles of RecA protein in spontaneous mutagenesis in Escherichia coli.2007
- Author(s)
  Kanie, S., Horibata, K., Kawano, M., Isogawa, A., Sakai, A., Matsuo, N., Nakanishi, M., Hasegawa, K., Yoshiyama, K., Maki, H.
- Journal Title
  
  Genes Genet Systems誌 82巻2号
  
  Pages: 99-108
- NAID
  10024393945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013060
[Journal Article] The dnaE173 mutator mutation confers on the a subunit of Escherichia coli DNA polymerase III a capacity for highly processive DNA synthesis and stable binding to primer-template DNA.2007
- Author(s)
  Yanagihara F., Yoshida S., Sugaya Y., Maki H.
- Journal Title
  
  Genes Genet Systems誌 82巻4号
  
  Pages: 273-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013060
[Journal Article] Impact of reactive oxygen species on spontaneous mutagenesis in Escherichia coli.2006
- Author(s)
  Sakai, A., Nakanishi, M., Yoshiyama, K., Maki, H.
- Journal Title
  
  Genes Cells誌 11巻
  
  Pages: 767-778
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013060
[Journal Article] Double-stranded DNA binding, an unusual property of DNA polymerase epsilon, promotes epigenetic silencing in Saccharomyces cerevisiae.2006
- Author(s)
  Tsubota, T., Tajima, R., Ode, K., Kubota, H., Fukuhara, N., Kawabata, T., Maki, S., Maki, H.
- Journal Title
  
  J Biol Chem誌 281巻
  
  Pages: 32898-32908
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013060
[Journal Article] DNA polymerasesηandκare responsible for error-free translesion DNA synthesis activity over a cis-syn thymine dimer in Xenopus laevis oocyte extracts.2005
- Author(s)
  Yagi, Y., Ogawara, D., Iwai, S., Hanaoka, F., Akiyama, M., Maki, H.
- Journal Title
  
  DNA Repair (Amst)誌 4巻
  
  Pages: 1252-1269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013060
[Journal Article] RNAi-mediated silencing of OsGEN-L (OsGEN-like), a new member of the RAD2/XPG nuclease family, causes male sterility by defect of microspore development in rice.2005
- Author(s)
  Moritoh, S., Miki, D., Akiyama, M., Kawahara, M., Izawa, T., Maki, H., Shimamoto, K.
- Journal Title
  
  Plant Cell Physiol誌 46巻
  
  Pages: 699-715
- NAID
  10015661666
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013060
[Journal Article] Origins of spontaneous mutations : Specificity of base-substitution, frameshift and sequence-substitution mutageneses.2002
- Author(s)
  Maki, H.
- Journal Title
  
  Annu.Rev.Genet. 36
  
  Pages: 279-303
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12213082
[Presentation] recAまたはdinB遺伝子の過剰発現による複製フォーク速度の低下2015
- Author(s)
  Tan Kang Wei、Pham Minh Tuan、古郡麻子、真木寿治、秋山昌広
- Organizer
  日本遺伝学会・第87回大会
- Place of Presentation
  東北大学（宮城県仙台市）
- Year and Date
  2015-09-25
- Data Source
  KAKENHI-PROJECT-25440009
[Presentation] 大腸菌の栄養環境が酸化ＤＮＡ損傷と活性酸素種に与える影響2015
- Author(s)
  布瀬翔平, Tom Conrad, 安藤さやか, 豊本奈美江, 中村葵, 秋山昌広, 真木壽治
- Organizer
  日本遺伝学会第８７回大会
- Place of Presentation
  東北大学、宮城県仙台市
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] DNA損傷応答による複製マシナリーの進行速度の低下2015
- Author(s)
  Tan Kang Wei、Pam Minh Tuan、古郡麻子、真木壽治、秋山昌広
- Organizer
  第12回21世紀大腸菌研究会
- Place of Presentation
  琵琶湖グランドホテル（滋賀県大津市）
- Year and Date
  2015-06-04
- Data Source
  KAKENHI-PROJECT-25440009
[Presentation] recAまたはdinB遺伝子の過剰発現による複製フォーク速度の低下2015
- Author(s)
  Tan Kang Wei, Pham Minh Tuan, 古郡麻子, 真木壽治, 秋山昌広
- Organizer
  日本遺伝学会第８７回大会
- Place of Presentation
  東北大学、宮城県仙台市
- Year and Date
  2015-09-25
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] 大腸菌のrecAまたはdinB遺伝子の過剰発現による複製フォーク進行の遅延2015
- Author(s)
  Tan Kang Wei、Pham Minh Tuan、古郡麻子、真木寿治、秋山昌広
- Organizer
  第38回・日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25440009
[Presentation] 大腸菌損傷乗り越え型DNA Polymerase IVの複製フォークにおける役割2015
- Author(s)
  古郡麻子、池田美央、秋山昌広、片山勉、Robert P. Fuchs、真木壽治
- Organizer
  第12回21世紀大腸菌研究会
- Place of Presentation
  琵琶湖グランドホテル（滋賀県大津市）
- Year and Date
  2015-06-04
- Data Source
  KAKENHI-PROJECT-25440009
[Presentation] Biochemical analysis reveals a novel action of bacterial Mre11/Rad50 complex2015
- Author(s)
  古郡麻子, Lim Chew Theng, Lai Pey Jiun, David R.F. Leach, 真木壽治
- Organizer
  日本遺伝学会第８７回大会
- Place of Presentation
  東北大学、宮城県仙台市
- Year and Date
  2015-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] 大腸菌の栄養環境が酸化ＤＮＡ損傷と活性酸素種に与える影響2015
- Author(s)
  布瀬翔平、Tom Conrad、安藤さやか、豊本奈美江、中村葵、秋山昌広、真木壽治
- Organizer
  日本遺伝学会・第87回大会
- Place of Presentation
  東北大学（宮城県仙台市）
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-25440009
[Presentation] ヌクレオチドプールとＤＮＡの酸化損傷に起因する突然変異2015
- Author(s)
  真木壽治
- Organizer
  日本遺伝学会第８７回大会
- Place of Presentation
  東北大学、宮城県仙台市
- Year and Date
  2015-09-24
- Invited
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] 大腸菌のrecAまたはdinB遺伝子の過剰発現による複製フォーク進行の遅延2015
- Author(s)
  Tan Kang Wei, Pham Minh Tuan, 古郡麻子, 真木壽治, 秋山昌広
- Organizer
  日本分子生物学会第３８回年会
- Place of Presentation
  神戸ポートアイランド、兵庫県神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] 大腸菌DNAポリメラーゼＩの細胞内機能におけるβクランプの役割2015
- Author(s)
  山本崇史, 真木壽治
- Organizer
  日本遺伝学会第８７回大会
- Place of Presentation
  東北大学、宮城県仙台市
- Year and Date
  2015-09-25
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] 低ｐＨ培養環境は大腸菌細胞内の酸化ＤＮＡ損傷レベルを上昇させる2015
- Author(s)
  宮原亮太, 真木壽治
- Organizer
  日本遺伝学会第８７回大会
- Place of Presentation
  東北大学、宮城県仙台市
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] A sequence flanking CAG/CTG trinucleotide repeats in the gene responsible for Hiungtington's disease has a potential for blocking DNA polymerases and may cause the replication fork arrest.2013
- Author(s)
  Phuong Hang Le、古郡麻子、増田雄司、片山　勉、真木智子、真木寿治
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  慶応大学日吉キャンパス、横浜市
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] 大腸菌細胞のDNA複製フォーク速度の単分子解析.2013
- Author(s)
  Pham Minh Tuan、Tang Kang Wei、作村諭一、奥村克純、真木寿治、秋山昌広
- Organizer
  第10回 21世紀大腸菌研究会
- Place of Presentation
  ラフォーレ修善寺、伊豆市
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] 大腸菌 Pol IV の働きにより複製フォークはN2-dG DNA損傷を効率よく乗り越えて進行を続ける2013
- Author(s)
  古郡麻子、池田美央、秋山昌広、片山　勉、Robert P. Fuchs、真木寿治
- Organizer
  第22回 DNA複製･組換え･修復ワークショップ
- Place of Presentation
  ホテルニュー水戸屋、仙台市
- Data Source
  KAKENHI-PUBLICLY-25131713
[Presentation] 自然突然変異とDNAポリメラーゼの分子機構研究2013
- Author(s)
  真木寿治
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  慶応大学日吉キャンパス、横浜市
- Invited
- Data Source
  KAKENHI-PUBLICLY-25131713
[Presentation] 自然突然変異とDNAポリメラーゼの分子機構研究2013
- Author(s)
  真木寿治
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  慶応大学日吉キャンパス、横浜市
- Invited
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] A sequence flanking CAG/CTG trinucleotide repeats in the gene responsible for Hiungtington's disease has a potential for blocking DNA polymerases and may cause the replication fork arrest.2013
- Author(s)
  Phuong Hang Le、古郡麻子、増田雄司、片山　勉、真木智子、真木寿治
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  慶応大学日吉キャンパス、横浜市
- Data Source
  KAKENHI-PUBLICLY-25131713
[Presentation] 大腸菌 Pol IV の働きにより複製フォークはN2-dG DNA損傷を効率よく乗り越えて進行を続ける2013
- Author(s)
  古郡麻子、池田美央、秋山昌広、片山　勉、Robert P. Fuchs、真木寿治
- Organizer
  第22回 DNA複製･組換え･修復ワークショップ
- Place of Presentation
  ホテルニュー水戸屋、仙台市
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] 大腸菌細胞におけるDNA複製フォークの進行速度に関する一分子解析.2013
- Author(s)
  Pham Minh Tuan、Tang Kang Wei、作村諭一、奥村克純、真木寿治、秋山昌広
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド、神戸市
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] 大腸菌細胞のDNA複製フォーク速度の単分子解析.2013
- Author(s)
  Pham Minh Tuan、Tang Kang Wei、作村諭一、奥村克純、真木寿治、秋山昌広
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  慶応大学日吉キャンパス、横浜市
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] 大腸菌細胞のDNA複製フォーク速度の単分子解析.2013
- Author(s)
  Pham Minh Tuan、Tang Kang Wei、作村諭一、奥村克純、真木寿治、秋山昌広
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  慶応大学日吉キャンパス、横浜市
- Data Source
  KAKENHI-PUBLICLY-25131713
[Presentation] 大腸菌細胞におけるDNA複製フォークの進行速度に関する一分子解析.2013
- Author(s)
  Pham Minh Tuan、Tang Kang Wei、作村諭一、奥村克純、真木寿治、秋山昌広
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド、神戸市
- Data Source
  KAKENHI-PUBLICLY-25131713
[Presentation] 大腸菌細胞における複製フォークの進行速度に関する一分子解析2013
- Author(s)
  Pham Minh Tuan、Tan Kang Wei、作村諭一、奥村克純、真木寿治、秋山昌広
- Organizer
  第22回DNA複製･組換え･修復ワークショップ
- Place of Presentation
  ホテルニュー水戸屋、仙台市
- Data Source
  KAKENHI-PROJECT-25440009
[Presentation] 大腸菌細胞のDNA複製フォーク速度の単分子解析.2013
- Author(s)
  Pham Minh Tuan、Tang Kang Wei、作村諭一、奥村克純、真木寿治、秋山昌広
- Organizer
  第10回 21世紀大腸菌研究会
- Place of Presentation
  ラフォーレ修善寺、伊豆市
- Data Source
  KAKENHI-PUBLICLY-25131713
[Presentation] 大腸菌細胞のDNA複製フォーク速度の単分子解析2013
- Author(s)
  Pham Minh Tuan、Tan Kang Wei、作村諭一、奥村克純、真木寿治、秋山昌広
- Organizer
  第10回21世紀大腸菌研究会
- Place of Presentation
  ラフォーレ修善寺、伊豆市
- Data Source
  KAKENHI-PROJECT-25440009
[Presentation] DNA polymerase III is a major determinant of replication fork speed in Escherichia coli cells2013
- Author(s)
  Tuan Minh Pham, Kang Wei Tan, Yuichi Sakumura, Katsuzumi Okumura, Hisaji Maki and Masahiro Tatsumi Akiyama
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  慶應義塾大学日吉キャンパス、横浜市
- Data Source
  KAKENHI-PROJECT-25440009
[Presentation] 大腸菌細胞における複製フォークの進行速度に関する一分子解析.2013
- Author(s)
  Pham Minh Tuan、Tang Kang Wei、作村諭一、奥村克純、真木寿治、秋山昌広
- Organizer
  第22回 DNA複製･組換え･修復ワークショップ
- Place of Presentation
  ホテルニュー水戸屋、仙台市
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] 大腸菌細胞における複製フォークの進行速度に関する一分子解析.2013
- Author(s)
  Pham Minh Tuan、Tang Kang Wei、作村諭一、奥村克純、真木寿治、秋山昌広
- Organizer
  第22回 DNA複製･組換え･修復ワークショップ
- Place of Presentation
  ホテルニュー水戸屋、仙台市
- Data Source
  KAKENHI-PUBLICLY-25131713
[Presentation] 大腸菌細胞のDNA複製フォーク速度の単分子解析2013
- Author(s)
  Pham Minh Tuan、Tan Kang Wei、作村諭一、奥村克純、真木寿治、秋山昌広
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  慶應義塾大学日吉キャンパス、横浜市
- Data Source
  KAKENHI-PROJECT-25440009
[Presentation] DNA polymerase III is a major determinat of replication fork speed in Escherichia coli.2013
- Author(s)
  Pham Minh Tuan、Tang Kang Wei、作村諭一、奥村克純、真木寿治、秋山昌広
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  慶応大学日吉キャンパス、横浜市
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] DNA polymerase III is a major determinat of replication fork speed in Escherichia coli.2013
- Author(s)
  Pham Minh Tuan、Tang Kang Wei、作村諭一、奥村克純、真木寿治、秋山昌広
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  慶応大学日吉キャンパス、横浜市
- Data Source
  KAKENHI-PUBLICLY-25131713
[Presentation] Superoxide Mutagenesis: An Overview of Outcome and a Possible Involvement of Glyoxal.2012
- Author(s)
  Hisaji Maki
- Organizer
  U.S.-Japan DNA Repiar Meeting
- Place of Presentation
  National Conference Center, Virginia, USA
- Year and Date
  2012-04-12
- Invited
- Data Source
  KAKENHI-PUBLICLY-23131518
[Presentation] Hyper-processive and slower DNA chain elongation catalysed by dnaE173 DNA polymerase III holoenzyme.2012
- Author(s)
  Hisaji Maki
- Organizer
  Cantoblanco Workshop on "Polymerases involved in DNA replication, repair and,mutagenesis. From basic knowledge to biotechnological applications"
- Place of Presentation
  Centro de Biolog#237;a Molecular Severo Ochoa, Madrid, Spain
- Year and Date
  2012-06-05
- Invited
- Data Source
  KAKENHI-PUBLICLY-23131518
[Presentation] Effects of a long inverted‐repeat on dynamics of Escherichia coli DNA replication fork.2012
- Author(s)
  Hisaji Maki
- Organizer
  3rd Erling Seeberg Symposium
- Place of Presentation
  Trondheim and Orland, Norway
- Year and Date
  2012-06-22
- Invited
- Data Source
  KAKENHI-PUBLICLY-23131518
[Presentation] Spontaneous Mutagenesis Associated with Nucleotide Excision Repair in Escherichia coli.2010
- Author(s)
  真木寿治
- Organizer
  The 57th NIRR Conference THE DYNAMIC GENOME
- Place of Presentation
  岡崎カンファレンスセンター(愛知県)
- Year and Date
  2010-10-16
- Data Source
  KAKENHI-PROJECT-20370068
[Presentation] 酸素ラジカルに起因する自然突然変異の発生と抑制の分子機構2010
- Author(s)
  真木寿治
- Organizer
  日本遺伝学会第82回大会
- Place of Presentation
  北海道大学高等教育機能開発総合センター(北海道)
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-20370068
[Presentation] 酸素ラジカルに起因する自然突然変異の誘発経路の発見とその展開2010
- Author(s)
  真木寿治
- Organizer
  変異機構研究会・第23回夏の学校
- Place of Presentation
  小牧東部市民センター、小牧勤労センター(愛知県)
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-20370068
[Presentation] Spontaneous Mutagenesis Associated with Nucleotide Excision Repair in Escherzchla colz.2010
- Author(s)
  沙魚川公子、愿山郁、真木寿治
- Organizer
  The 57th NIBB Conference THE DYNAMIC GENOME
- Place of Presentation
  岡崎カンファレンスセンター
- Year and Date
  2010-10-16
- Data Source
  KAKENHI-PROJECT-20370068
[Presentation] 酸素ラジカルに起因する自然突然変異の誘発経路の発見とその展開2010
- Author(s)
  真木寿治
- Organizer
  変異機構研究会・第23回夏の学校
- Place of Presentation
  小牧東部市民センター・小牧勤労センター
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-20370068
[Presentation] 大腸菌DNAポリメラーゼIの配列置換変異抑制機能2009
- Author(s)
  真木寿治, 他5名
- Organizer
  日本遺伝学会第81回大会
- Place of Presentation
  信州大学理学部
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-20370068
[Presentation] 大腸菌DNAポリメラーゼIの配列置換変異抑制機能2009
- Author(s)
  真木寿治
- Organizer
  日本遺伝学会第81回大会
- Place of Presentation
  信州大学理学部A棟および講義棟
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-17013060
[Presentation] 大腸菌DNA ポリメラーゼIの配列置換変異抑制機能2009
- Author(s)
  真木寿治
- Organizer
  日本遺伝学会第81回大会
- Place of Presentation
  信州大学理学部(長野県)
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-20370068
[Presentation] 大腸菌DNAポリメラーゼIの配列置換変異抑制機能2009
- Author(s)
  真木寿治
- Organizer
  日本遺伝学会第81回大会
- Place of Presentation
  信州大学理学部(長野県)
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-17013060
[Presentation] Spontaneous mutagenesis associated with nucleotide excision repair in Escherichia coli.2008
- Author(s)
  Maki, H.
- Organizer
  The 6th International 3R (DNA Replication, Recombination and Repair)Symposium
- Place of Presentation
  TSUMAGOI RESORT, Kakegawa, Shizuoka, Japan
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20370068
[Presentation] A dynamic polymerise exchange with Escherichia coli Pol IV replacing Pol III on the sliding clamp.2008
- Author(s)
  古郡麻子、Goodman, M.、真木寿治
- Organizer
  The 6th International 3R (DNA Replication, Recombination and Repair) Symposium
- Place of Presentation
  ヤマハリゾートつま恋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20370068
[Presentation] 大腸菌ヌクレオチド除去修復による自然突然変異の誘発経路2008
- Author(s)
  沙魚川公子、愿山郁、真木寿治
- Organizer
  日本遺伝学会第80回大会
- Place of Presentation
  名古屋大学工学部IB電子情報館
- Year and Date
  2008-09-03
- Data Source
  KAKENHI-PROJECT-20370068
[Presentation] Anew role of RDH54 in genome maintenance.2008
- Author(s)
  山口和勇、梅津桂子、真木寿治
- Organizer
  The 6th International 3R(DNA Replication, Recombination and Repair)Symposium
- Place of Presentation
  ヤマハリゾートつま恋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20370068
[Presentation] Spontaneous mutagenesis associated with nucleotide excision repair in Escherichia coli2008
- Author(s)
  Maki, H
- Organizer
  The 6th International 3R (DNA Replication, Recombination and Repair) Symposium
- Place of Presentation
  TSUMAGOI RESORT, Kakegawa, Shizuoka, Japan
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-17013060
[Presentation] A dynamic polymerase exchange with Escherichia coli pol IV replacing pol III on the sliding clamp.2008
- Author(s)
  古郡麻子、Goodman, M.、真木寿治
- Organizer
  XX International Congress of Genetics(第20回国際遺伝学会)
- Place of Presentation
  The congress center(ドイツ)
- Data Source
  KAKENHI-PROJECT-20370068
[Presentation] Spontaneous Mutagenesis Associated with Nucleotide Excision Repair in Escherichia coliSpontaneous Mutagenesis Associated with Nucleotide Excision Repair in Escherichia coli.2008
- Author(s)
  沙魚川公子、愿山郁、真木寿治
- Organizer
  XX International Congress of Genetics(第20回国際遺伝学会)
- Place of Presentation
  The congress center(ドイツ)
- Data Source
  KAKENHI-PROJECT-20370068
[Presentation] Spontaneous mutagenesis associated with nucleotide excision repair in Escherichia coli.2008
- Author(s)
  沙魚川公子、愿山郁、真木寿治
- Organizer
  The 6th International 3R(DNA Replication, Recombination and Repair)Symposium
- Place of Presentation
  ヤマハリゾートつま恋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20370068
[Presentation] 複製開始制御異常に起因する染色体異常と細胞死の誘発;rDNA領域の役割2007
- Author(s)
  真木寿治
- Organizer
  日本遺伝学会第79回大会
- Place of Presentation
  岡山大学理学部・創立50周年記念館
- Year and Date
  2007-09-19
- Data Source
  KAKENHI-PROJECT-17013060
[Presentation] A new pathway of spontaneous mutagenesis: repair DNA synthesis error during unnecessary action of nucleotide excision repair.2007
- Author(s)
  真木寿治
- Organizer
  第3回日米DNA修復会議
- Place of Presentation
  クレセントホテル(仙台市)
- Year and Date
  2007-05-08
- Data Source
  KAKENHI-PROJECT-17013060
[Presentation] Involvement of rDNA locus in monitoring abnormal initiation program of chromosomal replication by DNA damage check-point control2007
- Author(s)
  M. Hisaji
- Organizer
  The 79th Annual Meeting of the Genetics Society of Japan
- Place of Presentation
  Okayama University, Japan
- Year and Date
  2007-09-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17370063
[Presentation] 複製開始制御異常に起因する染色体異常と細胞死の誘発;rDNA領域の役割2007
- Author(s)
  真木寿治
- Organizer
  日本遺伝学会第79回大会
- Place of Presentation
  岡山大学理学部
- Year and Date
  2007-09-19
- Data Source
  KAKENHI-PROJECT-17013060
[Presentation] 複製開始制御異常に起因する染色体異常と細胞死の誘発;rDNA領域の役割2007
- Author(s)
  真木寿治
- Organizer
  日本遺伝学会第79回大会
- Place of Presentation
  岡山大学理学部・創立50周年記念館
- Year and Date
  2007-09-19
- Data Source
  KAKENHI-PROJECT-17370063
[Presentation] A new pathway of spontaneous mutagenesis: repair DNA synthesis error during unnecessary action of nucleotide excision repair.2007
- Author(s)
  真木寿治
- Organizer
  第3回日米DNA修復会議
- Place of Presentation
  クレセントホテル(仙台市)
- Year and Date
  2007-05-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17370063
[Presentation] A new pathway of spontaneous mutagenesis: repair DNA synthesis error during unnecessary action of nucleotide excision repair2007
- Author(s)
  M. Hisaji
- Organizer
  3rd Japan-US DNA Repair Meeting
- Place of Presentation
  Akiu, Sendai, Japan
- Year and Date
  2007-05-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17370063
[Presentation] 複製開始制御異常に起因する染色体異常と細胞死の誘発;rDNA領域の役割2007
- Author(s)
  真木寿治
- Organizer
  日本遺伝学会第79回大会
- Place of Presentation
  岡山大学理学部
- Year and Date
  2007-09-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17370063
[Presentation] DNAポリメラーゼIV(DinB)による複製フォーク進行阻害の回復機構2005
- Author(s)
  真木寿治
- Organizer
  日本遺伝学会第77回大会
- Place of Presentation
  国立オリンピック記念青少年総合センター
- Year and Date
  2005-09-28
- Data Source
  KAKENHI-PROJECT-17013060
[Presentation] Mechanisms of DNA polymerase switching upon translesion DNA synthesis: A novel action of DinB protein on the DNA chain elongation by DNA polymerase III holoenzyme.2005
- Author(s)
  真木寿治
- Organizer
  The 5th International 3R (DNA Replication, Recombination and Repair) Symposium
- Place of Presentation
  淡路夢舞台国際会議場
- Year and Date
  2005-11-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17370063
[Presentation] Involvement of rDNA locus in monitoring abnormality in the initiation program of chromosomal DNA replication by DNA damage checkpoint control2005
- Author(s)
  M. Hisaji
- Organizer
  51st NIBB Conference
- Place of Presentation
  Okazaki Conference Center, National Institute for Basic Biology, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17370063
[Presentation] 自然突然変異の発生と抑制の分子機構2005
- Author(s)
  真木寿治
- Organizer
  日本環境変異原学会公開シンポジウム
- Place of Presentation
  共立薬科大学記念講堂
- Year and Date
  2005-05-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17370063
[Presentation] Mechanisms of DNA polymerase switching upon translesion DNA synthesis: A novel action of DinB protein on the DNA chainelongation by DNA polymerase III holoenzyme2005
- Author(s)
  M. Hisaji
- Organizer
  The 5th International 3R (DNA Replication, Recombination and Repair) Symposium
- Place of Presentation
  Awaji Yumebutai International Conference Center, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17370063
[Presentation] Involvement of rDNA locus in monitoring abnormality in the initiation program of chromosomal DNA replication by DNA damage checkpoint control.2005
- Author(s)
  真木寿治
- Organizer
  第51回基礎生物学研究所コンファレンス
- Place of Presentation
  基礎生物学研究所
- Year and Date
  2005-11-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17370063
[Presentation] 自然突然変異の発生と抑制の分子機構2005
- Author(s)
  真木寿治
- Organizer
  日本環境変異原学会公開シンポジウム
- Place of Presentation
  共立薬科大学記念講堂
- Year and Date
  2005-05-28
- Data Source
  KAKENHI-PROJECT-17013060
[Presentation] Involvement of rDNA locus in monitoring abnormality in the initiation program of chromosomal DNA replication by DNA damage checkpoint control.2005
- Author(s)
  真木寿治
- Organizer
  第51回基礎生物学研究所コンファレンス
- Place of Presentation
  基礎生物学研究所
- Year and Date
  2005-11-06
- Data Source
  KAKENHI-PROJECT-17013060
[Presentation] DNAポリメラーゼIV(DinB)による複製フォーク進行阻害の回復機構2005
- Author(s)
  真木寿治
- Organizer
  日本遺伝学会第77回大会
- Place of Presentation
  国立オリンピック記念青少年総合センター
- Year and Date
  2005-09-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17370063
[Presentation] Escherichia coli DNA polymerase IV mediates quick recpovery of repliaction forks stalled at N2-dG adducts.
- Author(s)
  Furukohri, A., Ikead, M., Akiyama, M., Katayama, T., Fuchs R.P., and Maki, H.
- Organizer
  The 9th 3R International Symposium
- Place of Presentation
  御殿場高原ホテル（静岡県、御殿場市）
- Year and Date
  2014-11-11 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-25440009
[Presentation] 大腸菌のSOS応答による複製フォークの進行速度の低下
- Author(s)
  Tang Kang Wei、Pham Minh Tuan、古郡麻子、奥村克純、真木寿治、秋山昌広
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜・神奈川県・横浜市
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] 大腸菌のSOS応答による複製フォーク速度の減速
- Author(s)
  Tang Kang Wei、Pham Minh Tuan、古郡麻子、奥村克純、真木寿治、秋山昌広
- Organizer
  日本遺伝学会第86回大会
- Place of Presentation
  長浜バイオ大学・滋賀県・長浜市
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PUBLICLY-25131713
[Presentation] Escherichia coli DNA polymerase IV mediates quick recpovery of repliaction forks stalled at N2-dG adducts.
- Author(s)
  Furukohri, A., Ikead, M., Akiyama, M., Katayama, T., Fuchs R.P., and Maki, H.
- Organizer
  The 9th 3R International Symposium
- Place of Presentation
  御殿場高原ホテル・静岡県・御殿場市
- Year and Date
  2014-11-11 – 2014-11-21
- Data Source
  KAKENHI-PUBLICLY-25131713
[Presentation] A single molecule approach to DNA replication in Escherichia coli cells demonstrated that DNA polymerae III is a major determinant of fork speed.
- Author(s)
  Pham, TM., Tan, K.W., Sakumura, Y., Okumura,K., Furukohri, A., Maki, H.,and Akiyama, T.M.
- Organizer
  The 9th 3R International Symposium
- Place of Presentation
  御殿場高原ホテル・静岡県・御殿場市
- Year and Date
  2014-11-11 – 2014-11-21
- Data Source
  KAKENHI-PUBLICLY-25131713
[Presentation] Escherichia coli DNA polymerase IV mediates quick recpovery of repliaction forks stalled at N2-dG adducts
- Author(s)
  Furukohri, A., Ikead, M., Akiyama, M., Katayama, T., Fuchs R.P., and Maki, H.
- Organizer
  DNA polymerases: Biology, Diseases and Biomediacal Appliatiuon Conference 2014
- Place of Presentation
  Robinson collage (Cambridge, England)
- Year and Date
  2014-08-31 – 2014-09-04
- Data Source
  KAKENHI-PROJECT-25440009
[Presentation] A short CCG run in the Huntingtin gene is an obstacle for replicative DNA polymerases, potentially hampering fork progression.
- Author(s)
  Hang, L.P., Furukohri, A., Masuda, Y., Maki, S., Katayama, T., Fuchs R.P., and Maki, H.
- Organizer
  DNA polymerases: Biology, Diseases and Biomediacal Appliatiuon Conference 2014
- Place of Presentation
  Robinson college, Cambridge (England)
- Year and Date
  2014-08-31 – 2014-09-04
- Data Source
  KAKENHI-PUBLICLY-25131713
[Presentation] A single molecule approach to DNA replication in Escherichia coli cells demonstrated that DNA polymerae III is a major determinant of fork speed.
- Author(s)
  Pham, TM., Tan, K.W., Sakumura, Y., Okumura,K., Furukohri, A., Maki, H.,and Akiyama, T.M.
- Organizer
  The 9th 3R International Symposium
- Place of Presentation
  御殿場高原ホテル・静岡県・御殿場市
- Year and Date
  2014-11-11 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] A single molecule approach to DNA replication in Escherichia coli cells demonstrated that DNA polymerae III is a major determinant of fork speed.
- Author(s)
  Pham, TM., Tan, K.W., Sakumura, Y., Okumura,K., Furukohri, A., Maki, H.,and Akiyama, T.M.
- Organizer
  DNA polymerases: Biology, Diseases and Biomediacal Appliatiuon Conference 2014
- Place of Presentation
  Robinson college, Cambridge (England)
- Year and Date
  2014-08-31 – 2014-09-04
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] 大腸菌損傷乗り越え型 DNA Polymerase IV の複製フォークにおける役割
- Author(s)
  古郡麻子、池田美央、西川義人、秋山昌広、片山　勉、Robert P. Fuchs、真木寿治
- Organizer
  日本遺伝学会第86回大会
- Place of Presentation
  長浜バイオ大学・滋賀県・長浜市
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PUBLICLY-25131713
[Presentation] Escherichia coli DNA polymerase IV mediates quick recpovery of repliaction forks stalled at N2-dG adducts.
- Author(s)
  Furukohri, A., Ikead, M., Akiyama, M., Katayama, T., Fuchs R.P., and Maki, H.
- Organizer
  DNA polymerases: Biology, Diseases and Biomediacal Appliatiuon Conference 2014
- Place of Presentation
  Robinson college, Cambridge (England)
- Year and Date
  2014-08-31 – 2014-09-04
- Data Source
  KAKENHI-PUBLICLY-25131713
[Presentation] A single molecule approach to DNA replication in Escherichia coli cells demonstrated that DNA polymerae III is a major determinant of fork speed.
- Author(s)
  Pham, TM., Tan, K.W., Sakumura, Y., Okumura,K., Furukohri, A., Maki, H.,and Akiyama, T.M.
- Organizer
  DNA polymerases: Biology, Diseases and Biomediacal Appliatiuon Conference 2014
- Place of Presentation
  Robinson college, Cambridge (England)
- Year and Date
  2014-08-31 – 2014-09-04
- Data Source
  KAKENHI-PUBLICLY-25131713
[Presentation] A single molecule approach to DNA replication in Escherichia coli cells demonstrated that DNA polymerae III is a major determinant of fork speed
- Author(s)
  Pham, TM., Tan, K.W., Sakumura, Y., Okumura,K., Furukohri, A., Maki, H.,and Akiyama, T.M.
- Organizer
  DNA polymerases: Biology, Diseases and Biomediacal Appliatiuon Conference 2014
- Place of Presentation
  Robinson collage (Cambridge, England)
- Year and Date
  2014-08-31 – 2014-09-04
- Data Source
  KAKENHI-PROJECT-25440009
[Presentation] Escherichia coli DNA polymerase IV mediates quick recpovery of repliaction forks stalled at N2-dG adducts.
- Author(s)
  Furukohri, A., Ikead, M., Akiyama, M., Katayama, T., Fuchs R.P., and Maki, H.
- Organizer
  The 9th 3R International Symposium
- Place of Presentation
  御殿場高原ホテル・静岡県・御殿場市
- Year and Date
  2014-11-11 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] A single molecule approach to DNA replication in Escherichia coli cells demonstrated that DNA polymerae III is a major determinant of fork speed
- Author(s)
  Pham, TM., Tan, K.W., Sakumura, Y., Okumura,K., Furukohri, A., Maki, H.,and Akiyama, T.M.
- Organizer
  The 9th 3R International Symposium
- Place of Presentation
  御殿場高原ホテル（静岡県、御殿場市）
- Year and Date
  2014-11-11 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-25440009
[Presentation] A short CCG run in the Huntingtin gene is an obstacle for replicative DNA polymerases, potentially hampering fork progression.
- Author(s)
  Hang, L.P., Furukohri, A., Masuda, Y., Maki, S., Katayama, T., Fuchs R.P., and Maki, H.
- Organizer
  DNA polymerases: Biology, Diseases and Biomediacal Appliatiuon Conference 2014
- Place of Presentation
  Robinson college, Cambridge (England)
- Year and Date
  2014-08-31 – 2014-09-04
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] 大腸菌損傷乗り越え型 DNA Polymerase IV の複製フォークにおける役割
- Author(s)
  古郡麻子、池田美央、西川義人、秋山昌広、片山　勉、Robert P. Fuchs、真木寿治
- Organizer
  日本遺伝学会第86回大会
- Place of Presentation
  長浜バイオ大学（滋賀県、長浜市）
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-25440009
[Presentation] 大腸菌のSOS応答による複製フォークの進行速度の低下
- Author(s)
  Tang Kang Wei、Pham Minh Tuan、古郡麻子、奥村克純、真木寿治、秋山昌広
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25440009
[Presentation] 大腸菌のSOS応答による複製フォークの進行速度の低下
- Author(s)
  Tang Kang Wei、Pham Minh Tuan、古郡麻子、奥村克純、真木寿治、秋山昌広
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜・神奈川県・横浜市
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-25131713
[Presentation] 大腸菌のSOS応答による複製フォーク速度の減速
- Author(s)
  Tang Kang Wei、Pham Minh Tuan、古郡麻子、真木寿治、秋山昌広
- Organizer
  日本遺伝学会第86回大会
- Place of Presentation
  長浜バイオ大学（滋賀県、長浜市）
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-25440009
[Presentation] 大腸菌損傷乗り越え型 DNA Polymerase IV の複製フォークにおける役割
- Author(s)
  古郡麻子、池田美央、西川義人、秋山昌広、片山　勉、Robert P. Fuchs、真木寿治
- Organizer
  日本遺伝学会第86回大会
- Place of Presentation
  長浜バイオ大学・滋賀県・長浜市
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] Escherichia coli DNA polymerase IV mediates quick recpovery of repliaction forks stalled at N2-dG adducts.
- Author(s)
  Furukohri, A., Ikead, M., Akiyama, M., Katayama, T., Fuchs R.P., and Maki, H.
- Organizer
  DNA polymerases: Biology, Diseases and Biomediacal Appliatiuon Conference 2014
- Place of Presentation
  Robinson college, Cambridge (England)
- Year and Date
  2014-08-31 – 2014-09-04
- Data Source
  KAKENHI-PROJECT-25291077
[Presentation] 大腸菌のSOS応答による複製フォーク速度の減速
- Author(s)
  Tang Kang Wei、Pham Minh Tuan、古郡麻子、奥村克純、真木寿治、秋山昌広
- Organizer
  日本遺伝学会第86回大会
- Place of Presentation
  長浜バイオ大学・滋賀県・長浜市
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-25291077

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MAKI Hisaji 真木 寿治

Research Projects

Research Products

Co-Researchers

DNA損傷部位で停止した転写装置が及ぼす複製フォークの進行阻害とその回復機構Principal Investigator

Principal Investigator

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Molecular mechanisms of chromosomal rearrangement caused by topological changing of DNA.Principal Investigator

Principal Investigator

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ＤＮＡ損傷部位で停止した転写装置が及ぼす複製フォークの進行阻害とその回復機構Principal Investigator

Principal Investigator

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Molecular mechanisms of recovery of stalled DNA replication forkPrincipal Investigator

Principal Investigator

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Molecular mechanisms controlling spontaneous mutationsPrincipal Investigator

Principal Investigator

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自然突然変異の原因としてのヌクレオチド除去修復の修復DNA合成エラーPrincipal Investigator

Principal Investigator

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Molecular mechanisms of recovery of stalled DNA replication forkPrincipal Investigator

Principal Investigator

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Molecular mechanisms generating and suppressing spontaneous mutationsPrincipal Investigator

Principal Investigator

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Principal Investigator

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Molecular mechanisms of mutagenesis caused by transletion DNA synthesisPrincipal Investigator

Principal Investigator

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突然変異の分子病態Principal Investigator

Principal Investigator

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Principal Investigator

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MAKI Hisaji 真木寿治